CN202297580U - Device for increasing effectiveness of biochemical reagent and bio-enzyme - Google Patents
Device for increasing effectiveness of biochemical reagent and bio-enzyme Download PDFInfo
- Publication number
- CN202297580U CN202297580U CN 201120425030 CN201120425030U CN202297580U CN 202297580 U CN202297580 U CN 202297580U CN 201120425030 CN201120425030 CN 201120425030 CN 201120425030 U CN201120425030 U CN 201120425030U CN 202297580 U CN202297580 U CN 202297580U
- Authority
- CN
- China
- Prior art keywords
- reagent
- enzyme
- heat insulation
- bio
- insulation box
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 239000003153 chemical reaction reagent Substances 0.000 title claims abstract description 29
- 238000009413 insulation Methods 0.000 claims abstract description 17
- 102000004190 Enzymes Human genes 0.000 claims description 13
- 108090000790 Enzymes Proteins 0.000 claims description 13
- 238000005057 refrigeration Methods 0.000 claims description 4
- 238000004519 manufacturing process Methods 0.000 abstract description 9
- 239000002994 raw material Substances 0.000 abstract description 8
- 230000000694 effects Effects 0.000 abstract description 5
- 239000003960 organic solvent Substances 0.000 abstract description 3
- 230000035484 reaction time Effects 0.000 abstract description 2
- 150000002894 organic compounds Chemical class 0.000 abstract 1
- 230000002035 prolonged effect Effects 0.000 abstract 1
- 239000000463 material Substances 0.000 description 6
- 230000010355 oscillation Effects 0.000 description 4
- 230000010358 mechanical oscillation Effects 0.000 description 3
- 238000002203 pretreatment Methods 0.000 description 2
- 230000002950 deficient Effects 0.000 description 1
- 239000003085 diluting agent Substances 0.000 description 1
- 230000001105 regulatory effect Effects 0.000 description 1
- 238000004904 shortening Methods 0.000 description 1
- 230000006641 stabilisation Effects 0.000 description 1
- 238000011105 stabilization Methods 0.000 description 1
- 239000007858 starting material Substances 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
Images
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M21/00—Bioreactors or fermenters specially adapted for specific uses
- C12M21/18—Apparatus specially designed for the use of free, immobilized or carrier-bound enzymes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M23/00—Constructional details, e.g. recesses, hinges
- C12M23/34—Internal compartments or partitions
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M27/00—Means for mixing, agitating or circulating fluids in the vessel
- C12M27/10—Rotating vessel
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M35/00—Means for application of stress for stimulating the growth of microorganisms or the generation of fermentation or metabolic products; Means for electroporation or cell fusion
- C12M35/04—Mechanical means, e.g. sonic waves, stretching forces, pressure or shear stimuli
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
- C12M41/12—Means for regulation, monitoring, measurement or control, e.g. flow regulation of temperature
- C12M41/14—Incubators; Climatic chambers
Abstract
The utility model relates to a device for increasing the effectiveness of a biochemical reagent and a bio-enzyme. The prior art has many problems in producing the biochemical reagent. The device disclosed by the utility model comprises a heat insulation box, wherein a heat insulation cover plate is arranged on the heat insulation box; a treating chamber is arranged on the upper part in the heat insulation box, a refrigerating device and a control module are arranged at the lower part in the heat insulation box, a plurality of ultrasonic wave generators are arranged at the periphery and the bottom of the treating chamber, and the control module is in signal connection with the ultrasonic wave generator; and the treating chamber is internally provided with a rotary platform, a motor is connected with the rotary platform in a matching manner through a belt, and a treating container is arranged on the rotary platform. According to the utility model, organic compound and bio-enzyme raw materials can be pretreated before production, so that the influence of an organic solvent to a formula is eliminated during reagent production, the solubility is increased and the stability of the reagent is enhanced; and the activity of the treated bio-enzyme can be increased by 20-30%, and the reaction time of the reagent is shortened correspondingly; meanwhile, the quality guarantee period of the reagent is prolonged and the quality and the grade of the reagent are greatly increased.
Description
Technical field
The utility model belongs to the production unit technical field of chemical reagent biological products reaction; Being specifically related to a kind of raising biochemical reagents and enzyme usefulness device, is that a kind of biochemical reagents that are applied to are produced the central pre-treatment production equipment that improves biochemical reagents and enzyme raw material efficient.
Background technology
Raw material in the middle of the biochemical reagents production mainly cooperates with staples such as organic cpds, inorganics and enzymes and forms, and the biochemical reagents of domestic production make the reagent of producing exist following problem owing to receive the influence of factors such as the reagent raw material is impure, of low quality: 1. the error of between-lot is bigger in clinical labororatory's application; Result's stability, repeatability relatively poor; 3. experimental result is unstable; 4. the quality guaranteed period is short.Above problems have produced very big difficulty to the production and selling of biochemical reagents.
Summary of the invention
The purpose of the utility model is exactly the defective to existing production technology and raw material, and a kind of raising biochemical reagents and enzyme usefulness device are provided.
The utility model comprises insulation can, and insulation can is provided with the insulation cover plate; The insulation can internal upper part is provided with treatment chamber, the bottom is provided with refrigeration plant and control module, and around the treatment chamber and bottom is provided with a plurality of ultrasonic generators, and control module is connected with the ultrasonic generator signal; Be provided with rotation platform in the treatment chamber, motor is connected through belt and rotation platform, and processing vessel places on the rotation platform.
The utility model can carry out pre-treatment with organic cpds and enzyme raw material before production; Need not again of organic cpds gone dissolving with organic solvent; Eliminated reagent produce in the middle of organic solvent to the influence of prescription, improved the stability that solubleness has strengthened reagent; The activity of handling the artifact enzyme can improve 20～30%, the corresponding shortening of the reaction times of reagent; Increase the quality guaranteed period of reagent simultaneously, improved the quality and the quality of reagent greatly.
Description of drawings
Fig. 1 is the structural representation of the utility model.
Embodiment
As shown in Figure 1, a kind of raising biochemical reagents and enzyme usefulness device comprise insulation can 1, and insulation can 1 is provided with insulation cover plate 2; Insulation can 1 internal upper part is provided with treatment chamber 3, the bottom is provided with refrigeration plant 4 and control module 5, and around the treatment chamber 1 and bottom is provided with a plurality of ultrasonic generators 6, and control module 5 is connected with ultrasonic generator 6 signals; Be provided with rotation platform 7 in the treatment chamber 3, motor 8 is connected through belt and rotation platform 7, the rotation of controls revolution platform 7, and processing vessel 9 places on the rotation platform 7.
During use, at first open refrigeration plant 4, when the temperature of treatment chamber 3 is lower than below 0 ℃, will be incubated cover plate 2 and dig; Put into pending material the processing vessel 9 of treatment chamber 3; Starter motor 8, rotation platform 7 rotations make pending material reach even HF oscillation effect; Control module 5 is sent ultrasonic high-frequency sasser according to the different ultrasonic generators 6 of regulating automatically of the material of different treatment material; The material of pending material propagates into medium through the UW HF oscillation through the high frequency mechanical oscillation, handles to improve biochemical reagents physical and chemical performance and enzyme raw material efficient through 30～60 minutes.
Verify through actually operating: the low biochemical reagents raw material of some solubleness sends the frequency of ultrasonic scope via ultrasonic generator under the environment of low temperature (below 0 ℃) be the conspicuous high-frequency oscillation signal of 2 * 10E10～2 * 10E12; Convert the high frequency mechanical oscillation to through transverter and propagate into medium; Be used special-purpose diluent and impel molecule is become unbound state, on the basis that does not change the biochemical reagents feedstock property, reached stabilization on the contrary; Enzyme sends the frequency of ultrasonic scope via ultrasonic generator under the environment of low temperature (below 0 ℃) be the conspicuous high-frequency oscillation signal of 2 * 10E4～2 * 10E8; Convert the high frequency mechanical oscillation to through transverter and propagate into medium; Activate the activity of enzyme greatly, impelled biological enzyme activity to increase by 20～30%.
Claims (1)
1. one kind is improved biochemical reagents and enzyme usefulness device; Comprise insulation can; Insulation can is provided with the insulation cover plate, it is characterized in that: the insulation can internal upper part is provided with treatment chamber, and the bottom is provided with refrigeration plant and control module; Around the treatment chamber and bottom is provided with a plurality of ultrasonic generators, and control module is connected with the ultrasonic generator signal; Be provided with rotation platform in the treatment chamber, motor is connected through belt and rotation platform, and processing vessel places on the rotation platform.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 201120425030 CN202297580U (en) | 2011-11-01 | 2011-11-01 | Device for increasing effectiveness of biochemical reagent and bio-enzyme |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 201120425030 CN202297580U (en) | 2011-11-01 | 2011-11-01 | Device for increasing effectiveness of biochemical reagent and bio-enzyme |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN202297580U true CN202297580U (en) | 2012-07-04 |
Family
ID=46366516
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 201120425030 Expired - Lifetime CN202297580U (en) | 2011-11-01 | 2011-11-01 | Device for increasing effectiveness of biochemical reagent and bio-enzyme |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN202297580U (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2018077352A1 (en) * | 2016-10-28 | 2018-05-03 | Als Automated Lab Solutions Gmbh | Apparatus and method for handling samples containing biological cells |
| CN114588818A (en) * | 2021-12-27 | 2022-06-07 | 杭州康大晨星医学科技有限公司 | Homogenate device is used in reagent production |
-
2011
- 2011-11-01 CN CN 201120425030 patent/CN202297580U/en not_active Expired - Lifetime
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2018077352A1 (en) * | 2016-10-28 | 2018-05-03 | Als Automated Lab Solutions Gmbh | Apparatus and method for handling samples containing biological cells |
| US10907129B2 (en) | 2016-10-28 | 2021-02-02 | Als Automated Lab Solutions Gmbh | Apparatus for processing samples containing biological cells |
| CN114588818A (en) * | 2021-12-27 | 2022-06-07 | 杭州康大晨星医学科技有限公司 | Homogenate device is used in reagent production |
| CN114588818B (en) * | 2021-12-27 | 2023-10-13 | 杭州康大晨星医学科技有限公司 | Homogenizing device for reagent production |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| ASS | Succession or assignment of patent right |
Owner name: BEIJING CONDOR-TECO MEDICAL TECHNOLOGY CO., LTD. Effective date: 20130813 |
|
| C41 | Transfer of patent application or patent right or utility model | ||
| TR01 | Transfer of patent right |
Effective date of registration: 20130813 Address after: 311215 Construction No. four, No. 99, Xiaoshan District, Zhejiang, Hangzhou Patentee after: Hangzhou Shiji Kangda Medical Equipment Co.,Ltd. Patentee after: Beijing Condor-Teco Medical Technology Co.,Ltd. Address before: 311215 Construction No. four, No. 99, Xiaoshan District, Zhejiang, Hangzhou Patentee before: Hangzhou Shiji Kangda Medical Equipment Co.,Ltd. |
|
| ASS | Succession or assignment of patent right |
Free format text: FORMER OWNER: BEIJING CONDOR-TECO MEDICAL TECHNOLOGY CO., LTD. Effective date: 20150129 |
|
| C41 | Transfer of patent application or patent right or utility model | ||
| C56 | Change in the name or address of the patentee |
Owner name: ZHEJIANG CENTURY CONDOR MEDICAL SCIENCE + TECHNOLO Free format text: FORMER NAME: ZHEJIANG CENTURY CONDOR MEDICAL TECHNOLOGY CO., LTD. |
|
| CP01 | Change in the name or title of a patent holder |
Address after: 311215 Construction No. four, No. 99, Xiaoshan District, Zhejiang, Hangzhou Patentee after: ZHEJIANG CENTURY CONDOR MEDICAL SCIENCE & TECHNOLOGY Co.,Ltd. Patentee after: Beijing Condor-Teco Medical Technology Co.,Ltd. Address before: 311215 Construction No. four, No. 99, Xiaoshan District, Zhejiang, Hangzhou Patentee before: Hangzhou Shiji Kangda Medical Equipment Co.,Ltd. Patentee before: Beijing Condor-Teco Medical Technology Co.,Ltd. |
|
| TR01 | Transfer of patent right |
Effective date of registration: 20150129 Address after: 311215 Construction No. four, No. 99, Xiaoshan District, Zhejiang, Hangzhou Patentee after: ZHEJIANG CENTURY CONDOR MEDICAL SCIENCE & TECHNOLOGY Co.,Ltd. Address before: 311215 Construction No. four, No. 99, Xiaoshan District, Zhejiang, Hangzhou Patentee before: ZHEJIANG CENTURY CONDOR MEDICAL SCIENCE & TECHNOLOGY Co.,Ltd. Patentee before: Beijing Condor-Teco Medical Technology Co.,Ltd. |
|
| C56 | Change in the name or address of the patentee | ||
| CP02 | Change in the address of a patent holder |
Address after: 311215 Zhejiang economic and Technological Development Zone, Xiaoshan District, Xiaoshan, No. four, building No. 1368 Road, No. Patentee after: ZHEJIANG CENTURY CONDOR MEDICAL SCIENCE & TECHNOLOGY Co.,Ltd. Address before: 311215 Construction No. four, No. 99, Xiaoshan District, Zhejiang, Hangzhou Patentee before: ZHEJIANG CENTURY CONDOR MEDICAL SCIENCE & TECHNOLOGY Co.,Ltd. |
|
| CX01 | Expiry of patent term |
Granted publication date: 20120704 |
|
| CX01 | Expiry of patent term |