CN202366623U - Nuclear track membrane filtering device for liquid medicine production - Google Patents
Nuclear track membrane filtering device for liquid medicine production Download PDFInfo
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- CN202366623U CN202366623U CN2011205331905U CN201120533190U CN202366623U CN 202366623 U CN202366623 U CN 202366623U CN 2011205331905 U CN2011205331905 U CN 2011205331905U CN 201120533190 U CN201120533190 U CN 201120533190U CN 202366623 U CN202366623 U CN 202366623U
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Abstract
The utility model belongs to the technical field of pharmacy, and particularly relates to a nuclear track membrane filtering device for liquid medicine production. The nuclear track membrane filtering device comprises a liquid medicine pump, a stainless steel filter screen component and a filter component; an inlet of the liquid medicine pump is connected with a liquid medicine inlet pipe; the filter component is connected with a liquid medicine outlet pipe; and the filter component is a nuclear track membrane filter adopting a nuclear track membrane as a filtering layer. The liquid medicine separation efficiency of the nuclear track membrane filtering device for liquid medicine production is better than that of the prior art, and the problem that liquid medicine absorption and pollution caused by fiber filter paper in the prior art can be avoided.
Description
Technical field
The utility model belongs to the pharmaceutical technology field, is specifically related to a kind of nucleopore membranes filter that soup is produced that is used for.
Background technology
Have sediment and precipitate in the oral liquid of China's liquid preparation of Chinese medicine and the parenteral solution, the deposited phenomenon of some traditional Chinese medicine oral liquid and parenteral solution is more serious; (contain Western medicine) in the traditional Chinese medicine and have sediment and floccule, be not useable for hypodermic injection and intravenously administrable, otherwise very easily patient's health and lives is worked the mischief, sediment in the traditional Chinese medicine and floccule have been classified as harmful material.
Pharmaceutical industry is sought the otherwise effective technique solution for the sediment and the floccule that reduce, eliminate in the soup, transform traditional production process, and the membrane separation technique of pure physical property is its preferred option.
Membrane separation technique is widely applied to medicine, food, and chemical industry, electronics, fields such as environmental protection, the internal membrane isolation technics has formed an industry and has been the annual development trend that rises during the last ten years.The filter membrane material form that the film separation industries is adopted is varied, but its filter opening all is the filter membrane material that adopts web-like or sponge formula labyrinth-like mostly, resembles being had absorption to receive to deposit cash by the filter material; And ubiquity film contamination phenomenon, because its filter opening aperture disunity, the film material self has material such as fiber to come off; Particularly in the pressure filtration course of work; Its filter opening aperture changes, and causes the isolated by filtration quality to descend, and directly has influence on product quality.Nucleopore membranes, the ion miillpore filter or be called for short ionic membrane of weighing again is that my institute takes the lead in developing and the same with the nucleopore membranes quality of states' developments such as the U.S., Russia at home; It is cylindric that filter opening is; The accurate uniformity in aperture has good each item performance, and biochemical property is extremely stable; Biochemical reaction does not take place with quilt filter material in the level and smooth clean material that comes off that do not have of filter membrane itself.In the world nucleopore membranes to be that filter opening unique in the high molecular polymer diffusion barrier is cylindric, pore-size distribution very uniformly filter membrane be well-known; In the micro-filtration scope, also there is not the filter membrane of a kind of high molecular polymer filter membrane and other materials can reach the precision and the performance of nucleopore membranes, so nucleopore membranes is best first-selected filter membrane in the micro-filtration scope.
In film separating experiment and research, find that the large-scale grain diameter in " ANSHEN JIANNAO YE " oral liquid soup mainly concentrates on Φ 1-7 mu m range, belongs to the micron order scope.Find in the soup except that containing particle, to also have floccule in the experiment, the floccule content in each soup is different, and the existence of floccule and soup date of manufacture do not have direct relation.Also find to contain floccule in the part soup after investigating oral liquid and the traditional Chinese medicine injection of other kinds.Formed cream appearance gelatinous precipitate after particle in the soup and the floccule sedimentation, extracted the back floccule to the particulate separation in the deposition and be gluey.The experiment confirm floccule is that the soup deposition is the gluey main cause of cream appearance.Colloidal solid in the medicine is separated out back absorption each other in soup, produce the flocculation phenomenon, forms floccule gradually; In flocculation process and infall process; Particle in the soup swathes with floccule is in the same place, and makes that effective ingredient is adsorbed, embedding, causes a large amount of losses of active ingredient; Low drug effect particles such as starch, protein, cellulose, tannin again can accelerated reaction in sedimentary deposit, thereby the quality of soup is changed.Colloid in the medicine is particle form and is present in the soup, and its grain diameter is at micron order.Learn after the investigation in the traditional Chinese medicine floccule by national departments concerned qualitative be harmful substance, the traditional Chinese medicine injection that a lot of pharmaceutical factories produce on the market is stopped use, one of them reason is to contain floccule in the soup.
At the field of Chinese medicines, adopt the film pollution mechanism of other membrane filtration not clear so far, mostly contain protein in the liquid preparation of Chinese medicine; Fat, cellulose, tannin and colloidal substance thereof; Other filter membrane is prone to contaminated when filtering and stops up; Cause membrane flux to fall sharply, because the filter opening of film itself is netted or sponge formula labyrinth-like, its existing cleaning method is difficult to reach the purpose of eliminating obstruction recovery flux.
In a word, big medicine amount liquid causes cost significantly to raise thereby Chinese medicine filtering technique of the prior art not only exists absorption, the more important thing is the contaminated easily and obstruction in filter process of existing filter membrane, remains further to be improved.
Summary of the invention
(1) utility model purpose
For solving the problem that exists in the above-mentioned prior art, the purpose of the utility model provides a kind of nucleopore membranes filter that soup is produced that is used for.
(2) technical scheme
For achieving the above object, the technical scheme of the utility model realizes as follows:
A kind of nucleopore membranes filter that is used for soup production; Comprise the spray pump, stainless steel screen modules, the filter assemblies that connect successively through pipeline; The inlet of said spray pump links to each other with the soup inlet tube; Said filter links to each other with the medicine liquid outlet pipe, and wherein, said filter assemblies is to adopt the nuclepore filter assembly of nucleopore membranes as filter course.
The described nucleopore membranes filter that is used for soup production, wherein, said stainless steel screen modules comprises the first stainless steel screen pack, the second stainless steel screen pack and the 3rd stainless steel screen pack of series connection successively.
The described nucleopore membranes filter that is used for soup production; Wherein, Said stainless steel screen pack comprises the stainless steel casing of sealing, and by two that are provided with in the shell stainless steel filtering net support plates that have square hole stainless steel filtering net is solidificated in the centre, and the square hole on the said filter screen support plate becomes misconstruction.
The described nucleopore membranes filter that is used for soup production, wherein, said nuclepore filter assembly comprises first nuclepore filter and second nuclepore filter of series connection successively.
The described nucleopore membranes filter that is used for soup production, wherein, said nuclepore filter comprises envelope sealed, and supports the nucleopore membranes filter course that is placed in one by a net that is provided with in the shell.
The described nucleopore membranes filter that is used for soup production; Wherein, First valve and the 3rd valve are set respectively on the pipeline at said spray pump two ends; Wherein the other end of the 3rd valve connects the stainless steel screen modules, and the other end of first valve links to each other with the stainless steel filter assemblies through second valve.
The described nucleopore membranes filter that is used for soup production; Wherein, Set gradually first observation window and the 4th valve along the soup flow direction between said stainless steel screen modules and the nuclepore filter assembly; Between first nuclepore filter and second nuclepore filter, the 6th valve is set, between said second nuclepore filter and medicine liquid outlet pipe, sets gradually second observation window and the 8th valve along the soup flow direction.
The described nucleopore membranes filter that is used for soup production; Wherein, Also be parallel with spare core pore membrane filter assemblies circuit between said first observation window and the medicine liquid outlet pipe, said spare core pore membrane filter assemblies circuit upper edge soup flows to and sets gradually the 5th valve, the 3rd nuclepore filter, the 7th valve, the 4th nuclepore filter, the 3rd observation window and the 9th valve.
(3) beneficial effect
Adopt the described nucleopore membranes filter that is used for soup production of the utility model to carry out the experiment of separating liquid medicine, the ANSHEN JIANNAO YE oral liquid through nucleopore membranes film separating experiment after, relevant department of Tongrentang uses professional instrument such as high performance liquid chromatograph and method is tested to its sample through Beijing; Report data shows; The oral liquid soup of four lot numbers pH value before and after filtering does not change, the highest decline 3.47% of relative density, minimum decline 0.97%; Average decline 2.0275%; The cream appearance gelatinous precipitate of soup disappears, and soup inspection bottom after static state is placed a year has only denier to be the particles settling of thin loose sand shape, and particle diameter is below Ф 0.6 μ m; Medicinal liquid clarity improves a lot, and viscosity descends.Crucial effective component schizandrin content slightly descends but still is higher than acceptable quality level in the soup.After the nucleopore membranes separation, obviously improve the clarity and stability of ANSHEN JIANNAO YE oral liquid, through analysis of experimental data, Pharmaceutical Factory of Beijing University of Chinese Medicine experimentizes to detect to the nucleopore membranes filter effect proves that application prospect is arranged.
Description of drawings
Fig. 1 is the structural representation that the utility model is used for the nucleopore membranes filter that soup produces, and wherein 1 is respectively first to the 3rd observation window, 61～64 and is respectively first to fourth nuclepore filter, 7 and is the medicine liquid outlet pipe for spray pump, 41～43 is respectively first to the 3rd stainless steel screen pack, 51～53 for soup inlet tube, 21～29 is respectively first to the 9th valve, 3.
The specific embodiment
Further specify below in conjunction with the preferred embodiment of accompanying drawing the utility model.
This device is directed against common defects and the deficiency that filtering accuracy is inaccurate, rejection rate is low in pharmaceutical industry, food service industry, the chemical industry; And, be performance nucleopore membranes technical advantage, on the former scientific research project basis to not having the present situation of producing in the nucleopore membranes application with filter; Through the market surveys in 15 years, visit user, production scene on-the-spot investigation; On bases such as great amount of calculation, test, demonstration, revise design repeatedly, study intensively and produce this appliance arrangement.
A kind of nucleopore membranes filter that is used for soup production; Comprise the spray pump 3, stainless steel screen modules, the filter assemblies that connect successively through pipeline; The inlet of said spray pump 3 links to each other with soup inlet tube 1; Said filter links to each other with the medicine liquid outlet pipe, and wherein, said filter assemblies is to adopt the nuclepore filter assembly of nucleopore membranes as filter course.The direction that soup gets into filter is the place ahead.Said stainless steel filtering net assembly is used for the bigger impurity particle of filtering herb liquid, and said nucleopore membranes filter assemblies is used for the small impurity particle of filtering, can adopt different apertures nucleopore membranes according to the size of impurity particle in the required filtered medicine liquid.
Describedly be used for the nucleopore membranes filter that soup is produced, wherein, said stainless steel screen modules comprises the first stainless steel screen pack 41, the second stainless steel screen pack 42 and the 3rd stainless steel screen pack 43 of series connection successively.
The described nucleopore membranes filter that is used for soup production; Wherein, Said stainless steel screen pack comprises the stainless steel casing of sealing, and by two that are provided with in the shell stainless steel filtering net support plates that have square hole stainless steel filtering net is solidificated in the centre, and the square hole on the said filter screen support plate becomes misconstruction; Preventing that particle is detained in filtrating and the filtrating, and be the backwash condition that facilitates.
The described nucleopore membranes filter that is used for soup production, wherein, said nuclepore filter assembly comprises first nuclepore filter 61 and second nuclepore filter 62 of series connection successively.
The described nucleopore membranes filter that is used for soup production, wherein, said nuclepore filter comprises envelope sealed, and supports the nucleopore membranes filter course that is placed in one by a net that is provided with in the shell.
The described nucleopore membranes filter that is used for soup production; Wherein, First valve 21 and the 3rd valve 23 are set respectively on the pipeline at said spray pump 3 two ends; Wherein the other end of the 3rd valve 23 connects the stainless steel screen modules, and the other end of first valve 21 links to each other with the stainless steel filter assemblies through second valve 22.During filter work, second valve 22 is closed, and the 3rd valve 23 is opened, and soup is by filtering under spray pump 3 effects.
The described nucleopore membranes filter that is used for soup production; Wherein, Set gradually first observation window 51 and the 4th valve 24 along the soup flow direction between said stainless steel screen modules and the nuclepore filter assembly; Between first nuclepore filter 61 and second nuclepore filter 62, the 6th valve 26 is set, between said second nuclepore filter 62 and medicine liquid outlet pipe 7, sets gradually second observation window 52 and the 8th valve 28 along the soup flow direction.First observation window 51 is used to observe soup and flows to, and whether second observation window 52 is used to observe soup and clarifies.
The described nucleopore membranes filter that is used for soup production; Wherein, Also be parallel with spare core pore membrane filter assemblies circuit between said first observation window 51 and the medicine liquid outlet pipe 7, said spare core pore membrane filter assemblies circuit upper edge soup flows to and to set gradually the 5th valve 25, the 3rd nuclepore filter 63, the 7th valve 27, the 4th nuclepore filter 64, the 3rd observation window 53 and the 9th valve 29.After the some to be filtered, control valve, adopt spare core pore membrane filter assemblies circuit, under non-stop-machine situation, open the nuclepore filter loam cake manually, change nucleopore membranes, two-way nucleopore membranes filtering wheel swap-in is capable, with the continuity that guarantees to produce.
This device is taked the modularized design manufacturing, and complete equipment is divided into that filtrating is carried, three grades of series connection of stainless steel are filtered step by step, independent each two-stage of nucleopore membranes parallel connection is filtered step by step, observation window four part systems, can realize the backwash of package unit.The frequency conversion of filtrating delivery system pressures is adjustable; Three grades of series connection of stainless steel are filtered step by step; Be solidificated in stainless steel filtering net middle with two stainless steel filtering net support plates that have square hole; Two square hole stainless steel filtering net support plate square holes become misconstruction, preventing that particle is detained in filtrating and the filtrating, and are the backwash condition that facilitates; The nuclepore filter internal structure adopts double-deck net supporting structure through to collection of experiment data repeatedly, makes nucleopore membranes reduce to zero at the filter internal tension in order to strengthen the compressive resistance of nucleopore membranes, to adopt simultaneously, improves the mechanical strength of nucleopore membranes greatly.Independent each two-stage of nucleopore membranes parallel connection is filtered step by step, and filtrating is realized the terminal secondary filter here.This device all adopts the health grade stainless steel and meets the made that sanitary standard requires, and nontoxic, unharmful substance is separated out, and biochemical reaction is not taken place filtrating, and is high temperature resistant, not absorption filtrate.
The combination of knot that can be undone by a pull formula is adopted in connection between each level system; Pipeline, valve, observation window, spray pump, stainless steel screen pack, nuclepore filter etc. are interconnected; Both guaranteed that maintenance maintenance was convenient; Again can be according to soup output combining and configuring corresponding filter device, very convenient simultaneously sterilization, backwash to equipment are fit to the use of industries such as pharmacy, food, chemical industry, electronics.
The operation of this device is very convenient, as long as required filter liquide is gone into the inlet that soup is received device, starts spray pump, controls pressure, and liquid such as soup filter automatically, just can observe directly the filtration situation of liquid such as soup through observation window and flow pressure.
Above content is to combine preferred embodiment to specify what the utility model was done, can not assert that the specific embodiment of the utility model only limits to these explanations.Under the utility model, the those of ordinary skill of technical field, under the prerequisite that does not break away from the utility model design, can also make some simple deductions and conversion, all should be regarded as belonging to the protection domain of the utility model.
Claims (8)
1. one kind is used for the nucleopore membranes filter that soup is produced; Comprise the spray pump (3), stainless steel screen modules, the filter assemblies that connect successively through pipeline; The inlet of said spray pump (3) links to each other with soup inlet tube (1); Said filter links to each other with the medicine liquid outlet pipe, it is characterized in that: said filter assemblies is to adopt the nuclepore filter assembly of nucleopore membranes as filter course.
2. device according to claim 1 is characterized in that: said stainless steel screen modules comprises the first stainless steel screen pack (41), the second stainless steel screen pack (42) and the 3rd stainless steel screen pack (43) of series connection successively.
3. device according to claim 2; It is characterized in that: said stainless steel screen pack comprises the sealing stainless steel casing; And in the middle of by two that are provided with in the shell stainless steel filtering net support plates that have a square hole stainless steel filtering net being solidificated in, the square hole on the said filter screen support plate becomes misconstruction.
4. device according to claim 1 is characterized in that: said nuclepore filter assembly comprises first nuclepore filter (61) and second nuclepore filter (62) of series connection successively.
5. device according to claim 4 is characterized in that: said nuclepore filter comprises envelope sealed, and supports the nucleopore membranes filter course that is placed in one by a net that is provided with in the shell.
6. device according to claim 1; It is characterized in that: first valve (21) and the 3rd valve (23) are set respectively on the pipeline at said spray pump (3) two ends; Wherein the other end of the 3rd valve (23) connects the stainless steel screen modules, and the other end of first valve (21) links to each other with the stainless steel filter assemblies through second valve (22).
7. device according to claim 1; It is characterized in that: set gradually first observation window (51) and the 4th valve (24) along the soup flow direction between said stainless steel screen modules and the nuclepore filter assembly; Between first nuclepore filter (61) and second nuclepore filter (62), the 6th valve (26) is set, between said second nuclepore filter (62) and medicine liquid outlet pipe (7), sets gradually second observation window (52) and the 8th valve (28) along the soup flow direction.
8. device according to claim 7; It is characterized in that: also be parallel with spare core pore membrane filter assemblies circuit between said first observation window (51) and the medicine liquid outlet pipe (7), said spare core pore membrane filter assemblies circuit upper edge soup flows to and sets gradually the 5th valve (25), the 3rd nuclepore filter (63), the 7th valve (27), the 4th nuclepore filter (64), the 3rd observation window (53) and the 9th valve (29).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2011205331905U CN202366623U (en) | 2011-12-19 | 2011-12-19 | Nuclear track membrane filtering device for liquid medicine production |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2011205331905U CN202366623U (en) | 2011-12-19 | 2011-12-19 | Nuclear track membrane filtering device for liquid medicine production |
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| Publication Number | Publication Date |
|---|---|
| CN202366623U true CN202366623U (en) | 2012-08-08 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN2011205331905U Expired - Lifetime CN202366623U (en) | 2011-12-19 | 2011-12-19 | Nuclear track membrane filtering device for liquid medicine production |
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| Country | Link |
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| CN (1) | CN202366623U (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108744697A (en) * | 2018-07-28 | 2018-11-06 | 苏州汉德瑞生物工程有限公司 | A kind of food additives production filter device |
-
2011
- 2011-12-19 CN CN2011205331905U patent/CN202366623U/en not_active Expired - Lifetime
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108744697A (en) * | 2018-07-28 | 2018-11-06 | 苏州汉德瑞生物工程有限公司 | A kind of food additives production filter device |
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| Date | Code | Title | Description |
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| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| CX01 | Expiry of patent term | ||
| CX01 | Expiry of patent term |
Granted publication date: 20120808 |