CN202372577U - Pure steam conductivity online monitoring device for sodium hyaluronate production - Google Patents

Pure steam conductivity online monitoring device for sodium hyaluronate production Download PDF

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Publication number
CN202372577U
CN202372577U CN2011204882332U CN201120488233U CN202372577U CN 202372577 U CN202372577 U CN 202372577U CN 2011204882332 U CN2011204882332 U CN 2011204882332U CN 201120488233 U CN201120488233 U CN 201120488233U CN 202372577 U CN202372577 U CN 202372577U
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China
Prior art keywords
pure steam
purified water
heat exchanger
conductivity
tubular heat
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Expired - Lifetime
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CN2011204882332U
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Chinese (zh)
Inventor
刘万勇
余渊
钱正祥
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SHANGHAI JINGFENG PHARMACEUTICAL CO Ltd
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Priority to CN2011204882332U priority Critical patent/CN202372577U/en
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Abstract

The utility model discloses a pure steam conductivity online monitoring device for sodium hyaluronate production, which comprises a pure steam generator, a tubular heat exchanger and a conductivity monitoring device. A pure steam inlet and a pure steam condensed water outlet are arranged on a casing of the tubular heat exchanger, one end of a pipe pass is provided with a purified water inlet, and the other end of the pipe pass is provided with a heated purified water outlet. The purified water inlet is connected with a purified water source through a purified water inlet pipe, the heated purified water outlet is connected with a purified water inlet of the pure steam generator through a purified water conveying pipe and a purified water pump, a pure steam outlet of the pure steam generator is connected with a pure steam conveying header pipe, and the pure steam inlet on the casing of the tubular heat exchanger is connected with a branch of the pure steam conveying header pipe through a pure steam conveying branch pipe and a steam valve. The conductivity monitoring device is arranged on the pure steam condensed water outlet. The pure steam conductivity online monitoring device for the sodium hyaluronate production achieves pure steam conductivity online monitoring while the purified water is heated by the pure steam to achieve the effect of reducing consumption and saving energy.

Description

A kind of sodium hyaluronate production is with the conductivity on-Line Monitor Device of pure steam
Technical field:
The utility model relates to a kind of pure steam conductivity on-Line Monitor Device, and particularly a kind of sodium hyaluronate production is with the conductivity on-Line Monitor Device of pure steam.
Background technology:
Electrical conductivity of water is meant: at a certain temperature, and 1cm 2At a distance of the electrode of 1cm, the inverse of the resistivity that charged ion is moved in water is represented with μ s/cm usually.
For drug quality is provided, present national new edition GMP has proposed to monitor the requirement of its conductivity about pure steam, to improve the purity of pure steam, reduces the ion concentration in the pure steam.But in the sodium hyaluronate production run, pure steam can't be realized on-line monitoring at present.
The utility model content:
The utility model technical matters to be solved is in the existing sodium hyaluronate production run; Pure steam can't be realized online problems of monitoring and the conductivity on-Line Monitor Device of a kind of sodium hyaluronate production with pure steam is provided; This device is when realizing pure steam on-line monitoring conductivity; Can realize the pure steam of purified water condensation, and, reach the effect of energy-conservation of consumption reduction with pure Steam Heating purified water water inlet.
The utility model technical matters to be solved can realize through following technical scheme:
A kind of sodium hyaluronate production comprises pure steam generator with the conductivity on-Line Monitor Device of pure steam, it is characterized in that, also comprises a tubular heat exchanger and a monitored conductivity device, and the tube side of said tubular heat exchanger is walked purified water, and shell side is walked pure steam; Housing at said tubular heat exchanger is provided with pure steam inlet and the outlet of pure steam condensate (SC); Tube side one end of this tubular heat exchanger is the purified water import; The other end is the purified water outlet of heating back; Said purified water import connects the purified water water source through the purified water induction pipe; The purified water outlet of said heating back is connected with the purified water inlet of said pure steam generator with the purifying water pump through the purified water delivery pipe, and the pure steam (vapor) outlet of pure steam generator connects a pure steam delivery main, and the pure steam inlet on the said tubular heat exchanger housing carries arm to be connected with the branch of steam valve with said pure steam delivery main through pure steam; Said monitored conductivity device is arranged in the pure steam condensate (SC) outlet.
As the further improvement of the utility model, electropolishing is all carried out in the tubulation of said tubular heat exchanger outside and inside, in order to avoid polluted product.
As the improvement further of the utility model, the tubulation of said tubular heat exchanger is that the expanded joint formula connects.Compare with the welded type connected mode, reduced pad, and that solder joint is a stainless steel is the weakest, the place of corrosion at first, and expanded joint formula heat interchanger is in case take place to leak and can directly see, so that in time maintenance is changed.
The sodium hyaluronate production of the utility model is with the conductivity on-Line Monitor Device of pure steam; Drawing pure steam through the pure steam delivery main on the pure steam generator carries arm that pure steam is steamed to tell one the tunnel; Get into the shell side of tubular heat exchanger, be used to heat the purified water in the tube side, heated purified water gets into pure steam generator and produces pure steam; And the monitored conductivity device carries out the on-line monitoring conductivity to the condensed condensate water of pure steam, thereby has realized the on-line monitoring of pure steam.The utility model and with pure Steam Heating purified water, reaches the effect of energy-conservation of consumption reduction when realizing pure steam on-line monitoring conductivity.
Description of drawings
Fig. 1 is the synoptic diagram of the utility model sodium hyaluronate production with the conductivity on-Line Monitor Device of pure steam.
Embodiment:
For technological means, creation characteristic that the utility model is realized, reach purpose and be easy to understand understanding with effect, below in conjunction with accompanying drawing, further set forth the utility model.
Referring to Fig. 1, the sodium hyaluronate production shown in the figure comprises pure steam generator 1, tubular heat exchanger 3 and a monitored conductivity device 4 with the conductivity on-Line Monitor Device of pure steam, and the tube side of tubular heat exchanger 3 is walked purified water, and shell side is walked pure steam; Housing at tubular heat exchanger 3 is provided with pure steam inlet 10 and pure steam condensate (SC) outlet 8; Tube side one end of this tubular heat exchanger 3 is purified water import 11; The other end is heating back purified water outlet 12; Purified water import 12 connects the purified water water source through purified water induction pipe 6; The purified water outlet 12 of heating back is connected with the purified water inlet 13 of pure steam generator 1 with purifying water pump 2 through purified water delivery pipe 7, and the pure steam (vapor) outlet 14 of pure steam generator 1 connects a pure steam delivery main 5, and the pure steam inlet 10 on tubular heat exchanger 3 housings carries arm 9 to be connected with the branch of steam valve 15 with pure steam delivery main 5 through pure steam; Monitored conductivity device 4 is arranged in the pure steam condensate (SC) outlet 8.Electropolishing is all carried out in the tubulation outside and the inside of tubular heat exchanger 3, in order to avoid polluted product.The tubulation of tubular heat exchanger 3 is that the expanded joint formula connects.Compare with the welded type connected mode, reduced pad, and that solder joint is a stainless steel is the weakest, the place of corrosion at first, and tubular heat exchanger 3 is in case take place to leak and can directly see, so that in time maintenance is changed.
The pure steam that pure steam generator 1 produces is through 5 outputs of pure main steam header road; The pure steam of part wherein gets into heat exchanger 3 through the pure steam branch pipe road 9 of on pure main steam header road 5, drawing; In heat exchanger 3, be delivered to the cold purified water cooling in the tube side by purified water induction pipe 6; When cooled pure steam condensate (SC) discharges in pure steam condensate (SC) outlet 8; Can be installed in its conductivity of monitored conductivity table 4 on-line monitoring of pure steam condensate (SC) outlet 8; Simultaneously, become hot purified water after by pure Steam Heating, get into through purified water delivery pipe 7 and purifying water pump 2 and produce pure steam in the pure steam generators 1 through the cold purified water in the tube side of tubular heat exchanger 3.
The sodium hyaluronate production of the utility model tells one the tunnel with the conductivity on-Line Monitor Device of pure steam with the pure steam of output, is used to heat the purified water water inlet, simultaneously the condensate water of pure steam is carried out its conductivity of monitoring, and then the conductivity of the pure steam of on-line monitoring.Purified water has obtained preheating like this, and pure steam has been realized the on-line monitoring of conductivity, has satisfied the requirement of GMP about pure steam on-line monitoring conductivity, has obtained the effect of energy-conservation of consumption reduction simultaneously.
More than show and described the advantage of ultimate principle, principal character and the utility model of the utility model.The technician of the industry should understand; The utility model is not restricted to the described embodiments; The principle of describing in the foregoing description and the instructions that the utility model just is described; The utility model also has various changes and modifications under the prerequisite that does not break away from the utility model spirit and scope, and these variations and improvement all fall in the utility model scope that requires protection.The utility model requires protection domain to be defined by appending claims and equivalent thereof.

Claims (3)

1. a sodium hyaluronate production comprises pure steam generator with the conductivity on-Line Monitor Device of pure steam, it is characterized in that also comprise a tubular heat exchanger and a monitored conductivity device, the tube side of said tubular heat exchanger is walked purified water, and shell side is walked pure steam; Housing at said tubular heat exchanger is provided with pure steam inlet and the outlet of pure steam condensate (SC); Tube side one end of this tubular heat exchanger is the purified water import; The other end is the purified water outlet of heating back; Said purified water import connects the purified water water source through the purified water induction pipe; The purified water outlet of said heating back is connected with the purified water inlet of said pure steam generator with the purifying water pump through the purified water delivery pipe, and the pure steam (vapor) outlet of pure steam generator connects a pure steam delivery main, and the pure steam inlet on the said tubular heat exchanger housing carries arm to be connected with the branch of steam valve with said pure steam delivery main through pure steam; Said monitored conductivity device is arranged in the pure steam condensate (SC) outlet.
2. sodium hyaluronate production as claimed in claim 1 is characterized in that with the conductivity on-Line Monitor Device of pure steam electropolishing is all carried out in the tubulation outside and the inside of said tubular heat exchanger.
3. sodium hyaluronate production as claimed in claim 1 is characterized in that with the conductivity on-Line Monitor Device of pure steam the tubulation of said tubular heat exchanger is that the expanded joint formula connects.
CN2011204882332U 2011-11-30 2011-11-30 Pure steam conductivity online monitoring device for sodium hyaluronate production Expired - Lifetime CN202372577U (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN2011204882332U CN202372577U (en) 2011-11-30 2011-11-30 Pure steam conductivity online monitoring device for sodium hyaluronate production

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN2011204882332U CN202372577U (en) 2011-11-30 2011-11-30 Pure steam conductivity online monitoring device for sodium hyaluronate production

Publications (1)

Publication Number Publication Date
CN202372577U true CN202372577U (en) 2012-08-08

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Family Applications (1)

Application Number Title Priority Date Filing Date
CN2011204882332U Expired - Lifetime CN202372577U (en) 2011-11-30 2011-11-30 Pure steam conductivity online monitoring device for sodium hyaluronate production

Country Status (1)

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CN (1) CN202372577U (en)

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C14 Grant of patent or utility model
GR01 Patent grant
C56 Change in the name or address of the patentee
CP01 Change in the name or title of a patent holder

Address after: 200120 Shanghai city Baoshan District Luo Road No. 50

Patentee after: Shanghai Jingfeng Pharmaceutical Co., Ltd.

Address before: 200120 Shanghai city Baoshan District Luo Road No. 50

Patentee before: Shanghai Jingfeng Pharmaceutical Co., Ltd.

C56 Change in the name or address of the patentee
CP01 Change in the name or title of a patent holder

Address after: 200120 Shanghai city Baoshan District Luo Road No. 50

Patentee after: Shanghai Jingfeng Pharmaceutical Co., Ltd.

Address before: 200120 Shanghai city Baoshan District Luo Road No. 50

Patentee before: Shanghai Jingfeng Pharmaceutical Co., Ltd.

CX01 Expiry of patent term
CX01 Expiry of patent term

Granted publication date: 20120808