CN202060796U - Prostate transrectal ultrasound and nuclear magnetic resonance (NMR) images fusion intracavity registering device - Google Patents
Prostate transrectal ultrasound and nuclear magnetic resonance (NMR) images fusion intracavity registering device Download PDFInfo
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- CN202060796U CN202060796U CN 201120149821 CN201120149821U CN202060796U CN 202060796 U CN202060796 U CN 202060796U CN 201120149821 CN201120149821 CN 201120149821 CN 201120149821 U CN201120149821 U CN 201120149821U CN 202060796 U CN202060796 U CN 202060796U
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- magnetic resonance
- nuclear magnetic
- transrectal ultrasound
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- prostate
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Abstract
The utility model relates to a prostate transrectal ultrasound and nuclear magnetic resonance (NMR) images fusion intracavity registering device which is provided with a carrier, a bracket, an adjusting device and a base, wherein the carrier is arranged on the bracket; the bracket is connected with the base through the adjusting device; and labels are arranged in the carrier. The utility model has the advantages that the device is simple and convenient, accurate and fast in registering prostate transrectal ultrasound and NMR images, and the registering is realized by only registering layer surfaces which contain an identical number of labels under two imaging modes; the prostate transrectal ultrasound and NMR images fusion intracavity registering device does no damage to patients and has no need to implant labels in the body of the patients so as to avoid damage and use limitation; the can be repeatedly used for multiple times by only changing the labels at a time, and various labels can be selected and can be selected according to conditions, therefore, the device has a wide application range; and the device has small and exquisite volume has good patient tolerance and high degree of approval, and the diameter is equal to that of the traditional transrectal ultrasound probe.
Description
Technical field
This utility model relates to the image registration field, specifically, is registration apparatus in a kind of prostate Transrectal Ultrasound and the nuclear magnetic resonance image fusion chamber.
Background technology
In the image registration of prostate NMR (Nuclear Magnetic Resonance)-imaging (MRI) and Transrectal Ultrasound imaging (TRUS) was merged with guiding aspiration biopsy of prostatic gland process, the conventional images registration technique mainly comprised:
1, implants intraprostatic radioactive particle as the image registration label with the prostate brachytherapy;
2, edge contour or the intraprostatic relevant focus with prostate self contour feature and anatomic landmark, prostate and transitional areas thereof such as pixel characteristic, intraprostatic calcification, internal urethral orifice is the image registration internal markers;
3, by magnetic field generator, be integrated with the ultrasonic probe of following the tracks of sensor and have the electromagnetism spike navigation system that the work station of related software forms and carry out the image registration fusion.
Yet there are many deficiencies in the conventional images registration technique:
1, implants intraprostatic radioactive particle as the image registration label with the prostate brachytherapy, to before imaging, place by invasive technique in advance, can cause in various degree damage to the patient, and suitable crowd is confined to the patient that carcinoma of prostate is accepted brachytherapy, is unfavorable for large-scale clinical application;
2, edge contour or the intraprostatic relevant focus with prostate self contour feature and anatomic landmark, prostate and transitional areas thereof such as pixel characteristic, intraprostatic calcification, internal urethral orifice is the image registration internal markers, need the operator that these signs are carried out accurate recognition, the artificial subjective factor influence is bigger; In addition, since the internal diameter of the pressure that the bladder of different filling degrees and rectum form, patient body position, endorectal ultrasonography probe and nuclear magnetic resonance, NMR (MR) rectum coil is inconsistent and intervention procedure in the formed pressure of insertion of biopsy needle, these factors all can cause prostate to produce in various degree displacement and deformation, rely on prostate geometric shape and local point, line, surface this moment, to show that contour feature etc. carries out the method error of registration just very big.
3, electromagnetism spike navigation system is carried out the image registration fusion needs label to merge under the prerequisite of starting point aspect registration (initialization), and there are above-mentioned 1 and 2 described weak points equally in the required label of starting point aspect registration.
Chinese patent application CN 201578259U, open day be JIUYUE in 2010 15 days, the utility model name is called a kind of multi-mode image registration auxiliary device, this utility model provides a kind of multi-mode image registration auxiliary device, comprising: base plate: have first of spatial accommodation and hold body, second and hold body and the 3rd and hold body; Described first holds body, second holds body and the 3rd and holds the surface that body all is fixedly set in described base plate, and protrudes in the surface of described base plate.This utility model complex structure, and can only carry out registration process to external image, the scope of application is limited, can not carry out accurate aspiration biopsy to carcinoma of prostate etc.
Because the aspiration biopsy of prostatic gland art of Transrectal Ultrasound guiding and pathological diagnosis are the goldstandards of diagnosing prostate cancer before the clinic operation, therefore, need badly want a kind of can be to conventional ultrasonic examination driftlessness but other imaging examination (as NMR (Nuclear Magnetic Resonance)-imaging) has the carcinoma of prostate focus of hard objectives to carry out the image co-registration registration apparatus of accurate aspiration biopsy, but, yet there are no report about this device.
Summary of the invention
The purpose of this utility model is that registration apparatus in a kind of prostate Transrectal Ultrasound and the nuclear magnetic resonance image fusion chamber is provided.
For achieving the above object, the technical scheme that this utility model is taked is: registration apparatus in a kind of prostate Transrectal Ultrasound and the nuclear magnetic resonance image fusion chamber, be provided with carrier, support, adjusting device and base, described carrier is located on the support, support is connected with base by adjusting device, is provided with label in the described carrier.
Described carrier becomes hollow cylindrical, and carrier is provided with bond site and ultrasonic scanning window position.
Described ultrasonic scanning window position is provided with blind cylindrical hole.
It is capable that described blind cylindrical hole is provided with 3-9, and the row distance of center circle is 2～20mm, and blind cylindrical hole is along the parallel distribution of carrier face of cylinder long axis direction.
Described blind cylindrical hole diameter is the 1-5 millimeter, blind cylindrical hole hole depth 1-5 millimeter, hole base thickness 0.1-5 millimeter.
Put up hollow cylindrical for described, support is provided with head and afterbody, support head connection carrier, and the support afterbody is provided with scale.
Described support head and afterbody interior diameter are the 5-20 millimeter, and overall diameter is the 6-25 millimeter.
Described support afterbody is connected with adjusting device, and adjusting device is located on the base, and base is provided with hold-down nut.
Described carrier is provided with thin big envelope, thin big envelope thickness 0.1-2mm.
Described adjusting device is angle and arrangement for adjusting height.
This utility model advantage is:
1, this utility model is easy, accurate, quick on prostate Transrectal Ultrasound and nuclear magnetic resonance image registration, only needs that the aspect that contains the similar number label under two kinds of imaging patterns is carried out registration and gets final product;
2, this utility model does not need to be implanted into label the patient body to patient's not damaged, avoids the damage that brings thus and uses limitation;
But 3, this utility model repeated multiple times use, each only the need changed label, and the label selection is various, can select according to condition, and the scope of application is extensive;
4, this utility model volume is small and exquisite, and is suitable with conventional Transrectal Ultrasound probe diameter, and patient tolerability is good, degree of recognition is high.
Description of drawings
Accompanying drawing 1 is a registration apparatus structural representation in a kind of prostate Transrectal Ultrasound of this utility model and the nuclear magnetic resonance image fusion chamber.
Accompanying drawing 2 is registration apparatus carrier and direct organization sketch maps in a kind of prostate Transrectal Ultrasound of this utility model and the nuclear magnetic resonance image fusion chamber.
Accompanying drawing 3 is the generalized sections along Fig. 2 A-A line.
Accompanying drawing 4 is the generalized sections along Fig. 2 B-B line.
The specific embodiment
Below in conjunction with embodiment and with reference to accompanying drawing this utility model is further described.
The Reference numeral and the ingredient that relate in the accompanying drawing are as follows:
1. carrier 11. bond site
12. ultrasonic scanning window position 121. blind cylindrical holes
13. thin big envelope 2. supports
21. head 22. afterbodys
3. adjusting device 4. bases
5. hold-down nut
Please refer to Fig. 1, Fig. 1 is a registration apparatus structural representation in a kind of prostate Transrectal Ultrasound of this utility model and the nuclear magnetic resonance image fusion chamber, registration apparatus is provided with support 2 in described prostate Transrectal Ultrasound and the nuclear magnetic resonance image fusion chamber, support 2 is a hollow cylinder, support 2 is divided into head 21 and afterbody 22, head 21 transverse section inside and outside circle diameters are consistent with afterbody 22 inner and outer diameter, described head 21 outsides are provided with carrier 1, described carrier 1 is provided with thin big envelope 13, and thin big envelope 13 can be placed on the carrier 1.Please refer to Fig. 2, Fig. 2 is registration apparatus carrier and a supporting structure sketch map in a kind of prostate Transrectal Ultrasound of this utility model and the nuclear magnetic resonance image fusion chamber, carrier 1 is divided into bond site 11 and ultrasonic scanning window position 12, bond site 11 is the bonding place of carrier 1 and support 2 heads 21, and bond site 11 is positioned at 12 two ends, ultrasonic scanning window position.Please refer to Fig. 3, Fig. 3 is the generalized section along Fig. 2 A-A line, and described carrier 1 is wrapped on the head 21 of support 2, and support 2 heads 21 interior diameters are the 5-20 millimeter, and overall diameter is the 6-25 millimeter.Described ultrasonic scanning window position 12 is provided with blind cylindrical hole 121, it is capable that described blind cylindrical hole 121 is provided with 3-9, the row distance of center circle is 2～20mm, blind cylindrical hole 121 is along the parallel distribution of carrier 1 face of cylinder long axis direction, blind cylindrical hole 121 numbers of every row differ, and its orientation is consistent with nuclear magnetic resonance, NMR and transrectal ultrasonography direction.Please refer to Fig. 4, Fig. 4 is the generalized section along Fig. 2 B-B line, and described blind cylindrical hole 121 diameters are the 1-5 millimeter, blind cylindrical hole 121 hole depth 1-5 millimeters, hole base thickness 0.1-5 millimeter, carrier 1 are wrapped on the head 21 of support 2, and described support 2 heads 21 diameters are the 5-20 millimeter.Referring again to Fig. 1, described support 2 afterbodys 22 connect adjusting device 3, and adjusting device 3 is angle and arrangement for adjusting height, and adjusting device 3 is located on the base 4, also is provided with hold-down nut 5 on the base 4.The preparation material and the method for described label are as follows:
One, label prepares material
Ferroferric oxide powder, agar, distilled water
Two, label preparation method
Take by weighing ferroso-ferric oxide 0.05g respectively and agar 100g(mass ratio is 1:2000) add distilled water and make the 500ml mixed solution, when the mixed solution heating is in a liquid state gel state, abundant mixing, the label of mix homogeneously is injected in the blind cylindrical hole 121 moulding then while hot, wait its cooled and solidified, standby.
One, label prepares material
Ferroferric oxide powder, agar, distilled water
Two, label preparation method
Take by weighing ferroso-ferric oxide 0.1g respectively and agar 100g(mass ratio is 1:1000) add distilled water and make the 500ml mixed solution, when the mixed solution heating is in a liquid state gel state, abundant mixing, the label of mix homogeneously is injected in the blind cylindrical hole 121 moulding then while hot, wait its cooled and solidified, standby.
One, label prepares material
Ferroferric oxide powder, agar, distilled water
Two, label preparation method
Take by weighing ferroso-ferric oxide 0.2g respectively and agar 100g(mass ratio is 1:500) add distilled water and make the 500ml mixed solution, when the mixed solution heating is in a liquid state gel state, abundant mixing, the label of mix homogeneously is injected in the blind cylindrical hole 121 moulding then while hot, wait its cooled and solidified, standby.
One, label prepares material
The ferroso-ferric oxide liquid formulation, agar, distilled water
Two, label preparation method
Concentration according to ferroso-ferric oxide in the ferroso-ferric oxide liquid formulation, get an amount of and agar 100g and distilled water to make 500ml ferroso-ferric oxide concentration be the mixed solution of 10～400mg/L, when the mixed solution heating is in a liquid state gel state, abundant mixing, the label of mix homogeneously is injected in the blind cylindrical hole 121 moulding then while hot, wait its cooled and solidified, standby.
Need to prove that described carrier 1 adopts silica gel material to make, carrier 1 part is for placing the carrier material of label, and this material require satisfies following feature: 1. nontoxic, have certain elasticity and plasticity; 2. it is good to lead acoustic performance, and when using ultrasonic scanning, inside is the homogenizing echoless, no acoustic attenuation and interference pseudomorphism; 3. nonmagnetic, can be in imaging under the nuclear magnetic resonance scanning, and NMR signal is even; 4. good heat resistance is stable below 100 ℃.Therefore, this utility model carrier 1 part adopts silica gel material to make, but other materials that satisfy above characteristic also can use.Described carrier 1 is wrapped on the head 21 of support 2, the afterbody 22 of support 2 is provided with scale, by the scale on the afterbody 22, can regulate carrier and insert the intrarectal degree of depth of patient, afterbody 22 is connected with adjusting device 3, and adjusting device 3 is angle and arrangement for adjusting height, and adjusting device 3 is located on the base 4, by the height of regulating hold-down nut 5 adjustable supports 2 on the base 4 and the angle that forms with horizontal plane, be convenient to use of the present utility model.
Described label is can all the material and the coagulant of video picture mix by a certain percentage under ultrasonic and nuclear magnetic resonance, NMR, embodiment selects the aqueous solution of ferroferric oxide powder and agar and the aqueous solution of ferroso-ferric oxide liquid preparation and agar for use, the label that in the proportion shown in the embodiment, prepares have this label of following characteristic: ⑴ on NMR (Nuclear Magnetic Resonance)-imaging, produce with surrounding tissue clear and definite correlated signal is arranged; ⑵ this label also produces with surrounding tissue under ultrasonic scanning clear and definite correlated echo; ⑶ two kinds of composition mix homogeneously, heating in water bath are in a liquid state during to uniform temperature, are the solid gel shape when being cooled to room temperature.Be 1:500 wherein with ferroso-ferric oxide 0.2g and agar 100g(mass ratio) adding distilled water, to make the signal that produces on the 500ml mixed solution gained label NMR (Nuclear Magnetic Resonance)-imaging the clearest and the most definite with the surrounding tissue contrast, and the echo that produces under ultrasonic scanning also contrasts the clearest and the most definite with surrounding tissue.When label is packed carrier 1 into, under being in a liquid state situation, the coagulant heating inserts in the blind cylindrical hole 121, after treating the coagulant cooled and solidified, fully smear ultrasonic examination fills up blind cylindrical hole 121 and the deaeration bubble with couplant in carrier 1 surface, put the thin big envelope 13 of making consistent size with carrier 1 material of the same race again on carrier 1 surface, thin big envelope 13 can prevent that blind cylindrical hole 121 internal labeling things from coming off, and plays the effect of fixation mark thing.Employing and carrier 1 part same material can guarantee the difference of no acoustic impedance between thin big envelope and the carrier 1, thereby do not exert an influence ultrasonographic pseudomorphism or interference.Put after the thin big envelope 13, this utility model just can use.
Using method of the present utility model is as follows: this utility model carrier 1 is put after the special thin big envelope 13, insert patient's internal rectum to certain depth, by the scale on the afterbody 22 of observing support 2, the scalable insertion depth, can adjust adjusting device 3 by the hold-down nut of adjusting on the base 45, can control angle and height that carrier inserts, nuclear magnetic resonance, NMR is carried out in the position of being convenient to reach suitable, obtains the prostatic nuclear magnetic resonance image of patient; When carrying out the aspiration biopsy of prostatic gland of Transrectal Ultrasound guiding, insert the internal rectum degree of depth at this utility model, when inserting angle and height under the consistent prerequisite with nuclear magnetic resonance check, the Transrectal Ultrasound probe is inserted from the pipeline of support 2, in the ultrasonic scanning window position 12 of carrier 1, carry out the prostate ultrasonic scanning, be same aspect and carry out two kinds of image registrations according to containing same tag thing number on nuclear magnetic resonance, NMR and the Transrectal Ultrasound image aspect, thereby realize relying on nuclear magnetic resonance, NMR to find, localized target, make the puncture of aimless system transfer the puncture of targeting to, improve carcinoma of prostate puncture result's positive rate, reduce unnecessary puncture simultaneously and count.
Registration apparatus carrier 1 adopts silica gel material to make in a kind of prostate Transrectal Ultrasound of this utility model and the nuclear magnetic resonance image fusion chamber, that the carrier 1 that silica gel material is made has is nontoxic, lead advantages such as acoustic performance is good, nonmagnetic, good heat resistance, and these advantages can guarantee the stability and the reliability of final imaging results; This utility model is simple in structure, and is easy to use, quick, only needs that the aspect that contains the similar number label under two kinds of imaging patterns is carried out registration and gets final product, and uses the special marking thing, can make imaging results more accurate; This utility model does not need to be implanted into label the patient body to patient's not damaged, avoids the damage that brings thus and uses limitation; But the use of this utility model repeated multiple times, each only the need changed label, and the label selection is various, can select according to condition, and the scope of application is extensive; This utility model volume is small and exquisite, and is suitable with conventional Transrectal Ultrasound probe diameter, and patient tolerability is good, degree of recognition is high.In addition, use this utility model to carry out the prostate biopsy of Transrectal Ultrasound guiding, can better bring into play the advantage of multi-modal diagnostic imaging method, rely on nuclear magnetic resonance, NMR (MR) to find, locate conventional Transrectal Ultrasound (TRUS) and go up negative target, by merging guided puncture with real-time Transrectal Ultrasound (TRUS), make traditional aimless system puncture transfer the puncture of targeting to, can improve carcinoma of prostate puncture result's positive rate, reduce the patient and accept the probability of prostate repeated puncture, and then alleviate patient's financial burden and save medical resource; Owing to use this device can realize the targeting puncture, can significantly reduce unnecessary puncture and count, reduce patient's the damage and the incidence rate of paracentesis infectious-related complication.
In recent years, increase raising with the residents ' health health care consciousness year by year along with China's carcinoma of prostate sickness rate, aspiration biopsy of prostatic gland under the Transrectal Ultrasound guiding is extensively carried out in China, the aspiration biopsy of prostatic gland art of Transrectal Ultrasound guiding at present and pathological diagnosis are the goldstandards of diagnosing prostate cancer before the clinic operation, it is clinical as this utility model is widely used in, can save extensive patients individual's financial burden and the spending of national medical care insurance on the one hand, associate organization makes it have certain market scale on the other hand, can obtain certain economic benefits and social benefit.
The above only is a preferred implementation of the present utility model; should be pointed out that for those skilled in the art, under the prerequisite that does not break away from this utility model principle; can also make some improvement and replenish, these improvement and replenish and also should be considered as protection domain of the present utility model.
Claims (10)
1. registration apparatus in prostate Transrectal Ultrasound and the nuclear magnetic resonance image fusion chamber, be provided with carrier, support, adjusting device and base, it is characterized in that, described carrier is located on the support, support is connected with base by adjusting device, is provided with label in the described carrier.
2. registration apparatus in prostate Transrectal Ultrasound according to claim 1 and the nuclear magnetic resonance image fusion chamber is characterized in that described carrier becomes hollow cylindrical, and carrier is provided with bond site and ultrasonic scanning window position.
3. registration apparatus in prostate Transrectal Ultrasound according to claim 2 and the nuclear magnetic resonance image fusion chamber is characterized in that described ultrasonic scanning window position is provided with blind cylindrical hole.
4. registration apparatus in prostate Transrectal Ultrasound according to claim 1 and the nuclear magnetic resonance image fusion chamber is characterized in that it is capable that described blind cylindrical hole is provided with 3-9, and the row distance of center circle is 2～20mm, and blind cylindrical hole is along the parallel distribution of carrier face of cylinder long axis direction.
5. registration apparatus in prostate Transrectal Ultrasound according to claim 4 and the nuclear magnetic resonance image fusion chamber is characterized in that described blind cylindrical hole diameter is the 1-5 millimeter, blind cylindrical hole hole depth 1-5 millimeter, hole base thickness 0.1-5 millimeter.
6. registration apparatus in prostate Transrectal Ultrasound according to claim 1 and the nuclear magnetic resonance image fusion chamber is characterized in that put up hollow cylindrical for described, support is provided with head and afterbody, support head connection carrier, and the support afterbody is provided with scale.
7. registration apparatus in prostate Transrectal Ultrasound according to claim 6 and the nuclear magnetic resonance image fusion chamber is characterized in that described support head and afterbody interior diameter are the 5-20 millimeter, and overall diameter is the 6-25 millimeter.
8. registration apparatus in prostate Transrectal Ultrasound according to claim 1 and the nuclear magnetic resonance image fusion chamber is characterized in that described support afterbody is connected with adjusting device, and adjusting device is located on the base, and base is provided with hold-down nut.
9. registration apparatus in prostate Transrectal Ultrasound according to claim 1 and the nuclear magnetic resonance image fusion chamber is characterized in that described carrier is provided with thin big envelope, thin big envelope thickness 0.1-2mm.
10. registration apparatus in prostate Transrectal Ultrasound according to claim 1 and the nuclear magnetic resonance image fusion chamber is characterized in that described adjusting device is angle and arrangement for adjusting height.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 201120149821 CN202060796U (en) | 2011-05-12 | 2011-05-12 | Prostate transrectal ultrasound and nuclear magnetic resonance (NMR) images fusion intracavity registering device |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 201120149821 CN202060796U (en) | 2011-05-12 | 2011-05-12 | Prostate transrectal ultrasound and nuclear magnetic resonance (NMR) images fusion intracavity registering device |
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| CN202060796U true CN202060796U (en) | 2011-12-07 |
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| CN 201120149821 Expired - Fee Related CN202060796U (en) | 2011-05-12 | 2011-05-12 | Prostate transrectal ultrasound and nuclear magnetic resonance (NMR) images fusion intracavity registering device |
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Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104203130A (en) * | 2012-03-29 | 2014-12-10 | 皇家飞利浦有限公司 | Quality assurance system and method for navigation-assisted procedures |
| CN107260269A (en) * | 2017-07-11 | 2017-10-20 | 哈尔滨理工大学 | A kind of ultrasound guidance robot for aspiration biopsy of prostatic gland |
| CN108577940A (en) * | 2018-02-11 | 2018-09-28 | 苏州融准医疗科技有限公司 | A kind of targeting guiding puncture system and method based on multi-modality medical image information |
| WO2020133054A1 (en) * | 2018-12-27 | 2020-07-02 | 王沁 | Puncture stent |
-
2011
- 2011-05-12 CN CN 201120149821 patent/CN202060796U/en not_active Expired - Fee Related
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104203130A (en) * | 2012-03-29 | 2014-12-10 | 皇家飞利浦有限公司 | Quality assurance system and method for navigation-assisted procedures |
| US10113889B2 (en) | 2012-03-29 | 2018-10-30 | Koninklijke Philips N.V. | Quality assurance system and method for navigation-assisted procedures |
| CN107260269A (en) * | 2017-07-11 | 2017-10-20 | 哈尔滨理工大学 | A kind of ultrasound guidance robot for aspiration biopsy of prostatic gland |
| CN107260269B (en) * | 2017-07-11 | 2024-02-02 | 哈尔滨理工大学 | Ultrasonic-guided prostate puncture biopsy robot |
| CN108577940A (en) * | 2018-02-11 | 2018-09-28 | 苏州融准医疗科技有限公司 | A kind of targeting guiding puncture system and method based on multi-modality medical image information |
| WO2020133054A1 (en) * | 2018-12-27 | 2020-07-02 | 王沁 | Puncture stent |
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Legal Events
| Date | Code | Title | Description |
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| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| C17 | Cessation of patent right | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20111207 Termination date: 20130512 |