CN201481788U - Acupuncture needle - Google Patents

Acupuncture needle Download PDF

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CN201481788U
CN201481788U CN2009201605167U CN200920160516U CN201481788U CN 201481788 U CN201481788 U CN 201481788U CN 2009201605167 U CN2009201605167 U CN 2009201605167U CN 200920160516 U CN200920160516 U CN 200920160516U CN 201481788 U CN201481788 U CN 201481788U
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needle
heating wire
acupuncture
tumor
needle body
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唐大鸣
赵百孝
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Abstract

An acupuncture needle comprises a needle body, a needle point and a needle handle, wherein the needle point is arranged at the front end of the needle body; the needle body is a metal needle tube; a heating wire is placed in the needle tube of the needle body; the needle tube and the heating wire are provided with an insulation structure; the heating wire is connected with the needle point and the needle body to form a loop; and in the temperature of 20 DEG C, the resistivity of the heating wire at the needle body is smaller than 9.78 *10-8 (Omegam), and resistivity of the heating wire at the needle point is larger than 1*10-7 (Omegam).The acupuncture needle can perform functions of acupuncture, needle warming moxibustion and fire needling; after current is input, a heat sense flows deep into body and then transmits and spreads, as the current becomes heavier and heavier, the temperature becomes higher and higher, the acupuncture needle is just like a fire needle, has constant and adjustable temperature, and can lead thermal radiation deep into the body.

Description

A kind of acupuncture needle
Technical field
This utility model relates to a kind of Chinese medicine acupuncture pin, specifically, relates to the warm pin in a kind of Chinese medicine acupuncture pin, fiery pin.
Background technology
Acupuncture medicine is the important component part of Chinese medicine, its outstanding feature is exactly without endo-medicine, and only need stimulates the acupuncture points on the human body or the specific part of human body flesh table, by the propagated sensation and the effect of channel system, just can treat the inside and outside various diseases of human body the exterior and the interior.Acupuncture medicine is mixed together in different science and culture fields, and is of long standing and well established, goes through thousand and do not wane.Accepted by countries in the world at present, its therapeutic domain is wide, has no side effect, and welcome by the patient.
Acupuncture needle is the material base of acupuncture medicine development, is acupuncturist's instrument, and the development of acupuncture needle is exactly the epitome of acupuncture medicine development.Development high-quality, high-performance, easy and simple to handle, acupuncture needle that the cost low price is reasonable, evident in efficacy are the developing direction of acupuncture and moxibustion instrument and material.
" thorn of quenching " in motherland's medical science is fiery pin, is one of important method of acupuncture.Traditional fiery pin generally after thrusting body, the needle body natural cooling, temperature decreases, thereby is difficult to keep stationary temperature in vivo.The shortcoming of the maximum of warm pin of tradition and fiery pin is that complex operation is difficult for grasping.Can't quantize, be difficult for its treatment mechanism of further investigation, thereby, hindered its development and used widely.
The utility model content
A purpose of the present utility model is to provide a kind of acupuncture needle of only needle point heating.
A purpose of the present utility model is to provide a kind of only needle point heating and temperature can be controlled and quantized acupuncture needle.
For achieving the above object, the technical solution of the utility model is:
A kind of acupuncture needle, include needle body, needle point and needle handle, the front end of needle body is a needle point, it is characterized in that needle body is the metal needle tubing, the needle body needle tubing is built-in with heating wire, between needle tubing and the heating wire insulation system is arranged, heating wire is connected to form the loop at needle point and needle body place, and wherein the resistivity of needle body place heating wire is: the resistivity in the time of 20 ℃ is less than 9.78 * 10 -8(Ω m); The resistivity of needle point place heating wire is greater than 1 * 10 -7(Ω m).
The resistivity of described needle body place heating wire is preferably: the resistivity in the time of 20 ℃ is less than 2.83 * 10 -8(Ω m)
The preferred resistance wire of described heating wire; The heating wire that removes the needle point place plates the higher metal level of conductivity.
It is copper, silver, gold that described needle body place resistance wire plates the higher metal level of conductivity.
Described needle body is copper, silver, gold etc. for the metal needle tubing.
For realizing that needle point generates heat and temperature can be controlled and quantized purpose, this utility model acupuncture needle, include needle body, needle point and needle handle, the front end of needle body is a needle point, it is characterized in that needle body is the metal needle tubing, the needle body needle tubing is built-in with heating wire, and needle tubing and heating wire have insulation system, heating wire is connected to form the loop at needle point and needle body place, and wherein the resistivity of needle body place heating wire is: the resistivity in the time of 20 ℃ is less than 9.78 * 10 -8(Ω m); The resistivity of needle point place heating wire is greater than 1 * 10 -7(Ω m); The heating wire two ends link to each other with the two poles of the earth of current output device; Described current output device is by power supply, potential device, fairing, PCU Power Conditioning Unit.
The two poles of the earth of described heating wire two ends and current output device are connected to: it is a utmost point that heating wire connects the needle handle place, and heating wire connects the needle body place and is another utmost point.
The power indicating device is arranged in the described current output device, can displays temperature.
In this utility model in a hollow rustless steel needle tubing, install a resistance wire, this resistance wire removes the needle point place and plates the higher metal level of one deck conductivity through electric plating method, so just realized changing the resistivity of same heating wire, be placed in such heating wire and also just realized the puncture needle that needle point is heatable in the rustless steel needle tubing through special handling.Because needle tubing is an electric conductor, needle tubing and resistance wire have insulation system to realize heating wire and rustless steel needle tubing good insulation.
Above-mentioned acupuncture and moxibustion needle body, there are some microflutes on the surface of needle body, and the trend of microflute is the axis parallel longitudinal direction with needle body.The cross section of microflute can be that arc also can be a V-arrangement.The needle body of same outer diameter as, sectional area with circular cross-section is a maximum, resistance maximum when so the cross section is circular needle body inserting needle, pain is the strongest, many vertical microflutes have been offered on the surface of needle body, not only reduced needle body sectional area, reduced the inserting needle resistance, and when inserting needle, have guide effect, the pain when having alleviated inserting needle greatly.Vertical microflute on needle body surface has increased circumferential friction when twirlinging or rotating of the acupuncture needle in addition, has increased the pin sense.
The product that hyperthermia treatment of carcinoma is arranged at present, key be to make the tumor body absorb the heat energy effect to greatest extent, do not injure normal structure, thus the growth of anticancer.Using more local thermotherapy's technology roughly has: conduction of heat (heat perfusion), energy of electromagnetic field heating (radio frequency, microwave) and mechanical shock heating methods such as (ultrasound wave) in external conduction of heat (water-bath, wax apply), the body.But still there are many problems.Such as: 1. the scope of heating is difficult to the accurate control degree of depth of 2. heating and 3. can not 4. damages the normal structure scope more 5. because electromagnetic interference from tumor center heating inadequately, being difficult to when " start " thermometric 6. easily reflects from osseous tissue and other organizational interface, in a word, said method all is to make heat radiation from outside to inside, near heater position be heated big (as integumentary musculature, tumor superficial place).The heat energy that the tumor deep absorbs is less.And often concentrate inadequately, heat-energy losses is too much.Overheated for fear of epidermis, have to adopt surface blowing or put the cold water circulation and reduce skin temperature, use and alleviate skin injury.Although ultrasound wave can focus on, be subject to organize the influence of absorption and boundary reflection, ideal method is still directly introduced tumor center to heat energy.Moxibustion with electric warming needles can directly thrust the tumor middle part.When heat is 165 cards, during 40 minutes time, central temperature can be up to 560 ℃, and environment temperature changes between 44 ℃ and 47 ℃.This has just fundamentally changed the backheating approach of hyperthermia treatment of carcinoma.The damage of healthy skin does not take place under 47 ℃ usually, and the moxibustion with electric warming needles temperature is adjustable, if change electric current, the lifting thereupon of tumor temperature everywhere.In addition, moxibustion with electric warming needles is easy to operate, and is safe and reliable.
This utility model is to utilize electric energy to be converted to heat energy, and pin temperature scope can be controlled at 30 ℃-700 ℃, and temperature Centralized skin injury can not take place at the needle point position, has avoided traditional fire to burn and infringement at scalding of skin.Can be more than 350 ℃ with the pin temperature, differ 3 times in the external pin Wen Yuti, therefore working as temperature is increased to more than 350 ℃, can not produce the pain and the damage at skin place, raise with temperature, can cause the tissue inflammation reaction of needle point place contact, 700 ℃ can cause tissue necrosis even the carbonization around the needle point.The utlity model has the combined effect of acupuncture, warm pin, fiery pin.Behind input current, warmth sensation can penetrate the body deep and can conduct diffusion, and along with electric current increases, increase in temperature is same as fiery pin, and adjustable constant temperature, heat radiation can be introduced the body deep.
Following experimental example is used to further specify effect of the present utility model, and wherein said moxibustion with electric warming needles is this utility model embodiment 2.
Experimental example 1 moxibustion with electric warming needles is to the inhibiting laboratory observation of the portable cancer of mice
Materials and methods
One, moxibustion with electric warming needles is embodiment 2.
Two, tumor therapeuticing method
(1) laboratory animal and tumor source: mice model of forestomach scale cancer (GS-742) is taken from Tianjin Medical College tumor chamber (the 75th generation and 81 generations).The TAI that adopts this chamber to cultivate, mouse inbred lines (♀).Mus 8~12 weeks of age, body weight 16~22 grams.Average weight is 19 grams.
Mouse breast cancer (MC-615) is taken from pharmacological room of Shanxi Tumors Inst..Pure lines 615 mices of adopting Academy of Traditional Chinese Medicine, Shanxi Province animal housing to be cultivated.Mus age was 8~12 weeks, and body weight is 16~22 grams, on average weighs 19 grams.Male and female half and half.
Rat liver cancer is taken from institute of Materia Medica,Chinese Academy of Medical Sciences tumor chamber.The purebred Kunming mouse that adopts Chinese Academy of Medical Sciences's animal center to cultivate is female.Mus age was 8~12 weeks.Weight average is 24 grams.
(2) tumour transplatation: transplant mice model of forestomach scale cancer fritter inocalation method. tumor-bearing mice is put to death, peel off tumor.Choose peripheral well-grown tumor tissue. place in the sterile petri dish, remove blood vessel, connective tissue and slough. the fresh tumor tissue sterile saline that will keep: in wash 2~3 times, be cut into diameter and be about 2 millimeters tumor piece, it is subcutaneous to be inoculated in Mus right side buttocks.
Transplant mouse breast cancer and rat liver cancer suspension inoculation method.After putting to death tumor-bearing mice, under the sterile working, select the translucent flesh of fish sample tumor tissue of corpus carcinosus periphery, be cut into small pieces, put into dismembyator.Breast carcinoma and hepatocarcinoma were made into respectively 1: 10 and 1: 2 suspension, draw 0.1 milliliter with syringe.It is subcutaneous to inject the right buttocks of mice.
(3) grouping: to selected, mice is divided into two groups according to the random pair method of dividision into groups.Treatment group: do seance with moxibustion with electric warming needles.Matched group: the tumor of waiting is grown to organizing identical size with treatment, anesthesia back usefulness general acupuncture eight tumors withdrawal of needle after 40 minutes.
(4) moxibustion with electric warming needles treatment: when the tumor of waiting is grown to major diameter and is 0.7~1.0 centimetre, with mouse anesthesia, go in the middle of the tumor with hot pinprick then with the capable lumbar injection of pentobarbital sodium.It is 40 minutes that treatment time is selected in experiment for use, and therapeutic dose is 135 cards~136 cards.
(5) observed and recorded: treatment back mice weighs in for twice weekly and gross tumor volume (go out tumor length and width, thick three footpaths with vernier caliper measurement, with
Figure G2009201605167D00051
Length * wide * thick formula is calculated tumor body tax), find animal dead.At any time separate and cut record.Take by weighing tumor weight.
Except that first experiment lotus liver cancer mouse is dissected after treating 45.All the other each time experimental mouse are all cutd open inspection in treatment after 60 days.All get the tissue of internal organs such as tumor (or former trouble tumor locus), body Yuan lymph node, liver, board, lung, kidney, the heart, adrenal gland when the every example of first experiment is cutd open inspection and do pathological section for microscopic examination.Randomly draw 5 examples and do histological examination for every group during repeated experiments.Other survival mice is stayed and is done breeding and immunization experiment observation.
Three, the evaluation of antitumor action
(1) tumor cure rate, criterion of cure: tumor disappears fully, and naked eyes and microscope get off to see tumor tissues, treat and do not see recurrence in back 45 days.
Figure G2009201605167D00061
(2) the complete extinction rate of tumor.Standard fully disappears: treatment back tumor disappears fully. but dead before treatment 4 weeks to 45 of back day.After death naked eyes and apparent sharp mirror get off to see tumor tissues.
(3) inhibition rate of tumor growth: behind the animal dead or experiment when finishing.Take out tumor and take by weighing weight.Obtain the virgin amount of every group of average tumor, calculate inhibition rate of tumor growth by following formula.
(4) neoplasm metastasis rate: the judgement of neoplasm metastasis need rely on naked eyes and histological examination.Main internal organs and the tissue of checking comprises lung, liver,spleen,kidney, the heart, body surface, abdominal cavity and internal organs lymph node.
(5) average survival period: by only writing down the dead mouse date, calculating the average survival period that each is organized.
Experimental result
One, therapeutic outcome
Use the suitableeest therapeutic dose repeated experiments is treated and done to every kind of tumor, relevant every result, row day table 1,2,3.
Average survival period: kill because of cuing open in back 60 days, so actual survival day was greater than 60 days in treatment.Only hepatocarcinoma group mice maiden trial was cutd open in treatment and is killed in back 45 days, so its actual survival day was greater than 45 days.
Table 1: moxibustion with electric warming needles treatment mice model of forestomach scale cancer result
Figure G2009201605167D00065
Table 2: the result of breast carcinoma before the moxibustion with electric warming needles treatment mice
Figure G2009201605167D00071
Table 3: moxibustion with electric warming needles treatment hepatocarcinoma result
Figure G2009201605167D00072
Annotate * *: X 2Test P<0.01, significant difference has the highly significant meaning.
The lotus cancer mice that experimental example 2 moxibustion with electric warming needles are cured is to inoculating the effect of resisting of tumor of the same race
Experimental technique
One, the inoculation of tumor with inoculate: select lotus liver cancer mouse moxibustion with electric warming needles treatment back February, and reach 5 of clinical cure (naked eyes are seen, hands touch no tumor) persons and inoculate group (abbreviation inoculates group), and sex, body weight, Mus age and to inoculate 5 of purebred Kunming mouses that are complementary be matched group for curing.In 1: 2 cell suspension 0.1ml of every mice left side groin subcutaneous vaccination homology rat liver cancer.Measure 2 body weight and tumor size weekly, the general situation of record mice.Dissect it after 70 days.When dissected is got tissues such as tumor (or inoculation position skin), liver,spleen,kidney, the heart and lymph node, conventional film-making, and HE dyeing, light microscopic is checked down.Choose lotus glandular stomach scale cancer mice, set up according to above-mentioned same principle to inoculate group and matched group.Every group each 5, subcutaneous in left buttocks, the inoculation diameter is the homology tumor tissue piece of 0.2mm, and it is the same to measure inspection method.
Two, peripheral blood lymphocyte counting: January before inoculating and after inoculating.Cutting off Mus tail point gets blood smear and does differential blood count. the shared percentage ratio of statistics lymphocyte.
Three, serum protein electrophoresis: in January before inoculating and after inoculating, cut off the Mus tail about 80 μ l of glass capillary draw blood.Sintering capillary tube one end treats to separate out in 2-3 hour centrifugation 600rpm behind the serum.1 minute (LXJ4-01 centrifuge) gets 10 μ l serum.Drip on acetate film with thin slice, under 160 volts of voltages.Electrophoresis 40 minutes.Azocazmine dyeing after the acetic acid decolouring, is put on the serum electrophoresis scanner (IntergraphCH, Switzerland produces), and various one-tenth component curves in the serum albumin that draws are read shared percentage ratio of albumin (A) and globulin (G) and the ratio of A/G.
Four, tumor is resisted Evaluation on effect: from inoculate (inoculating group) or the inoculation (matched group) from, breeding observing 70 days.Dead person's statistics is within the routine number of death in 70 days.Inoculation back a few days tumor grows.But disappear again after a few days.And do not see recurrence in 70 days, be considered as tumor and disappear fully.Behind the animal dead or experiment when finishing, take out tumor and weigh, obtain every group of average tumor weight, calculate inhibition rate of tumor growth.By only writing down the dead mouse date.The hepatocarcinoma group was observed to 70 days, and glandular stomach scale cancer group was observed to 120 days.Obtain the arithmetic mean of its survival with statistic law.
Experimental result
One, antitumor inoculates effect: we have done first experiment and repeated experiments to two kinds of tumors.According to above-mentioned evaluation criteria, relevant Table I, the II of the results are shown in.
The Table I moxibustion with electric warming needles is cured the lotus liver cancer mouse and is inoculated the back result
Figure G2009201605167D00081
Figure G2009201605167D00091
The lotus glandular stomach scale cancer mice that the Table II moxibustion with electric warming needles is cured inoculates the back result
Figure G2009201605167D00092
Annotate: a. test inoculates group and compares the significant difference significance with matched group.
B. test inoculates group and compares with matched group, and significant difference has the highly significant meaning.
C. test inoculates group and compares the significant difference significance with matched group.
D. test inoculates group and compares with matched group, and significant difference has the highly significant meaning.
(1) comparison of death condition: in the first experiment, the lotus liver cancer mouse inoculates to organize in inoculation did not have 1 death in back 70 days, and matched group is all dead.In the repeated experiments, inoculate to organize and had only 1 death in back 70 days and all death of matched group in inoculation.Twice experiment contrast group mortality rate all is higher than and inoculates group.The two significant difference has highly significant meaning (P<0.01).In the first experiment, lotus glandular stomach scale cancer mice dead 3/5,120 day on the 70th is dead 4/5, and matched group is all dead in 60 days: in the repeated experiments.Inoculating group inoculated back 90 days dead 2/5: and matched group is all dead.Repeated experiments result learns by statistics and handle, and group difference has the highly significant meaning.
(2) tumor growth and decline situation: in the first experiment, hepatocarcinoma inoculates the group mice and grew visible tumor in back 7 days in inoculation.Slowly increase.Stopped to increase to 15 days.All disappear after 20 days.The matched group tumor increases rapidly.To animal dead.Contrast two groups of tumor regression rates.Significant difference has the highly significant meaning.In the repeated experiments.Inoculate mice and grow tumor after 6 days in inoculation.Wherein disappear after 3 in 13 days.Two tumors are grown up gradually in addition, respectively at inoculation back 55 days and death on the 92nd.During first the experiment, the glandular stomach scale cancer inoculates group mouse tumor poor growth.Wherein die from and inoculate in back 60 days for 3, die from for 1 and inoculate back 115 days.In addition die from and inoculate back 160 days for 1, and control group mice is all dead in 55 days.During repeated experiments, inoculate in the group 1 and do not see tumor growth.1 in inoculating back 8 days.2 in inoculating back 15 days, and 1 tumor occurs in inoculating back 32 days beginnings in addition.And in the matched group 4 in kind after 8 days.1 grew visible tumor in back 12 days in inoculation, and ramp is until dead mouse.
Two, the end shared ratio of blood lymphocyte slightly: get the end slightly blood do differential blood count, the shared percentage ratio of its lymphocyte is listed in Table III.Show as can be known the shared ratio of peripheral blood lymphocyte before inoculating thus.Inoculate group and compare no significant difference with matched group.Yet after the inoculation.Inoculate the ratio that accounts for of group lymphocyte still with inoculation before close.Or slightly reduce.Concerning the hepatocarcinoma group.Compare with inoculating group, significant difference has the highly significant meaning.
Three, serum protein electrophoresis result: now the Table IV that the results are shown in of serum protein electrophoresis.Table as can be known thus.Lotus cancer mice bimester that moxibustion with electric warming needles is cured after, the shared ratio of serum globulin obviously increases, and causes the Archon phenomena of inversion; With the matched group ratio.Significant difference significance (glandular stomach scale cancer kind group) or highly significant meaning (hepatocarcinoma).But, plant January again after.The shared ratio of globulin has obvious decline, relatively two groups.The significant difference nonsignificance.Above-mentioned experimental result shows that the lotus liver cancer mouse that moxibustion with electric warming needles is cured has the obvious suppression effect to planting tumor of the same race again.8/10 mice is disappeared again after growing tumor.Thereby prolonged the survival period of mice.Reduced mortality rate.In other words, the mice of being cured has very significantly immunity to inoculating tumor of the same race.Lotus hepatocarcinoma is cured before the back mice inoculates, and shared ratio and the matched group of blood lymphocyte is close slightly at the end.But after inoculating January.The shared ratio of matched group lymphocyte is lower than significantly and inoculates group.Inoculate the group mice before again by inoculation, the shared ratio of serum globulin is higher than matched group very significantly, causes Archon albumen than inverted phenomenon.The shared ratio of serum globulin descends to some extent after inoculating January, causes to inoculate to organize with matched group to compare the significant difference nonsignificance.Lotus glandular stomach scale cancer mice inoculates after curing.Exhausted too many number (9/10) can only slow down and inoculates growth of tumor, and tumor is disappeared fully.Thereby delayed the death of animal.Inoculating the group mice inoculates back lymphocyte shared percentage ratio and decreases.Though comparison is according to high slightly.But the two significant difference nonsignificance.Serum ball egg is by than being higher than matched group significantly before inoculating, inoculate January after.The shared ratio of serum globulin obviously descends.With matched group comparative statistics difference nonsignificance.
Table III peripheral blood lymphocyte counting contrast table
* inoculate group and compare P<0.01 with matched group.Significant difference has the highly significant meaning.
Table IV electric heating acupuncture cancer is white to mice serum, the influence of globulin
Figure G2009201605167D00112
Annotate: a. compares the significant difference significance with matched group.
B. than significant difference the highly significant meaning is arranged with matched group.
Experimental example 3 moxibustion with electric warming needles treatment skin carcinoma curative effect and mechanism research
1. clinical data
1.1 physical data
This group patient is totally 100 examples, and wherein 46 just are the letter patient of institute, and 59 examples are the outpatient.All case all is diagnosed as skin carcinoma through pathologic finding, and does not all find histoorgan and far-end lymph metastasis sign.
Male's 66 examples among the 100 routine patients, women's 34 examples; Minimum 17 years old of age, maximum 76 years old, 6.15 years old mean age; The course of disease is the shortest 2 months, reaches 20 years most.Occupation: miner's 42 examples, other workman's 18 examples, peasant's 12 examples, cadre's 13 examples, teacher's 4 examples, citizen's 11 examples.The cause of disease: person's 29 examples that contact the radioactive mineral for a long time, chronic ulcer repeated infection disunion person 24 examples, outer cavity block white lesions the infected's 8 examples of scratching are for a long time scalded, disunion person's 10 examples after the wound, not quite clear person's 29 examples of other cause of disease.
The past treatment situation.After this group patient falls ill all through the conventional dressing change of surgery.Radiation cure 7 examples wherein, cold therapy 12 examples.5 examples are recurred in laser therapy, personal folk prescription external treatment 9 examples, recurrence after operation 6 examples.All the other 61 examples are without special treatment.
1.2 tumor situation
Among the 100 routine patients, scale cancer 59 examples, cancer in situ 35 examples, basal cell carcinoma 6 examples.197 of cancer pieces take place altogether, 2 skin lesion person 19 people wherein occur.3 skin lesion person 12 people, 55 skin lesion person 1 people, all the other are a skin lesion person.
Size: cancer piece the maximum reaches 12 * 6 * 4.5 centimetres.Wherein single cancer block length footpath is 41 of 3 centimetres of persons, 4 of 12 centimetres of persons, 1 of 8 centimetres of person, 36 of 6 centimetres of persons.49 of 1~2 centimetre of persons are less than 66 of 1 centimetre of persons.
Position: by site distribution.The patient of women's head-ornaments portion 29 examples, cervical region patient 9 examples.Pudendum patient 8 examples.Upper limb and hand 19 examples.Heel portion and calf patient 15 examples, finger patient 17 examples, other position 3 examples.
The main concomitant symptoms:
Pain: having 88 routine patients in this group has in various degree pain.Wherein having an intense pain is difficult to bear receptor's 21 examples, and moderate pain can be born receptor 29 people.Mild pain person 38 examples.
Pruritus: have 79 routine patients in this group and feel pruritus.Wherein obvious pruritus person's 39 examples.Paroxysmal pruritus person 11 examples, slight pruritus person 29 people.
1.3 pathological staging
This group case is all according to the clinical symptoms sign, and the binding of pathological inspection is made a definite diagnosis.According to be not true to type in the skin carcinoma proliferation of cells what.Skin carcinoma can be divided into level Four.
The I level: the cell that is not true to type is lower than 25%, and the oncocyte group does not exceed the corium scope.Basal layer is complete or imperfect, and the angle pearl is many, the complete keratinization in center, and intradermal has obvious inflammatory reaction.This group has 56 examples.
The II level: the cell that is not true to type surpasses 25%, and the oncocyte group invades the corium deep layer.Pearl is few at the angle.Center parakeratosis, its Intradermal inflammatory reaction is lighter.This group has 27 examples.
The III level: the cell that is not true to type surpasses 50%, and keratinization is not obvious.The angle pearl disappears, and karyokinesis is remarkable, and inflammatory reaction on every side is not obvious.This group has 18 examples.
The IV level: the cell that is not true to type surpasses 75%.Nearly all squamous cell all is not true to type, and karyokinesis resembles many.Cannot see the keratinization situation fully.This group does not have this type of patient.
1.4 differentiation of symptoms and signs for classification of syndrome
Clinical symptoms according to skin lesion.Whole body performance in conjunction with the patient is summarised as three pattern of syndrome with this group case.
(1) stagnation of liver-QI blood-dryness type: the skin ulcer type is dry.The high skin ulcer face that rises in edge is uneven. and crust set difficulty is taken off.Have slightly and touch that then oozing of blood is more than, or pain or itch its stench of distinguishing the flavor of.If disposition fluctuation or emotional depression be sx then, accompany depressed irritability.Diseases such as side of body rib distension.Tongue body extra dry red wine slight of stature.Thin white fur of tongue or pale yellow.Weak pulse is carefully heavy.This organizes 46 examples.
(2) insufficiency of the spleen damp-obstruction type: the skin ulcer face is dark and gloomy.The top of the sore raptured shape is as the heap foxtail millet.Or high of edge is hard.Or ulcer do not heal, and routs up in the Nu, and secretions is stench thin.The companion whole body is weak, indigestion and loss of appetite abdominal distention.Diarrhea.There is indentation on pale tongue or limit, thick and greasy fur.Moderate pulse and moistening.This organizes 31 examples.
(3) skin ulcer sense pathogenic wind toxic type: former trouble skin infection or wound once.With the passing of time not heal. bulbar conjunctiva polyp exceeds, and color and luster is dark and gloomy, the stench pus of time stream, sufferings are obvious.It is heavy when time thes be light.Dark tongue quality or ecchymosis, petechia are arranged, weak pulse is puckery.This organizes 23 examples.
2. Therapeutic Method
2.1 utensil adopts No. 6 moxibustion with electric warming needles of this utility model embodiment 2 moxibustion with electric warming needles instrument, embodiment 1 and the quasiconductor thermodetector that Beijing 1412 is developed.
2.2 operational approach
The skin part routine disinfection is removed pus and blood, and then with 2% lignocaine local anesthesia, consumption is decided according to tumor body size, about general 2ml.According to tumor body size, position, shape, sting, thrust straightly, stab diagonally, enclose and thrust the tumor body moxibustion with electric warming needles is flat. connection moxibustion with electric warming needles instrument, energized.
According to the state of an illness and patient's tolerance degree tumor body temperature degree is controlled between 43~45 ℃.Every day or the next day once.10 times is a course of treatment, has a rest between the course of treatment 3~5 days.Belong to the dry person of congestion of the liver, with acupuncture needle Jia Citai: in, gb 34 (two); Insufficiency of the spleen wet resistance person adds thorn tsu san li, rich and prosperous (two); Skin ulcer sense pathogenic wind toxic person adds thorn windy mansion, the sea of blood (two).2~3 courses of treatment of general treatment.
2.3 observation index
(1) gross tumor volume size variation: all case treatment front and back are accurate to 0.1 centimetre all with tape measure tumor body size.
(2) pathological tissue inspection: get biopsy before the treatment to clarify a diagnosis.When finishing, treatment gets biopsy with contrast at same position.
(3) variation of clinical symptoms: at every turn treat in the equal itemized record treatment and the variation of treatment back patient's symptom.
2.4 lab testing
(1) immunoglobulin content is measured before and after the treatment.
(2) the E-rosette forming rate is measured.
3. therapeutic outcome
3.1 the solid tumor curative effect that criterion of therapeutical effect is formulated according to International Union Against Cancer, this group criterion of therapeutical effect is:
(1) alleviate (CR) fully: the tumor sign all disappears during the treatment;
(2) part is alleviated (PR): tumor is dwindled and is surpassed 50% (products of two diameters).New tumor sign does not appear during the treatment;
(3) improve (ImPr): tumor is dwindled and is less than 50%, (products of two diameters):
(4) tumor size no change (NL) during the treatment;
(5) gross tumor volume increases or new tumor (P) occurs during the treatment.
3.2 therapeutic outcome
This is organized 100 routine skin carcinoma patient treatments and the results are shown in Table 1.
Table 1 moxibustion with electric warming needles is treated the curative effect (unit: example) of 100 routine skin carcinomas
Figure G2009201605167D00151
Figure G2009201605167D00161
As seen from Table 1, the complete remission rate of this group is 56.00%, and effective percentage is 92.00%.
3.3 clinical symptoms is improved situation
Pain person's 88 examples are alleviated 83 examples after the moxibustion with electric warming needles treatment in various degree.Remission rate is 94.32%.The light and heavy degree of pain is relevant with the improvement degree, and pain degree is heavy more, and the improvement amplitude is big more.Illustrate that moxibustion with electric warming needles has certain effect to alleviating cancerous pain.
Pruritus person's 79 examples.Alleviate 75 examples after the moxibustion with electric warming needles treatment, remission rate is 94.94%.
3.4 lab index
In this group case, have 75 examples to measure immune globulin Pseudobulbus Bletillae (Rhizoma Bletillae) E-rosette forming rate before and after treatment, its statistical result sees Table 2, table 3.
Table 2 75 routine skin carcinoma immunoglobulin contents are measured
Figure G2009201605167D00162
The contrast of table 3 75 routine skin carcinoma E-rosette forming rates
Figure G2009201605167D00163
Statistical result shows, patient's immunoglobulin content and E-rosette forming rate difference highly significant before and after the treatment illustrate that treatment back patient's immune function improves.
4. efficacy analysis
4.1 cell differentiation and curative effect
In the therapeutic process of malignant tumor.The differentiation degree of cell is significant to decision Therapeutic Method and curative effect, and the relation of cell differentiation and curative effect sees Table 4 in this group case.
Table 4 cell differentiation and curative effect (unit: example)
Figure G2009201605167D00171
Can find out that from table 4 complete remission rate of worker's level skin carcinoma is 75.00%.The II level is 40.74%, and the III level is 17.05%.Worker's level and II level, III level compare its difference significance (P<0.05).Prompting: cell differentiation is poor more.Curative effect is low more.
4.2 determination of treatment based on pathogenesis obtained through differentiation of symptoms and signs and curative effect
The relation of different pattern of syndrome and curative effect sees Table 5.
Table 5 pattern of syndrome and curative effect
Figure G2009201605167D00172
Statistical result shows that three kinds of pattern of syndrome skin carcinomas are treated through moxibustion with electric warming needles, symptom effective percentage no significant difference (P>0.05).
Description of drawings
Below in conjunction with accompanying drawing this utility model is described in further detail.
Accompanying drawing 1 is the cutaway view of this utility model structure.
Accompanying drawing 2 is sketch maps of moxibustion with electric warming needles and current output device (heater)
Needle handle 1, needle body 2, high strength insulating barrier 3, plating resistance wire 4, needle point 5, needle point place resistance wire 6
Specific implementation method
Embodiment 1
Structure of the present utility model is shown in Figure 1, comprise needle body 2, needle point 5, needle handle 1, needle body 2 is the rustless steel needle tubing, penetrate resistance wire 4,5, penetrate and be high strength insulating barrier 3 between resistance wire 4,5 and the needle body 2, the resistance wire at needle body place is for electroplating resistance wire 4, being coated with metal level is copper, the resistance wire 5 at needle point place does not have electroplated metal layer, resistance wire is a constantan, needle point place resistance wire is connected to form the loop at needle point and needle body place, and making resistance wire connect the needle handle place is a utmost point, and heating wire connects the needle body place and is another utmost point.
Embodiment 2
This utility model as shown in Figure 2, the moxibustion with electric warming needles structure is with accompanying drawing 1, comprise needle body 2, needle point 5, needle handle 1, needle body 2 is the rustless steel needle tubing, penetrate resistance wire 4,5, penetrate and be high strength insulating barrier 3 between resistance wire 4,5 and the needle body 2, the resistance wire at needle body place is for electroplating resistance wire 4, being coated with metal level is copper, the resistance wire 5 at needle point place does not have electroplated metal layer, needle point place resistance wire is connected to form the loop at needle point and needle body place, and making resistance wire connect the needle handle place is a utmost point, and resistance wire connects the needle body place and is another utmost point.Current output device is made up of power supply, potential device, fairing, PCU Power Conditioning Unit, power indicating device.A utmost point that connects the needle handle place by resistance wire, resistance wire connects the output of another utmost point realization electric current at needle body place, because needle body place resistance wire is electroplated into the low metal of resistivity, needle body place resistance wire temperature basically is no more than 47 ℃, needle point place resistance wire then can be realized heating, by the control power adjustments, the temperature of control needle point.
Above-described only is preferential embodiment of the present utility model; be noted that for the person of ordinary skill of the art, under the prerequisite of this utility model principle; can also make some distortion and improvement, also this is considered as belonging to protection of the present utility model for these.

Claims (11)

1. acupuncture needle, comprise needle body, needle point and needle handle, the front end of needle body is a needle point, it is characterized in that needle body is the metal needle tubing, needle tubing is built-in with heating wire, between needle tubing and the heating wire insulation system is arranged, heating wire is connected to form the loop at needle point and needle body place, and wherein the resistivity during 20 ℃ of needle body place heating wires is less than 9.78 * 10 -8The resistivity of Ω m, needle point place heating wire is greater than 1 * 10 -7Ω m.
2. acupuncture needle as claimed in claim 1, the resistivity when it is characterized in that 20 ℃ of needle body place heating wires is less than 2.83 * 10 -8Ω m.
3. acupuncture needle as claimed in claim 2 is characterized in that heating wire is a resistance wire.
4. acupuncture needle as claimed in claim 2 is characterized in that the heating wire that removes the needle point place plates the higher metal level of conductivity.
5. acupuncture needle as claimed in claim 2 is characterized in that it is copper, silver or golden that described needle body place resistance wire plates metal level.
6. acupuncture needle as claimed in claim 1 is characterized in that described needle body metal needle tubing is copper, silver or acupuncture needle pipe.
7. as described any one acupuncture needle of claim 1-6, it is characterized in that the heating wire two ends link to each other with the two poles of the earth of current output device; Described current output device comprises power supply, potential device, fairing, PCU Power Conditioning Unit.
8. acupuncture needle as claimed in claim 7, it is characterized in that the two poles of the earth of heating wire two ends and current output device are connected to: it is a utmost point that heating wire connects the needle handle place, heating wire connects the needle body place and is another utmost point.
9. acupuncture needle as claimed in claim 7 is characterized in that the power indicating device is arranged in the described current output device.
10. acupuncture needle as claimed in claim 1 is characterized in that there are some microflutes on the surface of needle body, and the trend of microflute is the axis parallel longitudinal direction with needle body.
11. acupuncture needle as claimed in claim 7 is characterized in that there are some microflutes on the surface of needle body, the trend of microflute is the axis parallel longitudinal direction with needle body.
CN2009201605167U 2009-06-26 2009-06-26 Acupuncture needle Expired - Fee Related CN201481788U (en)

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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101862504A (en) * 2010-06-25 2010-10-20 卢恩光 Nano electrotherapy needle
CN105726305A (en) * 2016-02-15 2016-07-06 中国科学技术大学 Acupuncture needle
CN109199853A (en) * 2018-11-06 2019-01-15 阿拉善盟蒙医医院(阿拉善盟蒙医药研究所) Acupuncture needle and its application for treating cold arthritis

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101862504A (en) * 2010-06-25 2010-10-20 卢恩光 Nano electrotherapy needle
CN105726305A (en) * 2016-02-15 2016-07-06 中国科学技术大学 Acupuncture needle
CN105726305B (en) * 2016-02-15 2018-04-10 中国科学技术大学 A kind of acupuncture needle
CN109199853A (en) * 2018-11-06 2019-01-15 阿拉善盟蒙医医院(阿拉善盟蒙医药研究所) Acupuncture needle and its application for treating cold arthritis

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