CN202105203U - Sticking membrane for dermatosis and ulcer wound surface - Google Patents
Sticking membrane for dermatosis and ulcer wound surface Download PDFInfo
- Publication number
- CN202105203U CN202105203U CN2011201293660U CN201120129366U CN202105203U CN 202105203 U CN202105203 U CN 202105203U CN 2011201293660 U CN2011201293660 U CN 2011201293660U CN 201120129366 U CN201120129366 U CN 201120129366U CN 202105203 U CN202105203 U CN 202105203U
- Authority
- CN
- China
- Prior art keywords
- wound surface
- sticking membrane
- parts
- ulcer wound
- dermatosis
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Images
Abstract
The utility model relates to a sticking membrane for a dermatosis and an ulcer wound surface, which comprises a backing layer, a matrix layer and a protective layer. The backing layer and the protective layer are respectively arranged on two surfaces of the matrix layer. The sticking membrane has the advantages that the sticking membrane has high moisture content, strong moisture retention, good air permeability, large drug loading rate and suitable adhesion ability, has good effects of protecting the wound surface and promoting penetration and adsorption, has no irritation on the skin and the ulcer wound surface and has high safety; and the using range of the sticking membrane with high moisture content is expanded, so that the sticking membrane not only can be used for external application to the normal skin but also can be used for the ulcer wound surface, a novel treatment method and an approach are found for the healing of the wound surface, and wider application prospect is developed for the sticking membrane with high moisture content.
Description
Technical field
This utility model relates to medical external pad pasting field, specifically, is that a kind of height that is used for dermatosis and ulcer wound surface contains water adhered film.
Background technology
Along with in recent years, the high speed development of hydrophilic macromolecule bioadhesive material, the mesh skeleton structure and the high property of water-bearing that it is unique more and more receive people's welcome, and especially the research at cosmetic field obtains huge achievement.But show slightly hysteresis in medical domain research; At present, skin ulcer, dermatosis are common clinical, frequently-occurring disease, and the external used medicine dosage form of clinical middle treatment skin ulcer is different; Like powder, ointment etc.; Curative effect has nothing in common with each other, and these dosage form preparation standards can't unify, and therapeutic effect often can not be satisfactory.Externally used pad pasting belongs to a kind of of transdermal drug delivery system or transdermal formulation, can carry various multi-form medicines, big because of its drug loading, have no side effect, advantage such as good permeability, obtain medical circle gradually and extensively welcome.But, select appropriate hydrophilic high molecular material, suitable proportioning to adapt to skin ulcer wound surface and various treating for skin disease, reaches non-stimulated to ulcer wound surface and skin, water content is high, short oozing property is good, hold purposes such as dose is big, still is a great problem.
Chinese patent publication number CN101053555B discloses a kind of catablasm base material and preparation method thereof, and its prescription is Ka Baimu 2.0-10.0 part, arabic gum 5.0-20.0 part, glycerol 20.0-60.0 part; Polyethylene Glycol 3.0-10.0 part, polyvidone 10.0-40.0 part, gelatin 10.0-40.0 part; Sodium hydroxide 1.0-4.0 part, ultra-pure water 70.0-120.0 part, azone 0.0-6.0 part; Camphora 0.0-5.0 part, Mentholum 0.0-5.0 part or azone 0.0-6.0 part, Fructus Capsici extract 0.0-5.0 part.Chinese patent publication number CN101485680A discloses a kind of compound magnesium sulphate catablasm and preparation method thereof, comprises backing layer, medicine drug storage layer and adherent layer three parts, and wherein the medicine in the drug storage layer is 3.0-10.0 part magnesium sulfate and 2.0-5.0 part lidocaine hydrochloride; Substrate is Ka Baimu 2.0-10.0 part, arabic gum 5.0-20.0 part, glycerol 20.0-60.0 part; Polyethylene Glycol 3.0-10.0 part; Polyvidone 5.0-10.0 part, gelatin 10.0-40.0 part, sodium hydroxide 1.0-4.0 part; Mentholum 0.5-3.0 part, purified water 70-100 part.But containing water adhered film about the height that is used for dermatosis and ulcer wound surface does not also appear in the newspapers at present.
Summary of the invention
The purpose of this utility model is that a kind of pad pasting that is used for dermatosis and ulcer wound surface is provided.
For realizing above-mentioned purpose; The technical scheme that this utility model is taked is: a kind of pad pasting that is used for dermatosis and ulcer wound surface; Comprise backing layer, hypothallus and protective layer; Described backing layer and protective layer lay respectively at the two sides of hypothallus, and described hypothallus is processed by the raw material of following weight portion: polyvidone 5-10 part, gelatin 10-20 part, carbomer 5-10 part, Polyethylene Glycol 1-5 part, glycerol 30-50 part, micropowder silica gel 5-20 part, zinc oxide 3-10 part, sodium hydroxide 2-10 part, azone 2-10 part, purified water 35-55 part, Borneolum Syntheticum 2-10 part.
Described backing layer is processed by non-woven fabrics.
Described protective layer is processed by cellophane or plastic sheeting.
The method for preparing of described pad pasting may further comprise the steps:
1. polyvidone, gelatin are dissolved in 65 ° of purified water, keep heating for dissolving in the 60-70 ° of water-bath, and behind the stirring 30-60min, fully swelling gets mixture a;
2. carbomer, Polyethylene Glycol, glycerol are heated to 70 ° and stir the 30min uniform mixing, and is subsequent use;
3. heated and stirred during 2. micropowder silica gel, zinc oxide, sodium hydroxide, purified water add gets mixture b;
Insert mixture a when 4. mixture b is heated to 50 ° and stir, the back adds Borneolum Syntheticum, azone, Western medicine or Chinese medicine extract, stirs 30 minutes mixings, promptly gets hypothallus;
5. hypothallus was put in the film machine, and backing layer non-woven fabrics and protective layer plastic sheeting cover about the hypothallus, and the pad pasting of the size shape that cutting needs packages spare.
This utility model advantage is:
1, this pad pasting water content is high, moisture retention strong, good permeability, hold that dose is big, adhesiveness suitable, has the effect of better protect wound surface and preferable short imbibition adduction, and is non-stimulated to skin and ulcer wound surface, safe;
2, expanded the high scope of application that contains water adhered film, made its external that not only is confined to normal skin, and be extended to the use of ulcer wound surface,, developed the better application prospect for height contains water adhered film for a kind of new Therapeutic Method and means have been found in the healing of wound surface.
Description of drawings
Accompanying drawing 1 is a kind of structural representation that is used for the pad pasting of dermatosis and ulcer wound surface of this utility model.
The specific embodiment
Below in conjunction with embodiment and with reference to accompanying drawing this utility model is further described.
The Reference numeral and the ingredient that relate in the accompanying drawing are as follows:
1. backing layer 2. hypothalluses
3. protective layer
Please with reference to accompanying drawing 1, accompanying drawing 1 is a kind of structural representation that is used for the pad pasting of dermatosis and ulcer wound surface of this utility model.Described pad pasting is made up of backing layer 1, hypothallus 2 and protective layer 3.Described backing layer 1 is processed by medical non-woven fabrics with good permeability of anti-reverse osmosis effect, can prevent drug extravasation effectively, reduces drug waste.Hypothallus 2 is formed according to specific processes by multiple hydrophilic high molecular material, have non-stimulated to skin ulcer wound surface and skin, water content is high, short oozing property is good, bioavailability is high, hold advantages such as dose is big.Protective layer 3 is to be processed by cellophane or plastic sheeting, prevents that medicine and packing adhesion from causing waste.
The preparation (one) of embodiment 2 pad pastings
Form: 5 parts of polyvidones, 10 parts in gelatin, 5 parts of carbomers, 1 part of Polyethylene Glycol, 30 parts of glycerol, 5 parts of micropowder silica gels, 3 parts of zinc oxide, 2 parts of sodium hydroxide, 2 parts of azones, 35 parts of purified water, 2 parts of Borneolum Syntheticums.
Processing technology:
(1) polyvidone, gelatin are dissolved in 65 ° of purified water, keep heating for dissolving in the 60-70 ° of water-bath, and behind the stirring 30-60min, fully swelling gets mixture a;
(2) carbomer, Polyethylene Glycol, glycerol are heated to 70 ° and stir the 30min uniform mixing, and is subsequent use;
(3) micropowder silica gel, zinc oxide, sodium hydroxide, purified water add heated and stirred in (2), get mixture b;
Insert mixture a when (4) mixture b is heated to 50 ° and stir, the back adds Borneolum Syntheticum, azone, Western medicine or Chinese medicine extract, stirs 30 minutes mixings, promptly gets hypothallus 2;
(5) hypothallus 2 was put in the film machine, and backing layer 1 non-woven fabrics and protective layer 3 plastic sheetings cover hypothallus about in the of 2, and the pad pasting of the size shape that cutting needs packages spare.
The preparation (two) of embodiment 3 pad pastings
Form: 10 parts of polyvidones, 20 parts in gelatin, 10 parts of carbomers, 5 parts of Polyethylene Glycol, 50 parts of glycerol, 20 parts of micropowder silica gels, 10 parts of zinc oxide, 10 parts of sodium hydroxide, 10 parts of azones, 55 parts of purified water, 10 parts of Borneolum Syntheticums.
Processing technology:
(1) polyvidone, gelatin are dissolved in 65 ° of purified water, keep heating for dissolving in the 60-70 ° of water-bath, and behind the stirring 30-60min, fully swelling gets mixture a;
(2) carbomer, Polyethylene Glycol, glycerol are heated to 70 ° and stir the 30min uniform mixing, and is subsequent use;
(3) micropowder silica gel, zinc oxide, sodium hydroxide, purified water add heated and stirred in (2), get mixture b;
Insert mixture a when (4) mixture b is heated to 50 ° and stir, the back adds Borneolum Syntheticum, azone, Western medicine or Chinese medicine extract, stirs 30 minutes mixings, promptly gets hypothallus 2;
(5) hypothallus 2 was put in the film machine, and backing layer 1 non-woven fabrics and protective layer 3 plastic sheetings cover hypothallus about in the of 2, and the pad pasting of the size shape that cutting needs packages spare.
The preparation (three) of embodiment 4 pad pastings
Form: 8 parts of polyvidones, 15 parts in gelatin, 8 parts of carbomers, 3 parts of Polyethylene Glycol, 40 parts of glycerol, 10 parts of micropowder silica gels, 7 parts of zinc oxide, 6 parts of sodium hydroxide, 6 parts of azones, 45 parts of purified water, 6 parts of Borneolum Syntheticums.
Processing technology:
(1) polyvidone, gelatin are dissolved in 65 ° of purified water, keep heating for dissolving in the 60-70 ° of water-bath, and behind the stirring 30-60min, fully swelling gets mixture a;
(2) carbomer, Polyethylene Glycol, glycerol are heated to 70 ° and stir the 30min uniform mixing, and is subsequent use;
(3) micropowder silica gel, zinc oxide, sodium hydroxide, purified water add heated and stirred in (2), get mixture b;
Insert mixture a when (4) mixture b is heated to 50 ° and stir, the back adds Borneolum Syntheticum, azone, Western medicine or Chinese medicine extract, stirs 30 minutes mixings, promptly gets hypothallus 2;
(5) hypothallus 2 was put in the film machine, and backing layer 1 non-woven fabrics and protective layer 3 plastic sheetings cover hypothallus about in the of 2, and the pad pasting of the size shape that cutting needs packages spare.
Need to prove that the height of this utility model contains water adhered film and has following characteristic:
1, expanded the high scope of application that contains water adhered film: the application that this utility model makes height contain water adhered film not only is confined to the external of normal skin; And be extended to the use of ulcer wound surface; For a kind of new Therapeutic Method and means have been found in the healing of wound surface,, height develops better prospect for containing water adhered film;
2, safe, non-stimulated to skin and ulcer wound surface: the maximum difference of this utility model and other pad pastings is to adopt water-soluble high-molecular compound or hydrophilic high molecular material, animals and plants extract as substrate; So make itself and skin and ulcer wound surface that the compatibility preferably, affinity arranged; Nonirritant and sensitization, painless in the use; Can not produce reactions such as pruritus, twinge, use comfortablely, patient experiences is good;
3, water content is high, moisture retention is strong: the height of this utility model preparation contains water adhered film and has tangible honeycomb framing structure, and mostly raw material be hydrophilic high molecular material, and water content reaches more than 55%, has higher water content and moisture retention;
4, good permeability: the height of this utility model preparation contain water adhered film with non-woven fabrics with reverse osmosis effect as backing layer; Not only prevent drug extravasation effectively; Reduce drug waste, and combine the honeycomb framing structure of this pad pasting, guaranteed this utility model air permeability and good;
5, the effect of better protect wound surface: this height contains water adhered film and is the basis with moist environment healing theory; This height contains water adhered film and has breathability, wettability, flexibility preferably; Can protect wound surface better, avoid air pollution, reduce the probability that infects; Avoid the stimulation of external environment and exposing of teleneuron, reduce the generation of pain preferably;
6, preferable short imbibition adduction: the height of this utility model preparation contains water adhered film; With its unique high property of water-bearing, moisture retention; Under the short effect of oozing of azone, Borneolum Syntheticum, can guarantee the lasting absorption of medicine, not only promoted the circulation of agents area to absorb; Also be beneficial to medicine and get into the blood lymph circulation, guaranteed medication local curative effect improve with whole; And Borneolum Syntheticum also has certain antibacterial anti-inflammatory effect, so prevented also that to a certain extent medicine is rotten; Promote the targeting property of external used medicine absorption, the effectiveness of raising medicine;
7, it is big to hold dose: have the honeycomb framing structure because the height of this utility model preparation contains water adhered film, can carry more interpolation medicine, the 3-5 that can reach traditional external use plaster doubly; Onset is rapid; The most important thing is, can guarantee that the original appearance of adding medicine is not destroyed, and the long-time continuous administration; Thereby keep the blood drug level of necessary level, more help bringing into play the effect of medicine;
8, suitable adhesiveness: this height contains water adhered film; Adopt the mixture of glycerol, gelatin, micropowder silica gel to form, guaranteed and added the adhesiveness of medicine, but avoided the use of high-adhesiveness things such as the stronger methylcellulose of viscosity, sodium polyacrylate; Make the softish suitable adhesiveness that has; Reduced stimulation, sticked and removed in the process painless seamless, be suitable for the use of various wound surface and skin wound surface and skin.
The above only is the preferred implementation of this utility model; Should be pointed out that for those skilled in the art, under the prerequisite that does not break away from this utility model principle; Some improvement be can also make and these improvement and the additional protection domain that also should be regarded as this utility model replenished.
Claims (3)
1. a pad pasting that is used for dermatosis and ulcer wound surface comprises backing layer, hypothallus and protective layer, it is characterized in that, described backing layer and protective layer lay respectively at the two sides of hypothallus.
2. pad pasting according to claim 1 is characterized in that described backing layer is processed by non-woven fabrics.
3. pad pasting according to claim 1 is characterized in that described protective layer is processed by cellophane or plastic sheeting.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2011201293660U CN202105203U (en) | 2011-04-28 | 2011-04-28 | Sticking membrane for dermatosis and ulcer wound surface |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2011201293660U CN202105203U (en) | 2011-04-28 | 2011-04-28 | Sticking membrane for dermatosis and ulcer wound surface |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN202105203U true CN202105203U (en) | 2012-01-11 |
Family
ID=45430657
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN2011201293660U Expired - Fee Related CN202105203U (en) | 2011-04-28 | 2011-04-28 | Sticking membrane for dermatosis and ulcer wound surface |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN202105203U (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103495155A (en) * | 2013-09-25 | 2014-01-08 | 南阳市汇博生物技术有限公司 | Film for hyperplastic scar repair and preparation method thereof |
-
2011
- 2011-04-28 CN CN2011201293660U patent/CN202105203U/en not_active Expired - Fee Related
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103495155A (en) * | 2013-09-25 | 2014-01-08 | 南阳市汇博生物技术有限公司 | Film for hyperplastic scar repair and preparation method thereof |
| CN103495155B (en) * | 2013-09-25 | 2015-10-14 | 南阳市汇博生物技术有限公司 | For pad pasting that hypertrophic cicatrix is repaired and preparation method thereof |
| CN105250995A (en) * | 2013-09-25 | 2016-01-20 | 南阳市汇博生物技术有限公司 | Hyperplastic scar repair plaster and preparing method thereof |
| CN105250995B (en) * | 2013-09-25 | 2018-06-22 | 河南汇博医疗股份有限公司 | Hyperplastic scar repairs pad pasting and preparation method thereof |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| AU2014270116B2 (en) | Transdermal delivery system | |
| ES2387804T3 (en) | Methods of administration a dermatological agent to a subject | |
| AU2014270115B2 (en) | Dressing system | |
| SK12962002A3 (en) | Intradermal-penetration agents for topical local anesthetic administration | |
| CN105903068A (en) | Medical composite chitosan gel containing analgesic drug | |
| TW201201796A (en) | Transdermal delivery patch | |
| CN102218074B (en) | Transdermal patch containing paeoniflorin and glycyrrhetinic acid and method for preparing same | |
| US20130224280A1 (en) | Transdermal compositions and methods for treating stretch marks | |
| WO2016079538A1 (en) | Dressing system | |
| EP2697492B1 (en) | Transdermal patches having ionized beam crosslinked polymers and improved release characteristics | |
| CN103623453A (en) | Preparation method of silver ion hydrogel dressing | |
| CN100534421C (en) | Hydrophillia Babu agent for treating depression | |
| CN202105203U (en) | Sticking membrane for dermatosis and ulcer wound surface | |
| CN102366444A (en) | Cooling patch and preparation method thereof | |
| CN107375994A (en) | A kind of medical gel adhesive bandage product preparation method | |
| CN1861059A (en) | Hydrophilic gel type percutaneous plaster contg. capsaicin, and its prepn. method | |
| CN106937942A (en) | A kind of medical skin wound analgesia gel and preparation method thereof | |
| CN101627979B (en) | Estradiol transdermal slow-release paster | |
| CN203042644U (en) | Aloe wound paste | |
| CN107789660A (en) | It is a kind of to be used for skin and the medical dressing of soft tissue injury | |
| CN116509823B (en) | Ketorolac tromethamine gel plaster composition, gel plaster and preparation method thereof | |
| CN219000871U (en) | Hyaluronic acid hydrogel application | |
| CN202052059U (en) | Microporous transdermal patch | |
| CN105963281A (en) | Chitin scar-restraint gel coating as well as preparation method and application thereof | |
| CN106466309A (en) | A kind of radiation-induced skin ulcer nursing emulsifiable paste and preparation method thereof |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20120111 Termination date: 20150428 |
|
| EXPY | Termination of patent right or utility model |