CN201256969Y - Multi-modality mammary gland blood-oxygen function imagine system - Google Patents
Multi-modality mammary gland blood-oxygen function imagine system Download PDFInfo
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- CN201256969Y CN201256969Y CNU2008201905129U CN200820190512U CN201256969Y CN 201256969 Y CN201256969 Y CN 201256969Y CN U2008201905129 U CNU2008201905129 U CN U2008201905129U CN 200820190512 U CN200820190512 U CN 200820190512U CN 201256969 Y CN201256969 Y CN 201256969Y
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- 210000005075 mammary gland Anatomy 0.000 title claims description 93
- 229910052760 oxygen Inorganic materials 0.000 claims abstract description 102
- 239000001301 oxygen Substances 0.000 claims abstract description 102
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical group [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 claims abstract description 75
- 239000008280 blood Substances 0.000 claims abstract description 75
- 210000004369 blood Anatomy 0.000 claims abstract description 75
- 238000004458 analytical method Methods 0.000 claims abstract description 52
- 238000003384 imaging method Methods 0.000 claims abstract description 24
- 230000000877 morphologic effect Effects 0.000 claims abstract description 8
- 238000012545 processing Methods 0.000 claims description 51
- 230000003287 optical effect Effects 0.000 claims description 32
- 239000000523 sample Substances 0.000 claims description 19
- 238000000034 method Methods 0.000 claims description 16
- 238000001228 spectrum Methods 0.000 claims description 9
- 238000004891 communication Methods 0.000 claims description 8
- 238000003745 diagnosis Methods 0.000 abstract description 12
- 230000005540 biological transmission Effects 0.000 description 20
- 210000001519 tissue Anatomy 0.000 description 14
- 210000004204 blood vessel Anatomy 0.000 description 9
- 241001269238 Data Species 0.000 description 8
- 239000004744 fabric Substances 0.000 description 6
- 206010006187 Breast cancer Diseases 0.000 description 5
- 208000026310 Breast neoplasm Diseases 0.000 description 5
- 210000000481 breast Anatomy 0.000 description 4
- 201000008275 breast carcinoma Diseases 0.000 description 4
- 201000011510 cancer Diseases 0.000 description 3
- 238000006243 chemical reaction Methods 0.000 description 2
- 230000003211 malignant effect Effects 0.000 description 2
- 210000002445 nipple Anatomy 0.000 description 2
- 230000001575 pathological effect Effects 0.000 description 2
- 230000000505 pernicious effect Effects 0.000 description 2
- 230000001105 regulatory effect Effects 0.000 description 2
- 238000004148 unit process Methods 0.000 description 2
- 206010027476 Metastases Diseases 0.000 description 1
- 206010066901 Treatment failure Diseases 0.000 description 1
- 238000013459 approach Methods 0.000 description 1
- 208000030270 breast disease Diseases 0.000 description 1
- 238000011161 development Methods 0.000 description 1
- 238000002059 diagnostic imaging Methods 0.000 description 1
- 238000002405 diagnostic procedure Methods 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 238000013399 early diagnosis Methods 0.000 description 1
- 238000003708 edge detection Methods 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 208000013210 hematogenous Diseases 0.000 description 1
- 230000009401 metastasis Effects 0.000 description 1
- 238000012916 structural analysis Methods 0.000 description 1
- 230000004083 survival effect Effects 0.000 description 1
- 238000002560 therapeutic procedure Methods 0.000 description 1
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Abstract
The utility model relates to a multi-mode galactophore blood oxygen function imaging system which comprises a light source, a blood oxygen detector, a three-operator detector, a signal collecting unit for blood oxygen and three operators, a computer and a multi-mode analysis and treatment system. The multi-mode galactophore blood oxygen function imaging system is characterized in that two output ends of the blood oxygen detector are respectively connected with the input end of a blood oxygen image collecting card in the signal collecting unit for blood oxygen and three operators through video cables; the output end of the three-operator detector is connected with the input end of the three-operator image collecting card in the signal collecting unit for blood oxygen and three operators through video cables; the three output ends of the signal collecting unit for blood oxygen and three operators is respectively connected with the computer and the multi-mode analysis and treatment system. The multi-mode galactophore blood oxygen function imaging system combines the morphological diagnosis and the functional diagnosis into a whole, and provides comprehensive multi-mode information for the diagnosis of a doctor.
Description
Technical field
This utility model relates to a kind of medical imaging device that integrates functional image and morphology image, particularly relates to a kind of multi-modal mammary gland blood-oxygen functional imaging system that can be applicable to diagnosis of breast disease.
Background technology
Breast carcinoma is one of common malignant tumor of women, clinical empirical summary in the last thirty years shows: patient with breast cancer's mortality rate does not decrease because of any change of Therapeutic Method, its main cause is that the clinical patients majority is middle and advanced stage, all makes the treatment failure because of hematogenous metastasis.The early diagnosis of breast carcinoma and early treatment improve the important of breast carcinoma survival rate and valid approach, and therefore, studying at home and abroad to the imaging diagnosis method of breast carcinoma, medical circle is subjected to paying attention to widely.
Existing conventional breast image diagnostic device or be the morphology image documentation equipment, or be the function assessment image documentation equipment, it is less and single to make that so a kind of equipment offers the quantity of information of diagnosis, and its result causes accuracy rate of diagnosis not high.If a kind of imaging diagnosis equipment is integrated in one morphology and function assessment diagnostic method, form a kind of multi-modal imaging diagnosis equipment, will be for diagnosis provide comprehensive multi-modal information, this also is a kind of development trend of diagnostic image equipment in recent years.
Summary of the invention
Order of the present utility model is in order to overcome the shortcoming of current conventional breast image diagnostic device pattern single (morphology or function assessment), and a kind of multi-modal mammary gland blood-oxygen functional imaging system that morphology and function assessment are diagnosed that integrates is provided.
For achieving the above object, technical solution adopted in the utility model is:
A kind of multi-modal mammary gland blood-oxygen functional imaging system, comprise: light source, the blood oxygen probe, three operator detectors, blood oxygen and three ways of calculating subsignal collecting unit, computer and multi-modal analysis process system, it is characterized in that: in the blood oxygen probe two outfans through video line respectively with blood oxygen and three ways of calculating subsignal collecting unit in oxigram link to each other as two inputs of capture card, the input of the three ways of calculating subimage capture card of the outfan of three operator detectors in video line and blood oxygen and three ways of calculating subsignal collecting unit links to each other, and three outfans of blood oxygen and three ways of calculating subsignal collecting unit link to each other with computer and multi-modal analysis process system respectively.
Described computer and multi-modal analysis process system, comprise computer, mammary gland blood-oxygen is analyzed and processing unit, three operator analysis and processing units, the multifunctional image display unit, the oxigram of blood oxygen and three ways of calculating subsignal collecting unit links to each other with two inputs of mammary gland blood-oxygen analysis and processing unit respectively as two outfans of capture card, the outfan of the three ways of calculating subimage capture card of blood oxygen and three ways of calculating subsignal collecting unit links to each other with the input of three operator analyses and processing unit, computer respectively with mammary gland blood-oxygen analysis and processing unit, the outfan of three operator analyses and processing unit links to each other, computer links to each other with the input of multifunctional image display unit, the multifunctional image display unit is made of two video cards and double-display screen, and double-display screen is respectively applied for and shows blood-oxygen functional image and three ways of calculating subimage.
Described light source is the visible～near-infrared light source that sends the 500nm-1500nm continuous spectrum, be divided into two light paths behind visible～near-infrared continuous light transmission mammary gland that light source sends: function assessment information light path and morphologic information light path enter blood oxygen probe and three operator detectors respectively.
Described blood oxygen probe is made up of two optical filters of putting side by side, two lens of putting side by side and two photographic head of putting side by side, two optical filters of putting side by side place the dead ahead of two lens of putting side by side respectively, two lens of putting side by side place the dead ahead of two photographic head of putting side by side respectively, and the transparent wavelength range of two optical filters is respectively λ
1=600nm-800nm, λ
2=810nm-1000nm, the receiver wavelength range of two photographic head is visible～near-infrared continuous spectrum of 500nm-1500nm, be used for the difference receiving function and learn the optical signal transmissive that the information light path sees through two optical filters, and convert optical signal transmissive to signal of telecommunication output.
Described three operator detectors are made up of lens and a photographic head, the receiver wavelength range of photographic head is visible～near-infrared continuous spectrum of 500nm-1500nm, be used to receive the optical signal transmissive of morphologic information light path, and convert optical signal transmissive to signal of telecommunication output.
Described blood oxygen and three ways of calculating subsignal collecting unit are made up of two image pick-up cards, one has two video inputs mouths for oxigram as capture card, convert the signal of telecommunication of two photographic head outputs in the blood oxygen probe to digital quantity from analog quantity respectively, be input to mammary gland blood-oxygen analysis and processing unit again, mammary gland blood-oxygen analysis and processing unit application mammary tissue blood oxygen cubage formula are imported oxigram as capture card digital quantity analyzes and processing obtains the mammary tissue blood oxygen function data; Another has a video inputs mouth for three ways of calculating subimage capture card, convert the signal of telecommunication of photographic head output in the three operator detectors to digital quantity from analog quantity, be input to three operator analysis and processing units again, the digital quantity of three ways of calculating subimage capture card input analyzed and processing obtains three kinds of character image datas by three ways of calculating subalgorithm; Three kinds of character image datas that the multifunctional image display unit obtains mammary gland blood-oxygen analysis and processing unit after through the mammary tissue blood oxygen function data that obtain after calculating and three operator analyses and processing unit processes change into image mode and are presented on the display screen, are used for doctor's analysis and diagnosis.
Also comprise system control unit, The Cloud Terrace camera lens control unit and function key operating unit, system control unit links to each other with computer, The Cloud Terrace camera lens control unit, function key operating unit respectively, and The Cloud Terrace camera lens control unit links to each other with the The Cloud Terrace of fix blood oxygen probe with three operator detectors.Computer is regulated control The Cloud Terrace camera lens control unit and function key operating unit by system control unit, The Cloud Terrace camera lens control unit is used to control The Cloud Terrace and drives the rotation up and down of the photographic head in blood oxygen probe, the three operator detectors and the focusing and the aperture adjusting of cam lens, and the function key operating unit is provided with on and off switch, cradle head control button and camera adjusting button.
Also comprise picture archiving and communication unit, report generation and print unit, data base administration and retrieval unit, picture archiving links to each other with computer respectively with the input of retrieval unit with print unit, data base administration with communication unit, report generation.Leave mammary tissue blood oxygen function data and three kinds of character image datas in data base administration and retrieval unit and can realize the telecommunication and the transmission of blood-oxygen functional image and three kinds of characteristic images by computer, also can generate and print unit print mammary tissue blood oxygen function data and three kinds of character image datas by report by picture archiving and communication unit.
The mammary tissue blood oxygen function imaging process is carried out according to the following steps: it is visible～near infrared light of 500nm-1500nm and to tested side mammary gland (referring to a doubtful ill mammary gland in two mammary gland of human body) transmission that (1), light source send continuous wavelength, and it is λ through wavelength respectively that the function assessment information light path in its transillumination is divided two-way again
1=600nm-800nm, λ
2The optical filter of=810nm-1000nm filters, again through after the lens focus respectively the photographic head by separately be imaged on the CCD plane; Then, be sent to respectively in blood oxygen and the three ways of calculating subsignal collecting unit through video line by the analog video output port of separately photographic head and have the input of the oxigram of two video inputs mouths as capture card, become digital quantity by analog-to-digital conversion again and be input to mammary gland blood-oxygen analysis and processing unit as capture card by oxigram, carry out date processing machine and export two width of cloth digitized galactophore images that the multifunctional image display unit obtains tested side mammary gland to as calculated by mammary gland blood-oxygen analysis and processing unit; (2), (1) to reference side mammary gland (referring in two mammary gland of human body another mammary gland with respect to tested side mammary gland) transmission, obtains two width of cloth digitized galactophore images with reference to side mammary gland with visible～near infrared light (500nm one 1500nm) of continuous wavelength set by step; (3), tested side that step (1), (2) are obtained and the blood that obtains tested side mammary gland with reference to side mammary gland totally after 2. 1. four width of cloth images calculated through computing formula by mammary gland blood-oxygen analysis and processing unit respectively contain spirogram and oxygen content figure.
Blood content:
①
Oxygen content:
②
In the formula:
I
b(x, y) the tested side mammary gland blood of expression contains (x, the blood content of y) locating on the spirogram;
I
o(x, y) (x, the oxygen content of y) locating on the tested side mammary gland oxygen content figure of expression;
H
1(x, y) expression visible～tested side mammary gland of transmission of near infra red light and be λ by wavelength
1Optical filter after corresponding to (x y) locates the light intensity that CCD detects on the infrared scan image;
H
2(x, y) expression visible～tested side mammary gland of transmission of near infra red light and be λ by wavelength
2Optical filter after corresponding to (x y) locates the light intensity that CCD detects on the infrared scan image;
J
1(x, y) represent as seen～transmission of near infra red light is λ with reference to side mammary gland and by wavelength
1Optical filter after corresponding to (x y) locates the light intensity that CCD detects on the infrared scan image;
J
2(x, y) represent as seen～transmission of near infra red light is λ with reference to side mammary gland and by wavelength
2Optical filter after corresponding to (x y) locates the light intensity that CCD detects on the infrared scan image.
Mammary gland three operator imaging analysis and processing procedure are carried out according to the following steps: (1), to send continuous wavelength by light source be visible～near infrared light of 500nm-1500nm and to the mammary gland transmission, transillumination in its morphologic information light path is received by three operator detectors, by converting optical signal to the signal of telecommunication by CCD again after the lens focus in the photographic head; Then, be sent to the input of three ways of calculating subimage capture card in blood oxygen and the three ways of calculating subsignal collecting unit by the analog video output port of photographic head through video line, analog electrical signal is changed into digital quantity and be input to three operator analysis and processing units, machine is obtained the transillumination original image of mammary gland by the multifunctional image display unit as calculated; (2), by three operator analyses and processing unit original image is carried out three operators respectively and handles and obtain following three kinds of characteristic informations, machine obtains mammary gland three ways of calculating subcharacter image by the multifunctional image display unit as calculated.Three operator function are as follows:
Sobel operator after A, the improvement: image is carried out the edge enhancement process, can extract the organizational structure information in the near-infrared mammary transmission raw video effectively, read and handle grey scale curve such as afterwards resulting, normal breast often shows with the nipple to be the even arc curve at center; When organizational structure is unusual, then get muddled etc. grey scale curve;
B, the anisotropy gradient after improving and smoothly mixes operator: the blood vessel of hiding in can original image clear effectively, especially grey shadow zone is subjected to background influence unclear blood vessel clear, and the variation of blood vessel be resolution very, one of the key character of malignant tumor;
C, edge sharpening operator: original image is subjected to the influence of mammary gland inner tissue structural change, background often forms the light gray shadow, and is heavy with the grey shade of diseased region, do not see the edge of diseased region ghost, after the processing of edge sharpening operator, it is crude or smooth that the ghost edge is demonstrated; The edge is not whole, is the feature of malignant change like crab-like, thereby the pernicious sign of the blood vessel of lump periphery can be showed yet.
Description of drawings
Fig. 1 is that multi-modal mammary gland blood-oxygen functional imaging system constitutes block diagram.
Fig. 2 is that tested side mammary gland is through λ
1Transillumination original graph behind the optical filter.
Fig. 3 is that tested side mammary gland is through λ
2Transillumination original graph behind the optical filter.
Fig. 4 is through λ with reference to side mammary gland
1Transillumination original graph behind the optical filter.
Fig. 5 is through λ with reference to side mammary gland
2Transillumination original graph behind the optical filter.
Fig. 6 contains spirogram for the blood of mammary gland.
Fig. 7 is the oxygen content figure of mammary gland.
Fig. 8 is the transillumination original graph of mammary gland.
Fig. 9 is the structural analysis figure that the sobel operator of transillumination original graph after improving of mammary gland handled.
Figure 10 is the anisotropy gradient of transillumination original graph after improving and the blood vessel figure clear that smoothly mixes the operator processing of mammary gland.
Figure 11 is the edge detection graph that the transillumination original graph of mammary gland is handled through the edge sharpening operator.
The specific embodiment
Describe this utility model in detail below in conjunction with accompanying drawing and specific embodiment.
Referring to Fig. 1, a kind of multi-modal mammary gland blood-oxygen functional imaging system, comprise: light source, the blood oxygen probe, three operator detectors, blood oxygen and three ways of calculating subsignal collecting unit, computer and multi-modal analysis process system, it is characterized in that: in the blood oxygen probe two outfans through video line respectively with blood oxygen and three ways of calculating subsignal collecting unit in oxigram link to each other as two inputs of capture card, the input of the three ways of calculating subimage capture card of the outfan of three operator detectors in video line and blood oxygen and three ways of calculating subsignal collecting unit links to each other, and three outfans of blood oxygen and three ways of calculating subsignal collecting unit link to each other with computer and multi-modal analysis process system respectively.
Described computer and multi-modal analysis process system, comprise computer, mammary gland blood-oxygen is analyzed and processing unit, three operator analysis and processing units, the multifunctional image display unit, the oxigram of blood oxygen and three ways of calculating subsignal collecting unit links to each other with two inputs of mammary gland blood-oxygen analysis and processing unit respectively as two outfans of capture card, the outfan of the three ways of calculating subimage capture card of blood oxygen and three ways of calculating subsignal collecting unit links to each other with the input of three operator analyses and processing unit, computer respectively with mammary gland blood-oxygen analysis and processing unit, the outfan of three operator analyses and processing unit links to each other, computer links to each other with the input of multifunctional image display unit, the multifunctional image display unit is made of two video cards and double-display screen, and double-display screen is respectively applied for and shows blood-oxygen functional image and three ways of calculating subimage.
Described light source is the visible～near-infrared light source that sends the 500nm-1500nm continuous spectrum, be divided into two light paths behind visible～near-infrared continuous light transmission mammary gland that light source sends: function assessment information light path and morphologic information light path enter blood oxygen probe and three operator detectors respectively.
Described blood oxygen probe is made up of two optical filters of putting side by side, two lens of putting side by side and two photographic head of putting side by side, two optical filters of putting side by side place the dead ahead of two lens of putting side by side respectively, two lens of putting side by side place the dead ahead of two photographic head of putting side by side respectively, and the transparent wavelength range of two optical filters is respectively λ
1=600nm-800nm, λ
2=810nm-1000nm, the receiver wavelength range of two photographic head is visible～near-infrared continuous spectrum of 500nm-1500nm, be used for the difference receiving function and learn the optical signal transmissive that the information light path sees through two optical filters, and convert optical signal transmissive to signal of telecommunication output.
Described three operator detectors are made up of lens and a photographic head, the receiver wavelength range of photographic head is visible～near-infrared continuous spectrum of 500nm-1500nm, be used to receive the optical signal transmissive of morphologic information light path, and convert optical signal transmissive to signal of telecommunication output.
Described blood oxygen and three ways of calculating subsignal collecting unit are made up of two image pick-up cards, one has two video inputs mouths for oxigram as capture card, convert the signal of telecommunication of two photographic head outputs in the blood oxygen probe to digital quantity from analog quantity respectively, be input to mammary gland blood-oxygen analysis and processing unit again, mammary gland blood-oxygen analysis and processing unit application mammary tissue blood oxygen cubage formula are imported oxigram as capture card digital quantity analyzes and processing obtains the mammary tissue blood oxygen function data; Another has a video inputs mouth for three ways of calculating subimage capture card, convert the signal of telecommunication of photographic head output in the three operator detectors to digital quantity from analog quantity, be input to three operator analysis and processing units again, the digital quantity of three ways of calculating subimage capture card input analyzed and processing obtains three kinds of character image datas by three ways of calculating subalgorithm; Three kinds of character image datas that the multifunctional image display unit obtains mammary gland blood-oxygen analysis and processing unit after through the mammary tissue blood oxygen function data that obtain after calculating and three operator analyses and processing unit processes change into image mode and are presented on the display screen, are used for doctor's analysis and diagnosis.
Also comprise system control unit, The Cloud Terrace camera lens control unit and function key operating unit, system control unit links to each other with computer, The Cloud Terrace camera lens control unit, function key operating unit respectively, and The Cloud Terrace camera lens control unit links to each other with the The Cloud Terrace of fix blood oxygen probe with three operator detectors.Computer is regulated control The Cloud Terrace camera lens control unit and function key operating unit by system control unit, The Cloud Terrace camera lens control unit is used to control The Cloud Terrace and drives the rotation up and down of the photographic head in blood oxygen probe, the three operator detectors and the focusing and the aperture adjusting of cam lens, and the function key operating unit is provided with on and off switch, cradle head control button and camera adjusting button.
Also comprise picture archiving and communication unit, report generation and print unit, data base administration and retrieval unit, picture archiving links to each other with computer respectively with the input of retrieval unit with print unit, data base administration with communication unit, report generation.Leave mammary tissue blood oxygen function data and three kinds of character image datas in data base administration and retrieval unit and can realize the telecommunication and the transmission of blood-oxygen functional image and three kinds of characteristic images by computer, also can generate and print unit print mammary tissue blood oxygen function data and three kinds of character image datas by report by picture archiving and communication unit.
The mammary tissue blood oxygen function imaging process is carried out according to the following steps: it is visible～near infrared light of 500nm-1500nm and to tested side mammary gland (referring to a doubtful ill mammary gland in two mammary gland of human body) transmission that (1), light source send continuous wavelength, and it is λ through wavelength respectively that the function assessment information light path in its transillumination is divided two-way again
1=600nm-800nm, λ
2The optical filter of=810nm-1000nm filters, again through after the lens focus respectively the photographic head by separately be imaged on the CCD plane; Then, be sent to respectively in blood oxygen and the three ways of calculating subsignal collecting unit through video line by the analog video output port of separately photographic head and have the input of the oxigram of two video inputs mouths as capture card, become digital quantity by analog-to-digital conversion again and be input to mammary gland blood-oxygen analysis and processing unit as capture card by oxigram, carry out date processing machine and export two width of cloth digitized galactophore images such as Fig. 2, Fig. 3 that the multifunctional image display unit obtains tested side mammary gland to as calculated by mammary gland blood-oxygen analysis and processing unit; (2), (1) to reference side mammary gland (referring in two mammary gland of human body another mammary gland with respect to tested side mammary gland) transmission, obtains two width of cloth digitized galactophore images such as Fig. 4, Fig. 5 with reference to side mammary gland with visible～near infrared light (500nm one 1500nm) of continuous wavelength set by step; (3), tested side that step (1), (2) are obtained and the blood that obtains tested side mammary gland with reference to side mammary gland totally after 2. 1. four width of cloth images calculated through computing formula by mammary gland blood-oxygen analysis and processing unit respectively contain spirogram such as Fig. 6 and oxygen content figure such as Fig. 7.
Blood content:
①
Oxygen content:
②
In the formula:
I
b(x, y) the tested side mammary gland blood of expression contains (x, the blood content of y) locating on the spirogram;
I
o(x, y) (x, the oxygen content of y) locating on the tested side mammary gland oxygen content figure of expression;
H
1(x, y) expression visible～tested side mammary gland of transmission of near infra red light and be λ by wavelength
1Optical filter after corresponding to (x y) locates the light intensity that CCD detects on the infrared scan image;
H
2(x, y) expression visible～tested side mammary gland of transmission of near infra red light and be λ by wavelength
2Optical filter after corresponding to (x y) locates the light intensity that CCD detects on the infrared scan image;
J
1(x, y) represent as seen～transmission of near infra red light is λ with reference to side mammary gland and by wavelength
1Optical filter after corresponding to (x y) locates the light intensity that CCD detects on the infrared scan image;
J
2(x, y) represent as seen～transmission of near infra red light is λ with reference to side mammary gland and by wavelength
2Optical filter after corresponding to (x y) locates the light intensity that CCD detects on the infrared scan image.
Mammary gland three operator imaging analysis and processing procedure are carried out according to the following steps: (1), to send continuous wavelength by light source be visible～near infrared light of 500nm-1500nm and to the mammary gland transmission, transillumination in its morphologic information light path is received by three operator detectors, by converting optical signal to the signal of telecommunication by CCD again after the lens focus in the photographic head; Then, be sent to the input of three ways of calculating subimage capture card in blood oxygen and the three ways of calculating subsignal collecting unit by the analog video output port of photographic head through video line, analog electrical signal is changed into digital quantity and be input to three operator analysis and processing units, machine is obtained transillumination original image such as Fig. 8 of mammary gland by the multifunctional image display unit as calculated; (2), by three operator analyses and processing unit original image is carried out three operators respectively and handles and obtain following three kinds of characteristics, machine obtains mammary gland three ways of calculating subimage such as Fig. 9, Figure 10, Figure 11 by the multifunctional image display unit as calculated.Three operator function are as follows:
Sobel operator after A, the improvement: image is carried out the edge enhancement process, can extract the organizational structure information in the near-infrared mammary transmission raw video effectively, read and handle grey scale curve such as afterwards resulting, normal breast often shows with the nipple to be the even arc curve at center; When organizational structure is unusual, then get muddled etc. grey scale curve;
B, the anisotropy gradient after improving and smoothly mixes operator: the blood vessel of hiding in can original image clear effectively, especially grey shadow zone is subjected to background influence unclear blood vessel clear, and the variation of blood vessel be resolution very, one of the key character of malignant tumor;
C, edge sharpening operator: original image is subjected to the influence of mammary gland inner tissue structural change, background often forms the light gray shadow, and is heavy with the grey shade of diseased region, do not see the edge of diseased region ghost, after the processing of edge sharpening operator, it is crude or smooth that the ghost edge is demonstrated; The edge is not whole, is the feature of malignant change like crab-like, thereby the pernicious sign of the blood vessel of lump periphery can be showed yet.
Claims (8)
1, a kind of multi-modal mammary gland blood-oxygen functional imaging system, comprise: light source, the blood oxygen probe, three operator detectors, blood oxygen and three ways of calculating subsignal collecting unit, computer and multi-modal analysis process system, it is characterized in that: in the blood oxygen probe two outfans through video line respectively with blood oxygen and three ways of calculating subsignal collecting unit in oxigram link to each other as two inputs of capture card, the input of the three ways of calculating subimage capture card of the outfan of three operator detectors in video line and blood oxygen and three ways of calculating subsignal collecting unit links to each other, and three outfans of blood oxygen and three ways of calculating subsignal collecting unit link to each other with computer and multi-modal analysis process system respectively.
2, multi-modal mammary gland blood-oxygen functional imaging system according to claim 1, it is characterized in that: described computer and multi-modal analysis process system, comprise computer, mammary gland blood-oxygen is analyzed and processing unit, three operator analysis and processing units, the multifunctional image display unit, the oxigram of blood oxygen and three ways of calculating subsignal collecting unit links to each other with two inputs of mammary gland blood-oxygen analysis and processing unit respectively as two outfans of capture card, the outfan of the three ways of calculating subimage capture card of blood oxygen and three ways of calculating subsignal collecting unit links to each other with the input of three operator analyses and processing unit, computer respectively with mammary gland blood-oxygen analysis and processing unit, the outfan of three operator analyses and processing unit links to each other, and computer links to each other with the input of multifunctional image display unit.
3, multi-modal mammary gland blood-oxygen functional imaging system according to claim 1 and 2, it is characterized in that: also comprise system control unit, The Cloud Terrace camera lens control unit and function key operating unit, system control unit links to each other with computer, The Cloud Terrace camera lens control unit, function key operating unit respectively, and The Cloud Terrace camera lens control unit links to each other with the The Cloud Terrace of fix blood oxygen probe with three operator detectors.
4, multi-modal mammary gland blood-oxygen functional imaging system according to claim 1 and 2, it is characterized in that: also comprise picture archiving and communication unit, report generation and print unit, data base administration and retrieval unit, picture archiving links to each other with computer respectively with the input of retrieval unit with print unit, data base administration with communication unit, report generation.
5, multi-modal mammary gland blood-oxygen functional imaging system according to claim 1 is characterized in that: described light source is the visible～near-infrared light source that sends the 500nm-1500nm continuous spectrum.
6, multi-modal mammary gland blood-oxygen functional imaging system according to claim 1, it is characterized in that: described blood oxygen probe is made up of two optical filters of putting side by side, two lens of putting side by side and two photographic head of putting side by side, two optical filters of putting side by side place the dead ahead of two lens of putting side by side respectively, two lens of putting side by side place the dead ahead of two photographic head of putting side by side respectively, and the transparent wavelength range of two optical filters is respectively λ
1=600nm-800nm, λ
2=810nm-1000nm, the receiver wavelength range of two photographic head is visible～near-infrared continuous spectrum of 500nm-1500nm, be used for the difference receiving function and learn the optical signal transmissive that the information light path sees through two optical filters, and convert optical signal transmissive to signal of telecommunication output.
7, multi-modal mammary gland blood-oxygen functional imaging system according to claim 1, it is characterized in that: described three operator detectors are made up of lens and a photographic head, the receiver wavelength range of photographic head is visible～near-infrared continuous spectrum of 500nm-1500nm, be used to receive the optical signal transmissive of morphologic information light path, and convert optical signal transmissive to signal of telecommunication output.
8, multi-modal mammary gland blood-oxygen functional imaging system according to claim 1, it is characterized in that: described blood oxygen and three ways of calculating subsignal collecting unit are made up of two image pick-up cards, one has two video inputs mouths for oxigram as capture card, convert the signal of telecommunication of two photographic head outputs in the blood oxygen probe to digital quantity from analog quantity respectively, be input to mammary gland blood-oxygen analysis and processing unit again; Another has a video inputs mouth for three ways of calculating subimage capture card, and the signal of telecommunication that photographic head in the three operator detectors is exported converts digital quantity to from analog quantity, is input to three operator analysis and processing units again.
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| CNU2008201905129U CN201256969Y (en) | 2008-08-27 | 2008-08-27 | Multi-modality mammary gland blood-oxygen function imagine system |
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| CNU2008201905129U CN201256969Y (en) | 2008-08-27 | 2008-08-27 | Multi-modality mammary gland blood-oxygen function imagine system |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106659406A (en) * | 2014-07-08 | 2017-05-10 | 诺基亚技术有限公司 | An apparatus and method for monitoring biometric parameters using an ambient light collector |
| CN116236164A (en) * | 2022-12-20 | 2023-06-09 | 哈尔滨海鸿基业科技发展有限公司 | Real-time blood transport reconstruction assessment device |
-
2008
- 2008-08-27 CN CNU2008201905129U patent/CN201256969Y/en not_active Expired - Lifetime
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106659406A (en) * | 2014-07-08 | 2017-05-10 | 诺基亚技术有限公司 | An apparatus and method for monitoring biometric parameters using an ambient light collector |
| US10722157B2 (en) | 2014-07-08 | 2020-07-28 | Nokia Technologies Oy | Apparatus and method for monitoring biometric parameters using an ambient light collector |
| CN116236164A (en) * | 2022-12-20 | 2023-06-09 | 哈尔滨海鸿基业科技发展有限公司 | Real-time blood transport reconstruction assessment device |
| CN116236164B (en) * | 2022-12-20 | 2023-12-08 | 哈尔滨海鸿基业科技发展有限公司 | Real-time blood transport reconstruction assessment device |
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Address after: 430074 hi tech medical apparatus Park, No. 818, hi tech Avenue, East Lake New Technology Development Zone, Hubei, Wuhan Province, B8-A4, B4, C4 Patentee after: Wuhan sea digital medical Polytron Technologies Inc Address before: 430074 hi tech medical apparatus Park, No. 818, hi tech Avenue, East Lake hi tech Development Zone, Hubei, Wuhan, B8-ABC4 Patentee before: Wuhan E-Sea Digital Engineering Co., Ltd. |
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