CN201624674U - 3D imaging device for biological tissue - Google Patents
3D imaging device for biological tissue Download PDFInfo
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- CN201624674U CN201624674U CN 201020146903 CN201020146903U CN201624674U CN 201624674 U CN201624674 U CN 201624674U CN 201020146903 CN201020146903 CN 201020146903 CN 201020146903 U CN201020146903 U CN 201020146903U CN 201624674 U CN201624674 U CN 201624674U
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Abstract
The utility model discloses a 3D imaging device for a biological tissue, which mainly comprises a circular gear, a curved ultrasonic array, a bowl-shaped curved shell, an ultrasonic coupling fluid, a protecting film, a horn antenna, a waveguide, a microwave generator, a frequency divider, a data acquisition circuit, a pre-processing circuit, a stepping motor, a drive, a digital I/O card, a computer and a display. The working process of the device comprises: the tissue to be tested generates thermoaeoustic signals through the pulse microwave radiation and then is received by the curved ultrasonic array, and finally collected by the computer; the drive drives the curved ultrasonic array around the tissue to be tested to turn to the next position; the collecting-to-turning step is repeated until enough all-round thermoaeoustic signals are received; the computer calculates and rebuilds the 3D thermoaeoustic image of the tissue to be tested. The 3D imaging device for the biological tissue can quickly and exactly realize the 3D thermoaeoustic imaging of the biological tissue, in particular to the detection of the early breast cancer and the craniocerebral injury.
Description
Technical field
This utility model relates to biomedical measurement and technical field of medical instruments, is specifically related to a kind of biological tissue's three-dimensional image forming apparatus that is used for.
Background technology
Thermal acoustic imaging is a kind of based on biological tissue's inside microwave absorption difference with ultrasonic vehicular harmless biomedical image technology, it effectively combines the advantage of the high-penetration degree of depth of the high-contrast of pure microwave imaging and pure acoustics imaging, can realize the tissue image of centimetre magnitude investigation depth and micron dimension imaging precision, be considered to develop into the medical imaging technology of a new generation, become the method for early diagnosis of very effective breast carcinoma and other lesion tissue.The system of thermal acoustic imaging system generally adopts single wide-band transducer at present, common 360 ° of omnibearing stepping rotating machinery scannings, to obtain the hot acoustical signal of different directions, reconstruct the microwave absorption distribution of tissue again through complicated algorithm, have that the complicated poor stability of system structure, amount of calculation are big, shortcoming such as long expends time in, obviously there is sizable limitation in actual applications, can't satisfies the demand of actual clinical.
Summary of the invention
The purpose of this utility model provides a kind of biological tissue's three-dimensional image forming apparatus that is used for, and utilizes described device can realize the three-dimensional thermal acoustic imaging of biological tissue quickly and accurately.
For achieving the above object, this utility model adopts following technical scheme:
A kind of biological tissue three-dimensional image forming apparatus comprises that heat sound excites and sensing unit signal controlling and processing unit.
Described heat sound excite with sensing unit comprise circular gear, one or more arc ultrasonic array, in bowl-shape arc shell, protecting film, electromagnetic horn, waveguide and the microwave generator of ultrasonic coupling liquid are housed.The top exterior walls location of described bowl-shape arc shell is installed described circular gear with one heart, the sidewall of bowl-shape arc shell is inlayed the described arc ultrasonic array that radian and bowl-shape arc shell are complementary from the top to the bottom, the bottom of bowl-shape arc shell combines with described protecting film sealing; Described electromagnetic horn is equipped with in the below of protecting film.Described waveguide one end is connected with the electromagnetic horn bottom, and the other end is connected with described microwave generator.The lower edge of bowl-shape arc shell and the upper edge of electromagnetic horn are rotationally connected.
Described signal controlling and processing unit are made up of frequency divider, data acquisition circuit, pre-process circuit, motor, driver, digital I/O card, computer and display.
Described circular gear and motor are connected with a joggle.Described computer, digital I/O card, driver are connected with motor lead successively.Described digital I/O card also is connected with pre-process circuit, arc ultrasonic array lead successively.Described data acquisition circuit is connected with frequency divider, pre-process circuit and computer lead respectively.Described computer also is connected with the display lead.Described frequency divider is connected with described microwave generator lead.
As a kind of embodiment of the present utility model, described bowl-shape arc shell is inlayed a described arc ultrasonic array from the top to the bottom.When detecting, bowl-shape arc shell needs to center at least tested mammary gland Rotate 180 degree, just can obtain the three-dimensional hot acoustic image of complete data, and is consuming time long.
As another kind of embodiment of the present utility model, described bowl-shape arc shell is inlayed three or three the above arc ultrasonic array from the top to the bottom.Bowl-shape arc shell can obtain the three-dimensional hot acoustic image of complete data around the less angle of tested mammary gland rotation; But owing to adopted a plurality of arc ultrasonic array, cost is higher.
This utility model preferred embodiment is that described bowl-shape arc shell is inlayed two described arc ultrasonic array from the top to the bottom.This utility model more preferably two described arc ultrasonic array angles be 90 degree be embedded on the bowl-shape arc shell.Should preferably install when detecting, bowl-shape arc shell can obtain the three-dimensional hot acoustic image of complete data around tested mammary gland rotation 90; Detect weak point consuming time, cost is reasonable.
Certainly, it will be appreciated by those skilled in the art that in actual detected does not need under the complete data conditions, and above-mentioned bowl-shape arc shell only need be around the littler angle of tested mammary gland rotation.
Ultrasonic coupling liquid in order to prevent to detect in the bowl-shape arc shell flows out, above-mentioned heat sound excites with sensing unit and comprises that also one seals bonded circular elastic seal ring with bowl-shape arc shell top inner wall, described elastic seal ring can adopt as rubber, silica gel elastomeric material and make, and the internal diameter of sealing ring is less than the diameter of tested mammary gland.
Among a kind of embodiment of the present utility model, only comprise that a described heat sound excites and sensing unit and described signal controlling and processing unit, described device is specially adapted to the detection of one-sided breast.
Among the another kind of embodiment of device described in the utility model, comprise that two described heat sound excite and sensing unit and described signal controlling and processing unit.Frequency divider in described signal controlling and the processing unit simultaneously and two heat excite with microwave generator lead in the sensing unit and be connected; Motor in signal controlling and the processing unit and two heat sound excite with sensing unit in circular gear two kinds of connected modes are arranged: 1) motor simultaneously and two circular gears be connected with a joggle, then two bowl-shape arc shells rotate synchronously; 2) two circular gears are connected with a joggle with two motors respectively, and two described motors are connected with described driver lead simultaneously, and following two the bowl-shape arc shells of this connected mode can independent rotation.Described device is specially adapted to the detection of bilateral breast.
Device described in the utility model can also comprise the fixed cell that mainly is made of workbench, the coaxial manhole in one or two center of circle is arranged on the described workbench, be that a described heat sound excites and sensing unit under each described manhole, described circular gear and workbench are rotationally connected.Patient can the prostrate hot sound detection of accepting one-sided or bilateral breast on workbench.
Each arc ultrasonic array described in the utility model can contain 512,256 or 128 array elements, and the seam at quarter between the array element is wide to be 0.03mm.
Work process of the present utility model is:
1) tested biological tissue as mammary gland, cranium brain etc., enters and is immersed in the ultrasonic coupling liquid by the upper end open of arc shell, opens the nondestructive screening device;
2) microwave generator excites the pulse microwave that produces 1.2GHz to be coupled into waveguide, sees through the protecting film radiation through electromagnetic horn and inspire hot acoustical signal in tested biological tissue, and the while is through the pulse microwave trigger data acquisition circuit of frequency divider frequency division; Arc ultrasonic array receives hot acoustical signal, is translated into the signal of telecommunication and through after the pre-process circuit processing, advances computer by the data acquisition circuit collection;
3) gathered once hot acoustical signal after, computer sends digital signal to driver by digital I/O card, drive stepping motor realizes that a stepping rotates, and drives arc ultrasonic array by circular gear simultaneously and turns to next position around tested biological tissue;
4) repeating step 2 and 3;
5) after rotation sweep receives the hot acoustical signal in abundant orientation, computer reconstructs the three-dimensional hot acoustic image of tested biological tissue by calculating, is shown in real time or processing such as follow-up printing by display.
The beneficial effects of the utility model are:
(1) this utility model has effectively been realized the miniaturization and the practicability of system structure with the exciting and sensing integrated processing of three-dimensional thermal acoustic imaging.System's good portability and easy and simple to handle.
(2) supersonic array of the arcs of recesses structure that adopts of this utility model has first density height that shakes, location accurately and advantage such as machining is easy, can effectively improve the spatial resolution and the temporal resolution of imaging, realize the three-dimensional thermal acoustic imaging of biological tissue quickly and accurately, be specially adapted to the detection of breast carcinoma of early stage and craniocerebral injury.
(3) rotation sweep that only need carry out a direction can be realized three-dimensional thermal acoustic imaging, has effectively improved the mechanical stability of system and easy and simple to handle.
(4) sensing device of the present utility model is for doing the arcs of recesses structure of circular scanning, except that mammary gland, cranium brain, can be widely used in 3 D medical imaging field such as the growth of the biological tissue of irregular projective structure or toy and lesion detection.
Description of drawings
Fig. 1 is the primary structure sketch map of embodiment 1.
Fig. 2 excites structural representation with sensing unit for heat sound embodiment illustrated in fig. 1.
Fig. 3 excites vertical view with sensing unit for the heat sound that does not contain microwave generator shown in Figure 2.
Fig. 4 excites upward view with sensing unit for the heat sound that does not contain microwave generator shown in Figure 2.
Fig. 5 is the structural representation of the fixed cell of embodiment 2.
The specific embodiment
Below in conjunction with accompanying drawing this utility model is specified, those skilled in the art are to be understood that device size described in the utility model is not limited to following embodiment, can adjust according to practical situation, but all in the scope of this utility model protection:
1 one kinds of devices that are used for the mammary gland three-dimensional imaging of embodiment
The structure of present embodiment is shown in Fig. 1-4, and the name of each element is called: 1. circular gear, 2. arc ultrasonic array, 3. bowl-shape arc shell, 4. ultrasonic coupling liquid, 5. protecting film, 6. electromagnetic horn, 7. waveguide, 8. microwave generator, 9. elastic seal ring, 10. frequency divider, 11. data acquisition circuits, 12. pre-process circuits, 13. motors, 14. drivers, 15. digital I/O cards, 16. computers, 17. display.
Wherein microwave generator 10 is selected the BW-1200HPT of China Arms Industry second 06 institute for use, but tranmitting frequency is the pulse microwave of 1.2GHz, pulsewidth be 0.5 or 1us optional; Data acquisition circuit 11 is the high-speed digitization instrument PCI-5105 (NI, the U.S.) of 8 passage synchronized sampling passages; Arc ultrasonic array 2 is the medical energy converter product based on the 1-3 composite of the up-to-date release of Guangzhou Doppler Electronics Technology Co., Ltd..
Present embodiment comprises that heat sound excites and sensing unit signal controlling and processing unit.
Heat sound excite with sensing unit by circular gear 1, arc ultrasonic array 2, in the bowl-shape arc shell 3, protecting film 5, electromagnetic horn 6, waveguide 7, microwave generator 8 of ultrasonic coupling liquid 4 is housed and circular elastic seal ring 9 is formed.Arc shell 3 both ends opens, its top diameter are 30cm, and base diameter is 5cm.Circular gear 1 location is installed in the top exterior walls of arc shell 3 with one heart, and the number of teeth of circular gear 1 processing is 48, and adopting motor 13 drives to finish a circular scanning needs 48 pulses at least.Circular elastic seal ring 9 combines with the top inner wall sealing of bowl-shape arc shell 3.The sidewall of bowl-shape arc shell 3 inlays two radians from the top to the bottom and arc shell 3 is complementary, angle is the arc ultrasonic array 2 of 90 degree.Each arc ultrasonic array 2 contains 128 array elements, and the seam at quarter between the array element is wide to be 0.03mm, and its mid frequency is 2.5MHz, and relative bandwidth is 75%, and area is 100mm * 10mm * 0.8mm.Protecting film 5 combines with the bottom sealing of bowl-shape arc shell 3.Ultrasonic coupling liquid 4 is housed in the arc shell 3.Electromagnetic horn 6 is positioned at protecting film 5 belows, and waveguide 7 one ends are connected with electromagnetic horn 6 bottoms, and the other end is connected with microwave generator 8.The upper edge of bowl-shape arc shell 3 lower edges and electromagnetic horn 6 is rotationally connected.
Signal controlling and processing unit are made up of frequency divider 10, data acquisition circuit 11, pre-process circuit 12, motor 13, driver 14, digital I/O card 15, computer 16 and display 17.
Described circular gear 1 is connected with a joggle with motor 13.Described computer 16, digital I/O card 15, driver 14 are connected with motor 13 lead successively.Described digital I/O card 15 also is connected with pre-process circuit 12, arc ultrasonic array 2 lead successively.Described data acquisition circuit 11 is connected with frequency divider 10, pre-process circuit 12 and computer 16 leads respectively.Described computer 16 also is connected with display 17 leads.Described frequency divider 10 is connected with described microwave generator 8 leads.
Present embodiment is applicable to the heat sound three-dimensional imaging of one-sided mammary gland, and the concrete operations step is:
1) tested mammary gland enters and is immersed in the ultrasonic coupling liquid 4 by the upper end open of arc shell 3, opens described device;
2) microwave generator 8 excites the pulse microwave that produces 1.2GHz to be coupled into waveguide 7, sees through protecting film 5 radiation through electromagnetic horn 6 and inspire hot acoustical signal on tested mammary gland, and the while is through the pulse microwave trigger data acquisition circuit 11 of frequency divider 10 frequency divisions; Arc ultrasonic array 2 receives hot acoustical signal and is converted into the signal of telecommunication and through behind the pre-process circuit 12, gathers computer 16 by data acquisition circuit 11;
3) gathered once hot acoustical signal after, computer 16 sends digital signal to driver 14 by digital I/O card 15, drive stepping motor 13 realizes stepping rotation, drives arc ultrasonic array 2 by circular gear 1 simultaneously and turns to next position around tested mammary gland;
4) repeating step 2 and 3;
5) after rotation sweep receives the hot acoustical signal in abundant orientation, computer 16 reconstructs the three-dimensional hot acoustic image of tested mammary gland by calculating, is shown in real time or processing such as follow-up printing by display 17.
2 one kinds of devices that are used for the bilateral breast three-dimensional imaging of embodiment
The structure of present embodiment is similar to embodiment 1, and difference is:
1) also comprises the fixed cell that mainly constitutes by workbench 18.Two manholes 19 that the center of circle is coaxial are arranged on the workbench 18, are that a described heat sound excites and sensing unit under each described manhole 19, each heat sound excite with sensing unit in circular gear 1 all be rotationally connected with workbench 18.
2) motor 13 simultaneously with two heat sound excite with sensing unit in circular gear 1 be connected with a joggle.
3) frequency divider 10 excites with the lead of microwave generator 8 in the sensing unit with two heat sound simultaneously and is connected.
4) each heat sound excite with sensing unit in, the arc ultrasonic array 2 that radian and bowl-shape arc shell 3 are complementary is inlayed the sidewall that is fixed on arc shell; Described arc ultrasonic array 2 contains 512 array elements, and the seam at quarter between the array element is wide to be 0.03mm, and its mid frequency is 2.5MHz, and relative bandwidth is 75%, and area is 100mm * 10mm * 0.8mm.
The operating procedure of this device is identical with embodiment 1 described step, and two bowl-shape arc shells rotate synchronously.
3 one kinds of devices that are used for the bilateral breast three-dimensional imaging of embodiment
The structure of present embodiment is similar to embodiment 2, and difference is:
Each heat sound excite with sensing unit in circular gear 1 be connected with a joggle with a motor 13 respectively.Two motors are connected with driver 14 leads simultaneously.The sidewall of each bowl-shape arc shell 3 is inlayed and is fixed the arc ultrasonic array 2 that two angles are 90 degree, each described arc ultrasonic array 2 contains 256 array elements, seam at quarter between the array element is wide to be 0.03mm, its mid frequency is 2.5MHz, relative bandwidth is 75%, and area is 80mm * 10mm * 0.8mm.
The operating procedure of this device is identical with embodiment 1 described step, and two bowl-shape arc shells can independent rotation, then can more scan the mammary gland that has pathological changes to suspect.
4 one kinds of devices that are used for the three-dimensional imaging of cranium brain of embodiment
The structure of present embodiment is similar to embodiment 1, and difference is:
Heat sound excite with sensing unit in, the diameter of bowl-shape arc shell is 70cm, arc ultrasonic array 2 circumference that three radians and bowl-shape arc shell 3 are complementary are fixed on the outer wall of arc shell symmetrically; Described arc ultrasonic array 2 contains 256 array elements, and the seam at quarter between the array element is wide to be 0.03mm, and its mid frequency is 3.5MHz, and relative bandwidth is 75%, and area is 80mm * 10mm * 0.8mm.
The operating procedure of this device is identical with embodiment 1 described step.
Claims (10)
1. a device that is used for biological tissue's three-dimensional imaging is characterized in that comprising that heat sound excites and sensing unit signal controlling and processing unit;
Described heat sound excite with sensing unit comprise circular gear (1), one or more arc ultrasonic array (2), in bowl-shape arc shell (3), protecting film (5), electromagnetic horn (6), waveguide (7) and the microwave generator (8) of ultrasonic coupling liquid (4) are housed; The top exterior walls location of described bowl-shape arc shell (3) is installed described circular gear (1) with one heart, the sidewall of bowl-shape arc shell (3) is inlayed the described arc ultrasonic array (2) that radian and bowl-shape arc shell (3) are complementary from the top to the bottom, the bottom of bowl-shape arc shell (3) combines with described protecting film (5) sealing; Described electromagnetic horn (6) is equipped with in the below of protecting film (5), and described waveguide (7) one ends are connected with electromagnetic horn (6) bottom, the other end is connected with described microwave generator (8); The upper edge of the lower edge of bowl-shape arc shell (3) and electromagnetic horn (6) is rotationally connected; Described signal controlling and processing unit are made up of frequency divider (10), data acquisition circuit (11), pre-process circuit (12), motor (13), driver (14), digital I/O card (15), computer (16) and display (17);
Described circular gear (1) is connected with a joggle with motor (13); Described computer (16), digital I/O card (15), driver (14) are connected with motor (13) lead successively, described digital I/O card (15) also is connected with pre-process circuit (12), arc ultrasonic array (2) lead successively, described data acquisition circuit (11) is connected with frequency divider (10), pre-process circuit (12) and computer (16) lead respectively, described computer (16) also is connected with display (17) lead, and described frequency divider (10) is connected with described microwave generator (8) lead.
2. device according to claim 1 is characterized in that: the sidewall of described bowl-shape arc shell (3) is inlayed a described arc ultrasonic array (2) from the top to the bottom.
3. device according to claim 1 is characterized in that: the sidewall of described bowl-shape arc shell (3) is inlayed two described arc ultrasonic array (2) from the top to the bottom.
4. device according to claim 3 is characterized in that: the angle of described two arc ultrasonic array (2) is 90 degree.
5. device according to claim 1 is characterized in that: the sidewall of described bowl-shape arc shell (3) is inlayed three or three the above arc ultrasonic array (2) from the top to the bottom.
6. according to the arbitrary described device of claim 1 to 5, it is characterized in that: described heat sound sensing unit comprises that also one seals bonded circular elastic seal ring (9) with bowl-shape arc shell (3) top inner wall.
7. device according to claim 6 is characterized in that: described device comprises that a described heat sound excites and sensing unit and described signal controlling and processing unit.
8. device according to claim 7, it is characterized in that: also comprise the fixed cell that mainly constitutes by workbench (18), a manhole (19) is arranged on the described workbench (18), be that described heat sound excites and sensing unit under the described manhole (19), described circular gear (1) is rotationally connected with workbench (18).
9. device according to claim 6 is characterized in that: described device comprises that two described heat sound excite and sensing unit and described signal controlling and processing unit; Frequency divider (10) in described signal controlling and the processing unit simultaneously and two heat excite with microwave generator (8) lead in the sensing unit and be connected; Motor in signal controlling and the processing unit (13) simultaneously and two heat excite with sensing unit in circular gear (1) be connected with a joggle, perhaps two described circular gears (1) are connected with a joggle with two motors (13) respectively, and two described motors (13) are connected with described driver (14) lead simultaneously.
10. device according to claim 9, it is characterized in that: also comprise the fixed cell that mainly constitutes by workbench (18), two manholes (19) that the center of circle is coaxial are arranged on the described workbench (18), be that a described heat sound excites and sensing unit under each described manhole (19), described circular gear (1) is rotationally connected with workbench (18).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 201020146903 CN201624674U (en) | 2010-04-01 | 2010-04-01 | 3D imaging device for biological tissue |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 201020146903 CN201624674U (en) | 2010-04-01 | 2010-04-01 | 3D imaging device for biological tissue |
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| CN201624674U true CN201624674U (en) | 2010-11-10 |
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| CN 201020146903 Expired - Fee Related CN201624674U (en) | 2010-04-01 | 2010-04-01 | 3D imaging device for biological tissue |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101816572A (en) * | 2010-04-01 | 2010-09-01 | 江西科技师范学院 | Early-stage breast cancer nondestructive screening and imaging system |
| CN103006273A (en) * | 2013-01-23 | 2013-04-03 | 上海海事大学 | Portable ultrasonic three-dimensional measuring device for soft tissues |
| CN106377278A (en) * | 2015-07-28 | 2017-02-08 | 中慧医学成像有限公司 | 3D imaging ultrasonic scanning method |
-
2010
- 2010-04-01 CN CN 201020146903 patent/CN201624674U/en not_active Expired - Fee Related
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101816572A (en) * | 2010-04-01 | 2010-09-01 | 江西科技师范学院 | Early-stage breast cancer nondestructive screening and imaging system |
| CN101816572B (en) * | 2010-04-01 | 2013-04-10 | 江西科技师范学院 | Early-stage breast cancer nondestructive screening and imaging system |
| CN103006273A (en) * | 2013-01-23 | 2013-04-03 | 上海海事大学 | Portable ultrasonic three-dimensional measuring device for soft tissues |
| CN106377278A (en) * | 2015-07-28 | 2017-02-08 | 中慧医学成像有限公司 | 3D imaging ultrasonic scanning method |
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Granted publication date: 20101110 Termination date: 20110401 |