CN201194952Y - Jack-in inside and outside wall dual structure polytetrafluoroethylene artificial bile duct - Google Patents
Jack-in inside and outside wall dual structure polytetrafluoroethylene artificial bile duct Download PDFInfo
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- CN201194952Y CN201194952Y CNU2008200554290U CN200820055429U CN201194952Y CN 201194952 Y CN201194952 Y CN 201194952Y CN U2008200554290 U CNU2008200554290 U CN U2008200554290U CN 200820055429 U CN200820055429 U CN 200820055429U CN 201194952 Y CN201194952 Y CN 201194952Y
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- dual structure
- outside wall
- wall dual
- choledochus
- plug
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Abstract
The utility model relates to a plug-type inner-outer wall dual structure polyfluortetraethylene artificial choledochus which is a pipe prepared by the compounding of two layers of polymer materials and adopts an inner-outer wall dual structure polyfluortetraethylene tube as the inner material, and chemical fibers are knitted on the surface of the inner-outer wall dual structure polyfluortetraethylene tube by the knitting technology to form the outer material. The artificial choledochus has good biocompatibility, clinical application convenience, long-term durability and better mechanical strength, and is suitable for being used as the choledochus substitute during the plug-type choledochus suturing operation.
Description
Technical field
This utility model belongs to the artificial choledochus field, particularly relates to a kind of plug-in type inside and outside wall dual structure politef artificial choledochus.
Background technology
Along with the development of medical macromolecular materials is upgraded, clinical biological tissue succedaneum has progressed into clinical practice.Compare with technology such as artificial blood vessel, artificial sticking patch, artificial joint, cardiac valve, artificial choledochus research obviously lags behind, and does not have sophisticated bile duct succedaneum to enter clinical practice as yet.In treatments such as tumor of bile duct, bile duct injury, congenital malformation and liver transplantation, press for a kind of bile duct substitute.The appearance of artificial choledochus will produce a kind of brand-new low invasive procedures mode, provide Therapeutic Method easily to the biliary tract treatment that increases day by day.
Extrahepatic biliary passages is unique path that bile is assigned, and it damages and blocks all directly influences liver function.Biliary tract surgery is often because of tumor, inborn variation, liver transplantation, multiple complicated factor such as bile duct injury need carry out the reparation and the reconstruction of extrahepatic bile ducts, that the most frequently used in the past is cholangio-jejunostomy [Leonardi MI, Ataide EC, Boin IF, et al.Role ofcholedochojejunostomy in liver transplantation.Transplant Proc, 2005,37 (2): 1126-1128], but because of it is not a normal physiological routes, normal retrograde infection [the Li Cheng that takes place, grandson is equipped with. the progress of antidromicity biliary tract infection behind the bile duct jejunum Roux-en-Y anastomosis. and international surgery's magazine, 2006,133 (2): 90-93], using substitute reconstruction extrahepatic biliary passages is the effective way [Zheng Jianwei that makes challenge trend advantages of simple, Zou Shengquan. artificial choledochus research. Chinese medicine engineering, 2005,13 (4): 385-387].Clinically press for a kind of safe in utilization, easy, practical bile duct substitution material.
At present the artificial choledochus materials used of development be single macromolecular material [yellow Hua Xin, Wang Chen, Pei Fangjun etc. the real silk artificial gall duct substitutes choledoch-experimentation. Lanzhou medical college journal, 1999,20 (1): 36-38; Xu Jianheng, Guo Guanghua, Zhang Jin etc. the making of polyurethane bile duct prosthese. practical medical journal, 2000,16 (2): 104-105; Zhou Shouli etc. biliary tract Y type support and novel implantation device (CN 2899738)].It is artificial choledochus that human polyurethane (medical grade EU thermoplastic elastomer (TPE) TPE-80B) material is arranged, it has wearability, elasticity and the bile compatibility [Xu Jianheng preferably evidence, Guo Guanghua, Zhang Jin etc. the making of polyurethane bile duct prosthese. practical medical journal, 2000,16 (2): 104-105; Zhang Jie, Li Dong, Li Jianning. the tubulose expanded PTFE is used for the animal experiment study of tissue engineering bracket material. Chinese aesthetic medicine, 2004,13 (6): 650-651].But the coefficient of friction of polyurethane surface is bigger, and the little condition of bile flow resistance is difficult to meet the demands.As a rule, the macromolecule soft material exists cholestasis, leakage problems, and hard material is not easy to sew up.The artificial choledochus form of developing at present mainly contains simple straight pipe type structure [yellow Hua Xin, Wang Chen, Pei Fangjun etc. the real silk artificial gall duct substitutes choledoch-experimentation. Lanzhou medical college journal, 1999,20 (1): 36-38] and gasbag-type bile duct prosthese [Xu Jianheng, bladder-type artificial choledochus (CN2242677)] two classes: simple straight pipe type bile duct can recover the biliary tract seriality, but its shortcoming is cholestasis obstruction, a retrograde infection in the short time; The research of gasbag-type bile duct prosthese can solve the cholestasis problem, but designs loaded down with trivial detailsly, lacks value for clinical application.Therefore there do not have artificial choledochus really to be applied to as yet at present to be clinical.
Recently, people such as Yang Qing [Yang Qing, the highland haze is refined etc. a kind of is the artificial choledochus and preparation method thereof (CN declare in) of raw material with the macromolecular material] declared a patent that adopts teflon hose to prepare artificial choledochus.This patent adopts coefficient of friction less, little and can the corrosive teflon hose of anti-bile be the artificial choledochus inner layer material with water contact angle, to reduce the flow resistance of bile in pipeline; Chemical fibre with higher-strength is used for forming flexible network structure at the teflon hose outer braid, to improve the pipeline tensile strength and the operation stitching demand is provided; Nontoxic, be used to be coated in shape and the intensity of artificial choledochus surface with the good silicone rubber of biocompatible to guarantee compound bile duct.But be not suitable for carrying out plug-in type bile duct suture operation.
Polytetrafluoroethylmaterial material can be used for artificial blood vessel, artificial lung, artificial valve, artificial ear, facial plasty [K L Vidur. medical macromolecular materials, international weaving Leader, 2005,2:75-78 through experiment confirm; Huang Jinghuan, Ding Jiandong. biological medical polymer material and modern medicine. Chinese medical apparatus information, 2004,10 (4): 1-5], its histocompatibility fully confirmed, but at present domesticly still do not have patent report and adopt inside and outside wall dual structure teflon hose to prepare artificial choledochus.
Summary of the invention
The purpose of this utility model provides a kind of plug-in type inside and outside wall dual structure politef artificial choledochus, overcomes the deficiency of existing bile duct succedaneum material.By being main material, adopt two-layer composite technology to prepare artificial choledochus with inside and outside wall dual structure teflon hose.This artificial choledochus possesses good biocompatibility, clinical practice convenience, time durability and better mechanical strength, is applicable to the bile duct substitute that carries out plug-in type bile duct suture operation.
Plug-in type inside and outside wall dual structure politef artificial choledochus of the present utility model, be to adopt the compound tube that is prepared from of two-layer macromolecular material, with inside and outside wall dual structure teflon hose is inner layer material, and chemical fibre is woven in inside and outside wall dual structure teflon hose surface with knitting and forms cladding material.
The interior wall construction of described inside and outside wall dual structure teflon hose is fine and close polytetrafluoroethylene floor, outer wall construction is loose porous polytetrafluoroethylene floor, two-port is the broadening formation structure, big mouthful of diameter of horn mouth is 4～19 millimeters, the osculum diameter is 4～15 millimeters, flexible pipe middle part wall thickness is 0.05～2 millimeter, and length is 50～150 millimeters;
The described raw materials of chemical fibres are polyethylene terephthalate (PET) fiber, polybutylene terephthalate (PBT) fiber, polypropylene (PP) fiber, polyamide 6 (PA6) fiber, polyamide 66 (PA66) fiber or polyethylene (PE) fiber, these chemical fibre fibers forms can be monofilament or multifilament, the multifilament radical is 2～100, the fiber number of monofilament is 5～50dtex, and the fiber number of monofilament is 1～10dtex in the multifilament.
The beneficial effects of the utility model:
This utility model is a kind of double-layer artificial bile duct that adopts the composite technology preparation.Internal layer adopts inside and outside wall dual structure teflon hose, its interior wall construction is fine and close polytetrafluoroethylene floor, has liquid-impermeable, smooth surface, coefficient of friction is less, little with water contact angle, the flow resistance of bile in pipeline is little and can the corrosive advantage of anti-bile; Outer wall construction is loose porous polytetrafluoroethylene floor, can improve the compatibility with tissue.The flexible network structure that the skin of artificial choledochus adopts the fibrage of high strength chemistry to form is to improve the pipeline tensile strength and the operation stitching demand is provided.
Adopt the intensity and the flexibility of the inside and outside wall dual structure teflon hose may command artificial choledochus of different inside and outside wall thickness and Maturity; The flexible pipe two-port is the broadening formation structure, can avoid being created in bile duct and carry out can causing the sedimentary dead angle of bile when plug-in type is sewed up.Factors such as kind, DANFU filate formula, fiber number and weaving manner by regulating chemical fibre are the flexibility and the tissue apposition structure of adjustable artificial choledochus also.
The histocompatibility of polytetrafluoroethylmaterial material is fully confirmed, and the two-layer composite material preparation process of artificial choledochus also provides good clinical manipulation performance, therefore this utility model has safe, simple in structure, convenience operation than the imagination of existing artificial choledochus, can satisfy the bile duct substitute demand as plug-in type bile duct suture operation.
Description of drawings
Fig. 1 is a plug-in type inside and outside wall dual structure teflon hose cross-sectional schematic, and outer wall is the porous Teflon layer, and inwall is fine and close polytetrafluoroethylene floor;
Fig. 2 is a plug-in type inside and outside wall dual structure politef artificial choledochus schematic appearance, and the centre is the chemical fibre mesh grid.
The specific embodiment
Below in conjunction with specific embodiment, further set forth this utility model.Should be understood that these embodiment only to be used to this utility model is described and be not used in the restriction scope of the present utility model.Should be understood that in addition those skilled in the art can make various changes or modifications this utility model after the content of having read this utility model instruction, these equivalent form of values fall within the application's appended claims institute restricted portion equally.
Get an inside and outside wall dual structure teflon hose, 1 big mouthful of diameter of horn mouth is 7 millimeters, and the osculum diameter is 6 millimeters, and length is 60 millimeters.Select polyethylene terephthalate (PET) multifilament fiber for use, specification is 55dtex/28f.With inside and outside wall dual structure teflon hose is the core pipe, and in the flexible pipe outside, the yarn radical is 6 to the employing knitting type with the PET fibre-coated.To this product pack, after sterilization handles, the preparation of artificial choledochus finishes.This material is sewed up the artificial choledochus substitute applicable to the plug-in type than ting model.
Embodiment 2
Get an inside and outside wall dual structure teflon hose, 1 big mouthful of diameter of horn mouth is 10 millimeters, and the osculum diameter is 9 millimeters, and length is 90 millimeters.Select polyamide 6 (PA6) monfil for use, specification is 20dtex.With inside and outside wall dual structure teflon hose is the core pipe, and in the flexible pipe outside, the yarn radical is 12 to the employing knitting type with the PA6 fibre-coated.To this product pack, after sterilization handles, the preparation of artificial choledochus finishes.This material is sewed up the artificial choledochus substitute applicable to the plug-in type of medium model.
Embodiment 3
Get an inside and outside wall dual structure teflon hose, 1 big mouthful of diameter of horn mouth is 13 millimeters, and the osculum diameter is 12 millimeters, and length is 120 millimeters.Select polyamide 66 (PA66) multifilament fiber for use, specification is 165dtex/48f.With inside and outside wall dual structure teflon hose is the core pipe, and in the flexible pipe outside, the yarn radical is 36 to the employing knitting type with the PA66 fibre-coated.To this product pack, after sterilization handles, the preparation of artificial choledochus finishes.This material is sewed up the artificial choledochus substitute applicable to the plug-in type of big model.
Claims (5)
1. plug-in type inside and outside wall dual structure politef artificial choledochus, it is characterized in that: this artificial choledochus is to adopt the compound tube that is prepared from of two-layer macromolecular material, with inside and outside wall dual structure teflon hose is inner layer material, and chemical fibre is woven in inside and outside wall dual structure teflon hose surface with knitting and forms cladding material.
2. plug-in type inside and outside wall dual structure politef artificial choledochus according to claim 1, it is characterized in that: the interior wall construction of described inside and outside wall dual structure teflon hose is fine and close polytetrafluoroethylene floor, and outer wall construction is loose porous polytetrafluoroethylene floor.
3. plug-in type inside and outside wall dual structure politef artificial choledochus according to claim 1 and 2, it is characterized in that: the two-port of described inside and outside wall dual structure teflon hose is broadening formation structure (1), the big mouthful diameter of horn mouth (1) is 4～19 millimeters, the osculum diameter is 4～15 millimeters, flexible pipe middle part wall thickness is 0.05～2 millimeter, and length is 50～150 millimeters.
4. plug-in type inside and outside wall dual structure politef artificial choledochus according to claim 1, it is characterized in that: described chemical fibre is dacron fibre, poly fiber, polypropylene fibre, daiamid-6 fiber, polyamide 66 fiber or polyethylene fibre.
5. according to claim 1 or 4 described plug-in type inside and outside wall dual structure politef artificial choledochus, it is characterized in that: the fibers form of described chemical fibre is monofilament or multifilament, the multifilament radical is 2～100, the fiber number of monofilament is 5～50dtex, and the fiber number of monofilament is 1～10dtex in the multifilament.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNU2008200554290U CN201194952Y (en) | 2008-02-04 | 2008-02-04 | Jack-in inside and outside wall dual structure polytetrafluoroethylene artificial bile duct |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNU2008200554290U CN201194952Y (en) | 2008-02-04 | 2008-02-04 | Jack-in inside and outside wall dual structure polytetrafluoroethylene artificial bile duct |
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| Publication Number | Publication Date |
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| CN201194952Y true CN201194952Y (en) | 2009-02-18 |
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| CNU2008200554290U Expired - Fee Related CN201194952Y (en) | 2008-02-04 | 2008-02-04 | Jack-in inside and outside wall dual structure polytetrafluoroethylene artificial bile duct |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102641160A (en) * | 2012-04-24 | 2012-08-22 | 浙江大学 | Artificial bile duct bionic stent with double-layered compound structure and preparation method of artificial bile duct bionic stent |
| CN103841929A (en) * | 2011-09-28 | 2014-06-04 | 伊西康公司 | Negative pressure intestinal anastomosis protection devices |
-
2008
- 2008-02-04 CN CNU2008200554290U patent/CN201194952Y/en not_active Expired - Fee Related
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103841929A (en) * | 2011-09-28 | 2014-06-04 | 伊西康公司 | Negative pressure intestinal anastomosis protection devices |
| CN103841929B (en) * | 2011-09-28 | 2016-05-04 | 伊西康公司 | Negative pressure entero-anastomosis protection apparatus |
| CN102641160A (en) * | 2012-04-24 | 2012-08-22 | 浙江大学 | Artificial bile duct bionic stent with double-layered compound structure and preparation method of artificial bile duct bionic stent |
| CN102641160B (en) * | 2012-04-24 | 2014-12-24 | 浙江大学 | Artificial bile duct bionic stent with double-layered compound structure and preparation method of artificial bile duct bionic stent |
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| Date | Code | Title | Description |
|---|---|---|---|
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20090218 Termination date: 20170204 |
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| CF01 | Termination of patent right due to non-payment of annual fee |