CN202044650U - Acupoint application patch - Google Patents

Acupoint application patch Download PDF

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Publication number
CN202044650U
CN202044650U CN2011200775878U CN201120077587U CN202044650U CN 202044650 U CN202044650 U CN 202044650U CN 2011200775878 U CN2011200775878 U CN 2011200775878U CN 201120077587 U CN201120077587 U CN 201120077587U CN 202044650 U CN202044650 U CN 202044650U
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China
Prior art keywords
layer
medicine
sensitive adhesive
point application
pressure
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Expired - Lifetime
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CN2011200775878U
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Chinese (zh)
Inventor
汤春琳
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Individual
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Individual
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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

The utility model relates to an acupoint application patch, which comprises a pressure-sensitive adhesive layer and a medicine paste layer. The medicine paste layer is provided with three secondary layers which are successively overlapped and mutually adhered, and the three secondary layers respectively are a gel secondary layer, a medicine secondary layer and an adhesive sustained release secondary layer in a direction from the pressure-sensitive adhesive layer to the medicine paste layer. The acupoint application patch overcomes shortages that a medicine paste layer of an existing acupoint application patch is directly adhered at a wounded part or an acupoint part, so that medicine absorption is slow, absorption speeds are not uniform, medicine effect is short, skin breathability is poor, curative effect is not ideal, the existing application patch cannot be stored or conveyed for a long time, safety performance is poor, side effects are high and the like. In addition, the acupoint application patch take effect rapidly, and is high in curative effect, low in medicine dosage, long in medicine effect, simple, convenient and safe in use and free of side effects.

Description

A kind of point application
Technical field
This utility model relates to a kind of point application.
Background technology
About 60% of normal person's body weight is a water, 2/3 water level is wherein arranged in cell, and all the other are positioned at the extracellular, mainly are to be arranged in intercellular substance.Body fluid in the intercellular substance increases and is edema, and body fluid increases at body cavity and just forms hydrops.As the hydrothorax in thoracic cavity, the pericardial effusion of heart, the ascites in abdominal cavity, the hydrocephalus in the brain, the hydrarthrosis of articular cavity etc.Processing method to hydrops is the intracavity drain at present, and if this method cause infection easily, and this method is bigger for the misery that the patient causes mishandling, and operation is also complicated.And general point application is directly the medicine mastic to be sticked on skin, need modulate medicine before use usually, brings many inconvenience to the patient.And general point application onset is slower, and drug permeability is very poor, is unfavorable for treatment.Therefore need badly seek a kind of simple effectively, safety has no side effect, rapid-action, the point application being convenient to preserve.
The utility model content
It is directly the medicine paste layer to be affixed on affected part or acupuncture point place that technical problem to be solved in the utility model is to have overcome existing point application, thereby cause that drug absorption is slow, infiltration rate is inhomogeneous, drug effect is lasting, skin permeability is poor, curative effect is not ideal enough, applying ointment or plaster can not long preservation or defective such as transportation, poor stability, side effect be big, thereby a kind of point application with multiple structure is provided, this point application is that a kind of onset is rapid, curative effect is high, dosage is few, lasting medicine, easy to use, safely, the point application that has no side effect.
This utility model provides a kind of point application, it comprises stacked and a mutual bonding pressure-sensitive adhesive layer and a medicine paste layer, wherein this medicine paste layer has 3 stacked successively and mutual bonding sublayers, to the direction of this medicine paste layer, described 3 sublayers are respectively a gel sublayer, a medicine sublayer and adheres to the slow release sublayer at this pressure-sensitive adhesive layer.
In this utility model one preferred implementation, this point application also has a backing layer, this backing layer and this pressure-sensitive adhesive layer is stacked and bonding mutually, and this pressure-sensitive adhesive layer is between this backing layer and this medicine paste layer.This backing layer has been avoided this point application and extraneous direct the contact, has effects such as fungi-proofing, waterproof.This backing layer can be selected the backing layer of various routines in this area for use, and as plastic film layers, nonwoven layer or antiseptic gauze layer etc., preferably this backing layer comprises a layer of polyurethane (being called for short the PU layer).This PU layer can prevent drug extravasation, has ventilative, waterproof, fungi-proofing advantage simultaneously, can fix this medicine paste layer well again.More preferably, this backing layer also comprises a pet film layer (being called for short the PET plastic film layers), and this PU layer is between this pressure-sensitive adhesive layer and this PET plastic film layers.This PET plastic film layers is beneficial to and fixes this PU layer when producing this point application.The size of this PET plastic film layers is preferably more than or equal to this PU layer.After this point application is affixed on affected part and/or acupuncture point, need this PET plastic film layers is thrown off.Size for this backing layer in this utility model does not have specific (special) requirements, can select according to this area conventional method, and the size of this backing layer should be greater than the size of this pressure-sensitive adhesive layer usually.
In another preferred implementation of this utility model, this point application also has a protective layer, and this protective layer and this medicine paste layer are stacked and bonding mutually, and this medicine paste layer is between this pressure-sensitive adhesive layer and this protective layer.This is protective layer used in the pollution that prevents this medicine paste layer, can adopt the protective layer of the various routines in this area, preferably is centrifugal ply of paper.Throwing off this protective layer during use directly sticks this point application in the acupuncture point and/or the affected part gets final product.
In the better embodiment of this utility model one, this point application has this protective layer and this backing layer simultaneously.
In this utility model, this pressure-sensitive adhesive layer adopts existing various pressure sensitive adhesive to make, and generally selects medical pressure-sensitive adhesive for use.Size for this pressure-sensitive adhesive layer in this utility model does not have specific (special) requirements, can select according to this area conventional method, as long as it can be fixed on this medicine paste layer on the skin, the size of this pressure-sensitive adhesive layer should be greater than the size of this medicine paste layer usually.
In this utility model, this medicine paste layer can be cut to different shape as required, as circle, ellipse or rectangle.
In this utility model, this gel sublayer is this area various gel diaphragms commonly used, as sodium carboxymethyl cellulose gel diaphragm.This sodium carboxymethyl cellulose gel diaphragm is that the main of various routines is the gel diaphragm of raw material with the sodium carboxymethyl cellulose in the medicament field, it can be pure sodium carboxymethyl cellulose gel diaphragm, also can be the sodium carboxymethyl cellulose gel diaphragm that contains this area some additives (as the medical grade chitosan) commonly used, as sodium carboxymethyl cellulose-chitosan gel rubber diaphragm.
In this utility model, the kind of this medicine sublayer can be selected according to therapeutic purposes.When point application of the present utility model is when being used for the treatment of hydrops, this medicine sublayer preferably is the mastic diaphragm of metabolic product of staphylococcus aureus extracting solution.This mastic diaphragm is existing compositions, and it mainly is made up of metabolic product of staphylococcus aureus extracting solution, glycerol, penetrating agent and chitosan.Wherein this metabolic product of staphylococcus aureus extracting solution is the commercially available prod, also can be according to the patent of having authorized, and the patent No. is that 89105016.7 method is prepared.This penetrating agent preferably is a Borneolum Syntheticum.
In this utility model, this adhesion slow release sublayer can be selected the various adhesion slow release diaphragms of this area routine for use, preferably is the chitosan sustained-release diaphragm.This chitosan sustained-release diaphragm is that the main of various routines is the slow release diaphragm of raw material with the chitosan in the medicament field, it can be pure chitosan slow release diaphragm, also can be the chitosan sustained-release diaphragm that contains this area some additives commonly used, as the chitosan sustained-release diaphragm of mainly being made up of chitosan and glycerol, wherein glycerol can promote the penetrating of this medicine sublayer.
Used reagent and raw material is all commercially available gets in this utility model.
In this utility model, but above-mentioned optimum condition combination in any on the basis that meets this area general knowledge promptly gets each preferred embodiments of the present utility model.
Positive progressive effect of the present utility model is:
Point application of the present utility model is the method that adopts modern means of science and technology and traditional Chinese medicine meridian theory to combine, and according to subjects such as Chinese medicine, biotechnology, modern physics, materialogy progress, development and design forms.It plays a role by point application transdermal administration and meridian point effect.This point application can make skin be easy to allow drug molecule pass through, and through the cave conduction, is penetrated into blood thereby enter skin corium, directly to the affected part administration, reduces the side reaction of medicine to stomach, liver, kidney, reaches therapeutic purposes efficiently.The medicine sublayer slowly discharges under the control that adheres to the slow release sublayer simultaneously, thereby has reduced dosage, but drug action is lasting.During use, throw off protective layer, directly stick in the corresponding treatment acupuncture point, easy to use, safe.
Description of drawings
Fig. 1 is the front view of the point application of embodiment 1.
Fig. 2 is the structural representation of point application Chinese medicine paste layer 3 shown in Figure 1.
Fig. 3 is the partial enlarged drawing of a part in the point application shown in Figure 1.
Fig. 4 is the structural representation of the point application of embodiment 1.
Reference numerals list:
The 1-backing layer; The 2-pressure-sensitive adhesive layer; 3-medicine paste layer; The 4-protective layer;
5-gel sublayer; 6-medicine sublayer; 7-adheres to the slow release sublayer; The 8-PU layer;
The 9-PET plastic film layers.
The specific embodiment
Below by the mode of embodiment, accompanying drawings further specifies this utility model content, characteristics and effect, but therefore this utility model is not limited among the described scope of embodiments.
The extract of metabolic product of staphylococcus aureus described in the embodiment is purchased in credit river, Zhejiang pharmaceutcal corporation, Ltd, and commodity are called En Gefei.
The chitosan that uses among the embodiment is a medical chitosan of purchasing the emerging one-tenth biological factory in Nantong, wherein deacetylation>90%.
Embodiment 1
Fig. 1 shows a point application, and it comprises stacked successively and a mutual bonding protective layer 4, a medicine paste layer 3, a pressure-sensitive adhesive layer 2 and a backing layer 1.Wherein, as shown in Figure 2, this medicine paste layer 3 to the direction of this pressure-sensitive adhesive layer 2, comprises stacked successively and bonding mutually an adhesion slow release sublayer 7, a medicine sublayer 6 and a gel sublayer 5 at this protective layer.As shown in Figure 3, this backing layer 1 comprises a stacked and bonding PU layer 8 and a PET plastic film layers 9 mutually at this protective layer 4 to the direction of this pressure-sensitive adhesive layer 2.Wherein, the area of this PET plastic film layers 9 is greater than this PU layer 8.The area of this backing layer 4 is greater than the area of this pressure-sensitive adhesive layer 2, and the area of this pressure-sensitive adhesive layer is greater than the area of this medicine paste layer 3.
This gel sublayer 5 is sodium carboxymethyl cellulose-chitosan gel rubber diaphragm, its preparation method is: (1) is that the acetic acid of 2% (V/V) mixes with chitosan and concentration, at room temperature stir, leave standstill and remove insoluble matter, be mixed with chitosan mass concentration and be 2% chitosan rubber cement; (2) in described chitosan rubber cement, add sodium carboxymethyl cellulose, leave standstill, de-bubble, the coating film forming sheet, the mass concentration of sodium carboxymethyl cellulose is 3% in the diaphragm.
This medicine sublayer 6 is the medicine layer of metabolic product of staphylococcus aureus extract, its preparation method is: (1) is that the acetic acid of 2% (V/V) mixes with chitosan and concentration, at room temperature stir, leave standstill and remove insoluble matter, be mixed with chitosan mass concentration and be 2% chitosan rubber cement; (2) with metabolic product of staphylococcus aureus extract 40kg and glycerol 7kg, Borneolum Syntheticum 8kg and chitosan rubber cement 45kg mixing, leave standstill de-bubble, coating film forming sheet on coating machine.
This adheres to slow release sublayer 7 be that its preparation method is by chitosan-based slow release diaphragm: (1) is that the acetic acid of 2% (V/V) mixes with chitosan and concentration, and at room temperature stirring is left standstill and removed insoluble matter, is mixed with chitosan mass concentration and is 2% chitosan rubber cement; (2) add the glycerol that accounts for chitosan rubber cement quality 5%, stir, leave standstill, de-bubble, diaphragm is made in coating.
This protective layer 4 is centrifugal ply of paper.
The preparation method of this medicine paste layer 3 is: this gel sublayer 5, this medicine sublayer 6 and this adhesion slow release sublayer 7 is bonding successively, and the circle that cuts into diameter 2-4cm gets final product.
The preparation method of this point application is: this PU layer 8 and this PET plastic film layers 9 are bonded together, this pressure-sensitive adhesive layer 2 is sticked on this PU layer 8, this medicine paste layer 3 is bonded on this pressure-sensitive adhesive layer 2, at last protective layer 4 is pasted.
During use, throw off protective layer 4, directly stick on the acupuncture point, tear this PET plastic film layers 9 of this backing layer 1 then off, get final product.
Effect embodiment 1
The point application of embodiment 1 is affixed on hydrops generation chest position, joins caves such as fei shu, Pishu, shen shu, pang kuang shu, apply ointment or plaster and changed once in 24 hours, 7-15 days courses of treatment.This point application has inhibiting bacteria and diminishing inflammation, improves immunity, reduces the effect of hydrothorax, and patient's quality of life is improved.

Claims (7)

1. point application, it is characterized in that: it comprises stacked and a mutual bonding pressure-sensitive adhesive layer and a medicine paste layer, wherein this medicine paste layer has 3 stacked successively and mutual bonding sublayers, to the direction of this medicine paste layer, described 3 sublayers are respectively a gel sublayer, a medicine sublayer and adheres to the slow release sublayer at this pressure-sensitive adhesive layer.
2. point application as claimed in claim 1 is characterized in that: this point application also has a backing layer, this backing layer and this pressure-sensitive adhesive layer is stacked and bonding mutually, and this pressure-sensitive adhesive layer is between this backing layer and this medicine paste layer.
3. point application as claimed in claim 1 or 2 is characterized in that: this point application also has a protective layer, and this protective layer and this medicine paste layer are stacked and bonding mutually, and this medicine paste layer is between this pressure-sensitive adhesive layer and this protective layer.
4. point application as claimed in claim 1 is characterized in that: this medicine paste layer is circle, ellipse or rectangle.
5. point application as claimed in claim 2 is characterized in that: this backing layer comprises a layer of polyurethane.
6. point application as claimed in claim 5 is characterized in that: this backing layer also comprises a pet film layer, and this layer of polyurethane is between this pressure-sensitive adhesive layer and this pet film layer.
7. point application as claimed in claim 3 is characterized in that: this protective layer is centrifugal ply of paper.
CN2011200775878U 2011-03-22 2011-03-22 Acupoint application patch Expired - Lifetime CN202044650U (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN2011200775878U CN202044650U (en) 2011-03-22 2011-03-22 Acupoint application patch

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN2011200775878U CN202044650U (en) 2011-03-22 2011-03-22 Acupoint application patch

Publications (1)

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CN202044650U true CN202044650U (en) 2011-11-23

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CN2011200775878U Expired - Lifetime CN202044650U (en) 2011-03-22 2011-03-22 Acupoint application patch

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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107970352A (en) * 2017-12-07 2018-05-01 泰州培生源医疗器械有限公司 Shoulder neck waist-leg acupuncture point Pressure stimulation patch
CN109432066A (en) * 2018-12-27 2019-03-08 深圳津梁生活科技有限公司 A kind of external drug application
CN112691187A (en) * 2020-12-30 2021-04-23 深圳新发源植物科技发展有限公司 Sustained-release film for preventing forehead alopecia and preparation method thereof

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107970352A (en) * 2017-12-07 2018-05-01 泰州培生源医疗器械有限公司 Shoulder neck waist-leg acupuncture point Pressure stimulation patch
CN109432066A (en) * 2018-12-27 2019-03-08 深圳津梁生活科技有限公司 A kind of external drug application
CN112691187A (en) * 2020-12-30 2021-04-23 深圳新发源植物科技发展有限公司 Sustained-release film for preventing forehead alopecia and preparation method thereof

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Date Code Title Description
C14 Grant of patent or utility model
GR01 Patent grant
EE01 Entry into force of recordation of patent licensing contract

Assignee: Shaanxi embellish biological Co., Ltd.

Assignor: Tang Chunlin

Contract record no.: 2015990000384

Denomination of utility model: Emplastrum for applied on acupuncture points and preparation method thereof

Granted publication date: 20111123

License type: Common License

Record date: 20150528

LICC Enforcement, change and cancellation of record of contracts on the licence for exploitation of a patent or utility model
CX01 Expiry of patent term

Granted publication date: 20111123

CX01 Expiry of patent term