CN202794170U - Constant-temperature system and biochemical analyzer - Google Patents
Constant-temperature system and biochemical analyzer Download PDFInfo
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- CN202794170U CN202794170U CN 201220162993 CN201220162993U CN202794170U CN 202794170 U CN202794170 U CN 202794170U CN 201220162993 CN201220162993 CN 201220162993 CN 201220162993 U CN201220162993 U CN 201220162993U CN 202794170 U CN202794170 U CN 202794170U
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Abstract
The utility model relates to the technical field of biochemical analysis, and discloses a constant-temperature system which comprises a constant-temperature trough, a reaction disc, a reaction container and a heating element, wherein the reaction disc is arranged in the constant-temperature trough, the reaction container is used for accommodating reaction liquid required to be subjected to biochemical reaction, the heating element is adhered to the external surface of the constant-temperature trough, the reaction container is arranged in the reaction disc, the external surface of the reaction container is wrapped with the reaction disc, and a first gap is formed between the constant-temperature trough and the reaction disc. Compared with the prior art, the constant-temperature system disclosed by the utility model integrates the advantages of a solid direct-heating mode and a fixed constant-temperature liquid mode, and no liquid is required to be used as a working medium, so that the participation of motor elements such as power cycle devices and the like is also not required, therefore, the power loss can be saved, and the characteristics of energy saving and environmental protection can be embodied; and the constant-temperature system is relatively strong in operating reliability, truly embodies the advantages of energy saving, environmental protection, no noise, long service life, stable operation and the like, and can provide a constant-temperature environment.
Description
Technical field
The utility model relates to the technical field of biochemical analysis, relates in particular to the Biochemical Analyzer that constant temperature system is provided and comprises this constant temperature system.
Background technology
The IVD such as Biochemical Analyzer (In Vitro Diagnostic, in-vitro diagnosis) equipment is in the process of work, an isoperibol need to be provided for the biochemical reaction that occurs in it, incubate bath so that biochemical reaction vessel (such as cuvette) is realized constant temperature.Along with the progress of science and technology and to improving constantly that test result requires, requirement to isoperibol is also more and more higher, in the current requirement, the temperature that not only needs to guarantee constant temperature accurately, stable, also need the advantages such as energy-conserving and environment-protective, noiselessness, non-maintaining and long-life.
Constant temperature means of the prior art have several forms such as water-bath (oil bath), air bath, solid directly-heated and solid constant temperature liquid, and are specific as follows:
1), water-bath (oil bath).This constant temperature system at first needs to keep the constant temperature of liquid, then use the liquid of constant temperature that biochemical reaction container (such as cuvette) realization constant temperature is incubated bath, it needs periodic maintenance, and cycle power device (such as pump etc.) must be set in the system, rely on cycle power device to realize circulating of isothermal liquid.In fact, the power consumption of cycle power device only is the resistance loss when offsetting liquid flow, be not converted into reaction vessel and incubate and bathe needed net horsepower, so this part power consumption is " unnecessary " or " useless ", that is to say that this constant temperature system is not energy-conservation; Water or wet goods are as the actuating medium of water-bath in addition.There is the risk of revealing, not environmental protection;
2), air bath.It is close with water-bath, and difference is that the medium of constant temperature has become gas by liquid.Although it has overcome the shortcoming that water-bath need to be safeguarded, because the air thermal capacitance is less, the less stable of this constant temperature system 1; In addition, also need to arrange cycle power device (such as fan etc.) in this constant temperature system and promote flowing of gas, and the power consumption that consumes of Circulated power system bathing for the needed power with respect to incubating, also is " unnecessary ", therefore not energy-conservation;
3), solid directly-heated temperature control mode.This constant temperature system then is that direct solid to high thermal conductivity heats to guarantee constant temperature, and this constant temperature solid directly contacts with the constant temperature of realization response container with the biochemical reaction container and incubates bath.The defective that this kind temperature control system exists is: PERIODIC INTERFERENCE to external world (such as automatic cleaning thermal shock) sensitivity, temperature stability is slightly poor.In addition, this constant temperature system often can use the signal transmission structures such as conducting slip ring, its complex structure, and because the existence of moving component, affected the reliability of whole constant temperature system.
4), solid constant temperature liquid temperature control mode.This constant temperature system is the heating liquid solid wall surface (such as calibration cell) that adopts constant temperature, and the outer wrap of reaction vessel has the metal material (such as reaction tray) of high thermal conductivity, has certain clearance between two solids.Heat by isothermal liquid pass to the wall of constant temperature, sequentially via clearance, metal material, be passed at last reaction vessel, realize that constant temperature incubates bath.The defective that this constant temperature system exists is: needs to increase cycle power device (such as pump etc.) in this constant temperature system, is used for promoting circulating of liquid, and therefore, energy-conservation not; And owing to have moving component in this constant temperature system, affected the reliability of whole system simultaneously.
The utility model content
The purpose of this utility model is to provide constant temperature system, is intended to solve constant temperature system of the prior art and has not energy-conservation, not environmental protection and the lower problem of reliability.
The utility model is to realize like this, constant temperature system, comprise calibration cell, place described calibration cell reaction tray, be used for device and need the reaction vessel of reactant liquor of biochemical reaction and the heating element that is attached at described calibration cell outside surface, described reaction vessel places described reaction tray, and outside surface is wrapped up by described reaction tray, has the first gap between described calibration cell and the described reaction tray.
Further, also comprise the control element that to control the running of described heating element and can detect described calibration cell temperature and institute's detection information be passed to the temperature sensor of described control element, described temperature sensor is electrically connected at described control element, and place described calibration cell, described heating element is electrically connected at described control element.
Further, also comprise the thermal insulation protection shell that has enclosure space in it, described calibration cell, heating element, reaction tray and reaction vessel place the enclosure space of described thermal insulation protection shell.
Further; described thermal insulation protection shell comprises the insulation can with the 3rd cavity volume and places on the described insulation can and can seal the insulation cover of described the 3rd cavity volume opening that described calibration cell, heating element, reaction tray and reaction vessel place described the 3rd cavity volume.
Further, be provided with between described calibration cell and the described reaction tray and can increase the embedded structure that both heat are changed area.
Further, described embedded structure comprise raised line or the groove that is formed at described calibration cell inwall and be formed at described reaction tray outside surface and can with groove or the raised line of described raised line or groove corresponding matching, have the second gap between described raised line and the described groove.
Further, be provided with a plurality of described reaction tray in the described calibration cell, and be provided with the isolation raised line between each adjacent described reaction tray, described isolation raised line is formed at described calibration cell inwall.
The utility model also provides Biochemical Analyzer, and it comprises above-mentioned constant temperature system.
Compared with prior art, constant temperature system of the present utility model combines solid directly-heated mode and the fixing advantage of constant temperature liquid mode, it does not need liquid as actuating medium, thereby also do not need the participation of the motor elements such as power circulating device, but the saving power loss, the characteristics of embodiment energy-saving and environmental protection, and the reliability of this constant temperature system work is stronger, really embodied energy-saving and environmental protection, noiselessness, life-span length and steady operation and other merits, the environment of a constant temperature can be provided.
Description of drawings
Fig. 1 is the cross-sectional schematic one of the constant temperature system that provides of the utility model embodiment one;
Fig. 2 is the schematic perspective view of the constant temperature system that provides of the utility model embodiment one;
Fig. 3 is the cross-sectional schematic two of the constant temperature system that provides of the utility model embodiment one;
Fig. 4 is the cross-sectional schematic three of the constant temperature system that provides of the utility model embodiment one;
Fig. 5 is the cross-sectional schematic four of the constant temperature system that provides of the utility model embodiment one;
Fig. 6 is the cross-sectional schematic five of the constant temperature system that provides of the utility model embodiment one;
Fig. 7 is the cross-sectional schematic six of the constant temperature system that provides of the utility model embodiment one;
Fig. 8 is the cross-sectional schematic seven of the constant temperature system that provides of the utility model embodiment one;
Fig. 9 is the cross-sectional schematic of the constant temperature system that provides of the utility model embodiment two;
Figure 10 is the cross-sectional schematic of the constant temperature system that provides of the utility model embodiment three;
Figure 11 is the cross-sectional schematic of the constant temperature system that provides of the utility model embodiment four;
Figure 12 is the schematic layout pattern of the Biochemical Analyzer that provides of the utility model embodiment.
Embodiment
In order to make the purpose of this utility model, technical scheme and advantage clearer, below in conjunction with drawings and Examples, the utility model is further elaborated.Should be appreciated that specific embodiment described herein only in order to explaining the utility model, and be not used in restriction the utility model.
The utility model provides constant temperature system, comprise calibration cell, place described calibration cell reaction tray, be used for device and need the reaction vessel of reactant liquor of biochemical reaction and the heating element that is attached at described calibration cell outside surface, described reaction vessel places described reaction tray, and outside surface is wrapped up by described reaction tray, has the first gap between described calibration cell and the described reaction tray.
Constant temperature system in the utility model utilizes heating element directly calibration cell to be heated, thereby can avoid using liquid-working-medium and power circulating device etc., have energy-saving and environmental protection, noiselessness, life-span length and steady operation and other merits, the environment of a constant temperature can be provided, guarantee that the constant temperature of reactant liquor is incubated bath.
Below in conjunction with concrete accompanying drawing realization of the present utility model is described in detail.
Embodiment one
Shown in Fig. 1～8, for the utility model provides a preferred embodiment.
The constant temperature system 1 that present embodiment provides for the environment that a constant temperature is provided to biochemical reaction, is incubated the bath state so that the reagent in the reaction vessel 16 is in constant temperature, guarantees the accuracy of test structure.
Above-mentioned constant temperature system 1 comprises calibration cell 13, the reaction tray 15 that places the first cavity volume of calibration cell 13 with first cavity volume, place the reaction vessel 16 of reaction tray 15 and be sticked at the heating element 14 of calibration cell 13 outside surfaces.The first cavity volume of calibration cell 13 is communicated with its upper end, thereby forms the opening of this calibration cell 13; Reaction tray 15 is placed in the first cavity volume of calibration cell 13 by this opening, and has the first gap 18 between the inwall of the outside surface of reaction tray 15 and the first cavity volume, certainly, the size in the first gap 18 can design according to actual conditions, generally speaking, this first gap 18 is less then better, it both can guarantee that reaction tray 15 can move in the first cavity volume of calibration cell 13, and can guarantee heat exchange thermal resistance less between calibration cell 13 and the reaction tray 15, thereby the heat transmission of heating element 14 is provided; Be provided with the second cavity volume (not marking among the figure) in the reaction tray 15,16 devices of reaction vessel are in this second cavity volume, and its outside surface is wrapped up by the inwall of the second cavity volume, thereby reduce the heat exchange thermal resistance between reaction tray 15 and the reaction vessel 16, also guarantee simultaneously the consistance of whole system temperature and the stability of temperature; Can install the reactant liquor that needs to occur biochemical reaction in the reaction vessel 16, thereby when reaction vessel 16 was in constant temperature shape body, the reactant liquor in it also was in temperature constant state, thereby the assurance reactant liquor can be incubated bath under the state of constant temperature.
The heat transfer process of above-mentioned constant temperature system 1 is such: the heat that heating element 14 sends sequentially by the first gap 18, reaction tray 15 and reactor transmission between calibration cell 13, calibration cell 13 and the reaction tray 15, is delivered to the reactant liquor of device in reactor at last.
Utilize above-mentioned constant temperature system 1 that the environment of a constant temperature can be provided to reactant liquor, this constant temperature system 1 combines solid directly-heated mode and the fixing advantage of constant temperature liquid mode, it utilizes heating element 14 directly to calibration cell 13 heating, thereby can omit liquid-working-medium, and do not need power circulating device yet, can save unnecessary power attenuation, embody the energy-saving and environmental protection advantage, and do not need the participation of motor element in this constant temperature system 1, can greatly improve the reliability of this constant temperature system 1.This constant temperature system 1 has really embodied energy-saving and environmental protection, noiselessness, life-span length and steady operation and other merits under the prerequisite that guarantees the temperature accuracy.
The material manufacturing that reaction tray 15 in above-mentioned is generally high thermal conductivity, high heat capacity forms, thereby can guarantee the high-level efficiency that heat transmits; 13 of calibration cells are made for the material of high thermal conductivity; Heating element 14 can adopt the well heater of number of different types, in the present embodiment, for the temperature consistance of this constant temperature system 1 is provided, heating element 14 adopts the thin film heater that cooperates with calibration cell 13 external surface shape, like this, also can guarantee fitting tightly of this heating element 14 and calibration cell 13 outside surfaces, certainly, thin film heater is not unique selection, according to the needs of actual conditions, can adopt the well heater of other types yet.
For temperature that can perception calibration cell 13, thereby reach high-precision temperature control, this constant temperature system 1 also comprises temperature sensor 12 and control element (not marking among the figure), this temperature sensor 12 is installed on the sidewall of calibration cell 13, it can be used for the in real time temperature of induction calibration cell 13, and be electrically connected on the control element, heating element 14 in above-mentioned also is electrically connected on this control element, temperature sensor 12 can pass to control element in real time with the information that detects, control element can be not destroyed with the temperature constant state that guarantees high constant temperature system 1 according to the control of the information realization that receives to heating element 14.
In the present embodiment; constant temperature system 1 also comprises thermal insulation protection shell 11; this thermal insulation protection shell 11 is enclosed in outside the whole calibration cell 13; and heating element 14 also is in this thermal insulation protection shell 11; its this thermal insulation protection shell 11 is the structure of a sealing; its shell as whole constant temperature system 1 exists; other all parts all are closed within this thermal insulation protection shell 11; like this; both can prevent heat leak; that improves reactant liquor incubates bath efficient, and also energy-saving and environmental protection, avoids heat leak that environment is impacted.
Particularly, above-mentioned thermal insulation protection shell 11 comprises the insulation can 112 with the 3rd cavity volume and places on this insulation can 112 and can seal the insulation cover 111 of the 3rd cavity volume.Calibration cell 13 and heating element 14 are placed in this insulation can 112 together, and the inwall of insulation can 112 is adjacent on the outside surface of calibration cell 13,14 bottoms that place the 3rd cavity volume of heating element, and be adjacent to respectively the inwall of the 3rd cavity volume and the outside surface of calibration cell 13; Insulation cover 111 places the opening part of the top of insulation can 112, and can seal the opening of the 3rd cavity volume, thereby so that calibration cell 13 and heating element 14 are in the environment of a sealing, avoids occurring the phenomenon that heat is revealed.
Owing to be to come transferring heat by the first gap 18 between it between calibration cell 13 and the reaction tray 15, efficient and the increase coefficient of heat transfer for the heat that increases is between the two transmitted are provided with the embedded structure 19 that can increase heat interchanging area between calibration cell 13 and the reaction tray 15 between calibration cell 13 and the reaction tray 15.
Particularly, above-mentioned embedded structure 19 comprises the groove 191 that forms on the raised line 192 that forms on the calibration cell 13 first cavity volume inwalls and the reaction tray 15, raised line 192 is placed in the groove 191, and there is the second gap with the surface of groove 191, like this, both guaranteed directly not contact between calibration cell 13 and the reaction tray 15, there are the characteristics in gap in both, and the structure by raised line 192 and groove 191 can increase the heat interchanging area between calibration cell 13 and the reaction tray 15 greatly.
Certainly the raised line in above-mentioned also can be formed on the outside surface of reaction tray 15, and groove is arranged on the inwall of calibration cell 13 first cavity volumes, and concrete the setting decided by actual conditions.
In addition, the number of raised line 192 and groove 191 also can be decided according to actual conditions, is not limited to concrete number.
As shown in Figure 3, embedded structure 19 can be arranged on the bottom of calibration cell 13 first cavity volumes; As shown in Figure 4,19 both sides that are arranged on calibration cell 13 of embedded structure; Such as Fig. 5 and shown in Figure 6,19 of embedded structures are arranged on respectively on the side of calibration cell 13.Certainly, the concrete setting of embedded structure 19 is decided by actual conditions.
In above-mentioned constant temperature system 1, can place a reaction tray 15 in the calibration cell 13, certainly, also can place a plurality of reaction tray 15, when needs were placed a plurality of reaction tray 15, the size that only need to enlarge accordingly calibration cell 13 then could.
Such as Fig. 7 and shown in Figure 8, it is respectively the constant temperature system 1 that comprises two and three reaction tray 15.Comprised a plurality of reaction tray 15 in constant temperature system 1, formed isolation raised line 192 on the inwall of the first cavity volume of calibration cell 13, isolation raised line 192 places between the adjacent reaction tray 15, is used for reaction tray 15 is carried out placement positioning.
In the present embodiment, heating element 14 is sticked on the bottom of calibration cell 13, that is to say that heat is that bottom from calibration cell 13 upwards is passed to the reaction tray 15.
Embodiment two
As shown in Figure 9, a preferred embodiment that provides for the utility model.
The difference of present embodiment and embodiment one is: heating element 14 is to be sticked on a side of calibration cell 13, that is to say that heat is that a side from calibration cell 13 is passed to the reaction tray 15.
Embodiment three
Such as Figure 10, a preferred embodiment that provides for the utility model.
The difference of present embodiment and embodiment two is: heating element 14 is to be sticked on the opposite side of calibration cell 13, that is to say that heat is that opposite side from calibration cell 13 is passed to the reaction tray 15.
Embodiment four
As shown in figure 11, a preferred embodiment that provides for the utility model.
The difference of present embodiment and embodiment one is: heating element 14 is sticked respectively on the bottom and lateral surface of calibration cell 13, that is to say that heat is that whole outside surface from calibration cell 13 is passed to the reaction tray 15.
The utility model also provides Biochemical Analyzer, it has comprised the constant temperature system 1 in above-described embodiment, as shown in figure 12, be the schematic layout pattern of Biochemical Analyzer, on the table top mainly by reagent disc 2, sample disk 3, reaction tray 15, reagent needles 4, specimen needle 5, puddler 6 and automatically clean several parts and consist of.Carry reaction vessel 16 on the reaction tray 15.During work, wiper mechanism is implemented to clean to the reaction vessel 16 on the reaction tray 15.Cleaning reagent pin 4 is drawn reagent from reagent disc 2 and is injected reaction vessel 16, and specimen needle 5 is drawn sample to be tested from sample disk 3 and injected reaction vessel 16.Reagent in the reaction vessel 16, sample are incubated in reaction tray 15 and are bathed reaction through after fully mixing.Data acquisition system (DAS) record course of reaction, thus test result obtained by computational analysis, finish once test.Wherein 1 of the constant temperature system in above-described embodiment is for the reactant liquor in the reaction vessel 16 provides isoperibol, for the biochemical reaction of reactant liquor provides suitable, accurate, the stable bath environment of incubating.
The above only is preferred embodiment of the present utility model; not in order to limit the utility model; all any modifications of within spirit of the present utility model and principle, doing, be equal to and replace and improvement etc., all should be included within the protection domain of the present utility model.
Claims (8)
1. constant temperature system, it is characterized in that, comprise calibration cell, place described calibration cell reaction tray, be used for device and need the reaction vessel of reactant liquor of biochemical reaction and the heating element that is attached at described calibration cell outside surface, described reaction vessel places described reaction tray, and outside surface is wrapped up by described reaction tray, has the first gap between described calibration cell and the described reaction tray.
2. constant temperature system as claimed in claim 1, it is characterized in that, also comprise the control element that to control the running of described heating element and can detect described calibration cell temperature and institute's detection information be passed to the temperature sensor of described control element, described temperature sensor is electrically connected at described control element, and place described calibration cell, described heating element is electrically connected at described control element.
3. constant temperature system as claimed in claim 1 or 2 is characterized in that, also comprises the thermal insulation protection shell that has enclosure space in it, and described calibration cell, heating element, reaction tray and reaction vessel place the enclosure space of described thermal insulation protection shell.
4. constant temperature system as claimed in claim 3; it is characterized in that; described thermal insulation protection shell comprises the insulation can with the 3rd cavity volume and places on the described insulation can and can seal the insulation cover of described the 3rd cavity volume opening that described calibration cell, heating element, reaction tray and reaction vessel place described the 3rd cavity volume.
5. constant temperature system as claimed in claim 1 or 2 is characterized in that, being provided with between described calibration cell and the described reaction tray to increase the embedded structure that both heat are changed area.
6. constant temperature system as claimed in claim 5, it is characterized in that, described embedded structure comprise raised line or the groove that is formed at described calibration cell inwall and be formed at described reaction tray outside surface and can with groove or the raised line of described raised line or groove corresponding matching, have the second gap between described raised line and the described groove.
7. constant temperature system as claimed in claim 1 or 2 is characterized in that, is provided with a plurality of described reaction tray in the described calibration cell, and is provided with the isolation raised line between each adjacent described reaction tray, and described isolation raised line is formed at described calibration cell inwall.
8. Biochemical Analyzer is characterized in that, comprises the described constant temperature system of any one in the claim 1～7.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 201220162993 CN202794170U (en) | 2012-04-17 | 2012-04-17 | Constant-temperature system and biochemical analyzer |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 201220162993 CN202794170U (en) | 2012-04-17 | 2012-04-17 | Constant-temperature system and biochemical analyzer |
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| CN202794170U true CN202794170U (en) | 2013-03-13 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN 201220162993 Expired - Lifetime CN202794170U (en) | 2012-04-17 | 2012-04-17 | Constant-temperature system and biochemical analyzer |
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Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105137105A (en) * | 2015-08-28 | 2015-12-09 | 深圳市锦瑞电子有限公司 | Miniature biochemical analyzer |
| CN105911299A (en) * | 2016-05-12 | 2016-08-31 | 利多(香港)有限公司 | Liquid heater for analyzer |
| CN107342140A (en) * | 2017-07-28 | 2017-11-10 | 清华大学深圳研究生院 | A kind of method for making rare earth barium copper oxide superconducting film and constant temperature dipping system |
| EP3457142A4 (en) * | 2016-05-12 | 2020-01-01 | Leadway (HK) Limited | Thermal insulation casing for analyzer |
-
2012
- 2012-04-17 CN CN 201220162993 patent/CN202794170U/en not_active Expired - Lifetime
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105137105A (en) * | 2015-08-28 | 2015-12-09 | 深圳市锦瑞电子有限公司 | Miniature biochemical analyzer |
| CN105911299A (en) * | 2016-05-12 | 2016-08-31 | 利多(香港)有限公司 | Liquid heater for analyzer |
| EP3457142A4 (en) * | 2016-05-12 | 2020-01-01 | Leadway (HK) Limited | Thermal insulation casing for analyzer |
| CN107342140A (en) * | 2017-07-28 | 2017-11-10 | 清华大学深圳研究生院 | A kind of method for making rare earth barium copper oxide superconducting film and constant temperature dipping system |
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| GR01 | Patent grant | ||
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Granted publication date: 20130313 |