CN200984178Y - Digital multifunctional mammary gland imaging system - Google Patents
Digital multifunctional mammary gland imaging system Download PDFInfo
- Publication number
- CN200984178Y CN200984178Y CN 200620014459 CN200620014459U CN200984178Y CN 200984178 Y CN200984178 Y CN 200984178Y CN 200620014459 CN200620014459 CN 200620014459 CN 200620014459 U CN200620014459 U CN 200620014459U CN 200984178 Y CN200984178 Y CN 200984178Y
- Authority
- CN
- China
- Prior art keywords
- light source
- module
- ultrasonic
- control module
- image
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Images
Landscapes
- Investigating Or Analysing Materials By Optical Means (AREA)
- Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
Abstract
A digital galactophore multifunctional image system, which comprises a computer central processing system, a programmable control module, a control panel, a light source control module, a light source generator, an infrared receiving imaging module and a picture collecting module; and further comprises a double wavelength generator, a type-B ultrasonic system and a picture analyzing and processing system; the double wavelength generator is a double wavelength LED light source which can emit 760 nm and 850 nm infrared light alternately; the type-B ultrasonic system comprises a convex array, a wire array probe and a type-B ultrasonic controller connected with both the convex array and the wire array probe; By using a plurality of high and new technologies such as double wavelength light organism blood oxygen content detecting, ultrasonogram and processing after monochromatic light illuminated a digitalized image, information about multiple parts and multiple organs of a human being can be achieved, so that the level, extent and type of pathological changes status can be judged, in particular the blood oxygen analyzing function reflects the metabolizable condition of the organism to a certain degree, and improves the diagnosing and analyzing level of galactophore diseases.
Description
[technical field]
This utility model relates to a kind of digital galactophore image system, particularly relates to a kind of image system that can be applicable to diagnosis of breast disease with multiple functions such as blood oxygen analysis, ultrasonic analysiss.
[background technology]
Breast carcinoma is a kind of malignant tumor of breast epithelium tissue.As other cancer, it is unusual initial from cell.Cancerous cell is different with normal cell.Its characteristics are not add control ground reproduction, and dysplasia, do not possess the function of normal mature cell, invade adjacent tissue wantonly, and the 26S Proteasome Structure and Function of normal structure is damaged.Another characteristics of cancerous cell are that adhesion strength is low, can come off from the tumor body, and intravascular or lymphatic vessel are transferred to tissue or organ at a distance.Therefore, at the late stage of breast carcinoma, not only the pathological changes of breast and thoracic wall local lesion is quite serious, and cancer also can be transferred to vitals such as liver, lung, bone and brain, brings even more serious harm to human body, even threat to life.
The M ﹠ M of breast carcinoma in the women is high, has become the principal disease that threatens women's life.The whole world has 1,200,000 people to be diagnosed as breast carcinoma every year approximately, has nearly 500,000 people to die from breast carcinoma.The breast cancer incidence of countries such as America and Europe will be higher than global level far away, shows that according to the investigation of American National ICR the year incidence rate of breast carcinoma is 85/,100,000 among the adult women.China is the low country of breast cancer incidence, and breast cancer incidence will be lower than global average level, but since the nineties in last century, the sickness rate of breast carcinoma is the trend that rises year by year, and the growth trend of China's breast carcinoma annual morbidity is 3.2% at present.In some big and medium-sized cities, breast carcinoma has become the No.1 killer in adult women's cancer mortality.
The earlier detection of breast carcinoma can be implemented excision and corresponding treatment effectively with making a definite diagnosis, thereby reduces mortality rate.Noctovisor scan breast imaging technology is a kind of easy, undamaged inspection method.The existing report of the application of infrared optics imaging detection technology in diagnosis of breast disease, reported mainly is near infrared imaging system and infrared imaging detector thereof, its principle is that infrared light has very strong penetration capacity to human body soft tissue, can be according to the hemodynamic change situation of pathological tissues, the normal group and the pathological tissues that on video image, show mammary gland, along with computer technology and development of digital image, some auxiliary diagnosis technology can make the diagnosis of mastopathy enter the level of quantitative analysis; In addition, the application of Infrared Thermogram detection method that also bibliographical information arranged, this method can scientifically reflect the metabolisable energy state and the degree of two breast tissues.For many years, these equipment and method are subjected to patient and medical worker's welcome deeply.Through numerous people's effort, diagnostic level also increases, but because disease ever-changing, still has nearly 40% mastopathy image not to be true to type, and causes difficulty to diagnosis.At this problem, people mainly were the diagnostic accordance rates from two portable high mastopathy in aspect, the one, and the performance of improvement infrared ray breast scanner, the 2nd, utilize computer that image is carried out post processing.Yet, utilize computer that image is carried out the data that post processing must be obtained based on the infrared ray galactophore scanning, therefore, how to improve the performance of infrared ray breast scanning instrument, obtain fully and accurately scan image data be undoubtedly the most key precondition.In order to obtain more galactophore scanning image information, advanced at present infrared ray galactophore scanning somascope adopts two optical filters to obtain the dual wavelength image.But single wavelength light of obtaining by two optical filters needs two video cameras to obtain, and two video cameras can not be in same position, and angle has deviation, and the data of obtaining have like this certainly existed error; And the logical luminous efficiency of optical filter is not necessarily identical, and is also uncontrollable.So, if carry out the computer image post processing according to such data, the reliability of the blood that is obtained, oxygen content result of detection is difficult to guaranteed, still be difficult to satisfy the requirement that improves the diagnosis of breast disease coincidence rate, these machines that use at present are big multi-functional all more single in addition, other are in charge of department and finish that ultrasonic spy is super to be detected also needing when ultrasonic searchlighting is handled need to carry out hospital, and formality is loaded down with trivial details and easily incur loss through delay the course of disease.
[summary of the invention]
Technical problem to be solved in the utility model is the defective that overcomes above-mentioned prior art, a kind of digital image system with multiple functions such as mammary gland blood-oxygen analysis, ultrasonic spy hypertext analysis that can be applicable to diagnosis of breast disease is provided, it can provide more high-resolution scanogram and analytical data more accurately, can provide more abundant, foundation more accurately for utilizing computer that scan-image is carried out post processing.
For achieving the above object, the technical scheme of being taked is:
The multi-functional image system of a kind of digital galactophore comprises the computer central processing system, programmable control module, control panel, light source control module, light source generator, infrared reception image-forming module and image capture module; The computer central processing system is connected by system bus with programmable control module, and control panel directly is connected with programmable control module, and light source generator connects programmable control module by light source control module; Infrared reception image-forming module is connected with the computer central processing system by image capture module, and image capture module links together with programmable control module again simultaneously; It is characterized in that: also include dual wavelength generator, B ultrasonic system and graphical analysis and processing system; Wherein the dual wavelength generator is connected with described light source control module, and the B ultrasonic system is connected with image capture module, and graphical analysis is connected with described computer central processing system with processing system;
Described dual wavelength generator is a kind of dual wavelength led light source that can alternately send 760 nanometers and 850 nanometer infrared rays;
The B ultrasonic controller that described B ultrasonic system comprises Ultrasonic-B probe and is attached thereto;
Described Ultrasonic-B probe is protruding battle array, two kinds of ultrasonic probes of linear array;
Described light source control module comprises power control circuit and light adjusting circuit, and described light adjusting circuit is a kind of control circuit that can control brightness, fluorescent lifetime, blanking time and take pictures synchronously;
Described programmable control module is PLC device able to programme or single-chip microcomputer;
Described control panel is provided with the light source selection key, takes pictures and trigger button, optical power adjustment button, cradle head control button and camera adjusting button;
Described infrared reception image-forming module is a kind of infrared pick-up head that the low-light (level) ccd sensor is housed;
Also include the mobile disk storage and case history reporting printing module and case history archive management and the information storage module that are connected with the computer central processing system.
The multi-functional image system of the described digital galactophore of technical solutions of the utility model, because what adopt is to replace luminous double-wavelength light source, under the control of light source control module, can regulate brightness, fluorescent lifetime, blanking time by actual needs, and can realize taking pictures synchronously; The B ultrasonic system then can carry out ultrasound image information to be measured, and wherein the linear array Ultrasonic-B probe is used for breast examination, and convex array probe is used for other organella inspection; In addition, add employed high resolution infrared camera and the high-quality video capture card that the low-light (level) ccd sensor is housed, make that the view data of being obtained is abundant, true, accurate and effective, provide the good premise condition for utilizing computer that scan-image is carried out post processing.
Multinomial new and high technologies such as the detection of this utility model integrated application dual wavelength light tissue blood oxygen content, ultrasonoscopy, the post processing of monochromatic light transillumination digitized image realize obtaining human body multi-section position, many organs information.In the checking process to human body noinvasive, no radiation.To the inspection of mammary gland tissue not only can make diagnostic ultrasound images also can carry out blood content collection of illustrative plates, zmount of oxygen consumption collection of illustrative plates, metabolism state level, transillumination image, multiple algorithm post processing image (window width/window position, rectangular histogram, manifest blood vessel, edge clear, etc. grey scale curve etc.), lesion region location survey or the like.Thereby obtain quantitative data and abundant qualitative information accurately, to judge pathological changes situation level, degree, pathological changes kind, optimum and pernicious, pernicious and benign trend, particularly blood oxygen analysis function has been reacted tissue metabolism's state to a certain extent, has greatly improved the diagnostic analysis level of mastopathy.
[description of drawings]
Fig. 1 and HbO2 Oxyhemoglobin and deoxyhemoglobin near infrared light zone absorption line figure;
Fig. 2 is a system architecture diagram of the present utility model;
Fig. 3 is a singlechip controller theory diagram described in the utility model;
Fig. 4 is this utility model power control circuit;
Fig. 5 is this utility model light adjusting circuit;
Fig. 6 is the mammary gland blood-oxygen functional imaging system procedure chart in this utility model;
[specific embodiment]
Be applied to clinical example below in conjunction with description of drawings and specific embodiment and understand this utility model in detail.
We know, when light when a certain uniform dielectric of extinction material is arranged, its light intensity is just weakened.And absorbed molecule share only depends on existing molecule number in the light path, and is irrelevant with the incident light intensity.If intensity is the medium of the collimated monochromatic ligth of I by a thin layer, can get transmitted light intensity by the Lambere-Bere law
I＝I
0exp[-KL]
I in the formula
0---incident intensity
I---transmitted intensity
L---by the bed thickness of medium
K---extinction coefficient or specific absorbance
Therefore, when utilizing certain light intensity transillumination mammary gland tissue, the light intensity that different tissue sites absorbs will be different, and the light intensity that transmits also will differ.Normal mammary gland tissue should be almost or all is fat.The clinical spectral wavelength that is suitable for galactophore scanning that shows is 600nm-900nm.Late nineteen seventies, Jebsis at first find, in the brain and cardiac muscle of cat, uses the near infrared light of 700nm-1000nm, two special extinction color groups occur, after be confirmed that it is hemoglobin and cytochrome.Hemoglobin is to produce the main matter that absorbs in the interior focusing of near infrared light 600nm-900nm scope, and it can be with HbO2 Oxyhemoglobin (HbO
2) and two kinds of forms existence of deoxyhemoglobin (Hb).As shown in Figure 1, HbO2 Oxyhemoglobin and deoxyhemoglobin are respectively 850nm and 760nm to the absorption peak wavelength of near infrared light, and the situation of change of its absorption curve has been reacted hemoglobin band oxygen situation.
Set up NIRS (near infrared spectrum) determination techniques according to this principle.With the specific wavelength near infrared light transillumination mammary gland tissue of certain intensity, after absorbing, it transmits, after the hemoglobin of this transillumination in mammary gland absorbs, the optical density of arrival detector (ln[T (λ, t)]) be calculated as follows:
-ln[T(λ，t)]＝ε
oxy(λ)c
oxy(t)d+ε
deoxy(λ)c
deoxy(t)d+a(λ，t)+sc(λ) (1)
ε in the formula
OxyAnd ε
DeoxyBe respectively HbO
2Specific absorbance with Hb; c
OxyAnd c
DeoxyBe respectively HbO
2Concentration with Hb; D is the optical length of light in mammary gland tissue; (λ t) is the decay that other materials cause to a; Sc (λ) is because various factors (reducing as blood supply) causes scattering and corresponding decay.
-ln[T
a(λ，t)]＝ε
oxy(λ)c’
oxy(t)d+ε
deoxy(λ)c’
deoxy(t)d+a’(λ，t)+sc(λ) (2)
" s " represents abnormal condition (reducing as blood supply).Because in near-infrared 600nm-900nm scope, the absorption of hemoglobin is a principal element, and we set that other materials cause, and to be absorbed in normal equal down with abnormal condition, and (2) formula subtracts (1) formula and gets:
-ln[T
a(λ，t)/T(λ，t)]＝ε
oxy(λ)[c’
oxy(t)-c
oxy(t)] d+ε
deoxy(λ)[c’
deoxy(t)-c
deoxy(t)] d
＝ε
oxy(λ)Δc
oxy(t)+ε
deoxy(λ)Δc
deoxy(t) (3)
Wherein
Δc
oxy(t)＝[c’
oxy(t)-c
oxy(t)]d；Δc
deoxy(t)＝[c’
deoxy(t)-c
deoxy(t)]d
Definition total hemoglobin concentration change is
Δc
total(t)＝Δc
oxy(t)+Δc
deoxy(t)
So, formulate below the variation of total hemoglobin density of a certain moment of measured zone is available:
ΔO.D
Hb.total(t)＝-ln[T
a(760，t)/T(760，t)]+-ln[T’(850，t)/T(850，t)]
＝ε
oxy(760)Δc
oxy(t)+ε
deoxy(760)Δc
deoxy(t)
+ε
oxy(850)Δc
oxy(t)+ε
deoxy(850)Δc
deoxy(t)
＝[ε
oxy(760)+ε
oxy(850)]Δc
oxy(t)
+[ε
deoxy(760)+ε
deoxy(850)]Δc
deoxy(t) (4)
According to above-mentioned requirements and principle, design the led light source that two wavelength are respectively 760nm and 850nm, the mammary gland tissue at same position carries out transillumination.
Analyze the structure of native system now: the native system primary structure comprises that the high-performance computer that the intel pentium microprocessor is housed constitutes the computer central processing system, programmable control module adopts single-chip microcomputer or PLC device able to programme, infrared reception image-forming module adopts the infrared camera that the low-light (level) ccd sensor is housed, image capture module adopts high speed image acquisition board, the dual wavelength generator adopts can replace luminous double-wavelength light source, this light source can send 760 nanometers and 850 nanometer infrared rays, light source adopts halogen tungsten lamp, also comprises the B ultrasonic system with frequency conversion linear array and the two ultrasonic probes of protruding battle array.As shown in Figure 2, the computer central processing system is connected by system bus with programmable control module, and control panel directly is connected with programmable control module, and light source generator connects programmable control module by light source control module; Infrared reception image-forming module is connected with the computer central processing system by image capture module, and image capture module links together with programmable control module again simultaneously; The dual wavelength generator is connected with described light source control module, and the B ultrasonic system is connected with image capture module, and graphical analysis is connected with described computer central processing system with processing system; The image that obtains after image that obtains after the irradiation of dual wavelength generator and the Ultrasonic-B probe irradiation enters the computer central processing system through image capture module, and the post-processing algorithm of image and oxygen content algorithm and B ultrasonic analysis etc. are all write in software, after image analysis system and processing system receive the view data that central processing unit transmits, provide instruction, fast processing.Singlechip controller theory diagram as shown in Figure 3, light source control module comprises power control circuit and light adjusting circuit, light adjusting circuit can be controlled brightness, fluorescent lifetime, blanking time by the instruction that single-chip microcomputer or PLC device able to programme send, and can also control synchronously and take pictures.
The power control circuit design as shown in Figure 4.That the semiconductor LED utensil has is low in energy consumption, characteristics such as volume is little, efficient is high, available electric excitation form the led light source into first-selection.LED diode automatic power control circuitry APC makes optical output power keep constant by the drive current that changes the LED diode.LD is the LED diode, and PD is a light sensitive diode.The two is contained in the same pipe.When luminous output strengthened, light sensitive diode sensitization intensity also strengthened, and its sensitization on-state rate is also improved, and the internal resistance of PD correspondingly reduces.Thereby make audion U
B1Reduce I
C1Increase U
C1=Ub2 increases, I
C2Reduce U
E2=U
B3Increase, Ic3 reduces, I
LDReduce.Promptly also just diminish by the electric current among the LED diode LD.Otherwise, when optical power down,, thereby make the optical output power of LD keep constant automatically because the effect of APC circuit can improve power output.Regulate the Vr potentiometer and can set the operating current of LED diode, change optical output power.Generally speaking, the operating current that is adopted is 50mA.
And being designed to as shown in Figure 5 of light adjusting circuit.This circuit adopts bidirectional triode thyristor to carry out AC voltage adjusting.Bidirectional triode thyristor is a three-terminal element, and its three end is called the T1 utmost point and the T2 utmost point respectively, and G is the control utmost point.The control utmost point comes triggering and conducting by a two-phase trigger tube (two-way excitation diode) T.No matter institute's making alive is extremely gone up in control all can make the controllable silicon conducting for positive trigger impulse or negative trigger impulse.Bidirectional triode thyristor has the advantage that volume is little, in light weight, efficient is high and easy to use.When civil power during at positive half cycle, the T2 utmost point bears positive phase voltage, give trigger impulse after, conducting immediately, electric current flows back to civil power from the controllable silicon load (transformator 2 inputs) of flowing through.When positive half-wave changes to zero, the controllable silicon automatic cut-off.When negative half period, T1 bears positive phase voltage, give trigger impulse after, conducting immediately, electric current flows back to civil power from load through controllable silicon.When negative half period changes to zero, since voltage zero-cross, the controllable silicon automatic cut-off.What obtain at the load two ends like this, is an alternating voltage.If change the moment that trigger impulse occurs, carry out phase shift within the specific limits, then can obtain a variable alternating current at the load two ends.Realized this function by R2, R3, C2, C3, the phase shift RC network formed.Regulate W and can control the moment that C3 goes up the trigger impulse arrival, thereby changed the two-phase silicon controlled angle of flow, promptly changed the output voltage in the load.Like this, through transformator 2, institute's making alive is up to 12V on the cold intense light source, can regulate arbitrarily below the 12V.The output of light source is 100W to the maximum, can regulate arbitrarily below the 100W.
The infrared pick-up head that the low-light (level) ccd sensor is housed is installed on the The Cloud Terrace, the infrared pick-up head is connected with single-chip microcomputer or PLC device able to programme through drive circuit with the shooting The Cloud Terrace, can control the action of shooting The Cloud Terrace and photographic head by single-chip microcomputer or PLC device able to programme.Light source generator, dual wavelength generator and infrared camera all are arranged on and are convenient to soft group of position of scanning of human body, and Ultrasonic-B probe also is arranged on and is convenient to soft group of position of scanning of human body, and miscellaneous part all is arranged on the rack the inside.When patient being done blood oxygen and check, control different light sources patient's mammary gland tissue is carried out noctovisor scan.Because different tissues is to the infrared ray absorbing rate difference of different frequency, after doing synchronous recording by infrared camera, after by image capture module view data being handled, be transferred to the computer central processing system and carry out pictorial display, and image analysis system and processing system receive after the view data that central processing unit transmits by dedicated program view data are done after the further post processing, carry out pictorial display again, make accurate diagnosis to make things convenient for the doctor; When carrying out ultrasound diagnosis, process also as the blood sample inspection, repeats no more once more.
The technical parameter of ccd video camera is as follows among the embodiment of the present utility model:
Picture number: 752 * 582
Definition: 600 lines
Minimal illumination: 0.01 lux/F1.2
Signal to noise ratio: 〉=48db
The technical parameter of B ultrasonic system is as follows among the embodiment of the present utility model:
Show: B ultrasonic, B/B type, B/M type, M-scan scope: 220nm, scanning angle is variable
Ultrasonic scanning line density: the maximum frame per second of 128 lines/frame: 36 frame/seconds
Display resolution: 800 * 600 investigation depths 〉=190mm
Side direction (laterally) resolving power≤2mm is (vertical definition)≤1mm axially
Blind area≤5mm geometric position precision: laterally≤49, vertically≤49
Digital scan converter: 512 * 512 * 8bit
Four kinds of image multiplying powers: 38 kinds of position labellings that have probe mark
In addition, the mobile disk that also has that is connected with the computer central processing system is stored and case history reporting printing module, electronic medical record system (EMR) is realized medical record management, file, retrieval and communication by the management to the data base, case history writings and image information is by printer output, and can carry out the mobile disk storage.
Fig. 6 is the multi-functional image system procedure chart of this utility model digital galactophore.Near infrared light breast imaging process is at first sent infrared light and part visible light by infrared light sources, penetrates target---skin of mammary gland and soft tissue.The human body different tissues is to the selective Absorption of infrared light, and the light after penetrating changes into the signal of telecommunication after highly sensitive infrared camera collection, enters MICROCOMPUTER PROCESSING and is transformed into two dimensional image and is presented on the computer monitor screen, for analyzing and diagnosing.Concrete stream of action is to as shown by arrows.The state of image depends on the anatomical structure, physiological and pathological state of breast tissue and actively penetrates infrared light intensity.Usually, fatty tissue is high printing opacity, and fibrous tissue, gland tissue and skin are low light transmissions.Blood (mainly being hemoglobin) light transmission is minimum, that is to say that hemoglobin is the strongest to the absorbability of light, and skin color is to not influence of image.
The oxygen content variable quantity is mapped to the be generated as example of picture with 8 gray level images.Monochromatic dual wavelength (760 nanometers and 850 nano wave lengths) rayed, CCD receives imaging, and analog digital conversion, 24 of image attributes, 3 R6B colouring informations, 8 (256 rank half-tone information) are realized in the back; Generate four width of cloth images of strong side of two wavelength and Ipsilateral respectively.The utilization Method of Mathematical Physics is carried out computing to the gray value of four width of cloth images, obtains two groups of new numerical value.Two groups of numerical value and corresponding original graph picture point position color separation form the pixel of same resolution, form blood changes of contents spirogram and oxygen content respectively and change spirogram (be called for short blood and contain spirogram and oxygen content figure).
Whether the measured being suffered from the diagnosis of the grade malignancy of breast tumor and tumor is mainly undertaken by palpation, graphical analysis, three steps of pathological anatomy.And graphical analysis of the present utility model is played assosting effect for the doctor makes judgement.
Galactophore scanning figure can reduce five types: 1, aberrant angiogenesis phase (increase slightly or increase).2, single-shot or multiple Lycoperdon polymorphum Vitt extinction shadow.3, the dark-grey or black light-absorbing group of peripheral type.4, reality black light-absorbing group.5, the dark-grey or black light-absorbing group of vascular type.
The foundation of computerized near infrared scan diagnosing mammary cancer is: (1) ghost is greater than actual lump, and gray scale is inhomogeneous, irregularity boundary; (2) blood vessel image is specific variations: the limitation vascular plexus increases, thick, bent, the interruption of blood vessel, and closely related with the ghost form.Meet above two and think typical breast carcinoma image, the specific variations of ghost change or blood vessel image is then highly suspected breast carcinoma.The near infrared light image analysis showed of different pathological types breast carcinoma, near infrared light image typical case ghost comes changes obvious more, and this tumor is tending towards high grade of malignancy more.Simple ghost figure or simple vessel graph mostly be the low tumor of grade malignancy or tumor early stage.
The lump major diameter 2～5cm and＞case of 5cm, the computerized near infrared scan multipotency shows typical ghost comes change figure, the accuracy of its diagnosing mammary cancer is higher, the breast carcinoma of lump major diameter＜2cm is low because of its content of hemoglobin, and lump develops lighter, does not even develop, but peripheral vessels still can have change in various degree, by means of computer image analysis and processing system, to image amplify, in-depth analysis such as enhancing, grey value, also can make correct diagnosis.
Below add up (according to national drug clinical experiment base clinical trial basic document) for the clinical testing data that utilizes this utility model to do:
◆ No.1 Hospital Affiliated to Zhongshan Univ.'s check result:
| The blood oxygen condition | Cyclomastopathy | Mammary gland fibroma | Breast carcinoma | |
| High blood | Hyperoxia | 15 | 25 | |
| Flat oxygen | 5 | 1 | 1 | |
| Hypoxia | 3 | 1 | 3 | |
| Low blood | Hyperoxia | 11 | 3 | |
| Flat oxygen | 3 | 1 | ||
| Hypoxia | 2 | 1 |
Synopsis:
| Check case | The B ultrasonic conclusion | General infrared digital galactophore inspection | Pathological examination |
| Cyclomastopathy | 37 | 38 | Done 2 examples, conformed to |
| Mammary gland fibroma | 34 | 33 | Done 5 examples, 4 examples conform to |
| Breast carcinoma | 4 | 4 | 4 |
◆ the No.2 Hospital Attached to Zhongshan Univ check result:
| The blood oxygen condition | Cyclomastopathy | Mammary gland fibroma | Breast carcinoma | |
| High blood | Hyperoxia | 8 | 4 | |
| Flat oxygen | 1 | 1 | ||
| Hypoxia | 1 | 1 | 4 | |
| Low blood | Hyperoxia | 7 | 2 | |
| Flat oxygen | 1 | 1 | ||
| Hypoxia | ||||
Synopsis:
| Check case | The B ultrasonic conclusion | General infrared digital galactophore inspection | Pathological examination |
| Cyclomastopathy | 18 | 17 | Done 3 examples, conformed to |
| Mammary gland fibroma | 8 | 9 | Done 2 examples, conformed to |
| Breast carcinoma | 5 | 5 | 4 examples conform to, the not malingering inspection of 1 example |
Oxygen content classification ratio:
| The sick kind | n | Oxygen content classification ratio (%) | |||||
| High blood hyperoxia | The flat oxygen of high blood | High blood hypoxia | Low blood hypoxia | The low flat oxygen of blood | Low blood hyperoxia | ||
| Breast carcinoma | 9 | 0 | 22 | 78 | 0 | 0 | 0 |
| Benign tumor | 40 | 72.5 | 2.5 | 5 | 2.5 | 5 | 12.5 |
| Cyclomastopathy | 57 | 40 | 10.5 | 7 | 3.5 | 7 | 32 |
Obtain following clinical trial conclusion by above data: the multi-functional image system of digital galactophore of the present utility model is easy to use, clear picture, about 65% galactophore image is the typical case, effect was pretty good after the image person of not being true to type used this machine blood oxygen analysis and process software, some information that former figure lacks and oxygen content variable quantity (metabolism state) can be provided, improved diagnostic level, No.1 Hospital Affiliated to Zhongshan Univ.'s 75 example diagnosis meet 69 examples (92%).No.2 Hospital Attached to Zhongshan Univ 31 example diagnosis meet 29 examples (93.5%).That traditional mammary gland infrared inspection has is painless, noinvasive, characteristics such as can check repeatedly, but higher misdiagnosis rate is arranged.After native system has increased image digitization technology, post-processing technology and blood oxygen analysis technology and B ultrasonic analytical technology, improved diagnostic accordance rate, particularly blood oxygen analysis function has been reacted tissue metabolism's state to a certain extent, and clinical diagnosis is had very big directive significance.
Claims (9)
1. the multi-functional image system of digital galactophore comprises the computer central processing system, programmable control module, control panel, light source control module, light source generator, infrared reception image-forming module and image capture module; The computer central processing system is connected by system bus with programmable control module, and control panel directly is connected with programmable control module, and light source generator connects programmable control module by light source control module; Infrared reception image-forming module is connected with the computer central processing system by image capture module, and image capture module links together with programmable control module again simultaneously; It is characterized in that: also include dual wavelength generator, B ultrasonic system and graphical analysis and processing system; Wherein the dual wavelength generator is connected with described light source control module, and the B ultrasonic system is connected with image capture module, and graphical analysis is connected with described computer central processing system with processing system.
2. the multi-functional image system of digital galactophore according to claim 1 is characterized in that: described dual wavelength generator is a kind of dual wavelength led light source that can alternately send 760 nanometers and 850 nanometer infrared rays.
3. the multi-functional image system of digital galactophore according to claim 1 is characterized in that: the B ultrasonic controller that described B ultrasonic system comprises Ultrasonic-B probe and is attached thereto.
4. the multi-functional image system of digital galactophore according to claim 3 is characterized in that: described Ultrasonic-B probe is protruding battle array, two kinds of ultrasonic probes of linear array.
5. the multi-functional image system of digital galactophore according to claim 1, it is characterized in that: described light source control module comprises power control circuit and light adjusting circuit, and described light adjusting circuit is a kind of control circuit that can control brightness, fluorescent lifetime, blanking time and take pictures synchronously.
6. the multi-functional image system of digital galactophore according to claim 1 is characterized in that: described programmable control module is PLC device able to programme or single-chip microcomputer.
7. the multi-functional image system of digital galactophore according to claim 1 is characterized in that: described control panel is provided with the light source selection key, takes pictures and trigger button, optical power adjustment button, cradle head control button and camera adjusting button.
8. the multi-functional image system of digital galactophore according to claim 1 is characterized in that: described infrared reception image-forming module is a kind of infrared pick-up head that the low-light (level) ccd sensor is housed.
9. the multi-functional image system of digital galactophore according to claim 1 is characterized in that: also include the mobile disk storage and case history reporting printing module and case history archive management and the information storage module that are connected with the computer central processing system.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 200620014459 CN200984178Y (en) | 2006-08-31 | 2006-08-31 | Digital multifunctional mammary gland imaging system |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 200620014459 CN200984178Y (en) | 2006-08-31 | 2006-08-31 | Digital multifunctional mammary gland imaging system |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN200984178Y true CN200984178Y (en) | 2007-12-05 |
Family
ID=38913638
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 200620014459 Expired - Lifetime CN200984178Y (en) | 2006-08-31 | 2006-08-31 | Digital multifunctional mammary gland imaging system |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN200984178Y (en) |
Cited By (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101976303A (en) * | 2010-10-21 | 2011-02-16 | 中山大学 | Breast mass and calcific benign-malignant automatic recognition and quantitative image evaluation system |
| CN102018497A (en) * | 2010-12-30 | 2011-04-20 | 广州宝胆医疗器械科技有限公司 | Superficial vascular display instrument |
| CN102164543A (en) * | 2009-03-31 | 2011-08-24 | 富士胶片株式会社 | Image processing apparatus and method and program |
| CN102551794A (en) * | 2010-12-16 | 2012-07-11 | 李百祺 | Ultrasonic diagnostic system and handheld ultrasonic diagnostic device thereof |
| CN102920429A (en) * | 2012-10-07 | 2013-02-13 | 吴士明 | Integrated device of mastopathy diagnosis and treatment |
| CN104382558A (en) * | 2014-11-21 | 2015-03-04 | 南京星顿医疗科技有限公司 | Double-mode mammary gland three-dimensional imaging device and method |
| CN104434217A (en) * | 2014-11-19 | 2015-03-25 | 成都迅德科技有限公司 | Ultrasonic probe |
| CN104939841A (en) * | 2015-05-22 | 2015-09-30 | 杨亚军 | Infrared breast blood oxygen diagnostic apparatus and method |
| WO2015154547A1 (en) * | 2014-04-11 | 2015-10-15 | 重庆莱美药业股份有限公司 | New use of nano carbon injection suspension |
| CN106264454A (en) * | 2016-07-27 | 2017-01-04 | 武汉海数字医疗科技股份有限公司 | A kind of mammary gland blood-oxygen content detection merges sense of touch imaging and the device of ultra sonic imaging |
| CN106618501A (en) * | 2016-12-29 | 2017-05-10 | 哈尔滨工业大学 | Tumor imaging system based on near-infrared spectrum blood oxygen concentration measurement and experiment detection method of system |
| CN109394181A (en) * | 2018-12-05 | 2019-03-01 | 吉林大学 | A kind of brain functional area positioning system, method and movable equipment |
| CN110013319A (en) * | 2019-02-20 | 2019-07-16 | 广州乔铁医疗科技有限公司 | Mirror system outside a kind of novel robot |
| WO2022237171A1 (en) * | 2021-05-10 | 2022-11-17 | 浙江大学台州研究院 | Dual-wavelength infrared blood oxygen measurement system based on ccd |
-
2006
- 2006-08-31 CN CN 200620014459 patent/CN200984178Y/en not_active Expired - Lifetime
Cited By (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102164543A (en) * | 2009-03-31 | 2011-08-24 | 富士胶片株式会社 | Image processing apparatus and method and program |
| CN101976303B (en) * | 2010-10-21 | 2013-09-04 | 中山大学 | Breast mass and calcific benign-malignant automatic recognition and quantitative image evaluation system |
| CN101976303A (en) * | 2010-10-21 | 2011-02-16 | 中山大学 | Breast mass and calcific benign-malignant automatic recognition and quantitative image evaluation system |
| CN102551794A (en) * | 2010-12-16 | 2012-07-11 | 李百祺 | Ultrasonic diagnostic system and handheld ultrasonic diagnostic device thereof |
| CN102018497A (en) * | 2010-12-30 | 2011-04-20 | 广州宝胆医疗器械科技有限公司 | Superficial vascular display instrument |
| CN102920429A (en) * | 2012-10-07 | 2013-02-13 | 吴士明 | Integrated device of mastopathy diagnosis and treatment |
| WO2014053080A1 (en) * | 2012-10-07 | 2014-04-10 | Wu Shiming | Integrated diagnosis/treatment device for mastopathy |
| CN102920429B (en) * | 2012-10-07 | 2014-12-03 | 吴士明 | Integrated device of mastopathy diagnosis and treatment |
| WO2015154547A1 (en) * | 2014-04-11 | 2015-10-15 | 重庆莱美药业股份有限公司 | New use of nano carbon injection suspension |
| CN104434217A (en) * | 2014-11-19 | 2015-03-25 | 成都迅德科技有限公司 | Ultrasonic probe |
| CN104382558A (en) * | 2014-11-21 | 2015-03-04 | 南京星顿医疗科技有限公司 | Double-mode mammary gland three-dimensional imaging device and method |
| CN104939841A (en) * | 2015-05-22 | 2015-09-30 | 杨亚军 | Infrared breast blood oxygen diagnostic apparatus and method |
| CN106264454A (en) * | 2016-07-27 | 2017-01-04 | 武汉海数字医疗科技股份有限公司 | A kind of mammary gland blood-oxygen content detection merges sense of touch imaging and the device of ultra sonic imaging |
| CN106618501A (en) * | 2016-12-29 | 2017-05-10 | 哈尔滨工业大学 | Tumor imaging system based on near-infrared spectrum blood oxygen concentration measurement and experiment detection method of system |
| CN106618501B (en) * | 2016-12-29 | 2021-05-04 | 哈尔滨工业大学 | Tumor imaging system based on near infrared spectrum blood oxygen concentration measurement and experimental detection method thereof |
| CN109394181A (en) * | 2018-12-05 | 2019-03-01 | 吉林大学 | A kind of brain functional area positioning system, method and movable equipment |
| CN110013319A (en) * | 2019-02-20 | 2019-07-16 | 广州乔铁医疗科技有限公司 | Mirror system outside a kind of novel robot |
| WO2022237171A1 (en) * | 2021-05-10 | 2022-11-17 | 浙江大学台州研究院 | Dual-wavelength infrared blood oxygen measurement system based on ccd |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN200984178Y (en) | Digital multifunctional mammary gland imaging system | |
| Godavarty et al. | Optical imaging for breast cancer prescreening | |
| US5007428A (en) | Apparatus for examining a body of living tissues | |
| Ntziachristos et al. | MRI-guided diffuse optical spectroscopy of malignant and benign breast lesions | |
| CN100463644C (en) | Non-invasive early cervical carcinoma detecting infrared diffused ray system and method | |
| ES2474720T3 (en) | Apparatus and method for obtaining breast images by volumetric computed tomography with cynical beam | |
| KR20150087258A (en) | Efficient modulated imaging | |
| CN100418477C (en) | Mammary gland blood oxygen function imaging method and system | |
| US10674918B2 (en) | Near-infrared (NIR) optical scanner | |
| Moesta et al. | Contrast features of breast cancer in frequency-domain laser scanning mammography | |
| Geslien et al. | Transillumination in breast cancer detection: screening failures and potential | |
| WO2018214298A1 (en) | Non-invasive blood glucose detection system and method | |
| CN109044282A (en) | The detection device and detection method of fusion tactile sensing and optical tomograph imaging | |
| CN109124569B (en) | Medical detection and imaging noninvasive diagnosis system | |
| CN201079390Y (en) | Double-waveband infrared mammary gland disease diagnostic instrument | |
| US20090069695A1 (en) | Device for imaging a turbid medium | |
| CN1802121A (en) | System and method for identifying and classifying dynamic thermodynamic processes in mammals and discriminating between and among such processes | |
| CN106308835A (en) | Handheld optical and Gamma detector integrated image system and method | |
| CN206261606U (en) | A kind of external nasopharyngeal cavity vena systemica blood oxygen saturation imaging device | |
| CN202699104U (en) | Multispectral imaging detector for breast cancer | |
| CN114624217A (en) | System for detecting skin cancer lesion degree based on multispectral fluorescence lifetime | |
| Ma et al. | Fiber-free parallel-plane continuous wave breast diffuse optical tomography system | |
| CN105212946A (en) | Portable fluorescence iraser Image detection instrument | |
| US8395120B2 (en) | Bidirectional optical scanner assisting in mammography | |
| CN205094402U (en) | Portable fluorescence laser detector |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| CX01 | Expiry of patent term |
Granted publication date: 20071205 |
|
| EXPY | Termination of patent right or utility model |