CN202211713U - Acoustoelectric conjoint analysis device for detecting tumors - Google Patents
Acoustoelectric conjoint analysis device for detecting tumors Download PDFInfo
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- CN202211713U CN202211713U CN2011203055830U CN201120305583U CN202211713U CN 202211713 U CN202211713 U CN 202211713U CN 2011203055830 U CN2011203055830 U CN 2011203055830U CN 201120305583 U CN201120305583 U CN 201120305583U CN 202211713 U CN202211713 U CN 202211713U
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Abstract
The utility model provides an acoustoelectric conjoint analysis device for detecting tumors, comprising a signal source stimulating module, a detecting signal transmitting and receiving module, a data acquisition module, an imaging processing module and an image conjoint analysis module which are successively connected. The analysis device can simultaneously transmit high-frequency ultrasonic signals and UWB (ultra wide bandwidth) electromagnetic wave signals to detect tissues of human bodies, backward waves are in signal processing and imaging algorithm processing after being received, so that gray scales relevant to the ultrasonic signals and the electromagnetic wave signals are respectively obtained, finally, the two gray scales are comprehensively processed and analyzed and are complemented by the aid of high specificity of ultrasonic imaging and high sensitivity of UWB electromagnetic wave imaging, and accordingly more detection details are obtained so as to carry out more accurate pathologic analysis.
Description
Technical field
This utility model belongs to the medical science technical field of detection, is specifically related to ultra sonic imaging, ultra broadband imaging, complementary series coded pulse detection and image association analytical equipment.
Background technology
Cancer is the frequently-occurring disease and the commonly encountered diseases of one type of serious threat human health.Over nearly 30 years, cancer morbidity and mortality rate are in rising trend always.Related data shows that tumor has become one of major causes of death of China resident, and the form of resisting cancer is quite severe.
Though the tumor Medical Technology of bringing in constant renewal in has been gathered various means such as operation, radiotherapy, chemotherapy, biological gene, be middle and advanced stage when finding cancer owing to the most tumors patient, good again Therapeutic Method also can only be felt frustrated.So, how correctly to diagnose out tumor in early days in cancer, for plenty of time is won in treatment, just become the key point that can cure tumor.
At present, medically had several different methods and tumor is detected and formed images, like X ray photography, computed tomography, NMR-imaging, ultrasound detection and ultra broadband near field imaging technique etc.X ray photography is lower for the sensitivity of the infantile tumour of no calcification, thereby faults rate and loss are all higher, and accepts the X-ray irradiation repeatedly and can cause ionizing radiation to gather in vivo, might cause the normal structure canceration.The photography of computed tomography and X ray exists same problem: the radiation of tomoscan can penetration cell, destroy DNA, even brings out some cancerous cell.Though nuclear magnetic resonance technique does not have harmful effect to human body, its spatial resolution is not as good as computed tomography, and equipment cost is expensive, is not suitable for large-scale mass survey.Yet the performance of two kinds of technology of ultra sonic imaging and ultra broadband (UWB) imaging is comparatively desirable.
Ultrasonic imaging technique is whether the decay according to ultrasonic echo detects and have abnormal structure to exist.Ultrasonic in medium with straightline propagation, good directivity is arranged, this is the basis of tissue or organ being detected with ultrasonic.When ultrasound wave arrives the interface of the different adjacent media of two kinds of acoustic impedances, will reflect, and acoustic impedance difference is big more, volume reflection is also big more.Acoustic impedance is defined as: Z=P*C, and P is a Media density in the formula, C is the velocity of sound in the tissue.Generally speaking, the spread speed of the velocity of sound in tissue changes little, about 1500m/s, changes.Research shows that the density of tumor tissues will be far longer than normal structure, so the two acoustic impedance exists than big-difference, and promptly tumor tissues has stronger acoustic reflection and scattering effect than near normal structure.The pick off at receiving transducer place is collected echo, and forms the image contrast scattergram of different material, tissue or organ by algorithm process.On ultrasonoscopy, strong echo is reflected as Bai Ying (clear zone), weak echo or do not have echo and be reflected as shadow (dark space).Ultrasonic detecting technology have high specific, non-invasive, equipment cost is low and resolution than advantages such as height, be applicable to that lump is less, the clinical focus that down is difficult for touching.
The UWB imaging technique is whether the decay according to signal echo detects and have abnormal structure to exist equally.UWB electromagnetic wave propagation characteristic is relevant with the dielectric property of tissue; The difference in dielectric constant of two media is big more, and its electromagnetic volume reflection in interface place is just big more, and dielectric property is with organizing liquid content that substantial connection is arranged; Research shows; The liquid content of general tumor tissues will far above around normal structure, so the dielectric property of tumor tissues and normal structure differs greatly, so electromagnetic wave signal is at bigger reflection and the scattered quantum of its interface place generation.Receptor is collected echo, and handles, forms images.The UWB detection signal is generally the burst pulse of ns level, and penetration power is strong, and positioning accuracy is high, in being detected as picture, has hypersensitivity, is easy to find infantile tumour; In addition, the UWB signal energy is little, and the X-ray imaging is much little to the harm of human body relatively.Therefore this technology has sizable clinical meaning.
The utility model content
Based on the important meaning of tumor Detection Techniques, to the know-why and the advantage of the not enough of prior art and combined echocardiography imaging and UWB imaging, this utility model proposes a kind of acoustoelectric combined analytical equipment that tumor is surveyed that is used for.Consider that acoustical signal detects acoustic characteristic and electrology characteristic that with electromagnetic wave signal detection has utilized material respectively, and these two kinds of signals can not interfere with each other, so their transmitting terminal can be integrated in the less module, and can detect target simultaneously.This utility model launches high-frequency ultrasonic signal simultaneously and the UWB electromagnetic wave signal detects tissue; Obtain gray-scale map respectively through signal processing and imaging algorithm processing after receiving echo about ultrasonic signal and electromagnetic wave signal; At last two width of cloth gray-scale maps are carried out integrated treatment and analysis; Utilize the high specific of ultra sonic imaging and the hypersensitivity of UWB electromagnetic wave imaging to carry out complementation, to obtain more detection details and to make pathological analysis more accurately.
For achieving the above object, this utility model adopts following technical scheme:
A kind of acoustoelectric combined analytical equipment that is used for the tumor detection; Comprise the signal source stimulating module that is used for producing simultaneously one road high frequency complementary series coded pulse excitation and one road UWB complementary series coded pulse excitation; Be used for launching high-frequency ultrasonic signal and UWB electromagnetic wave signal simultaneously and receive the detectable signal transceiver module that echo carries out sending to after complementary series is decoded data acquisition module; The data acquisition module that is used to gather the decoded echo-signal of two-way and produces imaging data; Be used to generate about the gray-scale map of ultrasonic signal and about the gray-scale map of electromagnetic wave signal and with two width of cloth gray-scale maps deliver to the imaging processing module of image association analysis module and be used for to two width of cloth figure carry out difference extract with feature extraction after formation characteristic pattern and make the image association analysis module of pathological analysis; Said signal source stimulating module, detectable signal transceiver module, data acquisition module, imaging processing module and image association analysis module are connected in order.
Said signal source stimulating module comprises the high-frequency impulse formation device and the first complementary series encoder that is used to produce high frequency complementary series coded pulse excitation, also comprises being used to produce UWB complementary series coded pulse excitation other the UWB pulse shaper and the second complementary series encoder.
Said detectable signal transceiver module comprises the ultrasonic probe that is used for after high frequency complementary series coded pulse excitation, launching the high frequency ultrasound detection signal and receives echo-signal; Be used for through UWB complementary series coded pulse excitation back emission UWB Electromagnetic Wave Detection signal and receive the electromagnetic antenna of echo-signal and be used for the two-way echo-signal is carried out being sent to after complementary series is decoded the decoder of data acquisition module.
In the above-mentioned analytical equipment; Said complementary series encoder adopts the complementary series sign indicating number as coded pulse sequence, and the activation sequence of said encoder output is made up of two 16 complementary series A, B, and activation sequence C is by A; The B composition that is connected, the complementary series sign indicating number has autocorrelation performance.
In the above-mentioned analytical equipment; Said detectable signal transceiver module comprises ultrasonic probe, electromagnetic antenna and the decoder of receiving and dispatching consubstantiality; Ultrasonic probe and electromagnetic antenna are respectively after coded pulse of high frequency complementary series and UWB complementary series coded pulse excitation; Scan to surveyed area simultaneously, launch high frequency ultrasound detection signal and UWB Electromagnetic Wave Detection signal respectively, and receive echo-signal separately; Decoder carries out being sent to data acquisition module after the complementary series decoding to the two-way echo-signal.
In the above-mentioned analytical equipment, said data acquisition equipment is handled respectively the decoded echo-signal of two-way: the detection of echoes signal intensity generates normalized intensity level s; Form then data format for ((x, y), two paths of data s), and deliver to the imaging processing module, wherein x and y are respectively the abscissa and the vertical coordinates of scan objects point.
In the above-mentioned analytical equipment; Said imaging processing module utilizes imaging algorithm that the two-way echo strength Value Data that receives is carried out imaging processing respectively; Generation is about the gray-scale map of ultrasonic signal with about the gray-scale map of electromagnetic wave signal, and two width of cloth gray-scale maps are delivered to the image association analysis module.
In the above-mentioned analytical equipment, said image association analysis module receives two width of cloth gray-scale maps that the imaging processing module transmits, and utilizes the high specific of ultra sonic imaging and the hypersensitivity of UWB electromagnetic wave imaging to carry out complementation, and makes pathological analysis.
In the above-mentioned analytical equipment, work below the completion of image association analysis module:
The first, in the UWB signal graph, extract the zone that is lower than preset gate limit value TH with ultrasonic signal figure dependency, form " acoustoelectric signal disparity map ", and be presented on the display separately;
The second, ultrasonic signal figure and UWB signal graph are transformed on " feature space " from " coordinate-gray value space ", the comparison through the characteristic pattern provides reference information Xiang the doctor; The image association analysis module at first extracts eigenvalue separately to two width of cloth gray-scale maps, in identical feature space, forms the characteristic pattern; Calculate the center of gravity O of two characteristic patterns then respectively
1And O
2, and calculate O
1And O
2Distance B in feature space=| O
1-O
2|; At last carry out following analysis according to the value of D:
(1) if satisfy D＞Th, then two characteristic pattern similarities are high, and the detection effect basically identical of two paths of signals is described;
(2) if satisfy Tl＜D＜Th, then two characteristic patterns are similar not high, and instruction book is analyzed from UWB electromagnetic wave image may cause erroneous judgement, and prompting must be analyzed just with reference to ultrasonic signal figure and can draw conclusion more accurately thus;
(3) if satisfy D＜Tl, then two characteristic pattern similarities are very low, explain wherein and one the tunnel detect and possibly make mistakes that the information that these two width of cloth gray-scale maps that draw are provided maybe be unreliable, need to consider to detect again, and wherein Tl and Th are the threshold values of presetting.
The analytical method of above-mentioned analytical equipment may further comprise the steps:
Step 1, in the signal source stimulating module, the output of high frequency pulse generator produces high-frequency coding pulse excitation sequence through the complementary series encoder; The output of UWB pulse shaper produces UWB coded pulse activation sequence through the complementary series encoder.Excitation signals is sent to the detectable signal transceiver module simultaneously.
After ultrasonic probe in step 2, the detectable signal transceiver module and electromagnetic antenna are encouraged, launch high frequency ultrasound pulse sequence signal and UWB electromagnetic impulse sequence signal respectively, simultaneously surveyed area is scanned.
Ultrasonic probe in step 3, the detectable signal transceiver module and electromagnetic antenna receive the echo of high-frequency ultrasonic signal and the echo of UWB electromagnetic wave signal respectively, and two-way echo-signal input decoder is decoded.
Step 4, decoded two paths of signals get into data acquisition module, and this module is handled decoded echo-signal, produce required " coordinate-intensity " data of imaging, and data are delivered to the imaging processing module through two-way.
Step 5, imaging processing module utilize imaging algorithm that the two paths of data that receives is carried out imaging processing respectively, generate about the gray-scale map of ultrasonic signal with about the gray-scale map of electromagnetic wave signal, and two width of cloth gray-scale maps are delivered to the image association analysis module.
Step 6, said image association analysis module carry out conjoint analysis to figure of high-frequency ultrasonic signal and the UWB electromagnetic wave signal figure that the imaging processing module transmits: at first in the UWB signal graph, extract the zone that is lower than preset gate limit value TH with ultrasonic signal figure dependency; Form " acoustoelectric signal disparity map ", let the doctor that the tumor character is made preliminary assurance intuitively, fast; Then ultrasonic signal figure and UWB signal graph are transformed on " feature space " from " coordinate-gray value space "; Form the characteristic pattern; And calculate the distance of geometric center of gravity in feature space of these two characteristic patterns, reliable with judging whether of this time making of this value checking.
The technical scheme of this utility model is integrated supersonic sounding and UWB electromagnetic wave detection has following advantage and technique effect:
1, utilize the acoustic characteristic of material and electrology characteristic to survey simultaneously, two kinds of different detectable signals of physical property are carried out integrated treatment and analysis, thereby obtain more target detail, making has more reference information when analyzing pathology character.
2, utilize the high specific of ultra sonic imaging to reduce the erroneous judgement situation that causes because of UWB imaging hypersensitivity, thereby improve the accuracy of pathological analysis; Utilize the hypersensitivity and the pinpoint accuracy of UWB imaging to obtain the edge details abundanter, thereby obtain more pathological informations as analyzing foundation than ultra sonic imaging.
3, ultrasonic signal and electromagnetic wave signal do not disturb mutually; Its transmitting terminal can be integrated in the less module; And can transmit and receive this two kinds of detection signals simultaneously, and therefore to compare with the single checkout gear of planting signal of emission, this utility model can't expend the more time cost.
4, adopt the complementary series coded pulse to survey, can obtain higher signal to noise ratio.
Description of drawings
Fig. 1 is the theory diagram of this utility model;
Fig. 2 a is the ultra sonic imaging sketch map of tumor;
Fig. 2 b is the UWB imaging sketch map of tumor;
Fig. 2 c is the acoustoelectric signal disparity map of tumor;
Fig. 3 is the workflow diagram of this utility model;
Fig. 4 is the workflow diagram of image association analysis module;
Fig. 5 a is the figure of a high-frequency ultrasonic signal characteristic pattern sketch map;
Fig. 5 b is a UWB electromagnetic wave signal figure characteristic pattern sketch map.
The specific embodiment
Below in conjunction with embodiment and accompanying drawing the present invention is described in further detail, but embodiment of the present invention is not limited thereto.
Embodiment
As shown in Figure 1, the present invention is made up of 5 modules: signal source stimulating module, detectable signal transceiver module, data acquisition module, imaging processing module and image association analysis module.Wherein, dotted arrow is represented detectable signal in the direction of propagation that produces, sends the stage, and solid arrow representes that echo-signal is in the direction of propagation that receives, handles, forms images the stage.The signal source stimulating module produces one road high frequency complementary series coded pulse excitation and one road UWB complementary series coded pulse excitation simultaneously, after the detectable signal transceiver module excited target, simultaneously to surveyed area emission high-frequency ultrasonic signal and UWB electromagnetic wave signal; The detectable signal transceiver module receives the echo of two kinds of signals, and the two-way echo-signal is decoded and delivered to data acquisition module; Data acquisition module, this module is handled respectively the decoded echo-signal of two-way, produces the required data of imaging, again two paths of data is delivered to the imaging processing module; The imaging processing module utilizes imaging algorithm that the two paths of data that receives is handled respectively, generates about the gray-scale map of ultrasonic signal with about the gray-scale map of electromagnetic wave signal, and two width of cloth gray-scale maps are delivered to the image association analysis module; The image association analysis module carries out difference to two width of cloth figure and extracts and feature extraction, forms the characteristic pattern, and makes analysis-by-synthesis.
Said signal source stimulating module comprises two-way excitation output.One route high-frequency impulse forms device and constitutes based on the first complementary series encoder of DSP TMS320C50, produces sequence of high frequency pulses, is used to encourage the ultrasonic probe of detectable signal transceiver module; Another route UWB pulse shaper and constitute based on the second complementary series encoder of DSPTMS320C50; The UWB pulse shaper produces Gauss's burst pulse; Through encoder production burst sequence, this UWB pulse train is used to encourage the electromagnetic antenna of detectable signal transceiver module.
Adopt the coded pulse energisation mode to survey here and can obtain higher signal to noise ratio, its principle is following:
Suppose that the quantity of information that gets into decoder is: C
i=B
iLog
2(1+S
i/ N
i), decoder is B with bandwidth
iInput signal to be demodulated into bandwidth be B
oThe output signal, its quantity of information is: C
o=B
oLog
2(1+S
o/ N
o).C is a quantity of information in the formula; B is a signal bandwidth; S is a signal power; The N noise power; Subscript i, o represent the decoder input and output respectively.Because the input signal of decoder must have equal quantity of information with the output signal, promptly have: B
iLog
2(1+S
i/ N
i)=B
oLog
2(1+S
o/ N
o).Generally speaking, S/N＞＞1, then (B
i/ B
o) log
2(S
i/ N
i) ≈ log
2(S
o/ N
o), and because chnnel coding has increased redundancy to information source, therefore the signal of signal behind ratio decoder in the unit interval before the decoding has bigger data volume, and B is promptly arranged
i＞B
oSo, S
o/ N
o＞S
i/ N
i, so coding system can be obtained higher signal to noise ratio.
The present invention adopts the complementary series sign indicating number as coded pulse sequence.The activation sequence of said encoder output is made up of two 16 complementary series A, B, and activation sequence C is by A, the B composition that is connected.The complementary series sign indicating number has ideal autocorrelation performance, and good autocorrelation performance can guarantee can be formed images clearly after echo-signal is through decoding.
Said detectable signal transceiver module is formed by the ultrasonic probe, electromagnetic antenna of transmitting-receiving consubstantiality with based on the decoder of DSPTMS320C50.Ultrasonic probe and electromagnetic antenna are respectively after coded pulse of high frequency complementary series and UWB complementary series coded pulse excitation; Scan to surveyed area simultaneously; Launch high frequency ultrasound detection signal and UWB Electromagnetic Wave Detection signal respectively, and receive echo-signal separately.Because acoustical signal is different with signal of telecommunication physical property, do not disturb mutually, therefore can in same module, transmit and receive simultaneously.Decoder carries out being sent to data acquisition module after the complementary series decoding to the two-way echo-signal.
Said data acquisition module adopts the EM200 module of Huawei Company, and the decoded echo-signal of two-way is handled respectively: the detection of echoes signal intensity generates normalized intensity level s; Form then data format for ((x, y), two paths of data s), and deliver to the imaging processing module, wherein x and y are respectively the abscissa and the vertical coordinates of scan objects point.
Said imaging processing module adopts the TMS34020 chip of TI company; Utilize imaging algorithm that the two-way echo strength Value Data that receives is carried out imaging processing respectively; Generation is about the gray-scale map of ultrasonic signal with about the gray-scale map of electromagnetic wave signal, and two width of cloth gray-scale maps are delivered to the image association analysis module.
Said image association analysis module is realized that by computer software two width of cloth gray-scale maps that the imaging processing module is transmitted carry out analysis-by-synthesis, to draw than single signal detection pathological analysis result more accurately.The meaning of conjoint analysis is to utilize the high specific of ultra sonic imaging and the hypersensitivity of UWB electromagnetic wave imaging to carry out complementation, to obtain more detection details and to make pathological analysis more accurately:
At first, ultrasonic signal figure can remedy the deficiency of UWB signal graph: UWB imaging and have hypersensitivity on the accuracy of judgement degree, occur the erroneous judgement situation easily, might draw positive findings to cyst or most of calcification kitchen range.For example, the UWB of cyst imaging might be that the real property of white is block, and is closely similar with tumor imaging, is easy to generate erroneous judgement.And hot spot or light belt can appear in the ultrasonic image of cyst, be easy to distinguish with tumor imaging.Therefore, the high specific of ultra sonic imaging can be made accurate judgement to cyst or calcification kitchen range, thereby reduced the probability of miscarriage of justice of UWB electromagnetic wave signal figure to a certain extent.
In addition, the UWB signal graph also can remedy the deficiency of ultrasonic signal figure on details: generally speaking, around the carcinoid lump the complete fibroid peplos of one deck is arranged, its image boundary is more clearly; And the periphery of malignant tumor lump does not have peplos, or peplos is incomplete, on the traditional medicine image, demonstrates ambiguous border, and generally there is different local edges in the malignant tumor image of different pathological character.Therefore, accurately catch the pathology character that borderline tumor helps to analyze tumor.The high accuracy property that UWB detects can obtain more edge details than ultrasound detection; And can also detect the diffusion trend of cancerous cell, as shown in Figure 2: Fig. 2 a is the ultra sonic imaging sketch map of tumor, and white portion is detected tumor region; Its edge is dim shadow region, and is smudgy; The ash color part is other normal structures; Fig. 2 b is the UWB imaging sketch map of tumor, and white portion is detected tumor region equally, and different is that the shadow region at its edge is more clear than the edge among the ultrasonic figure, bright, more is prone to observe.And can find out that cancerous cell just spreads toward the upper right side.In addition, the hypersensitivity of UWB imaging makes it detect early-stage cancer more easily than ultra sonic imaging.
This shows that ultrasonic signal figure and UWB electromagnetic wave signal figure can be complementary not enough, comprehensive two figure analyze just can make accurately and judge.
The doctor analyzes and makes more accurately and judge that said image association analysis module carries out further Combined Treatment to ultrasonic signal figure and the UWB signal graph that the imaging processing module transmits for ease.The image association analysis module mainly contains two work:
First; In the UWB signal graph, extract the zone that is lower than preset gate limit value TH with ultrasonic signal figure dependency; Form " acoustoelectric signal disparity map "; And be presented on separately on the display, shown in Fig. 2 c: what this figure reflected mainly is the edge configuration of tumor and the spread condition of cancerous cell, can let the doctor that the tumor character is made preliminary analysis and judgement intuitively, fast.
The second, ultrasonic signal figure and UWB signal graph are transformed on " feature space " from " coordinate-gray value space ", the comparison through the characteristic pattern provides more reference information Xiang the doctor.The image association analysis module at first extracts separately eigenvalue CH1, CH2......CHn to two width of cloth gray-scale maps, in identical feature space, forms the characteristic pattern; Calculate the center of gravity O of two characteristic patterns then respectively
1And O
2, and calculate O
1And O
2Distance B in feature space=| O
1-O
2|; Judge whether reliably according to what the value checking of D was made before this at last.Specifically carry out following analysis:
(1) if satisfy D＞Th, then two characteristic pattern similarities are high, and the detection effect basically identical of two paths of signals is described, the analysis of carrying out on this basis will have higher accuracy.
(2) if satisfy Tl＜D＜Th, then two characteristic patterns are similar not high, and instruction book is analyzed from UWB electromagnetic wave image may cause erroneous judgement, points out the doctor to analyze just with reference to ultrasonic signal figure thus and can draw conclusion more accurately.
(3) if satisfy D＜Tl, then two characteristic pattern similarities are very low, explain wherein and one the tunnel detect and possibly make mistakes that the information that these two width of cloth gray-scale maps that draw are provided maybe be unreliable, and the doctor need consider to detect again.(wherein Tl and Th are the threshold values of presetting.)
In sum, said image association analysis module at first forms " acoustoelectric signal disparity map ", lets the doctor that the tumor character is made preliminary assurance intuitively, fast; Then ultrasonic signal figure and the characteristic pattern of UWB signal graph on its feature space are compared, judging whether that checking is this time made is reliable.
Adopt the coded pulse energisation mode to survey and to obtain higher signal to noise ratio.For realizing this function, present embodiment adopts the complementary series sign indicating number as coded pulse sequence.The activation sequence of said encoder output is made up of two 16 complementary series A, B, A={1 wherein, 1,1 ,-1 ,-1 ,-1,1 ,-1 ,-1 ,-1 ,-1,1 ,-1 ,-1,1 ,-1}; B={1,1,1 ,-1 ,-1 ,-1,1 ,-1,1,1,1 ,-1,1,1 ,-1,1}, then activation sequence is C={A; B}={1,1,1 ,-1 ,-1 ,-1,1 ,-1 ,-1 ,-1 ,-1,1 ,-1 ,-1,1 ,-1; 1,1,1 ,-1 ,-1 ,-1,1 ,-1,1,1,1 ,-1,1,1 ,-1,1}.The complementary series sign indicating number has ideal autocorrelation performance, and good autocorrelation performance can guarantee can be formed images clearly after echo-signal is through decoding.
Said detectable signal transceiver module is made up of ultrasonic probe, electromagnetic antenna and the decoder of transmitting-receiving consubstantiality.Ultrasonic probe and electromagnetic antenna are respectively after coded pulse of high frequency complementary series and UWB complementary series coded pulse excitation; Scan to surveyed area simultaneously; Launch high frequency ultrasound detection signal and UWB Electromagnetic Wave Detection signal respectively, and receive echo-signal separately.Because acoustical signal is different with signal of telecommunication physical property, do not disturb mutually, therefore can in same module, transmit and receive simultaneously.Decoder carries out being sent to data acquisition module after the complementary series decoding to the two-way echo-signal.
Said data acquisition equipment is handled respectively the decoded echo-signal of two-way: the detection of echoes signal intensity generates normalized intensity level s; Be data format that ((x, y), two paths of data s) is delivered to the imaging processing module then.
Said imaging processing module utilizes imaging algorithm that the two paths of data that receives is carried out imaging processing respectively, generates about the gray-scale map of ultrasonic signal with about the gray-scale map of electromagnetic wave signal, and two width of cloth gray-scale maps are delivered to the image association analysis module.
As shown in Figure 3, this embodiment adopts following job step:
Step 1, in the signal source stimulating module, the output of high frequency pulse generator produces high-frequency coding pulse excitation sequence through complementary series encoder 1; The output of UWB pulse shaper produces UWB coded pulse activation sequence through complementary series encoder 2.Excitation signals is sent to the detectable signal transceiver module simultaneously.
After ultrasonic probe in step 2, the detectable signal transceiver module and electromagnetic antenna are encouraged, launch high frequency ultrasound pulse sequence signal and UWB electromagnetic impulse sequence signal respectively, simultaneously surveyed area is scanned.
Ultrasonic probe in step 3, the detectable signal transceiver module and electromagnetic antenna receive the echo of high-frequency ultrasonic signal and the echo of UWB electromagnetic wave signal respectively, and two-way echo-signal input decoder is decoded.
Step 4, decoded two paths of signals get into data acquisition module, and this module is handled decoded echo-signal, produce required " coordinate-intensity " data of imaging, and data are delivered to the imaging processing module through two-way.
Step 5, imaging processing module utilize imaging algorithm that the two paths of data that receives is carried out imaging processing respectively, generate about the gray-scale map of ultrasonic signal with about the gray-scale map of electromagnetic wave signal, and two width of cloth gray-scale maps are delivered to the image association analysis module.
Step 6, said image association analysis module carry out conjoint analysis to figure of high-frequency ultrasonic signal and the UWB electromagnetic wave signal figure that the imaging processing module transmits: at first in the UWB signal graph, extract the zone that is lower than preset gate limit value TH with ultrasonic signal figure dependency; Form " acoustoelectric signal disparity map ", let the doctor that the tumor character is made preliminary assurance intuitively, fast; Then ultrasonic signal figure and UWB signal graph are transformed on " feature space " from " coordinate-gray value space "; Form the characteristic pattern; And calculate the distance of geometric center of gravity in feature space of these two characteristic patterns, reliable with judging whether of this time making of this value checking.
As shown in Figure 4, said image association analysis module adopts following job step:
Step 1, in the UWB signal graph, extract the zone that is lower than preset gate limit value TH with ultrasonic signal figure dependency, form " acoustoelectric signal disparity map ", tentatively hold the tumor character.
Step 2, respectively high-frequency ultrasonic signal figure and UWB electromagnetic wave signal figure are carried out feature extraction, calculate its eigenvalue separately: CH1, CH2......CHn.
Step 3, basis eigenvalue generating feature pattern on identical feature space separately (suppose to have 6 characteristics) shown in Fig. 5 a and Fig. 5 b.
The geometric center of gravity O of step 4, two characteristic patterns of calculating
1And O
2, and calculate O
1And O
2Distance B in feature space.
Step 5, further analyze according to the value of D:
(1) if satisfy D＞Th, then two characteristic pattern similarities are high, and the detection effect basically identical of two paths of signals is described, the analysis of carrying out on this basis will have higher accuracy.
(2) if satisfy Tl＜D＜Th, then two characteristic patterns are similar not high, and instruction book is analyzed from UWB electromagnetic wave image may cause erroneous judgement, points out the doctor to analyze just with reference to ultrasonic signal figure thus and can draw conclusion more accurately.
(3) if satisfy D＜Tl, then two characteristic pattern similarities are very low, explain wherein and one the tunnel detect and possibly make mistakes that the information that these two width of cloth gray-scale maps that draw are provided maybe be unreliable, and the doctor need consider to detect again.(wherein Tl and Th are the threshold values of presetting.)
The technical scheme of the present invention is integrated ultrasonic imaging and UWB electromagnetic wave imaging is carried out feature extraction to the echo of two kinds of detectable signals, forms the characteristic pattern, and carries out conjoint analysis.Characteristics of the present invention are: utilize two kinds of physical property various signals to survey, can obtain more target detail, for pathological analysis provides more reference information; Utilize the high specific of ultra sonic imaging and hypersensitivity, the pinpoint accuracy of UWB imaging to carry out complementation, thereby make the pathological analysis result more accurate; Supersonic sounding and electromagnetic wave detection do not disturb mutually, can carry out simultaneously, thus the time cost of saving detecting operation, and the transmitting terminal of two kinds of signals can be integrated in the less module; Adopt coded pulse to survey, can obtain higher signal to noise ratio.
The foregoing description is a preferred implementation of the present invention; But embodiment of the present invention is not restricted to the described embodiments; Other any do not deviate from change, the modification done under spirit of the present invention and the principle, substitutes, combination, simplify; All should be the substitute mode of equivalence, be included within protection scope of the present invention.
Claims (3)
1. one kind is used for the acoustoelectric combined analytical equipment that tumor is surveyed; It is characterized in that comprising the signal source stimulating module that is used for producing simultaneously one road high frequency complementary series coded pulse excitation and one road UWB complementary series coded pulse excitation; Be used for launching high-frequency ultrasonic signal and UWB electromagnetic wave signal simultaneously and receive the detectable signal transceiver module that echo carries out sending to after complementary series is decoded data acquisition module; The data acquisition module that is used to gather the decoded echo-signal of two-way and produces imaging data; Be used to generate about the gray-scale map of ultrasonic signal and about the gray-scale map of electromagnetic wave signal and with two width of cloth gray-scale maps deliver to the imaging processing module of image association analysis module and be used for to two width of cloth figure carry out difference extract with feature extraction after formation characteristic pattern and make the image association analysis module of pathological analysis; Said signal source stimulating module, detectable signal transceiver module, data acquisition module, imaging processing module and image association analysis module are connected in order.
2. analytical equipment according to claim 1; It is characterized in that said signal source stimulating module comprises the high-frequency impulse formation device and the first complementary series encoder that is used to produce high frequency complementary series coded pulse excitation, also comprise being used to produce UWB complementary series coded pulse excitation other the UWB pulse shaper and the second complementary series encoder.
3. analytical equipment according to claim 1; It is characterized in that said detectable signal transceiver module comprises the ultrasonic probe that is used for after high frequency complementary series coded pulse excitation, launching the high frequency ultrasound detection signal and receives echo-signal; Be used for through UWB complementary series coded pulse excitation back emission UWB Electromagnetic Wave Detection signal and receive the electromagnetic antenna of echo-signal and be used for the two-way echo-signal is carried out being sent to after complementary series is decoded the decoder of data acquisition module.
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| CN2011203055830U Withdrawn - After Issue CN202211713U (en) | 2011-08-22 | 2011-08-22 | Acoustoelectric conjoint analysis device for detecting tumors |
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| CN (1) | CN202211713U (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102266240A (en) * | 2011-08-22 | 2011-12-07 | 华南理工大学 | Acoustic-electric joint analysis device used for tumor detection |
| CN107510456A (en) * | 2017-08-17 | 2017-12-26 | 佛山市丈量科技有限公司 | A kind of radio frequency sensor and sensor array suitable for wearable intelligent dress ornament |
-
2011
- 2011-08-22 CN CN2011203055830U patent/CN202211713U/en not_active Withdrawn - After Issue
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102266240A (en) * | 2011-08-22 | 2011-12-07 | 华南理工大学 | Acoustic-electric joint analysis device used for tumor detection |
| CN107510456A (en) * | 2017-08-17 | 2017-12-26 | 佛山市丈量科技有限公司 | A kind of radio frequency sensor and sensor array suitable for wearable intelligent dress ornament |
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