CN201710707U - Titanium alloy femoral stem implant with hydroxyapatite coating - Google Patents
Titanium alloy femoral stem implant with hydroxyapatite coating Download PDFInfo
- Publication number
- CN201710707U CN201710707U CN 201020255769 CN201020255769U CN201710707U CN 201710707 U CN201710707 U CN 201710707U CN 201020255769 CN201020255769 CN 201020255769 CN 201020255769 U CN201020255769 U CN 201020255769U CN 201710707 U CN201710707 U CN 201710707U
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- CN
- China
- Prior art keywords
- hydroxyapatite
- titanium alloy
- femoral stem
- bone
- preparation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2/30767—Special external or bone-contacting surface, e.g. coating for improving bone ingrowth
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2002/30001—Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
Abstract
The utility model relates to a titanium alloy femoral stem implant with hydroxyapatite coating and is characterized in that a hydroxyapatite coating is arranged on a titanium alloy femoral stem implant, and the thickness of the hydroxyapatite coating ranges from 25 Mum to 85 Mum, preferably 55 Mum. The utility model has the advantage that based on the osteoinductive bioactivity of the hydroxyapatite (HA) material, the bone is directly settled on the surface of the HA implant to form chemical and biological bonding, so that the implant is fixed stably and reliably inside the bone.
Description
[technical field]
This utility model relates to technical field of medical instruments, specifically, is a kind of titanium alloy femoral stem that contains hydroxyapatite layer.
[background technology]
Chinese patent publication number CN1416911 relates to the preparation method of the compound osteocomma of hydroxyapatite-ultra-high molecular weight polyethylene, the present invention relates to the preparation method of the compound osteocomma of a kind of hydroxyapatite-ultra-high molecular weight polyethylene.As the artificial bone, hydroxyapatite has good biocompatibility, bone affinity, and its shortcoming is that fragility is big, can not be crooked; And ultra-high molecular weight polyethylene has characteristics such as rub resistance, damping and supporting role are good, the more important thing is its thin slice when 80 ℃ of left and right sides, can be crooked arbitrarily.Therefore, by hydroxyapatite and the ultra-high molecular weight polyethylene compound osteocomma of the formed hydroxyapatite-ultra-high molecular weight polyethylene advantage of the two that possessed them simultaneously that is combined with each other, but still there is not a kind of feasible preparation method so far.The invention provides a kind of preparation method, promptly choose the hydroxyapatite of certain thickness super high molecular weight thin slice and certain granules degree is put into mould pressing under uniform temperature and pressure.The present invention becomes possibility for the compound osteocomma of hydroxyapatite-ultra-high molecular weight polyethylene enters clinical practice.
Chinese patent publication number CN1397518 relates to the preparation method of nanometer hydroxyapatite/aluminium oxide composite boilogical ceramic, the preparation method of a kind of nanometer hydroxyapatite/aluminium oxide composite boilogical ceramic, key step is: (1) has adopted the method deposited hydroxyl apatite of physics, the nanometer hydroxyapatite predecessor of preparation stoichiometric proportion, guaranteed that deposit is the hydroxyapatite of stoichiometric proportion, and used mould plate technique; (2) the hydroxyapatite predecessor is a nanoscale, the method of employing agitating heating prepares the nanometer hydroxyapatite predecessor of stoichiometric proportion, heating-up temperature is 20-100 ℃, and the concentration of calcium hydroxide suspension is 0.001~4mol/L, and concentration of phosphoric acid is 0.001~5mol/L; (3) hydroxyapatite predecessor supersound process is made the suspension that concentration is 10-5-10-2mol/L, the method that alumina formwork is directly soaked deposits hydroxyapatite in alumina formwork, promptly obtain being orientated consistent nanometer hydroxyapatite/aluminium oxide composite boilogical ceramic.
Chinese patent publication number CN1451691 relates to polylactic acid from modifying hydroxyapatite/polylactic acid composite and preparation method, the invention provides a kind of polylactic acid from modifying hydroxyapatite/polylactic acid composite and preparation method, this method at first adopts identical with the matrices of composite material construction unit and polylactic acid modified hydroxyapatite that molecular weight is less, to carry out through the higher polylactic acid matrix of the hydroxy phosphorous stone modified and relative molecular weight then compound, by absorption, dry, roller refines, compression molding makes composite.Method technology of the present invention simply, is not introduced other toxic inorganic or organic molecule, and the initial bending strength of prepared composite is up to 114~210.2MPa, good biocompatibility.
Chinese patent publication number CN1446588 relates to glass-base nanometer hydroxylapatite biology cement and preparation method thereof, this invention relates to a kind of biologically active, the bone bonding agent of solidification forming (claiming biological cement again) voluntarily, it is a kind of multi-phase composites, is made up of mutually with nano hydroxyl phosphorite crystal mutually phosphate glass.Phosphate glass is given biological cement mutually with good biocompatibility and biological activity, after distiller liquor mixes, has the performance that viscosity increases gradually, and the mixture of formation finally can solidify voluntarily, bonding bone molectron.The product ammonium calcium phosphate hydras of curing reaction generates the nascent state hydroxyapatite through the effect of Human Physiology simulated solution during mixing, to the formation of new bone and the inducing action of having grown.The present invention is used for the bonding of the damaged repairing of the bone of surgical operation and artificial bone and natural bone, and higher compressive resistance is arranged, and has the function of anticancer growth.
Chinese patent publication number CN1047627 relates to hydroox apatite artificial bone material preparation method, the invention belongs to hydroox apatite artificial bone material technology of preparing, with calcium oxide and phosphoric acid is the raw material synthesizing hydroxylapatite, make graininess or the block artificial bone material of human body bone through forming and sintering again, raw material cheaply is easy to get, and technology is advanced simple.Reliable product quality is suitable for, and institute's prepared material is used through hospital orthopedics and hands surgical clinical, obtains satisfactory result, does not have and loses the example discovery.This mechanical strength height, biocompatibility and skeletonization are good.
Chinese patent publication number CN1190136 relates to the preparation method of the reinforced ion beam-deposited hydroxyl apatite coating of medical implant, the present invention relates to a kind of preparation method of reinforced ion beam-deposited hydroxyl apatite coating of medical implant, this method is a sputtering target with the sintered ceramic of 50% hydroxyapatite.At first clean with Ar ion bom bardment sample, maintaining under the steam partial pressure with the sputtering from ion beam emission target then, in substrate sample surface sputtering film forming, be aided with high energy Ar ion beam bombardment substrate sample simultaneously, membrane sample is taken out from vacuum chamber, be heated to 380~420 ℃, in humid air, anneal.Advantages such as the adhesion that the coating of the present invention preparation has film and substrate is strong, and the density height of film own, biocompatibility are good.
Chinese patent publication number CN1370508 relates to cranial bone implant of hydroxyapatite sprayed biological titanium, a kind of cranial bone implant of hydroxyapatite sprayed biological titanium, it is made up of hydroxylapatite powder, biological titanium sheet, biological titanium screw, and hydroxylapatite powder 1 covers biological titanium sheet 2 surfaces fully; Cranial bone implant of hydroxyapatite sprayed biological titanium is a semicircular arc, diameter: 8~30cm, and camber is: 0.5~10cm, thickness is: 0.5~1.5mm; There is fixing hole 3 outer ring on the arc surface, and inner ring is drain growth hole 4; Biological titanium screw passes fixing hole 3 and fixes with skull.It has anti-impact force by force, moulding easily, the characteristics that can and merge from the body bone photo.
Chinese patent publication number CN101229392 relates to Inversly crystallized collagen-hydroxyl apatite bone repair materials and preparation method thereof, the present invention relates to a kind of Inversly crystallized collagen-hydroxyl apatite bone repair materials and preparation method thereof.The hydroxyapatite microcrystal is scattered in collagen swelling liquid, adjust pH value between the 8-12, by Inversly crystallized process, collagen, hydroxyapatite are separated out simultaneously, obtain material of the present invention by cryodesiccated process again, the material of the present invention's preparation, be made of Inversly crystallized method, the crystallization of hydroxyapatite crystal independence is between collagen fiber, and the nucleus of hydroxyapatite crystal is a hydroxyapatite, its space structure has three-dimensional porous construction features, and the aperture is 50~500 μ m.
Chinese patent publication number CN101229394 relates to titanium alloy-collagen-hydroxyl apatite bone repairing material and preparation method thereof, the present invention relates to a kind of titanium alloy-collagen-hydroxyl apatite bone repairing material and preparation method thereof.At first make up the netted support of titanium alloy, again the hydroxyapatite microcrystal is scattered in collagen swelling liquid with certain form by three-dimensional reconstruction and rapid shaping technique.The netted skeleton of titanium alloy is immersed in the collagen-hydroxyapatite dispersion liquid, adjust pH value between the 8-12, collagen, hydroxyapatite are separated out simultaneously, cover the netted rack surface of titanium alloy, obtain material of the present invention by cryodesiccated process again, in the material of the present invention's preparation, hydroxyapatite-collagen-based composite is distributed in the surface of the netted support girder of titanium alloy.
Chinese patent publication number CN101229393 relates to collagen-chitin-hydroxyl apatite bone repairing material and preparation method thereof, the present invention relates to a kind of collagen-chitin-hydroxyl apatite bone repairing material and preparation method thereof.At first the hydroxyapatite microcrystal is scattered in the chitosan swelling liquid, again hydroxyapatite-chitosan dispersion liquid is made an addition to collagen swelling liquid, adjust between pH value to 8~12, make collagen, chitosan and hydroxyapatite are separated out simultaneously, obtain material of the present invention by cryodesiccated process again, in the material of the present invention's preparation, in collagen-chitin-hydroxyl apatite bone repairing material, hydroxyapatite is positioned in the middle of the collagen fiber, chitosan is distributed in the polarity group of collagen fiber, collagen distribution is on the surface of integral material, and material has three-dimensional porous construction features.
Hydroxyapatite, Hydroxyapatite is called for short: HA, physicochemical properties: fusing point: 1650 ℃, proportion: 3.16g/cm, dissolubility: 0.4ppm, Ca/P:1.67, crystal structure: hexaplanar, product specification: powder, porous particle, bulk (nonstandard typing) product, application: bone alternate material, shaping and esthetic surgery, tooth section, chromatography purification, calsium supplement, hydroxyapatite, claiming hydroxyapatite again, is apatite calcium (Ca
5(PO
4)
3Mineralizing naturally (OH)).But often write as (Ca
10(PO
4)
6(OH)
2) form with outstanding it be dimeric: hydroxyl and apatite.The OH-base can be replaced by fluoride, chloride and carbanion, generates fluorine-based apatite or chloro apatite.Skeleton up to 50% all is that the inorganic hydroxyapatite by even composition constitutes.Be widely used in making the most advanced and sophisticated new material of approval tooth or skeleton composition at present.Functional effect: healthy brilliant white, remove dental plaque, improve the gingiva problem, prevent decayed tooth, fresh breath, method for making: can be by Ca (PO
4)
2And CaCO
3At high temperature react in the ratio of drafting and to inject high-pressure steam simultaneously, powder is through NH
4Cl solution washing after drying forms, and divides two kinds of porous type and dense forms, and the former is that powder foaming back prepares in 1250 ℃ of sintering, forms in 1250 ℃ of sintering after latter's molding.Distribute: extensively be present in human body and the Lac Bovis seu Bubali, mainly be distributed in the human body in skeleton and the tooth, mainly be distributed in casein micelle and the milk surum in the Lac Bovis seu Bubali.Therefore, often HA is coated in the mechanical property surface of biologically inert metal surface such as titanium or titanium alloy preferably, obtains having concurrently the composite of both advantages.
The research that hydroxyapatite bioactive material is used as the prosthese coating starts from the beginning of the seventies, just formally is used for the clinical hip prosthesis that fixes up in December, 1986.Domestic research to the HA material starts from recent years, many HA as the damaged packing material of bone, HA is observed its research to the prosthese fixed effect as coating, this experiment still belongs to the first time at home.
[utility model content]
The purpose of this utility model is to overcome the deficiencies in the prior art, and a kind of titanium alloy femoral stem that contains hydroxyapatite layer is provided.
The purpose of this utility model is achieved through the following technical solutions:
A kind of titanium alloy femoral stem that contains hydroxyapatite layer is characterized in that, a hydroxyapatite layer is set on the titanium alloy femoral stem.
The thickness of described hydroxyapatite layer is 25~85 μ m, is preferably 55 μ m;
A kind of preparation method that contains the titanium alloy femoral stem of hydroxyapatite layer is: sintering one deck hydroxyapatite layer on titanium alloy femoral stem surface.
Compared with prior art, good effect of the present utility model is:
Utilize good biological activity---the bone guided of HA material, make bone directly be deposited on the surface of HA prosthese, form chemical and biological combination, thereby it is stable and fixing reliably that prosthese is obtained in bone.
[description of drawings]
Fig. 1 structural representation of the present utility model;
Label in the accompanying drawing is respectively: 1, hydroxyapatite layer, 2, the titanium alloy femoral stem.
[specific embodiment]
Be described further below in conjunction with accompanying drawing.
See also accompanying drawing 1, a kind of titanium alloy femoral stem that contains hydroxyapatite layer is characterized in that, a hydroxyapatite layer 1 is set on titanium alloy femoral stem 2.
The thickness of described hydroxyapatite layer is 35 μ m;
A kind of preparation method that contains the titanium alloy femoral stem of hydroxyapatite layer is: sintering one deck hydroxyapatite layer on titanium alloy femoral stem surface.
See also accompanying drawing 1, a kind of titanium alloy femoral stem that contains hydroxyapatite layer is characterized in that, a hydroxyapatite layer 1 is set on titanium alloy femoral stem 2.
The thickness of described hydroxyapatite layer is 55 μ m;
A kind of preparation method that contains the titanium alloy femoral stem of hydroxyapatite layer is: sintering one deck hydroxyapatite layer on titanium alloy femoral stem surface.
Embodiment 3
See also accompanying drawing 1, a kind of titanium alloy femoral stem that contains hydroxyapatite layer is characterized in that, a hydroxyapatite layer 1 is set on titanium alloy femoral stem 2.
The thickness of described hydroxyapatite layer is 65 μ m;
A kind of preparation method that contains the titanium alloy femoral stem of hydroxyapatite layer is: sintering one deck hydroxyapatite layer on titanium alloy femoral stem surface.
Embodiment 4
See also accompanying drawing 1, a kind of titanium alloy femoral stem that contains hydroxyapatite layer is characterized in that, a hydroxyapatite layer 1 is set on titanium alloy femoral stem 2.
The thickness of described hydroxyapatite layer is 85 μ m;
A kind of preparation method that contains the titanium alloy femoral stem of hydroxyapatite layer is: sintering one deck hydroxyapatite layer on titanium alloy femoral stem surface.
The above only is a preferred implementation of the present utility model; should be pointed out that for those skilled in the art, under the prerequisite that does not break away from this utility model design; can also make some improvements and modifications, these improvements and modifications also should be considered as in the protection domain of the present utility model.
Claims (3)
1. a titanium alloy femoral stem that contains hydroxyapatite layer is characterized in that, a hydroxyapatite layer is set on the titanium alloy femoral stem.
2. a kind of titanium alloy femoral stem that contains hydroxyapatite layer as claimed in claim 1 is characterized in that the thickness of described hydroxyapatite layer is 25~85 μ m.
3. a kind of titanium alloy femoral stem that contains hydroxyapatite layer as claimed in claim 2 is characterized in that the thickness of described hydroxyapatite layer is 55 μ m.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
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CN 201020255769 CN201710707U (en) | 2010-07-09 | 2010-07-09 | Titanium alloy femoral stem implant with hydroxyapatite coating |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
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CN 201020255769 CN201710707U (en) | 2010-07-09 | 2010-07-09 | Titanium alloy femoral stem implant with hydroxyapatite coating |
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CN201710707U true CN201710707U (en) | 2011-01-19 |
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CN 201020255769 Expired - Fee Related CN201710707U (en) | 2010-07-09 | 2010-07-09 | Titanium alloy femoral stem implant with hydroxyapatite coating |
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-
2010
- 2010-07-09 CN CN 201020255769 patent/CN201710707U/en not_active Expired - Fee Related
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Legal Events
Date | Code | Title | Description |
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C14 | Grant of patent or utility model | ||
GR01 | Patent grant | ||
C17 | Cessation of patent right | ||
CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20110119 Termination date: 20110709 |