CN201988227U - Chromatographic column with pressurizing piston - Google Patents
Chromatographic column with pressurizing piston Download PDFInfo
- Publication number
- CN201988227U CN201988227U CN2011200837338U CN201120083733U CN201988227U CN 201988227 U CN201988227 U CN 201988227U CN 2011200837338 U CN2011200837338 U CN 2011200837338U CN 201120083733 U CN201120083733 U CN 201120083733U CN 201988227 U CN201988227 U CN 201988227U
- Authority
- CN
- China
- Prior art keywords
- pressurizing piston
- end cover
- feed pipe
- cylindrical shell
- chromatographic column
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Abstract
The utility model discloses a chromatographic column with a pressurizing piston, which comprises a cylinder body, an upper end cover fixedly connected to the upper end of the cylinder body through a flange, a round base arranged at the lower end of the cylinder body, the pressurizing piston positioned inside the cylinder body and hermetically matched with the inner wall of the cylinder body, and a feeding pipe connected to the upper end of the pressurizing piston, wherein a discharge hole is formed on the round base, the pressurizing piston corresponds to the feeding pipe and is provided with a feed opening, the upper part of the feeding pipe penetrates through the upper end cover and protrudes outwards, the feeding pipe is a round pipe with external threads, the protruding part of the feeding pipe is sleeved with a drive nut used for driving the feeding pipe to move up and down, and a reducing motor is arranged on the upper end cover and connected with the drive nut through a transmission mechanism. The chromatographic column serves as equipment for mass production. The pressurization of the pressurizing piston in the utility model can be accomplished through the driving of the reducing motor, manual manipulation is not required during the entire process, and the production efficiency is improved greatly.
Description
Technical field
The utility model relates to the separator of a kind of biology, chemical field, is specifically related to a kind of chromatographic column with pressurizing piston.
Background technology
Chromatographic isolation is the present most effective a kind of method of purification means in pharmaceutical industry, biological chemical field, is one of the separation of natural products and important means of other high purity substance preparation, uses more and more widely.Chromatographic column is the key equipment of chromatographic isolation, and it carries out separating substances by the gel chromatography technology.Chromatographic column is made of transparent cylindrical shell and the gel column that is arranged in the transparent cylindrical shell usually, the chromatography media (as sephadex, Ago-Gel, polyacrylamide gel etc.) that constitutes gel column is for having the network structure of a certain size hole, because molecular size, the shape difference of separated material are diffused into the speed difference in the gel pore, therefore separate by the speed difference of gel column.
China's utility model patent (patent No. is 201020122183.1) discloses " a kind of novel chromatographic column ", comprises cylinder, cylinder upper port edge arranged outside upper end cover, cylinder lower port edge arranged outside cup dolly; Be provided with the hollow adjustable column in the cylinder upper port, the hollow adjustable column is connected with upper end cover by upper end cover; Hollow adjustable column lower end is provided with rubber stopper; Be provided with filter and sealing gasket in the cylinder lower port; The cylinder lower end is provided with bottom end cover, and bottom end cover is threaded with filter by adjustable pipe with filter; The filter bottom is provided with drain pipe.
Yet, by regulating the motion that the hollow adjustable column drives rubber stopper, exert pressure thereby give in the cylinder, the adjusting of centering air-conditioning segmented column is finished by manual fully, when needs are produced in enormous quantities, when adopting bigger equipment, manual adjustment hollow adjustable column can consume a large amount of muscle power of operator, also can badly influence operating efficiency, even work can't be carried out.Above-mentioned chromatographic column is sealed and matched by rubber stopper and cylinder, when needs are produced in enormous quantities, when adopting bigger equipment, brings inconvenience obviously can for the dismounting of equipment, cleaning.
Above-mentioned chromatographic column only is applicable to that it is comparatively inapplicable just to seem, needs a kind of chromatographic column that can be applicable to production in enormous quantities in the prior art badly in experiment or the small lot batch manufacture when producing in enormous quantities.
The utility model content
The purpose of this utility model is to overcome deficiency of the prior art, and a kind of chromatographic column with pressurizing piston that can produce in enormous quantities is provided, and this chromatographic column has higher operating efficiency.
The purpose of this utility model realizes by following scheme: a kind of chromatographic column with pressurizing piston, comprise cylindrical shell, be fixedly connected on the upper end cover of cylindrical shell upper end by flange, be arranged at the cup dolly of cylindrical shell lower end, be positioned at the pressurizing piston that cylindrical shell and cylinder inboard wall are sealed and matched, be connected in the feed pipe of pressurizing piston upper end, described cup dolly is provided with discharge opening, described pressurizing piston is provided with charging aperture corresponding to described feed pipe, it is protruding that described upper end cover is passed on the top of described feed pipe, described feed pipe is for having externally threaded round tube, the extension of described feed pipe is arranged with and is used to drive the drive nut that feed pipe moves up and down, described upper end cover is provided with reducing motor, and described reducing motor is connected with described drive nut by transmission mechanism.
The ammeter that also comprises column, fixedly connected with described pressurizing piston in the lower end of described ammeter, and it is protruding that described upper end cover is passed on the top of described ammeter, and described ammeter is provided with indicating graduation.
Described pressurizing piston comprises the gas-flow closure circle of piston plate and annular, the circumferential surface of described piston plate has mounting groove, described gas-flow closure circle is arranged in the described mounting groove, described gas-flow closure circle has pore, described pore is connected with pressure line, and described pressure line passes described upper end cover and is connected with air feed equipment.
The lower end of described pressurizing piston is fixedly connected with the circular distribution plate that is formed by multilayer stainless (steel) wire sintering.
Advantage of the present utility model is: the equipment of the utility model for producing in enormous quantities.Because pressurizing piston is connected with reducing motor by feed pipe, drive pressurizing piston by reducing motor and move up and down, thereby pressurize, whole process does not need manual operations, has improved production efficiency greatly.Pressurizing piston is made of piston plate and gas-flow closure circle, is sealed and matched to making between pressurizing piston and the cylindrical shell after the inflation of gas-flow closure circle during work; Need to clean, during dismounting, venting get final product to the gas-flow closure circle, make clean, dismantle very convenient.
Description of drawings
Fig. 1 is the perspective view with chromatographic column of pressurizing piston of the present utility model;
Fig. 2 is upper end cover and the pressurizing piston structural representation partly with chromatographic column of pressurizing piston of the present utility model.
In the drawings: 1. cylindrical shell; 2. upper end cover; 3. cup dolly; 4. feed pipe; 5. discharge opening; 6. reducing motor; 7. ammeter; 8. piston plate; 9. gas-flow closure circle; 10. pressure line; 11. circular distribution plate; Air feed equipment 12; Flange 13.
The specific embodiment
Below in conjunction with accompanying drawing the utility model is described further.
As Fig. 1, shown in Figure 2, a kind of chromatographic column with pressurizing piston, comprise cylindrical shell 1, be fixedly connected on the upper end cover 2 of cylindrical shell 1 upper end by flange 13, be arranged at the cup dolly 3 of cylindrical shell 1 lower end, be positioned at the pressurizing piston that cylindrical shell 1 cooperates with cylindrical shell 1 inner wall sealing, be connected in the feed pipe 4 of pressurizing piston upper end, cup dolly 3 is provided with discharge opening 5, pressurizing piston is provided with charging aperture corresponding to feed pipe 4, it is protruding that upper end cover 2 is passed on the top of feed pipe 4, feed pipe 4 is for having externally threaded round tube, the extension of feed pipe 4 is arranged with and is used to drive the drive nut that feed pipe 4 moves up and down, upper end cover 2 is provided with reducing motor 6, and reducing motor 6 is connected with drive nut by transmission mechanism.
When needs pressurize in cylindrical shell 1, open reducing motor 6, reducing motor 6 drives feed pipe 4 and moves downward, thereby make pressurizing piston move downward, pressurize by transmission mechanism, drive nut.
In the utility model, also comprise the ammeter 7 of column, fixedly connected with pressurizing piston in the lower end of ammeter 7, and it is protruding that upper end cover 2 is passed on the top of ammeter 7, and ammeter 7 is provided with indicating graduation.Indicating graduation by height of observation indicator 7 can in time be understood the pressurization situation of pressurizing piston.
As shown in Figure 1, pressurizing piston comprises the gas-flow closure circle 9 of piston plate 8 and annular, the circumferential surface of piston plate 8 has mounting groove, gas-flow closure circle 9 is arranged in the mounting groove, gas-flow closure circle 9 has pore, pore is connected with pressure line 10, and pressure line 10 passes upper end cover 2 and is connected with air feed equipment 12.Be sealed and matched to making between pressurizing piston and the cylindrical shell 1 after 9 inflations of gas-flow closure circle during work; When needing cleaning, dismounting, 9 venting get final product to the gas-flow closure circle.
In addition, the lower end of pressurizing piston can also be provided with the circular distribution plate 11 that is formed by multilayer stainless (steel) wire sintering.
Should be noted that at last; above content is only in order to the explanation the technical solution of the utility model; but not to the restriction of the utility model protection domain; the simple modification that those of ordinary skill in the art carries out the technical solution of the utility model or be equal to replacement does not all break away from the essence and the scope of technical solutions of the utility model.
Claims (4)
1. chromatographic column with pressurizing piston, comprise cylindrical shell (1), be fixedly connected on the upper end cover (2) of cylindrical shell (1) upper end by flange (13), be arranged at the cup dolly (3) of cylindrical shell (1) lower end, be positioned at the pressurizing piston that cylindrical shell (1) cooperates with cylindrical shell (1) inner wall sealing, be connected in the feed pipe (4) of pressurizing piston upper end, described cup dolly (3) is provided with discharge opening (5), described pressurizing piston is provided with charging aperture corresponding to described feed pipe (4), it is protruding that described upper end cover (2) is passed on the top of described feed pipe (4), it is characterized in that: described feed pipe (4) is for having externally threaded round tube, the extension of described feed pipe (4) is arranged with and is used to drive the drive nut that feed pipe (4) moves up and down, described upper end cover (2) is provided with reducing motor (6), and described reducing motor (6) is connected with described drive nut by transmission mechanism.
2. according to the described chromatographic column of claim 1 with pressurizing piston, it is characterized in that: the ammeter (7) that also comprises column, fixedly connected with described pressurizing piston in the lower end of described ammeter (7), it is protruding that described upper end cover (2) is passed on the top of described ammeter (7), and described ammeter (7) is provided with indicating graduation.
3. according to claim 1 or 2 described chromatographic columns with pressurizing piston, it is characterized in that: described pressurizing piston comprises the gas-flow closure circle (9) of piston plate (8) and annular, the circumferential surface of described piston plate (8) has mounting groove, described gas-flow closure circle (9) is arranged in the described mounting groove, described gas-flow closure circle (9) has pore, described pore is connected with pressure line (10), and described pressure line (10) passes described upper end cover (2) and is connected with air feed equipment (12).
4. according to the described chromatographic column with pressurizing piston of claim 3, it is characterized in that: the lower end of described pressurizing piston is fixedly connected with the circular distribution plate (11) that is formed by multilayer stainless (steel) wire sintering.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2011200837338U CN201988227U (en) | 2011-03-28 | 2011-03-28 | Chromatographic column with pressurizing piston |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2011200837338U CN201988227U (en) | 2011-03-28 | 2011-03-28 | Chromatographic column with pressurizing piston |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN201988227U true CN201988227U (en) | 2011-09-28 |
Family
ID=44664732
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN2011200837338U Expired - Fee Related CN201988227U (en) | 2011-03-28 | 2011-03-28 | Chromatographic column with pressurizing piston |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN201988227U (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107519667A (en) * | 2017-09-29 | 2017-12-29 | 江苏汉邦科技有限公司 | A kind of new low clearance chromatography rod structure |
| CN115105859A (en) * | 2022-06-08 | 2022-09-27 | 上海金鑫生物科技有限公司 | Self-adaptive sealed chromatographic column |
-
2011
- 2011-03-28 CN CN2011200837338U patent/CN201988227U/en not_active Expired - Fee Related
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107519667A (en) * | 2017-09-29 | 2017-12-29 | 江苏汉邦科技有限公司 | A kind of new low clearance chromatography rod structure |
| CN115105859A (en) * | 2022-06-08 | 2022-09-27 | 上海金鑫生物科技有限公司 | Self-adaptive sealed chromatographic column |
| CN115105859B (en) * | 2022-06-08 | 2024-03-19 | 上海金鑫生物科技有限公司 | Self-adaptive sealed chromatographic column |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| C17 | Cessation of patent right | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20110928 Termination date: 20140328 |