CN201040044Y - Instrument for laboratory animal mouse - Google Patents
Instrument for laboratory animal mouse Download PDFInfo
- Publication number
- CN201040044Y CN201040044Y CNU2006200494286U CN200620049428U CN201040044Y CN 201040044 Y CN201040044 Y CN 201040044Y CN U2006200494286 U CNU2006200494286 U CN U2006200494286U CN 200620049428 U CN200620049428 U CN 200620049428U CN 201040044 Y CN201040044 Y CN 201040044Y
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- model
- velcro
- utility
- mouse
- rat
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Abstract
The utility model relates to an experimental mouse equipment, belonging to the field of the laboratory apparatus. The utility model consists of a X-shaped plaster(1), double sided nylon buckle(2) and nylon buckle(3). The X-shaped plaster is agglutinated by four plasters with each two at the angle of 90 degrees. The double sided nylon buckle and the nylon buckle are sewed on the two ends of the X-shaped plaster respectively. The utility model can make the mouse connect to the spring of the supply drug experimental equipment. The utility model has the advantages of little influence of free motion for mouse, comfortable clothing for mouse, low rate of biting, solid structure, durable tearing and low cost. The rate of maintain in using the experimental equipment of vein spile is improved from 67 percent to more than 95 percent reported by the foreign document and the rate of biting is short of 3 percent. The cost is one in a thousand comparing to the foreign silica gel sheath.
Description
Technical field
The true instrument field of testing of this utility model is specifically related to the laboratory animal Mus and uses equipment, more particularly, relate to a kind of can make experiment with rat be connected on the experimental provision can safety intravenously administrable, and free within the specific limits active laboratory animal equipment.
Background technology
Drugs cause very big harm not only for junkie and family thereof, have more brought the huge social problem.Lot of manpower and material resources has all been dropped into to the drug rehabilitation and the prohibition of drug in countries in the world, but it is little to produce effects, and also fails to find a kind of good drug rehabilitation means up to now.Therefore, disclose addiction mechanism and more seem significant.The most effective animal model of research addiction is the self administration of medication model at present, wherein is most widely used with rat self administration of medication model.Rat self administration of medication model belongs to a kind of of operant conditioned reflex, is specially rats underwent jugular vein intubation, and intubate is drawn from Foramen magnum top through cervical region is subcutaneous, links the micro-injection pump that drugs are housed.Two pedals are set in the case during training, rat touches one of them can obtain drugs through micro-injection pump, another then can not obtain, animal pedal at random during beginning, through training after a while, rat is improved greatly to the pedal frequency of effective pedal of obtaining drugs, has obtained the animal of addiction thus.Therefore the proximate addiction process of having simulated the people of this animal model is widely used for scientific research.Of paramount importance in the whole model is the maintenance of jugular vein intubate, for preventing biting of mouse, prior art disclose make the jugular vein intubate outer body by a soft spring, and soft spring must be connected to the rat back part and could effectively prevent to bite.The above-mentioned research of this area need be produced and a kind ofly soft spring and rat is connected smoothly and the as far as possible little animal behavior experiment apparatus that influences, and seems significant.This apparatus not only is used for the self administration of addiction medicine, and is used for all rat vein administration models.
This type of at present external research silica gel nooses that adopt more, promptly the rat fore paw stretches into silica gel noose front end, and spring is linked through the back in the noose rear end.Owing to involve great expense, domestic not have the unit that adopts substantially, and domestic more employing punching or cut the method in hole promptly cuts two holes on cloth or other materials, the fore paw of rat is stretched into, rear portion connection spring.Above-mentioned two kinds of methods have common drawback, and promptly uncomfortable biting of being caused greatly influenced the state of rat, particularly domestic method, the mouth of experimental rat are often blocked by cloth and are caused damage, even badly mutilated, the not only state of influence experiment mouse, and influence has disturbed experiment normally to carry out.
Summary of the invention
The purpose of this utility model provides a kind of laboratory animal Mus and uses equipment, more particularly, provide a kind of can make experiment with rat be connected on the experimental provision can safety intravenously administrable, and free within the specific limits active laboratory animal equipment, also title " X " type Mus clothing.
This utility model is mainly made and is formed by velcro, medical rubber cream.This utility model is made up of " X " type rubber plaster 1, the two-sided velcro 2 of hook floss and hook face velcro 3.This utility model is sewn on " X " type rubber plaster two ends respectively with two-sided velcro of hook floss and hook face velcro, and " X " type rubber plaster medial surface that will contact with the animal fore paw is trimmed to arc.
Described " X " type rubber plaster is bonded by four rubber plasters, two twenty percents, 90 degree.
The two-sided velcro of described hook floss is sewed up by a hook face velcro and a matte velcro and is formed
Described hook face velcro is a 4CM*3CM hook face velcro.
This utility model can make rat be connected on the spring of self administration of medication experimental provision, and minimum to the free movable influence of rat, has that the animal of making is comfortable and easy to wear, the rate that bites is low, the state influence is little, firm in structure, anti-characteristics such as draw, cheap of pulling.
Utilize this utility model, can carry out following several animal training scheme:
The intensive training of the addiction model of 1 various addiction class medicines (morphine, cocaine, methamphetamine etc.) comprises the power of drug-seeking behavior, behavioristics's motivation etc.
The addiction model of 2 various addiction class medicines (morphine, cocaine, methamphetamine etc.) give up training, observe withdrawal symptom etc.
The training of disappearing of the addiction model of 3 various addiction class medicines (morphine, cocaine, methamphetamine etc.).
Reverting to take drugs of the addiction model of 4 various addiction class medicines (morphine, cocaine, methamphetamine etc.) comprises drug-induced revert to take drugs and clue is brought out and reverted to take drugs etc.
5 pairs can intravenously administrable cardiovascular drugs monitor of the influence of its pharmacotoxicological effect to behavioristics and rat integrality.
6 pairs can intravenously administrable its pharmacotoxicological effect of antibiosis rope drug monitoring to the influence of behavioristics and rat integrality.
7 pairs can intravenously administrable nervus centripetalis and its pharmacotoxicological effect of efferent nervous system drug monitoring to the influence of behavioristics and rat integrality.
8 pairs can intravenously administrable medicine for central nervous system monitor of the influence of its pharmacotoxicological effect to behavioristics and rat integrality.
9 pairs can intravenously administrable antipyretic-antalgic, antiinflammatory, rheumatism, immune drug monitor of the influence of its pharmacotoxicological effect to behavioristics and rat integrality.
10 pairs can intravenously administrable blood and medicine for urological system monitor of the influence of its pharmacotoxicological effect to behavioristics and rat integrality.
11 pairs can intravenously administrable breathing, digestion and its pharmacotoxicological effect of reproductive system drug monitoring to the influence of behavioristics and rat integrality.
12 pairs can intravenously administrable its pharmacotoxicological effect of hormonal system drug monitoring to the influence of behavioristics and rat integrality.
13 pairs can intravenously administrable its pharmacotoxicological effect of activity in vivo material drug monitoring to the influence of behavioristics and rat integrality.
14 pairs can intravenously administrable its pharmacotoxicological effect of chemotherapy tumor medicine drug monitoring to the influence of behavioristics and rat integrality.
15 pairs can intravenously administrable its pharmacotoxicological effect of radiotherapy drug monitoring to the influence of behavioristics and rat integrality.
Description of drawings
Fig. 1 is this utility model sketch map:
Wherein, 1 is " X " type rubber plaster, and 2 is the two-sided velcro of hook floss, and 3 is hook face velcro.
The specific embodiment
Adopt rubber plaster two twenty percents 90 degree of four length of a film 14CM to be bonded into " X " type rubber plaster, adopt a 4CM * 3CM hook face velcro and a 4CM * 3CM matte velcro to be stitched into the two-sided velcro of hook floss, two-sided velcro of above-mentioned hook floss and hook face velcro are sewn on " X " type rubber plaster two ends respectively, and " X " type rubber plaster medial surface that will contact with the animal fore paw is trimmed to arc, make this utility model laboratory animal equipment, also claim " X " type Mus clothing.
The experimental rat fore paw is stretched into " X " type rubber plaster, two-sided velcro matte of hook floss and hook face velcro are bonding at rat back, bonding reinforcement, the training of giving up, disappear, revert to take drugs of carrying out the addiction model of various addiction class medicines (morphine, cocaine, methamphetamine etc.) of hook floss two-sided velcro hook face and soft spring matte.
Use the good rate of maintenance of above-mentioned experiment equipment jugular vein intubate to be brought up to more than 95% by 67% of foreign literature report, the rate that bites less than 3%, cost but are the one thousandths of external silica gel noose.
Claims (5)
1. the laboratory animal Mus is used equipment, it is characterized in that forming by " X " type rubber plaster (1), the two-sided velcro of hook floss (2) and hook face velcro (3), described " X " type rubber plaster is bonded by four rubber plasters, two twenty percents, 90 degree, and two-sided velcro of described hook floss and hook face velcro are made respectively at " X " type rubber plaster two ends.
2. use equipment by the described laboratory animal Mus of claim 1, it is characterized in that the two-sided velcro of described hook floss made by a hook face velcro and a matte velcro stitching.
3. use equipment by the described laboratory animal Mus of claim 1, it is characterized in that described " X " type rubber plaster medial surface is curved.
4. use equipment by the described laboratory animal Mus of claim 1, it is characterized in that described hook face velcro or matte velcro are respectively 4CM * 3CM.
5. use equipment by the described laboratory animal Mus of claim 1, it is characterized in that wherein every long 14CM of rubber plaster of described " X " type rubber plaster.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNU2006200494286U CN201040044Y (en) | 2006-12-22 | 2006-12-22 | Instrument for laboratory animal mouse |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNU2006200494286U CN201040044Y (en) | 2006-12-22 | 2006-12-22 | Instrument for laboratory animal mouse |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN201040044Y true CN201040044Y (en) | 2008-03-26 |
Family
ID=39251746
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNU2006200494286U Expired - Fee Related CN201040044Y (en) | 2006-12-22 | 2006-12-22 | Instrument for laboratory animal mouse |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN201040044Y (en) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104224392A (en) * | 2013-06-14 | 2014-12-24 | 北京协和建昊医药技术开发有限责任公司 | Dog protecting and fixing band |
| CN104224393A (en) * | 2013-06-14 | 2014-12-24 | 北京协和建昊医药技术开发有限责任公司 | Guinea pig partial drug applying (exposure) fixing band |
| CN104224396A (en) * | 2013-06-14 | 2014-12-24 | 北京协和建昊医药技术开发有限责任公司 | Local drug application (toxicant exposure) fixing strap used for domestic rabbit |
-
2006
- 2006-12-22 CN CNU2006200494286U patent/CN201040044Y/en not_active Expired - Fee Related
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104224392A (en) * | 2013-06-14 | 2014-12-24 | 北京协和建昊医药技术开发有限责任公司 | Dog protecting and fixing band |
| CN104224393A (en) * | 2013-06-14 | 2014-12-24 | 北京协和建昊医药技术开发有限责任公司 | Guinea pig partial drug applying (exposure) fixing band |
| CN104224396A (en) * | 2013-06-14 | 2014-12-24 | 北京协和建昊医药技术开发有限责任公司 | Local drug application (toxicant exposure) fixing strap used for domestic rabbit |
| CN104224396B (en) * | 2013-06-14 | 2016-08-10 | 北京协和建昊医药技术开发有限责任公司 | Rabbit topical/contamination casting harness |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| C17 | Cessation of patent right | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20080326 Termination date: 20111222 |