CN202808659U - Assembly line for heparin sodium purification - Google Patents
Assembly line for heparin sodium purification Download PDFInfo
- Publication number
- CN202808659U CN202808659U CN 201220521292 CN201220521292U CN202808659U CN 202808659 U CN202808659 U CN 202808659U CN 201220521292 CN201220521292 CN 201220521292 CN 201220521292 U CN201220521292 U CN 201220521292U CN 202808659 U CN202808659 U CN 202808659U
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- waist
- heparin sodium
- reactor
- centrifuge
- still
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Abstract
The utility model discloses an assembly line for heparin sodium purification. The assembly line for the heparin sodium purification comprises a reaction kettle and is characterized by further comprising a butterfly type centrifuge, a tubular bowl centrifuge, a reaction kettle with a kettle waist infusion device and a closed type flat centrifuge, the bottom of the reaction kettle is connected with the butterfly type centrifuge through a pipe, the butterfly type centrifuge is connected with the tubular bowl centrifuge through a pipe, the tubular bowl centrifuge is connected with the reaction kettle with the kettle waist infusion device through a pipe, and the bottom of the reaction kettle with the kettle waist infusion device is connected with the closed type flat centrifuge through a pipe. The assembly line for the heparin sodium purification can efficiently remove protein substances and chondroitin sulfate or substances similar to the chondroitin sulfate in animal extract crude products of a crude product heparin sodium or similar heparin sodium. Highest total titer yield of a product purification process can reach above 89%.
Description
Technical field
The utility model relates to chemical substance extraction equipment field, relates in particular to be used to the streamline that carries out heparin sodium purification.
Background technology
The enterprise that is engaged in heparin sodium purification adopts the conventional process techniques of repetition heparin sodium crude extraction more, use traditional extraction equipment such as the common vessel of band stirring, the wide aperture filter plant of filtration silica gel resin etc., crude product is carried out again or repeatedly extracts (resin absorption, wash-out, precipitation etc.) to obtain the lower product of protein foreign matter content, adopt again afterwards other technologies (centrifugal such as tubular type) that remaining protein impurity that can't flush away in the product is removed.Increase to a great extent the consumption of supplementary material such as solvent, resin etc. owing to repeat the way of resin absorption, wash-out, increased many production costs; Also owing to the multiple adsorb wash-out loses portioned product, cause the yield of purifying products not high.Therefore need the new purified stream waterline of design one cover, solve the deficiency of above-mentioned existence.
Summary of the invention
The purpose of this utility model provides a kind of Decrease production cost, improves the streamline that is used for carrying out heparin sodium purification of purification yield.
The technical solution adopted in the utility model is:
Be used for carrying out the streamline of heparin sodium purification, comprise reactor, also comprise butterfly centrifugal machine, tubular-bowl centrifuge, have reactor and the closed dull and stereotyped whizzer of still waist pumping device, described reactor bottom is connected with the butterfly centrifugal machine by pipeline, described butterfly centrifugal machine is connected with tubular-bowl centrifuge by pipeline, described tubular-bowl centrifuge is connected with the reactor with still waist pumping device by pipeline, and described reactor bottom with still waist pumping device is connected with closed dull and stereotyped whizzer by pipeline.
In the reactor with still waist pumping device, its still waist pumping device is fixed in the side of reactor, described still waist pumping device comprises visor, handle, hand lever and pumping pipe, described visor is located at the reactor side, described handle is individually fixed in top and the middle and lower part of hand lever, and described hand lever is flexibly connected with the conical gear that is fixed on the pumping pipe by the conical gear of its bottom.
The utility model can high-level efficiency be removed in the animal extracts crude product of crude heparin sodium or similar heparin sodium protein matter and chondroitin sulfate or is similar to the chondroitin sulfate material.The total titer yield of purifying products technique reaches as high as more than 89%.
Description of drawings
Fig. 1 is the streamline synoptic diagram that the present invention is used to carry out heparin sodium purification.
Fig. 2 is the reactor structural representation with still waist pumping device.
Wherein: 1, reactor, 2, the butterfly centrifugal machine, 3, tubular-bowl centrifuge, 4, have a reactor of still waist pumping device, 5, closed dull and stereotyped whizzer, 6, handle, 7, hand lever, 8, pumping pipe, 9, conical gear, 10, to visor.
Embodiment
As shown in Figure 1, be used for carrying out the streamline of heparin sodium purification, comprise reactor 1, also comprise butterfly centrifugal machine 2, tubular-bowl centrifuge 3, have reactor 4 and the closed dull and stereotyped whizzer 5 of still waist pumping device, reactor 1 bottom is connected with butterfly centrifugal machine 2 by pipeline, butterfly centrifugal machine 2 is connected with tubular-bowl centrifuge 3 by pipeline, tubular-bowl centrifuge 3 is connected with the reactor 4 with still waist pumping device by pipeline, and reactor 4 bottoms with still waist pumping device are connected with closed dull and stereotyped whizzer 5 by pipeline.
As shown in Figure 2, in the reactor 4 with still waist pumping device, its still waist pumping device is fixed in the side of reactor, still waist pumping device comprises visor 10, handle 6, hand lever 7 and pumping pipe 8, visor 10 is located at the reactor side, handle 6 is individually fixed in top and the middle and lower part of hand lever 7, and hand lever 7 is flexibly connected with the conical gear 9 that is fixed on the pumping pipe 8 by the conical gear 9 of its bottom.When needs carry out drawing liquid, rotate the handle 6 on the hand lever 7, hand lever 7 bottoms by and pumping pipe 8 between conical gear 9 combination drive pumping pipes 8 and rotate, pumping pipe 8 is slowly taken out boundary layer liquid under to the observation of visor 10, then heparin sodium aqua enters next flow process.
Claims (2)
1. be used for carrying out the streamline of heparin sodium purification, comprise reactor, it is characterized in that: also comprise butterfly centrifugal machine, tubular-bowl centrifuge, have reactor and the closed dull and stereotyped whizzer of still waist pumping device, described reactor bottom is connected with the butterfly centrifugal machine by pipeline, described butterfly centrifugal machine is connected with tubular-bowl centrifuge by pipeline, described tubular-bowl centrifuge is connected with the reactor with still waist pumping device by pipeline, and described reactor bottom with still waist pumping device is connected with closed dull and stereotyped whizzer by pipeline.
2. the streamline be used to carrying out heparin sodium purification according to claim 1, it is characterized in that: in the reactor with still waist pumping device, its still waist pumping device is fixed in the side of reactor, described still waist pumping device comprises visor, handle, hand lever and pumping pipe, described visor is located at the reactor side, described handle is individually fixed in top and the middle and lower part of hand lever, and described hand lever is flexibly connected with the conical gear that is fixed on the pumping pipe by the conical gear of its bottom.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 201220521292 CN202808659U (en) | 2012-10-12 | 2012-10-12 | Assembly line for heparin sodium purification |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 201220521292 CN202808659U (en) | 2012-10-12 | 2012-10-12 | Assembly line for heparin sodium purification |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN202808659U true CN202808659U (en) | 2013-03-20 |
Family
ID=47867576
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 201220521292 Expired - Fee Related CN202808659U (en) | 2012-10-12 | 2012-10-12 | Assembly line for heparin sodium purification |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN202808659U (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106943770A (en) * | 2017-05-05 | 2017-07-14 | 章守艳 | Pig duodenum extract extraction element |
-
2012
- 2012-10-12 CN CN 201220521292 patent/CN202808659U/en not_active Expired - Fee Related
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106943770A (en) * | 2017-05-05 | 2017-07-14 | 章守艳 | Pig duodenum extract extraction element |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20130320 Termination date: 20151012 |
|
| EXPY | Termination of patent right or utility model |