CN201551415U - Degradable vena cava filter - Google Patents
Degradable vena cava filter Download PDFInfo
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- CN201551415U CN201551415U CN 200920352383 CN200920352383U CN201551415U CN 201551415 U CN201551415 U CN 201551415U CN 200920352383 CN200920352383 CN 200920352383 CN 200920352383 U CN200920352383 U CN 200920352383U CN 201551415 U CN201551415 U CN 201551415U
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- band
- vena cava
- filter
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Abstract
The utility model discloses a degradable vena cava filter, which comprises a bracket body and a filter, wherein the bracket body takes the shape of a circular cylinder fixedly formed in a latch manner after at least two strips connected through a connector are curled; and the filter comprises four filtration wires and weaving wires for connecting the filtration wires in the circular direction, wherein one end of the filter is fixed on the circular ring formed by curling any one strip of the bracket body, while the other end thereof is rounded up and fixed together. The filter has a simple structure, can be easily implanted in the vena cava of human body and placed stably in the vena cava, and is less susceptible to stab blood vessels, so that the phenomenon that the pulmonary embolism is caused and degraded gradually in the human body can be prevented, and a series of problems caused by the permanent bracket which is placed in the human body for life can be avoided.
Description
Technical field
This utility model relates to a kind of vena cava filter, is specifically related to a kind of degradable vena cava filter.
Background technology
Vena cava filter be mainly used in the treatment pulmonary embolism (be called for short pulmonary infarction, pulmonary embolism, PE).PE is a kind of common disease, and the 3rd of its sickness rate intentions angiopathy is only second to hypertension and coronary heart disease.PE be since around the thrombosis of deep venous thrombosis or right cardiac cavity come off and enter pulmonary circulation, stop up pulmonary artery or its branch, and then a series of clinical pathology physiological changes that cause based on the pulmonary circulatory function obstacle.Result of study shows, causes the thrombosis that embolus that PE takes place mainly comes off from limb deep vein or pelvic cavity vein, accounts for 60～90% of embolus source.Thrombosis comes off and gets back to heart along the caval vein system, finally causes pulmonary embolism.The generation of PE can't predict initiatively that usually in case after experience takes place first, no matter whether treat, about 20～60% patient can be recurred.For mortality PE, rescue time is very limited, and nearly 10% patient is dead in 1 hour.The treatment of PE comprises Drug therapy and operative treatment, and the effective measures of control PE are its generations of prevention, and to enter pulmonary artery be direct, the most effective precautionary approach to embolus and come off with the prevention of surgical intervention means.The vena cava filter of clinical practice first in 1967 not only can be controlled thrombosis effectively and enter pulmonary artery, and can not form tangible caval vein obstruction.Constantly Wicresoft's implanted prosthetics of development also makes vena cava filter implant becomes the most effective means of prevention PE of generally acknowledging at present.
At present, the vena cava filter of Ying Yonging generally is to adopt Ni-Ti (Ni-Ti) marmem clinically, utilizes tinsel basketry or microtubule laser engraving technology, is made into the self-expansion type filter, its shape utilizes conduit to carry the implant cavity vein as a umbrella that struts or Bird's Nest.According to the filter length of retention time in vivo, vena cava filter can be divided into permanent filter and provisional filter.
Permanent filter is used more, and it is implanted retrocaval and is fixed in blood vessel wall and follows the patient lifelong, but this filter retains in vivo for a long time as foreign body, may be shifted, severe complications such as caval vein perforation, local thrombus formation, postcava obstruction; Give many patients because of using permanent filter to take the anticoagulant medicine for a long time even throughout one's life, especially young patient is brought inconvenience.Provisional filter can take out in body in the regular hour, thereby avoided implanting the problem that permanent filter brings, but in actual applications owing to reasons such as tissue adhesion, parcels, provisional filter possibly can't reclaim smoothly, as reclaiming complication such as may cause that caval vein is torn by force; The recovery of filter also increases patient's wound and financial burden.
It is generally acknowledged that the treatment cycle of acute thrombus embolism class diseases is 3～6 months.If adopt degradation material to produce degradable vena cava filter, in the suitable time, in human body, degrade after making its performance curative effect, just may solve the problem that above permanent or provisional filter occurs in using.
At present, the application clinically of degradable biomedical material increases gradually.Compare with general metal implant material, degradation material has mechanical strength within a certain period of time, and degraded is gradually finally got rid of external by body metabolism afterwards.Polylactide (Polylactide is called for short PLA), poly-Acetic acid, hydroxy-, bimol. cyclic ester (Polyglycolide is called for short PGA), and copolymer p LGA, be the high molecular polymer that drugs approved by FDA is used for implant into body, be mainly used to make orthopaedics implant, as nail, hone lamella and spinal fusion device.PLA is a chiral molecule, and the polymer of four kinds of different shapes is arranged, i.e. PLLA, PDLA, PD, LLA and meso-PLA.Wherein to be half hitch crystalline for PLLA, and the mechanical property of material is better.PLLA is degradable macromolecular material, and its degradation time is 3～12 months, and catabolite is a lactic acid, and finally metabolism is carbon dioxide and water, excretes.
Magnesium alloy is the present more a kind of degradable metal material of making intravascular stent of research, and the report of zoopery and clinical research has been arranged at present, is expected to obtain in recent years the FDA approval.Magnesium alloy corrodes degraded in vivo, generates magnesium hydroxide, magnesium chloride, and discharges a certain amount of hydrogen.Owing to contain magnesium elements in the human body, so can not cause toxic reaction during the magnesium alloy degraded.
The utility model content
The technical problems to be solved in the utility model provides a kind of degradable vena cava filter, form by stake body and filtering bodies, wherein said stake body can be with described filtering bodies safety, be fixed in the position of determining in the blood vessel reposefully, described filtering bodies can effectively prevent the thrombosis that comes off and enter pulmonary artery, this vena cava filter can realize preventing the function of pulmonary embolism generation with simple structure, this filter is easy to the implant into body caval vein and steadily lays therein and be difficult for stabbing blood vessel, because of this filter is made by degradation material, can in human body, degrade fully after finishing its treatment mission, can avoid using some problems permanent or that provisional filter brought that have now.
For solving the problems of the technologies described above, this utility model adopts following technical proposals:
A kind of degradable vena cava filter is made up of stake body and filtering bodies;
Described stake body is connected by connector by at least 2 bands, fix by the fore shaft that lays respectively at the band two ends with the mutual snap close of latch that fore shaft is complementary behind the described band circumflexion, form the cylindrical shape intravascular stent, wherein the bar end that has latch one end is positioned at rack tube;
Described filtering bodies is formed by at least 4 filter wire with the braided wires that described filter wire hoop links together, wherein said filtering bodies one end is fixed on behind any ribbon curling of described stake body on the formed annulus, the described filtering bodies other end gather and fixing (as modes such as bonding or bindings) together;
Described filtering bodies one end can by filter wire terminal fixing (as modes such as bonding or bindings) as described in behind any ribbon curling of stake body on the formed annulus, between wherein every adjacent two filter wire at interval evenly;
Band one end in the described stake body has at least 1 fore shaft, the band other end has half a blunt nosed arrow-shaped end, this end one side is that a zigzag latch and crown have fore shaft one extreme direction towards bar, band one side is adjacent with described zigzag latch to have at least 2 reversed acanthoid latches and crown towards described zigzag latch, and the band opposite side is a linear structure;
Also have a kind of being chosen as, band one end in the described stake body has at least 1 fore shaft, the band other end has a blunt nosed arrow-shaped end, these end both sides are that a pair of zigzag latch and crown have fore shaft one extreme direction towards bar, and the band both sides are adjacent with described zigzag latch at least 2 pairs of reversed acanthoid latches and the crown zigzag latch towards homonymy; Also can on the basis of this selection, further be chosen to be, band one end in the described stake body has at least 2 fore shafts, be provided with the short otch of this adjacent fore shaft of perforation between the wherein adjacent fore shaft, in the middle of the band of the band other end from described zigzag latch to position between this zigzag latch reversed acanthoid latch root farthest a long otch is arranged, described length or short otch help reducing when this band bends to tubulose its outside tension force;
At least 2 connectors are arranged between the adjacent ribbons in the described stake body, and connector is between the fore shaft place or fore shaft and reversed acanthoid latch at band of band;
That fore shaft in the described stake body on the band is shaped as is square, rectangle, " U " shape or " mountain " font etc.;
Described stake body length and external diameter can determine that wall thickness can be 0.3～0.5mm according to the clinical practice needs;
The filtering bodies vertebral height of described similar cone can be determined according to the clinical practice needs, the circular cross-section of vertebral body rounded bottom surface and described cylinder-shaped bracket body is complementary, the filter wire of described filtering bodies and/or braided wires can be the cylinder silk of diameter 0.1～2.0mm, or are the silk ribbon of cross-sectional length 0.1～5.0mm, section thickness 0.1～2.0mm;
The manufactured materials of described stake body is macromolecular material PLA, PGA or PLGA, and the manufactured materials of described filtering bodies is macromolecular material PLA, PGA or PLGA, or magnesium alloy materials AE21 or WE43.
Before adopting balloon expanding technology to insert, the bar of the stake body of described vena cava filter is had latch one end to be penetrated in the fore shaft, snap close makes the intravital strip portion of cylinder-shaped bracket curling overlapping in from a nearest reversed acanthoid latch place of fore shaft, thereby reaches the snap close state of its diameter minimum; Or determine to implant the suitable diameter of fore-stock body and snap close as the case may be in suitable latch position; After inserting in the blood vessel with balloon expanding technology, through inflation pressure make fore shaft slip over that reversed acanthoid latch rear catch is fixed in that bar has the zigzag latch of latch one end end and the reversed acanthoid latch that is adjacent between (as Fig. 1), stake body is fixed on the blood vessel wall.But when sacculus shrank, the agnail on the band was stuck on its corresponding fore shaft, and support can not be bounced back.The degradation time of this vena cava filter is 3～6 months, by material composition and its degradation time of microstructure scalable that changes its stake body and filtering bodies.
Experiment shows, the structural design of this stake body helps carrying out dwindling when sacculus is carried its diameter, the stake body that agnail structure on the band not only is beneficial to this vena cava filter is sent in definite blood vessel and opens behind the position again, also can prevent support opened by balloon expandable after retraction again, this stake body has radial support power preferably and uses required mechanical mechanics property as intravascular stent; Described filtering bodies can be fixed in ad-hoc location in the blood vessel safely and steadly because of being combined on this stake body, realize that it prevents the function that pulmonary embolism takes place.
According to above scheme, can make macromolecular material silk or band with extrusion by melting or cutter patterning method, or, utilize mould to work out the filtering bodies structure again with extruding or drawing process is made into Mg alloy wire; In addition, the useable solvents volatility process is made thin film with macromolecular material, and reuse laser engraving technology cuts out interconnective a plurality of band from this thin film, produces polycyclic degradable stake body; Then, with the binding of the filament of filtering bodies opening one end or adhere on certain annulus of stake body, form a complete vena cava filter (as Fig. 1), by material composition and its degradation time of microstructure scalable that changes this filter.
The beneficial effects of the utility model are: this degradable vena cava filter is simple in structure, be easy to the implant into body caval vein and steadily lay therein and be difficult for stabbing blood vessel, can catch generation and finish its medical functions after in body in the gradually degraded of thrombosis to prevent pulmonary infarction.Use this degradable vena cava filter, both some problems that can avoid permanent filter to be brought because of existing in the human body all the life also needn't will be done second operation and take out filter as using provisional filter.
Description of drawings
Below in conjunction with accompanying drawing enforcement of the present utility model is described in further detail.
Fig. 1 is the perspective view of the vena cava filter of this utility model embodiment 1.
Fig. 2 is the deployed configuration sketch map of the stake body of this utility model embodiment 1.
Fig. 3 is the deployed configuration sketch map of the stake body of this utility model embodiment 2.
Fig. 4 is the deployed configuration sketch map of the stake body of this utility model embodiment 3.
The specific embodiment
The following examples can illustrate in greater detail this utility model, but do not limit this utility model in any form.
Embodiment 1
A kind of degradable vena cava filter of this utility model (as Fig. 1) is made up of stake body (1) and filtering bodies (2).Described filtering bodies (2) is formed by 4 filter wire (21) with the braided wires (22) that described filter wire (21) hoop links together, wherein said filtering bodies (2) one ends can be bonded on the formed annulus in the curling back of a band (11) of described stake body (1) outer rim by filter wire (21) end, even at interval between every adjacent two filter wire (21), described filtering bodies (2) other end is gathered and is bonded together, described filtering bodies (2) is the network structure of similar cone, can make diameter with extrusion by melting earlier is the PLA macromolecular material silk of 0.4mm, utilizes mould establishment filtering bodies (2) again; Described stake body (1) is a cylindrical shape, is fixed with the form of snap close and is formed by interconnective band (11) back of curling;
Fig. 2 is the structural representation after above-mentioned stake body (1) launches in the present embodiment, described stake body (1) is connected by the fore shaft place of 1 connector (12) at band (11) with adjacent ribbons (11) each other by 4 bands (11), fix by the fore shaft (111) that lays respectively at band (11) two ends with the mutual snap close of latch that fore shaft (111) is complementary behind described band (11) circumflexion, form the cylindrical shape intravascular stent, wherein band (11) has the end of latch one end to be positioned at rack tube;
Band (11) one ends in the described support have 1 " mountain " font fore shaft (111), the opening that wherein is somebody's turn to do " mountain " word has latch one end towards band (11), band (1) other end has a blunt nosed arrow-shaped end, these end both sides are that a pair of zigzag latch (113) and crown have fore shaft one extreme direction towards band (1), and band (1) both sides are adjacent with described zigzag latch (13) 2 pairs of reversed acanthoid latches (112) and the crown zigzag latch (113) towards homonymy;
Described support is long to be 20.0mm, and external diameter is 5.0mm, and wall thickness is 0.3mm, and its manufactured materials is a macromolecular material PLA thin film.
Can with solvent evaporation method macromolecular material PLA be made thin film earlier, reuse laser engraving technology cuts out above-mentioned interconnective 4 bands (11) from this thin film, and the crooked back of band (11) is fixing by fore shaft (111), forms stake body (1); At last, filter wire (21) end of the above-mentioned filtering bodies for preparing (2) opening one end is adhered on the annulus that stake body (1) the one end band (11) made forms, become a complete vena cava filter.
Embodiment 2
A kind of degradable vena cava filter of this utility model is made up of stake body (1) and filtering bodies (2).Described filtering bodies (2) is formed by 5 filter wire (21) with the braided wires (22) that described filter wire (21) hoop links together, wherein said filtering bodies (2) one ends can be bonded on the formed annulus in the curling back of any band (11) of described stake body (1) by the filter wire end, even at interval between every adjacent two filter wire (21), described filtering bodies (2) other end is gathered and is bonded together, described filtering bodies (2) is the network structure of similar cone, the PGA thin film that can earlier solvent evaporation method be made is made cross-sectional length 1.0mm with the cutter patterning method, the silk ribbon of section thickness 0.6mm utilizes mould to work out this filtering bodies (2) again; Described stake body (1) is a cylindrical shape, is fixed with the form of snap close and is formed by interconnective band (11) back of curling;
Fig. 3 is the structural representation after above-mentioned stake body (1) launches in the present embodiment, described stake body (1) is connected by the fore shaft place of 2 connectors (12) at band (11) with adjacent ribbons (11) each other by 6 bands (11), fix by the fore shaft (111) that lays respectively at band (11) two ends with the mutual snap close of latch that fore shaft (111) is complementary behind described band (11) circumflexion, form the cylindrical shape intravascular stent, wherein band (11) has the end of latch one end to be positioned at rack tube;
Band (11) one ends in the described support have 2 square fore shafts (111), be provided with a short otch (115) that connects this adjacent fore shaft between the wherein adjacent fore shaft, band (11) other end has a blunt nosed arrow-shaped end, these end both sides are that a pair of zigzag latch (113) and crown have fore shaft one extreme direction towards band (11), band (11) both sides are adjacent with described zigzag latch (113) to have 2 pairs of reversed acanthoid latches (112) and crown towards the zigzag latch (113) of homonymy, is provided with a long otch (114) in the middle of the band (11) from described zigzag latch (113) to position between this zigzag latch (13) reversed acanthoid latch (112) root farthest;
Described support is long to be 40.0mm, and external diameter is 15.0mm, and wall thickness is 0.5mm, and its manufactured materials is a macromolecular material PGA thin film.
The useable solvents volatility process is made thin film with macromolecular material PGA, and reuse laser engraving technology cuts out above-mentioned interconnective 6 bands (11) from this thin film, and the crooked back of band (11) is fixing by fore shaft (111), forms stake body (1); At last, filter wire (21) end of the above-mentioned filtering bodies for preparing (2) opening one end is adhered on the annulus that stake body (1) the one end band (11) made forms, become a complete vena cava filter.
Embodiment 3
A kind of degradable vena cava filter of this utility model is made up of stake body (1) and filtering bodies (2).Described filtering bodies (2) is formed by 6 filter wire (21) with the braided wires (22) that described filter wire (21) hoop links together, wherein said filtering bodies (2) one ends can be bonded on the formed annulus in the curling back of any band (11) of described stake body (1) by the filter wire end, even at interval between every adjacent two filter wire (21), described filtering bodies (2) other end is gathered and is bonded together, described filtering bodies (2) is the network structure of similar cone, can be earlier with extruding or drawing process is made into the AE21 Mg alloy wire that diameter is 0.2mm, utilize mould to work out this filtering bodies (2) again; Described stake body (1) is a cylindrical shape, is fixed with the form of snap close and is formed by interconnective band (11) back of curling;
Fig. 4 is the structural representation after above-mentioned stake body (1) launches in the present embodiment, described stake body (1) is connected at the fore shaft (111) of band (11) and the middle place between the reversed acanthoid latch (112) by 1 connector (12) with adjacent ribbons (11) each other by 5 bands (11), fix by the fore shaft (111) that lays respectively at band (11) two ends with the mutual snap close of latch that fore shaft (111) is complementary behind described band (11) circumflexion, form the cylindrical shape intravascular stent, wherein band (11) has the end of latch one end to be positioned at rack tube;
Band (11) one ends in the described support have 1 square fore shaft (111), band (1) other end has half a blunt nosed arrow-shaped end, this end one side is that a zigzag latch (113) and crown have fore shaft one extreme direction towards band (11), band (11) one sides are adjacent with described zigzag latch (113) to have 3 reversed acanthoid latches (12) and crown towards described zigzag latch (113), and band (11) opposite side is a linear structure;
Described support is long to be 30.0mm, and external diameter is 10.0mm, and wall thickness is 0.4mm, and its manufactured materials is a macromolecular material PLGA thin film.
The useable solvents volatility process is made thin film with macromolecular material PLGA, and reuse laser engraving technology cuts out above-mentioned interconnective 5 bands (11) from this thin film, and the crooked back of band (11) is fixing by fore shaft (111), forms stake body (1); At last, filter wire (21) end of the above-mentioned filtering bodies for preparing (2) opening one end is adhered on the annulus that stake body (1) the one end band (11) made forms, become a complete vena cava filter.
Obviously, the foregoing description of the present utility model only is for this utility model example clearly is described, and is not to be qualification to embodiment of the present utility model.For those of ordinary skill in the field, can also make other changes in different forms on the basis of the above description.Here can't give exhaustive to all embodiments.Everyly belong to the row that conspicuous variation that the technical solution of the utility model extends out or change still are in protection domain of the present utility model.
Claims (10)
1. a degradable vena cava filter is characterized in that: be made up of stake body (1) and filtering bodies (2);
Described stake body (1) is connected by connector (12) by at least 2 bands (11), fix by the fore shaft (111) that lays respectively at band (11) two ends with the mutual snap close of latch that fore shaft (111) is complementary behind described band (11) circumflexion, form the cylindrical shape intravascular stent, wherein band (11) has the end of latch one end to be positioned at rack tube;
Described filtering bodies (2) is formed by at least 4 filter wire (21) with the braided wires (22) that described filter wire (21) hoop links together, wherein said filtering bodies (2) one ends are fixed on the formed annulus in the curling back of any band (11) of described stake body (1), and described filtering bodies (2) other end is gathered and is fixed together.
2. a kind of degradable vena cava filter according to claim 1, it is characterized in that: described filtering bodies (2) one ends are fixed on the formed annulus in the curling back of any band (11) of described stake body (1) by filter wire (21) end, filter wire (21) end of described filtering bodies (2) other end is gathered and is fixed together, and is even at interval between wherein every adjacent two filter wire (21).
3. a kind of degradable vena cava filter according to claim 1, it is characterized in that: band (11) one ends in the described stake body (1) have at least 1 fore shaft (111), band (11) other end has half a blunt nosed arrow-shaped end, this end one side is that a zigzag latch (113) and crown have fore shaft one extreme direction towards band (11), band (11) one sides are adjacent with described zigzag latch (113) to have at least 2 reversed acanthoid latches (112) and crown towards described zigzag latch (113), and band (11) opposite side is a linear structure.
4. a kind of degradable vena cava filter according to claim 1, it is characterized in that: band (11) one ends in the described stake body (1) have at least 1 fore shaft (111), band (11) other end has a blunt nosed arrow-shaped end, these end both sides are that a pair of zigzag latch (113) and crown have fore shaft one extreme direction towards band (11), and band (11) both sides are adjacent with described zigzag latch (113) at least 2 pairs of reversed acanthoid latches (112) and the crown zigzag latch (113) towards homonymy.
5. a kind of degradable vena cava filter according to claim 4, it is characterized in that: band (11) one ends in the described stake body (1) have at least 2 fore shafts (111), in the middle of the short otch (115) that one this adjacent fore shaft of perforation is arranged between the wherein adjacent fore shaft, the band other end the band (11) a long otch (114) is arranged from described zigzag latch (113) to position between this zigzag latch (113) reversed acanthoid latch (112) root farthest.
6. according to claim 1,2,3,4 or 5 described a kind of degradable vena cava filters, it is characterized in that: between the adjacent ribbons (11) in the described stake body (1) at least 1 connector (12) is arranged, connector (12) is positioned at the fore shaft (111) of band (11) and locates or be positioned between the fore shaft (111) and reversed acanthoid latch (112) of band (11).
7. according to claim 1,2,3,4 or 5 described a kind of degradable vena cava filters, it is characterized in that: the fore shaft (111) in the described stake body (1) on the band (11) is shaped as square, rectangle, " U " shape or " mountain " font.
8. according to claim 1,2,3,4 or 5 described a kind of degradable vena cava filters, it is characterized in that: the manufactured materials of described stake body (1) is macromolecular material PLA, PGA or PLGA.
9. according to claim 1,2,3,4 or 5 described a kind of degradable vena cava filters, it is characterized in that: the manufactured materials of described filtering bodies (2) is macromolecular material PLA, PGA or PLGA, or magnesium alloy materials AE21 or WE43.
10. according to claim 1,2,3,4 or 5 described a kind of degradable vena cava filters, it is characterized in that: filter wire of described filtering bodies (21) and/or braided wires (22) are the cylinder silk of 0.1～2.0mm for diameter, or are the silk ribbon of cross-sectional length 0.1～5.0mm, section thickness 0.1～2.0mm.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 200920352383 CN201551415U (en) | 2009-12-24 | 2009-12-24 | Degradable vena cava filter |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 200920352383 CN201551415U (en) | 2009-12-24 | 2009-12-24 | Degradable vena cava filter |
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| CN201551415U true CN201551415U (en) | 2010-08-18 |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109963527A (en) * | 2016-12-16 | 2019-07-02 | 北京阿迈特医疗器械有限公司 | Biodegradable thrombus filter and preparation method thereof, purposes and conveying device |
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2009
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109963527A (en) * | 2016-12-16 | 2019-07-02 | 北京阿迈特医疗器械有限公司 | Biodegradable thrombus filter and preparation method thereof, purposes and conveying device |
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Granted publication date: 20100818 Termination date: 20101224 |