CN201782878U - Transdermal iontophoretic eyecup electrode - Google Patents
Transdermal iontophoretic eyecup electrode Download PDFInfo
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- CN201782878U CN201782878U CN2010202630934U CN201020263093U CN201782878U CN 201782878 U CN201782878 U CN 201782878U CN 2010202630934 U CN2010202630934 U CN 2010202630934U CN 201020263093 U CN201020263093 U CN 201020263093U CN 201782878 U CN201782878 U CN 201782878U
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- eyecup
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- iontophoresis
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Abstract
The transdermal iontophoretic eyecup electrode is matched with an iontophoresis instrument; the pharmaceutical ion introduction method specially used at the eye part is clinically called as an eye-cup method, and the introduction efficiency of the eye-cup method is more than ten times higher than that of the lining method; the transdermal iontophoretic eyecup electrode is nontoxic, acid and alkali resistant and solvent resistant, is safe in use, simple and convenient, comfortable, firm in fixation, and waterproof, and assists the patient to open eyes for ion introduction; the transdermal iontophoretic eyecup electrode comprises eyecups 1, eye shields 2, cup holders 3, nose buckles 4, a headband 5, electrodes 6 and an eyelid retracting ring 17; and the transdermal iontophoretic eyecup electrode is characterized in that the eyecups 1 are connected with the eye shields 2 in a splicing manner; the electrodes 6 are respectively introduced into the eyecups 1 via the walls of the eyecups 1; the two eyecups 1 are respectively mounted on the two cup holders 3; nose buckle holes 16 on the inner sides of the two cup holders 3 are respectively connected with the nose buckles 4; headband holes 15 on the outer sides of the two cup holders are connected with both ends of the headband 5 to form a whole; and the eyelid retracting ring 17 serves as an independent component for the transdermal iontophoretic eyecup electrode.
Description
Technical field
This utility model relates to a kind of transdermal administration iontophoresis eyecup electrode assembly, belongs to medical instruments field.
Background technology
Transdermal administration iontophoresis technology, its principle is by direct current or the DC electric field to human body safety low, that intermediate frequency (half-wave) ion introducing apparatus produces, in the mode that the same sex is repelled each other, there is a natural attraction between the sexes, make medicine ion electronegative under medicine ion positively charged under the anelectrode or the negative electrode, see through skin or mucomembranous surface and enter human body, reach therapeutical effect, not injured skin and mucosa.
The transdermal administration technology is nearly in the world more than 20 years just new developing technology.China's pharmacopeia does not still have the relevant medicine and the method for inspection.But medicine ion imports the short saturating technology of the physics that belongs to transdermal administration, and it also is one of physical therapy technology, and the existing bicentenary history of physical therapy technology, owing to the restriction of equipment and other reasons, medicine ion imports and does not grow up, and clinical use is few.At present, medicine ion imports the general liner method of using, and promptly soaks sticking medicinal liquid with the cotton liner, is placed between electrode and the skin surface to import.If use eye-cup method importings of opening eyes, than the medication amount of liner method importing Duo 16～19 times (" Physical Therapy ". Guo Wanxue. Beijing. People's Health Publisher .1984 .1020 page or leaf), help improving curative effect.Till 2010, still there are not eyecup electrode commodity on the China market, there is not eyecup electrode patent yet, just on " Physical Therapy " books, be decorated with the eyecup electrode pattern of image height foot wineglass sample, be coated in the rim of a cup leakproof with vaseline, make electrode with platinum, carbon, titanium, rustless steel, gold, silver, iridium, vanadium etc., require patient's importing of opening eyes.Through test, platinum is safest as electrode, and still, the patient uses above-mentioned eyecup electrode, no matter take to face upward the position or bow the position of bowing, all is difficult to fixing and leakproof, and is also uncomfortable, is difficult to become commodity.
This utility model provides a kind of transdermal administration iontophoresis eyecup electrode, can better address the above problem, accomplish safe, nontoxic, acidproof, alkaline-resisting, anti-solvent, do not leak, transparent, comfortable, easy and simple to handle, auxiliary opening eyes, help improving medicine ion and import efficient.
Summary of the invention
This utility model by eyecup 1, eyeshield 2, glass stand 3, nose buckle 4, headband 5, electrode 6, medicine-pouring hole 8, medicine stopple 9 and open eyelid ring 17 and form, it is characterized in that, eyecup 1 is connected with eyeshield 2 sleeves, electrode 6 is fed in the eyecup by the wall of eyecup 1, two eyecups 1 are installed in respectively on two glass stands 3, the nose button hole 16 of two glass stand 3 inboards connects nose button 4, the headband hole 15 in two glass stand 3 outsides connects headband 5 two ends, make it to become one, opening eyelid ring 17 is independent ingredients that medicine ion imports the eyecup electrode.
Eyecup 1 is a tazza shape device that is used to take up medicinal liquid, with nontoxic, acidproof, alkaline-resisting, anti-solvent, transparent rigid plastics manufacturing, guarantees patient safety; Transparent, be convenient to observe the importing situation, provide convenience from line operate for medical personnel and patient; The oral area of eyecup 1 has a circle flanging 13, and its shape adapts to the eye socket skin surface, is convenient to leakproof; There is medicine-pouring hole 7 upper surface of eyecup 1, is used to inject medicinal liquid and inserts medicine stopple 8, guarantees that medicinal liquid does not outflow; Electrode hole 9 is arranged below the wall of eyecup 1, be used to insert electrode 6.
Electrode 6 is welded to form by platinum wire 12, plastic skin lead 11 and socket 10.Platinum wire 12 1 ends contact with medicinal liquid by the inside that electrode hole 9 inserts eyecup 1; The other end is connected with ion introducing apparatus with socket 10 by plastic skin lead 11 outside eyecup 1, and to the medicinal liquid power supply of eyecup 1 inside, the drives medication ion sees through eyelid skin, mucosa and eyeball surface and enters ophthalmic.The slit of electrode hole 9 seals with nontoxic glue.
The nontoxic silica gel of eyeshield 2 usefulness is made, and is soft and approach, flexible, is used to connect eyecup 1, and attached to eye, is the leak-proof device of medicinal liquid.The flanging 13 of the flanging cover 14 tight socket eyecups 1 of one side, the another side close attachment makes it not leak medicinal liquid at the eye socket skin surface.
Glass stand 3 eyecup 1 that is used to pack into, there is nose button hole 16 inboard, and nose button 4 is used to peg graft.There is headband hole 15 in the outside, is used for cross-under headband 5.
Nose button 4 usefulness flexible plastics are made, and nose button hole 16 is inserted at two ends, and right and left eyes glass stand 3 is linked together.The nose button of different size can be adjusted the distance of right and left eyes cup 1, to adapt to the width of eyes.
Headband 5 usefulness elastic cords are made, and its two ends cross-under is in the headband hole 15 of left and right sides glass stand 3, and the head that is enclosed within that can be easy is gone up fixedly eyecup 1.Adjust the length of headband 5, can make eyeshield 2 close attachment skins, feel comfortable, the leakproof effect is also arranged.
Open eyelid ring 17 nontoxic silica gel of usefulness finer wire outsourcing or plastic productions, can strut palpebra inferior on eyelid skin surface, simple and safe, even the little closed eyes of patient also can be the state of opening eyes, make medicinal liquid soak eyeball surface, reach the importing of opening eyes.
Use transdermal administration iontophoresis eyecup electrode can produce following beneficial effect.
(1) makes things convenient for the patient.Change the traditional administering mode have an injection, infuse, take medicine, patient's treatment of can under doctor's guidance, being in.This myopia, amblyopia patient and head of a family thereof to study, working time anxiety provides convenience, and also the control to China's myopia more than 600,000,000 and 2,000 ten thousand amblyopia eyes is significant.
(2) enter the eye dose many, slow release effect is arranged.The dose ratio that the enters eye height of having an injection, infuse, take medicine helps treatment.Experiment shows that medicine ion imports and enters the high several times of dose of human body, tens of times even hundreds of times than eye drip, eye-douche, subconjunctival injection, ball side or retrobulbar injection; Eye-cup method is higher tens times than liner method medicine import volume, import the degree of depth can reach retina (" Physical Therapy ". Guo Wanxue. Beijing. People's Health Publisher .1984 .1020 page table 14-89-1, table 14-89-2,1022 page table 14-89-3).And, importing mainly be the effective ingredient of medicine, a large amount of solvents and substrate do not enter in the body; Because the effect of DC electric field, medicine ion can form " ion heap " outside cell membrane, and retention time is long, and is very fast through the blood drainage that circulates unlike having an injection, infuse, take medicine, so, can curative effect lasting.
(3) avoid untoward reaction.Having an injection, infuse, take medicine, it is too high to produce blood drug level, causes the human body untoward reaction easily.And the ocular drug iontophoresis this problem can not occur.Having an injection, infusing, taking medicine the first pass effect of liver also to occur, and drug metabolism is strengthened, and absorbs and reduces; The factor affecting such as being subjected to the interior pH value of digestive tract, food, transhipment time of taking medicine are big, hinder drug absorption, and this all can cause the treatment effect to descend.
(4) transparent eyecup is convenient to observe inside and outside situation, handled easily.
(5) both can simple eye administration, but also eyes administration, to sick eyeball target administration, flexibly.
Description of drawings
Be described further below in conjunction with accompanying drawing.
Fig. 1 is the axonometric chart of transdermal administration iontophoresis eyecup electrode.By eyecup 1, eyeshield 2, glass stand 3, nose buckle 4, headband 5, electrode 6, medicine stopple 7, medicine-pouring hole 8, electrode hole 9(please see Figure 2), socket 10, plastic skin lead 11, platinum wire 12, flanging 13, flanging cover 14, headband hole 15, nose button hole 16, open eyelid ring 17(and please see Figure 6) form.
Fig. 2 is the axonometric chart of an eyecup 1.Medicine-pouring hole 8, electrode hole 9, flanging 13 are wherein arranged.
Fig. 3 is the axonometric chart of an eyeshield 2.Flanging cover 14 is wherein arranged.
Fig. 4 is the axonometric chart of a glass stand 3.Headband hole 15, nose button hole 16 are wherein arranged.
Fig. 5 is eyecup 1 and the eyeshield 2 belled drawings in side sectional elevation that dissect along the a-a line.Flanging 13, flanging cover 14, eyecup 1 and eyeshield 2 are wherein arranged.
Fig. 6 is out eyelid ring 17.
Fig. 7 is that the part of electrode 6 connects to form.Socket 10, plastic skin lead 11, platinum wire 12 are wherein arranged.
Embodiment
Eyecup 1 and medicine-pouring hole 8 thereof, electrode hole 9, flanging 13; Eyeshield 2 and flanging cover 14 thereof; Glass stand 3 and headband hole 15 thereof, nose button hole 16; Nose button 4; Medicine stopple 7 parts such as grade, all through making mould, injection moulding is made.
Electrode 6 is welded to form by platinum wire 12, plastic skin lead 11 and socket 10.Platinum wire one end inserts eyecup 1 inside by electrode hole 9 ecto-entads, and insertion portion is along being poured on the eyecup wall, and electrode hole 9 outsides seal with nontoxic glue.
The flanging cover 14 of eyeshield 2 is inserted in the flanging 13 of eyecup 1.
Eyecup 1 is installed into glass stand 3.
Nose button hole 16 with nose button 4 two ends insertion glass stand connects left and right sides glass stand 3.
Headband 5 two ends are penetrated the headband hole 15 of left and right sides glass stand 3 respectively.
Open eyelid ring 17 usefulness finer wires and curve ring-type, welding point, the surface coats non-toxic plastic or silica gel.Before wearing eyecup, will open 17 supports of eyelid ring on last palpebra inferior outer skin, expose eyeball, and be and force the state of opening eyes, wear transdermal administration iontophoresis eyecup electrode again.
Claims (8)
1. transdermal administration iontophoresis eyecup electrode, by eyecup (1), eyeshield (2), glass stand (3), nose button (4), headband (5), electrode (6), medicine-pouring hole (8), medicine stopple (9) and open eyelid ring (17) and form, it is characterized in that, eyecup (1) is connected with eyeshield (2) sleeve, electrode (6) is fed in the eyecup by the wall of eyecup (1), two eyecups (1) are installed in respectively on two glass stands (3), the inboard nose button hole (16) of two glass stands (3) connects nose button (4), the headband hole (15) in two glass stands (3) outside connects headband (5) two ends, make it to become one, opening eyelid ring (17) is the independent ingredient that medicine ion imports the eyecup electrode.
2. transdermal administration iontophoresis eyecup electrode according to claim 1, it is characterized in that eyecup (1) be can take up medicinal liquid, nontoxic, acidproof, alkaline-resisting, anti-solvent, transparent cup, rim of a cup is the flanging (13) that is suitable for the eye surface configuration, medicine-pouring hole (8) is arranged at the top on cup surface, and the following middle side part of wall of cup has electrode hole (9).
3. transdermal administration iontophoresis eyecup electrode according to claim 1 is characterized in that eyeshield (2) is a silica gel, and is softish, nontoxic, has flanging cover (14).
4. transdermal administration iontophoresis eyecup electrode according to claim 1 is characterized in that glass stand (3) is the approximate ellipsoidal made by rigid plastics, the device of the eyecup of can packing into, and there is nose button hole (16) inboard, and there is headband hole (15) in the outside.
5. transdermal administration iontophoresis eyecup electrode according to claim 1 is characterized in that nose button (4) made by flexible plastic, and nose button hole (16) can be inserted in two ends.
6. transdermal administration iontophoresis eyecup electrode according to claim 1 is characterized in that headband (5) makes of elastic cord.
7. transdermal administration iontophoresis eyecup electrode according to claim 1 is characterized in that electrode (6) is welded by platinum wire (12), plastic sheath lead (11) and socket (10).
8. transdermal administration iontophoresis eyecup electrode according to claim 1 is characterized in that medicine stopple (9) made by nontoxic silica gel.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2010202630934U CN201782878U (en) | 2010-07-20 | 2010-07-20 | Transdermal iontophoretic eyecup electrode |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2010202630934U CN201782878U (en) | 2010-07-20 | 2010-07-20 | Transdermal iontophoretic eyecup electrode |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN201782878U true CN201782878U (en) | 2011-04-06 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN2010202630934U Expired - Fee Related CN201782878U (en) | 2010-07-20 | 2010-07-20 | Transdermal iontophoretic eyecup electrode |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105534638A (en) * | 2016-01-31 | 2016-05-04 | 杭州睩客科技有限公司 | Volatile medicine dosing device with eye health caring effect |
| CN109172134A (en) * | 2018-10-29 | 2019-01-11 | 王欣怡 | A kind of multifunction nursing eyeshade used after operated eye |
-
2010
- 2010-07-20 CN CN2010202630934U patent/CN201782878U/en not_active Expired - Fee Related
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105534638A (en) * | 2016-01-31 | 2016-05-04 | 杭州睩客科技有限公司 | Volatile medicine dosing device with eye health caring effect |
| CN109172134A (en) * | 2018-10-29 | 2019-01-11 | 王欣怡 | A kind of multifunction nursing eyeshade used after operated eye |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| C17 | Cessation of patent right | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20110406 Termination date: 20130720 |