CN201571444U - Special tissue cryopreservation tube for HER2 detection of breast cancer - Google Patents

Special tissue cryopreservation tube for HER2 detection of breast cancer Download PDF

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Publication number
CN201571444U
CN201571444U CN2009202452648U CN200920245264U CN201571444U CN 201571444 U CN201571444 U CN 201571444U CN 2009202452648 U CN2009202452648 U CN 2009202452648U CN 200920245264 U CN200920245264 U CN 200920245264U CN 201571444 U CN201571444 U CN 201571444U
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CN
China
Prior art keywords
breast cancer
her2
casing
tube
shell
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CN2009202452648U
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Chinese (zh)
Inventor
李南林
薛妍
李烦繁
董文鹏
田梦
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Fourth Military Medical University FMMU
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Fourth Military Medical University FMMU
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Priority to CN2009202452648U priority Critical patent/CN201571444U/en
Application granted granted Critical
Publication of CN201571444U publication Critical patent/CN201571444U/en
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Abstract

The utility model discloses a special tissue cryopreservation tube for HER2 detection of breast cancer. The tissue cryopreservation tube comprises a casing filled with formaldehyde stationary liquid containing 4 percent of neutral phosphoric acid buffer; the casing is provided with a tube cap; a fixing strap is arranged at one end of the opening of the casing, and a retainer ring is fixed at the other end of the opening of the casing; the tube cap is fixed at the opening of the casing through the fixing strap; and the end part of the fixing strap penetrates through the retainer ring to fix the tube cap. In the special specimen fixation tube for HER2 detection of breast cancer provided by the utility model, a standard special tissue cryopreservation tube is made from the formaldehyde stationary liquid containing 4 percent of neutral phosphoric acid buffer, so that tumor specimen tissues obtained by surgical excision as well as needle biopsy can be put in the special tissue cryopreservation tube directly, and the problem that HER2 specimen tissue fixation fluid is lack of standardization is solved; and the utility model overcomes the anthropic factor resulting in the low positive rate of HER2 detection to the utmost extent.

Description

A kind of frozen pipe of private organizations that is used for breast cancer HER2 detection
Technical field
The utility model relates to medical detection technique field, relates to a kind of kit that is used for fixing clinical puncture and specimens from pri, and particularly a kind of breast cancer HER2 that is used for detects the frozen pipe of private organizations.
Background technology
Breast cancer is one of modal malignant tumour of women.According to statistics, the incidence of disease accounts for the 7-10% of the various malignant tumours of whole body.Its morbidity is normal relevant with heredity, between 40-60 year, the women's incidence of disease before and after climacteric is higher, is one of a kind of women's of having a strong impact on physical and mental health even life-threatening common cancer.Male breast carcinoma is rare.There is patient with breast cancer 200,000 in China the beginning of the nineties in last century, and annual new cases about 50,000.
The present clinical samples of breast cancer source is two kinds of possibilities nothing but: the one, and excision, the 2nd, aspiration biopsy.The former is in the great majority.The fixedly requirement of sample is no more than 1h from the regular time of drawing materials.Set time is advisable with 6-48h, and should not be with the quick fixing organization of microwave.But domestic most of hospital all is difficult to accomplish standardization.Especially the cardinal principle sample of excision after performing the operation, the tumour enclosed mass is embedded in the breast tissue, formaldehyde fixed liquid must first infiltrate skin histology, adipose tissue and fine and close breast tissue could arrive tumor tissues, reaches fixing to such an extent as to be difficult in time of requirement, causes organizing autolyze.
For example:
1, known HER2 has the amplification of gene and the overexpression of albumen in 25%~30% primary breast IDC, but the breast cancer patient FISH of applicant place hospital detects HER2 positive patients less than 10%.There is this error result, can brings immeasurable difficulty, to such an extent as to a lot of patient has lost the treatment that obtain patient's diagnosis and treatment.
2, the sample fixation of tissue liquid of standard detection regulation HER2 is 4% neutrality (phosphoric acid buffer) formaldehyde fixed liquid.But most of hospitals all can not carry out by standard code, and the positive rate that HER2 is detected is on the low side.
Therefore, sample fixation of tissue liquid is made easy easy-to-use kit great clinical meaning will be arranged.
Summary of the invention
The purpose of this utility model is, provides a kind of breast cancer HER2 that is used for to detect the frozen pipe of private organizations, with directly pouring into 4% neutrality (phosphoric acid buffer) formaldehyde fixed liquid in the cell cryopreservation pipe, makes disposable finished product with standby.
In order to realize above-mentioned task, the utility model is taked following technical solution:
A kind of breast cancer HER2 that is used for detects the frozen pipe of private organizations, comprise the shell that the formaldehyde fixed liquid that contains 4% neutral phosphoric acid buffer is housed, shell disposes the pipe lid, it is characterized in that, oral area one end of described shell is provided with fixed band, the oral area other end of shell has retainer ring, and pipe lid is fixed on the oral area of shell by fixed band, and the end of fixed band is passed retainer ring and will manage lid and fix.
Other characteristics of the present utility model are: described shell, pipe lid and the integrated making of fixed band.
Also indicate scale on the described shell.
The breast cancer HER2 that is used for of the present utility model detects special-purpose sample stationary pipes, 4% neutrality (phosphoric acid buffer) formaldehyde fixed liquid is made the frozen pipe of detection private organizations of standard, no matter excision still is the tumor specimen tissue of aspiration biopsy, can directly put into the frozen pipe of private organizations, solved the nonstandard problem of sample fixation of tissue liquid of HER2, on to greatest extent, solved HER2 and detected positive rate human factor on the low side.
Description of drawings
Fig. 1 is a structural representation of the present utility model;
Fig. 2 is the end view of Fig. 1.
The utility model is described in further detail below in conjunction with accompanying drawing.
Embodiment
Referring to accompanying drawing, the breast cancer HER2 that is used for of the present utility model detects the frozen pipe of private organizations, comprise and be filled with the shell 1 that contains 4% neutrality (phosphoric acid buffer) formaldehyde fixed liquid, shell 1 disposes pipe and covers 2, oral area one end at shell 1 is provided with fixed band 3, and this fixed band 3 covers 2 with pipe and is connected as a single entity, and the oral area other end of shell 1 has retainer ring 4, pipe cover 2 and is fixed on the oral area of shell 1 by fixed band 3, and the end of fixed band 3 is passed retainer ring 4 and will be managed and cover 2 and fix.
Shell 1, pipe cover 2 and fixed band 3 integrated making.Its material can be selected the plastics one-shot forming.
Also indicate scale on the shell 1, can be used for the can of 4% neutrality (phosphoric acid buffer) formaldehyde fixed liquid easily.
Certainly, shell 1 can also be selected other material.
During use, from retainer ring 4 fixed band 3 is pulled out, open the pipe lid 2 on the shell 1, tumor specimen tissue with fixing operation excision or aspiration biopsy, place in the shell 1, pipe cover 2 and seals with shell 1 then, and fixed band 3 is inserted in the retainer ring 4, can detect according to the regulation of " breast cancer HER2 guide detection ", solved HER2 on to greatest extent and detected positive rate human factor on the low side.

Claims (3)

1. one kind is used for the frozen pipe of breast cancer HER2 detection private organizations, comprise shell (1), shell (1) disposes pipe lid (2), it is characterized in that, oral area one end of described shell (1) is provided with fixed band (3), the oral area other end of shell (1) has retainer ring (4), and pipe lid (2) is fixed in the oral area of shell (1) by fixed band (3), and the end of fixed band (3) is passed retainer ring (4) and will be managed lid (2) and fix.
2. the breast cancer HER2 that is used for as claimed in claim 1 detects the frozen pipe of private organizations, it is characterized in that described shell (1), pipe lid (2) and the integrated making of fixed band (3).
3. the breast cancer HER2 that is used for as claimed in claim 1 detects the frozen pipe of private organizations, it is characterized in that described shell also indicates scale on (1).
CN2009202452648U 2009-11-16 2009-11-16 Special tissue cryopreservation tube for HER2 detection of breast cancer Expired - Fee Related CN201571444U (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN2009202452648U CN201571444U (en) 2009-11-16 2009-11-16 Special tissue cryopreservation tube for HER2 detection of breast cancer

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN2009202452648U CN201571444U (en) 2009-11-16 2009-11-16 Special tissue cryopreservation tube for HER2 detection of breast cancer

Publications (1)

Publication Number Publication Date
CN201571444U true CN201571444U (en) 2010-09-08

Family

ID=42691326

Family Applications (1)

Application Number Title Priority Date Filing Date
CN2009202452648U Expired - Fee Related CN201571444U (en) 2009-11-16 2009-11-16 Special tissue cryopreservation tube for HER2 detection of breast cancer

Country Status (1)

Country Link
CN (1) CN201571444U (en)

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Legal Events

Date Code Title Description
C14 Grant of patent or utility model
GR01 Patent grant
CF01 Termination of patent right due to non-payment of annual fee

Granted publication date: 20100908

Termination date: 20161116

CF01 Termination of patent right due to non-payment of annual fee