CN202699376U - Sensing and stimulating system of skin temperature - Google Patents

Sensing and stimulating system of skin temperature Download PDF

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Publication number
CN202699376U
CN202699376U CN201220143245.6U CN201220143245U CN202699376U CN 202699376 U CN202699376 U CN 202699376U CN 201220143245 U CN201220143245 U CN 201220143245U CN 202699376 U CN202699376 U CN 202699376U
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China
Prior art keywords
circuit
water
skin temperature
head
cooling
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Expired - Lifetime
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CN201220143245.6U
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Chinese (zh)
Inventor
秦伟
刘鹏
朱振营
胡凯
何嘉全
田捷
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Xidian University
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Xidian University
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Abstract

The utility model discloses a sensing and stimulating system of skin temperature. The sensing and stimulating system of the skin temperature mainly solves the problem that an existing laser stimulating device cannot carry out refrigeration, and is complex in operation and high in cost in the nuclear-magnetic environment. The sensing and stimulating system of the skin temperature comprises a cold-hot stimulus head (1), a protecting net (2), a heat radiating water tank (3), a water pump (4), a water storage tank (5), an inlaid type control module (6) and an upper computer (7). The cold-hot stimulus head (1), the heat radiating water tank (3), the water pump (4) and the water storage tank (5) are connected with each other in sequence through water pipes, and therefore a water circulating system is formed. The cold-hot stimulus head (1) is connected with the upper computer (7) through the inlaid type control module (6). The inlaid type control module (6) controls the cold-hot stimulus head (1) to stimulate human body skin according to stimulus temperature set by the upper computer (7), the values of the actual stimulus temperature and the painful feeling are transmitted to the upper computer (7) to store and display through the inlaid type control module (6). The sensing and stimulating system of the skin temperature has the advantages of being easy to operate, and safe to use, and can be applied to the study of the painful feeling and the evaluation of analgesic effects in the nuclear-magnetic environment.

Description

Skin temperature sensory stimuli system
Technical field
This utility model belongs to technical field of medical instruments, particularly the instrument of a kind of researching human body threshold of pain and threshold of pain tolerance.Can be used for pain perception research, analgesic effect evaluation, medical personnel in normal and the strong magnetic field circumstance to pain disease patient's auxiliary diagnosis and treatment.
Background technology
The whole world about 5,500,000 people every day stand the torment of cancer pain at present, and China has the pain patients more than 100,000,000 at least.Pain, the misery that this human beings is original has become global pharmaceuticals industry questions of common interest.Scientific research institution is also more and more to the evaluation study of pain perception research and analgesic effect.
The research of pain is focus and the difficulties in neuroscience field, and along with the progress of Imaging Technology, the research of pain has welcome unprecedented opportunities.But based on the pain research of Functional magnetic resonance imaging, accurate, controlled pain stimulation pattern need to be arranged, and can with the experimental facilities of nuclear-magnetism environmental compatible.Can only adopt at present laser stimulation equipment as the pain stimulation equipment of Functional magnetic resonance imaging.This laser stimulation equipment has the following disadvantages:
1) thermostimulation can only be produced but cold stimulation can not be produced;
2) complicated operation, volume are greatly, safety is not high, cost is high;
3) complexity of communicating by letter with host computer, data are open.
The utility model content
The purpose of this utility model is the deficiency for above-mentioned laser stimulation equipment, proposing a kind ofly can provide caloric stimulation, simple to operate, safe, cold and hot pain stimulation instrument that cost is low, with the caloric stimulation pattern of setting according to the experimenter in the nuclear-magnetism environment that is implemented in high-intensity magnetic field, carry out pain stimulation, and Current Temperatures data and pain perception are real-time transmitted in the host computer.
For achieving the above object, this utility model comprises caloric stimulation head 1, catch net 2, cooling water tank 3, water pump 4, water-storing tank 5, embedded type control module 6 and host computer 7; Caloric stimulation head 1, cooling water tank 3, water pump 4 and water-storing tank 5 link to each other successively by water pipe, form water circulation system; Caloric stimulation head 1 is connected with host computer 7 by embedded type control module 6;
Described caloric stimulation head 1 comprises conducting strip 11, cooling piece 13, water-cooling head 14, shell 15, binder 17, button 18 and heat insulating mattress 19; The one side of cooling piece 13 is pasted conducting strip 11, and another side is pasted water-cooling head 14; Cooling piece 13 and water-cooling head 14 place in the cavity of conducting strip 11 and shell 15 compositions; Heat insulating mattress 19 is pasted the front at shell 15; Binder 17 is fixed on the back side of shell 15 by button 18; Conducting strip 11 places the stimulation point on the human body skin;
Described embedded type control module 6, comprise embedded processing circuit, D A change-over circuit, power amplification circuit, electric current go to circuit, current-limiting protection circuit, bridge circuit, differential amplifier circuit, A D change-over circuit and marking circuit; This embedded processing circuit is according to the stimulation temperature that arranges in the host computer 7, produce the relevant voltage digital signal, input in the D A change-over circuit and convert analogue signal to, after being input to the electric current go to circuit after amplifying through power amplification circuit again, behind current-limiting protection circuit, be input to again in the cooling piece 13, intensification or the cooling of control cooling piece 13, and then control conducting strip 11 variations in temperature; The resistance value that this bridge circuit will be pasted thin film platinum resistance thermometer sensor, 12 between conducting strip 11 and cooling piece 13 converts magnitude of voltage to, be transferred in the A D change-over circuit and convert digital signal to, be transferred to again in the embedded processing circuit, current temperature value is compared with the set temperature value, judging increases or reduces voltage, and the embedded processing circuit is transferred to current temperature value to store in the host computer 7 and shows simultaneously; The subjects gives a mark according to the slide block that current pain moves on the slide rheostat, this marking circuit changes into magnitude of voltage with the resistance of slide rheostat, through A the D change-over circuit be connected to the embedded processing circuit, the embedded processing circuit is transferred in the host computer 7 storage to the marking value by serial ports and shows.
Said system is characterized in that water-cooling head 14 comprises water inlet, outlet and internal channel 16; Internal channel 16 is the M shape, and is linked to be path with water inlet and the outlet of water-cooling head 14 the same sides.
Said system is characterized in that conducting strip 11 is that the thickness that adopts the red copper material to make is the convex shape thin slice of 8mm, and is two-layer about being divided into, and the area on upper strata is 1/2nd of lower floor's area; Cover has three-back-shaped heat insulating mattress 19 around the upper strata.
Said system it is characterized in that shell 15 is processed by 3mm fine copper thin plate, and the center at the back side is welded with fine copper matter button 18.
Said system is characterized in that bridge circuit is connected to form by thin film platinum resistance thermometer sensor, 12 and three substitutional resistances.
Said system is characterized in that connecting the water pipe of caloric stimulation head 1, the lead-in wire of thin film platinum resistance thermometer sensor, 12 and the lead-in wire of cooling piece 13 and all is placed in the catch net 12.
Said system, the circuit that it is characterized in that giving a mark comprises slide rheostat, divider resistance and the screening can of being made by pure copper material; Slide block is housed on the screening can and indicates the slider track scale, slide block connects slide rheostat.
Said system is characterized in that the embedded processing circuit, comprises STM32 processor, jtag interface circuit, real time clock circuit and serial communication circuit; Jtag interface circuit, real time clock circuit are connected with the STM32 processor respectively, and the STM32 processor links to each other with host computer 7 by serial communication circuit.
Said system is characterized in that the electric current go to circuit, comprises common collector amplifying circuit and relay; The input of common collector amplifying circuit connects the STM32 processor, and output connects relay.
Said system is characterized in that current-limiting protection circuit is made of automatic recovery fuse and resistance series connection.
The utlity model has following advantage:
1, this utility model since with the component assemble of caloric stimulation head in copper housing, not only volume is little, handled easily, and guarantees the normal use of caloric stimulation head in the nuclear-magnetism environment.This utility model not only makes the step evolution that heats up or lower the temperature good owing to adopt semiconductor chilling plate heat production or refrigeration, and safe.
2, this utility model adopts water cycle to keep the stable of water-cooling head temperature, and then keeps the underlaying surface temperature of cooling piece to keep stable, guarantees that the caloric stimulation head works for a long time.
3, embedded type control module of the present utility model adopts degenerative mode to control the temperature of cooling piece, and making stimulates temperature more accurate.This utility model can prevent effectively that fault from causing overheated or supercool scald or the cold injury that the subjects is produced of cooling piece owing to be provided with current-limiting protection circuit.
4, this utility model stimulates temperature owing to adopt host computer to set, the experimenter can set concrete stimulation temperature according to actual needs in host computer, and can stimulating temperature and subjects's pain perception to be real-time transmitted to storage demonstration in the host computer, be convenient to experimental analysis.
Description of drawings
Fig. 1 is overall structure sketch map of the present utility model;
Fig. 2 is the caloric stimulation header structure sketch map in this utility model;
Fig. 3 is the embedded type control module schematic diagram in this utility model.
The specific embodiment
Below in conjunction with accompanying drawing enforcement principle of the present utility model and use are described in detail.
With reference to Fig. 1, this utility model system comprises caloric stimulation head 1, catch net 2, cooling water tank 3, water pump 4, water-storing tank 5, embedded type control module 6 and host computer 7; Caloric stimulation head 1, cooling water tank 3, water pump 4 and water-storing tank 5 link to each other successively by water pipe, form water circulation system; Caloric stimulation head 1 is connected with host computer 7 by embedded type control module 6.The water that caloric stimulation head 1 flows out flows into water-storing tank after the cooling first again in cooling water tank, reduce the variation of water-storing tank temperature, keeps caloric stimulation head 1 and flows into the stable of coolant-temperature gage, guarantees for a long time normal operation of caloric stimulation head 1.
Embedded type control module 6 stimulates according to 1 pair of human body skin of stimulation temperature control caloric stimulation head that host computer 7 arranges, the score value of this practical stimulation temperature and pain perception is transferred in the host computer 7 storage through embedded type control module 6 again and shows, for the experimenter according to the score value of this practical stimulation temperature and pain perception to the pain perception research of human body and the analgesic effect evaluation of medicine.
Caloric stimulation head 1 in the employing 1m long water pipe connection nuclear-magnetism environment and other equipment in the water circulation system have reduced the parts that need the strong magnetic signal of shielding effectively; The water pipe, cooling piece 13 lead-in wires, thin film platinum resistance thermometer sensor, 12 lead-in wires that connect water-cooling head 14 all place the inside of catch net 2, form an integral body, handled easily;
With reference to Fig. 2, caloric stimulation head 1, it comprises conducting strip 11, cooling piece 13, water-cooling head 14, shell 15, binder 17, button 18 and heat insulating mattress 19; It is the convex shape thin slice of 8mm that conducting strip 11 becomes thickness by red copper materials processing, be divided into two-layer up and down, the upper strata is the square sheet of length of side 28mm, lower floor is the square sheet of length of side 40mm, the area on upper strata is 1/2nd of lower floor's area, lower floor utilizes heat-conducting silicone grease to paste on semiconductor chilling plate 13, and accompanies thin film platinum resistance thermometer sensor, 12 between conducting strip 11 and the cooling piece 13; Three-back-shaped rubber heat insulating 19 is enclosed within the outside on conducting strip 11 upper stratas, and the height of rubber heat insulating is no more than the height on conducting strip 11 upper stratas, and pastes on the shell 15 by 3mm fine copper thin plate processing factory, to prevent shell 15 and contact skin, affects effect of stimulation.Binder 17 is fixed on the center, the back side of fine copper matter shell 15 by fine copper matter button 18, and binder 17 plays the fixedly effect of caloric stimulation head 1, and caloric stimulation head 1 rocks when reducing work.Shell 15 forms the cavity that seals with conducting strip 11, can effectively shield the strong magnetic signal in the external environment condition, thin film platinum resistance thermometer sensor, 12 and cooling piece 13 that protection is inner.
This cooling piece 13 is that the heating of cooling piece 13 and the two kinds of functions of freezing are controlled by forward and reverse current according to the focus semiconductor refrigerating assembly of the former reason N-type semiconductor of peltier effect and P-type semiconductor composition; And work the time does not need cold-producing medium, does not have rotary part, has pollution-free, noiseless, long advantage of life-span.The underrun heat-conducting silicone grease of cooling piece 13 is pasted on fine copper matter water-cooling head 14, and there is M shape raceway groove 16 water-cooling head 14 inside, and M shape raceway groove 16 can increase the water capacity of water-cooling head 14, and then improves the heat exchanger effectiveness of water-cooling head 14; Water inlet and outlet place the same side of water-cooling head 14; One end of raceway groove 16 connects water inlet, and the other end connects outlet, forms path.
With reference to Fig. 3, embedded type control module F, it comprise embedded processing circuit, D A change-over circuit, power amplification circuit, electric current go to circuit, current-limiting protection circuit, bridge circuit, differential amplifier circuit, A D change-over circuit and marking circuit.Wherein:
The embedded Control circuit comprises STM32 processor, jtag interface circuit, real time clock circuit and serial communication circuit; The STM32 processor is based on the flush bonding processor of the Cortex-M3 of ARM company kernel framework; Jtag interface circuit, real time clock circuit are connected with the STM32 processor respectively, and the STM32 processor links to each other with host computer 7 by serial communication circuit; The embedded Control circuit respectively with D A change-over circuit, electric current go to circuit and A the D change-over circuit link to each other.
D the A change-over circuit, formed by 12 figure place mould conversion chips and peripheral circuit, D the A change-over circuit connect power amplification circuit.
Power amplification circuit is made of large current mode field effect transistor power amplifier and peripheral circuit, and power amplification circuit connects the movable contact of electric current go to circuit repeat circuit.The electric current go to circuit is made of common collector amplifying circuit and relay, and the input of common collector amplifying circuit connects the STM32 processor, and output connects relay; Four stationary contact interconnections of relay form two outfans, and two outfans are connected with current-limiting protection circuit.Current-limiting protection circuit is made of automatic recovery fuse and resistance series connection.Automatic recovery fuse be a kind of employing macromolecule organic polymer at high pressure, high temperature, under the condition of vulcanization reaction after the admixture particulate materials, the overcurrent Electronic Protection element that processes through special process.
A the D change-over circuit adopt 12 one by one type transformational structures relatively, be connected with the circuit of being connected with differential amplifier circuit respectively; Differential amplifier circuit connects bridge circuit, and bridge circuit is connected to form by thin film platinum resistance thermometer sensor, 2 and three substitutional resistances.Thin film platinum resistance thermometer sensor, 2 is to utilize the resistance value variation with temperature of platinum filament and the principle that changes, and adopts the advanced high-tech approaches such as laser spraying plating, microphotograph, offset printing photoetching, and resistance is made the temperature sensor of fine setting with digital finishing mode; Have the advantages such as volume is tiny, response time is fast, precision is high, good stability.
The marking circuit comprises slide rheostat, divider resistance and the screening can of being made by pure copper material; Slide block is housed on the screening can and indicates the slider track scale, slide block connects slide rheostat; The subjects can give a mark to pain by moving slider;
Operation principle of the present utility model is as follows:
The conducting strip 11 of caloric stimulation head 1 is placed stimulation point on the nuclear-magnetism environment environment subjects skin, and fix caloric stimulation head 1 with binder 17, the marking circuit places the subjects on hand.Opening power, water cycle is started working, and guarantees the stable of in when work caloric stimulation head water-cooling head 14 of 1 water temperature.
Setting in host computer 7 stimulates temperature, the stimulation temperature that the embedded Control circuit is set according to host computer, control D the A change-over circuit digital signal of temperature voltage is converted to analogue signal, be input in the electric current go to circuit through power amplification circuit, be input in the cooling piece 13 through behind the current-limiting protection circuit again, intensification or the cooling of control cooling piece 13, and then the temperature of control conducting strip 11; The resistance value that bridge circuit will be pasted thin film platinum resistance thermometer sensor, 12 between conducting strip 11 and cooling piece 13 converts magnitude of voltage to, be transferred in the A D change-over circuit and convert digital signal to, be transferred to again in the embedded processing circuit, the current temperature value that records is compared with set temperature value in the host computer, the embedded processing circuit judges increases or reduces temperature voltage, simultaneously the current temperature value that records is transferred to that storage shows not in the host computer 7.
The subjects moves the slide block marking of marking on the circuit according to current pain, and slide block links to each other with slide rheostat, the marking circuit with the resistance that changes by A the D change-over circuit connect the embedded Control circuit, the marking value is transferred to storage demonstration in the host computer.
When the cold stimulation that arranges in the host computer and thermostimulation change, embedded Control circuit control electric current go to circuit, make the on off state upset of relay, change sense of current in the current-limiting protection circuit, and then the current direction in the change cooling piece 13, make heating and the refrigerating function upset of cooling piece 13;
The actual score value that records temperature value and pain perception that storage shows in the host computer, for the experimenter to the pain perception research of human body and the analgesic effect evaluation of medicine.

Claims (10)

1. a skin temperature sensory stimuli system is characterized in that, comprises caloric stimulation head (1), catch net (2), cooling water tank (3), water pump (4), water-storing tank (5), embedded type control module (6) and host computer (7); Caloric stimulation head (1), cooling water tank (3), water pump (4) and water-storing tank (5) link to each other successively by water pipe, form water circulation system; Caloric stimulation head (1) is connected with host computer (7) by embedded type control module (6);
Described caloric stimulation head (1) comprises conducting strip (11), cooling piece (13), water-cooling head (14), shell (15), binder (17), button (18) and heat insulating mattress (19); The one side of cooling piece (13) is pasted conducting strip (11), and another side is pasted water-cooling head (14); Cooling piece (13) and water-cooling head (14) place in the cavity of conducting strip (11) and shell (15) composition; Heat insulating mattress (19) is pasted the front in shell (15); Binder (17) is fixed on the back side of shell (15) by button (18); Conducting strip (11) places the stimulation point on the human body skin;
Described embedded type control module (6), comprise embedded processing circuit, D A change-over circuit, power amplification circuit, electric current go to circuit, current-limiting protection circuit, bridge circuit, differential amplifier circuit, A D change-over circuit and marking circuit; This embedded processing circuit is according to the stimulation temperature that arranges in the host computer (7), produce the relevant voltage digital signal, input in the D A change-over circuit and convert analogue signal to, after being input to the electric current go to circuit after amplifying through power amplification circuit again, behind current-limiting protection circuit, be input to again in the cooling piece (13), intensification or the cooling of control cooling piece (13), and then control conducting strip (11) variations in temperature; The resistance value that this bridge circuit will be pasted thin film platinum resistance thermometer sensor, (12) between conducting strip (11) and cooling piece (13) converts magnitude of voltage to, be transferred in the A D change-over circuit and convert digital signal to, be transferred to again in the embedded processing circuit, current temperature value is compared with the set temperature value, judging increases or reduces voltage, and while embedded processing circuit is transferred to the middle storage of host computer (7) to current temperature value and shows; The subjects gives a mark according to the slide block that current pain moves on the slide rheostat, this marking circuit changes into magnitude of voltage with the resistance of slide rheostat, through A the D change-over circuit be connected to the embedded processing circuit, the embedded processing circuit is transferred to the marking value by serial ports that storage shows in the host computer (7).
2. skin temperature sensory stimuli as claimed in claim 1 system is characterized in that water-cooling head (14) comprises water inlet, outlet and internal channel (16); Internal channel (16) is the M shape, and is linked to be path with water inlet and the outlet of water-cooling head (14) the same side.
3. skin temperature sensory stimuli as claimed in claim 1 system is characterized in that conducting strip (11) is that the thickness that adopts the red copper material to make is the convex shape thin slice of 8mm, is divided into two-layerly up and down, and the area on upper strata is 1/2nd of lower floor's area; Cover has three-back-shaped heat insulating mattress (19) around the upper strata.
4. skin temperature sensory stimuli as claimed in claim 1 system it is characterized in that shell (15) is processed by 3mm fine copper thin plate, and the center at the back side is welded with fine copper matter button (18).
5. skin temperature sensory stimuli as claimed in claim 1 system is characterized in that bridge circuit is connected to form by thin film platinum resistance thermometer sensor, (12) and three substitutional resistances.
6. skin temperature sensory stimuli as claimed in claim 1 system is characterized in that connecting the water pipe of caloric stimulation head (1), the lead-in wire of thin film platinum resistance thermometer sensor, (12) and the lead-in wire of cooling piece (13) and all is placed in the catch net (12).
7. skin temperature sensory stimuli as claimed in claim 1 system, the circuit that it is characterized in that giving a mark comprises slide rheostat, divider resistance and the screening can of being made by pure copper material; Slide block is housed on the screening can and indicates the slider track scale, slide block connects slide rheostat.
8. skin temperature sensory stimuli as claimed in claim 1 system is characterized in that the embedded processing circuit, comprises STM32 processor, jtag interface circuit, real time clock circuit and serial communication circuit; Jtag interface circuit, real time clock circuit are connected with the STM32 processor respectively, and the STM32 processor links to each other with host computer (7) by serial communication circuit.
9. skin temperature sensory stimuli as claimed in claim 1 system is characterized in that the electric current go to circuit, comprises common collector amplifying circuit and relay; The input of common collector amplifying circuit connects the STM32 processor, and output connects relay.
10. skin temperature sensory stimuli as claimed in claim 1 system is characterized in that current-limiting protection circuit is made of automatic recovery fuse and resistance series connection.
CN201220143245.6U 2012-04-07 2012-04-07 Sensing and stimulating system of skin temperature Expired - Lifetime CN202699376U (en)

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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102579014A (en) * 2012-04-07 2012-07-18 西安电子科技大学 Cold/hot pain stimulation system
CN105640692A (en) * 2015-12-30 2016-06-08 东南大学 Intelligent temperature-control semiconductor cold-compress instrument
CN112933369A (en) * 2021-01-27 2021-06-11 东南大学 Cerebral apoplexy patient movement and sensory nerve combined rehabilitation device and control method

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102579014A (en) * 2012-04-07 2012-07-18 西安电子科技大学 Cold/hot pain stimulation system
CN102579014B (en) * 2012-04-07 2014-03-12 西安电子科技大学 Cold/hot pain stimulation system
CN105640692A (en) * 2015-12-30 2016-06-08 东南大学 Intelligent temperature-control semiconductor cold-compress instrument
CN112933369A (en) * 2021-01-27 2021-06-11 东南大学 Cerebral apoplexy patient movement and sensory nerve combined rehabilitation device and control method
CN112933369B (en) * 2021-01-27 2023-01-31 东南大学 Cerebral apoplexy patient movement and sensory nerve combined rehabilitation device and control method

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