CN202814985U - PCT (procalcitonin)/CRP (C-reactive protein) whole-blood test paper tape - Google Patents
PCT (procalcitonin)/CRP (C-reactive protein) whole-blood test paper tape Download PDFInfo
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- CN202814985U CN202814985U CN 201220300892 CN201220300892U CN202814985U CN 202814985 U CN202814985 U CN 202814985U CN 201220300892 CN201220300892 CN 201220300892 CN 201220300892 U CN201220300892 U CN 201220300892U CN 202814985 U CN202814985 U CN 202814985U
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Abstract
The utility model provides a PCT (procalcitonin)/CRP (C-reactive protein) whole-blood test paper tape. The test paper tape comprises a first sample pad (2), a second sample pad (3), a gold-labeled pad (4) coated with a gold-labeled antibody, an envelope membrane (5) and absorbent paper (6) which are sequentially and closely overlapped with one another from left to right on a test paper tape bottom liner (1), wherein a quality control line (9) coated with a rabbit antimouse IgG (immunoglobulin G) antibody and two parallel testing lines are formed on the envelope membrane,, and the two parallel testing lines include a testing line (7) for coating a PCT monoclonal antibody, and a testing line (8) for coating a CRP monoclonal antibody. The test paper tape can be used for testing a whole-blood sample, is capable of rapidly testing double indexes of PCT/CRP with one sampling, and is convenient and easy to operate.
Description
Technical field
The utility model belongs to the clinical medical inspection field, is specifically related to a kind of PCT/CRP whole blood test test strips.
Background technology
Procalcitonin (PCT) is a kind of protein that is comprised of 116 amino acid, and its level in blood plasma raises when serious bacterium, fungi, parasitic infection and pyemia and MOFE.PCT has reflected the active degree of systemic inflammatory response.At present, PCT comes antidiastole bacillary and non-bacterial infection and inflammation as an acute parameter.
C reactive protein (CRP) is the pod membrane C polysaccharide combination of a kind of energy and streptococcus pneumonia, the synthetic gamma Globulin of liver cell when body is subject to microorganism invasion or tissue damage etc. and stimulates, molecular weight is about 105KD, and trace is present in (about 580ng/ml) in the Healthy Human Serum.In be inflamed disease or tissue damage 6～8 hours, serum or plasma C-reactive protein amount raises rapidly, and reaches the peak at 48～72 hours, but along with the state of an illness is improved or its content of institutional framework functional rehabilitation also recovers normal.Therefore the level of C reactive protein in serum or the blood plasma can be used as and judges to have or not infection, disease whether to be in the index of active stage.
For the diseases such as systemic inflammatorome, septicemia, septic shock, chronic kidney hypofunction are diagnosed, Chinese patent 200710073309.3 utilizes the PCT test kit to diagnose, and Chinese patent 201010213990.9 utilizes the CRP detection kit to diagnose.Yet in clinical diagnosis, the diagnostic result of single index is inaccurate sometimes, and, also do not have at present can enough whole bloods PCT/CRP to be detected, therefore need to seek more convenient effective diagnostic means.
Summary of the invention
The problem that exists in order to solve above-mentioned prior art, the utility model provides a kind of rapid sensitive, convenience, has quantitatively detected a kind of PCT/CRP whole blood test test strips of clinical sample (whole blood/serum/plasma), this test strips is on the one hand by utilizing Procalcitonin monoclonal antibody and high-sensitive C-reactive protein monoclonal antibody simultaneously PCT, CRP to be detected, and by the Multilayer Samples pad filtration of whole blood realized detection to whole blood sample on the other hand.
A kind of PCT/CRP whole blood test test strips that the utility model provides, what comprise on the test strips end liner 1 from left to right successively tight overlap joint is gold mark pad 4, coated film 5 and the thieving paper 6 of ground floor sample pad 2, second layer sample pad 3, coated with gold labeling antibody, described coated film is provided with the nature controlling line 9 of a coated rabbit anti-mouse igg antibody, also be provided with two parallel detection lines,, the detection line 7 of coated Procalcitonin monoclonal antibody, the detection line 8 of another coated c reactive protein monoclonal antibody.
The Procalcitonin monoclonal antibody that described golden labeling antibody is colloid gold label and the c reactive protein monoclonal antibody of colloid gold label.
Article two, parallel detection line, its sequence of positions can be exchanged.
The ground floor sample pad of described PCT/CRP whole blood test test strips and the material of second layer sample pad can be polyester film, glass fibre element film, whole blood filter membrane.Described nature controlling line is rabbit anti-mouse igg antibody.
More preferably, described second layer sample pad covers on the gold mark pad fully.
The PCT/CRP whole blood test test strips that the utility model provides has following useful effect:
1, can directly detect as sample with whole blood, increase the convenience that detects.
2, only need an application of sample, can supply the PCT/CRP joint detection results by Quick, testing result is more effective.
Description of drawings
Fig. 1 is the cross-sectional configuration synoptic diagram of whole blood test test strips of the present utility model.
Wherein: 1, end liner; 2, ground floor sample pad; 3, second layer sample pad; 4, the gold mark pad of coated with gold labeling antibody; 5, coated film; 6, thieving paper; 7, the detection line of coated Procalcitonin monoclonal antibody; 8, the detection line of coated c reactive protein monoclonal antibody; 9, the nature controlling line of coated rabbit anti-mouse igg antibody.
Embodiment
Below in conjunction with the drawings and specific embodiments the utility model is carried out clear, complete description.
In conjunction with Fig. 1, a kind of PCT/CRP whole blood test test strips, what comprise on the test strips end liner 1 from left to right successively tight overlap joint is gold mark pad 4, coated film 5 and the thieving paper 6 of ground floor sample pad 2, second layer sample pad 3, coated with gold labeling antibody, described coated film is provided with the nature controlling line of a coated rabbit anti-mouse igg antibody, also be provided with two parallel detection lines, article one, be the detection line 7 of coated Procalcitonin monoclonal antibody, another is the detection line 8 of coated c reactive protein monoclonal antibody.
Testing sample can be serum, blood plasma, whole blood.
Second layer sample pad is shorter than ground floor sample pad, is conducive to the stickup of its left end and end liner.
Article two, parallel detection line, its sequence of positions can be exchanged.
The ground floor sample pad of described PCT/CRP whole blood test test strips and the material of second layer sample pad can be polyester film, glass fibre element film, whole blood filter membrane, second layer sample pad covers on the gold mark pad fully, can more effectively stop red blood cell, make sample exhibition layer more abundant.
Using method:
Gather whole blood, serum or blood plasma and put into clean sample cup, with sample spot at test strips sample pad place, observations in 8～10 minutes.Positive: two or three aubergine band occurs, and nature controlling line 9 districts that are positioned at coated rabbit anti-mouse igg antibody are if detection line 7 districts of another coated Procalcitonin monoclonal antibody can judge that the PCT index is positive; Equally, if another is positioned at detection line 8 districts of coated c reactive protein monoclonal antibody, can judge that the CRP index is positive; If red zone all appears in the detection line 7 of coated Procalcitonin monoclonal antibody and detection line 8 districts of coated c reactive protein monoclonal antibody, can judge that PCT and CRP index are all positive.Negative: an aubergine band appears in the nature controlling line district of coated rabbit anti-mouse igg antibody, red zone does not all appear in the detection line 7 of coated Procalcitonin monoclonal antibody and detection line 8 districts of coated c reactive protein monoclonal antibody, but shows and do not contain CRP in the sample or CRP content is lower than sensing range.Red zone does not appear in the nature controlling line district of coated rabbit anti-mouse igg antibody, shows that test paper is invalid.
The above only is preferred embodiment of the present invention, is not to be the restriction of the present invention being made other form, and any those skilled in the art may utilize the technology contents of above-mentioned announcement to be changed or be modified as the equivalent embodiment of equivalent variations.But every technical solution of the present invention content that do not break away to any simple modification, equivalent variations and remodeling that above embodiment does, still belongs to the protection domain of technical solution of the present invention according to technical spirit of the present invention.
Claims (4)
1. PCT/CRP whole blood test test strips, what comprise on the test strips end liner (1) from left to right successively tight overlap joint is gold mark pad (4), coated film (5) and the thieving paper (6) of ground floor sample pad (2), second layer sample pad (3), coated with gold labeling antibody, described coated film is provided with the nature controlling line (9) of a coated rabbit anti-mouse igg antibody, also be provided with two parallel detection lines, article one, be the detection line (7) of coated Procalcitonin monoclonal antibody, another is the detection line (8) of coated c reactive protein monoclonal antibody.
2. a kind of PCT/CRP whole blood test test strips according to claim 1 is characterized in that Procalcitonin monoclonal antibody that described golden labeling antibody is colloid gold label and the c reactive protein monoclonal antibody of colloid gold label.
3. a kind of PCT/CRP whole blood test test strips according to claim 1 is characterized in that described two parallel detection lines, and its sequence of positions can be exchanged.
4. a kind of PCT/CRP whole blood test test strips according to claim 1 is characterized in that the ground floor sample pad of described test strips and the material of second layer sample pad can be polyester film, glass fibre element film, whole blood filter membrane.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 201220300892 CN202814985U (en) | 2012-06-26 | 2012-06-26 | PCT (procalcitonin)/CRP (C-reactive protein) whole-blood test paper tape |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 201220300892 CN202814985U (en) | 2012-06-26 | 2012-06-26 | PCT (procalcitonin)/CRP (C-reactive protein) whole-blood test paper tape |
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| Publication Number | Publication Date |
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| CN202814985U true CN202814985U (en) | 2013-03-20 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN 201220300892 Expired - Lifetime CN202814985U (en) | 2012-06-26 | 2012-06-26 | PCT (procalcitonin)/CRP (C-reactive protein) whole-blood test paper tape |
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Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103344767A (en) * | 2013-06-20 | 2013-10-09 | 凌中鑫 | Up-converting phosphor (UCP) test paper strip for PCT/CRP (procalcitonin/c reactive protein) joint detection |
| CN103454425A (en) * | 2013-08-24 | 2013-12-18 | 管义东 | Reagent strip for detecting PCT (procalcitonin) and preparation method of reagent strip |
| CN103645321A (en) * | 2013-12-03 | 2014-03-19 | 张超 | Test paper for screening procalcitonin and preparation method of test paper |
| CN104316702A (en) * | 2014-05-30 | 2015-01-28 | 广州万孚生物技术股份有限公司 | PCT (procalcitonin) and CRP quantitative joint inspection chromatography test strip and preparation method thereof |
| CN105467116A (en) * | 2015-11-28 | 2016-04-06 | 宁波美康生物科技股份有限公司 | Convenient procalcitonin detection kit |
| CN108089013A (en) * | 2018-01-05 | 2018-05-29 | 潍坊科瑞斯生物科技有限公司 | The preparation method of fluorometric reagent in a kind of dog Procalcitonin detection kit and the detection kit |
| CN116577498A (en) * | 2023-07-13 | 2023-08-11 | 济南玖方生物科技有限公司 | Application of sample pad for detecting HIV antibody in urine, test strip and sample pad treatment fluid |
-
2012
- 2012-06-26 CN CN 201220300892 patent/CN202814985U/en not_active Expired - Lifetime
Cited By (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103344767A (en) * | 2013-06-20 | 2013-10-09 | 凌中鑫 | Up-converting phosphor (UCP) test paper strip for PCT/CRP (procalcitonin/c reactive protein) joint detection |
| CN103454425A (en) * | 2013-08-24 | 2013-12-18 | 管义东 | Reagent strip for detecting PCT (procalcitonin) and preparation method of reagent strip |
| CN103645321A (en) * | 2013-12-03 | 2014-03-19 | 张超 | Test paper for screening procalcitonin and preparation method of test paper |
| CN104316702A (en) * | 2014-05-30 | 2015-01-28 | 广州万孚生物技术股份有限公司 | PCT (procalcitonin) and CRP quantitative joint inspection chromatography test strip and preparation method thereof |
| CN104316702B (en) * | 2014-05-30 | 2016-08-31 | 广州万孚生物技术股份有限公司 | PCT Yu CRP quantitative joint inspection chromatograph test strip and preparation method thereof |
| CN105467116A (en) * | 2015-11-28 | 2016-04-06 | 宁波美康生物科技股份有限公司 | Convenient procalcitonin detection kit |
| CN108089013A (en) * | 2018-01-05 | 2018-05-29 | 潍坊科瑞斯生物科技有限公司 | The preparation method of fluorometric reagent in a kind of dog Procalcitonin detection kit and the detection kit |
| CN116577498A (en) * | 2023-07-13 | 2023-08-11 | 济南玖方生物科技有限公司 | Application of sample pad for detecting HIV antibody in urine, test strip and sample pad treatment fluid |
| CN116577498B (en) * | 2023-07-13 | 2023-09-12 | 济南玖方生物科技有限公司 | Application of sample pad for detecting HIV antibody in urine, test strip and sample pad treatment fluid |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| C56 | Change in the name or address of the patentee |
Owner name: GETEIN BIOTECH, INC. Free format text: FORMER NAME: NANJING EGG-BASED BIOTECHNOLOGY CO., LTD. |
|
| CP01 | Change in the name or title of a patent holder |
Address after: Liuhe District of Nanjing City, Jiangsu province 211505 Yangtze River Industrial Development Zone Bo Fu Road No. 9 Patentee after: GETEIN BIOTECH, Inc. Address before: Liuhe District of Nanjing City, Jiangsu province 211505 Yangtze River Industrial Development Zone Bo Fu Road No. 9 Patentee before: Nanjing Getein Biotechnology Co.,Ltd. |
|
| CX01 | Expiry of patent term |
Granted publication date: 20130320 |
|
| CX01 | Expiry of patent term |