CN202018537U - Optical-tweezers device based on wave-front phase modulation - Google Patents

Optical-tweezers device based on wave-front phase modulation Download PDF

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CN202018537U
CN202018537U CN2011201198647U CN201120119864U CN202018537U CN 202018537 U CN202018537 U CN 202018537U CN 2011201198647 U CN2011201198647 U CN 2011201198647U CN 201120119864 U CN201120119864 U CN 201120119864U CN 202018537 U CN202018537 U CN 202018537U
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李劲松
郭玲
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China Jiliang University
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Abstract

本实用新型涉及一种基于波前相位调制的光镊装置,属于应用光学技术领域,主要应用于光学微操纵及光与物质相互作用等领域。其装置由光源发射部件、光束直径调节器、相位波前调节器、光学聚焦部件组成;光源发射部件出射光束方向上依次置有光束直径调节器、相位波前调节器和光学聚焦部件,所述的相位波前调节器是带有相位拓朴数的环形相位波前调节器。本实用新型具有实现调控光镊、调控便捷、光能量利用率高、系统简洁等优点。

Figure 201120119864

The utility model relates to an optical tweezers device based on wavefront phase modulation, belongs to the field of applied optics technology, and is mainly used in the fields of optical micro-manipulation, interaction between light and matter, and the like. The device is composed of a light source emitting part, a beam diameter adjuster, a phase wavefront adjuster, and an optical focusing part; the light source emitting part is sequentially provided with a beam diameter adjuster, a phase wavefront adjuster and an optical focusing part in the direction of the outgoing beam. The phase wavefront modifier of is a ring phase wavefront modifier with a phase topology. The utility model has the advantages of realizing regulation and control of optical tweezers, convenient regulation and control, high utilization rate of light energy, simple system and the like.

Figure 201120119864

Description

一种基于波前相位调制的光镊装置An optical tweezers device based on wavefront phase modulation

技术领域:Technical field:

本实用新型属于应用光学技术领域,与聚焦光学系统焦点区域光强调节系统有关,特别是一种基于波前相位调制的光镊装置。主要应用于光学微操纵及光与物质相互作用等领域。The utility model belongs to the technical field of applied optics, relates to a light intensity adjustment system in a focus area of a focusing optical system, in particular to an optical tweezers device based on wavefront phase modulation. It is mainly used in the fields of optical micro-manipulation and interaction between light and matter.

背景技术:Background technique:

早在1970年贝尔实验室的A·Ashkin就利用多光束激光的三维势阱成功镊起并移动水溶液中的小玻璃珠。之后,这一激光镊起微粒的技术得到不断改进,所能捕获的粒子越来越小,1985年A·Ashkin开始采用单光束镊起细菌及病毒等微小生物体,1987年利用1064纳米的激光成功镊起病毒。在其后的20年间这一技术得到广泛的应用和发展,派生出透镜光纤光镊、微透镜阵列光镊、全息阵列光镊等可以应用于某些特殊领域的远场光镊技术,并成为生物医学、化学、物理学、光谱学、微细加工等众多学科领域中的研究工具。在纳米技术和生命科学迅速发展的21世纪,做为这两个领域得力工具的光镊技术的研究和应用得到了迅速的发展,特别是在生命科学领域,光镊已成为研究单个细胞和生物大分子行为不可或缺的有效工具。近些年来,两束光的相干模式又被利用来构成可调控的光镊子,并且可以通过改变两束光的频率差或光程差来连续地旋转被捕获的多个颗粒(K.Dholakia et al,“Simultaneous micromanipulation in multipleplanes using a self reconstructing light beam,”Nature 2002,419,145,and“Creation and manipulation of three-dimensionaloptically trapped structures,”Science 2002,296,p1101-1103),尽管此种构成光镊子的在先技术具有一定的优点,但是仍然存在以下不足:As early as 1970, A. Ashkin of Bell Laboratories successfully tweezed and moved small glass beads in aqueous solution by using the three-dimensional potential well of multi-beam laser. After that, the technology of laser tweezing particles has been continuously improved, and the particles that can be captured are getting smaller and smaller. In 1985, A. Ashkin began to use single beam tweezers to lift tiny organisms such as bacteria and viruses. In 1987, he used a laser of 1064 nanometers. The virus was successfully tweezed. In the following 20 years, this technology has been widely used and developed, and derived far-field optical tweezers such as lens fiber optical tweezers, microlens array optical tweezers, and holographic array optical tweezers, which can be applied to some special fields, and have become Research tools in many disciplines such as biomedicine, chemistry, physics, spectroscopy, microfabrication, etc. In the 21st century with the rapid development of nanotechnology and life science, the research and application of optical tweezers technology, which is a powerful tool in these two fields, has been developed rapidly. Especially in the field of life science, optical tweezers has become the Indispensable and efficient tool for macromolecular behavior. In recent years, the coherent mode of two beams of light has been used to form adjustable optical tweezers, and the trapped particles can be continuously rotated by changing the frequency difference or optical path difference of the two beams (K.Dholakia et al. al, "Simultaneous micromanipulation in multiple planes using a self reconstructing light beam," Nature 2002, 419, 145, and "Creation and manipulation of three-dimensional optically trapped structures," Science 2002, 296, p1101-1103), although this The prior art of tweezers has certain advantages, but there are still following deficiencies:

1)可调控光镊子需要两束光源进行相干,形成干涉模式来构成光镊子,装置结构复杂,部件多。1) Adjustable optical tweezers require two beams of light sources to be coherent to form an interference pattern to form optical tweezers. The structure of the device is complex and there are many components.

2)光镊子装置中被捕获的粒子通过开关光源或大幅度调整光强来实现颗粒的捕获和释放,控制方式灵活性差,甚至影响装置使用寿命。2) The particles trapped in the optical tweezers device are captured and released by switching the light source or adjusting the light intensity greatly, which has poor control flexibility and even affects the service life of the device.

发明内容Contents of the invention

本实用新型为了解决上述现有技术的问题,提供了一种部件少、光能量利用率高、系统简洁的实现光镊的装置。In order to solve the above-mentioned problems in the prior art, the utility model provides a device for realizing optical tweezers with few parts, high utilization rate of light energy and simple system.

本实用新型解决上述技术问题所采用的技术方案为一种实现光镊的装置,由光源发射部件、光束直径调节器、相位波前调节器、光学聚焦部件组成;光源发射部件出射光束方向上依次置有光束直径调节器、相位波前调节器和光学聚焦部件,其特点是:所述的相位波前调节器是带有相位拓朴数的环形相位波前调节器。The technical scheme adopted by the utility model to solve the above-mentioned technical problems is a device for realizing optical tweezers, which is composed of a light source emitting part, a beam diameter adjuster, a phase wave front adjuster, and an optical focusing part; It is equipped with a beam diameter adjuster, a phase wavefront adjuster and an optical focusing component, and is characterized in that the phase wavefront adjuster is a ring phase wavefront adjuster with a phase topology.

本实用新型所述的带有相位拓朴数的环形相位波前调节器是区域半径大小可变的部件。调节相位呈螺旋状变化,波前相位调节器的相对半径和拓扑数可调。The annular phase wave front adjuster with phase topology number described in the utility model is a component with variable area radius. The adjustment phase changes in a spiral shape, and the relative radius and topological number of the wavefront phase adjuster are adjustable.

本实用新型所述的带有相位拓朴数的环形相位波前调节器为可编程相位型空间光调制器、可编程液晶光学相位控制器件、光机电集成相位控制器件。The annular phase wave front adjuster with phase topology number described in the utility model is a programmable phase spatial light modulator, a programmable liquid crystal optical phase control device, and an optical-mechanical-electrical integrated phase control device.

本实用新型所述的光束直径调节器为光束扩束倍率可调的光束扩束光学部件。The beam diameter adjuster described in the utility model is an optical component for beam expansion with adjustable beam expansion ratio.

作为优选,所述的光束扩束倍率可调的光束扩束光学部件为伽利略型扩束镜或开普敦型扩束镜。Preferably, the beam expander optical component with adjustable beam expander magnification is a Galilean beam expander or a Capeton beam expander.

作为优选,所述的光源发射部件为氦氖激光器。Preferably, the light source emitting part is a helium-neon laser.

作为优选,所述的光学聚焦部件为尼康平场复消色差物镜。Preferably, the optical focusing component is a Nikon plan apochromat objective lens.

本实用新型相对现有技术具有的优点和有益效果为:Compared with the prior art, the utility model has advantages and beneficial effects as follows:

1)只用一束光形成可以操控的光镊子,装置结构简单,部件少。1) Only one beam of light is used to form controllable optical tweezers, the device has a simple structure and few components.

2)光镊子装置中被捕获的粒子通过调节相位来实现颗粒的捕获和释放,控制方式灵活性好,装置使用寿命长。2) The particles trapped in the optical tweezers device can be captured and released by adjusting the phase, the control method is flexible, and the device has a long service life.

3)实现装置结构简单,操作方便,容易实现自动化。3) The device has a simple structure, is convenient to operate, and is easy to realize automation.

4)实现在颗粒所在位置处,可以方便地调节,不断地形成新的光镊子捕获颗粒,然后搬运到目的地。4) It can be conveniently adjusted at the position of the particle, and new optical tweezers are continuously formed to capture the particle, and then transported to the destination.

附图说明Description of drawings

图1为本实用新型实施例的系统结构示意图;Fig. 1 is the system structure schematic diagram of the utility model embodiment;

图2为本实用新型实施例波前调节器示意图;Fig. 2 is the schematic diagram of the wavefront adjuster of the embodiment of the utility model;

图3为本实用新型实施例的光镊分布图;Fig. 3 is the optical tweezers distribution diagram of the utility model embodiment;

图4为本实用新型实施例的光镊分布图Fig. 4 is the optical tweezers distribution diagram of the utility model embodiment

图5为本实用新型实施例的光镊分布图Fig. 5 is the optical tweezers distribution diagram of the utility model embodiment

图6为本实用新型实施例的光镊分布图。Fig. 6 is a distribution diagram of the optical tweezers of the embodiment of the present invention.

具体实施方式Detailed ways

以下结合附图对本实用新型作进一步详细描述,以下实施例是本实用新型比较好的应用形式,但以下实施例不应看作是对本实用新型的限制。The utility model is further described in detail below in conjunction with the accompanying drawings. The following examples are better application forms of the utility model, but the following examples should not be regarded as a limitation of the utility model.

实施例Example

本实施例的以下部分描述了一种实现光镊的装置:The following sections of this example describe a setup for implementing optical tweezers:

如图1所示,本实用新型的实现光镊的装置包括氦氖激光器1、开普敦型扩束镜2、可编程相位型空间光调制器3和尼康平场复消色差物镜4组成,开普敦型扩束镜2、可编程相位型空间光调制器3和尼康平场复消色差物镜4依次设置在氦氖激光器1的出光路径上。As shown in Figure 1, the device for realizing optical tweezers of the present utility model comprises a helium-neon laser 1, a Cape Town type beam expander 2, a programmable phase-type spatial light modulator 3 and a Nikon plan apochromatic objective lens 4. The Cape Town type beam expander 2, the programmable phase spatial light modulator 3 and the Nikon plan apochromat objective lens 4 are sequentially arranged on the light output path of the He-Ne laser 1.

工作时,氦氖激光器1出射相干光束经过开普敦型扩束镜2,开普敦型扩束镜2对光束进行扩束,扩束后的激光束经过可编程相位型空间光调制器3,如图2所示,可编程相位型空间光调制器3对入射的激光束的波前相位分布进行了螺旋状相位变化调节,使相位分布呈现螺旋状相位变化,具有螺旋状相位波前的激光束经过尼康平场复消色差物镜4聚焦后,如图3--6所示,在焦点区域形成了的光镊。When working, the coherent beam emitted by the He-Ne laser 1 passes through the Cape-type beam expander 2, and the Cape-type beam expander 2 expands the beam, and the expanded laser beam passes through the programmable phase-type spatial light modulator 3 , as shown in FIG. 2 , the programmable phase spatial light modulator 3 adjusts the wavefront phase distribution of the incident laser beam in a helical phase change, so that the phase distribution presents a helical phase change, and has a helical phase wavefront After the laser beam is focused by the Nikon plan apochromat objective lens 4, as shown in Figure 3-6, optical tweezers are formed in the focal area.

相位波前调节器是带有相位拓朴数的环形相位波前调节器,及光束经过相位波前调节器进行波前相位调节后,光束的波前具有拓扑分布,例如,选择相位拓扑分布为

Figure BSA00000478855800041
其中i为单位虚数,
Figure BSA00000478855800042
为光束横截面上的方向角坐标,m为相位拓朴数。环形相位波前指的是光束波前相位在具有相位拓扑分布同时还具有在横向呈现环带状分布。在使用带有相位拓朴数的环形相位波前调节器这一技术手段时,可以通过可编程相位型空间光调制器、可编程液晶光学相位控制器件和光机电集成相位控制器件来实现,例如,选择可编程相位型空间光调制器,可编程相位型空间光调制器是现有产品化的器件,国际著名品牌供应商包括HOLOEYE、BNS、HAMAMATSU等公司,分为反射式和透射式两种,均可以通过图形用户界面软件任意调节反射或透过光束的波前相位,本实用新型中将带有相位拓朴数的环形相位波前分布函数导入可编程相位型空间光调制器的图形用户界面软件,即可实现光束的带有相位拓朴数的环形相位波前分布,本实施例中采用的具体带有相位拓朴数的环形相位波前调节器为HOLOEYE公司型号为LC-R 2500空间光调制器。The phase wavefront adjuster is a ring-shaped phase wavefront adjuster with a phase topology number, and after the beam is adjusted by the phase wavefront adjuster, the wavefront of the beam has a topological distribution. For example, the phase topological distribution is selected as
Figure BSA00000478855800041
where i is a unit imaginary number,
Figure BSA00000478855800042
is the direction angle coordinate on the cross-section of the beam, and m is the phase topology number. The annular phase wavefront means that the wavefront phase of the beam has a phase topological distribution and also has a ring-like distribution in the transverse direction. When using the technical means of ring phase wavefront adjuster with phase topology number, it can be realized by programmable phase spatial light modulator, programmable liquid crystal optical phase control device and optomechanical integrated phase control device, for example, Select the programmable phase spatial light modulator. The programmable phase spatial light modulator is an existing productized device. International famous brand suppliers include HOLOEYE, BNS, HAMAMATSU and other companies, which are divided into two types: reflective and transmissive. The wavefront phase of the reflected or transmitted light beam can be adjusted arbitrarily through the graphical user interface software. In the utility model, the annular phase wavefront distribution function with the phase topology number is introduced into the graphical user interface of the programmable phase spatial light modulator Software can realize the annular phase wavefront distribution with the phase topology number of the light beam. The specific annular phase wavefront regulator with the phase topology number used in this embodiment is the LC-R 2500 space of the HOLOEYE company model light modulator.

本实用新型的关键是,用带有相位拓朴数的环形相位波前调节器调节激光束的波前相位的手段,实现形成光镊的目的。凡是采用本实用新型的相似结构、方法及其相似变化,均应列入本实用新型的保护范围。The key of the utility model is to realize the purpose of forming optical tweezers by means of adjusting the wavefront phase of the laser beam by means of an annular phase wavefront adjuster with a phase topology number. All similar structures, methods and similar changes of the utility model should be included in the protection scope of the utility model.

Claims (7)

1.一种基于波前相位调制的光镊装置,其装置由光源发射部件、光束直径调节器、相位波前调节器、光学聚焦部件组成;光源发射部件出射光束方向上依次置有光束直径调节器、相位波前调节器和光学聚焦部件,其特征在于:所述的相位波前调节器是带有相位拓朴数的环形相位波前调节器。1. An optical tweezers device based on wavefront phase modulation, which is composed of a light source emitting part, a beam diameter adjuster, a phase wavefront adjuster, and an optical focusing part; the light source emitting part is sequentially equipped with beam diameter adjustments in the direction of the outgoing beam A device, a phase wavefront adjuster and an optical focusing component are characterized in that: the phase wavefront adjuster is an annular phase wavefront adjuster with a phase topology. 2.根据权利要求1所述的基于波前相位调制的光镊装置,其特征在于:所述的带有相位拓朴数的环形相位波前调节器是区域半径大小可变的部件。2. The optical tweezers device based on wavefront phase modulation according to claim 1, characterized in that: said annular phase wavefront adjuster with phase topology is a component with a variable area radius. 3.根据权利要求1所述的基于波前相位调制的光镊装置,其特征在于:所述的带有相位拓朴数的环形相位波前调节器为可编程相位型空间光调制器、可编程液晶光学相位控制器件、光机电集成相位控制器件。3. The optical tweezers device based on wavefront phase modulation according to claim 1, characterized in that: the described annular phase wavefront adjuster with phase topology number is a programmable phase type spatial light modulator, Program liquid crystal optical phase control devices, optomechanical integrated phase control devices. 4.根据权利要求1所述的基于波前相位调制的光镊装置,其特征在于:所述的光束直径调节器为光束扩束倍率可调的光束扩束光学部件。4. The optical tweezers device based on wavefront phase modulation according to claim 1, characterized in that: said beam diameter adjuster is a beam expansion optical component with adjustable beam expansion magnification. 5.根据权利要求5所述的基于波前相位调制的光镊装置,其特征在于:所述的光束扩束倍率可调的光束扩束光学部件为伽利略型扩束镜或开普敦型扩束镜。5. The optical tweezers device based on wavefront phase modulation according to claim 5, characterized in that: the beam expansion optical component with adjustable beam expansion magnification is a Galilean beam expander or a Capeton type beam expander. beam mirror. 6.根据权利要求1所述的基于波前相位调制的光镊装置,其特征在于:所述的光源发射部件为氦氖激光器。6. The optical tweezers device based on wavefront phase modulation according to claim 1, characterized in that: said light source emitting part is a He-Ne laser. 7.根据权利要求1所述的基于波前相位调制的光镊装置,其特征在于:所述的光学聚焦部件为尼康平场复消色差物镜。7. The optical tweezers device based on wavefront phase modulation according to claim 1, characterized in that: said optical focusing component is a Nikon plan apochromat objective lens.
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CN102566077A (en) * 2012-02-10 2012-07-11 上海理工大学 Multifocal imaging device and method
CN102706444A (en) * 2012-06-25 2012-10-03 杭州电子科技大学 Method for measuring topological charges of optical vortex
CN106908945A (en) * 2016-05-05 2017-06-30 中国计量大学 A kind of dual-beam optical tweezer based on optical modulator
CN106908946A (en) * 2016-05-05 2017-06-30 中国计量大学 A kind of dual-beam optical optical tweezers system of simplification
CN111213220A (en) * 2017-10-17 2020-05-29 安特卫普大学 Spatial Phase Manipulation of Charged Particle Beams

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102566077A (en) * 2012-02-10 2012-07-11 上海理工大学 Multifocal imaging device and method
CN102706444A (en) * 2012-06-25 2012-10-03 杭州电子科技大学 Method for measuring topological charges of optical vortex
CN102706444B (en) * 2012-06-25 2014-08-13 杭州电子科技大学 Method for measuring topological charges of optical vortex
CN106908945A (en) * 2016-05-05 2017-06-30 中国计量大学 A kind of dual-beam optical tweezer based on optical modulator
CN106908946A (en) * 2016-05-05 2017-06-30 中国计量大学 A kind of dual-beam optical optical tweezers system of simplification
CN106908946B (en) * 2016-05-05 2019-03-22 中国计量大学 A kind of dual-beam optical optical tweezers system of simplification
CN106908945B (en) * 2016-05-05 2019-10-08 中国计量大学 A kind of dual-beam optical tweezer based on optical modulator
CN111213220A (en) * 2017-10-17 2020-05-29 安特卫普大学 Spatial Phase Manipulation of Charged Particle Beams

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