CN202136447U - Degradable rack for sternal coloboma repair - Google Patents

Degradable rack for sternal coloboma repair Download PDF

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Publication number
CN202136447U
CN202136447U CN201120242711U CN201120242711U CN202136447U CN 202136447 U CN202136447 U CN 202136447U CN 201120242711 U CN201120242711 U CN 201120242711U CN 201120242711 U CN201120242711 U CN 201120242711U CN 202136447 U CN202136447 U CN 202136447U
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China
Prior art keywords
rack
rib
draw
groove
degradable
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Expired - Lifetime
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CN201120242711U
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Chinese (zh)
Inventor
唐华
徐志飞
薛磊
季明明
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Individual
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Individual
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Expired - Lifetime legal-status Critical Current

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Abstract

A degradable rack for sternal coloboma repair belongs to the technical field of biomedicine. The degradable rack for sternal coloboma repair is characterized in that the rack is crossed; clamping slots which are flat, solid, enclosed around and open at the front end are arranged at the four crossed ends; a sternum clamping slot is formed in the longitudinal direction; a rib clamping slot is formed in the transverse direction; and the contours of the inner cavities of the sternum clamping slot and the rib clamping slot are similar to the shapes of the sternum and the rib. The degradable rack for sternal coloboma repair has the benefits as follows: since the rack is made of degradable materials, the rack stimulates tissues weakly and provides high infection resistance; due to the unique personalized design, the rack can recover the biological form and functionality of the receptor to the greatest extent; and the rack eliminates the complexity and difficulty of conventional operations, shortens operation time and improves operation efficiency.

Description

A kind of biodegradable stent that is used for the breastbone defect repair
Technical field
Belong to the biological medicine technology field, relate to the technology of breastbone defect repair treatment, specifically a kind of biodegradable stent that is used for the breastbone defect repair.
Background technology
Breastbone is the flat bone that is positioned at front wall center, and the likeness in form dirk divides three ones of handles, body, xiphoid-process.The breastbone both sides are connected with rib, constitute thorax, make important function to protecting in vertical diaphragm and the thoracic cavity internal organs to rise.Because breastbone common diseases such as breastbone tumor, infection, radiation ulcer, wound and congenital malformation; Often need operative treatment; Thereby cause the damaged of breastbone, the integrity of thorax, stability and the protectiveness of vertical diaphragm internal organs destroyed, jeopardizes patient's life.Breastbone needs to rebuild, and method for reconstructing and the material of using breastbone at present are more, but many corresponding shortcomings are all arranged, and the surgical repair effect is undesirable.
The domestic and international at present research to Sternal reconstruction is not a lot; Mainly accomplish Sternal reconstruction with reference to thoracic wall rib absence method for reconstructing; The method of repairing is more: allograph bone, autologous bone transplanting, muscle flap, flap, omentum majus, steel plate, lucite, wire netting, tinsel, synthetic fibers, politef net, titanium net, silicone rubber plate, Marlex net and woven dacron, bone cement etc. are arranged; Effect is uneven, and first brief account is following:
1, autologous tissue. have wide material sources, draw materials conveniently, histocompatibility is good, no foreign body reaction, the patient is easy to accept that good holding power is arranged, and can prevent that thoracic wall from floating to reach paradoxical breathing; " can place for a long time in the body, not become flexible; And can see through advantages such as X line; But shortcoming be draw materials limited; Tensile strength is not enough; Destroy other organizational structure and cause operation wound. so be used for the less defect repair of area and flap filling and transfer more; Also can combine artificial material reparation in addition. commonly used clinically pectoralis major, pectoralis major island skin flap, mammary gland, rectus abdominis m., rectus abdominis m. musculo cutaneous flap (TRAM), latissimus dorsi m., latissimus dorsi myocutaneous flap, serratus anterior, diaphram, omentum majus are arranged, from body rib, iliotibial tract etc. the quality from the body bone is depended in the success of bone grafting to a great extent, and the blood of implant bed supplies and has the abundant soft tissue of blood fortune to cover.Enough fixing also must be arranged in addition, and the shears of eliminating between soft tissue and the bone grafting is movable, helps new vessels and grows into, and requirements of operation is high, and difficulty is big.And the many deflections of the reparation of autologous tissue are to the coverings of defect, and hard conditions to satisfy the aspect undesirable.Large-area damaged, autologous tissue repairs inadequate slightly, and operation is drawn materials and also increased patient's misery.
2, artificial material. of a great variety, mainly contain steel plate, titanium plate, poly (methyl methacrylate) plate, steel wire etc. in early days, but the histocompatibility of this type material is poor; Be difficult to fixing and be prone to become flexible, be difficult for moulding and cutting, metal material particularly metallic plate can influence postoperative X ray examination and radiotherapy; So abandoned in recent years using. the reparation of bone property thoracic wall adopts bone cement and/or autologous tissue's material to unite reconstruction more in the world at present. and the compatibility of this type material structure is better, and the moulding convenience of cutting is convenient to sterilization; Do not influence postoperative X ray examination and radiotherapy; But still exist pliability poor, and and organize adaptation not good, tensile strength is not enough; Size is less than normal, limited and shortcoming such as cost an arm and a leg on large-area defect repair.Hyans etc. select for use the politef sticking patch to repair, and to solve the problem of sticking patch and lung tissue adhesion, have obtained some progress.In recent years use MMA (methacrylic resin) obtained certain progress; The MMA cured strength is big, stability is strong; Ductility is strong before solidifying, the good histocompatibility of plasticity is good, and foreign body reaction is low weight, has reduced the filling place infection of operation back, hydrops odds; The X line has fabulous penetrance to MMA, does not influence the X ray examination behind the repairing chest wall defect.But MMA has stronger exothermic reaction when moulding, the perienchyma that burns easily, and in addition, charges can carry out anion exchange with contiguous lung tissue, and metabolic acidosis possibly appear in patient.
3, biomaterial is taken from animal tissue more, and it is satisfied to be like: bud use self-control bovine pericardium+steel wire such as power is repaired 9 routine chest wall defect effects; Have also that to adopt pig be that organization material is originated, generally speaking, the biomaterial pliability is good; Wide material sources, stretching resistance is strong, is difficult for aging; Preparation is preserved convenient. and shortcoming is to have antigenicity, is prone to produce repel, and then stretching resistance is not enough as not carrying out modification.
Summary of the invention
This utility model provides that a kind of wound is little, easy and simple to handle, the material degradable, fixed, do not need a kind of biodegradable stent that is used for the breastbone defect repair of performing the operation once more and taking out.
The technical scheme that this utility model is taked::
A kind of biodegradable stent that is used for the breastbone defect repair comprises the connection draw-in groove that connects breast, rib, and its scheme is: support is a crosswise; Criss-cross four ends are flat formula, inner real core, the draw-in groove of sealing, front opening all around; Vertical draw-in groove of cross frame is the breastbone draw-in groove, breastbone draw-in groove inner chamber profile and breastbone appearance similar; The horizontal draw-in groove of cross frame is the rib draw-in groove, rib draw-in groove inner chamber profile and rib appearance similar.
Good effect behind enforcement this utility model is:
Since the support that the Biodegradable material that has used polycaprolactone and hydroxyapatite to constitute is processed, so this support is little for the zest of tissue, and anti-infection ability is stronger; In addition, its unique personalized design can be recovered form and function biology of receptor to greatest extent; Substitute part by utilizing the quiet free manufacturing technology of fusion to form after polycaprolactone and the hydroxyapatite blend by a certain percentage for utilizing the quiet free manufacturing technology of fusion to form after the ratio blend with the duplicate breast of individual part to be repaired, rib with the duplicate breast of individual part to be repaired, rib; The complexity and the difficulty of operation have in the past been avoided; Shorten operating time, improved operation efficient.
Description of drawings
Fig. 1, be used for the biodegradable stent of breastbone defect repair,
The application sketch map of Fig. 2, biodegradable stent.
The specific embodiment
Combine accompanying drawing that this utility model is described further at present,
A kind of biodegradable stent that is used for the breastbone defect repair comprises the connection draw-in groove that connects breast, rib, and its structure is: biodegradable stent 1 is crosswise; Criss-cross four ends are flat formula, inner real core, the draw-in groove of sealing, front opening all around; Vertical draw-in groove of cross frame is a breastbone draw-in groove 2, breastbone draw-in groove inner chamber profile and breastbone appearance similar; The horizontal draw-in groove of cross frame is a rib draw-in groove 3, rib draw-in groove inner chamber profile and rib appearance similar.
Embodiment
Is to mix at 30%: 70% hydroxyapatite and PCL by mass ratio, and fusion on the Haake torque rheometer.With the quiet free manufacturing technology of the material use fusion behind the melt blending by individuation requirement molding.Then that it is subsequent use with oxirane disinfection.
Select healthy new zealand white rabbit dog, behind general intravenous anesthesia, tracheal intubation, mechanical ventilation is all bitten rib broken from about 1 centimeters of breastbone, removes breastbone, and the breastbone prosthesis is implanted, and fixes with the rib stub, successively closes breast.
Embodiment result:
All White Rabbit postoperatives are all survived, and dyspnea does not appear in circulatory failure, and the thorax profile is satisfied.Respectively at postoperative 2,4, the CT examination of going in 8,12,24 weeks shows that rib is fixed well, and keeps existing breastbone form, and the broken ends of fractured bone all heals basically when 12 weeks, and bad late complication does not appear in internal fixation material degraded 70% when 24 weeks.We find that this material does not influence X sheet and the CT observation for internal organs in the thorax in addition.

Claims (1)

1. a biodegradable stent that is used for the breastbone defect repair comprises the connection draw-in groove that connects breast, rib, and it is characterized in that: biodegradable stent (1) is a crosswise; Criss-cross four ends are flat formula, inner real core, the draw-in groove of sealing, front opening all around; Vertical draw-in groove of cross frame is breastbone draw-in groove (2), breastbone draw-in groove inner chamber profile and breastbone appearance similar; The horizontal draw-in groove of cross frame is rib draw-in groove (3), rib draw-in groove inner chamber profile and rib appearance similar.
CN201120242711U 2011-07-11 2011-07-11 Degradable rack for sternal coloboma repair Expired - Lifetime CN202136447U (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201120242711U CN202136447U (en) 2011-07-11 2011-07-11 Degradable rack for sternal coloboma repair

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201120242711U CN202136447U (en) 2011-07-11 2011-07-11 Degradable rack for sternal coloboma repair

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CN202136447U true CN202136447U (en) 2012-02-08

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102240233A (en) * 2011-07-11 2011-11-16 唐华 Degradable stent for sternum defect repair and manufacturing method thereof

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102240233A (en) * 2011-07-11 2011-11-16 唐华 Degradable stent for sternum defect repair and manufacturing method thereof
CN102240233B (en) * 2011-07-11 2015-03-25 唐华 Degradable stent for sternum defect repair and manufacturing method thereof

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C14 Grant of patent or utility model
GR01 Patent grant
AV01 Patent right actively abandoned

Granted publication date: 20120208

Effective date of abandoning: 20150325

RGAV Abandon patent right to avoid regrant