CN201107313Y - Liquid sampling shear valve - Google Patents
Liquid sampling shear valve Download PDFInfo
- Publication number
- CN201107313Y CN201107313Y CNU2007201145751U CN200720114575U CN201107313Y CN 201107313 Y CN201107313 Y CN 201107313Y CN U2007201145751 U CNU2007201145751 U CN U2007201145751U CN 200720114575 U CN200720114575 U CN 200720114575U CN 201107313 Y CN201107313 Y CN 201107313Y
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- Prior art keywords
- sampling
- valve plate
- blood
- microcavity
- constant volume
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Abstract
The utility model relates to a liquid sampling shearing valve which comprises a fixed valve plate, a movable valve plate, and a sample injection and sampling induction duct. The liquid sampling shearing valve is characterized in that the fixed valve plate is provided with two fixed capacity microcavities, and the fixed valve plate is provided with two corresponding guiding grooves, the two fixed capacity microcavities are switched between the two guiding grooves which are connected with the sample injection and sampling induction duct. The liquid sampling shearing valve effectively realizes the measured sampling for micro liquid, in particular to ultramicro-liquid, effectively solves the duct blockage problem, can realize the once dilution for a blood sample, improves the running speed of the system, lowers the dosage of diluents, and improves the degree of accuracy and the repetitiveness of measure; in addition, by combining with a quantitative duct and a fixed capacity type cavity, the liquid sampling shearing valve can realize disposable measure and sampling of once multi-magnitude capacity blood, the designed structure is simple, the manufacture cost of the components and the process requirements for processing and assembling the components are lowered.
Description
Technical field
The utility model relates to a kind of metering and sampler of liquid, relates in particular to the device that the cellanalyzer blood-pressure meters is measured sample.
Background technology
The liquid sampling shear valve is usually used in liquid (comprising blood, reagent etc.) the metering sampling of some exact instrument, and cellanalyzer blood sampling shear valve is most typical a kind of structure in the prior art.
Sampling shear valve (claim dividing a blood valve in cellanalyzer again) is the device that a kind of blood-pressure meters of generally adopting in the Medical Instruments is measured sample, common structure is made up of two or three coaxial valve blocks that are installed on the valve shaft, by rotating a slice or two valve blocks wherein, utilize the metering sampling (distribution) of the combination realization of pipeline to blood.The sampling shear valve of being made up of two valve blocks generally is the quantitative pipeline that the blood volume metering is set on fixed valve plate (or moving valve plate) at present, realizes the metering sampling of blood by the pipeline of intercepting measured length (constant volume); Perhaps take to go up making constant volume die cavity (is typical constant volume die cavity as 3,3 of Fig. 1 '), the metering of blood is taken a sample by the realization that is provided with of constant volume die cavity at fixed valve plate (or moving valve plate).Though existing two-piece type sampling shear valve structure is simple relatively, the transmission operation realizes that than being easier to constant volume measurement is easy to conversion,, the problem of the maximum that existing this structure exists is to be difficult to realize the metering of the blood of micro-volume is taken a sample.And in many instances, the metering of the blood of micro-volume sampling for next step operational sequence, shows very important again.For example, the erythrocytic counting of blood cell analysis instrument, its hemodilution reaches more than tens thousand of times, and the metering of micro-blood sample sampling can avoid adopting the secondary or the method for dilution repeatedly, has simplified operation steps, and has significantly reduced the consumption of dilution.
The sampling shear valve of existing three-chip type structure, to a certain extent, overcome two-piece type sampling shear valve and be difficult to realize defective the metering sampling of the blood of micro-volume, it is to realize the metering of blood volume is taken a sample by the size that a series of through holes are set on middle valve block, and, can realize metering sampling to the blood of micro-volume by size to middle valve block thickness, aperture.But to the metering sampling of the blood of ultramicron volume (as 0.1ul and following), the sampling shear valve of three-chip type structure also is difficult to accomplish.The one, because the thickness of middle valve block is subjected to the influence (valve block must have certain thickness) of its structure, that can not do is thin excessively; The 2nd, if the aperture is too small, then when sample introduction, sampling, flushing, can strengthen the resistance of ducting because blood will pass through this small-bore, influence the travelling speed of system, very easily stop up, even the cross pollution of generation blood.For example, if when getting moving valve plate thickness and being 1 millimeter, accomplish the sampling of 0.1ul, the sectional area in its hole can only have 0.1 square millimeter, and such sectional area is sizable to the resistance of blood.
Summary of the invention
The purpose of this utility model is to overcome the above-mentioned defective of prior art, and a kind of sampling shear valve that can measure sampling to the blood of ultramicron volume (as 0.1ul and following) is provided.
Sampling shear valve described in the utility model is the two-piece type structure, fixed valve plate is coaxial with moving valve plate, fixed valve plate is fixed by stationary installation, pass through gearing by stepper motor, drive moving valve plate and do spacing reciprocal rotation, it is characterized in that on moving valve plate, being provided with constant volume microcavity (as 1 of Fig. 1, below also be called for short microcavity), and on fixed valve plate, two guiding grooves (claiming one group of guiding groove again, as 2,2 of Fig. 2 ') and the introducing pipeline that advances, takes a sample that links to each other therewith are set with the corresponding position of constant volume microcavity.By the combination of constant volume microcavity and guiding groove, and advance, take a sample and introduce pipeline, finish the metering sampling of the blood of ultramicron volume.
The utility model is got a constant volume microcavity and is described with corresponding two guiding grooves, is in order to describe the utility model clearly, simply.The utility model can be established a plurality of constant volume microcavitys as required and become many groups guiding groove of one group to make up with two guiding grooves, and introduces pipeline together with corresponding advancing, take a sample, and finishes the metering sampling of the blood of ultramicron volume.
Described in the utility model the constant volume microcavity being set on moving valve plate, and corresponding guiding groove is set on fixed valve plate, is a kind of embodiment.The utility model also can be that the constant volume microcavity is set on fixed valve plate, and the corresponding guiding groove that on moving valve plate, is provided with.This just depends on it is in the enterprising sample of advancing of moving valve plate direction, sampling, still in the enterprising sample of advancing of fixed valve plate direction, sampling, just, advances, takes a sample to introduce pipeline and be arranged on the fixed valve plate, also is arranged on the moving valve plate.And the constant volume microcavity is set on moving valve plate, and corresponding guiding groove is set on fixed valve plate, can avoid introducing the rotation of pipeline, be preferred version of the present utility model.
Principle of work of the present utility model is as described below, and accompanying drawing 5, accompanying drawing 6 are fundamental diagram of the present utility model.
When the microcavity on the moving valve plate A 1 go to fixed valve plate B on 2 pairs of guiding grooves seasonable, blood enters guiding groove 2 by a direction through introducing pipeline, by guiding groove 2, blood is full of microcavity 1; Moving valve plate A rotates, microcavity 1 go to guiding groove 2 ', at this moment, blood flow volume in the microcavity 1 is the blood flow volume that needs metering, sampling, can carry out sampling operation to the blood in the microcavity 1, afterwards, can by the c direction by introduce pipeline to guiding groove 2 ', microcavity 1 cleans, meanwhile, can inject cleaning fluid, introducing pipeline, guiding groove 2 are cleaned by the b direction.Again, moving valve plate A is toward back rotation, the microcavity on the moving valve plate A 1 gone to corresponding with guiding groove 2 on the fixed valve plate B, finishes the metering sampling process of a blood.
Above process is back and forth carried out, and can carry out continuous blood-pressure meters and measure sample.
A described in the utility model, b, c direction, the convenience in the narration just, blood sample introduction, the flushing of introducing pipeline (guiding groove, microcavity), the sampling direction of blood can be according to the different incoming end directions of introducing pipeline, and set.
Described in the utility model blood in the microcavity 1 is intercepted, can inject quantitative dilution and finish by introducing pipeline.Like this, can finish sampling, dilution and the blending process of micro blood once, also simultaneously introducing pipeline, guiding groove, microcavity be washed.
The utility model can be gone up at same moving valve plate (or fixed valve plate) a plurality of microcavitys that vary in size are set, and with corresponding guiding groove combination, realizes the metering sampling of multicapacity micro blood.
The unitized construction of microcavity described in the utility model and guiding groove also can make up with the constant volume die cavity, realizes the metering sampling of multiple order of magnitude capacity blood.The utility model accompanying drawing 3, Fig. 4 are the combination synoptic diagram of microcavity and guide groove and constant volume die cavity.
The unitized construction of microcavity described in the utility model and guiding groove also can make up with quantitative pipeline, realizes the metering sampling of multiple order of magnitude capacity blood.
The unitized construction of microcavity described in the utility model and guiding groove also can make up with quantitative pipeline, constant volume die cavity, realizes the metering sampling of multiple order of magnitude capacity blood.
Sampling shear valve described in the utility model both can be used for the metering sampling of cellanalyzer blood, also can be used for the device that other need carry out the micro-measurement sampling to liquid, for example metering of the various trace reagents in the equipment of chemical industry, sampling; The metering of the various trace reagents in the inspection machine of hospital, sampling or the like.
The utility model has realized effectively to micro liquid (as blood) that owing to adopted the unitized construction of microcavity and guiding groove the particularly metering of ultramicron liquid sampling has solved the line clogging problem simultaneously effectively.And the metering of cellanalyzer blood is taken a sample, can realize once dilution to the blood sample, improved system travelling speed, reduced the dilution consumption of system, the accuracy and the repeatability of system's metering have been improved, and make up with quantitative pipeline, constant volume die cavity, can realize the metering sampling of disposable multiple order of magnitude capacity blood.The utility model project organization is simple, has reduced the cost of manufacture of assembly and the technological requirement of processing and production assembling.
Description of drawings
Fig. 1 is the inner face structural representation of the moving valve plate of an embodiment of the present utility model.1 is a sampling microcavity, 3,3 ' be one group of sampling constant volume die cavity, 11,12,13,14 is confined planes.
Fig. 2 is the inner face structural representation of the utility model with respect to the fixed valve plate of the embodiment of Fig. 1.2,2 ' be with Fig. 1 in sampling microcavity 1 corresponding one group of guiding groove, 4,4 ' be with Fig. 1 in sampling constant volume die cavity 3,3 ' corresponding one group of introducing pipeline.
Fig. 3 is the utility model Fig. 1, moving valve plate inner face shown in Figure 2 and the fixed valve plate inner face skeleton view when being superimposed.1 is the sampling microcavity, and 2 is guiding groove, and be in the two-phase combined location this moment 1 and 2; 3,3 ' be one group of sampling constant volume die cavity, 4 ' for Fig. 1 in 3,3 ' corresponding one group introduce ducted 1 introducing pipeline, 11,12,13,14 is confined planes.
Fig. 4 turns clockwise after the angle for the utility model Fig. 3 moving valve plate, the skeleton view when moving valve plate inner face and fixed valve plate inner face are superimposed, and 1 is the sampling microcavity, 2 ' be guiding groove, at this moment 1 and 2 ' be in the two-phase combined location.3,3 ' be one group of sampling constant volume die cavity, 4,4 ' be with Fig. 1 in 3,3 ' corresponding one group of introducing pipeline, 21,22 is gag lever post.
Principle schematic when Fig. 5 is the utility model sample introduction.Wherein A is a moving valve plate, and B is a fixed valve plate, and 1 is the sampling microcavity, 2,2 ' be and 1 corresponding one group of guiding groove that a is a blood sample introduction direction.
Principle schematic when Fig. 6 takes a sample for the utility model.Wherein A is a moving valve plate, and B is a fixed valve plate, and 1 is a sampling microcavity, 2,2 ' be and 1 corresponding one group of guiding groove, b is for introducing pipeline, guiding groove flushing direction, and c is a dilution flushing direction.
Fig. 7 is a sampling shear valve general assembly synoptic diagram described in the utility model.Wherein A is that moving valve plate, B are that fixed valve plate, C are that valve shaft, D are that stepper motor, E are that fixed head, F are that synchronizing wheel 1, G are for band, H are that locating device, I are synchronizing wheel 2 synchronously.
Fig. 8 is the general assembly synoptic diagram of the embodiment of another form of the utility model.
Embodiment
The utility model will be further described by following examples.
Present embodiment is microcavity and the combination of constant volume die cavity, and Fig. 1, Fig. 2, Fig. 3, Fig. 4, Fig. 7 are the synoptic diagram of present embodiment.
As shown in Figure 7, moving valve plate (A) is by valve shaft (C) and coaxial being superimposed of fixed valve plate (B), by the spring compression on the valve shaft, and be fixed on the fixed head (E) by locating device (H), stepper motor (D) is fixed on the location-plate (E), its synchronizing wheel 1 (F) is connected with synchronizing wheel 2 (I) by being with (G) synchronously, and synchronizing wheel 2 (I) is fixed on the moving valve plate (A).Stepper motor (D) drove band (G), synchronizing wheel 2 (I) synchronously by synchronizing wheel 1 (F), thereby drove moving valve plate (A), did spacing reciprocal rotation.
Setting Fig. 3 is the initial position of present embodiment, confined planes 12 is in the position of backstay 21, confined planes 14 is in the position of backstay 22, when the rotation of moving valve plate A inhour, it is position shown in Figure 4, confined planes 11 goes to the position of backstay 21, and confined planes 13 goes to the position of backstay 22, and moving valve plate is limited with backstay 21, confined planes 13 and backstay 22 by confined planes 11.Vice versa.
As shown in Figure 1, 2, a sampling microcavity (1) is arranged on the moving valve plate, three groups of sampling constant volume die cavities (only mark among the figure one group 3,3 '), and it is corresponding, the introducing pipeline that one group of guiding groove (2,2 ') and guiding groove are arranged on fixed valve plate, and three groups introduced pipeline (only mark among the figure one group 4,4 ').
Skeleton view when Fig. 3, Fig. 4 moving valve plate inner face and fixed valve plate inner face are superimposed, setting Fig. 3 is an initial position, microcavity 1 is corresponding with guiding groove 2, constant volume die cavity 3 ' with introduce pipeline 4 ' corresponding.At this moment, can inject the blood of metering sampling in guiding groove 2 from the introducing pipeline of guiding groove 2, in guiding groove 2 and the microcavity 1, be full of blood simultaneously, congested liquid measure in the microcavity 1 is the blood flow volume that will measure sampling; From introducing pipeline 4 injects the metering sampling to constant volume die cavity 3 blood, in constant volume die cavity 3, also be full of blood, congested liquid measure in constant volume die cavity 3 is the blood flow volume that will measure sampling.
Afterwards, step motor drive synchronizing wheel 1, synchronously band, synchronizing wheel 2 drive moving valve plate by the inhour rotation, at this moment, the blood in the microcavity 1 are separated with guiding groove 2, make microcavity 1 and guiding groove 2 ' corresponding; Equally, with constant volume die cavity 3 ' in blood with introduce pipeline 4 ' separate, make constant volume die cavity 3 ' corresponding with introducing pipeline 4.At this moment, then by guiding groove 2 ' the introducing pipeline inject the quantitatively dilution of (press dilutability), the blood in the microcavity 1 is gone out taking-up; Equally, inject the quantitatively dilution of (press dilutability) by introducing pipeline 4, with constant volume die cavity 3 ' in blood go out taking-up.When carrying out with this process, introducing pipeline, introducing pipeline 4 ' injection cleaning fluid by guiding groove 2, respectively to the introducing pipeline of guiding groove 2, guiding groove 2, and introduce pipeline 4 ' clean (the capacity die cavity 3 of this moment plays connecting pipeline and realizes pipeline 4 ' cleaning).
Afterwards, step motor drive synchronizing wheel 1, synchronously band, synchronizing wheel 2 drive moving valve plate by turning clockwise, and by confined planes on the moving valve plate and the backstay on the fixed valve plate spacing (location), are returned to the initial position of Fig. 3.
Above process is back and forth carried out, and can make metering divide the blood valve to carry out work continuously.
The volume of present embodiment microcavity design is 0.1ul, and the volume of constant volume die cavity 3,4 designs is 20ul.
Fig. 8 is the general assembly synoptic diagram of the utility model present embodiment.
Present embodiment is to take the unitized construction of microcavity and guiding groove and the pipeline combination of constant volume to measure sampling.
And on gearing is provided with, stepper motor is coaxial with moving valve plate, stepper motor is by reducing gear transmission moving valve plate and rely on detent mechanism to make stepper motor do back and forth to rotate, thereby realize the reciprocal rotation of moving valve plate, make up the metering sampling of finishing liquid volume by the unitized construction of microcavity and guiding groove and the pipeline of constant volume.
Claims (5)
1, a kind of liquid sampling shear valve, comprise fixed valve plate, moving valve plate, sample introduction and sampling introducing pipeline, it is characterized in that on moving valve plate, being provided with the constant volume microcavity, and on fixed valve plate, two guiding grooves are set with the corresponding position of constant volume microcavity, the constant volume microcavity switches between two guiding grooves, and guiding groove is introduced pipeline with sample introduction and sampling and is connected.
2, shear valve according to claim 1 is characterized in that being provided with a plurality of constant volume microcavitys on moving valve plate, with the many groups guiding groove combination on the fixed valve plate.
3, shear valve according to claim 1 and 2 is characterized in that being provided with simultaneously constant volume microcavity, constant volume die cavity on moving valve plate.
4, shear valve according to claim 1 and 2 is characterized in that being provided with simultaneously constant volume microcavity, quantitative pipeline on moving valve plate.
5, shear valve according to claim 1 and 2 is characterized in that being provided with simultaneously constant volume microcavity, constant volume die cavity, quantitative pipeline on moving valve plate.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNU2007201145751U CN201107313Y (en) | 2007-09-06 | 2007-09-06 | Liquid sampling shear valve |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNU2007201145751U CN201107313Y (en) | 2007-09-06 | 2007-09-06 | Liquid sampling shear valve |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN201107313Y true CN201107313Y (en) | 2008-08-27 |
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ID=39959122
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNU2007201145751U Expired - Lifetime CN201107313Y (en) | 2007-09-06 | 2007-09-06 | Liquid sampling shear valve |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN201107313Y (en) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103097786A (en) * | 2010-08-18 | 2013-05-08 | G·赫姆 | Shear valve |
| CN104343834A (en) * | 2013-08-05 | 2015-02-11 | 株式会社捷太格特 | Shear valve and torque limiter |
| CN109374798A (en) * | 2018-10-16 | 2019-02-22 | 安徽皖仪科技股份有限公司 | Multi-tube composite sampling valve and its application method |
-
2007
- 2007-09-06 CN CNU2007201145751U patent/CN201107313Y/en not_active Expired - Lifetime
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103097786A (en) * | 2010-08-18 | 2013-05-08 | G·赫姆 | Shear valve |
| CN103097786B (en) * | 2010-08-18 | 2015-07-22 | G·赫姆 | Shear valve |
| CN104343834A (en) * | 2013-08-05 | 2015-02-11 | 株式会社捷太格特 | Shear valve and torque limiter |
| CN109374798A (en) * | 2018-10-16 | 2019-02-22 | 安徽皖仪科技股份有限公司 | Multi-tube composite sampling valve and its application method |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| CX01 | Expiry of patent term |
Granted publication date: 20080827 |
|
| CX01 | Expiry of patent term |