CN201299648Y - Equipment for automatic quantifying damages of peripheral nerves of experimental animals - Google Patents
Equipment for automatic quantifying damages of peripheral nerves of experimental animals Download PDFInfo
- Publication number
- CN201299648Y CN201299648Y CNU2008201555303U CN200820155530U CN201299648Y CN 201299648 Y CN201299648 Y CN 201299648Y CN U2008201555303 U CNU2008201555303 U CN U2008201555303U CN 200820155530 U CN200820155530 U CN 200820155530U CN 201299648 Y CN201299648 Y CN 201299648Y
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- damage
- pick
- piston
- utmost point
- movable
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Abstract
The utility model relates to equipment for automatic quantifying damages of peripheral nerves of experimental animals. The equipmen comprises damage forceps, a power device and a control device. A fixed pole and a movable pole are arranged on the damage forceps. A metal hinge and a sensor are installed on the surface of the movable pole. A metal frame is further arranged on the damage forceps and wraps the fixed pole, the movable pole, the sensor, a reset ring, a ladder-type tongue depressor, a flexible component, and a first piston, wherein the movable ladder-type tongue depressor is arranged on the surface of the sensor; one end of the reset ring is connected with the movable pole, and the other end is connected with the ladder-type tongue depressor; one end of the flexible component is connected with the ladder-type tongue depressor, and the other end is fixed in the wall of the metal frame; and the tail end of the first piston is connected with a hydraulic pipe. With an accuracy of no lower than 95%, the device is suitable for neurologic damages in deep and narrow spaces. Controlled by an electronic program, the device eliminates artificial factors and provides controllable and adjustable damage force and duration and high comparability in damage degree.
Description
[technical field]
This utility model relates to automatic ration damage equipment, specifically, is about a kind of laboratory animal peripheral nerve automatic ration damage equipment.
[background technology]
In the modern medicine, following several technology are adopted in the nerve injury of laboratory animal: 1, clamp damage technology: use quantitative, the regularly damage of specific engaging clamp.2, impact damage technology: vertically be put in neural top with a blunt round end batten, counterweight is fully vertically freely fallen from eminence, impact batten, cause neural indirect stroke to hinder.3, stretch injury technology: form by pulling device-suspender belt-nerve, nerve is straightened causes neural tension injury animal model.4, crush injury technology: extruding causes nervous lesion during similar hypertonia.There is following shortcoming in above technology: the clamp damage is big to operator's dependency, and the different operating person is difficult to be consistent to the damage of nerve, and difficult accurate quantification, and the damage power of single clamp is fixed or is uncontrollable.Impact damage equipment complexity, complex operation, wound is big, and laboratory animal mortality rate height is compared with the clamp wound, and the rate of causing injury is low slightly, is not suitable for deep small space damage.Its device complexity of causing injury of stretch injury, operating procedure are more, and the operating process difficulty is bigger, and are mainly used in neural two ends tractive and cause the damage of neuraxon's property, are not suitable for being applied to neural partial damage, more are not suitable for being positioned at the damage of brain deep nerve.The degree of injury of crush injury can't be quantitative, is difficult to guarantee to cause the nerve injury animal model of same degree.
[summary of the invention]
The purpose of this utility model is that a kind of laboratory animal peripheral nerve automatic ration damage equipment is provided.
For achieving the above object, the technical scheme that this utility model is taked is: described equipment comprises the damage tweezer, power set and control device, be provided with the fixed pole and the movable utmost point in the described damage tweezer, activity extremely surface is provided with the metal hinge, pick off, also be provided with metal frame in the described damage tweezer, hold fixed pole in the metal frame, the movable utmost point, pick off, reseting ring, trapezoidal pressure tongue, elastomeric element, first piston, sensor surface are placed an active trapezoidal pressure tongue, the reseting ring one end connection activity utmost point, the other end connects trapezoidal pressure tongue, and elastomeric element one end connects trapezoidal pressure tongue, and the other end is fixed in the metal frame wall, the tail end of described first piston connects hydraulic tube, the hydraulic tube other end connects second piston in the power set, and the first piston side is connected with the movable utmost point by fixed frame, and the side of fixed pole is provided with pick off input and output pipe, pick off input and output Guan Yiduan connects pick off, and the other end connects control device.
Described pick off is a Hall FS touch force sensor, and elastomeric element is a spring.
The tail end of the described movable utmost point and fixed pole tail end are fused to bipolar link.
This utility model advantage is:
1, degree of injury is accurate, and the degree of accuracy of this equipment is not less than 95%.
2, this equipment is fit to the nerve injury in deep, the small space.
3, adopt electronic program control, got rid of artificial factor, controllable joint of the power of damage and time, the degree of damage has the comparability of height.
4, realized automatic control.
5, cost is low, and is simple and practical.
[description of drawings]
Accompanying drawing 1 is the structural representation of laboratory animal peripheral nerve automatic ration damage equipment.
Accompanying drawing 2 is sketch maps of A-A direction in the accompanying drawing 1.
The Reference numeral and the ingredient that relate in the accompanying drawing are as follows:
1. damage tweezer 2. control device
3. power set 10. bipolar links
11. metal frame 12. fixed poles
13. the movable utmost point 14. pick offs
15. reseting ring 16. trapezoidal pressure tongues
17. elastomeric element 18. first pistons
19. metal hinge 141. pick off input and output pipes
181. hydraulic tube
[specific embodiment]
Below in conjunction with embodiment and with reference to accompanying drawing this utility model is further described.
Please referring to Fig. 1, Fig. 1 is the structural representation of laboratory animal peripheral nerve automatic ration damage equipment, and described equipment is provided with damage tweezer 1, control device 2, power set 3.Be provided with the fixed pole 12 and the movable utmost point 13 in the damage tweezer 1.Please referring to Fig. 2, the movable utmost point 13 is connected with tail end in the tail end cut-out and with metal hinge 19 makes it to have motility, pick off 14 is installed on the surface of the movable utmost point 13.Please, also be provided with metal frame 11 in the described damage tweezer 1, hold the fixed pole 12 of part in the described metal frame 11, the movable utmost point 13 of part, pick off 14, reseting ring 15, trapezoidal pressure tongue 16, elastomeric element 17, the first piston 18 of part referring again to Fig. 1.An active trapezoidal pressure tongue 16 is placed on pick off 14 surfaces, the reseting ring 15 1 end connection activity utmost points 13, and the other end connects trapezoidal pressure tongue 16.Elastomeric element 17 1 ends connect trapezoidal pressure tongue 16, and the other end is fixed in metal frame 11 walls.The tail end of described first piston 18 connects hydraulic tube 181, and hydraulic tube 181 other ends connect second piston (not indicating) in the power set 3.First piston 18 sides are connected with the movable utmost point 13 by fixed frame 11.The tail end and fixed pole 12 tail ends of the movable utmost point 13 are fused to bipolar link 10.The side of fixed pole 12 is provided with pick off input and output pipe 141, and pick off input and output pipe 141 1 ends connect pick off 14, and the other end connects control device 2.Pick off 14 is Hall FS touch force sensors, and elastomeric element 17 is springs.Not only fixedly the fixed pole 12 and the movable utmost point 13 are in same plane motion for metal frame 11, and when guaranteeing in working order, first piston 18 is close to the inwall of metal frame 11.The front end of the movable utmost point 13 is rifle shape shape (see figure 2)s, is convenient to operator's operation.Described power set 3 are micromachines of band deceleration device.Be provided with in the power set 3: belt, nut, screw rod, second piston.By belt transmission, drive fixed nut, make screw motion, drive the second piston activity, through the hydraulic pressure conduction, make second piston motion of the trapezoidal pressure tongue top in the damage tweezer and then form compressing.Be provided with in the control device 2 and amplify comparison circuit, the one piston motion of time-delay relay and then form compressing.Be provided with the control circuit that amplifies comparison circuit, time-delay relay, circuit for controlling motor, relay composition in the control device 2.Need to prove: what described fixed pole and movable utmost point material adopted is bipolar employed material in the medical bipolar electrocoagulator.
Use of the present utility model: at first under a constant-voltage DC source, using counterweight demarcates the damage tweezer, draw the output valve of the situation lower sensor of a series of different power, when each damage, comparison circuit is amplified in the sensor output signal access then, and the fiducial value of this circuit can be regulated as required before damage.Be 50g for example to a laboratory animal peripheral nerve injury power, predetermined value in the control device 2 is made as 50g, the operator hands bipolar link 10 places, a laboratory animal peripheral nerve is placed fixed pole 12 and the movable utmost point 13 centres, second piston that power set 3 start in the power set 3, second piston passes to hydraulic tube 181 with power, hydraulic tube 181 passes to first piston 18 with power, promote first piston 18 motions, first piston presses 18 to squeeze trapezoidal pressure tongue 16, and compressing is implemented to fixed pole in trapezoidal pressure tongue 16 extrusion Hall FS touch force sensor pick offs 14 and the drive activity utmost point 13 tops.After compressing arrives predetermined value, send signal by control device 2 and give power set 3, make power set 3 stop motions, keep pressing time to control by time-delay relay, in continuing pressing time, the power of 2 pairs of compressings of control device is monitored (output valve of monitoring sensor) at any time.In at this moment, if find output valve less than predetermined value, control device 2 sends signal again, allows power set 3 start power, makes pressure be maintained to predetermined value.Adopt damage tweezer clamp mode to damage, the damage tweezer adopts lever principle, effort design, and Hall FS touch force sensor is installed, and has accuracy height, stable, the long-lived feature of output.This damage tweezer can be regulated in 0-150g power scope as required.Adopt motor, belt gear, piston drive, the hydraulic pressure conduction has easy to use, the adjustable characteristics of injuring speed.Adopt high sensitivity to amplify comparison circuit to the sensor output signal amplification ratio, its degree of accuracy is greater than 95%.The control of employing electronic program.Whole damage process need not human intervention after the parameter adjustment, make degree of injury controlled, accurate, can repeat.Have time-delay mechanism, may command continues the damage time (this device is delayed time adjustable at 0-60 second).
The above only is a preferred implementation of the present utility model; should be pointed out that for those skilled in the art, under the prerequisite that does not break away from this utility model principle; can also make some improvement and replenish, these improvement and replenish and also should be considered as protection domain of the present utility model.
Claims (3)
1. a laboratory animal peripheral nerve automatic ration damages equipment, it is characterized in that, described equipment comprises the damage tweezer, power set and control device, be provided with the fixed pole and the movable utmost point in the described damage tweezer, activity extremely surface is provided with the metal hinge, pick off, also be provided with metal frame in the described damage tweezer, hold fixed pole in the metal frame, the movable utmost point, pick off, reseting ring, trapezoidal pressure tongue, elastomeric element, first piston, sensor surface is placed an active trapezoidal pressure tongue, the reseting ring one end connection activity utmost point, and the other end connects trapezoidal pressure tongue, elastomeric element one end connects trapezoidal pressure tongue, the other end is fixed in the metal frame wall, and the tail end of described first piston connects hydraulic tube, and the hydraulic tube other end connects second piston in the power set, the first piston side is connected with the movable utmost point by fixed frame, the side of fixed pole is provided with pick off input and output pipe, and pick off input and output Guan Yiduan connects pick off, and the other end connects control device.
2. equipment according to claim 1 is characterized in that, described pick off is a Hall FS touch force sensor, and elastomeric element is a spring.
3. equipment according to claim 1 is characterized in that, the tail end of the described movable utmost point and fixed pole tail end are fused to bipolar link.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CNU2008201555303U CN201299648Y (en) | 2008-11-18 | 2008-11-18 | Equipment for automatic quantifying damages of peripheral nerves of experimental animals |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CNU2008201555303U CN201299648Y (en) | 2008-11-18 | 2008-11-18 | Equipment for automatic quantifying damages of peripheral nerves of experimental animals |
Publications (1)
Publication Number | Publication Date |
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CN201299648Y true CN201299648Y (en) | 2009-09-02 |
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Application Number | Title | Priority Date | Filing Date |
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CNU2008201555303U Expired - Fee Related CN201299648Y (en) | 2008-11-18 | 2008-11-18 | Equipment for automatic quantifying damages of peripheral nerves of experimental animals |
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CN (1) | CN201299648Y (en) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN102772258A (en) * | 2012-07-27 | 2012-11-14 | 朱亚中 | Nerve panting clamp |
CN106061526A (en) * | 2013-12-23 | 2016-10-26 | 内斯特斯公司 | Hydraulic assembly of a generator of medium-pressure and high-pressure pulsed or non-pulsed jets |
-
2008
- 2008-11-18 CN CNU2008201555303U patent/CN201299648Y/en not_active Expired - Fee Related
Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN102772258A (en) * | 2012-07-27 | 2012-11-14 | 朱亚中 | Nerve panting clamp |
CN106061526A (en) * | 2013-12-23 | 2016-10-26 | 内斯特斯公司 | Hydraulic assembly of a generator of medium-pressure and high-pressure pulsed or non-pulsed jets |
CN106061526B (en) * | 2013-12-23 | 2019-11-26 | 波士顿科学有限公司 | The hydraulic package of medium and high pressure pulse or non-pulse jet generator |
US10758678B2 (en) | 2013-12-23 | 2020-09-01 | Boston Scientific Limited | Hydraulic assembly of a generator of medium-pressure and high-pressure pulsed or non-pulsed jets |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
C14 | Grant of patent or utility model | ||
GR01 | Patent grant | ||
C17 | Cessation of patent right | ||
CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20090902 Termination date: 20121118 |