CN1986793A - Pulmonary thromboembolism related gene and its application - Google Patents
Pulmonary thromboembolism related gene and its application Download PDFInfo
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Abstract
The present invention discloses one group of pulmonary thromboembolism related genes and their application in preparing reagent for diagnosing pulmonary thromboembolism. By means of gene chip technology, the present invention provides one kind of new method for diagnosing pulmonary thromboembolism.
Description
One, technical field
The invention belongs to field of molecular biotechnology, more specifically, the present invention relates to one group of gene and application thereof relevant with human PTE.
Two, background technology
Pulmonary infarction is meant the free back obstruction of the intrasystem embolus of systemic vein pulmonary vascular bed, wherein 99% embolus is a thrombus character, be also referred to as PTE (pulmonarythromboembolism PTE), its embolus 90% derives from abdominal cavity and lower limb thrombosis.At present, people generally believe that pulmonary infarction and venous thrombosis are two different stepss of a disease.Up to the present, the west only a few countries reported the estimation sickness rate of venous thrombosis and PTE in colony's research.In western countries, the annual morbidity of total crowd's venous thrombosis and PTE surpasses 100,000 examples, and is almost the same with myocardial infarction common.The ICOPER multi-center clinical trial studies confirm that sickness rate has obvious rising trend.Although China's pulmonary infarction lacks large-scale epidemiological study, diagnose routine number to be reported in year by year and significantly raise.
The clinical manifestation of pulmonary infarction is variation, and is comparatively complicated, and pulmonary infarction patient's is 11% dead in morbidity 1 hour, and it is not rarely seen particularly occurring in postoperative, finds that in clinical same operation is not that pulmonary infarction all takes place, only for wherein a part of.Therefore, American-European countries has adopted preventive measures to different Hazard Factor with different operation wounds, comprises chemoprophylaxis and machinery prevention, nonetheless, still has the generation pulmonary infarction, and big area prevention simultaneously lacks individual specificity, also is the waste of resource.80% pulmonary infarction patient occurs in 30% specific crowd, and therefore under same outside atmosphere and wound condition, the research of its internal factor is very necessary.
In recent years, numerous scholars to have proposed pulmonary infarction and venous thrombosis be because a kind of polygene/multi-factor disease that heredity and/or environmental abnormality cause.Have a large amount of transgenations in the human body, gene pleiomorphism, gene differential expression are relevant with it.Hyperhomocysteinemiainjury, anti-phospholipid antibody syndromes, Zinc metallopeptidase Zace1 (ACE) gene insertion/deletion polymorphism etc. may take place to develop relevant with pulmonary infarction due to factor V gene Leiden sudden change, thrombogen gene G20210A sudden change, activated protein C opposing, PROTEIN C genetic flaw albumen, Protein S genetic flaw, Antithrombin III transgenation, Profibrinolysin hereditary defect, plasminogen activator inhibitor gene pleiomorphism, the gene pleiomorphism.Because the understanding of pulmonary infarction is started late, cause diagnosis, treatment, the prevention level of China's pulmonary infarction still to fall behind in China, the fatal pulmonary embolism patient that a large amount of national therefore diseases are caused injury, disabled, death, particularly operation back take place is of common occurrence.Therefore, the method that can provide a kind of early gene to diagnose, the genetic mechanism that can further investigate pulmonary infarction and venous thrombosis are provided the meaning that research detects pulmonary infarction and the examination of venous thrombosis genes involved, reduce the incidence of pulmonary infarction, mortality ratio is significant.
Biochip technology is a kind of high-new Protocols in Molecular Biology.Its ultimate principle is that a large amount of nucleic acid molecule are fixed on the upholder, hybridizes the quantity of target molecule in power by detecting hybridization signal and then the judgement sample then with the sample of mark.Gene chip has been used in explores and finds pathogenic related gene.
The present invention is by utilizing biochip technology to realize purpose of the present invention.
Three, summary of the invention
The purpose of this invention is to provide one group of genes involved relevant with PTE, another object of the present invention is the application of above-mentioned genes involved in the diagnostic kit of preparation PTE.
The present invention is by utilizing biochip technology to filter out the genes involved relevant with PTE, to realize the object of the invention.Concrete steps are:
(1) selection of research object: the random collecting clinical imageology is determined the pulmonary infarction patient and the normal health collator of diagnosis, is divided into 2 groups, the man: woman=1: 1
(2) sample is prepared: gather the research object peripheral blood, after the centrifugal treating, total RNA isolates mRNA in the extracting granulocyte from total RNA of purifying.
(3) probe preparation: this experiment adopts the mRNA reverse transcription to become cDNA, is masterplate with cDNA second chain under the effect of T7 RNA polymerase then, is substrate with the CTP that contains the CyDye mark and the Nucleotide of unmarked NTPs, synthesizes the cRNA that has the CyDye mark.The fluorescent probe of experiment difference anamorphic zone Cy5 and Cy3.
(4) preparation of gene chip: the human full genome oligonucleotide chip of U.S. Agilent company is adopted in this experiment, chip carries out conventional processing, and the processed conventionally method of chip is according to Agilent chip service manual (Agilent low RNA input fluorescent linearamplification kit protocol).
(5) chip hybridization and processing: take out fluorescent samples probe hybridization through quantitative Cy3 and Cy5 mark on gene chip, hybridization after processing such as washing chip scan immediately.
(6) data processing and analysis: image scanning, data read, analysis, standardization, Ratio analyze, cluster software cluster analysis result.
(7) find out the pulmonary infarction genes involved: find out the pulmonary infarction genes involved by analysis-by-synthesis.
Specifically set forth content of the present invention below in conjunction with embodiment
Random collecting lung embolism patients 9 examples, normal health collator's 20 examples, the man: woman=1: 1, each extracts 2ml venous blood, the EDTA anti-freezing.
The blood sample of 20 routine normal controls is respectively got 100 μ l mix, obtain RNA with the extracting of trizol method; 9 routine lung embolism patients blood samples obtain RNA with the extracting of trizol method respectively.After confirming that after testing RNA is up-to-standard, carry out the mark hybrid experiment.
The experiment marking method adopts Ambion linear amplification (Ambion
_MessageAmp
TMIIaRNA Kit) marking method combines and behind the Agilent, and wherein case group RNA adopts the cy3 fluorescent mark, and control group RNA adopts fluorescence cy5 mark.The Cy3 probe is got 80pmol, and the cy5 probe is got 40pmol and hybridized, and hybridizing method adopts 60 ℃, the hybridization of rolling in 16 hours, and develop a film in room temperature.Chip used is the full genome oligo of Agilent people chip, and the chip product catalog number (Cat.No.) is G4112A.
Chip results adopts the Agilent scanner to scan, Imagene software reading of data Scan resolution 10 μ m, PMT 70%, adopt Feature Extration to carry out the Normalize Treatment Analysis at last, obtaining ratio value (cy3/cy5) is experimental group/control group, relatively two groups difference.It is experimental group/control group.
9 routine patients' result carries out cluster analysis, according to statistical analysis principle, use genespring and cluster analysis software, to the analytical procedure that a plurality of genes with identical statistics behavior are sorted out, the gene that is classified as bunch may be similar or related on function.In the gene that 9 routine patient's variation tendencies are identical after cluster analysis, according to the nosogenesis of GO classification in conjunction with pulmonary infarction, the differential gene screening criteria is: the pulmonary infarction group is compared with control group, and every blood coagulation, the fibrinolytic relevant with thrombosis take place to raise or the gene of downward modulation variation all is selected in.
Table one, by express spectra experimental analysis to peripheral blood and normal people's peripheral blood of pulmonary infarction patient period of disease, find out the identical gene of variation tendency in 9 routine patients by cluster cluster and GO classified information, and according to this specification sheets differential gene screening criteria, therefrom filter out and 142 of pulmonary thromboembolism related genes, described gene all has corresponding GenBank number in the U.S. state-run biotechnology information center (NCBI) genetic sequence database.Specifically see the following form:
Table: pulmonary thromboembolism related gene
| SEQ ID NO： | GenBank number | SEQ ID NO： | GenBank number | SEQ ID NO： | GenBank number |
| 1 | NM_000602 | 51 | NM_000133 | 101 | NM_006016 |
| 2 | NM_016337 | 52 | NM_000161 | 102 | NM_006163 |
| 3 | NM_000821 | 53 | NM_000173 | 103 | NM_006207 |
| 4 | NM_000941 | 54 | NM_000175 | 104 | NM_006528 |
| 5 | NM_002371 | 55 | NM_000185 | 105 | NM_006682 |
| 6 | NM_000552 | 56 | NM_000212 | 106 | NM_007059 |
| 7 | NM_006152 | 57 | NM_000214 | 107 | NM_007181 |
| 8 | NM_000062 | 58 | NM_000301 | 108 | NM_007351 |
| 9 | NM_002658 | 59 | NM_000312 | 109 | NM_012137 |
| 10 | NM_000582 | 60 | NM_000313 | 110 | NM_013974 |
| 11 | NM_006404 | 61 | NM_000361 | 111 | NM_014071 |
| 12 | NM_000625 | 62 | NM_000377 | 112 | NM_014413 |
| 13 | NM_000903 | 63 | NM_000398 | 113 | NM_014432 |
| 14 | NM_002192 | 64 | NM_000448 | 114 | NM_019863 |
| 15 | X06374 | 65 | NM_000488 | 115 | NM_020244 |
| 16 | NM_002608 | 66 | NM_000504 | 116 | NM_020353 |
| 17 | NM_000930 | 67 | NM_000506 | 117 | NM_020860 |
| 18 | X61037 | 68 | NM_000508 | 118 | NM_020998 |
| 19 | NM_013314 | 69 | NM_000611 | 119 | NM_021105 |
| 20 | NM_005102 | 70 | NM_000628 | 120 | NM_021257 |
| 21 | NM_000857 | 71 | NM_000716 | 121 | NM_021870 |
| 22 | NM_002191 | 72 | NM_000849 | 122 | NM_022081 |
| 23 | NM_000419 | 73 | NM_000856 | 123 | NM_022788 |
| 24 | NM_024408 | 74 | NM_000892 | 124 | NM_024420 |
| 25 | NM_004557 | 75 | NM_000893 | 125 | NM_030984 |
| 26 | D12799 | 76 | NM_000948 | 126 | NM_031935 |
| SEQ ID NO： | GenBank number | SEQ ID NO： | GenBank number | SEQ ID NO： | GenBank number |
| 27 | NM_000953 | 77 | NM_000952 | 127 | NM_052828 |
| 28 | NM_000675 | 78 | NM_000960 | 128 | NM_139028 |
| 29 | NM_001992 | 79 | NM_001154 | 129 | NM_152753 |
| 30 | NM_005242 | 80 | NM_001172 | 130 | NM_170604 |
| 31 | NM_000572 | 81 | NM_001250 | 131 | NM_173050 |
| 32 | M57765 | 82 | NM_001737 | 132 | NM_201636 |
| 33 | NM_002563 | 83 | NM_001769 | 133 | X04665 |
| 34 | NM_000956 | 84 | NM_001776 | 134 | X55656 |
| 35 | NM_000959 | 85 | NM_001993 | 135 | NM_000054 |
| 36 | X96710 | 86 | NM_001994 | 136 | NM_001953 |
| 37 | AB030655 | 87 | NM_002203 | 137 | NM_000505 |
| 38 | AB035073 | 88 | NM_002659 | 138 | NM_000407 |
| 39 | AF080214 | 89 | NM_003746 | 139 | NM_000174 |
| 40 | AF147435 | 90 | NM_003891 | 140 | NM_000558 |
| 41 | BC000807 | 91 | NM_004101 | 141 | NM_000517 |
| 42 | BC015186 | 92 | NM_004283 | 142 | D70835 |
| 43 | BC015514 | 93 | NM_004467 | ||
| 44 | BC020719 | 94 | NM_004469 | ||
| 45 | BC032831 | 95 | NM_004488 | ||
| 46 | M27087 | 96 | NM_004579 | ||
| 47 | NM_000072 | 97 | NM_005041 | ||
| 48 | NM_000128 | 98 | NM_005141 | ||
| 49 | NM_000130 | 99 | NM_005570 | ||
| 50 | NM_000131 | 100 | NM_005618 |
For realizing another goal of the invention of the present invention, with above-mentioned relevant 142 genes with PTE, the oligonucleotide probe of synthetic correspondence, mode by the contact point sample, with probe stationary on the sheet base, preparation gene chip and related preparation detection reagent are formed detection kit, can be applicable to the early detection and the diagnosis of PTE.The present invention has bright development prospect.
The gene order table
＜110〉people from Tongji University learns hospital of attached Tongji University
＜120〉pulmonary thromboembolism related gene and application thereof
<160>142
<210>1
<211>2876
<212>DNA
＜213〉human (Homo sapiens)
<400>1
1 gaattcctgc agctcagcag ccgccgccag agcaggacga accgccaatc gcaaggcacc
61 tctgagaact tcaggatgca gatgtctcca gccctcacct gcctagtcct gggcctggcc
121 cttgtctttg gtgaagggtc tgctgtgcac catcccccat cctacgtggc ccacctggcc
181 tcagacttcg gggtgagggt gtttcagcag gtggcgcagg cctccaagga ccgcaacgtg
241 gttttctcac cctatggggt ggcctcggtg ttggccatgc tccagctgac aacaggagga
301 gaaacccagc agcagattca agcagctatg ggattcaaga ttgatgacaa gggcatggcc
361 cccgccctcc ggcatctgta caaggagctc atggggccat ggaacaagga tgagatcagc
421 accacagacg cgatcttcgt ccagcgggat ctgaagctgg tccagggctt catgccccac
481 ttcttcaggc tgttccggag cacggtcaag caagtggact tttcagaggt ggagagagcc
541 agattcatca tcaatgactg ggtgaagaca cacacaaaag gtatgatcag caacttgctt
601 gggaaaggag ccgtggacca gctgacacgg ctggtgctgg tgaatgccct ctacttcaac
661 ggccagtgga agactccctt ccccgactcc agcacccacc gccgcctctt ccacaaatca
721 gacggcagca ctgtctctgt gcccatgatg gctcagacca acaagttcaa ctatactgag
781 ttcaccacgc ccgatggcca ttactacgac atcctggaac tgccctacca cggggacacc
841 ctcagcatgt tcattgctgc cccttatgaa aaagaggtgc ctctctctgc cctcaccaac
901 attctgagtg cccagctcat cagccactgg aaaggcaaca tgaccaggct gccccgcctc
961 ctggttctgc ccaagttctc cctggagact gaagtcgacc tcaggaagcc cctagagaac
1021 ctgggaatga ccgacatgtt cagacagttt caggctgact tcacgagtct ttcagaccaa
1081 gagcctctcc acgtcgcgca ggcgctgcag aaagtgaaga tcgaggtgaa cgagagtggc
1141 acggtggcct cctcatccac agctgtcata gtctcagccc gcatggcccc cgaggagatc
1201 atcatggaca gacccttcct ctttgtggtc cggcacaacc ccacaggaac agtccttttc
1261 atgggccaag tgatggaacc ctgaccctgg ggaaagacgc cttcatctgg gacaaaactg
1321 gagatgcatc gggaaagaag aaactccgaa gaaaagaatt ttagtgttaa tgactctttc
1381 tgaaggaaga gaagacattt gccttttgtt aaaagatggt aaaccagatc tgtctccaag
1441 accttggcct ctccttggag gacctttagg tcaaactccc tagtctccac ctgagaccct
1501 gggagagaag tttgaagcac aactccctta aggtctccaa accagacggt gacgcctgcg
1561 ggaccatctg gggcacctgc ttccacccgt ctctctgccc actcgggtct gcagacctgg
1621 ttcccactga ggccctttgc aggatggaac tacggggctt acaggagctt ttgtgtgcct
1681 ggtagaaact atttctgttc cagtcacatt gccatcactc ttgtactgcc tgccaccgcg
1741 gaggaggctg gtgacaggcc aaaggccagt ggaagaaaca ccctttcatc tcagagtcca
1801 ctgtggcact ggccacccct ccccagtaca ggggtgctgc aggtggcaga gtgaatgtcc
1861 cccatcatgt ggcccaactc tcctggcctg gccatctccc tccccagaaa cagtgtgcat
1921 gggttatttt ggagtgtagg tgacttgttt actcattgaa gcagatttct gcttcctttt
1981 atttttatag gaatagagga agaaatgtca gatgcgtgcc cagctcttca ccccccaatc
2041 tcttggtggg gaggggtgta cctaaatatt tatcatatcc ttgcccttga gtgcttgtta
2101 gagagaaaga gaactactaa ggaaaataat attatttaaa ctcgctccta gtgtttcttt
2161 gtggtctgtg tcaccgtatc tcaggaagtc cagccacttg actggcacac acccctccgg
2221 acatccagcg tgacggagcc cacactgcca ccttgtggcc gcctgagaccctcgcgcccc
2281 ccgcgccccc cgcgcccctc tttttcccct tgatggaaat tgaccataca atttcatcct
2341 ccttcagggg atcaaaagga cggagtgggg ggacagagac tcagatgagg acagagtggt
2401 ttccaatgtg ttcaatagat ttaggagcag aaatgcaagg ggctgcatga cctaccagga
2461 cagaactttc cccaattaca gggtgactca cagccgcatt ggtgactcac ttcaatgtgt
2521 catttccggc tgctgtgtgt gagcagtgga cacgtgaggg gggggtgggt gagagagaca
2581 ggcagctcgg attcaactac cttagataat atttctgaaa acctaccagc cagagggtag
2641 ggcacaaaga tggatgtaat gcactttggg aggccaaggc gggaggattg cttgagccca
2701 ggagttcaag accagcctgg gcaacatacc aagacccccg tctctttaaa aatatatata
2761 ttttaaatat acttaaatat atatttctaa tatctttaaa tatatatata tattttaaag
2821 accaatttat gggagaattg cacacagatg tgaaatgaat gtaatctaat agaagc
＜110〉Attached Tongji Hospital, Tongji Univ.
＜120〉pulmonary thromboembolism related gene and application thereof
<160>142
<210>2
<211>1853
<212>DNA
＜213〉human (Homo sapiens)
<400>2
1 gagggtctgt ggtcctctga tcaacatagg ctggtgggag tacaggactc gcctcctcag
61 ggttccctgt gctgccactt ttcagccatg gccacaagtg aacagagtat ctgccaagcc
121 cgggcttccg tgatggtcta cgatgacacc agtaagaaat gggtaccaat caaacctggc
181 cagcagggat tcagccggat caacatctac cacaacactg ccagcaacac cttcagagtc
241 gttggagtca agttgcagga tcagcaggtt gtgatcaatt attcaatcgt gaaagggctg
301 aagtacaatc aggccacgcc aaccttccac cagtggcgag atgcccgcca ggtctacggc
361 ttaaactttg caagtaaaga agaggcaacc acgttctcca atgcaatgct gtttgccctg
421 aacatcatga attcccaaga aggaggcccc tccagccagc gtcaggtgca gaatggcccc
481 tctcctgatg agatggacat ccagagaaga caagtgatgg agcagcacca gcagcagcgt
541 caggaatctc tagaaagaag aacctcggcc acagggccca tcctcccacc aggacatcct
601 tcatctgcag ccagcgcccc cgtctcatgt agtgggcctc caccgccccc cccaccccca
661 gtcccacctc cacccactgg ggctacccca cctcccccac ccccactgcc agccggagga
721 gcccaggggt ccagccacga cgagagctcc atgtcaggac tggccgctgc catagctggg
781 gccaagctga gaagagtcca acggccagaa gacgcatctg gaggctccag tcccagtggg
841 acctcaaagt ccgatgccaa ccgggcaagc agcgggggtg gcggaggagg cctcatggag
901 gaaatgaaca aactgctggc caagaggaga aaagcagcct cccagtcaga caagccagcc
961 gagaagaagg aagatgaaag ccaaatggaa gatcctagta cctccccctc tccggggacc
1021 cgagcagcca gccagccacc taactcctca gaggctggcc ggaagccctg ggagcggagc
1081 aactcggtgg agaagcctgt gtcctcgatt ctgtccagaa ccccgtctgt ggcaaagagc
1141 cccgaagcta agagccccct tcagtcgcag cctcactcta ggatgaagcc tgctgggagc
1201 gtgaatgaca tggccctgga tgccttcgac ttggaccgga tgaagcagga gatcctagag
1261 gaggtggtga gagagctcca caaggtgaag gaggagatca tcgacgccat caggcaggag
1321 ctgagtggga tcagcaccac gtaaggggcc ggcctcgctg cgctgattcg tcgagcccat
1381 ccggcgacag aggacagcca gaagcccagc cagccccaga ctccagtgca ccagagcacg
1441 cacaggagcc tgggcgcgct gctgtgaaac gtcctgacct gtgatcacac atgacagtga
1501 ggaaaccaag tgcaactcct gggttttttt agattctgcc tgacacggaa caccaggtct
1561 gctcgtcttt tttgtgtttt atatttgctt atttaaggta catttctttg ggtttctaga
1621 gacgccccta agtcacctgc ttcattagac ggtttccagg ttttctccca ggtgacgctg
1681 ttagcgcctc agctggcggt gacagccggc ccagcgtggc gccaccacac accgcagagc
1741 tgtccaggca cagctccgtc cccagcgctc atggtgttga aactgtctgt catgcaccac
1801 ggtgtctgtg tccacacagt aataaacggt ttactgtccg caaaaaaaaa aaa
＜110〉Attached Tongji Hospital, Tongji Univ.
＜120〉pulmonary thromboembolism related gene and application thereof
<160>142
<210>3
<211>3236
<212>DNA
＜213〉human (Homo sapiens)
<400>3
1 gtgacccacc tgcctcctcc gcagagcaat ggcggtgtct gccgggtccg cgcggacctc
61 gcccagctca gataaagtac agaaagacaa ggctgaactg atctcagggc ccaggcagga
121 cagccgaata gggaaactct tgggttttga gtggacagat ttgtccagtt ggcggaggct
181 ggtgaccctg ctgaatcgac caacggaccc tgcaagctta gctgtctttc gttttctttt
241 tgggttcttg atggtgctag acattcccca ggagcggggg ctcagctctc tggaccggaa
301 ataccttgat gggctggatg tgtgccgctt ccccttgctg gatgccctac gcccactgcc
361 acttgactgg atgtatcttg tctacaccat catgtttctg ggggcactgg gcatgatgct
421 gggcctgtgc taccggataa gctgtgtgtt attcctgctg ccatactggt atgtgtttct
481 cctggacaag acatcatgga acaaccactc ctatctgtat gggttgttgg cctttcagct
541 aacattcatg gatgcaaacc actactggtc tgtggacggt ctgctgaatg cccataggag
601 gaatgcccac gtgccccttt ggaactatgc agtgctccgt ggccagatct tcattgtgta
661 cttcattgcg ggtgtgaaaa agctggatgc agactgggtt gaaggctatt ccatggaata
721 tttgtcccgg cactggctct tcagtccctt caaactgctg ttgtctgagg agctgactag
781 cctgctggtc gtgcactggg gtgggctgct gcttgacctc tcagctggtt tcctgctctt
841 ttttgatgtc tcaagatcca ttggcctgtt ctttgtgtcc tacttccact gcatgaattc
901 ccagcttttc agcattggta tgttctccta cgtcatgctg gccagcagcc ctctcttctg
961 ctcccctgag tggcctcgga agctggtgtc ctactgcccc cgaaggttgc aacaactgtt
1021 gcccctcaag gcagcccctc agcccagtgt ttcctgtgtg tataagagga gccggggcaa
1081 aagtggccag aagccagggc tgcgccatca gctgggagct gccttcaccc tgctctacct
1141 cctggagcag ctattcctgc cctattctca ttttctcacc cagggctata acaactggac
1201 aaatgggctg tatggctatt cctgggacat gatggtgcac tcccgctccc accagcacgt
1261 gaagatcacc taccgtgatg gccgcactgg cgaactgggc taccttaagc ctggggtatt
1321 tacacagagt cggcgatgga aggatcatgc agacatgctg aagcaatatg ccacttgcct
1381 gagccgcctg cttcccaagt ataatgtcac tgagccccag atctactttg atatttgggt
1441 ctccatcaat gaccgcttcc agcagaggat ttttgaccct cgtgtggaca tcgtgcaggc
1501 cgcttggtca ccctttcagc gcacatcctg ggtgcaacca ctcttgatgg acctgtctcc
1561 ctggagggcc aagttacagg aaatcaagag cagcctagac aaccacactg aggtggtctt
1621 cattgcagat ttccctggac tgcacttgga gaattttgtg agtgaagacc tgggcaacac
1681 tagcatccag ctgctgcagg gggaagtgac tgtggagctt gtggcagaac agaagaacca
1741 gactcttcga gagggagaaa aaatgcagtt gcctgctggt gagtaccata aggtgtatac
1801 gacatcacct agcccttctt gctacatgta cgtctatgtc aacactacag agcttgcact
1861 ggagcaagac ctggcatatc tgcaagaatt aaaggaaaag gtggagaatg gaagtgaaac
1921 agggcctcta cccccagagc tgcagcctct gttggaaggg gaagtaaaag ggggccctga
1981 gccaacacct ctggttcaga cctttcttag acgccaagaa aggctccagg agattgaacg
2041 ccggcgaaat actcctttcc atgagcgatt cttccgcttc ttgttgcgaa agctctatgt
2101 ctttcgccgc agcttcctga tgacttgtat ctcacttcga aatctgatat taggccgtcc
2161 ttccctggag cagctggccc aggaggtgac ttatgcaaac ttgagaccct ttgaggcagt
2221 tggagaactg aatccctcaa acacggattc ttcacattct aatcctcctg agtcaaatcc
2281 tgatcctgtc cactcagagt tctgaagggg gccagatgtt gggtgcagat gtagaagcag
2341 ccagtcacag acccattcta tgcaatggac atttatttga aaaaaattct caaaagtttt
2401 tttttttttt ttgggggggc ggggttctaa agctgttttt aactccgaga ttacaactta
2461 gaggaaccaa ggaaataaag caaataagat ttaacaaccc aagattaaga ggccaggaag
2521 aggttagacg caatgtgaaa ctgtcctcct aggataaggt ttaaagtggc tttttggggg
2581 ctgggtgccg tggctcacgc ctgtaatccc agcattttgg gaggctgagg tgggcagatc
2641 acttgaggcc aggagttcga gaccagcctg gccaacatgg caaaacccct tctctactaa
2701 aaatacaaaa attagccaga cgtggtggtg ggtgcctgta atccaactac ccaggaggct
2761 gaggcatgag aatcgcttgg gcccaggagg tggaggttgc agtgagccga gatcgagcca
2821 ctgcactcct gggcaacaga gcaagacttc gtctcaaaat aaataaataa agtggctctt
2881 ggggaaaagc aatttaatgt accacgatga atagctaact gttcccaagt gtttgctatg
2941 tgcaacacac cgcgtgagca gtgttacctg cattattaca ttaggctgag aggtaaaata
3001 atttgcccga agacatacag ctagtgacga atggactgat ggtttgaact taacgtctat
3061 ttgacttaag gtcctgcacc ctgccacttg taattttcag aatcactgat aatctgaaat
3121 aatgcagctt aaaacatgtt ttcttaatta aaagtataaa aaaaaaaaaa aaaaaaaaaa
3181 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaa
＜110〉Attached Tongji Hospital, Tongji Univ.
＜120〉pulmonary thromboembolism related gene and application thereof
<160>142
<210>4
<211>2446
<212>DNA
＜213〉human (Homo sapiens)
<400>4
1 ggctgccagc gtttcatgat caacatggga gactcccacg tggacaccag ctccaccgtg
61 tccgaggcgg tggccgaaga agtatctctt ttcagcatga cggacatgat tctgttttcg
121 ctcatcgtgg gtctcctaac ctactggttc ctcttcagaa agaaaaaaga agaagtcccc
181 gagttcacca aaattcagac attgacctcc tctgtcagag agagcagctt tgtggaaaag
241 atgaagaaaa cggggaggaa catcatcgtg ttctagggct cccagacggg gactgcagag
301 gagtttgcca accgcctgtc caaggacgcc caccgctacg ggatgcgagg catgtcagcg
361 gaccctgagg agtatgacct ggccgacctg agcagcctgc cagagatcga caacgccctg
421 gtggttttct gcatggccac ctacggtgag ggagacccca ccgacaatgc ccaggacttc
481 tacgactggc tgcaggagac agacgtggat ctctctgggg tcaagttcgc ggtgtttggt
541 cttgggaaca agacctacga gcacttcaat gccatgggca agtacgtgga caagcggctg
601 gagcagctcg gcgcccagcg catctttgag ctggggttgg gcgacgacga tgggaacttg
661 gaggaggact tcatcacctg gcgagagcag ttctggctgg ccgtgtgtga acactttggg
721 gtggaagcca ctggcgagga gtccagcatt cgccagtacg agcttgtggt ccacaccgac
781 atagatgcgg ccaaggtgta catgggggag atgggccggc tgaagagcta cgagaaccag
841 aagcccccct ttgatgccaa gaatccgttc ctggctgcag tcaccaccaa ccggaagctg
901 aaccagggaa ccgagcgcca cctcatgcac ctggaattgg acatctcgga ctccaaaatc
961 aggtatgaat ctggggacca cgtggctgtg tacccagcca acgactctgc tctcgtcaac
1021 cagctgggca aaatcctggg tgccgacctg gacgtcgtca tgtccctgaa caacctggat
1081 gaggagtcca acaagaagca cccattcccg tgccctacgt cctaccgcac ggccctcacc
1141 tactacctgg acatcaccaa cccgccgcgt accaacgtgc tgtacgagct ggcgcagtac
1201 gcctcggagc cctcggagca ggagctgctg cgcaagatgg cctcctcctc cggcgagggc
1261 aaggagctgt acctgagctg ggtggtggag gcccggaggc acatcctggc catcctgcag
1321 gactgcccgt ccctgcggcc ccccatcgac cacctgtgtg agctgctgcc gcgcctgcag
1381 gcccgctact actccatcgc ctcatcctcc aaggtccacc ccaactctgt gcacatctgt
1441 gcggtggttg tggagtacga gaccaaggcc ggccgcatca acaagggcgt ggccaccaac
1501 tggctgcggg ccaaggagcc tgtcggggag aacggcggcc gtgcgctggt gcccatgttc
1561 gtgcgcaagt cccagttccg cctgcccttc aaggccacca cgcctgtcat catggtgggc
1621 cccggcaccg gggtggcacc cttcataggc ttcatccagg agcgggcctg gctgcgacag
1681 cagggcaagg aggtggggga gacgctgctg tactacggct gccgccgctc ggatgaggac
1741 tacctgtacc gggaggagct ggcgcagttc cacagggacg gtgcgctcac ccagctcaac
1801 gtggccttct cccgggagca gtcccacaag gtctacgtcc agcacctgct aaagcaagac
1861 cgagagcagc tgtggaagtt gatcgaaggc ggtgcccaca tctacgtctg tggggatgca
1921 cggaacatgg ccagggatgt gcagaacacc ttctacgaca tcgtggctga gctcggggcc
1981 atggagcacg cgcaggcggt ggactacatc aagaaactga tgaccaaggg ccgctactcc
2041 ctggacgtgt ggagctaggg gcctgcctgc cccacccacc ccacagactc cggcctgtaa
2101 tcagctctcc tggctccctc ccgtagtctc ctgggtgtgt ttggcttggc cttggcatgg
2161 gcgcaggccc agtgacaaag actcctctgg gcctggggtg catcctcctc agcccccagg
2221 ccaggtgagg tccaccggcc cctggcagca cagcccaggg cctgcatggg ggcaccgggc
2281 tccatgcctc tggaggcctc tggccctcgg tggctgcaca gaagggctct ttctctctgc
2341 tgagctgggc ccagcccctc cacatgattt ccagtgagtg taaataattt taaataacct
2401 ctggcccttg gaataaagtt ctgttttctg taaaaaaaaa aaaaaa
＜110〉Attached Tongji Hospital, Tongji Univ.
＜120〉pulmonary thromboembolism related gene and application thereof
<160>142
<210>5
<211>1056
<212>DNA
＜213〉human (Homo sapiens)
<400>5
1 gtctgcgcgg agtctgagcg gcgctcgtcc cgtcccaagg ccgacgccag cacgccgtca
61 tggcccccgc agcggcgacg gggggcagca ccctgcccag tggcttctcg gtcttcacca
121 ccttgcccga cttgctcttc atctttgagt ttatcttcgg gggcctggtg tggatcctgg
181 tggcctcctc cctggtgccc tggcccctgg tccagggctg ggtgatgttc gtgtctgtgt
241 tctgcttcgt ggccaccacc accttgatca tcctgtacat aattggagcc cacggtggag
301 agacttcctg ggtcaccttg gacgcagcct accactgcac cgctgccctc ttttacctca
361 gcgcctcagt cctggaggcc ctggccacca tcacgatgca agacggcttc acctacaggc
421 actaccatga aaacattgct gccgtggtgt tctcctacat agccactctg ctctacgtgg
481 tccatgcggt gttctcttta atcagatgga agtcttcata aagccgcagt agaacttgag
541 ctgaaaaccc agatggtgtt aactggccgc cccactttcc ggcataactt tttagaaaac
601 agaaatgccc ttgatggtgg aaaaaagaaa acaaccaccc ccccactgcc caaaaaaaaa
661 agccctgccc tgttgctcgt gggtgctgtg tttactctcc cgtgtgcctt cgcgtccggg
721 ttgggagctt gctgtgtcta acctccaact gctgtgctgt ctgctagggt cacctcctgt
781 ttgtgaaagg ggaccttctt gttcgggggt gggaagtggc gaccgtgacc tgagaaggaa
841 agaaagatcc tctgctgacc cctggagcag ctctcgagaa ctacctgttg gtattgtcca
901 caagctctcc cgagcgcccc atcttgtgcc atgttttaag tcttcatgga tgttctgcat
961 gtcatgggga ctaaaactca cccaacagat ctttccagag gtccatggtg gaagacgata
1021 accctgtgaa atactttata aaatgtctta atgttc
＜110〉Attached Tongji Hospital, Tongji Univ.
＜120〉pulmonary thromboembolism related gene and application thereof
<160>142
<210>6
<211>8923
<212>DNA
＜213〉human (Homo sapiens)
<400>6
1 agctcacagc tattgtggtg ggaaagggag ggtggttggt ggatgtcaca gcttgggctt
61 tatctccccc agcagtgggg actccacagc ccctgggcta cataacagca agacagtccg
121 gagctgtagc agacctgatt gagcctttgc agcagctgag agcatggcct agggtgggcg
181 gcaccattgt ccagcagctg agtttcccag ggaccttgga gatagccgca gccctcattt
241 gcaggggaag gcaccattgt ccagcagctg agtttcccag ggaccttgga gatagccgca
301 gccctcattt atgattcctg ccagatttgc cggggtgctg cttgctctgg ccctcatttt
361 gccagggacc ctttgtgcag aaggaactcg cggcaggtca tccaccggccc gatgcagcct
421 tttcggaagt gacttcgtca acacctttga tgggagcatg tacagctttg cgggatactg
481 cagttacctc ctggcagggg gctgccagaa acgctccttc tcgattattg gggacttcca
541 gaatggcaag agagtgagcc tctccgtgta tcttggggaa ttttttgaca tccatttgtt
601 tgtcaatggt accgtgacac agggggacca aagagtctcc atgccctatg cctccaaagg
661 gctgtatcta gaaactgagg ctgggtacta caagctgtcc ggtgaggcct atggctttgt
721 ggccaggatc gatggcagcg gcaactttca agtcctgctg tcagacagat acttcaacaa
781 gacctgcggg ctgtgtggca actttaacat ctttgctgaa gatgacttta tgacccaaga
841 agggaccttg acctcggacc cttatgactt tgccaactca tgggctctga gcagtggaga
901 acagtggtgt gaacgggcat ctcctcccag cagctcatgc aacatctcct ctggggaaat
961 gcagaagggc ctgtgggagc agtgccagct tctgaagagc acctcggtgt ttgcccgctg
1021 ccaccctctg gtggaccccg agccttttgt ggccctgtgt gagaagactt tgtgtgagtg
1081 tgctgggggg ctggagtgcg cctgccctgc cctcctggag tacgcccgga cctgtgccca
1141 ggagggaatg gtgctgtacg gctggaccga ccacagcgcg tgcagcccag tgtgccctgc
1201 tggtatggag tataggcagt gtgtgtcccc ttgcgccagg acctgccaga gcctgcacat
1261 caatgaaatg tgtcaggagc gatgcgtgga tggctgcagc tgccctgagg gacagctcct
1321 ggatgaaggc ctctgcgtgg agagcaccga gtgtccctgc gtgcattccg gaaagcgcta
1381 ccctcccggc acctccctct ctcgagactg caacacctgc atttgccgaa acagccagtg
1441 gatctgcagc aatgaagaat gtccagggga gtgccttgtc actggtcaat cccacttcaa
1501 gagctttgac aacagatact tcaccttcag tgggatctgc cagtacctgc tggcccggga
1561 ttgccaggac cactccttct ccattgtcat tgagactgtc cagtgtgctg atgaccgcga
1621 cgctgtgtgc acccgctccg tcaccgtccg gctgcctggc ctgcacaaca gccttgtgaa
1681 actgaagcat ggggcaggag ttgccatgga tggccaggac atccagctcc ccctcctgaa
1741 aggtgacctc cgcatccagc atacagtgac ggcctccgtg cgcctcagct acggggagga
1801 cctgcagatg gactgggatg gccgcgggag gctgctggtg aagctgtccc ccgtctacgc
1861 cgggaagacc tgcggcctgt gtgggaatta caatggcaac cagggcgacg acttccttac
1921 cccctctggg ctggcagagc cccgggtgga ggacttcggg aacgcctgga agctgcacgg
1981 ggactgccag gacctgcaga agcagcacag cgatccctgc gccctcaacc cgcgcatgac
2041 caggttctcc gaggaggcgt gcgcggtcct gacgtccccc acattcgagg cctgccatcg
2101 tgccgtcagc ccgctgccct acctgcggaa ctgccgctac gacgtgtgct cctgctcgga
2161 cggccgcgag tgcctgtgcg gcgccctggc cagctatgcc gcggcctgcg cggggagagg
2221 cgtgcgcgtc gcgtggcgcg agccaggccg ctgtgagctg aactgcccga aaggccaggt
2281 gtacctgcag tgcgggaccc cctgcaacct gacctgccgc tctctctctt acccggatga
2341 ggaatgcaat gaggcctgcc tggagggctg cttctgcccc ccagggctct acatggatga
2401 gaggggggac tgcgtgccca aggcccagtg cccctgttac tatgacggtg agatcttcca
2461 gccagaagac atcttctcag accatcacac catgtgctac tgtgaggatg gcttcatgca
2521 ctgtaccatg agtggagtcc ccggaagctt gctgcctgac gctgtcctca gcagtcccct
2581 gtctcatcgc agcaaaagga gcctatcctg tcggcccccc atggtcaagc tggtgtgtcc
2641 cgctgacaac ctgcgggctg aagggctcga gtgtaccaaa acgtgccaga actatgacct
2701 ggagtgcatg agcatgggct gtgtctctgg ctgcctctgc cccccgggca tggtccggca
2761 tgagaacaga tgtgtggccc tggaaaggtg tccctgcttc catcagggca aggagtatgc
2821 ccctggagaa acagtgaaga ttggctgcaa cacttgtgtc tgtcgggacc ggaagtggaa
2881 ctgcacagac catgtgtgtg atgccacgtg ctccacgatc ggcatggccc actacctcac
2941 cttcgacggg ctcaaatacc tgttccccgg ggagtgccag tacgttctgg tgcaggatta
3001 ctgcggcagt aaccctggga cctttcggat cctagtgggg aataagggat gcagccaccc
3061 ctcagtgaaa tgcaagaaac gggtcaccat cctggtggag ggaggagaga ttgagctgtt
3121 tgacggggag gtgaatgtga agaggcccat gaaggatgag actcactttg aggtggtgga
3181 gtctggccgg tacatcattc tgctgctggg caaagccctc tccgtggtct gggaccgcca
3241 cctgagcatc tccgtggtcc tgaagcagac ataccaggag aaagtgtgtg gcctgtgtgg
3301 gaattttgat ggcatccaga acaatgacct caccagcagc aacctccaag tggaggaaga
3361 ccctgtggac tttgggaact cctggaaagt gagctcgcag tgtgctgaca ccagaaaagt
3421 gcctctggac tcatcccctg ccacctgcca taacaacatc atgaagcaga cgatggtgga
3481 ttcctcctgt agaatcctta ccagtgacgt cttccaggac tgcaacaagc tggtggaccc
3541 cgagccatat ctggatgtct gcatttacga cacctgctcc tgtgagtcca ttggggactg
3601 cgcctgcttc tgcgacacca ttgctgccta tgcccacgtg tgtgcccagc atggcaaggt
3661 ggtgacctgg aggacggcca cattgtgccc ccagagctgc gaggagagga atctccggga
3721 gaacgggtat gagtgtgagt ggcgctataa cagctgtgca cctgcctgtc aagtcacgtg
3781 tcagcaccct gagccactgg cctgccctgt gcagtgtgtg gagggctgcc atgcccactg
3841 ccctccaggg aaaatcctgg atgagctttt gcagacctgc gttgaccctg aagactgtcc
3901 agtgtgtgag gtggctggcc ggcgttttgc ctcaggaaag aaagtcacct tgaatcccag
3961 tgaccctgag cactgccaga tttgccactg tgatgttgtc aacctcacct gtgaagcctg
4021 ccaggagccg ggaggcctgg tggtgcctcc cacagatgcc ccggtgagcc ccaccactct
4081 gtatgtggag gacatctcgg aaccgccgtt gcacgatttc tactgcagca ggctactgga
4141 cctggtcttc ctgctggatg gctcctccag gctgtccgag gctgagtttg aagtgctgaa
4201 ggcctttgtg gtggacatga tggagcggct gcgcatctcc cagaagtggg tccgcgtggc
4261 cgtggtggag taccacgacg gctcccacgc ctacatcggg ctcaaggacc ggaagcgacc
4321 gtcagagctg cggcgcattg ccagccaggt gaagtatgcg ggcagccagg tggcctccac
4381 cagcgaggtc ttgaaataca cactgttcca aatcttcagc aagatcgacc gccctgaagc
4441 ctcccgcatc gccctgctcc tgatggccag ccaggagccc caacggatgt cccggaactt
4501 tgtccgctac gtccagggcc tgaagaagaa gaaggtcatt gtgatcccgg tgggcattgg
4561 gccccatgcc aacctcaagc agatccgcct catcgagaag caggcccctg agaacaaggc
4621 cttcgtgctg agcagtgtgg atgagctgga gcagcaaagg gacgagatcg ttagctacct
4681 ctgtgacctt gcccctgaag cccctcctcc tactctgccc ccccacatgg cacaagtcac
4741 tgtgggcccg gggctcttgg gggtttcgac cctggggccc aagaggaact ccatggttct
4801 ggatgtggcg ttcgtcctgg aaggatcgga caaaattggt gaagccgact tcaacaggag
4861 caaggagttc atggaggagg tgattcagcg gatggatgtg ggccaggaca gcatccacgt
4921 cacggtgctg cagtactcct acatggtgac cgtggagtac cccttcagcg aggcacagtc
4981 caaaggggac atcctgcagc gggtgcgaga gatccgctac cagggcggca acaggaccaa
5041 cactgggctg gccctgcggt acctctctga ccacagcttc ttggtcagcc agggtgaccg
5101 ggagcaggcg cccaacctgg tctacatggt caccggaaat cctgcctctg atgagatcaa
5161 gaggctgcct ggagacatcc aggtggtgcc cattggagtg ggccctaatg ccaacgtgca
5221 ggagctggag aggattggct ggcccaatgc ccctatcctc atccaggact ttgagacgct
5281 cccccgagag gctcctgacc tggtgctgca gaggtgctgc tccggagagg ggctgcagat
5341 ccccaccctc tcccctgcac ctgactgcag ccagcccctg gacgtgatcc ttctcctgga
5401 tggctcctcc agtttcccag cttcttattt tgatgaaatg aagagtttcg ccaaggcttt
5461 catttcaaaa gccaatatag ggcctcgtct cactcaggtg tcagtgctgc agtatggaag
5521 catcaccacc attgacgtgc catggaacgt ggtcccggag aaagcccatt tgctgagcct
5581 tgtggacgtc atgcagcggg agggaggccc cagccaaatc ggggatgcct tgggctttgc
5641 tgtgcgatac ttgacttcag aaatgcatgg tgccaggccg ggagcctcaa aggcggtggt
5701 catcctggtc acggacgtct ctgtggattc agtggatgca gcagctgatg ccgccaggtc
5761 caacagagtg acagtgttcc ctattggaat tggagatcgc tacgatgcag cccagctacg
5821 gatcttggca ggcccagcag gcgactccaa cgtggtgaag ctccagcgaa tcgaagacct
5881 ccctaccatg gtcaccttgg gcaattcctt cctccacaaa ctgtgctctg gatttgttag
5941 gatttgcatg gatgaggatg ggaatgagaa gaggcccggg gacgtctgga ccttgccaga
6001 ccagtgccac accgtgactt gccagccaga tggccagacc ttgctgaaga gtcatcgggt
6061 caactgtgac cgggggctga ggccttcgtg ccctaacagc cagtcccctg ttaaagtgga
6121 agagacctgt ggctgccgct ggacctgccc ctgcgtgtgc acaggcagct ccactcggca
6181 catcgtgacc tttgatgggc agaatttcaa gctgactggc agctgttctt atgtcctatt
6241 tcaaaacaag gagcaggacc tggaggtgat tctccataat ggtgcctgca gccctggagc
6301 aaggcagggc tgcatgaaat ccatcgaggt gaagcacagt gccctctccg tcgagctgca
6361 cagtgacatg gaggtgacgg tgaatgggag actggtctct gttccttacg tgggtgggaa
6421 catggaagtc aacgtttatg gtgccatcat gcatgaggtc agattcaatc accttggtca
6481 catcttcaca ttcactccac aaaacaatga gttccaactg cagctcagcc ccaagacttt
6541 tgcttcaaag acgtatggtc tgtgtgggat ctgtgatgag aacggagcca atgacttcat
6601 gctgagggat ggcacagtca ccacagactg gaaaacactt gttcaggaat ggactgtgca
6661 gcggccaggg cagacgtgcc agcccatcct ggaggagcag tgtcttgtcc ccgacagctc
6721 ccactgccag gtcctcctct taccactgtt tgctgaatgc cacaaggtcc tggctccagc
6781 cacattctat gccatctgcc agcaggacag ttgccaccag gagcaagtgt gtgaggtgat
6841 cgcctcttat gcccacctct gtcggaccaa cggggtctgc gttgactgga ggacacctga
6901 tttctgtgct atgtcatgcc caccatctct ggtctacaac cactgtgagc atggctgtcc
6961 ccggcactgt gatggcaacg tgagctcctg tggggaccat ccctccgaag gctgtttctg
7021 ccctccagat aaagtcatgt tggaaggcag ctgtgtccct gaagaggcct gcactcagtg
7081 cattggtgag gatggagtcc agcaccagtt cctggaagcc tgggtcccgg accaccagcc
7141 ctgtcagatc tgcacatgcc tcagcgggcg gaaggtcaac tgcacaacgc agccctgccc
7201 cacggccaaa gctcccacgt gtggcctgtg tgaagtagcc cgcctccgcc agaatgcaga
7261 ccagtgctgc cccgagtatg agtgtgtgtg tgacccagtg agctgtgacc tgcccccagt
7321 gcctcactgt gaacgtggcc tccagcccac actgaccaac cctggcgagt gcagacccaa
7381 cttcacctgc gcctgcagga aggaggagtg caaaagagtg tccccaccct cctgcccccc
7441 gcaccgtttg cccacccttc ggaagaccca gtgctgtgat gagtatgagt gtgcctgcaa
7501 ctgtgtcaac tccacagtga gctgtcccct tgggtacttg gcctcaaccg ccaccaatga
7561 ctgtggctgt accacaacca cctgccttcc cgacaaggtg tgtgtccacc gaagcaccat
7621 ctaccctgtg ggccagttct gggaggaggg ctgcgatgtg tgcacctgca ccgacatgga
7681 ggatgccgtg atgggcctcc gcgtggccca gtgctcccag aagccctgtg aggacagctg
7741 tcggtcgggc ttcacttacg ttctgcatga aggcgagtgc tgtggaaggt gcctgccatc
7801 tgcctgtgag gtggtgactg gctcaccgcg gggggactcc cagtcttcct ggaagagtgt
7861 cggctcccag tgggcctccc cggagaaccc ctgcctcatc aatgagtgtg tccgagtgaa
7921 ggaggaggtc tttatacaac aaaggaacgt ctcctgcccc cagctggagg tccctgtctg
7981 cccctcgggc tttcagctga gctgtaagac ctcagcgtgc tgcccaagct gtcgctgtga
8041 gcgcatggag gcctgcatgc tcaatggcac tgtcattggg cccgggaaga ctgtgatgat
8101 cgatgtgtgc acgacctgcc gctgcatggt gcaggtgggg gtcatctctg gattcaagct
8161 ggagtgcagg aagaccacct gcaacccctg ccccctgggt tacaaggaag aaaataacac
8221 aggtgaatgt tgtgggagat gtttgcctac ggcttgcacc attcagctaa gaggaggaca
8281 gatcatgaca ctgaagcgtg atgagacgct ccaggatggc tgtgatactc acttctgcaa
8341 ggtcaatgag agaggagagt acttctggga gaagagggtc acaggctgcc caccctttga
8401 tgaacacaag tgtctggctg agggaggtaa aattatgaaa attccaggca cctgctgtga
8461 cacatgtgag gagcctgagt gcaacgacat cactgccagg ctgcagtatg tcaaggtggg
8521 aagctgtaag tctgaagtag aggtggatat ccactactgc cagggcaaat gtgccagcaa
8581 agccatgtac tccattgaca tcaacgatgt gcaggaccag tgctcctgct gctctccgac
8641 acggacggag cccatgcagg tggccctgca ctgcaccaat ggctctgttg tgtaccatga
8701 ggttctcaat gccatggagt gcaaatgctc ccccaggaag tgcagcaagt gaggctgctg
8761 cagctgcatg ggtgcctgct gctgcctgcc ttggcctgat ggccaggcca gagtgctgcc
8821 agtcctctgc atgttctgct cttgtgccct tctgagccca caataaaggc tgagctctta
8881 tcttgctgca tgttctgctc ttgtgccctt ctgagcccac aat
＜110〉Attached Tongji Hospital, Tongji Univ.
＜120〉pulmonary thromboembolism related gene and application thereof
<160>142
<210>7
<211>2826
<212>DNA
＜213〉human (Homo sapiens)
<400>7
1 gctccaagaa accagccaac ggctggagga tgtggaggag caggtagggt ggctcatggc
61 tacattagat tcaggggaca tctcctcaga tgccctgcaa accatgaaat aaaaatggag
121 gaggaacaac aacaacaaac aaaaaaaaaa agcaaagagg aactgcaagt tcagtcccta
181 gcgactaaca gtgagcagag gaagtaaagg gggagttgta agagaggcgg tatcaacagc
241 ctgctgatga aagaggcgac tctgcagaaa gaggcaactt gacatatcag gactttaacc
301 gctgtagaaa tagctcaggc ataccaagcc catgcaaaca cagaattgca gaagttcagg
361 agaggcttat cacttccctg agaagaaaaa cacattttca gttttgcctg catcataaga
421 gtgagcactc cattgctttc tttcctggcc acactgctac aatccagcac taactatcca
481 tgtccagggt aaggatcgag atcgagaagc ccacactgcc agtgaaaaag ctacgtcttt
541 actgcataaa ttagaggaag caatttcgga acaacggaac cttcaaacta taaatactga
601 attatcgaac acttgccagg cacttcagca gaagacaagg aaactgaaga agctttttag
661 atgaggaatt tcctcactat gattccctgt cctgcgcaga tgcaattcaa caacctcttc
721 aagaaaaatt gaagcagtgt tgccacaaac tatatggtgg tcaagaagca agaatacatc
781 agacacccct gaccttgaaa catacgtgct ggtacacacc tctgctggat gccttatctc
841 tggatagttt tacagcagtt ccaaccctgg aatcaacacc tttctcaggt gtagccaacc
901 aaatccacac tctgtgtgaa aggcccacat atggagaagt aaaggatggt gctttggatg
961 taaaaagaca acacaagtgc ccaggcccca caagtggccc cagcccagga acgaatctct
1021 caggctgcat caggatgaat gatgacccaa gtatggaaga gaatggtgtt gaacgcgtgt
1081 gtcctgagag cctgctgcag tccagggaat attcctcact accattaccc agacacactt
1141 catcgacaga cggtactata acttcaagtg atcctggatt agaaattctg aatatggctt
1201 cttgtgacct tgacagaaac tcgctctgta agaaagagga ggatacaaga tcagcttctc
1261 ccacgataga ggcccaaggc acaagtccag ctcatgataa tattgcattc caagactcta
1321 cgagtaagga taaaaccata ttaaatctgg aagccaaaga ggaaccagaa acaatagaag
1381 aacataaaaa agaacatgct tcaggagact ctgtggtttc ccctcttcct gtaaccactg
1441 tgaaatcggt taaccttaga caaagtgaga acacttctgc taatgagaag gaggtggagg
1501 cagaatttct cagattatct ttgggattta agtgtgactg gtttaccttg gagaagagag
1561 tgaagcttga agagaggtcc cgtgacttgg cagaagaaaa tttgaagaaa gaaatcacta
1621 actgtttaaa actattagag tctttaacac ctctgtgtga agatgacaac caggcacagg
1681 aaatcattaa gaagctggag aagagtataa agtttcttag ccagtgtgcag cacgagtgg
1741 ccagtagggc tgagatgttg ggagccatca atcaggaaag ccgggttagt aaagcagttg
1801 aagtgatgat tcagcacgta gaaaacttga agaggatgta tgccaaagag cacgctgaat
1861 tagaagaact gaaacaggtt cttctgcaga atgaaaggtc tttcaatcct cttgaagatg
1921 atgatgactg ccaaattaaa aaacgttcag cttctctaaa ctccaagcca tcttctctac
1981 gaagagtgac tattgcctct ttacccagaa atattggaaa tgcaggaatg gtggctggga
2041 tggaaaataa tgatcgattc agtagaaggt caagcagttg gcgtattttg gggtcaaagc
2101 agagtgaaca ccgtccctca ttacctcgat ttattagcac ctattcctgg gcagatgctg
2161 aagaagaaaa atgtgaacta aaaactaaag atgactcaga gccatctgga gaagaaacag
2221 tagaaaggac aaggaagcca agtctttctg aaaagaaaaa taatccatca aagtgggatg
2281 tctcttcagt ttatgacaca atagcttcct gggcaacaaa tctcaagtcc tccatcagaa
2341 aggctaataa ggccctctgg ctctctattg cattcattgt actgtttgca gctttgatga
2401 gcttcctcac aggccaatta ttccagaagt ctgtggatgc cgctcccaca cagcaagagg
2461 actcatggac gtctctagaa catatcttgt ggccatttac cagactccga cacaatgggc
2521 caccaccagt gtgacagcag gacatcctaa tatatggatc ttgattttta agtttcagta
2581 tctgaacttc gtaaattagt aacttttagc tgggaaagta tagcatgaaa ccagaggttc
2641 tcagaatgac tgtaagatag cttacatttc ctctttttgc ctttatctcc ccaactaaaa
2701 tacaatgggg aagaagtctg cctatgatct ttgaatgagc tttttaagga agaaatatta
2761 tatattgttt gttaaagttt attgaaataa agaatcattt aaatcttcaa aaaaaaaaaa
2821 aaaaaa
＜110〉Attached Tongji Hospital, Tongji Univ.
＜120〉pulmonary thromboembolism related gene and application thereof
<160>142
<210>8
<211>1984
<212>DNA
＜213〉human (Homo sapiens)
<400>8
1 ctgatttaca ggaactcaca ccagcgatca atcttcctta atttgtaact gggcagtgtc
61 ccgggccagc caatagctaa gactgccccc cccgcacccc accctccctg accctggggg
121 actctctact cagtctgcac tggagctgcc tggtgaccag aagtttggag tccgctgacg
181 tcgccgccca gatggcctcc aggctgaccc tgctgaccct cctgctgctg ctgctggctg
241 gggatagagc ctcctcaaat ccaaatgcta ccagctccag ctcccaggat ccagagagtt
301 tgcaagacag aggcgaaggg aaggtcgcaa caacagttat ctccaagatg ctattcgttg
361 aacccatcct ggaggtttcc agcttgccga caaccaactc aacaaccaat tcagccacca
421 aaataacagc taataccact gatgaaccca ccacacaacc caccacagag cccaccaccc
481 aacccaccat ccaacccacc caaccaacta cccagctccc aacagattct cctacccagc
541 ccactactgg gtccttctgc ccaggacctg ttactctctg ctctgacttg gagagtcatt
601 caacagaggc cgtgttgggg gatgctttgg tagatttctc cctgaagctc taccacgcct
661 tctcagcaat gaagaaggtg gagaccaaca tggccttttc cccattcagc atcgccagcc
721 tccttaccca ggtcctgctc ggggctgggg agaacaccaa aacaaacctg gagagcatcc
781 tctcttaccc caaggacttc acctgtgtcc accaggccct gaagggcttc acgaccaaag
841 gtgtcacctc agtctctcag atcttccaca gcccagacct ggccataagg gacacctttg
901 tgaatgcctc tcggaccctg tacagcagca gccccagagt cctaagcaac aacagtgacg
961 ccaacttgga gctcatcaac acctgggtgg ccaagaacac caacaacaag atcagccggc
1021 tgctagacag tctgccctcc gatacccgcc ttgtcctcct caatgctatc tacctgagtg
1081 ccaagtggaa gacaacattt gatcccaaga aaaccagaat ggaacccttt cacttcaaaa
1141 actcagttat aaaagtgccc atgatgaata gcaagaagta ccctgtggcc catttcattg
1201 accaaacttt gaaagccaag gtggggcagc tgcagctctc ccacaatctg agtttggtga
1261 tcctggtacc ccagaacctg aaacatcgtc ttgaagacat ggaacaggct ctcagccctt
1321 ctgttttcaa ggccatcatg gagaaactgg agatgtccaa gttccagccc actctcctaa
1381 cactaccccg catcaaagtg acgaccagcc aggatatgct ctcaatcatg gagaaattgg
1441 aattcttcga tttttcttat gaccttaacc tgtgtgggct gacagaggac ccagatcttc
1501 aggtttctgc gatgcagcac cagacagtgc tggaactgac agagactggg gtggaggcgg
1561 ctgcagcctc cgccatctct gtggcccgca ccctgctggt ctttgaagtg cagcagccct
1621 tcctcttcgt gctctgggac cagcagcaca agttccctgt cttcatgggg cgagtatatg
1681 accccagggc ctgagacctg caggatcagg ttagggcgag cgctacctct ccagcctcag
1741 ctctcagttg cagccctgct gctgcctgcc tggacttggc ccctgccacc tcctgcctca
1801 ggtgtccgct atccaccaaa agggctccct gagggtctgg gcaagggacc tgcttctatt
1861 agcccttctc catggccctg ccatgctctc caaaccactt tttgcagctt tctctagttc
1921 aagttcacca gactctataa ataaaacctg acagaccatg actttcaaaa aaaaaaaaaa
1981 aaaa
＜110〉Attached Tongji Hospital, Tongji Univ.
＜120〉pulmonary thromboembolism related gene and application thereof
<160>142
<210>9
<211>2360
<212>DNA
＜213〉human (Homo sapiens)
<400>9
1 acagtgcgga gaccgcagcc ccggagcccg ggccagggtc cacctgtccc cgcagcgccg
61 gctcgcgccc tcctgccgca gccaccgagc cgccgtctag cgccccgacc tcgccaccat
121 gagagccctg ctggcgcgcc tgcttctctg cgtcctggtc gtgagcgact ccaaaggcag
181 caatgaactt catcaagttc catcgaactg tgactgtcta aatggaggaa catgtgtgtc
241 caacaagtac ttctccaaca ttcactggtg caactgccca aagaaattcg gagggcagca
301 ctgtgaaata gataagtcaa aaacctgcta tgaggggaat ggtcactttt accgaggaaa
361 ggccagcact gacaccatgg gccggccctg cctgccctgg aactctgcca ctgtccttca
421 gcaaacgtac catgcccaca gatctgatgc tcttcagctg ggcctgggga aacataatta
481 ctgcaggaac ccagacaacc ggaggcgacc ctggtgctat gtgcaggtgg gcctaaagcc
541 gcttgtccaa gagtgcatgg tgcatgactg cgcagatgga aaaaagccct cctctcctcc
601 agaagaatta aaatttcagt gtggccaaaa gactctgagg ccccgcttta agattattgg
661 gggagaattc accagcatcg agaaccagcc ctggtttgcg gccatctaca ggaggcaccg
721 ggggggctct gtcacctacg tgtgtggagg cagcctcatc agcccttgct gggtgatcag
781 cgccacacac tgcttcattg attacccaaa gaaggaggac tacatcgtct acctgggtcg
841 ctcaaggctt aactccaaca cgcaagggga gatgaagttt gaggtggaaa acctcatcct
901 acacaaggac tacagcgctg acacgcttgc tcaccacaac gacattgcct tgctgaagat
961 ccgttccaag gagggcaggt gtgcgcagcc atcccggact atacagacca tctgcctgcc
1021 ctcgatgtat aacgatcccc agtttggcac aagctgtgag atcactggct ttggaaaaga
1081 gaattctacc gactatctct atccggagca gctgaaaatg actgttgtga agctgatttc
1141 ccaccgggag tgtcagcagc cccactacta cggctctgaa gtcaccacca aaatgctgtg
1201 tgctgctgac ccacagtgga aaacagattc ctgccaggga gactcagggg gacccctcgt
1261 ctgttccctc caaggccgca tgactttgac tggaattgtg agctggggcc gtggatgtgc
1321 cctgaaggac aagccaggcg tctacacgag agtctcacac ttcttaccct ggatccgcag
1381 tcacaccaag gaagagaatg gcctggccct ctgagggtcc ccagggagga aacgggcacc
1441 acccgctttc ttgctggttg tcatttttgc agtagagtca tctccatcag ctgtaagaag
1501 agactgggaa gataggctct gcacagatgg atttgcctgt gccacccacc agggcgaacg
1561 acaatagctt taccctcagg cataggcctg ggtgctggct gcccagaccc ctctggccag
1621 gatggagggg tggtcctgac tcaacatgtt actgaccagc aacttgtctt tttctggact
1681 gaagcctgca ggagttaaaa agggcagggc atctcctgtg catgggtgaa gggagagcca
1741 gctcccccga cggtgggcat ttgtgaggcc catggttgag aaatgaataa tttcccaatt
1801 aggaagtgta acagctgagg tctcttgagg gagcttagcc aatgtgggag cagcggtttg
1861 gggagcagag acactaacga cttcagggca gggctctgat attccatgaa tgtatcagga
1921 aatatatatg tgtgtgtatg tttgcacact tgtgtgtggg ctgtgagtgt aagtgtgagt
1981 aagagctggt gtctgattgt taagtctaaa tatttcctta aactgtgtgg actgtgatgc
2041 cacacagagt ggtctttctg gagaggttat aggtcactcc tggggcctct tgggtccccc
2101 acgtgacagt gcctgggaat gtattattct gcagcatgac ctgtgaccag cactgtctca
2161 gtttcacttt cacatagatg tccctttctt ggccagttat cccttccttt tagcctagtt
2221 catccaatcc tcactgggtg gggtgaggac cactcctgta cactgaatat ttatatttca
2281 ctatttttat ttatattttt gtaattttaa ataaaagtga tcaataaaat gtgatttttc
2341 tgatgaaaaa aaaaaaaaaa
＜110〉Attached Tongji Hospital, Tongji Univ.
＜120〉pulmonary thromboembolism related gene and application thereof
<160>142
<210>10
<211>1616
<212>DNA
＜213〉human (Homo sapiens)
<400>10
1 ctccctgtgt tggtggagga tgtctgcagc agcatttaaa ttctgggagg gcttggttgt
61 cagcagcagc aggaggaggc agagcacagc atcgtcggga ccagactcgt ctcaggccag
121 ttgcagcctt ctcagccaaa cgccgaccaa ggaaaactca ctaccatgag aattgcagtg
181 atttgctttt gcctcctagg catcacctgt gccataccag ttaaacaggc tgattctgga
241 agttctgagg aaaagcagct ttacaacaaa tacccagatg ctgtggccac atggctaaac
301 cctgacccat ctcagaagca gaatctccta gccccacaga cccttccaag taagtccaac
361 gaaagccatg accacatgga tgatatggat gatgaagatg atgatgacca tgtggacagc
421 caggactcca ttgactcgaa cgactctgat gatgtagatg acactgatga ttctcaccag
481 tctgatgagt ctcaccattc tgatgaatct gatgaactgg tcactgattt tcccacggac
541 ctgccagcaa ccgaagtttt cactccagtt gtccccacag tagacacata tgatggccga
601 ggtgatagtg tggtttatgg actgaggtca aaatctaaga agtttcgcag acctgacatc
661 cagtaccctg atgctacaga cgaggacatc acctcacaca tggaaagcga ggagttgaat
721 ggtgcataca aggccatccc cgttgcccag gacctgaacg cgccttctga ttgggacagc
781 cgtgggaagg acagttatga aacgagtcag ctggatgacc agagtgctga aacccacagc
841 cacaagcagt ccagattata taagcggaaa gccaatgatg agagcaatga gcattccgat
901 gtgattgata gtcaggaact ttccaaagtc agccgtgaat tccacagcca tgaatttcac
961 agccatgaag atatgctggt tgtagacccc aaaagtaagg aagaagataa agacctgaaa
1021 tttcgtattt ctcatgaatt agatagtgca tcttctgagg tcaattaaaa ggagaaaaaa
1081 tacaatttct cactttgcat ttagtcaaaa gaaaaaatgc tttatagcaa aatgaaagag
1141 aacatgaaat gcttctttct cagtttattg gttgaatgtg tatctatttg agtctggaaa
1201 taactaatgt gtttgataat tagtttagtt tgtggcttca tggaaactcc ctgtaaacta
1261 aaagcttcag ggttatgtct atgttcattc tatagaagaa atgcaaacta tcactgtatt
1321 ttaatatttg ttattctctc atgaatagaa atttatgtag aagcaaacaa aatactttta
1381 cccacttaaa aagagaatat aacattttat gtcactataa tcttctgttt tttaagttag
1441 tgtatatttt gttgtgatta tctttttgtg gtgtgaataa atcttttatc ttgaatgtaa
1501 taagaatttg gtggtgtcaa ttgcttattt gttttcccac ggttgtccag caattaataa
1561 aacataacct tttttactgc ctaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaa
＜110〉Attached Tongji Hospital, Tongji Univ.
＜120〉pulmonary thromboembolism related gene and application thereof
<160>142
<210>11
<211>1483
<212>DNA
＜213〉human (Homo sapiens)
<400>11
1 gacacagtag aaataacact ttataagcct cttcctcctc ccatctcctg gcctccttcc
61 atcctcctct gcccagactc cgcccctccc agacggtcct cacttctctt ttccctagac
121 tgcagccagc ggagcccgca gccggcccga gccaggaacc caggtccgga gcctcaactt
181 caggatgttg acaacattgc tgccgatact gctgctgtct ggctgggcct tttgtagcca
241 agacgcctca gatggcctcc aaagacttca tatgctccag atctcctact tccgcgaccc
301 ctatcacgtg tggtaccagg gcaacgcgtc gctgggggga cacctaacgc acgtgctgga
361 aggcccagac accaacacca cgatcattca gctgcagccc ttgcaggagc ccgagagctg
421 ggcgcgcacg cagagtggcc tgcagtccta cctgctccag ttccacggcc tcgtgcgcct
481 ggtgcaccag gagcggacct tggcctttcc tctgaccatc cgctgcttcc tgggctgtga
541 gctgcctccc gagggctcta gagcccatgt cttcttcgaa gtggctgtga atgggagctc
601 ctttgtgagt ttccggccgg agagagcctt gtggcaggca gacacccagg tcacctccgg
661 agtggtcacc ttcaccctgc agcagctcaa tgcctacaac cgcactcggt atgaactgcg
721 ggaattcctg gaggacacct gtgtgcagta tgtgcagaaa catatttccg cggaaaacac
781 gaaagggagc caaacaagcc gctcctacac ttcgctggtc ctgggcgtcc tggtgggcag
841 tttcatcatt gctggtgtgg ctgtaggcat cttcctgtgc acaggtggac ggcgatgtta
901 attactctcc agccccctca gaaggggctg gattgatgga ggctggcaag ggaaagtttc
961 agctcactgt gaagccagac tccccaactg aaacaccaga aggtttggag tgacagctcc
1021 tttcttctcc cacatctgcc cactgaagat ttgagggagg ggagatggag aggagaggtg
1081 gacaaagtac ttggtttgct aagaacctaa gaacgtgtat gctttgctga attagtctga
1141 taagtgaatg tttatctatc tttgtggaaa acagataatg gagttggggc aggaagccta
1201 tggcccatcc tccaaagaca gacagaatca cctgaggcgt tcaaaagata taaccaaata
1261 aacaagtcat ccacaatcaa aatacaacat tcaatacttc caggtgtgtc agacttggga
1321 tgggacgctg atataatagg gtagaaagaa gtaacacgaa gaagtggtgg aaatgtaaaa
1381 tccaagtcat atggcagtga tcaattatta atcaattaat aatattaata aatttcttat
1441 atttaaggca aaaaaaaaat aaaaaaaaaa aaaaaaaaaa aaa
＜110〉Attached Tongji Hospital, Tongji Univ.
＜120〉pulmonary thromboembolism related gene and application thereof
<160>142
<210>12
<211>4221
<212>DNA
＜213〉human (Homo sapiens)
<400>12
1 ataactttgt agcgagtcga aaactgaggc tccggccgca gagaactcag cctcattcct
61 gctttaaaat ctctcggcca cctttgatga ggggactggg cagttctaga cagtcccgaa
121 gttctcaagg cacaggtctc ttcctggttt gactgtcctt accccgggga ggcagtgcag
181 ccagctgcaa gccccacagt gaagaacatc tgagctcaaa tccagataag tgacataagt
241 gacctgcttt gtaaagccat agagatggcc tgtccttgga aatttctgtt caagaccaaa
301 ttccaccagt atgcaatgaa tggggaaaaa gacatcaaca acaatgtgga gaaagccccc
361 tgtgccacct ccagtccagt gacacaggat gaccttcagt atcacaacct cagcaagcag
421 cagaatgagt ccccgcagcc cctcgtggag acgggaaaga agtctccaga atctctggtc
481 aagctggatg caaccccatt gtcctcccca cggcatgtga ggatcaaaaa ctggggcagc
541 gggatgactt tccaagacac acttcaccat aaggccaaag ggattttaac ttgcaggtcc
601 aaatcttgcc tggggtccat tatgactccc aaaagtttga ccagaggacc cagggacaag
661 cctacccctc cagatgagct tctacctcaa gctatcgaat ttgtcaacca atattacggc
721 tccttcaaag aggcaaaaat agaggaacat ctggccaggg tggaagcggt aacaaaggag
781 atagaaacaa caggaaccta ccaactgacg ggagatgagc tcatcttcgc caccaagcag
841 gcctggcgca atgccccacg ctgcattggg aggatccagt ggtccaacct gcaggtcttc
901 gatgcccgca gctgttccac tgcccgggaa atgtttgaac acatctgcag acacgtgcgt
961 tactccacca acaatggcaa catcaggtcg gccatcaccg tgttccccca gcggagtgat
1021 ggcaagcacg acttccgggt gtggaatgct cagctcatcc gctatgctgg ctaccagatg
1081 ccagatggca gcatcagagg ggaccctgcc aacgtggaat tcactcagct gtgcatcgac
1141 ctgggctgga agcccaagta cggccgcttc gatgtggtcc ccctggtcct gcaggccaat
1201 ggccgtgacc ctgagctctt cgaaatccca cctgaccttg tgcttgaggt ggccatggaa
1261 catcccaaat acgagtggtt tcgggaactg gagctaaagt ggtacgccct gcctgcagtg
1321 gccaacatgc tgcttgaggt gggcggcctg gagttcccag ggtgcccctt caatggctgg
1381 tacatgggca cagagatcgg agtccgggac ttctgtgacg tccagcgcta caacatcctg
1441 gaggaagtgg gcaggagaat gggcctggaa acgcacaagc tggcctcgct ctggaaagac
1501 caggctgtcg ttgagatcaa cattgctgtg ctccatagtt tccagaagca gaatgtgacc
1561 atcatggacc accactcggc tgcagaatcc ttcatgaagt acatgcagaa tgaataccgg
1621 tcccgtgggg gctgcccggc agactggatt tggctggtcc ctcccatgtc tgggagcatc
1681 acccccgtgt ttcaccagga gatgctgaac tacgtcctgt cccctttcta ctactatcag
1741 gtagaggcct ggaaaaccca tgtctggcag gacgagaagc ggagacccaa gagaagagag
1801 attccattga aagtcttggt caaagctgtg ctctttgcct gtatgctgat gcgcaagaca
1861 atggcgtccc gagtcagagt caccatcctc tttgcgacag agacaggaaa atcagaggcg
1921 ctggcctggg acctgggggc cttattcagc tgtgccttca accccaaggt tgtctgcatg
1981 gataagtaca ggctgagctg cctggaggag gaacggctgc tgttggtggt gaccagtacg
2041 tttggcaatg gagactgccc tggcaatgga gagaaactga agaaatcgct cttcatgctg
2101 aaagagctca acaacaaatt caggtacgct gtgtttggcc tcggctccag catgtaccct
2161 cggttctgcg cctttgctca tgacattgat cagaagctgt cccacctggg ggcctctcag
2221 ctcaccccga tgggagaagg ggatgagctc agtgggcagg aggacgcctt ccgcagctgg
2281 gccgtgcaaa ccttcaaggc agcctgtgag acgtttgatg tccgaggcaa acagcacatt
2341 cagatcccca agctctacac ctccaatgtg acctgggacc cgcaccacta caggctcgtg
2401 caggactcac agcctttgga cctcagcaaa gccctcagca gcatgcatgc caagaacgtg
2461 ttcaccatga ggctcaaatc tcggcagaat ctacaaagtc cgacatccag ccgtgccacc
2521 atcctggtgg aactctcctg tgaggatggc caaggcctga actacctgcc gggggagcac
2581 cttggggttt gcccaggcaa ccagccggcc ctggtccaag gtatcctgga gcgagtggtg
2641 gatggcccca caccccacca gacagtgcgc ctggaggccc tggatgagag tggcagctac
2701 tgggtcagtg acaagaggct gcccccctgc tcactcagcc aggccctcac ctacttcctg
2761 gacatcacca cacccccaac ccagctgctg ctccaaaagc tggcccaggt ggccacagaa
2821 gagcctgaga gacagaggct ggaggccctg tgccagccct cagagtacag caagtggaag
2881 ttcaccaaca gccccacatt cctggaggtg ctagaggagt tcccgtccct gcgggtgtct
2941 gctggcttcc tgctttccca gctccccatt ctgaagccca ggttatactc catcagctcc
3001 tcccgggatc acacgcccac agagatccac ctgactgtgg ccgtggtcac ctaccacacc
3061 cgagatggcc agggtcccct gcaccacggc gtctgcagca catggctcaa cagcctgaag
3121 ccccaagacc cagtgccctg ctttgtgcgg aatgccagcg gcttccacct ccccgaggat
3181 ccctcccatc cttgcatcct catcgggcct ggcacaggca tcgcgccctt ccgcagtttc
3241 tggcagcaac ggctccatga ctcccagcac aagggagtgc ggggaggccg catgaccttg
3301 gtgtttgggt gccgccgccc agatgaggac cacatctacc aggaggagat gctggagatg
3361 gcccagaagg gggtgctgca tgcggtgcac acagcctatt cccgcctgcc tggcaagccc
3421 aaggtctatg ttcaggacat cctgcggcag cagctggcca gcgaggtgct ccgtgtgctc
3481 cacaaggagc caggccacct ctatgtttgc ggggatgtgc gcatggcccg ggacgtggcc
3541 cacaccctga agcagctggt ggctgccaag ctgaaattga atgaggagca ggtcgaggac
3601 tatttctttc agctcaagag ccagaagcgc tatcacgaag atatctttgg tgctgtattt
3661 ccttacgagg cgaagaagga cagggtggcg gtgcagccca gcagcctgga gatgtcagcg
3721 ctctgagggc ctacaggagg ggttaaagct gccggcacag aacttaagga tggagccagc
3781 tctgcattat ctgaggtcac agggcctggg gagatggagg aaagtgatat cccccagcct
3841 caagtcttat ttcctcaacg ttgctcccca tcaagccctt tacttgacct cctaacaagt
3901 agcaccctgg attgatcgga gcctcctctc tcaaactggg gcctccctgg tcccttggag
3961 acaaaatctt aaatgccagg cctggcaagt gggtgaaaga tggaacttgc tgctgagtgc
4021 accacttcaa gtgaccacca ggaggtgcta tcgcaccact gtgtatttaa ctgccttgtg
4081 tacagttatt tatgcctctg tatttaaaaa actaacaccc agtctgttcc ccatggccac
4141 ttgggtcttc cctgtatgat tccttgatgg agatatttac atgaattgca ttttacttta
4201 atcacaaaaa aaaaaaaaaa a
＜110〉Attached Tongji Hospital, Tongji Univ.
＜120〉pulmonary thromboembolism related gene and application thereof
<160>142
<210>13
<211>2601
<212>DNA
＜213〉human (Homo sapiens)
<400>13
1 ccgcccttgt aggctgtcca cctcaaacgg gccggacagg atatataaga gagaatgcac
61 cgtgcactac acacgcgact cccacaaggt tgcagccgga gccgcccagc tcaccgagag
121 cctagttccg gccagggtcg ccccggcaac cacgagccca gccaatcagc gccccggact
181 gcaccagagc catggtcggc agaagagcac tgatcgtact ggctcactca gagaggacgt
241 ccttcaacta tgccatgaag gaggctgctg cagcggcttt gaagaagaaa ggatgggagg
301 tggtggagtc ggacctctat gccatgaact tcaatcccat catttccaga aaggacatca
361 caggtaaact gaaggaccct gcgaactttc agtatcctgc cgagtctgtt ctggcttata
421 aagaaggcca tctgagccca gatattgtgg ctgaacaaaa gaagctggaa gccgcagacc
481 ttgtgatatt ccagttcccc ctgcagtggt ttggagtccc tgccattctg aaaggctggt
541 ttgagcgagt gttcatagga gagtttgctt acacttacgc tgccatgtat gacaaaggac
601 ccttccggag taagaaggca gtgctttcca tcaccactgg tggcagtggc tccatgtact
661 ctctgcaagg gatccacggg gacatgaatg tcattctctg gccaattcag agtggcattc
721 tgcatttctg tggcttccaa gtcttagaac ctcaactgac atatagcatt gggcacactc
781 cagcagacgc ccgaattcaa atcctggaag gatggaagaa acgcctggag aatatttggg
841 atgagacacc actgtatttt gctccaagca gcctctttga cctaaacttc caggcaggat
901 tcttaatgaa aaaagaggta caggatgagg agaaaaacaa gaaatttggc ctttctgtgg
961 gccatcactt gggcaagtcc atcccaactg acaaccagat caaagctaga aaatgagatt
1021 ccttagcctg gatttccttc taacatgtta tcaaatctgg gtatctttcc aggcttccct
1081 gacttgcttt agtttttaag atttgtgttt ttctttttcc acaaggaata aatgagaggg
1141 aatcgactgt attcgtgcat ttttggatca tttttaactg attcttatga ttactatcat
1201 ggcatataac caaaatccga ctgggctcaa gaggccactt agggaaagat gtagaaagat
1261 gctagaaaaa tgttctttaa aggcatctac acaatttaat tcctcttttt agggctaaag
1321 ttttagggta cagtttggct aggtatcatt caactctcca atgttctatt aatcacctct
1381 ctgtagttta tggcagaagg gaattgctca gagaaggaaa agactgaatc tacctgccct
1441 aagggactta acttgtttgg tagttagcca tctaatgctt gtttatgata tttcttgctt
1501 tcaattacaa agcagttact aatatgccta gcacaagtac cactcttggt cagcttttgt
1561 tgtttatata cagtacacag ataccttgaa aggaagagct aataaatctc ttctttgctg
1621 cagtcatcta cttttttttt aattaaaaaa aatttttttt tgaagcagtc ttgctctgtt
1681 acccaggctg gagtgcagtg gtgtgatctc ggctcactgc aacctctgcc tcccaggttc
1741 cagcaattct cctgcctcag cctccctagt agctgggatg acaggcgcct gccatcatgc
1801 ctgactaatt tttgtatttt tagtagagac ggcgtttcac catgttggcc aggctggtct
1861 caaactcctg acctcaggtg atccgcctac ctcagcctcc caaagtgctg ggattacagg
1921 cgtgatccac cacacctggc ccttgcaatc ttctacttta aggtttgcag agataaacca
1981 ataaatccac accgtacatc tgcaatatga attcaagaaa ggaaatagta ccttcaatac
2041 ttaaaaatag tcttccacaa aaaatacttt atttctgatc tatacaaatt ttcagaaggt
2101 tattttcttt atcattgcta aactgatgac ttactatggg atggggtcca gtcccatgac
2161 cttggggtac aattgtaaac ctagagtttt atcaactttg gtgaacagtt ttggcataat
2221 agtcaatttc tacttctgga agtcatctca ttccactgtt ggtattatat aattcaagga
2281 gaatatgata aaacactgcc ctcttgtggt gcattgaaag aagagatgag aaatgatgaa
2341 aaggttgcct gaaaaatggg agacagcctc ttacttgcca agaaaatgaa gggattggac
2401 cgagctggaa aacctccttt accagatgct gactggcact ggtggttttt gctctcgaca
2461 gtatccacaa tagctgacgg ctgggtgttt cagtttgaaa atattttgtt gccttcatct
2521 tcactgcaat tttgtgtaaa tttctcaaag atctgaatta aataaataaa attcatttct
2581 acagacccac aaaaaaaaaa a
＜110〉Attached Tongji Hospital, Tongji Univ.
＜120〉pulmonary thromboembolism related gene and application thereof
<160>142
<210>14
<211>2175
<212>DNA
＜213〉human (Homo sapiens)
<400>14
1 agtacagtat aaaacttcac agtgccaata ccatgaagag gagctcagac agctcttacc
61 acatgataca agagccggct ggtggaagag tggggaccag aaagagaatt tgctgaagag
121 gagaaggaaa aaaaaaacac caaaaaaaaa aataaaaaaa tccacacaca caaaaaaacc
181 tgcgcgtgag gggggaggaa aagcagggcc ttttaaaaag gcaatcacaa caacttttgc
241 tgccaggatg cccttgcttt ggctgagagg atttctgttg gcaagttgct ggattatagt
301 gaggagttcc cccaccccag gatccgaggg gcacagcgcg gcccccgact gtccgtcctg
361 tgcgctggcc gccctcccaa aggatgtacc caactctcag ccagagatgg tggaggccgt
421 caagaagcac attttaaaca tgctgcactt gaagaagaga cccgatgtca cccagccggt
481 acccaaggcg gcgcttctga acgcgatcag aaagcttcat gtgggcaaag tcggggagaa
541 cgggtatgtg gagatagagg atgacattgg aaggagggca gaaatgaatg aacttatgga
601 gcagacctcg gagatcatca cgtttgccga gtcaggaaca gccaggaaga cgctgcactt
661 cgagatttcc aaggaaggca gtgacctgtc agtggtggag cgtgcagaag tctggctctt
721 cctaaaagtc cccaaggcca acaggactag gaccaaagtt accatccgcc tcttccagca
781 gcagaagcac ccgcagggca gcttggacac aggggaagag gccgaggaag tgggcttaaa
841 gggggagagg agtgaactgt tgctctctga aaaagtagta gacgctcgga agagcacctg
901 gcatgtcttc cctgtctcca gcagcatcca gcggttgctg gaccagggca agagctccct
961 ggacgttcgg attgcctgtg agcagtgcca ggagagtggc gccagcttgg ttctcctggg
1021 caagaagaag aagaaagaag aggaggggga agggaaaaag aagggcggag gtgaaggtgg
1081 ggcaggagca gatgaggaaa aggagcagtc gcacagacct ttcctcatgc tgcaggcccg
1141 gcagtctgaa gaccaccctc atcgccggcg tcggcggggc ttggagtgtg atggcaaggt
1201 caacatctgc tgtaagaaac agttctttgt cagtttcaag gacatcggct ggaatgactg
1261 gatcattgct ccctctggct atcatgccaa ctactgcgag ggtgagtgcc cgagccatat
1321 agcaggcacg tccgggtcct cactgtcctt ccactcaaca gtcatcaacc actaccgcat
1381 gcggggccat agcccctttg ccaacctcaa atcgtgctgt gtgcccacca agctgagacc
1441 catgtccatg ttgtactatg atgatggtca aaacatcatc aaaaaggaca ttcagaacat
1501 gatcgtggag gagtgtgggt gctcatagag ttgcccagcc cagggggaaa gggagcaaga
1561 gttgtccagg gaagacagtg gcaaaatgaa gaaattttta aggtttctga gttaaccaga
1621 aaaatagaaa ttaaaaacaa aacaaaaaaa aaaacaaaaa aaaacaaaag taaattaaaa
1681 acaaaacctg atgaaacaga tgaaggaaga tgtggaaaaa atccttagcc agggctcaga
1741 gatgaagcag tgaaagagac aggaattggg agggaaaggg agaatggtgt accctttatt
1801 tcttctgaaa tcacactgat gacatcagtt gtttaaacgg ggtattgtcc tttcccccct
1861 tgaggttccc ttgtgagcct tgaatcaacc aatctagtct gcagtagtgt ggactagaac
1921 aacccaaata gcatctagaa agccatgagt ttgaaagggc ccatcacagg cactttccta
1981 cccaattacc caggtcataa ggtatgtctg tgtgacactt atctctgtgt atatcagcat
2041 acacacacac acacacacac acacacacac acacaggcat ttccacacat tacatatata
2101 cacatactgg taaaagaaca atcgtgtgca ggtggtcaca cttccttttt ctgtaccact
2161 tttgcaacaa aacaa
＜110〉Attached Tongji Hospital, Tongji Univ.
＜120〉pulmonary thromboembolism related gene and application thereof
<160>142
<210>15
<211>2305
<212>DNA
＜213〉human (Homo sapiens)
<400>15
1 ttcttggggc tgatgtccgc aaatatgcag aattaccggc cgggtcgctc ctgaagccag
61 cgcggggagc gagcgcggcg gcggccagca ccgggaacgc accgaggaag aagcccagcc
121 cccgccctcc gccccttccg tccccacccc ctacccggcg gcccaggagg ctccccggct
181 gcggcgcgca ctccctgttt ctcctcctcc tggctggcgc tgcctgcctc tccgcactca
241 ctgctcgccg ggcgccgtcc gccagctccg tgctccccgc gccaccctcc tccgggccgc
301 gctccctaag ggatggtact gaatttcgcc gccacaggag accggctgga gcgcccgccc
361 cgcgcctcgc ctctcctccg agcagccagc gcctcgggac gcgatgagga ccttggcttg
421 cctgctgctc ctcggctgcg gatacctcgc ccatgttctg gccgaggaag ccgagatccc
481 ccgcgaggtg atcgagaggc tggcccgcgg tcagatccac agcatccggg acctccagcg
541 actcctggag atagactccg tagggagtga ggattctttg gacaccagcc tgagagctca
601 cggggtccac gccactaagc atgtgcccga gaagcggccc ctgcccattc ggaggaagag
661 aagcatcgag gaagctgtcc ccgctgtctg caagaccagg acggtcattt acgagattcc
721 tcggagtcag gtcgacccca cgtccgccaa cttcctgatc tggcccccgt gcgtggaggt
781 gaaacgctgc accggctgct gcaacacgag cagtgtcaag tgccagccct cccgcgtcca
841 ccaccgcagc gtcaaggtgg ccaaggtgga atacgtcagg aagaagccaa aattaaaaga
901 agtccaggtg aggttagagg agcatttgga gtgcgcctgc gcgaccacaa gcctgaatcc
961 ggattatcgg gaagaggaca cggatgtgag gtgaggatga gccgcagccc tttcctggga
1021 catggatgta catggcgtgt tacattcctg aacctactat gtacggtgct ttattgccag
1081 tgtgcggtct ttgttctcct ccgtgaaaaa ctgtgtccga gaacactcgg gagaacaaag
1141 agacagtgca catttgttta atgtgacatc aaagcaagta ttgtagcact cggtgaagca
1201 gtaagaagct tccttgtcaa aaagagagag agagagagag agagagaaaa caaaaccaca
1261 aatgacaaaa acaaaacgga ctcacaaaaa tatctaaact cgatgagatg gagggtcgcc
1321 ccgtgggatg gaagtgcaga ggtctcagca gactggattt ctgtccgggt ggtcacaggt
1381 gcttttttgc cgaggatgca gagcctgctt tgggaacgac tccagagggg tgctggtggg
1441 ctctgcaggg cccgcaggaa gcaggaatgt cttggaaacc gccacgcgaa ctttagaaac
1501 cacacctcct cgctgtagta tttaagccca tacagaaacc ttcctgagag ccttaagtgg
1561 tttttttttt tgtttttgtt ttgttttttt tttttttgtt tttttttttt tttttttttt
1621 ttacaccata aagtgattat taagcttcct tttactcttt ggctagcttt tttttttttt
1681 tttttttttt ttttttttaa ttatctcttg gatgacattt acaccgataa cacacaggct
1741 gctgtaactg tcaggacagt gcgacggtat ttttcctagc aagatgcaaa ctaatgagat
1801 gtattaaaat aaacatggta tacctaccta tgcatcattt cctaaatgtt tctggctttg
1861 tgtttctccc ttaccctgct ttatttgtta atttaagcca ttttgaaaga actatgcgtc
1921 aaccaatcgt acgccgtccc tgcggcacct gccccagagc ccgtttgtgg ctgagtgaca
1981 acttgttccc cgcagtgcac acctagaatg ctgtgttccc acgcggcacg tgagatgcat
2041 tgccgcttct gtctgtgttg ttggtgtgcc ctggtgccgt ggtggcggtc actccctctg
2101 ctgccagtgt ttggacagaa cccaaattct ttatttttgg taagatattg tgctttacct
2161 gtattaacag aaatgtgtgt gtgtggtttg tttttttgta aaggtgaagt ttgtatgttt
2221 acctaatatt acctgttttg tatacctgag agcctgctat gttcttcttt tgttgatcca
2281 aaattaaaaa aaaaatacca ccaac
＜110〉Attached Tongji Hospital, Tongji Univ.
＜120〉pulmonary thromboembolism related gene and application thereof
<160>142
<210>16
<211>3373
<212>DNA
＜213〉human (Homo sapiens)
<400>16
1 ggtggcaact tctcctcctg cggccgggag cggcctgcct gcctccctgc gcacccgcag
61 cctcccccgc tgcctcccta gggctcccct ccggccgcca gcgcccattt ttcattccct
121 agatagagat actttgcgcg cacacacata catacgcgcg caaaaaggaa aaaaaaaaaa
181 aaaagcccac cctccagcct cgctgcaaag agaaaaccgg agcagccgca gctcgcagct
241 cgcagctcgc agcccgcagc ccgcagagga cgcccagagc ggcgagcagg cgggcagacg
301 gaccgacgga ctcgcgccgc gtccacctgt cggccgggcc cagccgagcg cgcagcgggc
361 acgccgcgcg cgcggagcag ccgtgcccgc cgcccgggcc cgccgccagg gcgcacacgc
421 tcccgccccc ctacccggcc cgggcgggag tttgcacctc tccctgcccg ggtgctcgag
481 ctgccgttgc aaagccaact ttggaaaaag ttttttgggg gagacttggg ccttgaggtg
541 cccagctccg cgctttccga ttttgggggc ctttccagaa aatgttgcaa aaaagctaag
601 ccggcgggca gaggaaaacg cctgtagccg gcgagtgaag acgaaccatc gactgccgtg
661 ttccttttcc tcttggaggt tggagtcccc tgggcgcccc cacacggcta gacgcctcgg
721 ctggttcgcg acgcagcccc ccggccgtgg atgctgcact cgggctcggg atccgcccag
781 gtagccggcc tcggacccag gtcctgcgcc caggtcctcc cctgccccct agcgacggag
841 ccggggccgg gggcggcggc gccgggggca tgcgggtgag ccgcggctgc agaggcctga
901 gcgcctgatc gccgcggacc tgagccgagc ccacccccct ccccagcccc ccaccctggc
961 cgcgggggcg gcgcgctcga tctacgcgtc cggggccccg cggggccggg cccggagtcg
1021 gcatgaatcg ctgctgggcg ctcttcctgt ctctctgctg ctacctgcgt ctggtcagcg
1081 ccgaggggga ccccattccc gaggagcttt atgagatgct gagtgaccac tcgatccgct
1141 cctttgatga tctccaacgc ctgctgcacg gagaccccgg agaggaagat ggggccgagt
1201 tggacctgaa catgacccgc tcccactctg gaggcgagct ggagagcttg gctcgtggaa
1261 gaaggagcct gggttccctg accattgctg agccggccat gatcgccgag tgcaagacgc
1321 gcaccgaggt gttcgagatc tcccggcgcc tcatagaccg caccaacgcc aacttcctgg
1381 tgtggccgcc ctgtgtggag gtgcagcgct gctccggctg ctgcaacaac cgcaacgtgc
1441 agtgccgccc cacccaggtg cagctgcgac ctgtccaggt gagaaagatc gagattgtgc
1501 ggaagaagcc aatctttaag aaggccacgg tgacgctgga agaccacctg gcatgcaagt
1561 gtgagacagt ggcagctgca cggcctgtga cccgaagccc ggggggttcc caggagcagc
1621 gagccaaaac gccccaaact cgggtgacca ttcggacggt gcgagtccgc cggcccccca
1681 agggcaagca ccggaaattc aagcacacgc atgacaagac ggcactgaag gagacccttg
1741 gagcctaggg gcatcggcag gagagtgtgt gggcagggtt atttaatatg gtatttgctg
1801 tattgccccc atggggtcct tggagtgata atattgtttc cctcgtccgt ctgtctcgat
1861 gcctgattcg gacggccaat ggtgcttccc ccacccctcc acgtgtccgt ccacccttcc
1921 atcagcgggt ctcctcccag cggcctccgg tcttgcccag cagctcaaag aagaaaaaga
1981 aggactgaac tccatcgcca tcttcttccc ttaactccaa gaacttggga taagagtgtg
2041 agagagactg atggggtcgc tctttggggg aaacgggttc cttcccctgc acctggcctg
2101 ggccacacct gagcgctgtg gactgtcctg aggagccctg aggacctctc agcatagcct
2161 gcctgatccc tgaacccctg gccagctctg aggggaggca cctccaggca ggccaggctg
2221 cctcggactc catggctaag accacagacg ggcacacaga ctggagaaaa cccctcccac
2281 ggtgcccaaa caccagtcac ctcgtctccc tggtgcctct gtgcacagtg gcttcttttc
2341 gttttcgttt tgaagacgtg gactcctctt ggtgggtgtg gccagcacac caagtggctg
2401 ggtgccctct caggtgggtt agagatggag tttgctgttg aggtggtgta gatggtgacc
2461 tgggtatccc ctgcctcctg ccaccccttc ctccccatac tccactctga ttcacctctt
2521 cctctggttc ctttcatctc tctacctcca ccctgcattt tcctcttgtc ctggcccttc
2581 agtctgctcc accaaggggc tcttgaaccc cttattaagg ccccagatga ccccagtcac
2641 tcctctctag ggcagaagac tagaggccag ggcagcaagg gacctgctca tcatattcca
2701 acccagccac gactgccatg taaggttgtg cagggtgtgt actgcacaag gacattgtat
2761 gcagggagca ctgttcacat catagataaa gctgatttgt atatttatta tgacaatttc
2821 tggcagatgt aggtaaagag gaaaaggatc cttttcctaa ttcacacaaa gactccttgt
2881 ggactggctg tgcccctgat gcagcctgtg gctggagtgg ccaaatagga gggagactgt
2941 ggtaggggca gggaggcaac actgctgtcc acatgacctc catttcccaa agtcctctgc
3001 tccagcaact gcccttccag gtgggtgtgg gacacctggg agaaggtctc caagggaggg
3061 tgcagccctc ttgcccgcac ccctccctgc ttgcacactt ccccatcttt gatccttctg
3121 agctccacct ctggtggctc ctcctaggaa accagctcgt gggctgggaa tgggggagag
3181 aagggaaaag atccccaaga ccccctgggg tgggatctga gctcccacct cccttcccac
3241 ctactgcact ttcccccttc ccgccttcca aaacctgctt ccttcagttt gtaaagtcgg
3301 tgattatatt tttgggggct ttccttttat tttttaaatg taaaatttat ttatattccg
3361 tatttaaagt tgt
＜110〉Attached Tongji Hospital, Tongji Univ.
＜120〉pulmonary thromboembolism related gene and application thereof
<160>142
<210>17
<211>2653
<212>DNA
＜213〉human (Homo sapiens)
<400>17
1 atggccctgt ccactgagca tcctcccgcc acacagaaac ccgcccagcc ggggccaccg
61 accccacccc ctgcctggaa acttaaggag gccggagctg tggggagctc agagctgaga
121 tcctacagga gtccagggct ggagagaaaa cctctgcgag gaaagggaag gagcaagccg
181 tgaatttaag ggacgctgtg aagcaatcat ggatgcaatg aagagagggc tctgctgtgt
241 gctgctgctg tgtggagcag tcttcgtttc gcccagccag gaaatccatg cccgattcag
301 aagaggagcc agatcttacc aagtgatctg cagagatgaa aaaacgcaga tgatatacca
361 gcaacatcag tcatggctgc gccctgtgct cagaagcaac cgggtggaat attgctggtg
421 caacagtggc agggcacagt gccactcagt gcctgtcaaa agttgcagcg agccaaggtg
481 tttcaacggg ggcacctgcc agcaggccct gtacttctca gatttcgtgt gccagtgccc
541 cgaaggattt gctgggaagt gctgtgaaat agataccagg gccacgtgct acgaggacca
601 gggcatcagc tacaggggca cgtggagcac agcggagagt ggcgccgagt gcaccaactg
661 gaacagcagc gcgttggccc agaagcccta cagcgggcgg aggccagacg ccatcaggct
721 gggcctgggg aaccacaact actgcagaaa cccagatcga gactcaaagc cctggtgcta
781 cgtctttaag gcggggaagt acagctcaga gttctgcagc acccctgcct gctctgaggg
841 aaacagtgac tgctactttg ggaatgggtc agcctaccgt ggcacgcaca gcctcaccga
901 gtcgggtgcc tcctgcctcc cgtggaattc catgatcctg ataggcaagg tttacacagc
961 acagaacccc agtgcccagg cactgggcct gggcaaacat aattactgcc ggaatcctga
1021 tggggatgcc aagccctggt gccacgtgct gaagaaccgc aggctgacgt gggagtactg
1081 tgatgtgccc tcctgctcca cctgcggcct gagacagtac agccagcctc agtttcgcat
1141 caaaggaggg ctcttcgccg acatcgcctc ccacccctgg caggctgcca tctttgccaa
1201 gcacaggagg tcgcccggag agcggttcct gtgcgggggc atactcatca gctcctgctg
1261 gattctctct gccgcccact gcttccagga gaggtttccg ccccaccacc tgacggtgat
1321 cttgggcaga acataccggg tggtccctgg cgaggaggag cagaaatttg aagtcgaaaa
1381 atacattgtc cataaggaat tcgatgatga cacttacgac aatgacattg cgctgctgca
1441 gctgaaatcg gattcgtccc gctgtgccca ggagagcagc gtggtccgca ctgtgtgcct
1501 tcccccggcg gacctgcagc tgccggactg gacggagtgt gagctctccg gctacggcaa
1561 gcatgaggcc ttgtctcctt tctattcgga gcggctgaag gaggctcatg tcagactgta
1621 cccatccagc cgctgcacat cacaacattt acttaacaga acagtcaccg acaacatgct
1681 gtgtgctgga gacactcgga gcggcgggcc ccaggcaaac ttgcacgacg cctgccaggg
1741 cgattcggga ggccccctgg tgtgtctgaa cgatggccgc atgactttgg tgggcatcat
1801 cagctggggc ctgggctgtg gacagaagga tgtcccgggt gtgtacacca aggttaccaa
1861 ctacctagac tggattcgtg acaacatgcg accgtgacca ggaacacccg actcctcaaa
1921 agcaaatgag atcccgcctc ttcttcttca gaagacactg caaaggcgca gtgcttctct
1981 acagacttct ccagacccac cacaccgcag aagcgggacg agaccctaca ggagagggaa
2041 gagtgcattt tcccagatac ttcccatttt ggaagttttc aggacttggt ctgatttcag
2101 gatactctgt cagatgggaa gacatgaatg cacactagcc tctccaggaa tgcctcctcc
2161 ctgggcagaa agtggccatg ccaccctgtt ttcagctaaa gcccaacctc ctgacctgtc
2221 accgtgagca gctttggaaa caggaccaca aaaatgaaag catgtctcaa tagtaaaaga
2281 taacaagatc tttcaggaaa gacggattgc attagaaata gacagtatat ttatagtcac
2341 aagagcccag cagggcctca aagttggggc aggctggctg gcccgtcatg ttcctcaaaa
2401 gcacccttga cgtcaagtct ccttcccctt tccccactcc ctggctctca gaaggtattc
2461 cttttgtgta cagtgtgtaa agtgtaaatc ctttttcttt ataaacttta gagtagcatg
2521 agagaattgt atcatttgaa caactaggct tcagcatatt tatagcaatc catgttagtt
2581 tttactttct gttgccacaa ccctgtttta tactgtactt aataaattca gatatatttt
2641 tcacagtttt tcc
＜110〉Attached Tongji Hospital, Tongji Univ.
＜120〉pulmonary thromboembolism related gene and application thereof
<160>142
<210>18
<211>1254
<212>DNA
＜213〉human (Homo sapiens)
<400>18
1 atgaagacgg agcggccccg gcccaacacc ttcatcatcc gctgcctgca gtggaccact
61 gtcatcgaac gcaccttcca tgtggagact cctgaggagc gggaggagtg gacaaccgcc
121 atccagactg tggccgacgg cctcaagaag caggaggagg aggagatgga cttccggtcg
181 ggctcaccca gcgacaactc aggggccgaa gagatggagg tgtccctggc caagcccaag
241 caccgcgtga ccatgaacga gtttgagtac ctgaagctgc tgggcaaggg cactttcggc
301 aaggtgatcc tggtgaagga gaaggccaca gcgtactacg ccatgaagat cctcaagaag
361 gaagtcatcg tggccaagga cgaggtggcc cacacactca ccgagaaccg cgtccagcag
421 aactccaggc accccttcct cactcgcctg aagtactctt tccagaccca cgaccgcctc
481 tgctttgtca tggagtacgc caacgggggc gagctgttct tccacctgtc ccgggagcgt
541 gtgttcgccg aggaccgggc ccgcttctat ggcgctgaga ttgtgtcagc cctggactac
601 ctgcactcgg agaagaacgt ggtgtaccgg gacctcaagc tggagaacct catgctggac
661 aaggacgggc acattaagat cacagacttc gggctgtgca aggaggggat caaggacggt
721 gccaccatga agaccttttg cggcacacct gagtacctgg cccccgaggt gctggaggac
781 aatgactacg gccgtgcagt ggactggtgg gggctgggcg tggtcatgta cgagatgatg
841 tgcggtcgcc tgcccttcta caaccaggac catgagaagc tttttgagct catcctcatg
901 gaggagatcc gcttcccgcg cacgcttggt cccgaggcca agtccttgct ttcagggctg
961 ctcaagaagg accccaagca gaggcttggc gggggctccg aggacgccaa ggagatcatg
1021 cagcatcgct tctttaccgg tatcgtgtgg cagcacgtgt acgagaagaa gctcagccca
1081 cccttcaagc cccaggtcac gtcggagact gacaccaggt attttgatga ggagttcacg
1141 gcccagatga tcaccatcac accacctgac caagatgaca gcatggagtg tgtggacagc
1201 gagcgcaggc cccacttccc ccagttctcc tactcgccca gcgcgacggc ctga
＜110〉Attached Tongji Hospital, Tongji Univ.
＜120〉pulmonary thromboembolism related gene and application thereof
<160>142
<210>19
<211>1828
<212>DNA
＜213〉human (Homo sapiens)
<400>19
1 acttctccct agagcagggg tgtttgccag cagcctgcac tctcagaaat cagacttgag
61 tggccggaac ccttgagacc agaggcttac catgctgctc cctaggaggg ccaggaactg
121 ctgacgtgac cactggacag ttattcgtgt ctcttacaat taccaaacag aatggacaag
181 cttaataaaa taaccgtccc cgccagtcag aagttgaggc agcttcaaaa gatggtccat
241 gatattaaaa acaatgaagg tggaataatg aataaaatca aaaagctaaa agtcaaagca
301 cctccaagtg ttcctcgaag ggactacgct tcagagagcc ctgctgacga agaggagcag
361 tggtccgatg actttgacag cgactatgaa aatccagatg agcactcgga ctcagagatg
421 tacgtgatgc ccgccgagga gaacgctgat gacagctacg agccgcctcc agtagagcag
481 gaaaccaggc cggttcaccc agccctgccc ttcgccagag gcgagtatat agacaatcga
541 tcaagccaga ggcattcccc acccttcagc aagacacttc ccagtaagcc cagctggcct
601 tcagagaaag caaggctcac ctccaccctg ccggccctga ctgctttgca gaaacctcaa
661 gtcccaccca aacccaaagg cctccttgag gatgaggctg attatgtggt ccccgtggaa
721 gataatgatg aaaactatat tcatcccaca gaaagcagtt cacctccacc tgaaaaagct
781 cccatggtga atagatcaac caagccaaat tcctcaacgc ccgcctctcc tccaggaaca
841 gcttcaggtc gaaacagtgg ggcctgggaa accaagtcac ctccaccagc tgcaccatcc
901 ccgttgccac gggccgggaa aaaaccaacg acaccactga agacaactcc agttgcctct
961 caacagaatg cttcaagtgt ttgtgaagaa aaacctatac ctgctgaacg ccaccgaggg
1021 tcaagtcaca gacaagaagc tgtgcagtca ccagtgtttc ctcctgccca gaaacaaatc
1081 caccaaaaac ccatacctct gccaagattt acagaagggg gaaacccaac tgtggatggg
1141 cccctaccca gcttttcatc taattccact atttcagaac aggaagctgg cgttctctgc
1201 aagccatggt atgctggagc ctgtgatcga aagtctgctg aagaggcatt gcacagatca
1261 aacaaggatg gatcatttct tattcggaaa agctctggcc atgattccaa acaaccatat
1321 acactagttg tattctttaa taagcgagta tataatattc ctgtgcgatt tattgaagca
1381 acaaaacaat atgccttggg cagaaagaaa aatggtgaag agtactttgg aagtgttgct
1441 gaaatcatca ggaatcatca acatagtcct ttggttctta ttgacagtca gaataacaca
1501 aaagattcca ccagactgaa gtatgcagtt aaagtttcat aaagggggaa aaaaaagatc
1561 aataccattg cttcagacac tttcccaaag tttctccttt tgagaaaaag tcccaaaact
1621 tcatattttg gattatgaat catccagtaa taaaatggaa gatggagtca gctattgaag
1681 tggtcatcca tttcttttta agaagctcat gtggacttgt tctattgcct gacctgatga
1741 actgttaata tctggtgagg ttgagttatc atgctactaa tattttccaa ataaatattt
1801 ttatttttaa aaataaaaaa aaaaaaaa
＜110〉Attached Tongji Hospital, Tongji Univ.
＜120〉pulmonary thromboembolism related gene and application thereof
<160>142
<210>20
<211>1936
<212>DNA
＜213〉human (Homo sapiens)
<400>20
1 ccggagcctc ctggaccagg agaactgtaa cgcgagcccc gagccatggg cgaaaggcgg
61 ggccgagacg ggttgggggc gccgacggtt tcccggccct ggctgcagct tggaggagaa
121 gctgagcctg tgcttccgcc cctcggatcc gggcgccgag cccgaggacg gccgtgcggc
181 catcacggag ctcaactcct gcagggggac gagatttgga atgccctgac agataattat
241 gggaatgtga tgcctgtaga ctggaagtca tcgcatacta ggaccttgca cttgcttact
301 ctgaacctct cagaaaaagg ggtaagtgac agtttgctct ttgatacatc agatgatgaa
361 gagctgagag aacagctgga tatgcactca atcatcgtct cctgtgttaa tgatgaaccc
421 ctcttcacgg cagaccaggt tattgaagaa attgaagaaa tgatgcagga atcaccggac
481 ccagaagatg atgaaacccc tacacagtca gatcggcttt caatgctttc ccaggaaatt
541 caaactctca agaggtctag taccggcagt tatgaagaga gagtgaaaag gctctcagtg
601 tctgagttaa atgaaatcct ggaagaaatt gagactgcca ttaaggagta ctctgaggag
661 ctggtgcagc agttggcttt acgagatgaa ctggagtttg aaaaggaagt gaaaaacagc
721 tttatttctg ttcttattga agtgcaaaac aaacagaaag agcacaaaga aacagcaaaa
781 aagaaaaaga aactaaaaaa tggcagctct cagaatggga agaatgagag aagtcatatg
841 cccggcacat atttgactac agtcattcct tatgagaaaa aaaacggacc accgtctgtt
901 gaagatcttc aaatattaac aaaaattctt cgtgccatga aggaggacag tgaaaaagtt
961 ccgagcttgt taactgatta tattctgaaa gttctgtgtc ctacatagag cagcaacttt
1021 atctgcggtg ggctccaagc tagatttccg acagcattat tctgagagct ggctaccatt
1081 acccttcttg ctattggaaa ctcagcacat ttgaacttgg gtttgattca gtattaacag
1141 atcttgacta cactaattct ttatattata gaaccaacgg aaatatgggc actattttga
1201 attctagaga tggtttttgt taaatctact aataaactgt tctcttagta gattaagaga
1261 gagtaatatt aattgtgcat gtgcagttgt atttctcatt aactgacagt atgcccattt
1321 gtttttatgg ctttcttatc taaactgcac tgatgaacta gattaaagcc ttgggagatt
1381 tatactataa attcagtgat ggcaagaacc aacactgttt ttttgtgaga attgtcagtg
1441 taactattac ctaccagtat tgttcagaga gattgaaaca gaataaacgg gctgttcttg
1501 aagaagcaaa accagaatat gcattacttt ggtttaatac ttagtgctaa cattgaaact
1561 gttggtggtg atggattttg tagcttgctg cttgtttcac cactggtcaa attttaacca
1621 ttaaattgcc attcactttt agaatcttgt atttaagtaa gttttgattt tcaaatgttc
1681 tgcttcatgt gtctgtgaag aattgtactt ttttaaaagt gtgtgtcctc tgaggtgctt
1741 gagaaagtgt acactgcaga actgcccatt ctcattactg tgtcctattt tattcatgcc
1801 tgtgtgtttt tcttaagtat gaattctaga tacagctact tatggattca tcaatatcat
1861 gagcactttt gctggttcca gtcaaatcaa tggcatttaa taaatttttt aagaagtaaa
1921 aaaaaaaaaa aaaaaa
＜110〉Attached Tongji Hospital, Tongji Univ.
＜120〉pulmonary thromboembolism related gene and application thereof
<160>142
<210>21
<211>2443
<212>DNA
＜213〉human (Homo sapiens)
<400>21
1 cccccccccg ccgctgccgc ctctgcctgg gtcccttcgg ccgtacctct gcgtgggggc
61 tgcctccccg gctcccggtg cagacaccat gtacggattt gtgaatcacg ccctggagtt
121 gctggtgatc cgcaattacg gccccgaggt gtgggaagac atcaaaaaag aggcacagtt
181 agatgaagaa ggacagtttc ttgtcagaat aatatatgat gactccaaaa cttatgattt
241 ggttgctgct gcaagcaaag tcctcaatct caatgctgga gaaatcctcc aaatgtttgg
301 gaagatgttt ttcgtctttt gccaagaatc tggttatgat acaatcttgc gtgtcctggg
361 ctctaatgtc agagaatttc tacagaacct tgatgctctg cacgaccacc ttgctaccat
421 ctacccagga atgcgtgcac cttcctttag gtgcactgat gcagaaaagg gcaaaggact
481 cattttgcac tactactcag agagagaagg acttcaggat attgtcattg gaatcatcaa
541 aacagtggca caacaaatcc atggcactga aatagacatg aaggttattc agcaaagaaa
601 tgaagaatgt gatcatactc aatttttaat tgaagaaaaa gagtcaaaag aagaggattt
661 ttatgaagat cttgacagat ttgaagaaaa tggtacccag gaatcacgca tcagcccata
721 tacattctgc aaagcttttc cttttcatat aatatttgac cgggacctag tggtcactca
781 gtgtggcaat gctatataca gagttctccc ccagctccag cctgggaatt gcagccttct
841 gtctgtcttc tcgctggttc gtcctcatat tgatattagt ttccatggga tcctttctca
901 catcaatact gtttttgtat tgagaagcaa ggaaggattg ttggatgtgg agaaattaga
961 atgtgaggat gaactgactg ggactgagat cagctgctta cgtctcaagg gtcaaatgat
1021 ctacttacct gaagcagata gcatactttt tctatgttca ccaagtgtca tgaacctgga
1081 cgatttgaca aggagagggc tgtatctaag tgacatccct ctgcatgatg ccacgcgcga
1141 tcttgttctt ttgggagaac aatttagaga ggaatacaaa ctcacccaag aactggaaat
1201 cctcactgac aggctacagc tcacgttaag agccctggaa gatgaaaaga aaaagacaga
1261 cacattgctg tattctgtcc ttcctccgtc tgttgccaat gagctgcggc acaagcgtcc
1321 agtgcctgcc aaaagatatg acaatgtgac catcctcttt agtggcattg tgggcttcaa
1381 tgctttctgt agcaagcatg catctggaga aggagccatg aagatcgtca acctcctcaa
1441 cgacctctac accagatttg acacactgac tgattcccgg aaaaacccat ttgtttataa
1501 ggtggagact gttggtgaca agtatatgac agtgagtggt ttaccagagc catgcattca
1561 ccatgcacga tccatctgcc acctggcctt ggacatgatg gaaattgctg gccaggttca
1621 agtagatggt gaatctgttc agataacaat agggatacac actggagagg tagttacagg
1681 tgtcatagga cagcggatgc ctcgatactg tctttttggg aatactgtca acctcacaaa
1741 ccgaacagaa accacaggag aaaagggaaa aataaatgtg tctgaatata catacagatg
1801 tcttatgtct ccagaaaatt cagatccaca attccacttg gagcacagag gcccagtgtc
1861 catgaagggc aaaaaagaac caatgcaagt ttggtttcta tccagaaaaa atacaggaac
1921 agaggaaaca aagcaggatg atgactgaat cttggattat ggggtgaaga ggagtacaga
1981 ctaggttcca gttttctcct aacacgtgcc aagcccagga gcagttcttc cctatggata
2041 cagattttct tttgtccttg tccattaccc caagactttc ttctagatat atctctcact
2101 atccgttatt caaccttagc tctgctttct attacttttt aggctttagt atattatcta
2161 aagtttggct tttgatgtgg atgatgtgag cttcatgtgt cttaaaatct actacaagca
2221 ttacctaaca tggtgatctg caagtagtag gcacccaata aatatttgtt gaatttagtt
2281 aaatgaaact gaacagtgtt tggccatgtg tatatttata tcatgtttac caaatctgtt
2341 tagtgttcca catatatgta tatgtatatt ttaatgacta taatgtaata aagtttatat
2401 catgttggtg tatatcatta tagaaatcat tttctaaagg agt
＜110〉Attached Tongji Hospital, Tongji Univ.
＜120〉pulmonary thromboembolism related gene and application thereof
<160>142
<210>22
<211>1424
<212>DNA
＜213〉human (Homo sapiens)
<400>22
1 gaaggactgg ggaagactgg atgagaaggg tagaagaggg tgggtgtggg atggggaggg
61 gagagtggaa aggccctggg cagaccctgg cagaaggggc acggggcagg gtgtgagttc
121 cccactagca gggccaggtg agctatggtg ctgcacctac tgctcttctt gctgctgacc
181 ccacagggtg ggcacagctg ccaggggctg gagctggccc gggaacttgt tctggccaag
241 gtgagggccc tgttcttgga tgccttgggg ccccccgcgg tgaccaggga aggtggggac
301 cctggagtca ggcggctgcc ccgaagacat gccctggggg gcttcacaca caggggctct
361 gagcccgagg aagaggagga tgtctcccaa gccatccttt tcccagccac agatgccagc
421 tgtgaggaca agtcagctgc cagagggctg gcccaggagg ctgaggaggg cctcttcaga
481 tacatgttcc ggccatccca gcatacacgc agccgccagg tgacttcagc ccagctgtgg
541 ttccacaccg ggctggacag gcagggcaca gcagcctcca atagctctga gcccctgcta
601 ggcctgctgg cactgtcacc gggaggaccc gtggctgtgc ccatgtcttt gggccatgct
661 ccccctcact gggccgtgct gcacctggcc acctctgctc tctctctgct gacccacccc
721 gtcctggtgc tgctgctgcg ctgtcccctc tgtacctgct cagcccggcc tgaggccacg
781 cccttcctgg tggcccacac tcggaccaga ccacccagtg gaggggagag agcccgacgc
841 tcaactcccc tgatgtcctg gccttggtct ccctctgctc tgcgcctgct gcagaggcct
901 ccggaggaac cggctgccca tgccaactgc cacagagtag cactgaacat ctccttccag
961 gagctgggct gggaacggtg gatcgtgtac cctcccagtt tcatcttcca ctactgtcat
1021 ggtggttgtg ggctgcacat cccaccaaac ctgtcccttc cagtccctgg ggctccccct
1081 accccagccc agccctactc cttgctgcca ggggcccagc cctgctgtgc tgctctccca
1141 gggaccatga ggcccctaca tgtccgcacc acctcggatg gaggttactc tttcaagtat
1201 gagacagtgc ccaaccttct cacgcagcac tgtgcttgta tctaagggtg gggggtcttc
1261 cttcttaatc ccatggctgg tggccacgcc cccaccatca tcagctggga ggaaaggcag
1321 agttgggaaa tagatggctc ccactcctcc ctcctttcac ttctctgcct atgggctacc
1381 ctccccaccc cacttctatc tcaataaaga acacagtgca tatg
＜110〉Attached Tongji Hospital, Tongji Univ.
＜120〉pulmonary thromboembolism related gene and application thereof
<160>142
<210>23
<211>3334
<212>DNA
＜213〉human (Homo sapiens)
<400>23
1 attcctgcct gggaggttgt ggaagaagga agatggccag agctttgtgt ccactgcaag
61 ccctctggct tctggagtgg gtgctgctgc tcttgggacc ttgtgctgcc cctccagcct
121 gggccttgaa cctggaccca gtgcagctca ccttctatgc aggccccaat ggcagccagt
181 ttggattttc actggacttc cacaaggaca gccatgggag agtggccatc gtggtgggcg
241 ccccgcggac cctgggcccc agccaggagg agacgggcgg cgtgttcctg tgcccctgga
301 gggccgaggg cggccagtgc ccctcgctgc tctttgacct ccgtgatgag acccgaaatg
361 taggctccca aactttacaa accttcaagg cccgccaagg actgggggcg tcggtcgtca
421 gctggagcga cgtcattgtg gcctgcgccc cctggcagca ctggaacgtc ctagaaaaga
481 ctgaggaggc tgagaagacg cccgtaggta gctgcttttt ggctcagcca gagagcggcc
541 gccgcgccga gtactccccc tgtcgcggga acaccctgag ccgcatttac gtggaaaatg
601 attttagctg ggacaagcgt tactgtgaag cgggcttcag ctccgtggtc actcaggccg
661 gagagctggt gcttggggct cctggcggct attatttctt aggtctcctg gcccaggctc
721 cagttgcgga tattttctcg agttaccgcc caggcatcct tttgtggcac gtgtcctccc
781 agagcctctc ctttgactcc agcaacccag agtacttcga cggctactgg gggtactcgg
841 tggccgtggg cgagttcgac ggggatctca acactacaga atatgtcgtc ggtgccccca
901 cttggagctg gaccctggga gcggtggaaa ttttggattc ctactaccag aggctgcatc
961 ggctgcgcgc agagcagatg gcgtcgtatt ttgggcattc agtggctgtc actgacgtca
1021 acggggatgg gaggcatgat ctgctggtgg gcgctccact gtatatggag agccgggcag
1081 accgaaaact ggccgaagtg gggcgtgtgt atttgttcct gcagccgcga ggcccccacg
1141 cgctgggtgc ccccagcctc ctgctgactg gcacacagct ctatgggcga ttcggctctg
1201 ccatcgcacc cctgggcgac ctcgaccggg atggctacaa tgacattgca gtggctgccc
1261 cctacggggg tcccagtggc cggggccaag tgctggtgtt cctgggtcag agtgaggggc
1321 tgaggtcacg tccctcccag gtcctggaca gccccttccc cacaggctct gcctttggct
1381 tctcccttcg aggtgccgta gacatcgatg acaacggata cccagacctg atcgtgggag
1441 cttacggggc caaccaggtg gctgtgtaca gagctcagcc agtggtgaag gcctctgtcc
1501 agctactggt gcaagattca ctgaatcctg ctgtgaagag ctgtgtccta cctcagacca
1561 agacacccgt gagctgcttc aacatccaga tgtgtgttgg agccactggg cacaacattc
1621 ctcagaagct atccctaaat gccgagctgc agctggaccg gcagaagccc cgccagggcc
1681 ggcgggtgct gctgctgggc tctcaacagg caggcaccac cctgaacctg gatctgggcg
1741 gaaagcacag ccccatctgc cacaccacca tggccttcct tcgagatgag gcagacttcc
1801 gggacaagct gagccccatt gtgctcagcc tcaatgtgtc cctaccgccc acggaggctg
1861 gaatggcccc tgctgtcgtg ctgcatggag acacccatgt gcaggagcag acacgaatcg
1921 tcctggactc tggggaagat gacgtatgtg tgccccagct tcagctcact gccagcgtga
1981 cgggctcccc gctcctagtt ggggcagata atgtcctgga gctgcagatg gacgcagcca
2041 acgagggcga gggggcctat gaagcagagc tggccgtgca cctgccccag ggcgcccact
2101 acatgcgggc cctaagcaat gtcgagggct ttgagagact catctgtaat cagaagaagg
2161 agaatgagac cagggtggtg ctgtgtgagc tgggcaaccc catgaagaag aacgcccaga
2221 taggaatcgc gatgttggtg agcgtgggga atctggaaga ggctggggag tctgtgtcct
2281 tccagctgca gatacggagc aagaacagcc agaatccaaa cagcaagatt gtgctgctgg
2341 acgtgccggt ccgggcagag gcccaagtgg agctgcgagg gaactccttt ccagcctccc
2401 tggtggtggc agcagaagaa ggtgagaggg agcagaacag cttggacagc tggggaccca
2461 aagtggagca cacctatgag ctccacaaca atggccctgg gactgtgaat ggtcttcacc
2521 tcagcatcca ccttccggga cagtcccagc cctccgacct gctctacatc ctggatatac
2581 agccccaggg gggccttcag tgcttcccac agcctcctgt caaccctctc aaggtggact
2641 gggggctgcc catccccagc ccctccccca ttcacccggc ccatcacaag cgggatcgca
2701 gacagatctt cctgccagag cccgagcagc cctcgaggct tcaggatcca gttctcgtaa
2761 gctgcgactc ggcgccctgt actgtggtgc agtgtgacct gcaggagatg gcgcgcgggc
2821 agcgggccat ggtcacggtg ctggccttcc tgtggctgcc cagcctctac cagaggcctc
2881 tggatcagtt tgtgctgcag tcgcacgcat ggttcaacgt gtcctccctc ccctatgcgg
2941 tgcccccgct cagcctgccc cgaggggaag ctcaggtgtg gacacagctg ctccgggcct
3001 tggaggagag ggccattcca atctggtggg tgctggtggg tgtgctgggt ggcctgctgc
3061 tgctcaccat cctggtcctg gccatgtgga aggtcggctt cttcaagcgg aaccggccac
3121 ccctggaaga agatgatgaa gagggggagt gatggtgcag cctacactat tctagcagga
3181 gggttgggcg tgctacctgc accgcccctt ctccaacaag ttgcctccaa gctttgggtt
3241 ggagctgttc cattgggtcc tcttggtgtc gtttccctcc caacagagct gggctacccc
3301 ccctcctgct gcctaataaa gagactgagc cctg
＜110〉Attached Tongji Hospital, Tongji Univ.
＜120〉pulmonary thromboembolism related gene and application thereof
<160>142
<210>24
<211>11433
<212>DNA
＜213〉human (Homo sapiens)
<400>24
1 aggctgcttc gttgcacacc cgagaaagtt tcagccaaac ttcgggcggc ggctgaggcg
61 gcggccgagg agcggcggac tcggggcgcg gggagtcgag gcatttgcgc ctgggcttcg
121 gagcgtagcg ccagggcctg agcctttgaa gcaggaggag gggaggagag agtggggctc
181 ctctatcggg accccctccc catgtggatc tgcccaggcg gcggcggcgg cggcggagga
241 ggaggcgacc gagaagatgc ccgccctgcg ccccgctctg ctgtgggcgc tgctggcgct
301 ctggctgtgc tgcgcggccc ccgcgcatgc attgcagtgt cgagatggct atgaaccctg
361 tgtaaatgaa ggaatgtgtg ttacctacca caatggcaca ggatactgca aatgtccaga
421 aggcttcttg ggggaatatt gtcaacatcg agacccctgt gagaagaacc gctgccagaa
481 tggtgggact tgtgtggccc aggccatgct ggggaaagcc acgtgccgat gtgcctcagg
541 gtttacagga gaggactgcc agtactcaac atctcatcca tgctttgtgt ctcgaccctg
601 cctgaatggc ggcacatgcc atatgctcag ccgggatacc tatgagtgca cctgtcaagt
661 cgggtttaca ggtaaggagt gccaatggac ggatgcctgc ctgtctcatc cctgtgcaaa
721 tggaagtacc tgtaccactg tggccaacca gttctcctgc aaatgcctca caggcttcac
781 agggcagaaa tgtgagactg atgtcaatga gtgtgacatt ccaggacact gccagcatgg
841 tggcacctgc ctcaacctgc ctggttccta ccagtgccag tgccctcagg gcttcacagg
901 ccagtactgt gacagcctgt atgtgccctg tgcaccctca ccttgtgtca atggaggcac
961 ctgtcggcag actggtgact tcacttttga gtgcaactgc cttccaggtt ttgaagggag
1021 cacctgtgag aggaatattg atgactgccc taaccacagg tgtcagaatg gaggggtttg
1081 tgtggatggg gtcaacactt acaactgccg ctgtccccca caatggacag gacagttctg
1141 cacagaggat gtggatgaat gcctgctgca gcccaatgcc tgtcaaaatg ggggcacctg
1201 tgccaaccgc aatggaggct atggctgtgt atgtgtcaac ggctggagtg gagatgactg
1261 cagtgagaac attgatgatt gtgccttcgc ctcctgtact ccaggctcca cctgcatcga
1321 ccgtgtggcc tccttctctt gcatgtgccc agaggggaag gcaggtctcc tgtgtcatct
1381 ggatgatgca tgcatcagca atccttgcca caagggggca ctgtgtgaca ccaaccccct
1441 aaatgggcaa tatatttgca cctgcccaca aggctacaaa ggggctgact gcacagaaga
1501 tgtggatgaa tgtgccatgg ccaatagcaa tccttgtgag catgcaggaa aatgtgtgaa
1561 cacggatggc gccttccact gtgagtgtct gaagggttat gcaggacctc gttgtgagat
1621 ggacatcaat gagtgccatt cagacccctg ccagaatgat gctacctgtc tggataagat
1681 tggaggcttc acatgtctgt gcatgccagg tttcaaaggt gtgcattgtg aattagaaat
1741 aaatgaatgt cagagcaacc cttgtgtgaa caatgggcag tgtgtggata aagtcaatcg
1801 tttccagtgc ctgtgtcctc ctggtttcac tgggccagtt tgccagattg atattgatga
1861 ctgttccagt actccgtgtc tgaatggggc aaagtgtatc gatcacccga atggctatga
1921 atgccagtgt gccacaggtt tcactggtgt gttgtgtgag gagaacattg acaactgtga
1981 ccccgatcct tgccaccatg gtcagtgtca ggatggtatt gattcctaca cctgcatctg
2041 caatcccggg tacatgggcg ccatctgcag tgaccagatt gatgaatgtt acagcagccc
2101 ttgcctgaac gatggtcgct gcattgacct ggtcaatggc taccagtgca actgccagcc
2161 aggcacgtca ggggttaatt gtgaaattaa ttttgatgac tgtgcaagta acccttgtat
2221 ccatggaatc tgtatggatg gcattaatcg ctacagttgt gtctgctcac caggattcac
2281 agggcagaga tgtaacattg acattgatga gtgtgcctcc aatccctgtc gcaagggtgc
2341 aacatgtatc aacggtgtga atggtttccg ctgtatatgc cccgagggac cccatcaccc
2401 cagctgctac tcacaggtga acgaatgcct gagcaatccc tgcatccatg gaaactgtac
2461 tggaggtctc agtggatata agtgtctctg tgatgcaggc tgggttggca tcaactgtga
2521 agtggacaaa aatgaatgcc tttcgaatcc atgccagaat ggaggaactt gtgacaatct
2581 ggtgaatgga tacaggtgta cttgcaagaa gggctttaaa ggctataact gccaggtgaa
2641 tattgatgaa tgtgcctcaa atccatgcct gaaccaagga acctgctttg atgacataag
2701 tggctacact tgccactgtg tgctgccata cacaggcaag aattgtcaga cagtattggc
2761 tccctgttcc ccaaaccctt gtgagaatgc tgctgtttgc aaagagtcac caaattttga
2821 gagttatact tgcttgtgtg ctcctggctg gcaaggtcag cggtgtacca ttgacattga
2881 cgagtgtatc tccaagccct gcatgaacca tggtctctgc cataacaccc agggcagcta
2941 catgtgtgaa tgtccaccag gcttcagtgg tatggactgt gaggaggaca ttgatgactg
3001 ccttgccaat ccttgccaga atggaggttc ctgtatggat ggagtgaata ctttctcctg
3061 cctctgcctt ccgggtttca ctggggataa gtgccagaca gacatgaatg agtgtctgag
3121 tgaaccctgt aagaatggag ggacctgctc tgactacgtc aacagttaca cttgcaagtg
3181 ccaggcagga tttgatggag tccattgtga gaacaacatc aatgagtgca ctgagagctc
3241 ctgtttcaat ggtggcacat gtgttgatgg gattaactcc ttctcttgct tgtgccctgt
3301 gggtttcact ggatccttct gcctccatga gatcaatgaa tgcagctctc atccatgcct
3361 gaatgaggga acgtgtgttg atggcctggg tacctaccgc tgcagctgcc ccctgggcta
3421 cactgggaaa aactgtcaga ccctggtgaa tctctgcagt cggtctccat gtaaaaacaa
3481 aggtacttgc gttcagaaaa aagcagagtc ccagtgccta tgtccatctg gatgggctgg
3541 tgcctattgt gacgtgccca atgtctcttg tgacatagca gcctccagga gaggtgtgct
3601 tgttgaacac ttgtgccagc actcaggtgt ctgcatcaat gctggcaaca cgcattactg
3661 tcagtgcccc ctgggctata ctgggagcta ctgtgaggag caactcgatg agtgtgcgtc
3721 caacccctgc cagcacgggg caacatgcag tgacttcatt ggtggataca gatgcgagtg
3781 tgtcccaggc tatcagggtg tcaactgtga gtatgaagtg gatgagtgcc agaatcagcc
3841 ctgccagaat ggaggcacct gtattgacct tgtgaaccat ttcaagtgct cttgcccacc
3901 aggcactcgg ggcctactct gtgaagagaa cattgatgac tgtgcccggg gtccccattg
3961 ccttaatggt ggtcagtgca tggataggat tggaggctac agttgtcgct gcttgcctgg
4021 ctttgctggg gagcgttgtg agggagacat caacgagtgc ctctccaacc cctgcagctc
4081 tgagggcagc ctggactgta tacagctcac caatgactac ctgtgtgttt gccgtagtgc
4141 ctttactggc cggcactgtg aaaccttcgt cgatgtgtgt ccccagatgc cctgcctgaa
420t tggagggact tgtgctgtgg ccagtaacat gcctgatggt ttcatttgcc gttgtccccc
4261 gggattttcc ggggcaaggt gccagagcag ctgtggacaa gtgaaatgta ggaaggggga
4321 gcagtgtgtg cacaccgcct ctggaccccg ctgcttctgc cccagtcccc gggactgcga
4381 gtcaggctgt gccagtagcc cctgccagca cgggggcagc tgccaccctc agcgccagcc
4441 tccttattac tcctgccagt gtgccccacc attctcgggt agccgctgtg aactctacac
4501 ggcacccccc agcacccctc ctgccacctg tctgagccag tattgtgccg acaaagctcg
4561 ggatggcgtc tgtgatgagg cctgcaacag ccatgcctgc cagtgggatg ggggtgactg
4621 ttctctcacc atggagaacc cctgggccaa ctgctcctcc ccacttccct gctgggatta
4681 tatcgacaac cagtgtgatg agctgtgcaa cacggtcgag tgcctgtttg acaactttga
4741 atgccagggg aacagcaaga catgcaagta tgacaaatac tgtgcagacc acttcaaaga
4801 caaccactgt gaccaggggt gcaacagtga ggagtgtggt tgggatgggc tggactgtgc
4861 tgctgaccaa cctgagaacc tggcagaagg taccctggtt attgtggtat tgatgccacc
4921 tgaacaactg ctccaggatg ctcgcagctt cttgcgggca ctgggtaccc tgctccacac
4981 caacctgcgc attaagcggg actcccaggg ggaactcatg gtgtacccct attatggtga
5041 gaagtcagct gctatgaaga aacagaggat gacacgcaga tcccttcctg gtgaacaaga
5101 acaggaggtg gctggctcta aagtctttct ggaaattgac aaccgccagt gtgttcaaga
5161 ctcagaccac tgcttcaaga acacggatgc agcagcagct ctcctggcct ctcacgccat
5221 acaggggacc ctgtcatacc ctcttgtgtc tgtcgtcagt gaatccctga ctccagaacg
5281 cactcagctc ctctatctcc ttgctgttgc tgttgtcatc attctgttta ttattctgct
5341 gggggtaatc atggcaaaac gaaagcgtaa gcatggctct ctctggctgc ctgaaggttt
5401 cactcttcgc cgagatgcaa gcaatcacaa gcgtcgtgag ccagtgggac aggatgctgt
5461 ggggctgaaa aatctctcag tgcaagtctc agaagctaac ctaattggta ctggaacaag
5521 tgaacactgg gtcgatgatg aagggcccca gccaaagaaa gtaaaggctg aagatgaggc
5581 cttactctca gaagaagatg accccattga tcgacggcca tggacacagc agcaccttga
5641 agctgcagac atccgtagga caccatcgct ggctctcacc cctcctcagg cagagcagga
5701 ggtggatgtg ttagatgtga atgtccgtgg cccagatggc tgcaccccat tgatgttggc
5761 ttctctccga ggaggcagct cagatttgag tgatgaagat gaagatgcag aggactcttc
5821 tgctaacatc atcacagact tggtctacca gggtgccagc ctccaggccc agacagaccg
5881 gactggtgag atggccctgc accttgcagc ccgctactca cgggctgatg ctgccaagcg
5941 tctcctggat gcaggtgcag atgccaatgc ccaggacaac atgggccgct gtccactcca
6001 tgctgcagtg gcagctgatg cccaaggtgt cttccagatt ctgattcgca accgagtaac
6061 tgatctagat gccaggatga atgatggtac tacacccctg atcctggctg cccgcctggc
6121 tgtggaggga atggtggcag aactgatcaa ctgccaagcg gatgtgaatg cagtggatga
6181 ccatggaaaa tctgctcttc actgggcagc tgctgtcaat aatgtggagg caactctttt
6241 gttgttgaaa aatggggcca accgagacat gcaggacaac aaggaagaga cacctctgtt
6301 tcttgctgcc cgggagggga gctatgaagc agccaagatc ctgttagacc attttgccaa
6361 tcgagacatc acagaccata tggatcgtct tccccgggat gtggctcggg atcgcatgca
6421 ccatgacatt gtgcgccttc tggatgaata caatgtgacc ccaagccctc caggcaccgt
6481 gttgacttct gctctctcac ctgtcatctg tgggcccaac agatctttcc tcagcctgaa
6541 gcacacccca atgggcaaga agtctagacg gcccagtgcc aagagtacca tgcctactag
6601 cctccctaac cttgccaagg aggcaaagga tgccaagggt agtaggagga agaagtctct
6661 gagtgagaag gtccaactgt ctgagagttc agtaacttta tcccctgttg attccctaga
6721 atctcctcac acgtatgttt ccgacaccac atcctctcca atgattacat cccctgggat
6781 cttacaggcc tcacccaacc ctatgttggc cactgccgcc cctcctgccc cagtccatgc
6841 ccagcatgca ctatcttttt ctaaccttca tgaaatgcag cctttggcac atggggccag
6901 cactgtgctt ccctcagtga gccagttgct atcccaccac cacattgtgt ctccaggcag
6961 tggcagtgct ggaagcttga gtaggctcca tccagtccca gtcccagcag attggatgaa
7021 ccgcatggag gtgaatgaga cccagtacaa tgagatgttt ggtatggtcc tggctccagc
7081 tgagggcacc catcctggca tagctcccca gagcaggcca cctgaaggga agcacataac
7141 cacccctcgg gagcccttgc cccccattgt gactttccag ctcatcccta aaggcagtat
7201 tgcccaacca gcgggggctc cccagcctca gtccacctgc cctccagctg ttgcgggccc
7261 cctgcccacc atgtaccaga ttccagaaat ggcccgtttg cccagtgtgg ctttccccac
7321 tgccatgatg ccccagcagg acgggcaggt agctcagacc attctcccag cctatcatcc
7381 tttcccagcc tctgtgggca agtaccccac acccccttca cagcacagtt atgcttcctc
7441 aaatgctgct gagcgaacac ccagtcacag tggtcacctc cagggtgagc atccctacct
7501 gacaccatcc ccagagtctc ctgaccagtg gtcaagttca tcaccccact ctgcttctga
7561 ctggtcagat gtgaccacca gccctacccc tgggggtgct ggaggaggtc agcggggacc
7621 tgggacacac atgtctgagc caccacacaa caacatgcag gtttatgcgt gagagagtcc
7681 acctccagtg tagagacata actgactttt gtaaatgctg ctgaggaaca aatgaaggtc
7741 atccgggaga gaaatgaaga aatctctgga gccagcttct agaggtagga aagagaagat
7801 gttcttattc agataatgca agagaagcaa ttcgtcagtt tcactgggta tctgcaaggc
7861 ttattgatta ttctaatcta ataagacaag tttgtggaaa tgcaagatga atacaagcct
7921 tgggtccatg tttactctct tctatttgga gaataagatg gatgcttatt gaagcccaga
7981 cattcttgca gcttggactg cattttaagc cctgcaggct tctgccatat ccatgagaag
8041 attctacact agcgtcctgt tgggaattat gccctggaat tctgcctgaa ttgacctacg
8101 catctcctcc tccttggaca ttcttttgtc ttcatttggt gcttttggtt ttgcacctct
8161 ccgtgattgt agccctacca gcatgttata gggcaagacc tttgtgcttt tgatcattct
8221 ggcccatgaa agcaactttg gtctcctttc ccctcctgtc ttcccggtat cccttggagt
8281 ctcacaaggt ttactttggt atggttctca gcacaaacct ttcaagtatg ttgtttcttt
8341 ggaaaatgga catactgtat tgtgttctcc tgcatatatc attcctggag agagaagggg
8401 agaagaatac ttttcttcaa caaattttgg gggcaggaga tcccttcaag aggctgcacc
8461 ttaatttttc ttgtctgtgt gcaggtcttc atataaactt taccaggaag aagggtgtga
8521 gtttgttgtt tttctgtgta tgggcctggt cagtgtaaag ttttatcctt gatagtctag
8581 ttactatgac cctccccact tttttaaaac cagaaaaagg tttggaatgt tggaatgacc
8641 aagagacaag ttaactcgtg caagagccag ttacccaccc acaggtcccc ctacttcctg
8701 ccaagcattc cattgactgc ctgtatggaa cacatttgtc ccagatctga gcattctagg
8761 cctgtttcac tcactcaccc agcatatgaa actagtctta actgttgagc ctttcctttc
8821 atatccacag aagacactgt ctcaaatgtt gtacccttgc catttaggac tgaactttcc
8881 ttagcccaag ggacccagtg acagttgtct tccgtttgtc agatgatcag tctctactga
8941 ttatcttgct gcttaaaggc ctgctcacca atctttcttt cacaccgtgt ggtccgtgtt
9001 actggtatac ccagtatgtt ctcactgaag acatggactt tatatgttca agtgcaggaa
9061 ttggaaagtt ggacttgttt tctatgatcc aaaacagccc tataagaagg ttggaaaagg
9121 aggaactata tagcagcctt tgctattttc tgctaccatt tcttttcctc tgaagcggcc
9181 atgacattcc ctttggcaac taacgtagaa actcaacaga acattttcct ttcctagagt
9241 caccttttag atgataatgg acaactatag acttgctcat tgttcagact gattgcccct
9301 cacctgaatc cactctctgt attcatgctc ttggcaattt ctttgacttt cttttaaggg
9361 cagaagcatt ttagttaatt gtagataaag aatagttttc ttcctcttct ccttgggcca
9421 gttaataatt ggtccatggc tacactgcaa cttccgtcca gtgctgtgat gcccatgaca
9481 cctgcaaaat aagttctgcc tgggcatttt gtagatatta acaggtgaat tcccgactct
9541 tttggtttga atgacagttc tcattccttc tatggctgca agtatgcatc agtgcttccc
9601 acttacctga tttgtctgtc ggtggcccca tatggaaacc ctgcgtgtct gttggcataa
9661 tagtttacaa atggtttttt cagtcctatc caaatttatt gaaccaacaa aaataattac
9721 ttctgccctg agataagcag attaagtttg ttcattctct gctttattct ctccatgtgg
9781 caacattctg tcagcctctt tcatagtgtg caaacatttt atcattctaa atggtgactc
9841 tctgcccttg gacccattta ttattcacag atggggagaa cctatctgca tggacctctg
9901 tggaccacag cgtacctgcc cctttctgcc ctcctgctcc agccccactt ctgaaagtat
9961 cagctactga tccagccact ggatatttta tatcctccct tttccttaag cacaatgtca
10021 gaccaaattg cttgtttctt tttcttggac tactttaatt tggatccttt gggtttggag
10081 aaagggaatg tgaaagctgt cattacagac aacaggtttc agtgatgagg aggacaacac
10141 tgcctttcaa actttttact gatctcttag attttaagaa ctcttgaatt gtgtggtatc
10201 taataaaagg gaaggtaaga tggataatca ctttctcatt tgggttctga attggagact
10261 cagtttttat gagacacatc ttttatgcca tgtatagatc ctcccctgct atttttggtt
10321 tatttttatt gttataaatg ctttctttct ttgactcctc ttctgcctgc ctttggggat
10381 aggttttttt gtttgtttat ttgcttcctc tgttttgttt taagcatcat tttcttatgt
10441 gaggtgggga agggaaaggt atgagggaaa gagagtctga gaattaaaat attttagtat
10501 aagcaattgg ctgtgatgct caaatccatt gcatcctctt attgaatttg ccaatttgta
10561 atttttgcat aataaagaac caaaggtgta atgttttgtt gagaggtggt ttagggattt
10621 tggccctaac caatacattg aatgtatgat gactatttgg gaggacacat ttatgtaccc
10681 agaggccccc actaataagt ggtactatgg ttacttcctt gtgtacattt ctcttaaaag
10741 tgatattata tctgtttgta tgagaaaccc agtaaccaat aaaatgaccg catattcctg
10801 actaaacgta gtaaggaaaa tgcacacttt gtttttactt ttccgtttca ttctaaaggt
10861 agttaagatg aaatttatat gaaagcattt ttatcacaaa ataaaaaagg tttgccaagc
10921 tcagtggtgt tgtatttttt attttccaat actgcatcca tggcctggca gtgttacctc
10981 atgatgtcat aatttgctga gagagcaaat tttcttttct ttctgaatcc cacaaagcct
11041 agcaccaaac ttcttttttt cttcctttaa ttagatcata aataaatgat cctggggaaa
11101 aagcatctgt caaataggaa acatcacaaa actgagcact cttctgtgca ctagccatag
11161 ctggtgacaa acagatggtt gctcagggac aaggtgcctt ccaatggaaa tgcgaagtag
11221 ttgctatagc aagaattggg aactgggata taagtcataa tattaattat gctgttatgt
11281 aaatgattgg tttgtaacat tccttaagtg aaatttgtgt agaacttaat atacaggatt
11341 ataaaataat attttgtgta taaatttgtt ataagttcac attcatacat ttatttataa
11401 agtcagtgag atatttgaac atgaaaaaaa aaa
＜110〉Attached Tongji Hospital, Tongji Univ.
＜120〉pulmonary thromboembolism related gene and application thereof
<160>142
<210>25
<211>6762
<212>DNA
＜213〉human (Homo sapiens)
<400>25
1 agacgtgagg cttgcagcag gccgaggagg aagaagaggg gcagtgggag cagaggaggt
61 ggctcctgcc ccagtgagag ctctgagggt ccctgcctga agagggacag ggaccggggc
121 ttggagaagg ggctgtggaa tgcagccccc ttcactgctg ctgctgctgc tgctgctgct
181 gctgctatgt gtctcagtgg tcagacccag agggctgctg tgtgggagtt tcccagaacc
241 ctgtgccaat ggaggcacct gcctgagcct gtctctggga caagggacct gccagtgtgc
301 ccctggcttc ctgggtgaga cgtgccagtt tcctgacccc tgccagaacg cccagctctg
361 ccaaaatgga ggcagctgcc aagccctgct tcccgctccc ctagggctcc ccagctctcc
421 ctctccattg agacccagct tcttgtgcac ttgcctccct ggcttcactg gtgagagatg
481 ccaggccaag cttgaagacc cttgtcctcc ctccttctgt tccaaaaggg gccgctgcca
541 catccaggcc tcgggccgcc cacagtgctc ctgcatgcct ggatggacag gtgagcagtg
601 ccagcttcgg gacttctgtt cagccaaccc atgtgttaat ggaggggtgt gtctggccac
661 atacccccag atccagtgcc actgcccacc gggcttcgag ggccatgcct gtgaacgtga
721 tgtcaacgag tgcttccagg acccaggacc ctgccccaaa ggcacctcct gccataacac
781 cctgggctcc ttccagtgcc tctgccctgt ggggcaggag ggtccacgtt gtgagctgcg
841 ggcaggaccc tgccctccta ggggctgttc gaatgggggc acctgccagc tgatgccaga
901 gaaagactcc acctttcacc tctgcctctg tcccccaggt ttcataggcc cagactgtga
961 ggtgaatcca gacaactgtg tcagccacca gtgtcagaat gggggcactt gccaggatgg
1021 gctggacacc tacacctgcc tctgcccaga aacctggaca ggctgggact gctccgaaga
1081 tgtggatgag tgtgagaccc agggtccccc tcactgcaga aacgggggca cctgccagaa
1141 ctctgctggt agctttcact gcgtgtgtgt gagtggctgg ggcggcacaa gctgtgagga
1201 gaacctggat gactgtattg ctgccacctg tgccccggga tccacctgca ttgaccgggt
1261 gggctctttc tcctgcctct gcccacctgg acgcacagga ctcctgtgcc acttggaaga
1321 catgtgtctg agccagccgt gccatgggga tgcccaatgc agcaccaacc ccctcacagg
1381 ctccacactc tgcctgtgtc agcctggcta ttcggggccc acctgccacc aggacctgga
1441 cgagtgtctg atggcccagc aaggcccaag tccctgtgaa catggcggtt cctgcctcaa
1501 cactcctggc tccttcaact gcctctgtcc acctggctac acaggctccc gttgtgaggc
1561 tgatcacaat gagtgcctct cccagccctg ccacccagga agcacctgtc tggacctact
1621 tgccaccttc cactgcctct gcccgccagg cttagaaggg cagctctgtg aggtggagac
1681 caacgagtgt gcctcagctc cctgcctgaa ccacgcggat tgccatgacc tgctcaacgg
1741 cttccagtgc atctgcctgc ctggattctc cggcacccga tgtgaggagg atatcgatga
1801 gtgcagaagc tctccctgtg ccaatggtgg gcagtgccag gaccagcctg gagccttcca
1861 ctgcaagtgt ctcccaggct ttgaagggcc acgctgtcaa acagaggtgg atgagtgcct
1921 gagtgaccca tgtcccgttg gagccagctg ccttgatctt ccaggagcct tcttttgcct
1981 ctgcccctct ggtttcacag gccagctctg tgaggttccc ctgtgtgctc ccaacctgtg
2041 ccagcccaag cagatatgta aggaccagaa agacaaggcc aactgcctct gtcctgatgg
2101 aagccctggc tgtgccccac ctgaggacaa ctgcacctgc caccacgggc actgccagag
2161 atcctcatgt gtgtgtgacg tgggttggac ggggccagag tgtgaggcag agctaggggg
2221 ctgcatctct gcaccctgtg cccatggggg gacctgctac ccccagccct ctggctacaa
2281 ctgcacctgc cctacaggct acacaggacc cacctgtagt gaggagatga cagcttgtca
2341 ctcagggcca tgtctcaatg gcggctcctg caaccctagc cctggaggct actactgcac
2401 ctgccctcca agccacacag ggccccagtg ccaaaccagc actgactact gtgtgtctgc
2461 cccgtgcttc aatgggggta cctgtgtgaa caggcctggc accttctcct gcctctgtgc
2521 catgggcttc cagggcccgc gctgtgaggg aaagctccgc cccagctgtg cagacagccc
2581 ctgtaggaat agggcaacct gccaggacag ccctcagggt ccccgctgcc tctgccccac
2641 tggctacacc ggaggcagct gccagactct gatggactta tgtgcccaga agccctgccc
2701 acgcaattcc cactgcctcc agactgggcc ctccttccac tgcttgtgcc tccagggatg
2761 gaccgggcct ctctgcaacc ttccactgtc ctcctgccag aaggctgcac tgagccaagg
2821 catagacgtc tcttcccttt gccacaatgg aggcctctgt gtcgacagcg gcccctccta
2881 tttctgccac tgcccccctg gattccaagg cagcctgtgc caggatcacg tgaacccatg
2941 tgagtccagg ccttgccaga acggggccac ctgcatggcc cagcccagtg ggtatctctg
3001 ccagtgtgcc ccaggctacg atggacagaa ctgctcaaag gaactcgatg cttgtcagtc
3061 ccaaccctgt cacaaccatg gaacctgtac tcccaaacct ggaggattcc actgtgcctg
3121 ccctccaggc tttgtggggc tacgctgtga gggagacgtg gacgagtgtc tggaccagcc
3181 ctgccacccc acaggcactg cagcctgcca ctctctggcc aatgccttct actgccagtg
3241 tctgcctgga cacacaggcc agtggtgtga ggtggagata gacccctgcc acagccaacc
3301 ctgctttcat ggagggacct gtgaggccac agcaggatca cccctgggtt tcatctgcca
3361 ctgccccaag ggttttgaag gccccacctg cagccacagg gccccttcct gcggcttcca
3421 tcactgccac cacggaggcc tgtgtctgcc ctcccctaag ccaggcttac caccacgctg
3481 tgcctgcctc agtggctatg ggggtcctga ctgcctgacc ccaccagcfc ctaaaggctg
3541 tggccctccc tccccatgcc tatacaatgg cagctgctca gagaccacgg gcttgggggg
3601 cccaggcttt cgatgctcct gccctcacag ctctccaggg ccccggtgtc agaaacccgg
3661 agccaagggg tgtgagggca gaagtggaga tggggcctgc gatgctggct gcagtggccc
3721 gggaggaaac tgggatggag gggactgctc tctgggagtc ccagacccct ggaagggctg
3781 cccctcccac tctcggtgct ggcttctctt ccgggacggg cagtgccacc cacagtgtga
3841 ctctgaagag tgtctgtttg atggctacga ctgtgagacc cctccagcct gcactccagc
3901 ctatgaccag tactgccatg atcacttcca caacgggcac tgtgagaaag gctgcaacac
3961 tgcagagtgt ggctgggatg gaggtgactg caggcctgaa gatggggacc cagagtgggg
4021 gccctccctg gccctgctgg tggtactgag ccccccagcc ctagaccagc agctgtttgc
4081 cctggcccgg gtgctgtccc tgactctgag ggtaggactc tgggtaagga aggatcgtga
4141 tggcagggac atggtgtacc cctatcctgg ggcccgggct gaagaaaagc taggaggaac
4201 tcgggacccc acctatcagg agagagcagc ccctcaaacg cagcccctgg gcaaggagac
4261 cgactccctc agtgctgggt ttgtggtggt catgggtgtg gatttgtccc gctgtggccc
4321 tgaccacccg gcatcccgct gtccctggga ccctgggctt ctactccgct tccttgctgc
4381 gatggctgca gtgggagccc tggagcccct gctgcctgga ccactgctgg ctgtccaccc
4441 tcatgcaggg accgcacccc ctgccaacca gcttccctgg cctgtgctgt gctccccagt
4501 ggccggggtg attctcctgg ccctaggggc tcttctcgtc ctccagctca tccggcgtcg
4561 acgccgagag catggagctc tctggctgcc ccctggtttc actcgacggc ctcggactca
4621 gtcagctccc caccgacgcc ggcccccact aggcgaggac agcattggtc tcaaggcact
4681 gaagccaaag gcagaagttg atgaggatgg agttgtgatg tgctcaggcc ctgaggaggg
4741 agaggaggtg ggccaggctg aagaaacagg cccaccctcc acgtgccagc tctggtctct
4801 gagtggtggc tgtggggcgc tccctcaggc agccatgcta actcctcccc aggaatctga
4861 gatggaagcc cctgacctgg acacccgtgg acctgatggg gtgacacccc tgatgtcagc
4921 agtttgctgt ggggaagtac agtccgggac cttccaaggg gcatggttgg gatgtcctga
4981 gccctgggaa cctctgctgg atggaggggc ctgtccccag gctcacaccg tgggcactgg
5041 ggagaccccc ctgcacctgg ctgcccgatt ctcccggcca accgctgccc gccgcctcct
5101 tgaggctgga gccaacccca accagccaga ccgggcaggg cgcacacccc ttcatgctgc
5161 tgtggctgct gatgctcggg aggtctgcca gcttctgctc cgtagcagac aaactgcagt
5221 ggacgctcgc acagaggacg ggaccacacc cttgatgctg gctgccaggc tggcggtgga
5281 agacctggtt gaagaactga ttgcagccca agcagacgtg ggggccagag ataaatgggg
5341 gaaaactgcg ctgcactggg ctgctgccgt gaacaacgcc cgagccgccc gctcgcttct
5401 ccaggccgga gccgataaag atgcccagga caacagggag cagacgccgc tattcctggc
5461 ggcgcgggaa ggagcggtgg aagtagccca gctactgctg gggctggggg cagcccgaga
5521 gctgcgggac caggctgggc tagcgccggc ggacgtcgct caccaacgta accactggga
5581 tctgctgacg ctgctggaag gggctgggcc accagaggcc cgtcacaaag ccacgccggg
5641 ccgcgaggct gggcccttcc cgcgcgcacg gacggtgtca gtaagcgtgc ccccgcatgg
5701 gggcggggct ctgccgcgct gccggacgct gtcagccgga gcaggccctc gtgggggcgg
5761 agcttgtctg caggctcgga cttggtccgt agacttggct gcgcgggggg gcggggccta
5821 ttctcattgc cggagcctct cgggagtagg agcaggagga ggcccgaccc ctcgcggccg
5881 taggttttct gcaggcatgc gcgggcctcg gcccaaccct gcgataatgc gaggaagata
5941 cggagtggct gccgggcgcg gaggcagggt ctcaacggat gactggccct gtgattgggt
6001 ggccctggga gcttgcggtt ctgcctccaa cattccgatc ccgcctcctt gccttactcc
6061 gtccccggag cggggatcac ctcaacttga ctgtggtccc ccagccctcc aagaaatgcc
6121 cataaaccaa ggaggagagg gtaaaaaata gaagaataca tggtagggag gaattccaaa
6181 aatgattacc cattaaaagg caggctggaa ggccttcctg gttttaagat ggatccccca
6241 aaatgaaggg ttgtgagttt agtttctctc ctaaaatgaa tgtatgccca ccagagcaga
6301 catcttccac gtggagaagc tgcagctctg gaaagagggt ttaagatgct aggatgaggc
6361 aggcccagtc ctcctccaga aaataagaca ggccacagga gggcagagtg gagtggaaat
6421 acccctaagt tggaaccaag aattgcaggc atatgggatg taagatgttc tttcctatat
6481 atggtttcca aagggtgccc ctatgatcca ttgtccccac tgcccacaaa tggctgacaa
6541 atatttattg ggcacctact atgtgccagg cactgtgtag gtgctgaaaa gtggccaagg
6601 gccacccccg ctgatgactc cttgcattcc ctcccctcac aacaaagaac tccactgtgg
6661 ggatgaagcg cttcttctag ccactgctat cgctatttaa gaaccctaaa tctgtcaccc
6721 ataataaagc tgatttgaag tgttaaaaaa aaaaaaaaaa aa
＜110〉Attached Tongji Hospital, Tongji Univ.
＜120〉pulmonary thromboembolism related gene and application thereof
<160>142
<210>26
<211>581
<212>DNA
＜213〉human (Homo sapiens)
<400>26
1 ttcaccaatg tttatatcaa aaactttggg gaagaggtgg atgatgagag tctgaaagag
61 ctattcagtc agtttggtaa gaccctaagt gtcaaggtga tgagagatcc caatgggaaa
121 tccaaaggct ttggctttgt gagttacgaa aaacacgagg atgccaataa ggctgtggaa
181 gagatgaatg gaaaagaaat aagtggtaaa atcatatttg taggccgtgc acaaaagaaa
241 gtagaacggc aggcagagtt aaaacggaaa tttgaacagt tgaaacagga gagaattagt
301 cgatatcagg gggtgaatct ctacattaag aacttggatg acactattga tgatgagaaa
361 ttaaggaaag aattttctcc ttttggatca attaccagtg ctaaggtaat gctggaggat
421 ggaagaagca aagggtttgg cttcgtctgc ttctcatctc ctgaagaagc aaccaaagca
481 gtcactgaga tgaatggacg cattgtgggc tccaagccac tatatgttgc cctggcccag
541 aggaaggaag agagaaaggc tcacctgacc aaccccgaat t
＜110〉Attached Tongji Hospital, Tongji Univ.
＜120〉pulmonary thromboembolism related gene and application thereof
<160>142
<210>27
<211>2966
<212>DNA
＜213〉human (Homo sapiens)
<400>27
1 cgcccgagcc gcgcgcggag ctgccggggg ctccttagca cccgggcgcc ggggccctcg
61 cccttccgca gccttcactc cagccctctg ctcccgcacg ccatgaagtc gccgttctac
121 cgctgccaga acaccacctc tgtggaaaaa ggcaactcgg cggtgatggg cggggtgctc
181 ttcagcaccg gcctcctggg caacctgctg gccctggggc tgctggcgcg ctcggggctg
241 gggtggtgct cgcggcgtcc actgcgcccg ctgccctcgg tcttctacat gctggtgtgt
301 ggcctgacgg tcaccgactt gctgggcaag tgcctcctaa gcccggtggt gctggctgcc
361 tacgctcaga accggagtct gcgggtgctt gcgcccgcat tggacaactc gttgtgccaa
421 gccttcgcct tcttcatgtc cttctttggg ctctcctcga cactgcaact cctggccatg
481 gcactggagt gctggctctc cctagggcac cctttcttct accgacggca catcaccctg
541 cgcctgggcg cactggtggc cccggtggtg agcgccttct ccctggcttt ctgcgcgcta
601 cctttcatgg gcttcgggaa gttcgtgcag tactgccccg gcacctggtg ctttatccag
661 atggtccacg aggagggctc gctgtcggtg ctggggtact ctgtgctcta ctccagcctc
721 atggcgctgc tggtcctcgc caccgtgctg tgcaacctcg gcgccatgcg caacctctat
781 gcgatgcacc ggcggctgca gcggcacccg cgctcctgca ccagggactg tgccgagccg
841 cgcgcggacg ggagggaagc gtcccctcag cccctggagg agctggatca cctcctgctg
901 ctggcgctga tgaccgtgct cttcactatg tgttctctgc ccgtaattta tcgcgcttac
961 tatggagcat ttaaggatgt caaggagaaa aacaggacct ctgaagaagc agaagacctc
1021 cgagccttgc gatttctatc tgtgatttca attgtggacc cttggatttt tatcattttc
1081 agatctccag tatttcggat attttttcac aagattttca ttagacctct taggtacagg
1141 agccggtgca gcaattccac taacatggaa tccagtctgt gacagtgttt ttcactctgt
1201 ggtaagctga ggaatatgtc acattttcag tcaaagaacc atgattaaaa aaaaaaagac
1261 aacttacaat ttaaatcctt aaaagttacc tcccataaca aaagcatgta tatgtatttt
1321 caaaagtatt tgatatctta acaatgtgtt accattctat agtcatgaac cccttcagtg
1381 cattttcatt tttttattaa cagcaactaa aattttatat attgtaacca gtgttaaaag
1441 tcttaaaaaa caatggtatt aattgtccct acatttgtgc ttggtggccc tatttttttt
1501 ttttagagag gccttgagac atacaggtct tttaaaatac agtagaaaca ccactgttta
1561 cgattatacg atggacattc ataaaaagca taatttctta ccctattcat tttttggtga
1621 aacctgattc attgatttta tatcattgcc gatgtttagt tcatttcttt gccaattgat
1681 ctaagcatag cctgaattat gatgttcctc agagaagtga ggtgggaaat atgaccaggt
1741 caggcagttg gaggggcttc cccagccacc atcggggagt acttgctgcc tcaggtggag
1801 acctgaagct gtaactagat gcagagcaag atatgactat agcccacaac ccaaagaagc
1861 aaaaattcgt ttttatcttt tgaaatccag tttcttttgt attgagtcaa gggtgtcagt
1921 aggaatcaaa agttgggggt gggttgcaaa atgttctttc agtttttaga acctccattt
1981 tataaaagaa ttatcctatc aatggattct ttagtggaag gatttatgct tctttgaaaa
2041 ccagtgtgtg actcactgta gagccatgtt tactgtttga ctgtgtggca caggggggca
2101 tttggcacag caaaaagccc acccaggact tagcctcagt tgacgatagt aacaatggcc
2161 ttaacatcta ccttaacagc tacctattac agccgtattc tgctgtccgt ggagacggta
2221 agatcttagg ttccaagatt ttacttcaaa ttacaccttc aaaactggag cagcatatag
2281 ccgaaaagga gcacaactga gcactttaat agtaatttaa aagttttcaa gggtcagcaa
2341 tatgatgact gaaagggaaa agtggaggaa acgcagctgc aactgaagcg gagactctaa
2401 acccagcttg caggtaagag ctttcacctt tggtaaaaga acagctgggg aggttcaagg
2461 ggtttcagca tctctggagt tcctttgtat ctgacaatct caggactcca aggtgcaaag
2521 cctgctgcat ttgcgtgatc tcaagacctc cagccagaag tcccttccaa atataagagt
2581 actcatgttt atttatttcc aactgagcag caacctcctt tgtttcactt atgttttttc
2641 cagtatctga gataatataa agctgggtaa ttttttatgt aattttttgg tatagcaaaa
2701 ctgtgaaaaa gccaaattag gcatacaagg agtatgattt aacagtatga catgatgaaa
2761 aaaatacagt tgtttttgaa atttaacttt tgtttgtacc ttcaatgtgt aagtacatgc
2821 atgttttatt gtcagaggaa gaacatgttt tttgtattct ttttttggag aggtgtgtta
2881 ggataattgt ccagttaatt tgaaaaggcc ccagatgaat caataaatat aattttatag
2941 taaaaaaaaa aaaaaaaaaa aaaaaa
＜110〉Attached Tongji Hospital, Tongji Univ.
＜120〉pulmonary thromboembolism related gene and application thereof
<160>142
<210>28
<211>2403
<212>DNA
＜213〉human (Homo sapiens)
<400>28
1 tttgcaggtg cctcaggaac cctgaagctg ggctgagcca tgatgctgct gccagaaccc
61 ctgcagaggg cctggtttca ggagactcag agtcctctgt gaaaaagccc ttggagagcg
121 ccccagcagg gctgcacttg gctcctgtga ggaaggggct caggggtctg ggcccctccg
181 cctgggccgg gctgggagcc aggcgggcgg ctgggctgca gcaatggacc gtgagctggc
241 ccagcccgcg tccgtgctga gcctgcctgt cgtctgtggc catgcccatc atgggctcct
301 cggtgtacat cacggtggag ctggccattg ctgtgctggc catcctgggc aatgtgctgg
361 tgtgctgggc cgtgtggctc aagagcaacc tgcagaacgt caccaactac tttgtggtgt
421 cactggcggc ggccgacatc gcagtgggtg tgctcgccat cccctttgcc atcaccatca
481 gcaccgggtt ctgcgctgcc tgccacggct gcctcttcat tgcctgcttc gtcctggtcc
541 tcacgcagag ctccatcttc agtctcctgg ccatcgccat tgaccgctac attgccatcc
601 gcatcccgct ccggtacaat ggcttggtga ccggcacgag ggctaagggc atcattgcca
661 tctgctgggt gctgtcgttt gccatcggcc tgactcccat gctaggttgg aacaactgcg
721 gtcagccaaa ggagggcaag aaccactccc agggctgcgg ggagggccaa gtggcctgtc
781 tctttgagga tgtggtcccc atgaactaca tggtgtactt caacttcttt gcctgtgtgc
841 tggtgcccct gctgctcatg ctgggtgtct atttgcggat cttcctggcg gcgcgacgac
901 agctgaagca gatggagagc cagcctctgc cgggggagcg ggcacggtcc acactgcaga
961 aggaggtcca tgctgccaag tcactggcca tcattgtggg gctctttgcc ctctgctggc
1021 tgcccctaca catcatcaac tgcttcactt tcttctgccc cgactgcagc cacgcccctc
1081 tctggctcat gtacctggcc atcgtcctct cccacaccaa ttcggttgtg aatcccttca
1141 tctacgccta ccgtatccgc gagttccgcc agaccttccg caagatcatt cgcagccacg
1201 tcctgaggca gcaagaacct ttcaaggcag ctggcaccag tgcccgggtc ttggcagctc
1261 atggcagtga cggagagcag gtcagcctcc gtctcaacgg ccacccgcca ggagtgtggg
1321 ccaacggcag tgctccccac cctgagcgga ggcccaatgg ctatgccctg gggctggtga
1381 gtggagggag tgcccaagag tcccagggga acacgggcct cccagacgtg gagctcctta
1441 gccatgagct caagggagtg tgcccagagc cccctggcct agatgacccc ctggcccagg
1501 atggagcagg agtgtcctga tgattcatgg agtttgcccc ttcctaaggg aaggagatct
1561 ttatctttct ggttggcttg accagtcagg ttgggagaag agagagagtg ccaggagacc
1621 ctgagggcag ccggttccta ctttggactg agagaaggga gccccaggct ggagcagcat
1681 gaggcccagc aagaagggct tgggttctga ggaagcagat gtttcatgct gtgaggcctt
1741 gcaccaggtg ggggccacag caccagcagc atctttgctg ggcaggccca gccctccact
1801 gcagaagcat ctggaagcac caccttgtct ccacagagca gcttgggcac agcagactgg
1861 cctggccctg agactgggga gtggctccaa tagcctcctg ccacccacac accactctcc
1921 ctagactctc ctagggttca ggagctgctg ggcccagagg tgacatttga cttttttcca
1981 ggaaaaatgt aagtgtgagg aaaccctttt tattttatta cctttcactc tctggctgct
2041 gggtctgccg tcggtcctgc tgctaacctg gcaccagagc ctctgcccgg ggagcctcag
2101 gcagtcctct cctgctgtca cagctgccat ccacttctca gtcccagggc catctcttgg
2161 agtgacaaag ctgggatcaa ggatagggag ttgtaacaga gcagtgccag agcatgggcc
2221 caggtcccag gggagaggtt ggggctggca ggccactggc atgtgctgag tagcgcagag
2281 ctacccagtg agaggccttg tctaactgcc tttccttcta aagggaatgt ttttttctga
2341 gataaaataa aaacgagcca catcgtgttt taagcttgtc caaatgaaaa aaaaaaaaaa
2401 aaa
＜110〉Attached Tongji Hospital, Tongji Univ.
＜120〉pulmonary thromboembolism related gene and application thereof
<160>142
<210>29
<211>3592
<212>DNA
＜213〉human (Homo sapiens)
<400>29
1 ggcggggggc gcacagagcc agaggggctt gcgagcggcg gctgagggac cgcggggagg
61 gggcgccgag cggctccagc gcagagactc tcactgcacg ccggaggccc cttcctcgct
121 ccgcccgcgc gaccgcgcgc cccagtcccg ccccgccccg ctaaccgccc cagacacagc
181 gctcgccgag ggtcgcttgg accctgatct tacccgtggg caccctgcgc tctgcctgcc
241 gcgaagaccg gctccccgac ccgcagaagt caggagagag ggtgaagcgg agcagcccga
301 ggcggggcag cctcccggag cagcgccgcg cagagcccgg gacaatgggg ccgcggcggc
361 tgctgctggt ggccgcctgc ttcagtctgt gcggcccgct gttgtctgcc cgcacccggg
421 cccgcaggcc agaatcaaaa gcaacaaatg ccaccttaga tccccggtca tttcttctca
481 ggaaccccaa tgataaatat gaaccatttt gggaggatga ggagaaaaat gaaagtgggt
541 taactgaata cagattagtc tccatcaata aaagcagtcc tcttcaaaaa caacttcctg
601 cattcatctc agaagatgcc tccggatatt tgaccagctc ctggctgaca ctctttgtcc
661 catctgtgta caccggagtg tttgtagtca gcctcccact aaacatcatg gccatcgttg
721 tgttcatcct gaaaatgaag gtcaagaagc cggcggtggt gtacatgctg cacctggcca
781 cggcagatgt gctgtttgtg tctgtgctcc cctttaagat cagctattac ttttccggca
841 gtgattggca gtttgggtct gaattgtgtc gcttcgtcac tgcagcattt tactgtaaca
901 tgtacgcctc tatcttgctc atgacagtca taagcattga ccggtttctg gctgtggtgt
961 atcccatgca gtccctctcc tggcgtactc tgggaagggc ttccttcact tgtctggcca
1021 tctgggcttt ggccatcgca ggggtagtgc ctctcgtcct caaggagcaa accatccagg
1081 tgcccgggct caacatcact acctgtcatg atgtgctcaa tgaaaccctg ctcgaaggct
1141 actatgccta ctacttctca gccttctctg ctgtcttctt ttttgtgccg ctgatcattt
1201 ccacggtctg ttatgtgtct atcattcgat gtcttagctc ttccgcagtt gccaaccgca
1261 gcaagaagtc ccgggctttg ttcctgtcag ctgctgtttt ctgcatcttc atcatttgct
1321 tcggacccac aaacgtcctc ctgattgcgc attactcatt cctttctcac acttccacca
1381 cagaggctgc ctactttgcc tacctcctct gtgtctgtgt cagcagcata agctcgtgca
1441 tcgaccccct aatttactat tacgcttcct ctgagtgcca gaggtacgtc tacagtatct
1501 tatgctgcaa agaaagttcc gatcccagca gttataacag cagtgggcag ttgatggcaa
1561 gtaaaatgga tacctgctct agtaacctga ataacagcat atacaaaaag ctgttaactt
1621 aggaaaaggg actgctggga ggttaaaaag aaaagtttat aaaagtgaat aacctgagga
1681 ttctattagt ccccacccaa actttattga ttcacctcct aaaacaacag atgtacgact
1741 tgcatacctg ctttttatgg gagctgtcaa gcatgtattt ttgtcaatta ccagaaagat
1801 aacaggacga gatgacggtg ttattccaag ggaatattgc caatgctaca gtaataaatg
1861 aatgtcactt ctggatatag ctaggtgaca tatacatact tacatgtgtg tatatgtaga
1921 tgtatgcaca cacatatatt atttgcagtg cagtatagaa taggcacttt aaaacactct
1981 ttccccgcac cccagcaatt atgaaaataa tctctgattc cctgatttaa tatgcaaagt
2041 ctaggttggt agagtttagc cctgaacatt tcatggtgtt catcaacagt gagagactcc
2101 atagtttggg cttgtaccac ttttgcaaat aagtgtattt tgaaattgtt tgacggcaag
2161 gtttaagtta ttaagaggta agacttagta ctatctgtgc gtagaagttc tagtgttttc
2221 aattttaaac atatccaagt ttgaattcct aaaattatgg aaacagatga aaagcctctg
2281 ttttgatatg ggtagtattt tttacatttt acacactgta cacataagcc aaaactgagc
2341 ataagtcctc tagtgaatgt aggctggctt tcagagtagg ctattcctga gagctgcatg
2401 tgtccgcccc cgatggagga ctccaggcag cagacacatg ccagggccat gtcagacaca
2461 gattggccag aaaccttcct gctgagcctc acagcagtga gactggggcc actacatttg
2521 ctccatcctc ctgggattgg ctgtgaactg atcatgttta tgagaaactg gcaaagcaga
2581 atgtgatatc ctaggaggta atgaccatga aagacttctc tacccatctt aaaaacaacg
2641 aaagaaggca tggacttctg gatgcccatc cactgggtgt aaacacatct agtagttgtt
2701 ctgaaatgtc agttctgata tggaagcacc cattatgcgc tgtggccact ccaataggtg
2761 ctgagtgtac agagtggaat aagacagaga cctgccctca agagcaaagt agatcatgca
2821 tagagtgtga tgtatgtgta ataaatatgt ttcacacaaa caaggcctgt cagctaaaga
2881 agtttgaaca tttgggttac tatttcttgt ggttataact taatgaaaac aatgcagtac
2941 aggacatata ttttttaaaa taagtctgat ttaattgggc actatttatt tacaaatgtt
3001 ttgctcaata gattgctcaa atcaggtttt cttttaagaa tcaatcatgt cagtctgctt
3061 agaaataaca gaagaaaata gaattgacat tgaaatctag gaaaattatt ctataatttc
3121 catttactta agacttaatg agactttaaa agcatttttt aacctcctaa gtatcaagta
3181 tagaaaatct tcatggaatt cacaaagtaa tttggaaatt aggttgaaac atatctctta
3241 tcttacgaaa aaatggtagc attttaaaca aaatagaaag ttgcaaggca aatgtttatt
3301 taaaagagca ggccaggcgc ggtggctcac gcctgtaatc ccagcacttt gggaggctga
3361 ggcgggtgga tcacgaggtc aggagatcga gaccatcctg gctaacacgg tgaaacccgt
3421 ctctactaaa aatgcaaaaa aaattagccg ggcgtggtgg caggcacctg tagtcccagc
3481 tactcgggag gctgaggcag gagactggcg tgaacccagg aggcggacct tgtagtgagc
3541 cgagatcgcg ccactgtgct ccagcctggg caacagagca agactccatc tc
＜110〉Attached Tongji Hospital, Tongji Univ.
＜120〉pulmonary thromboembolism related gene and application thereof
<160>142
<210>30
<211>2876
<212>DNA
＜213〉human (Homo sapiens)
<400>30
1 tgaaacctaa cccgccctgg ggaggcgcgc agcagaggct ccgattcggg gcaggtgaga
61 ggctgacttt ctctcggtgc gtccagtgga gctctgagtt tcgaatcggc ggcggcggat
121 tccccgcgcg cccggcgtcg gggcttccag gaggatgcgg agccccagcg cggcgtggct
181 gctgggggcc gccatcctgc tagcagcctc tctctcctgc agtggcacca tccaaggaac
241 caatagatcc tctaaaggaa gaagccttat tggtaaggtt gatggcacat cccacgtcac
301 tggaaaagga gttacagttg aaacagtctt ttctgtggat gagttttctg catctgtcct
361 cactggaaaa ctgaccactg tcttccttcc aattgtctac acaattgtgt ttgtggtggg
421 tttgccaagt aacggcatgg ccctgtgggt ctttcttttc cgaactaaga agaagcaccc
481 tgctgtgatt tacatggcca atctggcctt ggctgacctc ctctctgtca tctggttccc
541 cttgaagatt gcctatcaca tacatggcaa caactggatt tatggggaag ctctttgtaa
601 tgtgcttatt ggctttttct atggcaacat gtactgttcc attctcttca tgacctgcct
661 cagtgtgcag aggtattggg tcatcgtgaa gcccatgggg cactccagga agaaggcaaa
721 cattgccatt ggcatctccc tggcaatatg gctgctgatt ctgctggtca ccatcccttt
781 gtatgtcgtg aagcagacca tcttcattcc tgccctgaac atcacgacct gtcatgatgt
841 tttgcctgag cagctcttgg tgggagacat gttcaattac ttcctctctc tggccattgg
901 ggtctttctg ttcccagcct tcctcacagc ctctgcctat gtgctgatga tcagaatgct
961 gcgatcttct gccatggatg aaaactcaga gaagaaaagg aagagggcca tcaaactcat
1021 tgtcactgtc ctggccatgt acctgatctg cttcactcct agtaaccttc tgcttgtggt
1081 gcattatttt ctgattaaga gccagggcca gagccatgtc tatgccctgt acattgtagc
1141 cctctgcctc tctaccctta acagctgcat cgaccccttt gtctattact ttgtttcaca
1201 tgatttcagg gatcatgcaa agaacgctct cctttgccga agtgtccgca ctgtaaagca
1261 gatgcaagta tccctcacct caaagaaaca ctccaggaaa tccagctctt actcttcaag
1321 ttcaaccact gttaagacct cctattgagt tttccaggtc ctcagatggg aattgcacag
1381 taggatgtgg aacctgttta atgttatgag gacgtgtctg ttatttccta atcaaaaagg
1441 tctcaccaca taccatgtgg atgcagcacc tctcaggatt gctaggagct cccctgtttg
1501 catgagaaaa gtagtccccc aaattaacat cagtgtctgt ttcagaatct ctctactcag
1561 atgaccccag aaactgaacc aacagaagca gacttttcag aagatggtga agacagaaac
1621 ccagtaactt gcaaaaagta gacttggtgt gaagactcac ttctcagctg aaattatata
1681 tatacacata tatatatttt acatctggga tcatgataga cttgttaggg cttcaaggcc
1741 ctcagagatg atcagtccaa ctgaacgacc ttacaaatga ggaaaccaag ataaatgagc
1801 tgccagaatc aggtttccaa tcaacagcag tgagttggga ttggacagta gaatttcaat
1861 gtccagtgag tgaggttctt gtaccacttc atcaaaatca tggatcttgg ctgggtgcgg
1921 tgcctcatgc ctgtaatcct agcactttgg gaggctgagg caggcaatca cttgaggtca
1981 ggagttcgag accagcctgg ccatcatggc gaaacctcat ctctactaaa aatacaaaag
2041 ttaaccaggt gtgtggtgca cgtttgtaat cccagttact caggaggctg aggcacaaga
2101 attgagtatc actttaactc aggaggcaga ggttgcagtg agccgagatt gcaccactgc
2161 actccagctt gggtgataaa ataaaataaa atagtcgtga atcttgttca aaatgcagat
2221 tcctcagatt caataatgag agctcagact gggaacaggg cccaggaatc tgtgtggtac
2281 aaacctgcat ggtgtttatg cacacagaga tttgagaacc attgttctga atgctgcttc
2341 catttgacaa agtgccgtga taatttttga aaagagaagc aaacaatggt gtctctttta
2401 tgttcagctt ataatgaaat ctgtttgttg acttattagg actttgaatt atttctttat
2461 taaccctctg agtttttgta tgtattatta ttaaagaaaa atgcaatcag gattttaaac
2521 atgtaaatac aaattttgta taacttttga tgacttcagt gaaattttca ggtagtctga
2581 gtaatagatt gttttgccac ttagaatagc atttgccact tagtatttta aaaaataatt
2641 gttggagtat ttattgtcag ttttgttcac ttgttatcta atacaaaatt ataaagcctt
2701 cagagggttt ggaccacatc tctttggaaa atagtttgca acatatttaa gagatacttg
2761 atgccaaaat gactttatac aacgattgta tttgtgactt ttaaaaataa ttattttatt
2821 gtgtaattga tttataaata acaaaatttt ttttacaact taaaaaaaaa aaaaaa
＜110〉Attached Tongji Hospital, Tongji Univ.
＜120〉pulmonary thromboembolism related gene and application thereof
<160>142
<210>31
<211>1629
<212>DNA
＜213〉human (Homo sapiens)
<400>31
1 acacatcagg ggcttgctct tgcaaaacca aaccacaaga cagacttgca aaagaaggca
61 tgcacagctc agcactgctc tgttgcctgg tcctcctgac tggggtgagg gccagcccag
121 gccagggcac ccagtctgag aacagctgca cccacttccc aggcaacctg cctaacatgc
181 ttcgagatct ccgagatgcc ttcagcagag tgaagacttt ctttcaaatg aaggatcagc
241 tggacaactt gttgttaaag gagtccttgc tggaggactt taagggttac ctgggttgcc
301 aagccttgtc tgagatgatc cagttttacc tggaggaggt gatgccccaa gctgagaacc
361 aagacccaga catcaaggcg catgtgaact ccctggggga gaacctgaag accctcaggc
421 tgaggctacg gcgctgtcat cgatttcttc cctgtgaaaa caagagcaag gccgtggagc
481 aggtgaagaa tgcctttaat aagctccaag agaaaggcat ctacaaagcc atgagtgagt
541 ttgacatctt catcaactac atagaagcct acatgacaat gaagatacga aactgagaca
601 tcagggtggc gactctatag actctaggac ataaattaga ggtctccaaa atcggatctg
661 gggctctggg atagctgacc cagccccttg agaaacctta ttgtacctct cttatagaat
721 atttattacc tctgatacct caacccccat ttctatttat ttactgagct tctctgtgaa
781 cgatttagaa agaagcccaa tattataatt tttttcaata tttattattt tcacctgttt
841 ttaagctgtt tccatagggt gacacactat ggtatttgag tgttttaaga taaattataa
901 gttacataag ggaggaaaaa aaatgttctt tggggagcca acagaagctt ccattccaag
961 cctgaccacg ctttctagct gttgagctgt tttccctgac ctccctctaa tttatcttgt
1021 ctctgggctt ggggcttcct aactgctaca aatactctta ggaagagaaa ccagggagcc
1081 cctttgatga ttaattcacc ttccagtgtc tcggagggat tcccctaacc tcattcccca
1141 accacttcat tcttgaaagc tgtggccagc ttgttattta taacaaccta aatttggttc
1201 taggccgggc gcggtggctc acgcctgtaa tcccagcact ttgggaggct gaggcgggtg
1261 gatcacttga ggtcaggagt tcctaaccag cctggtcaac atggtgaaac cccgtctcta
1321 ctaaaaatac aaaaattagc cgggcatggt ggcgcgcacc tgtaatccca gctacttggg
1381 aggctgaggc aagagaattg cttgaaccca ggagatggaa gttgcagtga gctgatatca
1441 tgcccctgta ctccagcctg ggtgacagag caagactctg tctcaaaaaa taaaaataaa
1501 aataaatttg gttctaatag aactcagttt taactagaat ttattcaatt cctctgggaa
1561 tgttacattg tttgtctgtc ttcatagcag attttaattt tgaataaata aatgtatctt
1621 attcacatc
＜110〉Attached Tongji Hospital, Tongji Univ.
＜120〉pulmonary thromboembolism related gene and application thereof
<160>142
<210>32
<211>1185
<212>DNA
＜213〉human (Homo sapiens)
<400>32
1 gctcagggca catgcctccc ctccccaggc cgcggcccag ctgaccctcg gggctccccc
61 ggcagcggac agggaagggt taaaggcccc cggctccctg ccccctgccc tggggaaccc
121 ctggccctgt ggggacatga actgtgtttg ccgcctggtc ctggtcgtgc tgagcctgtg
181 gccagataca gctgtcgccc ctgggccacc acctggcccc cctcgagttt ccccagaccc
241 tcgggccgag ctggacagca ccgtgctcct gacccgctct ctcctggcgg acacgcggca
301 gctggctgca cagctgaggg acaaattccc agctgacggg gaccacaacc tggattccct
361 gcccaccctg gccatgagtg cgggggcact gggagctcta cagctcccag gtgtgctgac
421 aaggctgcga gcggacctac tgtcctacct gcggcacgtg cagtggctgc gccgggcagg
481 tggctcttcc ctgaagaccc tggagcccga gctgggcacc ctgcaggccc gactggaccg
541 gctgctgcgc cggctgcagc tcctgatgtc ccgcctggcc ctgccccagc cacccccgga
601 cccgccggcg cccccgctgg cgcccccctc ctcagcctgg gggggcatca gggccgccca
661 cgccatcctg ggggggctgc acctgacact tgactgggcc gtgaggggac tgctgctgct
721 gaagactcgg ctgtgacccg gggcccaaag ccaccaccgt ccttccaaag ccagatctta
781 tttatttatt tatttcagta ctgggggcga aacagccagg tgatcccccc gccattatct
841 ccccctagtt agagacagtc cttccgtgag gcctggggga catctgtgcc ttatttatac
901 ttatttattt caggagcagg ggtgggaggc aggtggactc ctgggtcccc gaggaggagg
961 ggactggggt cccggattct tgggtctcca agaagtctgt ccacagactt ctgccctggc
1021 tcttccccat ctaggcctgg gcaggaacat atattattta tttaagcaat tacttttcat
1081 gttggggtgg ggacggaggg gaaagggaag cctgggtttt tgtacaaaaa tgtgagaaac
1141 ctttgtgaga cagagaacag ggaattaaat gtgtcataca tatcc
＜110〉Attached Tongji Hospital, Tongji Univ.
＜120〉pulmonary thromboembolism related gene and application thereof
<160>142
<210>33
<211>3122
<212>DNA
＜213〉human (Homo sapiens)
<400>33
1 tcggcggaga cctgctcccc agaagacgcc tcctgcttcc cactgcgccc tggaggacgc
61 gggctggctg ctgggcgagc tcggcggagg cacgcccctc gcctccccgc ggagtgcgga
121 ctcgccccgg tgcccaaact ccgcccaccc tctagggagc tccgctctcc cgcctaaccc
181 cggcactccg gacagagctg ggcctgggga aggggttcct gaactacgcg gacgccgaac
241 gggacgcgct gcagaagcgc acgagtctgc ggccacgcgc gctccgatgg ctgccaggag
301 ctgagctcag ggtgggcgga ggaagcggtt agacgccccg aaactgagct gcacgtttct
361 aaggtaggga ggaggaagat gcccccaatt aagttgatct ttgagccaag gaggctgggg
421 agcagcctcc ccaagctaga gccctgcaga gcgagtttcc cttgacctcg ctgcgcctct
481 ggcgcgctct gcagcgcgga cccgcggccc ctcgggaaag cgcagtcgga aagttatccg
541 cggcggttcc ctgcgcgccc tgttgtgtaa gctcggcgtt gccagcggac ggagaagttg
601 ctggcttgcc cgatagccca gttcggtggc ggcccggggc ggatttcatg gcccgcggcg
661 aacgcggggc cagagctggc gtgggcgagc ccctgcgcgc cccctcccgc ggggatccag
721 ttcgcctgct cccttccgct cgctggcttt tccgatgctt gctgcgcccc tggccgccgc
781 tgccctctcg ccgcctccta cccctcggag ccgccgccta agtcgaggag gagagaatga
841 ccgaggtgct gtggccggct gtccccaacg ggacggacgc tgccttcctg gccggtccgg
901 gttcgtcctg ggggaacagc acggtcgcct ccactgccgc cgtctcctcg tcgttcaaat
961 gcgccttgac caagacgggc ttccagtttt actacctgcc ggctgtctac atcttggtat
1021 tcatcatcgg cttcctgggc aacagcgtgg ccatctggat gttcgtcttc cacatgaagc
1081 cctggagcgg catctccgtg tacatgttca atttggctct ggccgacttc ttgtacgtgc
1141 tgactctgcc agccctgatc ttctactact tcaataaaac agactggatc ttcggggatg
1201 ccatgtgtaa actgcagagg ttcatctttc atgtgaacct ctatggcagc atcttgtttc
1261 tgacatgcat cagtgcccac cggtacagcg gtgtggtgta ccccctcaag tccctgggcc
1321 ggctcaaaaa gaagaatgcg atctgtatca gcgtgctggt gtggctcatt gtggtggtgg
1381 cgatctcccc catcctcttc tactcaggta ccggggtccg caaaaacaaa accatcacct
1441 gttacgacac cacctcagac gagtacctgc gaagttattt catctacagc atgtgcacga
1501 ccgtggccat gttctgtgtc cccttggtgc tgattctggg ctgttacgga ttaattgtga
1561 gagctttgat ttacaaagat ctggacaact ctcctctgag gagaaaatcg atttacctgg
1621 taatcattgt actgactg tttttgctg tgtcttacatccc tttccatgtg atgaaaacga
1681 tgaacttgag ggcccggctt gattttcaga ccccagcaat gtgtgctttc aatgacaggg
1741 tttatgccac gtatcaggtg acaagaggtc tagcaagtct caacagttgt gtggacccca
1801 ttctctattt cttggcggga gatactttca gaaggagact ctcccgagcc acaaggaaag
1861 cttctagaag aagtgaggca aatttgcaat ccaagagtga agacatgacc ctcaatattt
1921 tacctgagtt caagcagaat ggagatacaa gcctgtgaag gcacaagaat ctccaaacac
1981 ctctctgttg taatatggta ggatgcttaa cagaatcaag tacttttccc ctctttaact
2041 ttctagttta gaaaaaaatc aaaccaagaa aatagtgagt taaaaaaata atagaagtag
2101 aaatgcccac atccacactt agcttgtttg ggtttgcttt cacagtctct cttccttctg
2161 actagaagta tgtataataa aacaatacta cctagttaaa catttacttt ctcttttgcc
2221 tttaaaatgt gcaggctttt ctgtttaaag tgtgtgtgca catgagtact ggggctgttt
2281 ttgatattag taatttctct aagaaaacta gccccctgca acttgagttt gtggtttatc
2341 tagcctttat tgttttttta aaatccacag taggaataaa aaatctatat tctcagaaat
2401 atctagcatg gtatataaca aaacactaaa ctcatcagtt catccggcat cagatcaatg
2461 gatctctgag cggggtgttt ttttcagtgt cttataagca tagatgatag ttgactgagt
2521 ttctttaggg cattgaatag acaagtaaag ctaatgaatt taaaagcctg aaaagtgatt
2581 gttttccagt tatttctgga aaaggtctca ttatatattg ggtgctaaat gtttgatggg
2641 gaaagcctgc atatattatc gtactggtaa aatgcattca aaataattaa agtgcatgta
2701 ttttccttgt aaacaccatg agctctctta gacatcttgt gataaagagc atttacttgc
2761 cccactgctg tgcaatgcct taggactttg tttgtgttcc aggacaagtg ttcactcaca
2821 tctgtaaaaa caattttaag aattgcaaat aaattacaga ccaaagattg agtaaagtca
2881 aataactgtt agtaagttga aggatattgg acaggaggac agtatttcag aaaaggagag
2941 gttgacagtc atccacaagg catagcctcc aagtatactc tcaaatgtat gaagcaactg
3001 gggtgggcag aagacatttt agaatgaggg ctttagttta aattaaagtc atggtggaga
3061 agactcttgc ttcctccaag tgtttgaaaa cacaaaatgc gatatgaaaa aaaaaaaaaa
3121 aa
＜110〉Attached Tongji Hospital, Tongji Univ.
＜120〉pulmonary thromboembolism related gene and application thereof
<160>142
<210>34
<211>2395
<212>DNA
＜213〉human (Homo sapiens)
<400>34
1 gccgccgtcg gcgcgctggg tgcgggaagg gggctctgga tttcggtccc tccccttttt
61 cctctgagtc tcggaacgct ccagctctca gaccctcttc ctcccaggta aaggccggga
121 gaggagggcg catctctttt ccaggcaccc caccatgggc aatgcctcca atgactccca
181 gtctgaggac tgcgagacgc gacagtggct tcccccaggc gaaagcccag ccatcagctc
241 cgtcatgttc tcggccgggg tgctggggaa cctcatagca ctggcgctgc tggcgcgccg
301 ctggcggggg gacgtggggt gcagcgccgg ccgcaggagc tccctctcct tgttccacgt
361 gctggtgacc gagctggtgt tcaccgacct gctcgggacc tgcctcatca gcccagtggt
421 actggcttcg tacgcgcgga accagaccct ggtggcactg gcgcccgaga gccgcgcgtg
481 cacctacttc gctttcgcca tgaccttctt cagcctggcc acgatgctca tgctcttcgc
541 catggccctg gagcgctacc tctcgatcgg gcacccctac ttctaccagc gccgcgtctc
601 gcgctccggg ggcctggccg tgctgcctgt catctatgca gtctccctgc tcttctgctc
661 gctgccgctg ctggactatg ggcagtacgt ccagtactgc cccgggacct ggtgcttcat
721 ccggcacggg cggaccgctt acctgcagct gtacgccacc ctgctgctgc ttctcattgt
781 ctcggtgctc gcctgcaact tcagtgtcat tctcaacctc atccgcatgc accgccgaag
841 ccggagaagc cgctgcggac cttccctggg cagtggccgg ggcggccccg gggcccgcag
901 gagaggggaa agggtgtcca tggcggagga gacggaccac ctcattctcc tggctatcat
961 gaccatcacc ttcgccgtct gctccttgcc tttcacgatt tttgcatata tgaatgaaac
1021 ctcttcccga aaggaaaaat gggacctcca agctcttagg tttttatcaa ttaattcaat
1081 aattgaccct tgggtctttg ccatccttag gcctcctgtt ctgagactaa tgcgttcagt
1141 cctctgttgt cggatttcat taagaacaca agatgcaaca caaacttcct gttctacaca
1201 gtcagatgcc agtaaacagg ctgacctttg aggtcagtag tttaaaagtt cttagttata
1261 tagcatctgg aagatcattt tgaaattgtt ccttggagaa atgaaaacag tgtgtaaaca
1321 aaatgaagct gccctaataa aaaggagtat acaaacattt aagctgtggt caaggctaca
1381 gatgtgctga caaggcactt catgtaaagt gtcagaagga gctacaaaac ctaccctcag
1441 tgagcatggt acttggcctt tggaggaaca atcggctgca ttgaagatcc agctgcctat
1501 tgatttaagc tttcctgttg aatgacaaag tatgtggttt tgtaatttgt ttgaaacccc
1561 aaacagtgac tgtactttct attttaatct tgctactacc gttatacaca tatagtgtac
1621 agccagacta gattaaactt catatgtaat ctctaggaag tcaatatgtg gaagcaacca
1681 agcctgctgt cttgtgatca cttagcgaac cctttatttg aacaatgaag ttgaaaatca
1741 taggcacctt ttactgtgat gtttgtgtat gtgggagtac tctcatcact acagtattac
1801 tcttacaaga gtggactcag tgggttaaca tcagttttgt ttactcatcc tccaggaact
1861 gcaggtcaag ttgtcaggtt atttatttta taatgtccat atgctaatag tgatcaagaa
1921 gactttagga atggttctct caacaagaaa taatagaaat gtctcaaggc agttaattct
1981 cattaatact cttattatcc tatttctggg ggaggatgta cgtggccatg tatgaagcca
2041 aatattaggc ttaaaaactg aaaaatctgg ttcattcttc agatatactg gaaccctttt
2101 aaagttgata ttggggccat gagtaaaata gattttataa gatgactgtg ttgtaccaaa
2161 attcatctgt ctatatttta tttagggaac atggtttgac tcatcttata tgggaaacca
2221 tgtagcagtg agtcatatct taatatattt ctaaatgttt ggcatgtaaa tgtaaactca
2281 gcatcaaaat atttcagtga atttgcactg tttaatcata gttactgtgt aaactcatct
2341 gaaatgttac aaaaataaac tataaaacaa aaatttgaaa aaaaaaaaaa aaaaa
＜110〉Attached Tongji Hospital, Tongji Univ.
＜120〉pulmonary thromboembolism related gene and application thereof
<160>142
<210>35
<211>3466
<212>DNA
＜213〉human (Homo sapiens)
<400>35
1 gccccgcagt ttccgcgcta agggaacgag tgcgcggagg ggacgagcgg ctggaccaca
61 gccggcgccc gatcaggatc tccgcgctgg gatcggtgga acttgaggca gcggcggcgc
121 ggggcgccat ggcacaccga gcggctccgt cttctgctcc tcagagagcc cggctggcgg
181 cctgggatga caagatgtct ggactgcaat cctgcacagt tttgagaggg agatgacttg
241 agtggttggc ttttatctcc acaacaatgt ccatgaacaa ttccaaacag ctagtgtctc
301 ctgcagctgc gcttctttca aacacaacct gccagacgga aaaccggctt tccgtatttt
361 tttcagtaat cttcatgaca gtgggaatct tgtcaaacag ccttgccatc gccattctca
421 tgaaggcata tcagagattt agacagaagt ccaaggcatc gtttctgctt ttggccagtg
481 gcctggtaat cactgatttc tttggccatc tcatcaatgg agccatagca gtatttgtat
541 atgcttctga taaagaatgg atccgctttg accaatcaaa tgtcctttgc agtatttttg
601 gtatctgcat ggtgttttct ggtctgtgcc cacttcttct aggcagtgtg atggccattg
661 agcggtgtat tggagtcaca aaaccaatat ttcattctac gaaaattaca tccaaacatg
721 tgaaaatgat gttaagtggt gtgtgcttgt ttgctgtttt catagctttg ctgcccatcc
781 ttggacatcg agactataaa attcaggcgt cgaggacctg gtgtttctac aacacagaag
841 acatcaaaga ctgggaagat agattttatc ttctactttt ttcttttctg gggctcttag
901 cccttggtgt ttcattgttg tgcaatgcaa tcacaggaat tacactttta agagttaaat
961 ttaaaagtca gcagcacaga caaggcagat ctcatcattt ggaaatggta atccagctcc
1021 tggcgataat gtgtgtctcc tgtatttgtt ggagcccatt tctggttaca atggccaaca
1081 ttggaataaa tggaaatcat tctctggaaa cctgtgaaac aacacttttt gctctccgaa
1141 tggcaacatg gaatcaaatc ttagatcctt gggtatatat tcttctacga aaggctgtcc
1201 ttaagaatct ctataagctt gccagtcaat gctgtggagt gcatgtcatc agcttacata
1261 tttgggagct tagttccatt aaaaattcct taaaggttgc tgctatttct gagtcaccag
1321 ttgcagagaa atcagcaagc acctagctta ataggacagt aaatctgtgt ggggctagaa
1381 caaaattaag acatgtttgg caatatttca gttagttaaa tacctgtagc ctaactggaa
1441 aattcaggct tcatcatgta gtttgaagat actattgtca gattcaggtt ttgaaatttg
1501 tcaaataaac aggataactg tacatttttc acttgttttt gccaatggga ggtagacaca
1561 ataaaataat gccatgggag tcacactgaa agcaattttg agcttatctg tcttatttat
1621 gctttgagtg aatcatctgt tgaggtctaa tgcctttact tggcctattt gccagagaac
1681 atcttaatgc agcctgcata gtgaaatggt tattttgaga tcaccgctct gtagctaacc
1741 cttataaact aggctcagta aaataaagca ctcttatttt ttgatctggc ctattttgcc
1801 cctcattgtg tagcctcaat taacacatgc atggtcatga cacccagaat tcatgatggt
1861 ttgttataac aacctctgca tattccaggt ctggcagaca ggttgcctga ccctgcaatc
1921 ctatctagaa tgggcccatt cttgtcatat ttgacaaata ggactgccta catttattat
1981 tatgaaggtc gattgttgtt ggaagtgttt tttcatgtca tagattagca attttcaaat
2041 aattattttt tctctgaaaa ttttgtgtgt gattgcacaa taaataattt ttagagaaac
2101 aaaggctctt tctcagcaca ttgatgggca actagaatta cagcagtttc aaaactctac
2161 catggataat gcaaacaaac cgaagctaca tgccaatgat aggtgcaaag aatattggca
2221 aaaggtgctt taccttgagc cattatttgt gtcagagaac aaaagaaaca gaatcaatat
2281 ataaaattca aagactatct gcagctagtg tgtttcttct ttacacacat atacacacag
2341 acatcagaaa attctgttga gagcaggttc attaaatttg taagatggca tattctaaag
2401 cctgtgctac cagtactaag aggggaagac tggcaatttg ccaagcactt ggggattatt
2461 ataacaatta actaggagat caagagataa taatctctcc ccaaattttc caataataat
2521 tgagactttt tctttgcttg tttgtgtaat tcaaccaaaa gaatttcaat acccattcaa
2581 attgtcctag gtctatcaga aattagggaa ggtagtcctg ctttataata ggaaaatgta
2641 tttctgtata agagttcttt gctttcatta acttggattc atttaaaaat taatcttccc
2701 tgttaggctg atttcagatt ctctaggaaa tctgtgtaag taaccagaag acctttcaga
2761 tggtttattt gctttcagca gagaatttat ttcatacagt tacttaagag tgttgatgtc
2821 ttgtgaacag agatataagg aaccattctc catccttcct tatcatgctg ggtacaatgc
2881 ttctatgaat atttccatgt attttgactg gggagaggca tggagaagaa actctcattc
2941 aggggctcca ggatccttct ccttgaggct tctaaataaa tggcagaatt cttgctgtat
3001 tgccatgatg tcaccctggc catgtgtact gacttgagga gatcttgcaa catggccatg
3061 tgcaaggctt taaggagtga gagagatgtg tacatatctt aggagggtta tctatgttat
3121 ctgagtatat gtttgggtaa ccaaattggt cttaaaaatg atgttaaccc aagaagtaga
3181 catcaaaaat taaaaaaaaa aaaaggaatg tgttttcatt gttttaagtt tttcttctga
3241 gtaaaacaaa attatagaaa acaaatgcaa caatgtgcac atctgactta agagtttcat
3301 ttctgttatt atatgtgttg catgtagctt ggcgatttac tgtgtaatga ataatagact
3361 ggaacatcta ccaataactt tcacataaat gttcaaaata gaagtgtatt ttttcaggtt
3421 tctggaaata aatagtaaaa taaatggcaa aaaaaaaaaa aaaaaa
＜110〉Attached Tongji Hospital, Tongji Univ.
＜120〉pulmonary thromboembolism related gene and application thereof
<160>142
<210>36
<211>839
<212>DNA
＜213〉human (Homo sapiens)
<400>36
1 ccatttcaac tttaacacag catgatcgaa acatacaacc aaacttctcc ccgatctgcg
61 gccactggac tgcccatcag catgaaaatt tttatgtatt tacttactgt ttttcttatc
121 acccagatga ttgggtcagc actttttgct gtgtatcttc atagaaggtt ggacaagata
181 gaagatgaaa ggaatcttca tgaagatttt gtattcatga aaacgataca gagatgcaac
241 acaggagaaa gatccttatc cttactgaac tgtgaggaga ttaaaagcca gtttgaaggc
301 tttgtgaagg atataatgtt aaacaaagag gagacgaaga aagaaaacag ctttgaaatg
361 caaaaaggtg atcagaatcc tcaaattgcg gcacatgtca taagtgaggc cagcagtaaa
421 acaacatctg tgttacagtg ggctgaaaaa ggatactaca ccatgagcaa caacttggta
481 accctggaaa atgggaaaca gctgaccgtt aaaagacaag gactctatta tatctatgcc
541 caagtcacct tctgttccaa tcgggaagct tcgagtcaag ctccatttat agccagcctc
601 tgcctaaagt cccccggtag attcgagaga atcttactca gagctgcaaa tacccacagt
661 tccgccaaac cttgcaggca acaatccatt cacttgggag gagtatttga attgtaacca
721 ggtgcttcgg tgtttgtcaa tgtgactgat ccaagccaag tgagccatgg cactggctca
781 cgtcctttgg cttactcaaa ctctgaacag tgtcaccttg caggctgtgg tggagctga
＜110〉Attached Tongji Hospital, Tongji Univ.
＜120〉pulmonary thromboembolism related gene and application thereof
<160>142
<210>37
<211>1536
<212>DNA
＜213〉human (Homo sapiens)
<400>37
1 gattacggca agcttggcac gagggcaggc attgcccgag gccagccgag ccgccagagc
61 cgcgggccgc gggggtgtcg cgggcccaac cccaggatgc tcccctgcac ctcctgccta
121 cccgggtctc tactgctctg ggcgctgcta ctgttgctct tgggatcagc ttctcctcag
181 gattctgaag agcccgacag ctacacggaa tgcacagatg gctatgagtg ggacccagac
241 agccagcact gccgggatgt caacgagtgt ctgaccatcc ctgaggcctg caagggggaa
301 atgaagtgca tcaaccacta cgggggctac ttgtgcctgc cccgctccgc tgccgtcatc
361 aacgacctac acggcgaggg acccccgcca ccagtgcctc ccgctcaaca ccccaacccc
421 tgcccaccag gctatgagcc cgacgatcag gacagctgtg tggatgtgga cgagtgtgcc
481 caggccctgc acgactgtcg ccccagccag gactgccata acttgcctgg ctcctatcag
541 tgcacctgcc ctgatggtta ccgcaagatc gggcccgagt gtgtggacat agacgagtgc
601 cgctaccgct actgccagca ccgctgcgtg aacctgcctg gctccttccg ctgccagtgc
661 gagccgggtt tccagctggg gcctaacaac cgctcctgtg ttgatgtgaa cgagtgtgac
721 atgggggccc catgcgagca gcgctgcttc aactcctatg ggaccttcct gtgtcgctgc
781 caccagggct atgagctgca tcgggatggc ttctcctgca gtgatattga tgagtgtagc
841 tactccagct acctctgtca gtaccgctgc gtcaacgagc caggccgttt ctcctgccac
901 tgcccacagg gttaccagct gctggccaca cgcctctgcc aagacattga tgagtgtgag
961 tctggtgcgc accagtgctc cgaggcccaa acctgtgtca acttccatgg gggctaccgc
1021 tgcgtggaca ccaaccgctg cgtggagccc tacatccagg tctctgagaa ccgctgtctc
1081 tgcccggcct ccaaccctct atgtcgagag cagccttcat ccattgtgca ccgctacatg
1141 accatcacct cggagcggag cgtgcccgct gacgtgttcc agatccaggc gacctccgtc
1201 taccccggtg cctacaatgc ctttcagatc cgtgctggaa actcgcaggg ggacttttac
1261 attaggcaaa tcaacaacgt cagcgccatg ctggtcctcg cccggccggt gacgggcccc
1321 cgggagtacg tgctggacct ggagatggtc accatgaatt ccctcatgag ctaccgggcc
1381 agctctgtac tgaggctcac cgtctttgta ggggcctaca ccttctgagg agcaggaggg
1441 agccaccctc cctgcagcta ccctagctga ggagcctgtt gtgaggggca gaatgagaaa
1501 ggcaataaag ggagaaagaa aaaaaaaaaa aaaaaa
＜110〉Attached Tongji Hospital, Tongji Univ.
＜120〉pulmonary thromboembolism related gene and application thereof
<160>142
<210>38
<211>1101
<212>DNA
＜213〉human (Homo sapiens)
<400>38
1 atttgaggaa ccatgtctcc atccccgacc gccctcttct gtcttgggct gtgtctgggg
61 cgtgtgccag cgcagagtgg accgctcccc aagccctccc tccaggctct gcccagctcc
121 ctggtgcccc tggagaagcc agtgaccctc cggtgccagg gacctccggg cgtggacctg
181 taccgcctgg agaagctgag ttccagcagg taccaggatc aggcagtcct cttcatcccg
241 gccatgaaga gaagtctggc tggacgctac cgctgctcct accagaacgg aagcctctgg
301 tccctgccca gcgaccagct ggagctcgtt gccacgggag tttttgccaa accctcgctc
361 tcagcccagc ccggcccggc ggtgtcgtca ggaggggacg taaccctaca gtgtcagact
421 cggtatggct ttgaccaatt tgctctgtac aaggaagggg accctgcgcc ctacaagaat
481 cccgagagat ggtaccgggc tagtttcccc atcatcacgg tgaccgccgc ccacagcgga
541 acctaccgat gctacagctt ctccagcagg gacccatacc tgtggtcggc ccccagcgac
601 cccctggagc ttgtggtcac aggaacctct gtgaccccca gccggttacc aacagaacca
661 ccttcctcgg tagcagaatt ctcagaagcc accgctgaac tgaccgtctc attcacaaac
721 aaagtcttca caactgagac ttctaggagt atcaccacca gtccaaagga gtcagactct
781 ccagctggtc ctgcccgcca gtactacacc aagggcaacc tggtccggat atgcctcggg
841 gctgtgatcc taataatcct ggcggggttt ctggcagagg actggcacag ccggaggaag
901 cgcctgcggc acaggggcag ggctgtgcag aggccgcttc cgcccctgcc gcccctcccg
961 cagacccgga aatcacacgg gggtcaggat ggaggccgac aggatgttca cagccgcggg
1021 ttatgttcat gaccgctgaa ccccaggcac ggtcgtatcc aagggaggga tcatggcatg
1081 ggaggcgact caatcactag t
＜110〉Attached Tongji Hospital, Tongji Univ.
＜120〉pulmonary thromboembolism related gene and application thereof
<160>142
<210>39
<211>1534
<212>DNA
＜213〉human (Homo sapiens)
<400>39
1 tcatgtgggg gcgactgctc ctgtggcccc tggtgctggg gttcagcctg tctggcggca
61 cccagacccc cagcgtctac gacgagagcg ggagcaccgg aggtggtgat gacagcacgc
121 cctcaatcct gcctgccccc cgcggctacc caggccaagt ctgtgccaat gacagtgaca
181 ccctggagct cccggacagc tcacgggcac tgcttctggg ctgggtgccc accaggctgg
241 tgcccgccct ctatgggctg gtcctggtgg tggggctgcc ggccaatggg ctggcgctgt
301 gggtgctggc cacgcaggca cctcggctgc cctccaccat gctgctgatg aacctcgcga
361 ctgctgacct cctgctggcc ctggcgctgc ccccgcggat cgcctaccac ctgcgtggcc
421 agcgctggcc cttcggggag gccgcctgcc gcctggccac ggccgcactc tatggtcaca
481 tgtatggctc agtgctgctg ctggccgccg tcagcctgga tcgctacctg gccctggtgc
541 acccgctgcg ggcccgcgcc ctgcgtggcc ggcgcctggc ccttggactc tgcatggctg
601 cttggctcat ggcggccgcc ctggcactgc ccctgacact gcagcggcag accttccggc
661 tggcgcgctc cgatcgcgtg ctctgccatg acgcgctgcc cctggacgca caggcctccc
721 actggcaacc ggccttcacc tgcctggcgc tgttgggctg tttcctgccc ctgctggcca
781 tgctgctgtg ctacggggcc accctgcaca cgctggcggc cagcggccgg cgctacggcc
841 acgcgctgag gctgaccgca gtggtgctgg cctccgccgt ggccttcttc gtgcccagca
901 acctgctgct gctgctgcat tactcggacc cgagccccag cgcctggggc aacctctatg
961 gtgcctacgt gcccagcctg gcgctgagca ccctcaacag ctgcgtggat cccttcatct
1021 actactacgt gtcggccgag ttcagggaca aggtgcgggc agggctcttc caacggtcgc
1081 cgggggacac cgtggcctcc aaggcctctg cggaaggggg cagccggggc atgggcaccc
1141 actcctcttt gctccagtga cacaaagtgg ggaaggctgt actgggtcga acagggtccc
1201 ttcccccact tcacgtcctt cctgggacct cagaatgtga ccttatttgg aaatagggtt
1261 gttacaactg tcactagcag aggtcacttt ggagaagggt gggccttaca tccagtgtgg
1321 gtggtgtcct cataagataa ggagaggcca ggcctggtgg ctcacgcctg taatcccagc
1381 actttaagag gccaaggcgg atggatcact tgagcccagg agttcaacac cagcctgagc
1441 aacatggtaa aaccccatct ctaccaaaaa tacaaaaatt agctgggctt ggtggctggc
1501 gcctgtaatc ccagctactc angagactga ggca
＜110〉Attached Tongji Hospital, Tongji Univ.
＜120〉pulmonary thromboembolism related gene and application thereof
<160>142
<210>40
<211>504
<212>DNA
＜213〉human (Homo sapiens)
<400>40
1 ttcctgcaca gagagattca cgcaccctca agagtgtggg tgagacatat acagcctgtt
61 agacctgaag gcagatggct cttcttaagg ccaataagga tctcatttcc gcaggattga
121 aggagttcag cgttctgctg aatcagcagg tcttcaatga tcctctcgtc tctgaagaag
181 acatggtgac tgtggtggag gactggatga acttctacat caactattac aggcagcagg
241 tgacagggga gccccaagag cgagacaagg ctctgcagga gcttcggcaa gagctgaaca
301 ctctggccaa ccctttcctg gccaagtaca gggacttcct gaagtctcat gagctcccga
361 gtcacccacc gccctcctcc tagctcaggg acccagcccc tcctctctga gaaactctga
421 ccttcatgtc cttaggctgt gctcctgcca ctctaccctg acacctcaat aaagaccagt
481 gctggttttg ttggaaaaaa aaaa
＜110〉Attached Tongji Hospital, Tongji Univ.
＜120〉pulmonary thromboembolism related gene and application thereof
<160>142
<210>41
<211>1312
<212>DNA
＜213〉human (Homo sapiens)
<400>41
1 gcggagcaag catcacacca tggcgtatga gtgttcctct gtgtagactc aacctgcgcc
61 tcgccgtccc ccattcgcac acccgatgcc cgggggtcgc tacggactta aaatctccgc
121 accgcaccct ccacctcaga aacgttcctg gatccgaaca ctgccccctg acgacctaga
181 gagatcccgg ctcccagccc actgagtggc ttcagcctcg ctgccccccg cccacttcat
241 ccctcaggca cctcccaact cctggcctct ctgcacgagg cgcctgcccc gggccccgcc
301 tacaggggac ccagctcttc ttgcagccac tggaagctga tcacctggag tgaagacctc
361 acacgaagaa gtctggaaga agaggaagag gaaagaaaag gagtcaggga tggcccttac
421 tcaggtacgg ttgacattta gggatgtggc catagaattc tctcaggagg agtggaaatg
481 cctggaccct gctcagagga tcttatacag ggacgtgatg ttggagaact actggaacct
541 tgtttctctg ggactgtgtc attttgatat gaatattatc tccatgttgg aggaagggaa
601 agagccctgg actgtgaaga gctgtgtgaa aatagcaaga aaaccaagaa cgccggaatg
661 tgtcaaaggc gtggtcacag acctgctcag gagatggaaa cattggctgc tgctccttgg
721 catctgctgc cccaaacctc atggaagagt ctccagccgt ctccgcctgt cgaggtccct
781 cggccatttc ttccattctg cttttgccac tttcatgggg gtgtgtgata agcgagtggg
841 ttctatcttc taagattgtt ctcagcataa ccgtaaagac acctaacaaa atccttctgt
901 cattgatcct cagtcttaca tggggtgcgt attctgtttt tccaggcttc agcacagaaa
961 tacaagtact gcatgttgtc acttacattt ggaatctaaa ccaataaaac taatagcagc
1021 aaagagtaga atgtgggtta ccacaggttg gggactggag ggaataggga gatgttggtc
1081 actgggtgaa aacattagga gtaaatgata ggtttttgag atgacttata tggtaatagg
1141 cttgtttcca tcagtccata ttgtatacct ataacagaat atcagtttgt ttcctgtaaa
1201 tatatataac tataatttgt caatatagaa tttttttaaa aatcatattc cagttcttat
1261 tgtgttggtt ctaaataaaa atgcttcttt ctcttaaaaa aaaaaaaaaa aa
＜110〉Attached Tongji Hospital, Tongji Univ.
＜120〉pulmonary thromboembolism related gene and application thereof
<160>142
<210>42
<211>2225
<212>DNA
＜213〉human (Homo sapiens)
<400>42
1 ggtttttgag cccattactg ttggagctac agggagagaa acagaggagg agactgcaag
61 agatcattgg aggccgtggg cacgctcttt actccatgtg tgggacattc attgcggaat
121 aacatcggag gagaagtttc ccagagctat ggggacttcc catccggcgt tcctggtctt
181 aggctgtctt ctcacagggc tgagcctaat cctctgccag ctttcattac cctctatcct
241 tccaaatgaa aatgaaaagg ttgtgcagct gaattcatcc ttttctctga gatgctttgg
301 ggagagtgaa gtgagctggc agtaccccat gtctgaagaa gagagctccg atgtggaaat
361 cagaaatgaa gaaaacaaca gcggcctttt tgtgacggtc ttggaagtga gcagtgcctc
421 ggcggcccac acagggttgt acacttgcta ttacaaccac actcagacag aagagaatga
481 gcttgaaggc aggcacattt acatctatgt gccagaccca gatgtagcct ttgtacctct
541 aggaatgacg gattatttag tcatcgtgga ggatgatgat tctgccatta taccttgtcg
601 cacaactgat cccgagactc ctgtaacctt acacaacagt gagggggtgg tacctgcctc
661 ctacgacagc agacagggct ttaatgggac cttcactgta gggccctata tctgtgaggc
721 caccgtcaaa ggaaagaagt tccagaccat cccatttaat gtttatgctt taaaaggtac
781 ttgtatcatc tccttccttc tttaaataag agtaacaggc aaaatcataa ggtgcgtgta
841 ggattttttt ttttttttaa atcatcatca ctggtgatcc taaattctga tttggggatt
901 taggacccca gctaatacaa tgtctgtggc tataataata agcttaaaat tactaaaggc
961 caaagcttga ttacccatgc aagatttcat gtttcatcag ttgacttcaa aatactgtaa
1021 ggaattcttt tcttacataa gcctcttact ttcattcaca ttcctgacta tggcggccct
1081 aaaaacaaac atacacccag ggggttagat gcctagatta attttagtaa cttaagaaaa
1141 gtgatttgaa gaaagtagtt tagacttcaa ccctttgatg tccacagtta gtacgcttgg
1201 ggaagtataa tacatgctga ggtcaacaga tatttcctga acactatatt acatggagga
1261 atgggtagca gcaagagtac actgttttaa aatcagagca cagctaattt tgtgccaggc
1321 actgtgctag gttctgggaa agtactgaga ataactgagg agcagagtgg aagagaagaa
1381 gagaagaaac aattggatag aaacaaagtg tctagagcag tgtggatcag caaatgttgg
1441 ttgattaaat gaataaattt attagtcaag gagattgtgg acgagtataa ccataactaa
1501 cccactgctg aggaatgcgg tgttctgttt gattggaatt tatttttatt gttattattt
1561 tgtaattctg tattataact atatgcctaa ttgttgtaca ccatctcaca atcaagcctt
1621 gtgagatttt ccaaatttta tcttgatcaa actggtttgc aaattatttt tcagggtttt
1681 cttaaaaaaa aaaaaaaaaa cccaaacttt ataagatcct ggctatcctg tggattttta
1741 ggcccttgta tttgttcttt tttatagcaa catcagagct ggatctagaa atggaagctc
1801 ttaaaaccgt gtataagtca ggggaaacga ttgtggtcac ctgtgctgtt tttaacaatg
1861 aggtggttga ccttcaatgg acttaccctg gagaagtggt aggtaccctc aaaacgtgca
1921 atggcttgga gcagagcaac agggctcaga agacctgcat ttgagctcgg tctgtcactg
1981 atgggcacat cactgagttt ctctagacct tagcttccca cctctgggat gaacacattt
2041 gattaaatgg cctttaggac tccttgatca atgggagagt ttgaaatgat agttcctgga
2101 ccaggccctt cagaatacat aaagagtgtg ccgtaagcct tctttttcag aaggcagaca
2161 gaaataggaa ggttctctgg ctacaagata tcaaccaaaa aaaaaaaaaa aaaaaaaaaa
2221 aaaaa
＜110〉Attached Tongji Hospital, Tongji Univ.
＜120〉pulmonary thromboembolism related gene and application thereof
<160>142
<210>43
<211>1108
<212>DNA
＜213〉human (Homo sapiens)
<400>43
1 aacagacagc agcgacttta ggctggataa tagtcaaatt cttacctcgc tctttcactg
61 ctagtaagat cagattgcgt tctttcagtt actcttcaat cgccagtttc ttgatctgct
121 tctaaaagaa gaagtagaga agataaatcc tgtcttcaat acctggaagg aaaaacaaaa
181 taacctcaac tccgttttga aaaaaacatt ccaagaactt tcatcagaga ttttacttag
241 atgatttaca caatgaagaa agtacatgca ctttgggctt ctgtatgcct gctgcttaat
301 cttgcccctg cccctcttaa tgctgattct gaggaagatg aagaacacac aattatcaca
361 gatacggagt tgccaccact gaaacttatg cattcatttt gtgcattcaa ggcggatgat
421 ggcccatgta aagcaatcat gaaaagattt ttcttcaata ttttcactcg acagtgcgaa
481 gaatttatat atgggggatg tgaaggaaat cagaatcgat ttgaaagtct ggaagagtgc
541 aaaaaaatgt gtacaagaga taatgcaaac aggattataa agacaacatt gcaacaagaa
601 aagccagatt tctgcttttt ggaagaagat cctggaatat gtcgaggtta tattaccagg
661 tatttttata acaatcagac aaaacagtgt gaacgtttca agtatggtgg atgcctgggc
721 aatatgaaca attttgagac actggaagaa tgcaagaaca tttgtgaaga tggtccgaat
781 ggtttccagg tggataatta tggaacccag ctcaatgctg tgaataactc cctgactccg
841 caatcaacca aggttcccag cctttttgtt acaaaagaag gaacaaatga tggttggaag
901 aatgcggctc atatttacca agtctttctg aacgccttct gcattcatgc atccatgttc
961 tttctaggat tggatagcat ttcatgccta tgttaatatt tgtgcttttg gcatttcctt
1021 aatatttata tgtatacgtg atgcctttga tagcatactg ctaataaagt tttaatattt
1081 acatgcaaaa aaaaaaaaaa aaaaaaaa
＜110〉Attached Tongji Hospital, Tongji Univ.
＜120〉pulmonary thromboembolism related gene and application thereof
<160>142
<210>44
<211>612
<212>DNA
＜213〉human (Homo sapiens)
<400>44
1 acactcgctt ctggaacgtc tgaggttatc aataagctcc tagtccagac gccatgggtc
61 atttcacaga ggaggacaag gctactatca caagcctgtg gggcaaggtg aatgtggaag
121 atgctggagg agaaaccctg ggaaggctcc tggttgtcta cccatggacc cagaggttct
181 ttgacagctt tggcaacctg tcctctgcct ctgccatcat gggcaacccc aaagtcaagg
241 cacatggcaa gaaggtgctg acttccttgg gagatgccat aaagcacctg gatgatctca
301 agggcacctt tgcccagctg agtgaactgc actgtgacaa gctgcatgtg gatcctgaga
361 acttcaagct cctgggaaat gtgctggtga ccgttttggc aatccatttc ggcaaagaat
421 tcacccctga ggtgcaggct tcctggcaga agatggtgac tgcagtggcc agtgccctgt
481 cctccagata ccactgagcc tcttgcccat gattcagagc tttcaaggat aggctttatt
541 ctgcaagcaa tacaaataat aaatctattc tgctgagaga tcaaaaaaaa aaaaaaaaaa
601 aaaaaaaaaa aa
＜110〉Attached Tongji Hospital, Tongji Univ.
＜120〉pulmonary thromboembolism related gene and application thereof
<160>142
<210>45
<211>2557
<212>DNA
＜213〉human (Homo sapiens)
<400>45
1 gccgagccca gctccccgcg gcggccgcta gcccccggcc ccgagccacc actccgacct
61 agcggccgcc gcccccggtg cgggatgagg agatccgcgg ccgccactgg gccccatgga
121 ggagccgcag ccgccccgcc caccagcgag catggcctta ctgggcagcc agcactccgg
181 cgccccctcc gcggccggcc cacctggcgg gacttcctcc gcggccacgg cggccgtgct
241 ctccttcagc accgtggcga ccgcggcgct ggggaacctg agcgacgcaa gcggaggcgg
301 cacagctgcc gctcccggtg gcggcggcct tggcgggtcc ggggcagcgc gggaggcggg
361 ggcggcggtg aggcggccgc taggcccgga ggcggcgccg ctgctgtcgc acggagctgc
421 agtggcggcc caggcgctcg tcctcctgct catcttcctg ctgtctagcc ttggcaactg
481 cgcggtgatg ggggtgattg tgaagcaccg gcagctccgc accgtcacca acgccttcat
541 cctgtcgctg tccctatcgg atctgctcac ggcgctgctc tgcctgcccg ccgccttcct
601 ggacctcttc actccgcccg ggggttcggc gcctgccgcc gccgcggggc cctggcgcgg
661 cttctgcgcc gccagccgct tcttcagctc gtgcttcggc atcgtgtcca cgctcagcgt
721 ggcgctcatc tcgttggacc gttactgcgc tatcgtgcgg ccgccgcggg agaagatcgg
781 ccgccgccgc gcgctgcagc tgctggcggg cgcctggctg acggccctgg gcttctcctt
841 gccctgggag ctgctcgggg cgccccggga actcgcggcg gcgcagagct tccacggctg
901 cctctaccgg acctccccgg accccgcgca gctgggcgcg gccttcagcg tggggctggt
961 ggtggcctgc tacctgctgc ccttcctgct catgtgcttc tgccactacc acatctgcaa
1021 gacggtgcgc ctgtcggacg tgcgcgtgcg gccggtgaac acctacgcgc gcgtgctgcg
1081 cttcttcagc gaggtgcgca cggccaccac cgtcctcatc atgatcgtct tcgtcatctg
1141 ctgctggggg ccctactgct tcctggtgct gctggccgcc gcccggcagg cccagaccat
1201 gcaggccccc tcgctcctca gcgtggtggc cgtctggctg acctgggcca atggggccat
1261 caaccctgtc atctacgcca tccgcaatcc caacatttcg atgctcctag ggcgcaaccg
1321 cgaggagggc taccggacta ggaatgtgga cgctttcctg cccagccagg gcccgggtct
1381 gcaagccaga agccgcagtc gccttcgaaa ccgctatgcc aaccggctgg gggcctgcaa
1441 caggatgtcc tcttccaacc cggccagcgg agtggcaggg gacgtggcca tgtgggcccg
1501 caaaaatcca gttgtacttt tctgccgaga gggaccacca gagccggtga cggcagtgac
1561 caaacagcct aaatccgaag ctggggatac cagcctctaa gacggttgga atggccagct
1621 tatgaaggca aatttccact cgcattattt aatgatggaa gattctgggg gagagttgtg
1681 gatttcataa agccaaacat ttaaagctag agacggggga ggcttaccac tttccccaaa
1741 caacataaaa gacaatgtcc cttcttcaaa agtgccaaaa ggaatgtaaa atgcaaaaat
1801 taaaacaatc ttaaaccaca taaccaagca ttgtgaactg ctatccaact atttagtggt
1861 agaactagga tttgaactgc agtctgtttg gcctcagaac tccatgtttg tttctctcta
1921 tccccacaga agtctacagg gcaacttcct gggagctaag gctactaaaa ggtagaagcc
1981 acagtactca tctgcagagg gcttacagcc tcagcaagga ccttgtggct ttgtaacaac
2041 aatcagccat aacaagttta cttgtggaaa agaaaaggtg tagcactttc agaagaggct
2101 atcaaagaaa agagatgaac ttggaagcaa gagatacgca gctcagcatg acagagactc
2161 cattccaggt ggaaaaagca catggctctt tcttctccga gatcccagga ctatcttatt
2221 ttcctcagag gggcaggtta caagaacttc acatctctca ggctacatgt tgcaaaggtt
2281 aaattccagg ttgtacgatt tttcacttcc accatcaagt tatgagtgtg attgtttccc
2341 tgcagttttg ccaatagagt gattttagac tatttacatc gtgggttaca accaatgtca
2401 gttattctgg ggaaacccaa ctgccatgtt gtgaggacac tcaagcagcc ctatggagga
2461 gcccacatgg tgagtgaata actacaagct gactctaatt ttaaaaaata aaaattttat
2521 ctctcaccaa ttttaaaatg acaaaaaaaa aaaaaaa
＜110〉Attached Tongji Hospital, Tongji Univ.
＜120〉pulmonary thromboembolism related gene and application thereof
<160>142
<210>46
<211>2475
<212>DNA
＜213〉human (Homo sapiens)
<400>46
1 agccgctctc cgcatcccag gacagcggtg cggccctcgg ccggggcgcc cactccgcag
61 cacccagcga gcgagcgagc gagcgagggc ggccgacgcg cccggccggg acccagctgc
121 ccgtatgacc gcgccgggcg ccgccgggcg ctgccctccc acgacatggc tgggctccct
181 gctgttgttg gtctgtctcc tggcgagcag gagtatcacc gaggaggtgt cggagtactg
241 tagccacatg attgggagtg gacacctgca gtctctgcag cggctgattg acagtcagat
301 ggagacctcg tgccaaatta catttgagtt tgtagaccag gaacagttga aagatccagt
361 gtgctacctt aagaaggcat ttctcctggt acaagacata atggaggaca ccatgcgctt
421 cagagataac acccccaatg ccatcgccat tgtgcagctg caggaactct ctttgaggct
481 gaagagctgc ttcaccaagg attatgaaga gcatgacaag gcctgcgtcc gaactttcta
541 tgagacacct ctccagttgc tggagaaggt caagaatgtc tttaatgaaa caaagaatct
601 ccttgacaag gactggaata ttttcagcaa gaactgcaac aacagctttg ctgaatgctc
661 cagccaagat gtggtgacca agcctgattg caactgcctg taccccaaag ccatccctag
721 cagtgacccg gcctctgtct cccctcatca gcccctcgcc ccctccatgg cccctgtggc
781 tggcttgacc tgggaggact ctgagggaac tgagggcagc tccctcttgc ctggtgagca
841 gcccctgcac acagtggatc caggcagtgc caagcagcgg ccacccagga gcacctgcca
901 gagctttgag ccgccagaga ccccagttgt caaggacagc accatcggtg gctcaccaca
961 gcctcgcccc tctgtcgggg ccttcaaccc cgggatggag gatattcttg actctgcaat
1021 gggcactaat tgggtcccag aagaagcctc tggagaggcc agtgagattc ccgtacccca
1081 agggacagag ctttccccct ccaggccagg agggggcagc atgcagacag agcccgccag
1141 acccagcaac ttcctctcag catcttctcc actccctgca tcagcaaagg gccaacagcc
1201 ggcagatgta actggtaccg ccttgcccag ggtgggcccc gtgaggccca ctggccagga
1261 ctggaatcac accccccaga agacagacca tccatctgcc ctgctcagag accccccgga
1321 gccaggctct cccaggatct catcaccgcg cccccagggc ctcagcaacc cctccaccct
1381 ctctgctcag ccacagcttt ccagaagcca ctcctcgggc agcgtgctgc cccttgggga
1441 gctggagggc aggaggagca ccagggatcg gaggagcccc gcagagccag aaggaggacc
1501 agcaagtgaa ggggcagcca ggcccctgcc ccgttttaac tccgttcctt tgactgacac
1561 acatgagagg cagtccgagg gatcctccag cccgcagctc caggagtctg tcttccacct
1621 gctggtgccc agtgtcatcc tggtcttgct ggccgtcgga ggcctcttgt tctacaggtg
1681 gaggcggcgg agccatcaag agcctcagag agcggattct cccttggagc aaccagaggg
1741 cagccccctc actcaggatg acagacaggt ggaactgcca gtgtagaggg aattctaaga
1801 cccctcacca tcctggacac tctcgtttgt caatgtccct ctgaaaatgt gacgcccagc
1861 cccggacaca gtactccaga tgttgtctga ccagctcaga gagagtacag tgggactgtt
1921 accttccttg atatggacag tattcttcta tttgtgcaga ttaagattgc attagttcct
1981 ttcttaacaa ctgcatcata ctgttgtcat atgttgagcc tgtggtctat aaaaccccca
2041 gttccatttc ccataaactt ctgtcaagcc agaccatctc taccctgtac ttggacaact
2101 taactttttt aaccaaagtg cagtttatgt tcacctttgt taaagccagc ttgtggtttc
2161 tgcccatcac ctgaacctac tgaagttgtg tgaaatccta attctgtcat ctccgtagcc
2221 ctcccagttg tgcctcctgc acattgatga gtgcctgctg ttgtctttgc ccatgttgtt
2281 gatgtagctg tgaccctatt gttcctcacc cctgcccccc gccaacccca gctggcccac
2341 ctcttccccc tcccacccaa gcccacagcc agcccatcag gaagccttcc tggcttctcc
2401 acaaccttct gactgtcttt tcagtcatgc cccctgctct tttgtatttg gctaatagta
2461 tatcaatttg cactt
＜110〉Attached Tongji Hospital, Tongji Univ.
＜120〉pulmonary thromboembolism related gene and application thereof
<160>142
<210>47
<211>1983
<212>DNA
＜213〉human (Homo sapiens)
<400>47
1 gaggactgca gtgtaggact ttcctgcaga ataccatttg atcctattaa gaattgtcca
61 aatgttggag catttgattg aaaaatcctt cttagccatt ttaaagatag ctttccaatg
121 attagacgaa ttgattcttt ctgtgactca tcagttcatt tcctgtaaaa ttcatgtctt
181 gctgttgatt tgtgaataag aaccagagct tgtagaaacc actttaatca tatcgaggag
241 tttgcaagaa acaggtgctt aacactaatt cacctcctga acaagaaaaa tgggctgtga
301 ccggaactgt gggctcatcg ctggggctgt cattggtgct gtcctggctg tgtttggagg
361 tattctaatg ccagttggag acctgcttat ccagaagaca attaaaaagc aagttgtcct
421 cgaagaaggt acaattgctt ttaaaaattg ggttaaaaca ggcacagaag tttacagaca
481 gttttggatc tttgatgtgc aaaatccaca ggaagtgatg atgaacagca gcaacattca
541 agttaagcaa agaggtcctt atacgtacag agttcgtttt ctagccaagg aaaatgtaac
601 ccaggacgct gaggacaaca cagtctcttt cctgcagccc aatggtgcca tcttcgaacc
661 ttcactatca gttggaacag aggctgacaa cttcacagtt ctcaatctgg ctgtggcagc
721 tgcatcccat atctatcaaa atcaatttgt tcaaatgatc ctcaattcac ttattaacaa
781 gtcaaaatct tctatgttcc aagtcagaac tttgagagaa ctgttatggg gctataggga
841 tccatttttg agtttggttc cgtaccctgt tactaccaca gttggtctgt tttatcctta
901 caacaatact gcagatggag tttataaagt tttcaatgga aaagataaca taagtaaagt
961 tgccataatc gacacatata aaggtaaaag gaatctgtcc tattgggaaa gtcactgcga
1021 catgattaat ggtacagatg cagcctcatt tccacctttt gttgagaaaa gccaggtatt
1081 gcagttcttt tcttctgata tttgcaggtc aatctatgct gtatttgaat ccgacgttaa
1141 tctgaaagga atccctgtgt atagatttgt tcttccatcc aaggcctttg cctctccagt
1201 tgaaaaccca gacaactatt gtttctgcac agaaaaaatt atctcaaaaa attgtacatc
1261 atatggtgtg ctagacatca gcaaatgcaa agaagggaga cctgtgtaca tttcacttcc
1321 tcattttctg tatgcaagtc ctgatgtttc agaacctatt gatggattaa acccaaatga
1381 agaagaacat aggacatact tggatattga acctataact ggattcactt tacaatttgc
1441 aaaacggctg caggtcaacc tattggtcaa gccatcagaa taaattcaag tattaaagaa
1501 tctgaagagg aactatattg tgcctattct ttggcttaat gagactggga ccattggtga
1561 tgagaaggca aacatgttca gaagtcaagt aactggaaaa ataaacctcc ttggcctgat
1621 agaaatgatc ttactcagtg ttggtgtggt gatgtttgtt gcttttatga tttcatattg
1681 tgcatgcaga tcgaaaacaa taaaataagt aagtatgtac caaaaaatat tgcttcaata
1741 atattagctt atatattact tgttttcact ttatcaaaga gaagttacat attaggccat
1801 atatatttct agacatgtct agccactgat catttttaaa tataggtaaa taaacctata
1861 aatattatca cgcagatcac taaagtatat ctttaattct gggagaaatg agataaaaga
1921 tgtacttgtg accattgtaa caatagcaca aataaagcac ttgtgccaaa gttgtccaaa
1981 aaa
＜110〉Attached Tongji Hospital, Tongji Univ.
＜120〉pulmonary thromboembolism related gene and application thereof
<160>142
<210>48
<211>2217
<212>DNA
＜213〉human (Homo sapiens)
<400>48
1 tgctgtactg agagagaatg ttacataaca ttgagaacta gtacaagtaa atattaaagt
61 gaagtgacca tttcctacac aagctcattc agaggaggat gaagaccatt ttggaggaag
121 aaaagcaccc ttattaagaa ttgcagcaag taagccaaca aggtcttttc aggatgattt
181 tcttatatca agtggtacat ttcattttat ttacttcagt ttctggtgaa tgtgtgactc
241 agttgttgaa ggacacctgc tttgaaggag gggacattac tacggtcttc acaccaagcg
301 ccaagtactg ccaggtagtc tgcacttacc acccaagatg tttactcttc actttcacgg
361 cggaatcacc atctgaggat cccacccgat ggtttacttg tgtcctgaaa gacagtgtta
421 cagaaacact gccaagagtg aataggacag cagcgatttc tgggtattct ttcaagcaat
481 gctcacacca aataagcgct tgcaacaaag acatttatgt ggacctagac atgaagggca
541 taaactataa cagctcagtt gccaagagtg ctcaagaatg ccaagaaaga tgcacggatg
601 acgtccactg ccactttttc acgtacgcca caaggcagtt tcccagcctg gagcatcgta
661 acatttgtct actgaagcac acccaaacag ggacaccaac cagaataacg aagctcgata
721 aagtggtgtc tggattttca ctgaaatcct gtgcactttc taatctggct tgtattaggg
781 acattttccc taatacggtg tttgcagaca gcaacatcga cagtgtcatg gctcccgatg
841 cttttgtctg tggccgaatc tgcactcatc atcccggttg cttgtttttt accttctttt
901 cccaggaatg gcccaaagaa tctcaaagaa atctttgtct ccttaaaaca tctgagagtg
961 gattgcccag tacacgcatt aaaaagagca aagctctttc tggtttcagt ctacaaagct
1021 gcaggcacag catcccagtg ttctgccatt cttcatttta ccatgacact gatttcttgg
1081 gagaagaact ggatattgtt gctgcaaaaa gtcacgaggc ctgccagaaa ctgtgcacca
1141 atgccgtccg ctgccagttt tttacctata ccccagccca agcatcctgc aacgaaggga
1201 agggcaagtg ttacttaaag ctttcttcaa acggatctcc aactaaaata cttcacggga
1261 gaggaggcat ctctggatac acattaaggt tgtgtaaaat ggataatgag tgtaccacca
1321 aaatcaagcc caggatcgtt ggaggaactg cgtctgttcg tggtgagtgg ccgtggcagg
1381 tgaccctgca cacaacctca cccactcaga gacacctgtg tggaggctcc atcattggaa
1441 accagtggat attaacagcc gctcactgtt tctatggggt agagtcacct aagattttgc
1501 gtgtctacag tggcatttta aatcaatctg aaataaaaga ggacacatct ttctttgggg
1561 ttcaagaaat aataatccat gatcagtata aaatggcaga aagcgggtat gatattgcct
1621 tgttgaaact ggaaaccaca gtgaattaca cagattctca acgacccata tgcctgcctt
1681 ccaaaggaga tagaaatgta atatacactg attgctgggt gactggatgg gggtacagaa
1741 aactaagaga caaaatacaa aatactctcc agaaagccaa gataccctta gtgaccaacg
1801 aagagtgcca gaagagatac agaggacata aaataaccca taagatgatc tgtgccggct
1861 acagggaagg agggaaggac gcttgcaagg gagattcggg aggccctctg tcctgcaaac
1921 acaatgaggt ctggcatctg gtaggcatca cgagctgggg cgaaggctgt gctcaaaggg
1981 agcggccagg tgtttacacc aacgtggtcg agtacgtgga ctggattctg gagaaaactc
2041 aagcagtgtg aatgggttcc caggggccat tggagtccct gaaggaccca ggatttgctg
2101 ggagagggtg ttgagttcac tgtgccagca tgcttcctcc acagtaacac gctgaagggg
2161 cttggtgttt gtaagaaaat gctagaagaa aacaaactgt cacaagttgt tatgtcc
＜110〉Attached Tongji Hospital, Tongji Univ.
＜120〉pulmonary thromboembolism related gene and application thereof
<160>142
<210>49
<211>6914
<212>DNA
＜213〉human (Homo sapiens)
<400>49
1 tcattgcagc tgggacagcc cggagtgtgg ttagcagctc ggcaagcgct gcccaggtcc
61 tggggtggtg gcagccagcg ggagcaggaa aggaagcatg ttcccaggct gcccacgcct
121 ctgggtcctg gtggtcttgg gcaccagctg ggtaggctgg gggagccaag ggacagaagc
181 ggcacagcta aggcagttct acgtggctgc tcagggcatc agttggagct accgacctga
241 gcccacaaac tcaagtttga atctttctgt aacttccttt aagaaaattg tctacagaga
301 gtatgaacca tattttaaga aagaaaaacc acaatctacc atttcaggac ttcttgggcc
361 tactttatat gctgaagtcg gagacatcat aaaagttcac tttaaaaata aggcagataa
421 gcccttgagc atccatcctc aaggaattag gtacagtaaa ttatcagaag gtgcttctta
481 ccttgaccac acattccctg cagagaagat ggacgacgct gtggctccag gccgagaata
541 cacctatgaa tggagtatca gtgaggacag tggacccacc catgatgacc ctccatgcct
601 cacacacatc tattactccc atgaaaatct gatcgaggat ttcaactctg ggctgattgg
661 gcccctgctt atctgtaaaa aagggaccct aactgagggt gggacacaga agacgtttga
721 caagcaaatc gtgctactat ttgctgtgtt tgatgaaagc aagagctgga gccagtcatc
781 atccctaatg tacacagtca atggatatgt gaatgggaca atgccagata taacagtttg
841 tgcccatgac cacatcagct ggcatctgct gggaatgagc tcggggccag aattattctc
901 cattcatttc aacggccagg tcctggagca gaaccatcat aaggtctcag ccatcaccct
961 tgtcagtgct acatccacta ccgcaaatat gactgtgggc ccagagggaa agtggatcat
1021 atcttctctc accccaaaac atttgcaagc tgggatgcag gcttacattg acattaaaaa
1081 ctgcccaaag aaaaccagga atcttaagaa aataactcgt gagcagaggc ggcacatgaa
1141 gaggtgggaa tacttcattg ctgcagagga agtcatttgg gactatgcac ctgtaatacc
1201 agcgaatatg gacaaaaaat acaggtctca gcatttggat aatttctcaa accaaattgg
1261 aaaacattat aagaaagtta tgtacacaca gtacgaagat gagtccttca ccaaacatac
1321 agtgaatccc aatatgaaag aagatgggat tttgggtcct attatcagag cccaggtcag
1381 agacacactc aaaatcgtgt tcaaaaatat ggccagccgc ccctatagca tttaccctca
1441 tggagtgacc ttctcgcctt atgaagatga agtcaactct tctttcacct caggcaggaa
1501 caacaccatg atcagagcag ttcaaccagg ggaaacctat acttataagt ggaacatctt
1561 agagtttgat gaacccacag aaaatgatgc ccagtgctta acaagaccat actacagtga
1621 cgtggacatc atgagagaca tcgcctctgg gctaatagga ctacttctaa tctgtaagag
1681 cagatccctg gacaggcgag gaatacagag ggcagcagac atcgaacagc aggctgtgtt
1741 tgctgtgttt gatgagaaca aaagctggta ccttgaggac aacatcaaca agttttgtga
1801 aaatcctgat gaggtgaaac gtgatgaccc caagttttat gaatcaaaca tcatgagcac
1861 tatcaatggc tatgtgcctg agagcataac tactcttgga ttctgctttg atgacactgt
1921 ccagtggcac ttctgtagtg tggggaccca gaatgaaatt ttgaccatcc acttcactgg
1981 gcactcattc atctatggaa agaggcatga ggacaccttg accctcttcc ccatgcgtgg
2041 agaatctgtg acggtcacaa tggataatgt tggaacttgg atgttaactt ccatgaattc
2101 tagtccaaga agcaaaaagc tgaggctgaa attcagggat gttaaatgta tcccagatga
2161 tgatgaagac tcatatgaga tttttgaacc tccagaatct acagtcatgg ctacacggaa
2221 aatgcatgat cgtttagaac ctgaagatga agagagtgat gctgactatg attaccagaa
2281 cagactggct gcagcattag gaattaggtc attccgaaac tcatcattga accaggaaga
2341 agaagagttc aatcttactg ccctagctct ggagaatggc actgaattcg tttcttcgaa
2401 cacagatata attgttggtt caaattattc ttccccaagt aatattagta agttcactgt
2461 caataacctt gcagaacctc agaaagcccc ttctcaccaa caagccacca cagctggttc
2521 cccactgaga cacctcattg gcaagaactc agttctcaat tcttccacag cagagcattc
2581 cagcccatat tctgaagacc ctatagagga tcctctacag ccagatgtca cagggatacg
2641 tctactttca cttggtgctg gagaattcag aagtcaagaa catgctaagc gtaagggacc
2701 caaggtagaa agagatcaag cagcaaagca caggttctcc tggatgaaat tactagcaca
2761 taaagttggg agacacctaa gccaagacac tggttctcct tccggaatga ggccctggga
2821 ggaccttcct agccaagaca ctggttctcc ttccagaatg aggccctggg aggaccctcc
2881 tagtgatctg ttactcttaa aacaaagtaa ctcatctaag attttggttg ggagatggca
2941 tttggcttct gagaaaggta gctatgaaat aatccaagat actgatgaag acacagctgt
3001 taacaattgg ctgatcagcc cccagaatgc ctcacgtgct tggggagaaa gcacccctct
3061 tgccaacaag cctggaaagc agagtggcca cccaaagttt cctagagtta gacataaatc
3121 tctacaagta agacaggatg gaggaaagag tagactgaag aaaagccagt ttctcattaa
3181 gacacgaaaa aagaaaaaag agaagcacac acaccatgct cctttatctc cgaggacctt
3241 tcaccctcta agaagtgaag cctacaacac attttcagaa agaagactta agcattcgtt
3301 ggtgcttcat aaatccaatg aaacatctct tcccacagac ctcaatcaga cattgccctc
3361 tatggatttt ggctggatag cctcacttcc tgaccataat cagaattcct caaatgacac
3421 tggtcaggca agctgtcctc caggtcttta tcagacagtg cccccagagg aacactatca
3481 aacattcccc attcaagacc ctgatcaaat gcactctact tcagacccca gtcacagatc
3541 ctcttctcca gagctcagtg aaatgcttga gtatgaccga agtcacaagt ccttccccac
3601 agatataagt caaatgtccc cttcctcaga acatgaagtc tggcagacag tcatctctcc
3661 agacctcagc caggtgaccc tctctccaga actcagccag acaaacctct ctccagacct
3721 cagccacacg actctctctc cagaactcat tcagagaaac ctttccccag ccctcggtca
3781 gatgcccatt tctccagacc tcagccatac aaccctttct ccagacctca gccatacaac
3841 cctttcttta gacctcagcc agacaaacct ctctccagaa ctcagtcaga caaacctttc
3901 tccagccctc ggtcagatgc ccctttctcc agacctcagc catacaacca tttctctaga
3961 cttcagccag acaaacctct ctccagaact cagccatatg actctctctc cagaactcag
4021 tcagacaaac ctttccccag ccctcggtca gatgcccatt tctccagacc tcagccatac
4081 aaccctttct ctagacttca gccagacaaa cctctctcca gaactcagtc aaacaaacct
4141 ttccccagcc ctcggtcaga tgcccctttc tccagacccc agccatacaa ccctttctct
4201 agacctcagc cagacaaacc tctctccaga actcagtcag acaaaccttt ccccagacct
4261 cagtgagatg cccctctttg cagatctcag tcaaattccc cttaccccag acctcgacca
4321 gatgacactt tctccagacc ttggtgagac agatctttcc ccaaactttg gtcagatgtc
4381 cctttcccca gacctcagcc aggtgactct ctctccagac atcagtgaca ccacccttct
4441 cccggatctc agccagatat cacctcctcc agaccttgat cagatattct acccttctga
4501 atctagtcag tcattgcttc ttcaagaatt taatgagtct tttccttatc cagaccttgg
4561 tcagatgcca tctccttcat ctcctactct caatgatact tttctatcaa aggaatttaa
4621 tccactggtt atagtgggcc tcagtaaaga tggtacagat tacattgaga tcattccaaa
4681 ggaagaggtc cagagcagtg aagatgacta tgctgaaatt gattatgtgc cctatgatga
4741 cccctacaaa actgatgtta ggacaaacat caactcctcc agagatcctg acaacattgc
4801 agcatggtac ctccgcagca acaatggaaa cagaagaaat tattacattg ctgctgaaga
4861 aatatcctgg gattattcag aatttgtaca aagggaaaca gatattgaag actctgatga
4921 tattccagaa gataccacat ataagaaagt agtttttcga aagtacctcg acagcacttt
4981 taccaaacgt gatcctcgag gggagtatga agagcatctc ggaattcttg gtcctattat
5041 cagagctgaa gtggatgatg ttatccaagt tcgttttaaa aatttagcat ccagaccgta
5101 ttctctacat gcccatggac tttcctatga aaaatcatca gagggaaaga cttatgaaga
5161 tgactctcct gaatggttta aggaagataa tgctgttcag ccaaatagca gttataccta
5221 cgtatggcat gccactgagc gatcagggcc agaaagtcct ggctctgcct gtcgggcttg
5281 ggcctactac tcagctgtga acccagaaaa agatattcac tcaggcttga taggtcccct
5341 cctaatctgc caaaaaggaa tactacataa ggacagcaac atgcctgtgg acatgagaga
5401 atttgtctta ctatttatga cctttgatga aaagaagagc tggtactatg aaaagaagtc
5461 ccgaagttct tggagactca catcctcaga aatgaaaaaa tcccatgagt ttcacgccat
5521 taatgggatg atctacagct tgcctggcct gaaaatgtat gagcaagagt gggtgaggtt
5581 acacctgctg aacataggcg gctcccaaga cattcacgtg gttcactttc acggccagac
5641 cttgctggaa aatggcaata aacagcacca gttaggggtc tggccccttc tgcctggttc
5701 atttaaaact cttgaaatga aggcatcaaa acctggctgg tggctcctaa acacagaggt
5761 tggagaaaac cagagagcag ggatgcaaac gccatttctt atcatggaca gagactgtag
5821 gatgccaatg ggactaagca ctggtatcat atctgattca cagatcaagg cttcagagtt
5881 tctgggttac tgggagccca gattagcaag attaaacaat ggtggatctt ataatgcttg
5941 gagtgtagaa aaacttgcag cagaatttgc ctctaaacct tggatccagg tggacatgca
6001 aaaggaagtc ataatcacag ggatccagac ccaaggtgcc aaacactacc tgaagtcctg
6061 ctataccaca gagttctatg tagcttacag ttccaaccag atcaactggc agatcttcaa
6121 agggaacagc acaaggaatg tgatgtattt taatggcaat tcagatgcct ctacaataaa
6181 agagaatcag tttgacccac ctattgtggc tagatatatt aggatctctc caactcgagc
6241 ctataacaga cctacccttc gattggaact gcaaggttgt gaggtaaatg gatgttccac
6301 acccctgggt atggaaaatg gaaagataga aaacaagcaa atcacagctt cttcgtttaa
6361 gaaatcttgg tggggagatt actgggaacc cttccgtgcc cgtctgaatg cccagggacg
6421 tgtgaatgcc tggcaagcca aggcaaacaa caataagcag tggctagaaa ttgatctact
6481 caagatcaag aagataacgg caattataac acagggctgc aagtctctgt cctctgaaat
6541 gtatgtaaag agctatacca tccactacag tgagcaggga gtggaatgga aaccatacag
6601 gctgaaatcc tccatggtgg acaagatttt tgaaggaaat actaatacca aaggacatgt
6661 gaagaacttt ttcaaccccc caatcatttc caggtttatc cgtgtcattc ctaaaacatg
6721 gaatcaaagt attgcacttc gcctggaact ctttggctgt gatatttact agaattgaac
6781 attcaaaaac ccctggaaga gactctttaa gacctcaaac catttagaat gggcaatgta
6841 ttttacgctg tgttaaatgt taacagtttt ccactatttc tctttctttt ctattagtga
6901 ataaaatttt atac
＜110〉Attached Tongji Hospital, Tongji Univ.
＜120〉pulmonary thromboembolism related gene and application thereof
<160>142
<210>50
<211>2478
<212>DNA
＜213〉human (Homo sapiens)
<400>50
1 agtcccatgg ggaatgtcaa caggcagggg cagcactgca gagatttcat catggtctcc
61 caggccctca ggctcctctg ccttctgctt gggcttcagg gctgcctggc tgcaggcggg
121 gtcgctaagg cctcaggagg agaaacacgg gacatgccgt ggaagccggg gcctcacaga
181 gtcttcgtaa cccaggagga agcccacggc gtcctgcacc ggcgccggcg cgccaacgcg
241 ttcctggagg agctgcggcc gggctccctg gagagggagt gcaaggagga gcagtgctcc
301 ttcgaggagg cccgggagat cttcaaggac gcggagagga cgaagctgtt ctggatttct
361 tacagtgatg gggaccagtg tgcctcaagt ccatgccaga atgggggctc ctgcaaggac
421 cagctccagt cctatatctg cttctgcctc cctgccttcg agggccggaa ctgtgagacg
481 cacaaggatg accagctgat ctgtgtgaac gagaacggcg gctgtgagca gtactgcagt
541 gaccacacgg gcaccaagcg ctcctgtcgg tgccacgagg ggtactctct gctggcagac
601 ggggtgtcct gcacacccac agttgaatat ccatgtggaa aaatacctat tctagaaaaa
661 agaaatgcca gcaaacccca aggccgaatt gtggggggca aggtgtgccc caaaggggag
721 tgtccatggc aggtcctgtt gttggtgaat ggagctcagt tgtgtggggg gaccctgatc
781 aacaccatct gggtggtctc cgcggcccac tgtttcgaca aaatcaagaa ctggaggaac
841 ctgatcgcgg tgctgggcga gcacgacctc agcgagcacg acggggatga gcagagccgg
901 cgggtggcgc aggtcatcat ccccagcacg tacgtcccgg gcaccaccaa ccacgacatc
961 gcgctgctcc gcctgcacca gcccgtggtc ctcactgacc atgtggtgcc cctctgcctg
1021 cccgaacgga cgttctctga gaggacgctg gccttcgtgc gcttctcatt ggtcagcggc
1081 tggggccagc tgctggaccg tggcgccacg gccctggagc tcatggtgct caacgtgccc
1141 cggctgatga cccaggactg cctgcagcag tcacggaagg tgggagactc cccaaatatc
1201 acggagtaca tgttctgtgc cggctactcg gatggcagca aggactcctg caagggggac
1261 agtggaggcc cacatgccac ccactaccgg ggcacgtggt acctgacggg catcgtcagc
1321 tggggccagg gctgcgcaac cgtgggccac tttggggtgt acaccagggt ctcccagtac
1381 atcgagtggc tgcaaaagct catgcgctca gagccacgcc caggagtcct cctgcgagcc
1441 ccatttccct agcccagcag ccctggcctg tggagagaaa gccaaggctg cgtcgaactg
1501 tcctggcacc aaatcccata tattcttctg cagttaatgg ggtagaggag ggcatgggag
1561 ggagggagag gtggggaggg agacagagac agaaacagag agagacagag acagagagag
1621 actgagggag agactctgag gacatggaga gagactcaaa gagactccaa gattcaaaga
1681 gactaataga gacacagaga tggaatagaa aagatgagag gcagaggcag acaggcgctg
1741 gacagagggg caggggagtg ccaaggttgt cctggaggca gacagcccag ctgagcctcc
1801 ttacctccct tcagccaagc cccacctgca cgtgatctgc tggccctcag gctgctgctc
1861 tgccttcatt gctggagaca gtagaggcat gaacacacat ggatgcacac acacacacgc
1921 caatgcacac acacagagat atgcacacac acggatgcac acacagatgg tcacacagag
1981 atacgcaaac acaccgatgc acacgcacat agagatatgc acacacagat gcacacacag
2041 atatacacat ggatgcacgc acatgccaat gcacgcacac atcagtgcac acggatgcac
2101 agagatatgc acacaccgat gtgcgcacac acagatatgc acacacatgg atgagcacac
2161 acacaccaag tgcgcacaca caccgatgta cacacacaga tgcacacaca gatgcacaca
2221 caccgatgct gactccatgt gtgctgtcct ctgaaggcgg ttgtttagct ctcacttttc
2281 tggttcttat ccattatcat cttcacttca gacaattcag aagcatcacc atgcatggtg
2341 gcgaatgccc ccaaactctc ccccaaatgt atttctccct tcgctgggtg ccgggctgca
2401 cagactattc cccacctgct tcccagcttc acaataaacg gctgcgtctc ctccgcacac
2461 ctgtggtgcc tgccaccc
＜110〉Attached Tongji Hospital, Tongji Univ.
＜120〉pulmonary thromboembolism related gene and application thereof
<160>142
<210>51
<211>2804
<212>DNA
＜213〉human (Homo sapiens)
<400>51
1 accactttca caatctgcta gcaaaggtta tgcagcgcgt gaacatgatc atggcagaat
61 caccaggcct catcaccatc tgccttttag gatatctact cagtgctgaa tgtacagttt
121 ttcttgatca tgaaaacgcc aacaaaattc tgaatcggcc aaagaggtat aattcaggta
181 aattggaaga gtttgttcaa gggaaccttg agagagaatg tatggaagaa aagtgtagtt
241 ttgaagaagc acgagaagtt tttgaaaaca ctgaaagaac aactgaattt tggaagcagt
301 atgttgatgg agatcagtgt gagtccaatc catgtttaaa tggcggcagt tgcaaggatg
361 acattaattc ctatgaatgt tggtgtccct ttggatttga aggaaagaac tgtgaattag
421 atgtaacatg taacattaag aatggcagat gcgagcagtt ttgtaaaaat agtgctgata
481 acaaggtggt ttgctcctgt actgagggat atcgacttgc agaaaaccag aagtcctgtg
541 aaccagcagt gccatttcca tgtggaagag tttctgtttc acaaacttct aagctcaccc
601 gtgctgagac tgtttttcct gatgtggact atgtaaattc tactgaagct gaaaccattt
661 tggataacat cactcaaagc acccaatcat ttaatgactt cactcgggtt gttggtggag
721 aagatgccaa accaggtcaa ttcccttggc aggttgtttt gaatggtaaa gttgatgcat
781 tctgtggagg ctctatcgtt aatgaaaaat ggattgtaac tgctgcccac tgtgttgaaa
841 ctggtgttaa aattacagtt gtcgcaggtg aacataatat tgaggagaca gaacatacag
901 agcaaaagcg aaatgtgatt cgaattattc ctcaccacaa ctacaatgca gctattaata
961 agtacaacca tgacattgcc cttctggaac tggacgaacc cttagtgcta aacagctacg
1021 ttacacctat ttgcattgct gacaaggaat acacgaacat cttcctcaaa tttggatctg
1081 gctatgtaag tggctgggga agagtcttcc acaaagggag atcagcttta gttcttcagt
1141 accttagagt tccacttgtt gaccgagcca catgtcttcg atctacaaag ttcaccatct
1201 ataacaacat gttctgtgct ggcttccatg aaggaggtag agattcatgt caaggagata
1261 gtgggggacc ccatgttact gaagtggaag ggaccagttt cttaactgga attattagct
1321 ggggtgaaga gtgtgcaatg aaaggcaaat atggaatata taccaaggta tcccggtatg
1381 tcaactggat taaggaaaaa acaaagctca cttaatgaaa gatggatttc caaggttaat
1441 tcattggaat tgaaaattaa cagggcctct cactaactaa tcactttccc atcttttgtt
1501 agatttgaat atatacattc tatgatcatt gctttttctc tttacagggg agaatttcat
1561 attttacctg agcaaattga ttagaaaatg gaaccactag aggaatataa tgtgttagga
1621 aattacagtc atttctaagg gcccagccct tgacaaaatt gtgaagttaa attctccact
1681 ctgtccatca gatactatgg ttctccacta tggcaactaa ctcactcaat tttccctcct
1741 tagcagcatt ccatcttccc gatcttcttt gcttctccaa ccaaaacatc aatgtttatt
1801 agttctgtat acagtacagg atctttggtc tactctatca caaggccagt accacactca
1861 tgaagaaaga acacaggagt agctgagagg ctaaaactca tcaaaaacac tactcctttt
1921 cctctaccct attcctcaat cttttacctt ttccaaatcc caatccccaa atcagttttt
1981 ctctttctta ctccctctct cccttttacc ctccatggtc gttaaaggag agatggggag
2041 catcattctg ttatacttct gtacacagtt atacatgtct atcaaaccca gacttgcttc
2101 catagtggag acttgctttt cagaacatag ggatgaagta aggtgcctga aaagtttggg
2161 ggaaaagttt ctttcagaga gttaagttat tttatatata taatatatat ataaaatata
2221 taatatacaa tataaatata tagtgtgtgt gtgtatgcgt gtgtgtagac acacacgcat
2281 acacacatat aatggaagca ataagccatt ctaagagctt gtatggttat ggaggtctga
2341 ctaggcatga tttcacgaag gcaagattgg catatcattg taactaaaaa agctgacatt
2401 gacccagaca tattgtactc tttctaaaaa taataataat aatgctaaca gaaagaagag
2461 aaccgttcgt ttgcaatcta cagctagtag agactttgag gaagaattca acagtgtgtc
2521 ttcagcagtg ttcagagcca agcaagaagt tgaagttgcc tagaccagag gacataagta
2581 tcatgtctcc tttaactagc ataccccgaa gtggagaagg gtgcagcagg ctcaaaggca
2641 taagtcattc caatcagcca actaagttgt ccttttctgg tttcgtgttc accatggaac
2701 attttgatta tagttaatcc ttctatcttg aatcttctag agagttgctg accaactgac
2761 gtatgtttcc ctttgtgaat taataaactg gtgttctggt tcat
＜110〉Attached Tongji Hospital, Tongji Univ.
＜120〉pulmonary thromboembolism related gene and application thereof
<160>142
<210>52
<211>2941
<212>DNA
＜213〉human (Homo sapiens)
<400>52
1 cctgtggccg ctcccggctc ggagtgtgat ctaagcaggt tgcgtacctt cctcaggtga
61 ctccggccac agcccattgt ccgcggccac cggcggagtt tagccgcaga cctcgaagcg
121 ccccggggtc cttcccgaac ggcagcggct gcggcgggtc catggagaag ggccctgtgc
181 gggcaccggc ggagaagccg cggggcgcca ggtgcagcaa tgggttcccc gagcgggatc
241 cgccgcggcc cgggcccagc aggccggcgg agaagccccc gcggcccgag gccaagagcg
301 cgcagcccgc ggacggctgg aagggcgagc ggccccgcag cgaggaggat aacgagctga
361 acctccctaa cctggcagcc gcctactcgt ccatcctgag ctcgctgggc gagaaccccc
421 agcggcaagg gctgctcaag acgccctgga gggcggcctc ggccatgcag ttcttcacca
481 agggctacca ggagactatc tcagatgtcc taaacgatgc tatatttgat gaagatcatg
541 atgagatggt gattgtgaag gacatagaca tgttttccat gtgtgagcat cacttggttc
601 catttgttgg aaaggtccat attggttatc ttcctaacaa gcaagtcctt ggcctcagca
661 aacttgcgag gattgtagaa atctatagta gaagactaca agttcaggag cgccttacaa
721 aacaaattgc tgtagcaatc acggaagcct tgcggcctgc tggagtcggg gtagtggttg
781 aagcaacaca catgtgtatg gtaatgcgag gtgtacagaa aatgaacagc aaaactgtga
841 ccagcacaat gttgggtgtg ttccgggagg atccaaagac tcgggaagag ttcctgactc
901 tcattaggag ctgagcttca ttcagtgtgt gtgcgttggt tgccgatcgt actgccagta
961 gcattgtctg tctgtccggt cttgtttgta cattccattt tcaattgtta cagatgtgaa
1021 ctttattcct tgtcactaat tatatttaaa attatttcta ggaagtcaaa taaatataat
1081 aaagggttga gccctctact ttcttcttgc cacctttttg tggcaatatt aaagtgaact
1141 gctaatagtg taagtacgtg cacaaaacca ctgccagata accagagggg cctgggaagg
1201 gagaagaatt agtgtatttt tttcaaatag tacagtaatt tgcctcataa gcataggagc
1261 attgggaatg agagggaact gtgcccagta tactgttttt tttcttcctc caataaaagt
1321 ggtgtagtgc cgaaagtgct aaaatattta gtgcggtatt gctctgtgaa ttcaagttca
1381 acagacttca ctttggtcat gtttattaaa ccaccagtga catttaaaaa tatattttta
1441 gcagtcgtaa tgttagtcac caagggaagg tggtggaatg tctatgtttt tgattttact
1501 gtgagttaaa aaggcacatt tctaccttct attgttttta aattcaagaa tagggaatta
1561 gttcctggtg ttgtttacga gtgtattctc gtgtcaacat acagggattt agacatttaa
1621 ctctctgtgc cttgataaga atatcattta gagtgtagat acttttgcct ttttaaaaaa
1681 gccattattt tatgagactt agtactcaca ctgcaaataa ctagtcagct cagttttaac
1741 tttataggtt tattgagttt cctttgtgtg atccatgtag atgcctcaaa atgtttcttc
1801 ttcttctttt ttttaatctt ataagatatt tttctaagta tttccagaaa catttgagag
1861 tgcccatcat tttcaggtct gcagaaccat agcttccacg cacctgaacg agcacagaat
1921 gaactgacgg tggaagacat tatgagctgt gtccaacgtt ttaaccaaag cgtatcgtac
1981 caacgatctg tgaaaatgca ctggaagctt ctggtcccgg tttcctttgt ggtctatgtg
2041 ggtcttgtcc tcattgtaac tccgtataga tggtataggt attttaatcc tggaagctgt
2101 tgccttatta atgattatct taaaatttcc tccattgggg cagcgtgggc caaattaaaa
2161 caaacaaaac cgcaactcct ccacagaaac acaaacacag ttattccatg aagtttagta
2221 tttggttgac atagtgctct tcaaattcat cccattaccc taaaagtaat aactttgatg
2281 cttgctttaa ctttagtccc atctctgcca ctttgatgct atttgggtta tgatggggca
2341 agatggcaga ggtattgggt ttttttgttt ttttccattc ctctctactt ctgtttccta
2401 gctttttctt tctggagttt aagtacagtg atggttggct tgagtacctt tttaaatcta
2461 gcccagtata aacattagcc tgcttaatat ttagacattt ataggtagaa ttctgagcac
2521 tcaactcatg tttggcattt taaagtaaaa acaagtgtga cttcgaggac caaagaaatt
2581 gtcagctata catttatctt tatgaactca tttatattcc tttttaatga ctcgttgttc
2641 taacatttcc tagaagtgtt cttataaagg tctaatgtat ccacaggctg ttgtcttatt
2701 agtaaatgca aagtaatgac tttgtctgtt ttactctagt ctttagtact tcaaaattac
2761 cttttcatat ccatgatctt gagtccattt gggggatttt taagaatttg atgtatttca
2821 atacactgtt caaaattaaa ttgtttaatt ttatgtatga gtatgtatgt tcctgaagtt
2881 ggtcctattt aaattattaa actattgtaa ctttgttctt gtgaaaaaaa aaaaaaaaaa
2941 a
＜110〉Attached Tongji Hospital, Tongji Univ.
＜120〉pulmonary thromboembolism related gene and application thereof
<160>142
<210>53
<211>2427
<212>DNA
＜213〉human (Homo sapiens)
<400>53
1 gagagaagga cggagtcgag tggcacccta gaagacgctc tgtgccttcg gaggtctttc
61 tgcctgcctg tcctcatgcc tctcctcctc ttgctgctcc tgctgccaag ccccttacac
121 ccccacccca tctgtgaggt ctccaaagtg gccagccacc tagaagtgaa ctgtgacaag
181 aggaatctga cagcgctgcc tccagacctg ccgaaagaca caaccatcct ccacctgagt
241 gagaacctcc tgtacacctt ctccctggca accctgatgc cttacactcg cctcactcag
301 ctgaacctag ataggtgcga gctcaccaag ctccaggtcg atgggacgct gccagtgctg
361 gggaccctgg atctatccca caatcagctg caaagcctgc ccttgctagg gcagacactg
421 cctgctctca ccgtcctgga cgtctccttc aaccggctga cctcgctgcc tcttggtgcc
481 ctgcgtggtc ttggcgaact ccaagagctc tacctgaaag gcaatgagct gaagaccctg
541 cccccagggc tcctgacgcc cacacccaag ctggagaagc tcagtctggc taacaacaac
601 ttgactgagc tccccgctgg gctcctgaat gggctggaga atctcgacac ccttctcctc
661 caagagaact cgctgtatac aataccaaag ggcttttttg ggtcccacct cctgcctttt
721 gcttttctcc acgggaaccc ctggttatgc aactgtgaga tcctctattt tcgtcgctgg
781 ctgcaggaca atgctgaaaa tgtctacgta tggaagcaag gtgtggacgt caaggccatg
841 acctctaacg tggccagtgt gcagtgtgac aattcagaca agtttcccgt ctacaaatac
901 ccaggaaagg ggtgccccac ccttggtgat gaaggtgaca cagacctata tgattactac
961 ccagaagagg acactgaggg cgataaggtg cgtgccacaa ggactgtggt caagttcccc
1021 accaaagccc atacaacccc ctggggtcta ttctactcat ggtccactgc ttctctagac
1081 agccaaatgc cctcctcctt gcatccaaca caagaatcca ctaaggagca gaccacattc
1141 ccacctagat ggaccccaaa tttcacactt cacatggaat ccatcacatt ctccaaaact
1201 ccaaaatcca ctactgaacc aaccccaagc ccgaccacct cagagcccgt cccggagccc
1261 gccccaaaca tgaccaccct ggagcccact ccaagcccga ccaccccaga gcccacctca
1321 gagcccgccc ccagcccgac caccccggag cccaccccaa tcccgaccat cgccacaagc
1381 ccgaccatcc tggtgtctgc cacaagcctg atcactccaa aaagcacatt tttaactacc
1441 acaaaacccg tatcactctt agaatccacc aaaaaaacca tccctgaact tgatcagcca
1501 ccaaagctcc gtggggtgct ccaagggcat ttggagagct ccagaaatga cccttttctc
1561 caccccgact tttgctgcct cctccccctg ggcttctatg tcttgggtct cttctggctg
1621 ctctttgcct ctgtggtcct catcctgctg ctgagctggg ttgggcatgt gaaaccacag
1681 gccctggact ctggccaagg tgctgctctg accacagcca cacaaaccac acacctggag
1741 ctgcagaggg gacggcaagt gacagtgccc cgggcctggc tgctcttcct tcgaggttcg
1801 cttcccactt tccgctccag cctcttcctg tgggtacggc ctaatggccg tgtggggcct
1861 ctagtggcag gaaggaggcc ctcagctctg agtcagggtc gtggtcagga cctgctgagc
1921 acagtgagca ttaggtactc tggccacagc ctctgagggt gggaggtttg gggaccttga
1981 gagaagagcc tgtgggctct cctattggaa tctagttggg ggttggaggg gtaaggaaca
2041 cagggtgata ggggaggggt cttagttcct ttttctgtat cagaagccct gtcttcacaa
2101 cacaggcaca caatttcagt cccagccaaa gcagaagggg taatgacatg gacttggcgg
2161 ggggacaaga caaagctccc gatgctgcat ggggcgctgc cagatctcac ggtgaaccat
2221 tttggcagaa tacagcatgg ttcccacatg catctatgca cagaagaaaa tctggaaagt
2281 gatttatcag gatgtgagca ctcgttgtgt ctggatgtta caaatatggg tggttttatt
2341 ttctttttcc ctgtttagca ttttctagtt ttccactatt attgtatatt atctgtataa
2401 taaaaaataa ttttagggtt gggaaaa
＜110〉Attached Tongji Hospital, Tongji Univ.
＜120〉pulmonary thromboembolism related gene and application thereof
<160>142
<210>54
<211>2075
<212>DNA
＜213〉human (Homo sapiens)
<400>54
1 gccataaagg ccgccgcgcg cccacgcgcc tcgcttgctg cgcgctgccg gcgctccttc
61 ctcctcggct cgcgtctcac tcagtgtacc ttctagtccc gccatggccg ctctcacccg
121 ggacccccag ttccagaagc tgcagcaatg gtaccgcgag caccgctccg agctgaacct
181 gcgccgcctc ttcgatgcca acaaggaccg cttcaaccac ttcagcttga ccctcaacac
241 caaccatggg catatcctgg tggattactc caagaacctg gtgacggagg acgtgatgcg
301 gatgctggtg gacttggcca agtccagggg cgtggaggcc gcccgggagc ggatgttcaa
361 tggtgagaag atcaactaca ccgagggtcg agccgtgctg cacgtggctc tgcggaaccg
421 gtcaaacaca cccatcctgg tagacggcaa ggatgtgatg ccagaggtca acaaggttct
481 ggacaagatg aagtctttct gccagcgtgt ccggagcggt gactggaagg ggtacacagg
541 caagaccatc acggacgtca tcaacattgg cattggcggc tccgacctgg gacccctcat
601 ggtgactgaa gcccttaagc catactcttc aggaggtccc cgcgtctggt atgtctccaa
661 cattgatgga actcacattg ccaaaaccct ggcccagctg aaccccgagt cctccctgtt
721 catcattgcc tccaagacct ttactaccca ggagaccatc acgaatgcag agacggcgaa
781 ggagtggttt ctccaggcgg ccaaggatcc ttctgcagtg gcgaagcact ttgttgccct
841 gtctactaac acaaccaaag tgaaggagtt tggaattgac cctcaaaaca tgttcgagtt
901 ctgggattgg gtgggaggac gctactcgct gtggtcggcc atcggactct ccattgccct
961 gcacgtgggt tttgacaact tcgagcagct gctctcgggg gctcactgga tggaccagca
1021 cttccgcacg acgcccctgg agaagaacgc ccccgtcttg ctggccctgc tgggtatctg
1081 gtacatcaac tgctttgggt gtgagacaca cgccatgctg ccctatgacc agtacctgca
1141 ccgctttgct gcgtacttcc agcagggcga catggagtcc aatgggaaat acatcaccaa
1201 atctggaacc cgtgtggacc accagacagg ccccattgtg tggggggagc cagggaccaa
1261 tggccagcat gctttttacc agctcatcca ccaaggcacc aagatgatac cctgtgactt
1321 cctcatcccg gtccagaccc agcaccccat acggaagggt ctgcatcaca agatcctcct
1381 ggccaacttc ttggcccaga cagaggccct gatgagggga aaatcgacgg aggaggcccg
1441 aaaggagctc caggctgcgg gcaagagtcc agaggacctt gagaggctgc tgccacataa
1501 ggtctttgaa ggaaatcgcc caaccaactc tattgtgttc accaagctca caccattcat
1561 gcttggagcc ttggtcgcca tgtatgagca caagatcttc gttcagggca tcatctggga
1621 catcaacagc tttgaccagt ggggagtgga gctgggaaag cagctggcta agaaaataga
1681 gcctgagctt gatggcagtg ctcaagtgac ctctcacgac gcttctacca atgggctcat
1741 caacttcatc aagcagcagc gcgaggccag agtccaataa actcgtgctc atctgcagcc
1801 tcctctgtga ctcccctttc tcttctcgtc cctcctcccc ggagccggca ctgcatgttc
1861 ctggacacca cccagagcac cctctggttg tgggcttgga ccacgagccc ttagcaggga
1921 aggctggtct cccccagcct aacccccagc ccctccatgt ctatgctccc tctgtgttag
1981 aattggctga agtgtttttg tgcagctgac ttttctgacc catgttcacg ttgttcacat
2041 cccatgtaga aaaataaaga tgccacggag gaggt
＜110〉Attached Tongji Hospital, Tongji Univ.
＜120〉pulmonary thromboembolism related gene and application thereof
<160>142
<210>55
<211>2237
<212>DNA
＜213〉human (Homo sapiens)
<400>55
1 atgaccttgg ctgctttcat ctctgaagcg ccacttctca gaaacacaga gctttagctc
61 cgccaaaatg aaacactcat taaacgcact tctcattttc ctcatcataa catctgcgtg
121 gggtgggagc aaaggcccgc tggatcagct agagaaagga ggggaaactg ctcagtctgc
181 agatccccag tgggagcagt taaataacaa aaacctgagc atgcctcttc tccctgccga
241 cttccacaag gaaaacaccg tcaccaacga ctggattcca gagggggagg aggacgacga
301 ctatctggac ctggagaaga tattcagtga agacgacgac tacatcgaca tcgtcgacag
361 tctgtcagtt tccccgacag actctgatgt gagtgctggg aacatcctcc agctttttca
421 tggcaagagc cggatccagc gtcttaacat cctcaacgcc aagttcgctt tcaacctcta
481 ccgagtgctg aaagaccagg tcaacacttt cgataacatc ttcatagcac ccgttggcat
541 ttctactgcg atgggtatga tttccttagg tctgaaggga gagacccatg aacaagtgca
601 ctcgattttg cattttaaag actttgttaa tgccagcagc aagtatgaaa tcacgaccat
661 tcataatctc ttccgtaagc tgactcatcg cctcttcagg aggaattttg ggtacacact
721 gcggtcagtc aatgaccttt atatccagaa gcagtttcca atcctgcttg acttcaaaac
781 taaagtaaga gagtattact ttgctgaggc ccagatagct gacttctcag accctgcctt
841 catatcaaaa accaacaacc acatcatgaa gctcaccaag ggcctcataa aagatgctct
901 ggagaatata gaccctgcta cccagatgat gattctcaac tgcatctact tcaaaggatc
961 ctgggtgaat aaattcccag tggaaatgac acacaaccac aacttccggc tgaatgagag
1021 agaggtagtt aaggtttcca tgatgcagac caaggggaac ttcctcgcag caaatgacca
1081 ggagctggac tgcgacatcc tccagctgga atacgtgggg ggcatcagca tgctaattgt
1141 ggtcccacac aagatgtctg ggatgaagac cctcgaagcg caactgacac cccgggtggt
1201 ggagagatgg caaaaaagca tgacaaacag aactcgagaa gtgcttctgc cgaaattcaa
1261 gctggagaag aactacaatc tagtggagtc cctgaagttg atggggatca ggatgctgtt
1321 tgacaaaaat ggcaacatgg caggcatctc agaccaaagg atcgccatcg acctgttcaa
1381 gcaccaaggc acgatcacag tgaacgagga aggcacccaa gccaccactg tgaccacggt
1441 ggggttcatg ccgctgtcca cccaagtccg cttcactgtc gaccgcccct ttcttttcct
1501 catctacgag catcgcacca gctgcctgct cttcatggga agagtggcca accccagcag
1561 gtcctagagg tggaggtcta ggtgtctgaa gtgccttggg ggcaccctca ttttgtttcc
1621 attccaacaa cgagaacaga gatgttctgg catcatttac gtagtttacg ctaccaatct
1681 gaattcgagg cccatatgag aggagcttag aaacgaccaa gaagagaggc ttgttggaat
1741 caattctgca caatagccca tgctgtaagc tcatagaagt cactgtaact gtagtgtgtc
1801 tgctgttacc tagagggtct cacctcccca ctcttcacag caaacctgag cagcgcgtcc
1861 taagcacctc ccgctccggt gaccccatcc ttgcacacct gactctgtca ctcaagcctt
1921 tctccaccag gcccctcatc tgaataccaa gcacagaaat gagtggtgtg actaattcct
1981 tacctctccc aaggagggta cacaactagc accattcttg atgtccaggg aagaagccac
2041 ctcaagacat atgaggggtg ccctgggcta atgttagggc ttaattttct caaagcctga
2101 cctttcaaat ccatgatgaa tgccatcagt ccctcctgct gttgcctccc tgtgacctgg
2161 aggacagtgt gtgccatgtc tcccatacta gagataaata aatgtagcca catttactgt
2221 gaaaaaaaaa aaaaaaa
＜110〉Attached Tongji Hospital, Tongji Univ.
＜120〉pulmonary thromboembolism related gene and application thereof
<160>142
<210>56
<211>4894
<212>DNA
＜213〉human (Homo sapiens)
<400>56
1 cgccgcggga ggcggacgag atgcgagcgc ggccgcggcc ccggccgctc tgggcgactg
61 tgctggcgct gggggcgctg gcgggcgttg gcgtaggagg gcccaacatc tgtaccacgc
121 gaggtgtgag ctcctgccag cagtgcctgg ctgtgagccc catgtgtgcc tggtgctctg
181 atgaggccct gcctctgggc tcacctcgct gtgacctgaa ggagaatctg ctgaaggata
241 actgtgcccc agaatccatc gagttcccag tgagtgaggc ccgagtacta gaggacaggc
301 ccctcagcga caagggctct ggagacagct cccaggtcac tcaagtcagt ccccagagga
361 ttgcactccg gctccggcca gatgattcga agaatttctc catccaagtg cggcaggtgg
421 aggattaccc tgtggacatc tactacttga tggacctgtc ttactccatg aaggatgatc
481 tgtggagcat ccagaacctg ggtaccaagc tggccaccca gatgcgaaag ctcaccagta
541 acctgcggat tggcttcggg gcatttgtgg acaagcctgt gtcaccatac atgtatatct
601 ccccaccaga ggccctcgaa aacccctgct atgatatgaa gaccacctgc ttgcccatgt
661 ttggctacaa acacgtgctg acgctaactg accaggtgac ccgcttcaat gaggaagtga
721 agaagcagag tgtgtcacgg aaccgagatg ccccagaggg tggctttgat gccatcatgc
781 aggctacagt ctgtgatgaa aagattggct ggaggaatga tgcatcccac ttgctggtgt
841 ttaccactga tgccaagact catatagcat tggacggaag gctggcaggc attgtccagc
901 ctaatgacgg gcagtgtcat gttggtagtg acaatcatta ctctgcctcc actaccatgg
961 attatccctc tttggggctg atgactgaga agctatccca gaaaaacatc aatttgatct
1021 ttgcagtgac tgaaaatgta gtcaatctct atcagaacta tagtgagctc atcccaggga
1081 ccacagttgg ggttctgtcc atggattcca gcaatgtcct ccagctcatt gttgatgctt
1141 atgggaaaat ccgttctaaa gtagagctgg aagtgcgtga cctccctgaa gagttgtctc
1201 tatccttcaa tgccacctgc ctcaacaatg aggtcatccc tggcctcaag tcttgtatgg
1261 gactcaagat tggagacacg gtgagcttca gcattgaggc caaggtgcga ggctgtcccc
1321 aggagaagga gaagtccttt accataaagc ccgtgggctt caaggacagc ctgatcgtcc
1381 aggtcacctt tgattgtgac tgtgcctgcc aggcccaagc tgaacctaat agccatcgct
1441 gcaacaatgg caatgggacc tttgagtgtg gggtatgccg ttgtgggcct ggctggctgg
1501 gatcccagtg tgagtgctca gaggaggact atcgcccttc ccagcaggac gaatgcagcc
1561 cccgggaggg tcagcccgtc tgcagccagc ggggcgagtg cctctgtggt caatgtgtct
1621 gccacagcag tgactttggc aagatcacgg gcaagtactg cgagtgtgac gacttctcct
1681 gtgtccgcta caagggggag atgtgctcag gccatggcca gtgcagctgt ggggactgcc
1741 tgtgtgactc cgactggacc ggctactact gcaactgtac cacgcgtact gacacctgca
1801 tgtccagcaa tgggctgctg tgcagcggcc gcggcaagtg tgaatgtggc agctgtgtct
1861 gtatccagcc gggctcctat ggggacacct gtgagaagtg ccccacctgc ccagatgcct
1921 gcacctttaa gaaagaatgt gtggagtgta agaagtttga ccggggagcc ctacatgacg
1981 aaaatacctg caaccgttac tgccgtgacg agattgagtc agtgaaagag cttaaggaca
2041 ctggcaagga tgcagtgaat tgtacctata agaatgagga tgactgtgtc gtcagattcc
2101 agtactatga agattctagt ggaaagtcca tcctgtatgt ggtagaagag ccagagtgtc
2161 ccaagggccc tgacatcctg gtggtcctgc tctcagtgat gggggccatt ctgctcattg
2221 gccttgccgc cctgctcatc tggaaactcc tcatcaccat ccacgaccga aaagaattcg
2281 ctaaatttga ggaagaacgc gccagagcaa aatgggacac agccaacaac ccactgtata
2341 aagaggccac gtctaccttc accaatatca cgtaccgggg cacttaatga taagcagtca
2401 tcctcagatc attatcagcc tgtgccacga ttgcaggagt ccctgccatc atgtttacag
2461 aggacagtat ttgtggggag ggatttgggg ctcagagtgg ggtaggttgg gagaatgtca
2521 gtatgtggaa gtgtgggtct gtgtgtgtgt atgtgggggt ctgtgtgttt atgtgtgtgt
2581 gttgtgtgtg ggagtgtgta atttaaaatt gtgatgtgtc ctgataagct gagctcctta
2641 gcctttgtcc cagaatgcct cctgcaggga ttcttcctgc ttagcttgag ggtgactatg
2701 gagctgagca ggtgttcttc attacctcag tgagaagcca gctttcctca tcaggccatt
2761 gtccctgaag agaagggcag ggctgaggcc tctcattcca gaggaaggga caccaagcct
2821 tggctctacc ctgagttcat aaatttatgg ttctcaggcc tgactctcag cagctatggt
2881 aggaactgct gggcttggca gcccgggtca tctgtacctc tgcctccttt cccctccctc
2941 aggccgaagg aggagtcagg gagagctgaa ctattagagc tgcctgtgcc ttttgccatc
3001 ccctcaaccc agctatggtt ctctcgcaag ggaagtcctt gcaagctaat tctttgacct
3061 gttgggagtg aggatgtctg ggccactcag gggtcattca tggcctgggg gatgtaccag
3121 catctcccag ttcataatca caacccttca gatttgcctt attggcagct ctactctgga
3181 ggtttgttta gaagaagtgt gtcaccctta ggccagcacc atctctttac ctcctaattc
3241 cacaccctca ctgctgtaga catttgctat gagctgggga tgtctctcat gaccaaatgc
3301 ttttcctcaa agggagagag tgctattgta gagccagagg tctggcccta tgcttccggc
3361 ctcctgtccc tcatccatag cacctccaca tacctggccc tgtgccttgg tgtgctgtat
3421 ccatccatgg ggctgattgt atttaccttc tacctcttgg ctgccttgtg aaggaattat
3481 tcccatgagt tggctgggaa taagtgccag gatggaatga tgggtcagtt gtatcagcac
3541 gtgtggcctg ttcttctatg ggttggacaa cctcatttta actcagtctt taatctgaga
3601 ggccacagtg caattttatt ttatttttct catgatgagg ttttcttaac ttaaaagaac
3661 atgtatataa acatgcttgc attatatttg taaatttatg tgatggcaaa gaaggagagc
3721 ataggaaacc acacagactt gggcagggta cagacactcc cacttggcat cattcacagc
3781 aagtcactgg ccagtggctg gatctgtgag gggctctctc atgatagaag gctatgggga
3841 tagatgtgtg gacacattgg acctttcctg aggaagaggg actgttcttt tgtcccagaa
3901 aagcagtggc tccattggtg ttgacataca tccaacatta aaagccaccc ccaaatgccc
3961 aagaaaaaaa gaaagactta tcaacatttg ttccatgagc agaaaactgg agctctggcc
4021 tcagtgttac agctaaataa tctttaatta aggcaagtca ctttcttctt cttaaagctg
4081 ttttctagtt tgagaaatga tgggatttta gcagccagtc ttgaaggtct ctttcagtat
4141 caacattcta agatgctggg acttactgtg tcatcaaatg tgcggttaag attctctggg
4201 atattgatac tgtttgtgtt tttagttggg agatctgaga gacctggctt tggcaagagc
4261 agatgtcatt ccatatcacc tttctcaatg aaagtctcat tctatcctct ctccaaaccc
4321 gttttccaac atttgttaat agttacgtct ctcctgatgt agcacttaag cttcatttag
4381 ttattatttc tttcttcact ttgcacacat ttgcatccac atattaggga agaggaatcc
4441 ataagtagct gaaatatcta ttctgtatta ttgtgttaac attgagaata agccttggaa
4501 ttagatatgg ggcaatgact gagccctgtc tcacccatgg attactcctt actgtaggga
4561 atggcagtat ggtagaggga taaatagggg gcggggaggg atagtcatgg atccaagaag
4621 tccttagaaa tagtggcagg gaacaggtgt ggaagctcat gcctgtaatt ataaccttca
4681 gctactaaga caggtgtggt ggctcacgcc tgtgattata atcttcagtt actaagacag
4741 agtccatgag agtgttaatg ggacattttc tttagataag atgttttata tgaagaaact
4801 gtatcaaagg gggaagaaaa tgtatttaac aggtgaatca aatcaggaat cttgtctgag
4861 ctactggaat gaagttcaca ggtcttgaag acca
＜110〉Attached Tongji Hospital, Tongji Univ.
＜120〉pulmonary thromboembolism related gene and application thereof
<160>142
<210>57
<211>5896
<212>DNA
＜213〉human (Homo sapiens)
<400>57
1 ctgcggccgg cccgcgagct aggctgggtt tttttttttc tcccctccct cccccctttt
61 tccatgcagc tgatctaaaa gggaataaaa ggctgcgcat aatcataata ataaaagaag
121 gggagcgcga gagaaggaaa gaaagccggg aggtggaaga ggagggggag cgtctcaaag
181 aagcgatcag aataataaaa ggaggccggg ctctttgcct tctggaacgg gccgctcttg
241 aaagggcttt tgaaaagtgg tgttgttttc cagtcgtgca tgctccaatc ggcggagtat
301 attagagccg ggacgcggcg gccgcagggg cagcggcgac ggcagcaccg gcggcagcac
361 cagcgcgaac agcagcggcg gcgtcccgag tgcccgcggc gcgcggcgca gcgatgcgtt
421 ccccacggac gcgcggccgg tccgggcgcc ccctaagcct cctgctcgcc ctgctctgtg
481 ccctgcgagc caaggtgtgt ggggcctcgg gtcagttcga gttggagatc ctgtccatgc
541 agaacgtgaa cggggagctg cagaacggga actgctgcgg cggcgcccgg aacccgggag
601 accgcaagtg cacccgcgac gagtgtgaca catacttcaa agtgtgcctc aaggagtatc
661 agtcccgcgt cacggccggg gggccctgca gcttcggctc agggtccacg cctgtcatcg
721 ggggcaacac cttcaacctc aaggccagcc gcggcaacga ccgcaaccgc atcgtgctgc
781 ctttcagttt cgcctggccg aggtcctata cgttgcttgt ggaggcgtgg gattccagta
841 atgacaccgt tcaacctgac agtattattg aaaaggcttc tcactcgggc atgatcaacc
901 ccagccggca gtggcagacg ctgaagcaga acacgggcgt tgcccacttt gagtatcaga
961 tccgcgtgac ctgtgatgac tactactatg gctttggctg caataagttc tgccgcccca
1021 gagatgactt ctttggacac tatgcctgtg accagaatgg caacaaaact tgcatggaag
1081 gctggatggg ccccgaatgt aacagagcta tttgccgaca aggctgcagt cctaagcatg
1141 ggtcttgcaa actcccaggt gactgcaggt gccagtatgg ctggcaaggc ctgtactgtg
1201 ataagtgcat cccacacccg ggatgcgtcc acggcatctg taatgagccc tggcagtgcc
1261 tctgtgagac caactggggc ggccagctct gtgacaaaga tctcaattac tgtgggactc
1321 atcagccgtg tctcaacggg ggaacttgta gcaacacagg ccctgacaaa tatcagtgtt
1381 cctgccctga ggggtattca ggacccaact gtgaaattgc tgagcacgcc tgcctctctg
1441 atccctgtca caacagaggc agctgtaagg agacctccct gggctttgag tgtgagtgtt
1501 ccccaggctg gaccggcccc acatgctcta caaacattga tgactgttct cctaataact
1561 gttcccacgg gggcacctgc caggacctgg ttaacggatt taagtgtgtg tgccccccac
1621 agtggactgg gaaaacgtgc cagttagatg caaatgaatg tgaggccaaa ccttgtgtaa
1681 acgccaaatc ctgtaagaat ctcattgcca gctactactg cgactgtctt cccggctgga
1741 tgggtcagaa ttgtgacata aatattaatg actgccttgg ccagtgtcag aatgacgcct
1801 cctgtcggga tttggttaat ggttatcgct gtatctgtcc acctggctat gcaggcgatc
1861 actgtgagag agacatcgat gaatgtgcca gcaacccctg tttgaatggg ggtcactgtc
1921 agaatgaaat caacagattc cagtgtctgt gtcccactgg tttctctgga aacctctgtc
1981 agctggacat cgattattgt gagcctaatc cctgccagaa cggtgcccag tgctacaacc
2041 gtgccagtga ctatttctgc aagtgccccg aggactatga gggcaagaac tgctcacacc
2101 tgaaagacca ctgccgcacg accccctgtg aagtgattga cagctgcaca gtggccatgg
2161 cttccaacga cacacctgaa ggggtgcggt atatttcctc caacgtctgt ggtcctcacg
2221 ggaagtgcaa gagtcagtcg ggaggcaaat tcacctgtga ctgtaacaaa ggcttcacgg
2281 gaacatactg ccatgaaaat attaatgact gtgagagcaa cccttgtaga aacggtggca
2341 cttgcatcga tggtgtcaac tcctacaagt gcatctgtag tgacggctgg gagggggcct
2401 actgtgaaac caatattaat gactgcagcc agaacccctg ccacaatggg ggcacgtgtc
2461 gcgacctggt caatgacttc tactgtgact gtaaaaatgg gtggaaagga aagacctgcc
2521 actcacgtga cagtcagtgt gatgaggcca cgtgcaacaa cggtggcacc tgctatgatg
2581 agggggatgc ttttaagtgc atgtgtcctg gcggctggga aggaacaacc tgtaacatag
2641 cccgaaacag tagctgcctg cccaacccct gccataatgg gggcacatgt gtggtcaacg
2701 gcgagtcctt tacgtgcgtc tgcaaggaag gctgggaggg gcccatctgt gctcagaata
2761 ccaatgactg cagccctcat ccctgttaca acagcggcac ctgtgtggat ggagacaact
2821 ggtaccggtg cgaatgtgcc ccgggttttg ctgggcccga ctgcagaata aacatcaatg
2881 aatgccagtc ttcaccttgt gcctttggag cgacctgtgt ggatgagatc aatggctacc
2941 ggtgtgtctg ccctccaggg cacagtggtg ccaagtgcca ggaagtttca gggagacctt
3001 gcatcaccat ggggagtgtg ataccagatg gggccaaatg ggatgatgac tgtaatacct
3061 gccagtgcct gaatggacgg atcgcctgct caaaggtctg gtgtggccct cgaccttgcc
3121 tgctccacaa agggcacagc gagtgcccca gcgggcagag ctgcatcccc atcctggacg
3181 accagtgctt cgtccacccc tgcactggtg tgggcgagtg tcggtcttcc agtctccagc
3241 cggtgaagac aaagtgcacc tctgactcct attaccagga taactgtgcg aacatcacat
3301 ttacctttaa caaggagatg atgtcaccag gtcttactac ggagcacatt tgcagtgaat
3361 tgaggaattt gaatattttg aagaatgttt ccgctgaata ttcaatctac atcgcttgcg
3421 agccttcccc ttcagcgaac aatgaaatac atgtggccat ttctgctgaa gatatacggg
3481 atgatgggaa cccgatcaag gaaatcactg acaaaataat cgatcttgtt agtaaacgtg
3541 atggaaacag ctcgctgatt gctgccgttg cagaagtaag agttcagagg cggcctctga
3601 agaacagaac agatttcctt gttcccttgc tgagctctgt cttaactgtg gcttggatct
3661 gttgcttggt gacggccttc tactggtgcc tgcggaagcg gcggaagccg ggcagccaca
3721 cacactcagc ctctgaggac aacaccacca acaacgtgcg ggagcagctg aaccagatca
3781 aaaaccccat tgagaaacat ggggccaaca cggtccccat caaggattac gagaacaaga
3841 actccaaaat gtctaaaata aggacacaca attctgaagt agaagaggac gacatggaca
3901 aacaccagca gaaagcccgg tttgccaagc agccggcgta tacgctggta gacagagaag
3961 agaagccccc caacggcacg ccgacaaaac acccaaactg gacaaacaaa caggacaaca
4021 gagacttgga aagtgcccag agcttaaacc gaatggagta catcgtatag cagaccgcgg
4081 gcactgccgc cgctaggtag agtctgaggg cttgtagttc tttaaactgt cgtgtcatac
4141 tcgagtctga ggccgttgct gacttagaat ccctgtgtta atttaagttt tgacaagctg
4201 gcttacactg gcaatggtag tttctgtggt tggctgggaa atcgagtgcc gcatctcaca
4261 gctatgcaaa aagctagtca acagtaccct ggttgtgtgt ccccttgcag ccgacacggt
4321 ctcggatcag gctcccagga gcctgcccag ccccctggtc tttgagctcc cacttctgcc
4381 agatgtccta atggtgatgc agtcttagat catagtttta tttatattta ttgactcttg
4441 agttgttttt gtatattggt tttatgatga cgtacaagta gttctgtatt tgaaagtgcc
4501 tttgcagctc agaaccacag caacgatcac aaatgacttt attatttatt tttttaattg
4561 tatttttgtt gttgggggag gggagacttt gatgtcagca gttgctggta aaatgaagaa
4621 tttaaagaaa aaaatgtcaa aagtagaact ttgtatagtt atgtaaataa ttctttttta
4681 ttaatcactg tgtatatttg atttattaac ttaataatca agagccttaa aacatcattc
4741 ctttttattt atatgtatgt gtttagaatt gaaggttttt gatagcattg taagcgtatg
4801 gctttatttt tttgaactct tctcattact tgttgcctat aagccaaaat taaggtgttt
4861 gaaaatagtt tattttaaaa caataggatg ggcttctgtg cccagaatac tgatggaatt
4921 ttttttgtac gacgtcagat gtttaaaaca ccttctatag catcacttaa aacacgtttt
4981 aaggactgac tgaggcagtt tgaggattag tttagaacag gtttttttgt ttgtttgttt
5041 tttgtttttc tgctttagac ttgaaaagag acaggcaggt gatctgctgc agagcagtaa
5101 gggaacaagt tgagctatga cttaacatag ccaaaatgtg agtggttgaa tatgattaaa
5161 aatatcaaat taattgtgtg aacttggaag cacaccaatc tgactttgta aattctgatt
5221 tcttttcacc attcgtacat aatactgaac cacttgtaga tttgattttt tttttaatct
5281 actgcattta gggagtattc taataagcta gttgaatact tgaaccataa aatgtccagt
5341 aagatcactg tttagatttg ccatagagta cactgcctgc cttaagtgag gaaatcaaag
5401 tgctattacg aagttcaaga tcaaaaaggc ttataaaaca gagtaatctt gttggttcac
5461 cattgagacc gtgaagatac tttgtattgt cctattagtg ttatatgaac atacaaatgc
5521 atctttgatg tgttgttctt ggcaataaat tttgaaaagt aatatttatt aaattttttt
5581 gtatgaaaac atggaacagt gtggctcttc tgagcttacg tagttctacc ggctttgccg
5641 tgtgcttctg ccaccctgct gagtctgttc tggtaatcgg ggtataatag gctctgcctg
5701 acagagggat ggaggaagaa ctgaaaggct tttcaaccac aaaactcatc tggagttctc
5761 aaagacctgg ggctgctgtg aagctggaac tgcgggagcc ccatctaggg gagccttgat
5821 tcccttgtta ttcaacagca agtgtgaata ctgcttgaat aaacaccact ggattaatgg
5881 aaaaaaaaaa aaaaaa
＜110〉Attached Tongji Hospital, Tongji Univ.
＜120〉pulmonary thromboembolism related gene and application thereof
<160>142
<210>58
<211>2732
<212>DNA
＜213〉human (Homo sapiens)
<400>58
1 aacaacatcc tgggattggg acccactttc tgggcactgc tggccagtcc caaaatggaa
61 cataaggaag tggttcttct acttctttta tttctgaaat caggtcaagg agagcctctg
121 gatgactatg tgaataccca gggggcttca ctgttcagtg tcactaagaa gcagctggga
181 gcaggaagta tagaagaatg tgcagcaaaa tgtgaggagg acgaagaatt cacctgcagg
241 gcattccaat atcacagtaa agagcaacaa tgtgtgataa tggctgaaaa caggaagtcc
301 tccataatca ttaggatgag agatgtagtt ttatttgaaa agaaagtgta tctctcagag
361 tgcaagactg ggaatggaaa gaactacaga gggacgatgt ccaaaacaaa aaatggcatc
421 acctgtcaaa aatggagttc cacttctccc cacagaccta gattctcacc tgctacacac
481 ccctcagagg gactggagga gaactactgc aggaatccag acaacgatcc gcaggggccc
541 tggtgctata ctactgatcc agaaaagaga tatgactact gcgacattct tgagtgtgaa
601 gaggaatgta tgcattgcag tggagaaaac tatgacggca aaatttccaa gactatgtct
661 ggactggaat gccaggcctg ggactctcag agcccacacg ctcatggata cattccttcc
721 aaatttccaa acaagaacct gaagaagaat tactgtcgta accccgatag ggagctgcgg
781 ccttggtgtt tcaccaccga ccccaacaag cgctgggaac tttgcgacat cccccgctgc
841 acaacacctc caccatcttc tggtcccacc taccagtgtc tgaagggaac aggtgaaaac
901 tatcgcggga atgtggctgt taccgtttcc gggcacacct gtcagcactg gagtgcacag
961 acccctcaca cacataacag gacaccagaa aacttcccct gcaaaaattt ggatgaaaac
1021 tactgccgca atcctgacgg aaaaagggcc ccatggtgcc atacaaccaa cagccaagtg
1081 cggtgggagt actgtaagat accgtcctgt gactcctccc cagtatccac ggaacaattg
1141 gctcccacag caccacctga gctaacccct gtggtccagg actgctacca tggtgatgga
1201 cagagctacc gaggcacatc ctccaccacc accacaggaa agaagtgtca gtcttggtca
1261 tctatgacac cacaccggca ccagaagacc ccagaaaact acccaaatgc tggcctgaca
1321 atgaactact gcaggaatcc agatgccgat aaaggcccct ggtgttttac cacagacccc
1381 agcgtcaggt gggagtactg caacctgaaa aaatgctcag gaacagaagc gagtgttgta
1441 gcacctccgc ctgttgtcct gcttccagat gtagagactc cttccgaaga agactgtatg
1501 tttgggaatg ggaaaggata ccgaggcaag agggcgacca ctgttactgg gacgccatgc
1561 caggactggg ctgcccagga gccccataga cacagcattt tcactccaga gacaaatcca
1621 cgggcgggtc tggaaaaaaa ttactgccgt aaccctgatg gtgatgtagg tggtccctgg
1681 tgctacacga caaatccaag aaaactttac gactactgtg atgtccctca gtgtgcggcc
1741 ccttcatttg attgtgggaa gcctcaagtg gagccgaaga aatgtcctgg aagggttgtg
1801 ggggggtgtg tggcccaccc acattcctgg ccctggcaag tcagtcttag aacaaggttt
1861 ggaatgcact tctgtggagg caccttgata tccccagagt gggtgttgac tgctgcccac
1921 tgcttggaga agtccccaag gccttcatcc tacaaggtca tcctgggtgc acaccaagaa
1981 gtgaatctcg aaccgcatgt tcaggaaata gaagtgtcta ggctgttctt ggagcccaca
2041 cgaaaagata ttgccttgct aaagctaagc agtcctgccg tcatcactga caaagtaatc
2101 ccagcttgtc tgccatcccc aaattatgtg gtcgctgacc ggaccgaatg tttcatcact
2161 ggctggggag aaacccaagg tacttttgga gctggccttc tcaaggaagc ccagctccct
2221 gtgattgaga ataaagtgtg caatcgctat gagtttctga atggaagagt ccaatccacc
2281 gaactctgtg ctgggcattt ggccggaggc actgacagtt gccagggtga cagtggaggt
2341 cctctggttt gcttcgagaa ggacaaatac attttacaag gagtcacttc ttggggtctt
2401 ggctgtgcac gccccaataa gcctggtgtc tatgttcgtg tttcaaggtt tgttacttgg
2461 attgagggag tgatgagaaa taattaattg gacgggagac agagtgacgc actgactcac
2521 ctagaggctg ggacgtgggt agggatttag catgctggaa ataactggca gtaatcaaac
2581 gaagacactg tccccagcta ccagctacgc caaacctcgg cattttttgt gttattttct
2641 gactgctgga ttctgtagta aggtgacata gctatgacat ttgttaaaaa taaactctgt
2701 acttaacttt gatttgagta aattttggtt tt
＜110〉Attached Tongji Hospital, Tongji Univ.
＜120〉pulmonary thromboembolism related gene and application thereof
<160>142
<210>59
<211>1843
<212>DNA
＜213〉human (Homo sapiens)
<400>59
1 ctgcaggggg gggggggggg gggggctgtc atggcggcag gacggcgaac ttgcagtatc
61 tccacgaccc gcccctacag gtgccagtgc ctccagaatg tggcagctca caagcctcct
121 gctgttcgtg gccacctggg gaatttccgg cacaccagct cctcttgact cagtgttctc
181 cagcagcgag cgtgcccacc aggtgctgcg gatccgcaaa cgtgccaact ccttcctgga
241 ggagctccgt cacagcagcc tggagcggga gtgcatagag gagatctgtg acttcgagga
301 ggccaaggaa attttccaaa atgtggatga cacactggcc ttctggtcca agcacgtcga
361 cggtgaccag tgcttggtct tgcccttgga gcacccgtgc gccagcctgt gctgcgggca
421 cggcacgtgc atcgacggca tcggcagctt cagctgcgac tgccgcagcg gctgggaggg
481 ccgcttctgc cagcgcgagg tgagcttcct caattgctcg ctggacaacg gcggctgcac
541 gcattactgc ctagaggagg tgggctggcg gcgctgtagc tgtgcgcctg gctacaagct
601 gggggacgac ctcctgcagt gtcaccccgc agtgaagttc ccttgtggga ggccctggaa
661 gcggatggag aagaagcgca gtcacctgaa acgagacaca gaagaccaag aagaccaagt
721 agatccgcgg ctcattgatg ggaagatgac caggcgggga gacagcccct ggcaggtggt
781 cctgctggac tcaaagaaga agctggcctg cggggcagtg ctcatccacc cctcctgggt
841 gctgacagcg gcccactgca tggatgagtc caagaagctc cttgtcaggc ttggagagta
901 tgacctgcgg cgctgggaga agtgggagct ggacctggac atcaaggagg tcttcgtcca
961 ccccaactac agcaagagca ccaccgacaa tgacatcgca ctgctgcacc tggcccagcc
1021 cgccaccctc tcgcagacca tagtgcccat ctgcctcccg gacagcggcc ttgcagagcg
1081 cgagctcaat caggccggcc aggagaccct cgtgacgggc tggggctacc acagcagccg
1141 agagaaggag gccaagagaa accgcacctt cgtcctcaac ttcatcaaga ttcccgtggt
1201 cccgcacaat gagtgcagcg aggtcatgag caacatggtg tctgagaaca tgctgtgtgc
1261 gggcatcctc ggggaccggc aggatgcctg cgagggcgac agtggggggc ccatggtcgc
1321 ctccttccac ggcacctggt tcctggtggg cctggtgagc tggggtgagg gctgtgggct
1381 ccttcacaac tacggcgttt acaccaaagt cagccgctac ctcgactgga tccatgggca
1441 catcagagac aaggaagccc cccagaagag ctgggcacct tagcgaccct ccctgcaggg
1501 ctgggctttt gcatggcaat ggatgggaca ttaaagggac atgtaacaag cacaccggcc
1561 tgctgttctg tccttccatc cctcttttgg gctcttctgg agggaagtaa catttactga
1621 gcacctgttg tatgtcacat gccttatgaa tagaatctta actcctagag caactctgtg
1681 gggtggggag gagcagatcc aagttttgcg gggtctaaag ctgtgtgtgt tgagggggat
1741 actctgttta tgaaaaagaa taaaaaacac aaccacgaaa aaaaaaaaaa aaaaaaaaaa
1801 aaaaaaaaaa aaaaaaaccc ccccccgccc cccccccctg cag
＜110〉Attached Tongji Hospital, Tongji Univ.
＜120〉pulmonary thromboembolism related gene and application thereof
<160>142
<210>60
<211>3309
<212>DNA
＜213〉human (Homo sapiens)
<400>60
1 ctgcaggggg gggggggggg gggggggggg ggggggggcg cagcacggct cagaccgagg
61 cgcacaggct cgcagctccg ggcgcctagc gcccggtccc cgccgcgacg cgccaccgtc
121 cctgccggcg cctccgcgcc ttcgaaatga gggtcctggg tgggcgctgc ggggcgccgc
181 tggcgtgtct cctcctagtg cttcccgtct cagaggcaaa ccttctgtca aagcaacagg
241 cttcacaagt cctggttagg aagcgtcgtg caaattcttt acttgaagaa accaaacagg
301 gtaatcttga aagagaatgc atcgaagaac tgtgcaataa agaagaagcc agggaggtct
361 ttgaaaatga cccggaaacg gattattttt atccaaaata cttagtttgt cttcgctctt
421 ttcaaactgg gttattcact gctgcacgtc agtcaactaa tgcttatcct gacctaagaa
481 gctgtgtcaa tgccattcca gaccagtgta gtcctctgcc atgcaatgaa gatggatata
541 tgagctgcaa agatggaaaa gcttctttta cttgcacttg taaaccaggt tggcaaggag
601 aaaagtgtga atttgacata aatgaatgca aagatccctc aaatataaat ggaggttgca
661 gtcaaatttg tgataataca cctggaagtt accactgttc ctgtaaaaat ggttttgtta
721 tgctttcaaa taagaaagat tgtaaagatg tggatgaatg ctctttgaag ccaagcattt
781 gtggcacagc tgtgtgcaag aacatcccag gagattttga atgtgaatgc cccgaaggct
841 acagatataa tctcaaatca aagtcttgtg aagatataga tgaatgctct gagaacatgt
901 gtgctcagct ttgtgtcaat taccctggag gttacacttg ctattgtgat gggaagaaag
961 gattcaaact tgcccaagat cagaagagtt gtgaggttgt ttcagtgtgc cttcccttga
1021 accttgacac aaagtatgaa ttactttact tggcggagca gtttgcaggg gttgttttat
1081 atttaaaatt tcgtttgcca gaaatcagca gattttcagc agaatttgat ttccggacat
1141 atgattcaga aggcgtgata ctgtacgcag aatctatcga tcactcagcg tggctcctga
1201 ttgcacttcg tggtggaaag attgaagttc agcttaagaa tgaacataca tccaaaatca
1261 caactggagg tgatgttatt aataatggtc tatggaatat ggtgtctgtg gaagaattag
1321 aacatagtat tagcattaaa atagctaaag aagctgtgat ggatataaat aaacctggac
1381 ccctttttaa gccggaaaat ggattgctgg aaaccaaagt atactttgca ggattccctc
1441 ggaaagtgga aagtgaactc attaaaccga ttaaccctcg tctagatgga tgtatacgaa
1501 gctggaattt gatgaagcaa ggagcttctg gaataaagga aattattcaa gaaaaacaaa
1561 ataagcattg cctggttact gtggagaagg gctcctacta tcctggttct ggaattgctc
1621 aatttcacat agattataat aatgtatcca gtgctgaggg ttggcatgta aatgtgacct
1681 tgaatattcg tccatccacg ggcactggtg ttatgcttgc cttggtttct ggtaacaaca
1741 cagtgccctt tgctgtgtcc ttggtggact ccacctctga aaaatcacag gatattctgt
1801 tatctgttga aaatactgta atatatcgga tacaggccct aagtctatgt tccgatcaac
1861 aatctcatct ggaatttaga gtcaacagaa acaatctgga gttgtcgaca ccacttaaaa
1921 tagaaaccat ctcccatgaa gaccttcaaa gacaacttgc cgtcttggac aaagcaatga
1981 aagcaaaagt ggccacatac ctgggtggcc ttccagatgt tccattcagt gccacaccag
2041 tgaatgcctt ttataatggc tgcatggaag tgaatattaa tggtgtacag ttggatctgg
2101 atgaagccat ttctaaacat aatgatatta gagctcactc atgtccatca gtttggaaaa
2161 agacaaagaa ttcttaaggc atcttttctc tgcttataat accttttcct tgtgtgtaat
2221 tatacttatg tttcaataac agctgaaggg ttttatttac aatgtgcagt ctttgattat
2281 tttgtggtcc tttcctggga tttttaaaag gtcctttgtc aaggaaaaaa attctgttgt
2341 gatataaatc acagtaaaga aattcttact tctcttgcta tctaagaata gtgaaaaata
2401 acaattttaa atttgaattt ttttcctaca aatgacagtt tcaatttttg tttgtaaaac
2461 taaattttaa ttttatcatc atgaactagt gtctaaatac ctatgttttt ttcagaaagc
2521 aaggaagtaa actcaaacaa aagtgcgtgt aattaaatac tattaatcat aggcagatac
2581 tattttgttt atgtttttgt ttttttcctg atgaaggcag aagagatggt ggtctattaa
2641 atatgaattg aatggagggt cctaatgcct tatttcaaaa caattcctca gggggaccag
2701 ctttggcttc atctttctct tgtgtggctt cacatttaaa ccagtatctt tattgaatta
2761 gaaaacaagt gggacatatt ttcctgagag cagcacagga atcttcttct tggcagctgc
2821 agtctgtcag gatgagatat cagattaggt tggataggtg gggaaatctg aagtgggtac
2881 attttttaaa ttttgctgtg tgggtcacac aaggtctaca ttacaaaaga cagaattcag
2941 ggatggaaag gagaatgaac aaatgtggga gttcatagtt ttccttgaat ccaactttta
3001 attaccagag taagttgcca aaatgtgatt gttgaagtac aaaaggaact atgaaaacca
3061 gaacaaattt taacaaaagg acaaccacag agggatatag tgaatatcgt atcattgtaa
3121 tcaaagaagt aaggaggtaa gattgccacg tgcctgctgg tactgtgatg catttcaagt
3181 ggcagtttta tcacgtttga atctaccatt catagccaga tgtgtatcag atgtttcact
3241 gacagttttt aacaataaat tcttttcact gtattttata tcacttataa taaatcggtg
3301 tataatttt
＜110〉Attached Tongji Hospital, Tongji Univ.
＜120〉pulmonary thromboembolism related gene and application thereof
<160>142
<210>61
<211>4048
<212>DNA
＜213〉human (Homo sapiens)
<400>61
1 ggctgcctcg caggggctgc gcgcagcggc aagaagtgtc tgggctggga cggacaggag
61 aggctgtcgc catcggcgtc ctgtgcccct ctgctccggc acggccctgt cgcagtgccc
121 gcgctttccc cggcgcctgc acgcggcgcg cctgggtaac atgcttgggg tcctggtcct
181 tggcgcgctg gccctggccg gcctggggtt ccccgcaccc gcagagccgc agccgggtgg
241 cagccagtgc gtcgagcacg actgcttcgc gctctacccg ggccccgcga ccttcctcaa
301 tgccagtcag atctgcgacg gactgcgggg ccacctaatg acagtgcgct cctcggtggc
361 tgccgatgtc atttccttgc tactgaacgg cgacggcggc gttggccgcc ggcgcctctg
421 gatcggcctg cagctgccac ccggctgcgg cgaccccaag cgcctcgggc ccctgcgcgg
481 cttccagtgg gttacgggag acaacaacac cagctatagc aggtgggcac ggctcgacct
541 caatggggct cccctctgcg gcccgttgtg cgtcgctgtc tccgctgctg aggccactgt
601 gcccagcgag ccgatctggg aggagcagca gtgcgaagtg aaggccgatg gcttcctctg
661 cgagttccac ttcccagcca cctgcaggcc actggctgtg gagcccggcg ccgcggctgc
721 cgccgtctcg atcacctacg gcaccccgtt cgcggcccgc ggagcggact tccaggcgct
781 gccggtgggc agctccgccg cggtggctcc cctcggctta cagctaatgt gcaccgcgcc
841 gcccggagcg gtccaggggc actgggccag ggaggcgccg ggcgcttggg actgcagcgt
901 ggagaacggc ggctgcgagc acgcgtgcaa tgcgatccct ggggctcccc gctgccagtg
961 cccagccggc gccgccctgc aggcagacgg gcgctcctgc accgcatccg cgacgcagtc
1021 ctgcaacgac ctctgcgagc acttctgcgt tcccaacccc gaccagccgg gctcctactc
1081 gtgcatgtgc gagaccggct accggctggc ggccgaccaa caccggtgcg aggacgtgga
1141 tgactgcata ctggagccca gtccgtgtcc gcagcgctgt gtcaacacac agggtggctt
1201 cgagtgccac tgctacccta actacgacct ggtggacggc gagtgtgtgg agcccgtgga
1261 cccgtgcttc agagccaact gcgagtacca gtgccagccc ctgaaccaaa ctagctacct
1321 ctgcgtctgc gccgagggct tcgcgcccat tccccacgag ccgcacaggt gccagatgtt
1381 ttgcaaccag actgcctgtc cagccgactg cgaccccaac acccaggcta gctgtgagtg
1441 ccctgaaggc tacatcctgg acgacggttt catctgcacg gacatcgacg agtgcgaaaa
1501 cggcggcttc tgctccgggg tgtgccacaa cctccccggt accttcgagt gcatctgcgg
1561 gcccgactcg gcccttgccc gccacattgg caccgactgt gactccggca aggtggacgg
1621 tggcgacagc ggctctggcg agcccccgcc cagcccgacg cccggctcca ccttgactcc
1681 tccggccgtg gggctcgtgc attcgggctt gctcataggc atctccatcg cgagcctgtg
1741 cctggtggtg gcgcttttgg cgctcctctg ccacctgcgc aagaagcagg gcgccgccag
1801 ggccaagatg gagtacaagt gcgcggcccc ttccaaggag gtagtgctgc agcacgtgcg
1861 gaccgagcgg acgccgcaga gactctgagc ggcctccgtc caggagcctg gctccgtcca
1921 ggagcctgtg cctcctcacc cccagctttg ctaccaaagc accttagctg gcattacagc
1981 tggagaagac cctccccgca ccccccaagc tgttttcttc tattccatgg ctaactggcg
2041 agggggtgat tagagggagg agaatgagcc tcggcctctt ccgtgacgtc actggaccac
2101 tgggcaatga tggcaatttt gtaacgaaga cacagactgc gatttgtccc aggtcctcac
2161 taccgggcgc aggagggtga gcgttattgg tcggcagcct tctgggcaga ccttgacctc
2221 gtgggctagg gatgactaaa atatttattt tttttaagta tttaggtttt tgtttgtttc
2281 ctttgttctt acctgtatgt ctccagtatc cactttgcac agctctccgg tctctctctc
2341 tctacaaact cccacttgtc atgtgacagg taaactatct tggtgaattt ttttttccta
2401 gccctctcac atttatgaag caagccccac ttattcccca ttcttcctag ttttctcctc
2461 ccaggaactg ggccaactca cctgagtcac cctacctgtg cctgacccta cttcttttgc
2521 tcttagctgt ctgctcagac agaaccccta catgaaacag aaacaaaaac actaaaaata
2581 aaaatggcca tttgcttttt caccagattt gctaatttat cctgaaattt cagattccca
2641 gagcaaaata attttaaaca aaggttgaga tgtaaaaggt attaaattga tgttgctgga
2701 ctgtcataga aattacaccc aaagaggtat ttatctttac ttttaaacag tgagcctgaa
2761 ttttgttgct gttttgattt gtactgaaaa atggtaattg ttgctaatct tcttatgcaa
2821 tttccttttt tgttattatt acttattttt gacagtgttg aaaatgttca gaaggttgct
2881 ctagattgag agaagagaca aacacctccc aggagacagt tcaagaaagc ttcaaactgc
2941 atgattcatg ccaattagca attgactgtc actgttcctt gtcactggta gaccaaaata
3001 aaaccagctc tactggtctt gtggaattgg gagcttggga atggatcctg gaggatgccc
3061 aattagggcc tagccttaat caggtcctca gagaatttct accatttcag agaggccttt
3121 tggaatgtgg cccctgaaca agaattggaa gctgccctgc ccatgggagc tggttagaaa
3181 tgcagaatcc taggctccac cccatccagt tcatgagaat ctatatttaa caagatctgc
3241 agggggtgtg tctgctcagt aatttgagga caaccattcc agactgcttc caattttctg
3301 gaatacatga aatatagatc agttataagt agcaggccaa gtcaggccct tattttcaag
3361 aaactgagga attttctttg tgtagctttg ctctttggta gaaaaggcta ggtacacagc
3421 tctagacact gccacacagg gtctgcaagg tctttggttc agctaagcta ggaatgaaat
3481 cctgcttcag tgtatggaaa taaatgtatc atagaaatgt aacttttgta agacaaaggt
3541 tttcctcttc tattttgtaa actcaaaata tttgtacata gttatttatt tattggagat
3601 aatctagaac acaggcaaaa tccttgctta tgacatcact tgtacaaaat aaacaaataa
3661 caatgtgctc tcgggttgtg tgtctgttca cttttcctcc ctcagtgccc tcattttatg
3721 tcattaaatg gggctcacaa accatgcaaa tgctatgaga tgcatggagg gctgccctgt
3781 accccagcac ttgtgttgtc tggtggtggc accatctctg attttcaaag ctttttccag
3841 aggctattat tttcactgta gaatgatttc atgctatctc tgtgtgcaca aatatttatt
3901 ttctttctgt aaccataaca acttcatata tgaggacttg tgtctctgtg cttttaaatg
3961 cataaatgca ttataggatc atttgttgga atgaattaaa taaacccttc ctggggcatc
4021 tggcgaatcc caaaaaaaaa aaaaaaaa
＜110〉Attached Tongji Hospital, Tongji Univ.
＜120〉pulmonary thromboembolism related gene and application thereof
<160>142
<210>62
<211>1806
<212>DNA
＜213〉human (Homo sapiens)
<400>62
1 agcctcgcca gagaagacaa gggcagaaag caccatgagt gggggcccaa tgggaggaag
61 gcccgggggc cgaggagcac cagcggttca gcagaacata ccctccaccc tcctccagga
121 ccacgagaac cagcgactct ttgagatgct tggacgaaaa tgcttgacgc tggccactgc
181 agttgttcag ctgtacctgg cgctgccccc tggagctgag cactggacca aggagcattg
241 tggggctgtg tgcttcgtga aggataaccc ccagaagtcc tacttcatcc gcctttacgg
301 ccttcaggct ggtcggctgc tctgggaaca ggagctgtac tcacagcttg tctactccac
361 ccccaccccc ttcttccaca ccttcgctgg agatgactgc caagcggggc tgaactttgc
421 agacgaggac gaggcccagg ccttccgggc cctcgtgcag gagaagatac aaaaaaggaa
481 tcagaggcaa agtggagaca gacgccagct acccccacca ccaacaccag ccaatgaaga
541 gagaagagga gggctcccac ccctgcccct gcatccaggt ggagaccaag gaggccctcc
601 agtgggtccg ctctccctgg ggctggcgac agtggacatc cagaaccctg acatcacgag
661 ttcacgatac cgtgggctcc cagcacctgg acctagccca gctgataaga aacgctcagg
721 gaagaagaag atcagcaaag ctgatattgg tgcacccagt ggattcaagc atgtcagcca
781 cgtggggtgg gacccccaga atggatttga cgtgaacaac ctcgacccag atctgcggag
841 tctgttctcc agggcaggaa tcagcgaggc ccagctcacc gacgccgaga cctctaaact
901 tatctacgac ttcattgagg accagggtgg gctggaggct gtgcggcagg agatgaggcg
961 ccaggagcca cttccgccgc ccccaccgcc atctcgagga gggaaccagc tcccccggcc
1021 ccctattgtg gggggtaaca agggtcgttc tggtccactg ccccctgtac ctttggggat
1081 tgccccaccc ccaccaacac cccggggacc cccaccccca ggccgagggg gccctccacc
1141 accaccccct ccagctactg gacgttctgg accactgccc cctccacccc ctggagctgg
1201 tgggccaccc atgccaccac caccgccacc accgccaccg ccgcccagct ccgggaatgg
1261 accagcccct cccccactcc ctcctgctct ggtgcctgcc gggggcctgg cccctggtgg
1321 gggtcgggga gcgcttttgg atcaaatccg gcagggaatt cagctgaaca agacccctgg
1381 ggccccagag agctcagcgc tgcagccacc acctcagagc tcagagggac tggtgggggc
1441 cctgatgcac gtgatgcaga agagaagcag agccatccac tcctccgacg aaggggagga
1501 ccaggctggc gatgaagatg aagatgatga atgggatgac tgagtggctg agttacttgc
1561 tgccctgtgc tcctccccgc aggacatggc tccccctcca cctgctctgt gcccaccctc
1621 cactctcctc ttccagggcc cccaaccccc catttcttcc ccaccaaccc ctccaatgct
1681 gttatccctg cctggtcctc acactcaccc aacaatccca aggccctttt tatacaaaaa
1741 ttctcagttc tcttcactca aggattttta aagaaaaata aaagaattgt ctttctgtct
1801 ctctat
＜110〉Attached Tongji Hospital, Tongji Univ.
＜120〉pulmonary thromboembolism related gene and application thereof
<160>142
<210>63
<211>1978
<212>DNA
＜213〉human (Homo sapiens)
<400>63
1 ctgctccgga gtgacgcggg cccgggcgcg acggtctcgg cggcggcggc ggcggcgaca
61 gagcgagcgc ggcgcggggc caccatgggg gcccagctca gcacgttggg ccatatggtg
121 ctcttcccag tctggttcct gtacagtctg ctcatgaagc tgttccagcg ctccacgcca
181 gccatcaccc tcgagagccc ggacatcaag tacccgctgc ggctcatcga ccgggagatc
241 atcagccatg acacccggcg cttccgcttt gccctgccgt caccccagca catcctgggc
301 ctccctgtcg gccagcacat ctacctctcg gctcgaattg atggaaacct ggtcgtccgg
361 ccctatacac ccatctccag cgatgatgac aagggcttcg tggacctggt catcaaggtt
421 tacttcaagg acacccatcc caagtttccc gctggaggga agatgtctca gtacctggag
481 agcatgcaga ttggagacac cattgagttc cggggcccca gtgggctgct ggtctaccag
541 ggcaaaggga agttcgccat ccgacctgac aaaaagtcca accctatcat caggacagtg
601 aagtctgtgg gcatgatcgc gggagggaca ggcatcaccc cgatgctgca ggtgatccgc
661 gccatcatga aggaccctga tgaccacact gtgtgccacc tgctctttgc caaccagacc
721 gagaaggaca tcctgctgcg acctgagctg gaggaactca ggaacaaaca ttctgcacgc
781 ttcaagctct ggtacacgct ggacagagcc cctgaagcct gggactacgg ccagggcttc
841 gtgaatgagg agatgatccg ggaccacctt ccacccccag aggaggagcc gctggtgctg
901 atgtgtggcc ccccacccat gatccagtac gcctgccttc ccaacctgga ccacgtgggc
961 caccccacgg agcgctgctt cgtcttctga gggccgggca cggtcacacg gccacccgcc
1021 ccgcgcaccc cacgccctgt tcacgctcac ccagtcacct ccccacatcg cacactgggg
1081 ccccgggttc agcctggcct gcccgtgccc tggtgaatca cctggctgag cagttcccct
1141 ggagcccctt cgggagcagg gctgtgtccc agatgggcca cggctgagcc ttcagagtac
1201 gtcctgcctg gcacttactg gtccttacca gagacgccca gccccatccc tgtcctcatg
1261 acccctcgtc caccccccac acacactata aggctgaggg ctgccagcag ccccgtctgc
1321 ccaccattcc cggccgtgga ccatagtcgg gatgtcagca gacacacatg ggcagcccaa
1381 agctgcaggt gccagggccc accccagcct cgcctgtcac ccccactccc gcctcagggc
1441 caggcccagg cctcaccacc tgacgctgca tgagacattg acaccagaaa gccctcttgg
1501 gggcactgct ccctacccca gggccctggc cagccgggag cttggctctc ctctggctag
1561 agtgggaaga gggggctggc catggggccc tcccagaacc tcagcatttc cttccagccc
1621 atccaaacac tgaggcagcc ttggggaacc ccgagctggg gggttggcag cccactgcac
1681 cgcctcaggg ttttggggtc ctgggctggg gccaccatcc ctgatggcag aactcccaca
1741 accacatgta tttattcctc tgtcctaaac cgtcccctcc ttccctcacc cccagcacag
1801 ggggattctg agcagtgcct cttgtctgag ggacatatca gtgacctcga cgttgccttt
1861 agactacagt tgtgttagcc tcttgcgtat tggctttttc agagtcattt atgagcagaa
1921 aaaaaaaaag taaaactttg ctaatattaa aaaaaaaaaa aaaaaaaaaa aaaaaaaa
＜110〉Attached Tongji Hospital, Tongji Univ.
＜120〉pulmonary thromboembolism related gene and application thereof
<160>142
<210>64
<211>6557
<212>DNA
＜213〉human (Homo sapiens)
<400>64
1 agagggcaag gagagagcag agaacacact ttgccttctc tttggtattg agtaatatca
61 accaaattgc agacatctca acactttggc caggcagcct gctgagcaag gtatttcagc
121 cagcatggca gcctctttcc cacccacctt gggactcagt tctgccccag atgaaattca
181 gcacccacat attaaatttt cagaatggaa atttaagctg ttccgggtga gatcctttga
241 aaagacacct gaagaagctc aaaaggaaaa gaaggattcc tttgagggga aaccctctct
301 ggagcaatct ccagcagtcc tggacaaggc tgatggtcag aagccagtcc caactcagcc
361 attgttaaaa gcccacccta agttttcaaa gaaatttcac gacaacgaga aagcaagagg
421 caaagcgatc catcaagcca accttcgaca tctctgccgc atctgtggga attcttttag
481 agctgatgag cacaacagga gatatccagt ccatggtcct gtggatggta aaaccctagg
541 ccttttacga aagaaggaaa agagagctac ttcctggccg gacctcattg ccaaggtttt
601 ccggatcgat gtgaaggcag atgttgactc gatccacccc actgagttct gccataactg
661 ctggagcatc atgcacagga agtttagcag tgccccatgt gaggtttact tcccgaggaa
721 cgtgaccatg gagtggcacc cccacacacc atcctgtgac atctgcaaca ctgcccgtcg
781 gggactcaag aggaagagtc ttcagccaaa cttgcagctc agcaaaaaac tcaaaactgt
841 gcttgaccaa gcaagacaag cccgtcagcg caagagaaga gctcaggcaa ggatcagcag
901 caaggatgtc atgaagaaga tcgccaactg cagtaagata catcttagta ccaagctcct
961 tgcagtggac ttcccagagc actttgtgaa atccatctcc tgccagatct gtgaacacat
1021 tctggctgac cctgtggaga ccaactgtaa gcatgtcttt tgccgggtct gcattctcag
1081 atgcctcaaa gtcatgggca gctattgtcc ctcttgccga tatccatgct tccctactga
1141 cctggagagt ccagtgaagt cctttctgag cgtcttgaat tccctgatgg tgaaatgtcc
1201 agcaaaagag tgcaatgagg aggtcagttt ggaaaaatat aatcaccaca tctcaagtca
1261 caaggaatca aaagagattt ttgtgcacat taataaaggg ggccggcccc gccaacatct
1321 tctgtcgctg actcggagag ctcagaagca ccggctgagg gagctcaagc tgcaagtcaa
1381 agcctttgct gacaaagaag aaggtggaga tgtgaagtcc gtgtgcatga ccttgttcct
1441 gctggctctg agggcgagga atgagcacag gcaagctgat gagctggagg ccatcatgca
1501 gggaaagggc tctggcctgc agccagctgt ttgcttggcc atccgtgtca acaccttcct
1561 cagctgcagt cagtaccaca agatgtacag gactgtgaaa gccatcacag ggagacagat
1621 ttttcagcct ttgcatgccc ttcggaatgc tgagaaggta cttctgccag gctaccacca
1681 ctttgagtgg cagccacctc tgaagaatgt gtcttccagc actgatgttg gcattattga
1741 tgggctgtct ggactatcat cctctgtgga tgattaccca gtggacacca ttgcaaagag
1801 gttccgctat gattcagctt tggtgtctgc tttgatggac atggaagaag acatcttgga
1861 aggcatgaga tcccaagacc ttgatgatta cctgaatggc cccttcactg tggtggtgaa
1921 ggagtcttgt gatggaatgg gagacgtgag tgagaagcat gggagtgggc ctgtagttcc
1981 agaaaaggca gtccgttttt cattcacaat catgaaaatt actattgccc acagctctca
2041 gaatgtgaaa gtatttgaag aagccaaacc taactctgaa ctgtgttgca agccattgtg
2101 ccttatgctg gcagatgagt ctgaccacga gacgctgact gccatcctga gtcctctcat
2161 tgctgagagg gaggccatga agagcagtga attaatgctt gagctgggag gcattctccg
2221 gactttcaag ttcatcttca ggggcaccgg ctatgatgaa aaacttgtgc gggaagtgga
2281 aggcctcgag gcttctggct cagtctacat ttgtactctt tgtgatgcca cccgtctgga
2341 agcctctcaa aatcttgtct tccactctat aaccagaagc catgctgaga acctggaacg
2401 ttatgaggtc tggcgttcca acccttacca tgagtctgtg gaagaactgc gggatcgggt
2461 gaaaggggtc tcagctaaac ctttcattga gacagtccct tccatagatg cactccactg
2521 tgacattggc aatgcagctg agttctacaa gatcttccag ctagagatag gggaagtgta
2581 taagaatccc aatgcttcca aagaggaaag gaaaaggtgg caggccacac tggacaagca
2641 tctccggaag aagatgaacc tcaaaccaat catgaggatg aatggcaact ttgccaggaa
2701 gctcatgacc aaagagactg tggatgcagt ttgtgagtta attccttccg aggagaggca
2761 cgaggctctg agggagctga tggatcttta cctgaagatg aaaccagtat ggcgatcatc
2821 atgccctgct aaagagtgcc cagaatccct ctgccagtac agtttcaatt cacagcgttt
2881 tgctgagctc ctttctacga agttcaagta taggtatgag ggaaaaatca ccaattattt
2941 tcacaaaacc ctggcccatg ttcctgaaat tattgagagg gatggctcca ttggggcatg
3001 ggcaagtgag ggaaatgagt ctggtaacaa actgtttagg cgcttccgga aaatgaatgc
3061 caggcagtcc aaatgctatg agatggaaga tgtcctgaaa caccactggt tgtacacctc
3121 caaatacctc cagaagttta tgaatgctca taatgcatta aaaacctctg ggtttaccat
3181 gaaccctcag gcaagcttag gggacccatt aggcatagag gactctctgg aaagccaaga
3241 ttcaatggaa ttttaagtag ggcaaccact tatgagttgg tttttgcaat tgagtttccc
3301 tctgggttgc attgagggct tctcctagca ccctttactg ctgtgtatgg ggcttcacca
3361 tccaagaggt ggtaggttgg agtaagatgc tacagatgct ctcaagtcag gaatagaaac
3421 tgatgagctg attgcttgag gcttttagtg agttccgaaa agcaacagga aaaatcagtt
3481 atctgaaagc tcagtaactc agaacaggag taactgcagg ggaccagaga tgagcaaaga
3541 tctgtgtgtg ttggggagct gtcatgtaaa tcaaagccaa ggttgtcaaa gaacagccag
3601 tgaggccaga aattggtctt gtggttttca tttttttccc ccttgattga ttatattttg
3661 tattgagata tgataagtgc cttctatttc atttttgaat aattcttcat ttttataatt
3721 ttacatatct tggcttgcta tataagattc aaaagagctt tttaaatttt tctaataata
3781 tcttacattt gtacagcatg atgaccttta caaagtgctc tcaatgcatt tacccattcg
3841 ttatataaat atgttacatc aggacaactt tgagaaaatc agtccttttt tatgtttaaa
3901 ttatgtatct attgtaacct tcagagttta ggaggtcatc tgctgtcatg gatttttcaa
3961 taatgaattt agaatacacc tgttagctac agttagttat taaatcttct gataatatat
4021 gtttacttag ctatcagaag ccaagtatga ttctttattt ttactttttc atttcaagaa
4081 atttagagtt tccaaattta gagcttctgc atacagtctt aaagccacag aggcttgtaa
4141 aaatataggt tagcttgatg tctaaaaata tatttcatgt cttactgaaa cattttgcca
4201 gactttctcc aaatgaaacc tgaatcaatt tttctaaatc taggtttcat agagtcctct
4261 cctctgcaat gtgttattct ttctataatg atcagtttac tttcagtgga ttcagaattg
4321 tgtagcagga taaccttgta tttttccatc cgctaagttt agatggagtc caaacgcagt
4381 acagcagaag agttaacatt tacacagtgc tttttaccac tgtggaatgt tttcacactc
4441 atttttcctt acaacaattc tgaggagtag gtgttgttat tatctccatt tgatgggggt
4501 ttaatgattt gctcaaagtc atttaggggt aataaatact tggcttggaa atttaacaca
4561 gtccttttgt ctccaaagcc cttcttcttt ccaccacaaa ttaatcacta tgtttataag
4621 gtagtatcag aattttttta ggattcacaa ctaatcacta tagcacatga ccttgggatt
4681 acatttttat ggggcagggg taagcggctt ttaaatcatt tgtgtgctct ggctcttttg
4741 atagaagaaa gcaacacaaa agctccaaag ggccccctaa ccctcttgtg gctccagtta
4801 tttggaaact atgatctgca tccttaggaa tctgggattt gccagttgct ggcaatgtag
4861 agcaggcatg gaattttata tgctagtgag tcataatgat atgttagtgt taattagttt
4921 ttcttccttt gattttattg gccataattg ctactcttca tacacagtat atcaaagagc
4981 ttgataattt agttgtcaaa agtgcatcgg cgacattatc tttaattgta tgtatttggt
5041 gcttcttcag ggattgaact cagtatcttt cattaaaaaa cacagcagtt ttccttgctt
5101 tttatatgca gaatatcaaa gtcatttcta atttagttgt caaaaacata tacatatttt
5161 aacattagtt tttttgaaaa ctcttggttt tgtttttttg gaaatgagtg ggccactaag
5221 ccacactttc ccttcatcct gcttaatcct tccagcatgt ctctgcacta ataaacagct
5281 aaattcacat aatcatccta tttactgaag catggtcatg ctggtttata gattttttac
5341 ccatttctac tctttttctc tattggtggc actgtaaata ctttccagta ttaaattatc
5401 cttttctaac actgtaggaa ctattttgaa tgcatgtgac taagagcatg atttatagca
5461 caacctttcc aataatccct taatcagatc acattttgat aaaccctggg aacatctggc
5521 tgcaggaatt tcaatatgta gaaacgctgc ctatggtttt ttgcccttac tgttgagact
5581 gcaatatcct agaccctagt tttatactag agttttattt ttagcaatgc ctattgcaag
5641 tgcaattata tactccaggg aaattcacca cactgaatcg agcatttgtg tgtgtatgtg
5701 tgaagtatat ctgggacttc agaagtgcaa tgtatttttc tcctgtgaaa cctgaatcta
5761 caagttttct gccaagccac tcaggtgcat tgcagggacc agtgataatg gctgatgaaa
5821 attgatgatt ggtcagtgag gtcaaaagga gccttgggat taataaacat gcactgagaa
5881 gcaagaggag gagaaaaaga tgtctttttc ttccaggtga actggaattt agttttgcct
5941 cagatttttt tcccacaaga tacagaagaa gataaagatt tttttggttg agagtgtggg
6001 tcttgcatta catcaaacag agttcaaatt ccacacagat aagaggcagg atatataagc
6061 gccagtggta gttgggagga ataaaccatt atttggatgc aggtggtttt tgattgcaaa
6121 tatgtgtgtg tcttcagtga ttgtatgaca gatgatgtat tcttttgatg ttaaaagatt
6181 ttaagtaaga gtagatacat tgtacccatt ttacattttc ttattttaac tacagtaatc
6241 tacataaata tacctcagaa atcatttttg gtgattattt tttgttttgt agaattgcac
6301 ttcagtttat tttcttacaa ataaccttac attttgttta atggcttcca agagcctttt
6361 tttttttgta tttcagagaa aattcaggta ccaggatgca atggatttat ttgattcagg
6421 ggacctgtat ttccatgtca aatgttttca aataaaatga aatatgagtt tcaatacttt
6481 ttatatttta atatttcctt aatattatgg ttattgtccg ccattttgtt gtatattgta
6541 aataaagttt agattgt
＜110〉Attached Tongji Hospital, Tongji Univ.
＜120〉pulmonary thromboembolism related gene and application thereof
<160>142
<210>65
<211>1559
<212>DNA
＜213〉human (Homo sapiens)
<400>65
1 aaagaaccag ttttcaggcg gattgcctca gatcacacta tctccacttg cccagccctg
61 tggaagatta gcggccatgt attccaatgt gataggaact gtaacctctg gaaaaaggaa
121 ggtttatctt ttgtccttgc tgctcattgg cttctgggac tgcgtgacct gtcacgggag
181 ccctgtggac atctgcacag ccaagccgcg ggacattccc atgaatccca tgtgcattta
241 ccgctccccg gagaagaagg caactgagga tgagggctca gaacagaaga tcccggaggc
301 caccaaccgg cgtgtctggg aactgtccaa ggccaattcc cgctttgcta ccactttcta
361 tcagcacctg gcagattcca agaatgacaa tgataacatt ttcctgtcac ccctgagtat
421 ctccacggct tttgctatga ccaagctggg tgcctgtaat gacaccctcc agcaactgat
481 ggaggtattt aagtttgaca ccatatctga gaaaacatct gatcagatcc acttcttctt
541 tgccaaactg aactgccgac tctatcgaaa agccaacaaa tcctccaagt tagtatcagc
601 caatcgcctt tttggagaca aatcccttac cttcaatgag acctaccagg acatcagtga
661 gttggtatat ggagccaagc tccagcccct ggacttcaag gaaaatgcag agcaatccag
721 agcggccatc aacaaatggg tgtccaataa gaccgaaggc cgaatcaccg atgtcattcc
781 ctcggaagcc atcaatgagc tcactgttct ggtgctggtt aacaccattt acttcaaggg
841 cctgtggaag tcaaagttca gccctgagaa cacaaggaag gaactgttct acaaggctga
901 tggagagtcg tgttcagcat ctatgatgta ccaggaaggc aagttccgtt atcggcgcgt
961 ggctgaaggc acccaggtgc ttgagttgcc cttcaaaggt gatgacatca ccatggtcct
1021 catcttgccc aagcctgaga agagcctggc caaggtagag aaggaactca ccccagaggt
1081 gctgcaagag tggctggatg aattggagga gatgatgctg gtggtccaca tgccccgctt
1141 ccgcattgag gacggcttca gtttgaagga gcagctgcaa gacatgggcc ttgtcgatct
1201 gttcagccct gaaaagtcca aactcccagg tattgttgca gaaggccgag atgacctcta
1261 tgtctcagat gcattccata aggcatttct tgaggtaaat gaagaaggca gtgaagcagc
1321 tgcaagtacc gctgttgtga ttgctggccg ttcgctaaac cccaacaggg tgactttcaa
1381 ggccaacagg cctttcctgg tttttataag agaagttcct ctgaacacta ttatcttcat
1441 gggcagagta gccaaccctt gtgttaagta aaatgttctt attctttgca cctcttccta
1501 tttttggttt gtgaacagaa gtaaaaataa atacaaacta cttccatctc acattaaaa
＜110〉Attached Tongji Hospital, Tongji Univ.
＜120〉pulmonary thromboembolism related gene and application thereof
<160>142
<210>66
<211>1502
<212>DNA
＜213〉human (Homo sapiens)
<400>66
1 cagggacaca gtactcggcc acaccatggg gcgcccactg cacctcgtcc tgctcagtgc
61 ctccctggct ggcctcctgc tgctcgggga aagtctgttc atccgcaggg agcaggccaa
121 caacatcctg gcgagggtca cgagggccaa ttcctttctt gaagagatga agaaaggaca
181 cctcgaaaga gagtgcatgg aagagacctg ctcatacgaa gaggcccgcg aggtctttga
241 ggacagcgac aagacgaatg aattctggaa taaatacaaa gatggcgacc agtgtgagac
301 cagtccttgc cagaaccagg gcaaatgtaa agacggcctc ggggaataca cctgcacctg
361 tttagaagga ttcgaaggca aaaactgtga attattcaca cggaagctct gcagcctgga
421 caacggggac tgtgaccagt tctgccacga ggaacagaac tctgtggtgt gctcctgcgc
481 ccgcgggtac accctggctg acaacggcaa ggcctgcatt cccacagggc cctacccctg
541 tgggaaacag accctggaac gcaggaagag gtcagtggcc caggccacca gcagcagcgg
601 ggaggcccct gacagcatca catggaagcc atatgatgca gccgacctgg accccaccga
661 gaaccccttc gacctgcttg acttcaacca gacgcagcct gagaggggcg acaacaacct
721 caccaggatc gtgggaggcc aggaatgcaa ggacggggag tgtccctggc aggccctgct
781 catcaatgag gaaaacgagg gtttctgtgg tggaaccatt ctgagcgagt tctacatcct
841 aacggcagcc cactgtctct accaagccaa gagattcaag gtgagggtag gggaccggaa
901 cacggagcag gaggagggcg gtgaggcggt gcacgaggtg gaggtggtca tcaagcacaa
961 ccggttcaca aaggagacct atgacttcga catcgccgtg ctccggctca agacccccat
1021 caccttccgc atgaacgtgg cgcctgcctg cctccccgag cgtgactggg ccgagtccac
1081 gctgatgacg cagaagacgg ggattgtgag cggcttcggg cgcacccacg agaagggccg
1141 gcagtccacc aggctcaaga tgctggaggt gccctacgtg gaccgcaaca gctgcaagct
1201 gtccagcagc ttcatcatca cccagaacat gttctgtgcc ggctacgaca ccaagcagga
1261 ggatgcctgc cagggggaca gcgggggccc gcacgtcacc cgcttcaagg acacctactt
1321 cgtgacaggc atcgtcagct ggggagaggg ctgtgcccgt aaggggaagt acgggatcta
1381 caccaaggtc accgccttcc tcaagtggat cgacaggtcc atgaaaacca ggggcttgcc
1441 caaggccaag agccatgccc cggaggtcat aacgtcctct ccattaaagt gagatcccac
1501 tc
＜110〉Attached Tongji Hospital, Tongji Univ.
＜120〉pulmonary thromboembolism related gene and application thereof
<160>142
<210>67
<211>1997
<212>DNA
＜213〉human (Homo sapiens)
<400>67
1 aattcctcag tgacccagga gctgacacac tatggcgcac gtccgaggct tgcagctgcc
61 tggctgcctg gccctggctg ccctgtgtag ccttgtgcac agccagcatg tgttcctggc
121 tcctcagcaa gcacggtcgc tgctccagcg ggtccggcga gccaacacct tcttggagga
181 ggtgcgcaag ggcaacctag agcgagagtg cgtggaggag acgtgcagct acgaggaggc
241 cttcgaggct ctggagtcct ccacggctac ggatgtgttc tgggccaagt acacagcttg
301 tgagacagcg aggacgcctc gagataagct tgctgcatgt ctggaaggta actgtgctga
361 gggtctgggt acgaactacc gagggcatgt gaacatcacc cggtcaggca ttgagtgcca
421 gctatggagg agtcgctacc cacataagcc tgaaatcaac tccactaccc atcctggggc
481 cgacctacag gagaatttct gccgcaaccc cgacagcagc accacgggac cctggtgcta
541 cactacagac cccaccgtga ggaggcagga atgcagcatc cctgtctgtg gccaggatca
601 agtcactgta gcgatgactc cacgctccga aggctccagt gtgaatctgt cacctccatt
661 ggagcagtgt gtccctgatc gggggcagca gtaccagggg cgcctggcgg tgaccacaca
721 tgggctcccc tgcctggcct gggccagcgc acaggccaag gccctgagca agcaccagga
781 cttcaactca gctgtgcagc tggtggagaa cttctgccgc aacccagacg gggatgagga
841 gggcgtgtgg tgctatgtgg ccgggaagcc tggcgacttt gggtactgcg acctcaacta
901 ttgtgaggag gccgtggagg aggagacagg agatgggctg gatgaggact cagacagggc
961 catcgaaggg cgtaccgcca ccagtgagta ccagactttc ttcaatccga ggacctttgg
1021 ctcgggagag gcagactgtg ggctgcgacc tctgttcgag aagaagtcgc tggaggacaa
1081 aaccgaaaga gagctcctgg aatcctacat cgacgggcgc attgtggagg gctcggatgc
1141 agagatcggc atgtcacctt ggcaggtgat gcttttccgg aagagtcccc aggagctgct
1201 gtgtggggcc agcctcatca gtgaccgctg ggtcctcacc gccgcccact gcctcctgta
1261 cccgccctgg gacaagaact tcaccgagaa tgaccttctg gtgcgcattg gcaagcactc
1321 ccgcacaagg tacgagcgaa acattgaaaa gatatccatg ttggaaaaga tctacatcca
1381 ccccaggtac aactggcggg agaacctgga ccgggacatt gccctgatga agctgaagaa
1441 gcctgttgcc ttcagtgact acattcaccc tgtgtgtctg cccgacaggg agacggcagc
1501 cagcttgctc caggctggat acaaggggcg ggtgacaggc tggggcaacc tgaaggagac
1561 gtggacagcc aacgttggta aggggcagcc cagtgtcctg caggtggtga acctgcccat
1621 tgtggagcgg ccggtctgca aggactccac ccggatccgc atcactgaca acatgttctg
1681 tgctggttac aagcctgatg aagggaaacg aggggatgcc tgtgaaggtg acagtggggg
1741 accctttgtc atgaagagcc cctttaacaa ccgctggtat caaatgggca tcgtctcatg
1801 gggtgaaggc tgtgaccggg atgggaaata tggcttctac acacatgtgt tccgcctgaa
1861 gaagtggata cagaaggtca ttgatcagtt tggagagtag gggccactca tattctgggc
1921 tcctggaacc aatcccgtga aagaattatt tttgtgtttc taaaactatg gttcccaata
1981 aaagtgactc tcagcgg
＜110〉Attached Tongji Hospital, Tongji Univ.
＜120〉pulmonary thromboembolism related gene and application thereof
<160>142
<210>68
<211>3655
<212>DNA
＜213〉human (Homo sapiens)
<400>68
1 agcaatcctt tctttcagct ggagtgctcc tcaggagcca gccccaccct tagaaaagat
61 gttttccatg aggatcgtct gcctggtcct aagtgtggtg ggcacagcat ggactgcaga
121 tagtggtgaa ggtgactttc tagctgaagg aggaggcgtg cgtggcccaa gggttgtgga
181 aagacatcaa tctgcctgca aagattcaga ctggcccttc tgctctgatg aagactggaa
241 ctacaaatgc ccttctggct gcaggatgaa agggttgatt gatgaagtca atcaagattt
301 tacaaacaga ataaataagc tcaaaaattc actatttgaa tatcagaaga acaataagga
36l ttctcattcg ttgaccacta atataatgga aattttgaga ggcgattttt cctcagcaaa
42l taaccgtgat aatacctaca accgagtgtc agaggatctg agaagcagaa ttgaagtcct
48l gaagcgcaaa gtcatagaaa aagtacagca tatccagctt ctgcagaaaa atgttagagc
54l tcagttggtt gatatgaaac gactggaggt ggacattgat attaagatcc gatcttgtcg
60l agggtcatgc agtagggctt tagctcgtga agtagatctg aaggactatg aagatcagca
66l gaagcaactt gaacaggtca ttgccaaaga cttacttccc tctagagata ggcaacactt
721 accactgata aaaatgaaac cagttccaga cttggttccc ggaaatttta agagccagct
781 tcagaaggta cccccagagt ggaaggcatt aacagacatg ccgcagatga gaatggagtt
84l agagagacct ggtggaaatg agattactcg aggaggctcc acctcttatg gaaccggatc
90l agagacggaa agccccagga accctagcag tgctggaagc tggaactctg ggagctctgg
961 acctggaagt actggaaacc gaaaccctgg gagctctggg actggaggga ctgcaacctg
102l gaaacctggg agctctggac ctggaagtac tggaagctgg aactctggga gctctggaac
1081 tggaagtact ggaaaccaaa accctgggag ccctagacct ggtagtaccg gaacctggaa
l14l tcctggcagc tctgaacgcg gaagtgctgg gcactggacc tctgagagct ctgtatctgg
1201 tagtactgga caatggcact ctgaatctgg aagttttagg ccagatagcc caggctctgg
1261 gaacgcgagg cctaacaacc cagactgggg cacatttgaa gaggtgtcag gaaatgtaag
132l tccagggaca aggagagagt accacacaga aaaactggtc acttctaaag gagataaaga
138l gctcaggact ggtaaagaga aggtcacctc tggtagcaca accaccacgc gtcgttcatg
1441 ctctaaaacc gttactaaga ctgttattgg tcctgatggt cacaaagaag ttaccaaaga
150l agtggtgacc tccgaagatg gttctgactg tcccgaggca atggatttag gcacattgtc
1561 tggcataggt actctggatg ggttccgcca taggcaccct gatgaagctg ccttcttcga
162l cactgcctca actggaaaaa cattcccagg tttcttctca cctatgttag gagagtttgt
168l cagtgagact gagtctaggg gctcagaatc tggcatcttc acaaatacaa aggaatccag
1741 ttctcatcac cctgggatag ctgaattccc ttcccgtggt aaatcttcaa gttacagcaa
1801 acaatttact agtagcacga gttacaacag aggagactcc acatttgaaa gcaagagcta
1861 taaaatggca gatgaggccg gaagtgaagc cgatcatgaa ggaacacata gcaccaagag
192l aggccatgct aaatctcgcc ctgtcagaga ctgtgatgat gtcctccaaa cacatccttc
198l aggtacccaa agtggcattt tcaatatcaa gctaccggga tccagtaaga ttttttctgt
2041 ttattgcgat caagagacca gtttgggagg atggcttttg atccagcaaa gaatggatgg
210l atcactgaat tttaaccgga cctggcaaga ctacaagaga ggtttcggca gcctgaatga
216l cgagggggaa ggagaattct ggctaggcaa tgactacctc cacttactaa cccaaagggg
222l ctctgttctt agggttgaat tagaggactg ggctgggaat gaagcttatg cagaatatca
228l cttccgggta ggctctgagg ctgaaggcta tgccctccaa gtctcctcct atgaaggcac
234l tgcgggtgat gctctgattg agggttccgt agaggaaggg gcagagtaca cctctcacaa
240l caacatgcag ttcagcacct ttgacaggga tgcagaccag tgggaagaga actgtgcaga
2461 agtctatggg ggaggctggt ggtataataa ctgccaagca gccaatctca atggaatcta
2521 ctaccctggg ggctcctatg acccaaggaa taacagtcct tatgagattg agaatggagt
258l ggtctgggtt tcctttagag gggcagatta ttccctcagg gctgttcgca tgaaaattag
264l gccccttgtg acccaatagg ctgaagaagt gggaatggga gcactctgtc ttctttgcta
2701 gagaagtgga gagaaaatac aaaaggtaaa gcagttgaga ttctctacaa cctaaaaaat
2761 tcctaggtgc tattttctta tcctttgtac tgtagctaaa tgtacctgag acatattagt
2821 ctttgaaaaa taaagttatg taaggttttt tttatcttta aatagctctg tgggttttaa
2881 catttttata aagatatacc aagggccatt cagtacatca ggaaagtggc agacagaagc
2941 ttctctctgc aaccttgaag actattggtt tgagaacttc tcttcccata ccacccaaaa
3001 tcataatgcc attggaaagc aaaaagttgt tttatccatt tgatttgaat tgttttaagc
306l caatatttta aggtaaaact cactgaatct aaccatagct gacctttgta gtagaattta
312l caacttataa ttacaatgca caatttataa ttacaatatg tatttatgtc ttttgctatg
3181 gagcaaatcc aggaaggcaa gagaaacatt ctttcctaaa tataaatgaa aatctatcct
3241 ttaaactctt ccactagacg ttgtaatgca cacttatttt tttcccaagg agtaaccaat
3301 ttctttctaa aacacattta aaattttaaa actatttatg aatattaaaa aaagacataa
3361 ttcacacatt aataaacaat ctcccaagta ttgatttaac ttcatttttc taataatcat
3421 aaactatatt ctgtgacatg ctaattatta ttaaatgtaa gtcgttagtt cgaaagcctc
3481 tcactaagta tgatctatgc tatattcaaa attcaaccca tttactttgg tcaatatttg
3541 atctaagttg catctttaat cctggtggtc ttgccttctg atttttaatt tgtatccttt
3601 tctattaaga tatatttgtc attttctctt gaatatgtat taaaatatcc caagc
＜110〉Attached Tongji Hospital, Tongji Univ.
＜120〉pulmonary thromboembolism related gene and application thereof
<160>142
<210>69
<211>7633
<212>DNA
＜213〉human (Homo sapiens)
<400>69
1 gggccggggg gcggagcctt gcgggctgga gcgaaagaat gcgggggctg agcgcagaag
61 cggctcgagg ctggaagagg atcttgggcg ccgccaggtt ctgtggacaa tcacaatggg
121 aatccaagga gggtctgtcc tgttcgggct gctgctcgtc ctggctgtct tctgccattc
181 aggtcatagc ctgcagtgct acaactgtcc taacccaact gctgactgca aaacagccgt
241 caattgttca tctgattttg atgcgtgtct cattaccaaa gctgggttac aagtgtataa
301 caagtgttgg aagtttgagc attgcaattt caacgacgtc acaacccgct tgagggaaaa
361 tgagctaacg tactactgct gcaagaagga cctgtgtaac tttaacgaac agcttgaaaa
421 tggtgggaca tccttatcag agaaaacagt tcttctgctg gtgactccat ttctggcagc
481 agcctggagc cttcatccct aagtcaacac caggagagct tctcccaaac tccccgttcc
541 tgcgtagtcc gctttctctt gctgccacat tctaaaggct tgatattttc caaatggatc
601 ctgttgggaa agaataaaat tagcttgagc aacctggcta agatagaggg gctctgggag
661 actttgaaga ccagtcctgt ttgcagggaa gccccacttg aaggaagaag tctaagagtg
721 aagtaggtgt gacttgaact agattgcatg cttcctcctt tgctcttggg aagaccagct
781 ttgcagtgac agcttgagtg ggttctctgc agccctcaga ttatttttcc tctggctcct
841 tggatgtagt cagttagcat cattagtaca tctttggagg gtggggcagg agtatatgag
901 catcctctct cacatggaac gctttcataa acttcaggga tcccgtgttg ccatggaggc
961 atgccaaatg ttccatatgt gggtgtcagt cagggacaac aagatcctta atgcagagct
1021 agaggacttc tggcagggaa gtggggaagt gttccagata gcagggcatg aaaacttaga
1081 gaggtacaag tggctgaaaa tcgagttttt cctctgtctt taaattttat atgggctttg
1141 ttatcttcca ctggaaaagt gtaatagcat acatcaatgg tgtgttaaag ctatttcctt
1201 gccttttttt tattggaatg gtaggatatc ttggctttgc cacacacagt tacagagtga
1261 acactctact acatgtgact ggcagtatta agtgtgctta ttttaaatgt tactggtaga
1321 aaggcagttc aggtatgtgt gtatatagta tgaatgcagt ggggacaccc tttgtggtta
1381 cagtttgaga cttccaaagg tcatccttaa taacaacaga tctgcagggg tatgttttac
1441 catctgcatc cagcctcctg ctaactccta gctgactcag catagattgt ataaaatacc
1501 tttgtaacgg ctcttagcac actcacagat gtttgaggct ttcagaagct cttctaaaaa
1561 atgatacaca cctttcacaa gggcaaactt tttccttttc cctgtgtatt ctagtgaatg
1621 aatctcaaga ttcagtagac ctaatgacat ttgtatttta tgatcttggc tgtatttaat
1681 ggcataggct gacttttgca gatggaggaa tttcttgatt aatgttgaaa aaaaaccctt
1741 gattatactc tgttggacaa accgagtgca atgaatgatg cttttctgaa aatgaaatat
1801 aacaagtggg tgaatgtggt tatggccgaa aaggatatgc agtatgctta atggtagcaa
1861 ctgaaagaag acatcctgag cagtgccagc tttcttctgt tgatgccgtt ccctgaacat
1921 aggaaaatag aaacttgctt atcaaaactt agcattacct tggtgctctg tgttctctgt
1981 tagctcagtg tctttcctta catcaatagg tttttttttt tttttttggc ctgaggaagt
2041 actgaccatg cccacagcca ccggctgagc aaagaagctc atttcatgtg agttctaagg
2101 aatgagaaac aattttgatg aatttaagca gaaaatgaat ttctgggaac ttttttgggg
2161 gcggggggtt ggggaattca gccacactcc agaaagccag gagtcgacag ttttggaagc
2221 ctctctcagg attgagattc taggatgaga ttggcttact gctatcttgt gtcatgtacc
2281 cactttttgg ccagactaca ctgggaagaa ggtagtcctc taaagcaaaa tctgagtgcc
2341 actaaatggg gagatggggc tgttaagctg tccaaatcaa caagggtcat ataaatggcc
2401 ttaaactttg gggttgcttt ctgcaaaaag ttgctgtgac tcatgccata gacaaggttg
2461 agtgcctgga cccaaaggca atactgtaat gtaaagacat ttatagtact aggcaaacag
2521 caccccaggt actccaggcc ctcctggctg gagagggctg tggcaataga aaattagtgc
2581 caactgcagt gagtcagcct aggttaaata gagagtgtaa gagtgctgga caggaacctc
2641 caccctcatg tcacatttct tcaatgtgac ccttctggcc cctctcctcc tgacagcgga
2701 acaatgactg ccccgatagg tgaggctgga ggaagaatca gtcctgtcct tggcaagctc
2761 ttcactatga cagtaaaggc tctctgcctg ctgccaaggc ctgtgacttt ctaacctggc
2821 ctcacgctgg gtaagcttaa ggtagaggtg caggattagc aagcccacct ggctaccagg
2881 ccgacagcta catcctccaa ctgaccctga tcaacgaaga gggattcatg tgtctgtctc
2941 agttggttcc aaatgaaacc agggagcagg ggagttagga atcgaacacc agtcatgcct
3001 actggctctc tgctcgagag ccaataccct gtgccctcca ctcatctgga tttacaggaa
3061 ctgtcatagt gttcagtatt gggtggtgat aagcccattg gattgtcccc ttggggggat
3121 gagctagggg tgcaaggaac acctgatgag tagataagtg gagctcatgg tatttcctga
3181 aagatgctaa tctatttgcc aaacttggtc ttgaatgtac tgggggcttc aaggtatggg
3241 tatatttttc ttgtgtcctt gcagttagcc cccatgtctt atgtgtgtcc tgaaaaaata
3301 agagcctgcc caagactttg ggcctcttga cagaattaac cacttttata catctgagtt
3361 ctcttggtaa gttctttagc agtgttcaaa gtctactagc tcgcattagt ttctgttgct
3421 gccaacagat ctgaactaat gctaacagat ccccctgagg gattcttgat gggctgagca
3481 gctggctgga gctagtactg actgacattc attgtgatga gggcagcttt ctggtacagg
3541 attctaagct ctatgtttta tatacatttt catctgtact tgcacctcac tttacacaag
3601 aggaaactat gcaaagttag ctggatcgct caaggtcact taggtaagtt ggcaagtcca
3661 tgcttcccac tcagctcctc aggtcagcaa gtctacttct ctgcctattt tgtatactct
3721 ctttaatatg tgcctagctt tggaaagtct agaatgggtc cctggtgcct ttttactttg
3781 aagaaatcag tttctgcctc tttttggaaa agaaaacaaa gtgcaattgt tttttactgg
3841 aaagttaccc aatagcatga ggtgaacagg acgtagttag gccttcctgt aaacagaaaa
3901 tcatatcaaa acactatctt cccatctgtt tctcaatgcc tgctacttct tgtagatatt
3961 tcatttcagg agagcagcag ttaaacccgt ggattttgta gttaggaacc tgggttcaaa
4021 ccctcttcca ctaattggct atgtctctgg acaagttttt tttttttttt ttttttaaac
4081 cctttctgaa ctttcacttt ctatgtctac ctcaaagaat tgttgtgagg cttgagataa
4141 tgcatttgta aagggtctgc cagataggaa gatgctagtt atggatttac aaggttgtta
4201 aggctgtaag agtctaaaac ctacagtgaa tcacaatgca tttaccccca ctgacttgga
4261 cataagtgaa aactagccag aagtctcttt ttcaaattac ttacaggtta ttcaatataa
4321 aatttttgta atggataatc ttatttatct aaactaaagc ttcctgttta tacacactcc
4381 tgttattctg ggataagata aatgaccaca gtaccttaat ttctaggtgg gtgcctgtga
4441 tggttcattg taggtaagga cattttctct ttttcagcag ctgtgtaggt ccagagcctc
4501 tgggagagga ggggggtagc atgcacccag caggggactg aactgggaaa ctcaaggttc
4561 tttttactgt ggggtagtga gctgcctttc tgtgatcggt ttccctaggg atgttgctgt
4621 tcccctcctt gctattcgca gctacataca acgtggccaa ccccagtagg ctgatcctat
4681 atatgatcag tgctggtgct gactctcaat agccccaccc aagctggcta taggtttaca
4741 gatacattaa ttaggcaacc taaaatattg atgctggtgt tggtgtgaca taatgctatg
4801 gccagaactg aaacttagag ttataattca tgtattaggg ttctccagag ggacagaatt
4861 agtaggatat atgtatatat gaaagggagg ttattaggga gaactggctc ccacagttag
4921 aaggcgaagt cgcacaatag gccgtctgca agctgggtta gagagaagcc agtagtggct
4981 cagcctgagt tcaaaaacct caaaactggg gaagctgaca gtgcagccag ccttcagtct
5041 gtggccaaag gcccaagagc ccctggcaac caacccactg gtgcaagtcc tagattccaa
5101 aggctgaaga acctggagtc tgatgtccaa gagcaggaag agtggaagaa agccagaaga
5161 ctcagcaaac aaggtagaca gtgtctacca ccatagtggc cataccaaag aggctaccga
5221 ttccttcctg ctacctggat ccctgaagtt gccctggtct ctgcaccttc taaacctagt
5281 tcttaagagc tttccattac atgagctgtc tcaaagccct ccaataaatt ctcagtgtaa
5341 gcttctgttg cttgtggaca gaaaattctg acagacctac cctataagtg ttactgtcag
5401 gataacatga gaacgcacaa cagtaagtgg tcactaagtg ttagctacgg ttattttgcc
5461 caaggtagca tggctagttg atgccggttg atggggctta aacccagctc cctcatcttc
5521 caggcctctg tactccctat tccactaaac tacctctcag gtttattttt ttaaattctt
5581 actctgcaag tacataggac cacatttacc tgggaaaaca agaataaagg ctgctctgca
5641 ttttttagaa acttttttga aagggagatg ggaatgcctg cacccccaag tccagaccaa
5701 cacaatggtt aattgagatg aataataaag gaaagactgt tctgggcttc ccagaatagc
5761 ttggtcctta aattgtggca caaacaacct cctgtcagag ccagcctcct gccaggaaga
5821 ggggtaggag actagaggcc gtgtgtgcag ccttgccctg aaggctaggg tgacaatttg
5881 gaggctgtcc aaacaccctg gcctctagag ctggcctgtc tatttgaaat gccggctctg
5941 atgctaatcg gcgaccctca ggcaagttac ttaaccttac atgcctcagt tttctcatct
6001 ggaaaatgag aaccctaggt ttagggttgt tagaaaagtt aaatgagtta agacaagtgc
6061 ctgggacaca gtagcctctt gtgtgtgttt atcattatgt cctcagcagg tcgtagaagc
6121 agcttctcag gtgtgaggct ggcgcattat ctggagtggg ttgggttttc taggatggac
6181 cccctgctgc attttcctca ttcatccacc agggcttaat ggggaatcaa ggaatccatg
6241 tgtaactgta taataactgt agccacactc caatgaccac ctactagttg tccctggcac
6301 tgcttataca tatgtccatc aaatcaatcc tatgaagtag atactgtctt cattttatag
6361 atcagagaca attggggttc agagagctga tgtgattttc ccagggtcac agagagtccc
6421 agattcaggc acaactcttg tattccaaga cacaaccact acatgtccaa aggctgccca
6481 gagccaccgg gcacggcaaa ttgtgacata tccctaaaga ggctgagcac ctggtcagga
6541 tctgatggct gacagtgtgt ccagatgcag agctggagtg ggggagggga aggggggctc
6601 cttgggacag agaaggcttt ctgtgctttc tctgaaggga gcagtctgag gaccaaggga
6661 acccggcaaa cagcacctca ggtactccag gccctcctgg ctggagaggg ctgtggcaat
6721 ggaaaattag tgccaactgc aatgagtcag cctcggttaa atagagagtg aagaatgctg
6781 gacaggaacc tccaccctca tgtcacattt cttcagtgtg acccttctgg cccctctcct
6841 cctgacagcg gaacaatgac tgccccgata ggtgaggctg gaggaagaat cagtcctgtc
6901 cttggcaagc tcttcactat gacagtaaag gctctctgcc tgctgccaag gcctgtgact
6961 ttctaacctg gcctcacgct gggtaagctt aaggtagagg tgcaggatta gcaagcccac
7021 ctggctacca ggccgacagc tacatctttc aactgaccct gatcaacgaa gagggacttg
7081 tgtctctcag ttggttccaa atgaaaccag ggagcagggg cgttaggaag ctccaacagg
7141 atggtactta atggggcatt tgagtggaga ggtaggtgac atagtgcttt ggagcccagg
7201 gagggaaagg ttctgctgaa gttgaattca agactgttct ttcatcacaa acttgagttt
7261 cctggacatt tgtttgcaga aacaaccgta gggttttgcc ttaacctcgt gggtttatta
7321 ttacctcata gggactttgc ctcctgacag cagtttatgg gtgttcattg tggcacttga
7381 gttttcttgc atacttgtta gagaaaccaa gtttgtcatc aacttcttat ttaaccccct
7441 ggctataact tcatggatta tgttataatt aagccatcca gagtaaaatc tgtttagatt
7501 atcttggagt aagggggaaa aaatctgtaa ttttttctcc tcaactagat atatacataa
7561 aaaatgattg tattgcttca tttaaaaaat ataacgcaaa atctcttttc cttctaaaaa
7621 aaaaaaaaaa aaa
＜110〉Attached Tongji Hospital, Tongji Univ.
＜12〉pulmonary thromboembolism related gene and application thereof
<160>142
<210>70
<211>1935
<212>DNA
＜213〉human (Homo sapiens)
<400>70
1 atctccgctg gttcccggaa gccgccgcgg acaagctctc ccgggcgcgg gcgggggtcg
61 tgtgcttgga ggaagccgcg gaacccccag cgtccgtcca tggcgtggag ccttgggagc
121 tggctgggtg gctgcctgct ggtgtcagca ttgggaatgg taccacctcc cgaaaatgtc
181 agaatgaatt ctgttaattt caagaacatt ctacagtggg agtcacctgc ttttgccaaa
241 gggaacctga ctttcacagc tcagtaccta agttatagga tattccaaga taaatgcatg
301 aatactacct tgacggaatg tgatttctca agtctttcca agtatggtga ccacaccttg
361 agagtcaggg ctgaatttgc agatgagcat tcagactggg taaacatcac cttctgtcct
421 gtggatgaca ccattattgg accccctgga atgcaagtag aagtacttgc tgattcttta
481 catatgcgtt tcttagcccc taaaattgag aatgaatacg aaacttggac tatgaagaat
541 gtgtataact catggactta taatgtgcaa tactggaaaa acggtactga tgaaaagttt
601 caaattactc cccagtatga ctttgaggtc ctcagaaacc tggagccatg gacaacttat
661 tgtgttcaag ttcgagggtt tcttcctgat cggaacaaag ctggggaatg gagtgagcct
721 gtctgtgagc aaacaaccca tgacgaaacg gtcccctcct ggatggtggc cgtcatcctc
781 atggcctcgg tcttcatggt ctgcctggca ctcctcggct gcttcgcctt gctgtggtgc
841 gtttacaaga agacaaagta cgccttctcc cctaggaatt ctcttccaca gcacctgaaa
901 gagtttttgg gccatcctca tcataacaca cttctgtttt tctcctttcc attgtcggat
961 gagaatgatg tttttgacaa gctaagtgtc attgcagaag actctgagag cggcaagcag
1021 aatcctggtg acagctgcag cctcgggacc ccgcctgggc aggggcccca aagctaggct
1081 ctgagaagga aacacactcg gctgggcaca gtgacgtact ccatctcaca tctgcctcag
1141 tgagggatca gggcagcaaa caagggccaa gaccatctga gccagcccca catctagaac
1201 tcccagaccc tggacttagc caccagagag ctacatttta aaggctgtct tggcaaaaat
1261 actccatttg ggaactcact gccttataaa ggctttcatg atgttttcag aagttggcca
1321 ctgagagtgt aattttcagc cttttatatc actaaaataa gatcatgttt taattgtgag
1381 aaacagggcc gagcacagtg gctcacgcct gtaataccag caccttagag gtcgaggcag
1441 gcggatcact tgaggtcagg agttcaagac cagcctggcc aatatggtga aacccagtct
1501 ctactaaaaa tacaaaaatt agctaggcat gatggcgcat gcctataatc ccagctactc
1561 gagtgcctga ggcaggagaa ttgcatgaac ccgggaggag gaggaggagg ttgcagtgag
1621 ccgagatagc ggcactgcac tccagcctgg gtgacaaagt gagactccat ctcaaaaaaa
1681 aaaaaaaaaa aaattgtgag aaacagaaat acttaaaatg aggaataaga atggagatgt
1741 tacatctggt agatgtaaca ttctaccaga ttatggatgg actgatctga aaatcgacct
1801 caactcaagg gtggtcagct caatgctaca cagagcacgg acttttggat tctttgcagt
1861 actttgaatt tatttttcta cctatatatg ttttatatgc tgctggtgct ccattaaagt
1921 tttactctgt gttgc
＜110〉Attached Tongji Hospital, Tongji Univ.
＜120〉pulmonary thromboembolism related gene and application thereof
<160>142
<210>71
<211>1131
<212>DNA
＜213〉human (Homo sapiens)
<400>71
1 attcccagaa accaggaaat ttctgaaact gagttttaaa cctggcaact cttttaccat
61 ccctttgtat ttttgcagtt cctccctata ccagcttcct tacagctgtt ctgatttcct
121 gtcgtaagat tttttctttt cattttctcc agggagggta aatcaatata acctcttctc
181 tagagaggag gtggttaggt tggtcttaag cagtgttaga agatctattt tttttcaaac
241 caggtgtctg agctgggtga attccagcct ggggagagga ctttgatcac cagatgtttt
301 tttggtgtgc gtgctgtctt atggttgcgt ggcgagtttc tgcttcagat gcagagcact
361 gtccagagct tcctccagtg gacaatagca tatttgtcgc aaaggaggtg gaaggacaga
421 ttctggggac ttacgtttgt atcaagggct accacctggt aggaaagaag accctttttt
481 gcaatgcctc taaggagtgg gataacacca ctactgagtg ccgcttgggc cactgtcctg
541 atcctgtgct ggtgaatgga gagttcagtt cttcagggcc tgtgaatgta agtgacaaaa
601 tcacgtttat gtgcaatgac cactacatcc tcaagggcag caatcggagc cagtgtctag
661 aggaccacac ctgggcacct ccctttccca tctgcaaaag tagggactgt gaccctcctg
721 ggaatccagt tcatggctat tttgaaggaa ataacttcac cttaggatcc accattagtt
781 attactgtga agacaggtac tacttagtgg gcgtgcagga gcagcaatgc gttgatgggg
841 agtggagcag tgcacttcca gtctgcaagt tgatccagga agctcccaaa ccagagtgtg
901 agaaggcact tcttgccttt caggagagta agaacctctg cgaagccatg gagaacttta
961 tgcaacaatt aaaggaaagt ggcatgacaa tggaggagct aaaatattct ctggagctga
1021 agaaagctga gttgaaggca aaattgttgt aacactacag ctgagcagat gtaatagaaa
1081 taaacctatg aataaatttt cttcttggtt ctgaaaaaaa aaaaaaaaaa a
＜110〉Attached Tongji Hospital, Tongji Univ.
＜120〉pulmonary thromboembolism related gene and application thereof
<160>142
<210>72
<211>3948
<212>DNA
＜213〉human (Homo sapiens)
<400>72
1 ggcaagggac ggagaacggg gcggaggcgg agtcagggcg cccgcgcgtg ggccccgccc
61 ccttatgtag ggtataaagc ccctcccgct cacagtttcc ctagtcctcg aaggctcgga
121 agcccgtcac catgtcgtgc gagtcgtcta tggttctcgg gtactgggat attcgtgggc
181 tggcgcacgc catccgcctg ctcctggagt tcacggatac ctcttatgag gagaaacggt
241 acacgtgcgg ggaagctcct gactatgatc gaagccaatg gctggatgtg aaattcaagc
301 tagacctgga ctttcctaat ctgccctacc tcctggatgg gaagaacaag atcacccaga
361 gcaatgccat cttgcgctac atcgctcgca agcacaacat gtgtggtgag actgaagaag
421 aaaagattcg agtggacatc atagagaacc aagtaatgga tttccgcaca caactgataa
481 ggctctgtta cagctctgac cacgaaaaac tgaagcctca gtacttggaa gagctacctg
541 gacaactgaa acaattctcc atgtttctgg ggaaattctc atggtttgcc ggggaaaagc
601 tcacctttgt ggattttctc acctatgata tcttggatca gaaccgtata tttgacccca
661 agtgcctgga tgagttccca aacctgaagg ctttcatgtg ccgttttgag gctttggaga
721 aaatcgctgc ctacttacag tctgatcagt tctgcaagat gcccatcaac aacaagatgg
781 cccagtgggg caacaagcct gtatgctgag caggaggcag acttgcagag cttgttttgt
841 ttcatcctgt ccgtaagggg tcagcgctct tgctttgctc ttttcaatga atagcactta
901 tgttactggt gtccagctga gtttctcttg ggtataaagg ctaaaaggga aaaaggatat
961 gtggagaatc atcaagatat gaattgaatc gctgcgatac tggcatttcc ctactcccca
1021 actgagttca agggctgtag gttcatgccc aagccctgag agtgggtact agaaaaaacg
1081 agattgcaca gttggagaga gcaggtgtgt taaatgggac tggagtccct gtgaagactg
1141 ggtgaggata acacaagtaa aactgtggta ctgatggact taaccggagt tcggaaaccg
1201 tcctgtgtac acatgggagt ttagtgtgat aaaggcagta tttcagactg gtgggctagc
1261 caatagagtt gggacaattg cttactcatt aaaaataata gagccccact tgacactatt
1321 cactaaaatt aatctggaat ttaaggccca acattaaaca caaagctgtt gaaatattga
1381 tgaaaatgta agaatttttg tgaccacggg gtaggagaag tttctttaaa gacgtaaaaa
1441 gaaaaaaacc ataggctgct ctgcctgtgg agtagccatt ctttattctt ttacttttta
1501 aaataataac aatcacaaag gaaagatttg ccaattgaat aggatcaaat tctacaactt
1561 ttcctaaggc acccacaaat aaatgacaag tgagacaaaa agcactagta taaagattat
1621 ataaagacct ataaatcatt aagacaactg agtttttaaa aatggacaaa atccatgaac
1681 aatttataaa atagaaatat agccaaaaat gtctaaaaga tgtttatgat gtaaggaatt
1741 atcaattaca acagtgagaa accatatttc cttctatccg atgagtaaaa agtttctaaa
1801 gtgttggcaa ggcttaggaa agtgatatgc atttcctgct ggtcaagttg taaattagta
1861 tagctacttt ggaggacaat tgtaaaattt aaatcatatc ctatgaccca gcaattccat
1921 gctataaaaa ctcatccatg gccgggcttg gtggctcacg cctgtaatcc cagcactttg
1981 ggaggctgag gtgggcagat cacgaggtca agagatcgag accatcctgg ccaacatgat
2041 gaaaccccgt ttctactaaa aatacaaaaa ttagctgggc atggtggcat gtgcctatag
2101 tcccagctac tcaggaggct gaggcaggag aattgcttga acctgggagg cagaggttgc
2161 agtgagccga gatcacgcca ctgcactcca gcctggctac agggcgagac tctgtctcaa
2221 aaaaaaaaaa aaaaaaaaaa aaaaaacatt caaagagaca tatactaaga tgttcactgt
2281 ggcattgtct gtaatgacaa ataagtggaa accgtgtaaa tacctgtcaa tactatggag
2341 taccatgtgg caacggaaga atgagactga actgtgtgaa ctaacatgca aagatcccca
2401 aaacaggcca ggtgtggttg ctcacagctg taataacaac accttcagag gctgaggtga
2461 gaggatcagt tgaggccagg agtttaagac cagcctgggc aacatagtga gacccctgtc
2521 tcccaaaaat tttttttaat tagctgtgcg caattgctca tgcatagtcc cagctaccca
2581 ggaggctgag gtgggaggat cacttgagcc caggaatttg aagctgcagt gagctgtgtt
2641 cttgccactg cactccaatc tgggtgactg agcaagaccc tgtctcttaa aaaaataaaa
2701 aagatctcca agcatagaga agagtctgga gggaaacacc aaactcataa cagtcttact
2761 gcaggcaagt gggataaagg cccagactcc atggtggaag ttaaagggca tttccaagtt
2821 aaggctaaga cttgcttttc taactaagag aatgtgctca tgcattgctt gtgtagtaga
2881 aactagtttt tagaaaagaa agcaaactta agaaacactg actcctgtgg agatgacttg
2941 gcaccactct cctttcacag agcagagtct gaatagtctt cagagatagg cctgtgggcc
3001 agattgccat cccctatgga ccagaagcca aggatctctc tagtgatggt cagagggccc
3061 aaatggcagg gatacccagt gatgtcagga ggaatagtac agacagaagg tgctaagcag
3121 acaattcaac tgccatgttt tgccaccccc tgtgagcagg gattaggtgt tcaggccagt
3181 atcttgggca tgggggagcc tttggccaga agaggtataa agctcagaag tttttcagtc
3241 tgataactat tgatataatt tccatagtgt gagggagcgg tatgctctac ccttgtgtat
3301 ttaaggcagg acagagaaat tgaggatgcc cctggggcta gatcgatgat atgaccagaa
3361 atcaaaaagg gaatgcatta tttattgctg tgtaacactg ttaagagagg aggtagttaa
3421 gggatggata ggcacataga gagggaaggt ctcaggagaa gggatagaaa ggaactatgt
3481 tcacaagaac aacggcaaga cagtgcctat actgcctcta cagttaatag gaaaaacgga
3541 agaagttacc cttaagctag gatgttgctc agaagtgacc atcccaactt tggtgcgggc
3601 acaataaatc agcctaaatg tccctaattt aacccagctc attataatgt cattaaacat
3661 gacattagca ttgtggtttt agcaccccca tgggttttgc ttaggcactc atgggtaata
3721 accaagatgg agtccctttg gcaaaactta ggcatgcaca gctgtagtac cccaagaaga
3781 aaatgttact tctctcatct gggcaaaacc cacagaagac ttcccagctt ctgccacata
3841 aaagacacag aacacagacg ccttactggc aacctgcttt caagacccct gtctttgctg
3901 agagctttcc tttttcccaa taaattctac tctgccctac tcactctc
＜110〉Attached Tongji Hospital, Tongji Univ.
＜120〉pulmonary thromboembolism related gene and application thereof
<160>142
<210>73
<211>3015
<212>DNA
＜213〉human (Homo sapiens)
<400>73
1 cccttatggc gattgggcgg ctgcagagac caggactcag ttcccctgcc ctagtctgag
61 cctagtgggt gggactcagc tcagagtcag ttttccagaa gcaggtttca gtgcagagtt
121 ttcctacact tttcctgcgc tagagcagcg agcagcctgg aacagaccca ggcggaggac
181 acctgtgggg gagggagcgc ctggaggagc ttagagaccc cagccgggcg tgatctcacc
241 atgtgcggat ttgcgaggcg cgccctggag ctgctagaga tccggaagca cagccccgag
301 gtgtgcgaag ccaccaagac tgcggctctt ggagaaagcg tgagcagggg gccaccgcgg
361 tctccgcgcc tgtctgcacc ctgtcgcctg agctgcctga cagtgacaat gacatcccag
421 ttaccagtgt ccttgaattg atagtggctt ctgtttgtca gtctcatata agaactacag
481 ctcatcagga ggagatcgca gcagggtaag agacaccaac accatgttct gcacgaagct
541 caaggatctc aagatcacag gagagtgtcc tttctcctta ctggcaccag gtcaagttcc
601 taacgagtct tcagaggagg cagcaggaag ctcagagagc tgcaaagcaa ccgtgcccat
661 ctgtcaagac attcctgaga agaacataca agaaagtctt cctcaaagaa aaaccagtcg
721 gagccgagtc tatcttcaca ctttggcaga gagtatttgc aaactgattt tcccagagtt
781 tgaacggctg aatgttgcac ttcagagaac attggcaaag cacaaaataa aagaaagcag
841 gaaatctttg gaaagagaag actttgaaaa aacaattgca gagcaagcag ttgcagcagg
901 agttccagtg gaggttatca aagaatctct tggtgaagag gtttttaaaa tatgttacga
961 ggaagatgaa aacatccttg gggtggttgg aggcaccctt aaagattttt taaacagctt
1021 cagtaccctt ctgaaacaga gcagccattg ccaagaagca ggaaaaaggg gcaggcttga
1081 ggacgcctcc attctatgcc tggataagga ggatgatttt ctacatgttt actacttctt
1141 ccctaagaga accacctccc tgattcttcc cggcatcata aaggcagctg ctcacgtatt
1201 atatgaaacg gaagtggaag tgtcgttaat gcctccctgc ttccataatg attgcagcga
1261 gtttgtgaat cagccctact tgttgtactc cgttcacatg aaaagcacca agccatccct
1321 gtcccccagc aaaccccagt cctcgctggt gattcccaca tcgctattct gcaagacatt
1381 tccattccat ttcatgtttg acaaagatat gacaattctg caatttggca atggcatcag
1441 aaggctgatg aacaggagag actttcaagg aaagcctaat tttgaagaat actttgaaat
1501 tctgactcca aaaatcaacc agacgtttag cgggatcatg actatgttga atatgcagtt
1561 tgttgtacga gtgaggagat gggacaactc tgtgaagaaa tcttcaaggg ttatggacct
1621 caaaggccaa atgatctaca ttgttgaatc cagtgcaatc ttgtttttgg ggtcaccctg
1681 tgtggacaga ttagaagatt ttacaggacg agggctctac ctctcagaca tcccaattca
1741 caatgcactg agggatgtgg tcttaatagg ggaacaagcc cgagctcaag atggcctgaa
1801 gaagaggctg gggaagctga aggctaccct tgagcaagcc caccaagccc tggaggagga
1861 gaagaaaaag acagtagacc ttctgtgctc catatttccc tgtgaggttg ctcagcagct
1921 gtggcaaggg caagttgtgc aagccaagaa gttcagtaat gtcaccatgc tcttctcaga
1981 catcgttggg ttcactgcca tctgctccca gtgctcaccg ctgcaggtca tcaccatgct
2041 caatgcactg tacactcgct tcgaccagca gtgtggagag ctggatgtct acaaggtgga
2101 gaccattggc gatgcctatt gtgtagctgg gggattacac aaagagagtg atactcatgc
2161 tgttcagata gcgctgatgg ccctgaagat gatggagctc tctgatgaag ttatgtctcc
2221 ccatggagaa cctatcaaga tgcgaattgg actgcactct ggatcagttt ttgctggcgt
2281 cgttggagtt aaaatgcccc gttactgtct ttttggaaac aatgtcactc tggctaacaa
2341 atttgagtcc tgcagtgtac cacgaaaaat caatgtcagc ccaacaactt acagattact
2401 caaagactgt cctggtttcg tgtttacccc tcgatcaagg gaggaacttc caccaaactt
2461 ccctagtgaa atccccggaa tctgccattt tctggatgct taccaacaag gaacaaactc
2521 aaaaccatgc ttccaaaaga aagatgtgga agatggcaat gccaattttt taggcaaagc
2581 atcaggaata gattagcaac ctatatacct atttataagt ctttggggtt tgactcattg
2641 aagatgtgta gagcctctga aagcacttta gggattgtag atggctaaca agcagtatta
2701 aaatttcagg agccaagtca caatctttct cctgtttaac atgacaaaat gtactcactt
2761 cagtacttca gctcttcaag aaaaaaaaaa aaaccttaaa aagctacttt tgtgggagta
2821 tttctattat ataaccagca cttactacct gtactcaaaa ttcagcacct tgtacatata
2881 tcagataatt gtagtcaatt gtacaaactg atggagtcac ctgcaatctc atatcctggt
2941 ggaatgccat ggttattaaa gtgtgtttgt gatagtgtcg tcaaaaaaaa aaaaaaaaaa
3001 aaaaaaaaaa aaaaa
＜110〉Attached Tongji Hospital, Tongji Univ.
＜120〉pulmonary thromboembolism related gene and application thereof
<160>142
<210>74
<211>2245
<212>DNA
＜213〉human (Homo sapiens)
<400>74
1 agaacagctt gaagaccgtt catttttaag tgacaagaga ctcacctcca agaagcaatt
61 gtgttttcag aatgatttta ttcaagcaag caacttattt catttccttg tttgctacag
121 tttcctgtgg atgtctgact caactctatg aaaacgcctt cttcagaggt ggggatgtag
181 cttccatgta caccccaaat gcccaatact gccagatgag gtgcacattc cacccaaggt
241 gtttgctatt cagttttctt ccagcaagtt caatcaatga catggagaaa aggtttggtt
301 gcttcttgaa agatagtgtt acaggaaccc tgccaaaagt acatcgaaca ggtgcagttt
361 ctggacattc cttgaagcaa tgtggtcatc aaataagtgc ttgccatcga gacatttata
421 aaggagttga tatgagagga gtcaatttta atgtgtctaa ggttagcagt gttgaagaat
481 gccaaaaaag gtgcaccaat aacattcgct gccagttttt ttcatatgcc acgcaaacat
541 ttcacaaggc agagtaccgg aacaattgcc tattaaagta cagtcccgga ggaacaccta
601 ccgctataaa ggtgctgagt aacgtggaat ctggattctc actgaagccc tgtgcccttt
661 cagaaattgg ttgccacatg aacatcttcc agcatcttgc gttctcagat gtggatgttg
721 ccagggttct cactccagat gcttttgtgt gtcggaccat ctgcacctat caccccaact
781 gcctcttctt tacattctat acaaatgtat ggaaaatcga gtcacaaaga aatgtttgtc
841 ttcttaaaac atctgaaagt ggcacaccaa gttcctctac tcctcaagaa aacaccatat
901 ctggatatag ccttttaacc tgcaaaagaa ctttacctga accctgccat tctaaaattt
961 acccgggagt tgactttgga ggagaagaat tgaatgtgac ttttgttaaa ggagtgaatg
1021 tttgccaaga gacttgcaca aagatgattc gctgtcagtt tttcacttat tctttactcc
1081 cagaagactg taaggaagag aagtgtaagt gtttcttaag attatctatg gatggttctc
1141 caactaggat tgcgtatggg acacaaggga gctctggtta ctctttgaga ttgtgtaaca
1201 ctggggacaa ctctgtctgc acaacaaaaa caagcacacg cattgttgga ggaacaaact
1261 cttcttgggg agagtggccc tggcaggtga gcctgcaggt gaagctgaca gctcagaggc
1321 acctgtgtgg agggtcactc ataggacacc agtgggtcct cactgctgcc cactgctttg
1381 atgggcttcc cctgcaggat gtttggcgca tctatagtgg cattttaaat ctgtcagaca
1441 ttacaaaaga tacacctttc tcacaaataa aagagattat tattcaccaa aactataaag
1501 tctcagaagg gaatcatgat atcgccttga taaaactcca ggctcctttg aattacactg
1561 aattccaaaa accaatatgc ctaccttcca aaggtgacac aagcacaatt tataccaact
1621 gttgggtaac cggatggggc ttctcgaagg agaaaggtga aatccaaaat attctacaaa
1681 aggtaaatat tcctttggta acaaatgaag aatgccagaa aagatatcaa gattataaaa
1741 taacccaacg gatggtctgt gctggctata aagaaggggg aaaagatgct tgtaagggag
1801 attcaggtgg tcccttagtt tgcaaacaca acggaatgtg gcgtttggtg ggcatcacaa
1861 gctggggtga aggctgtgcc cgcagggagc aacctggtgt ctacaccaaa gtcgctgagt
1921 acatggactg gattttagag aaaacacaga gcagtgatgg aaaagctcag atgcagtcac
1981 cagcatgaga agcagtccag agtctaggca atttttacaa cctgagttca agtcaaattc
2041 tgagcctggg gggtcctcat ctgcaaagca tggagagtgg catcttcttt gcatcctaag
2101 gacgaaagac acagtgcact cagagctgct gaggacaatg tctgctgaag cccgctttca
2161 gcacgccgta accaggggct gacaatgcga ggtcgcaact gagatctcca tgactgtgtg
2221 ttgtgaaata aaatggtgaa agatc
＜110〉Attached Tongji Hospital, Tongji Univ.
＜120〉pulmonary thromboembolism related gene and application thereof
<160>142
<210>75
<211>1668
<212>DNA
＜213〉human (Homo sapiens)
<400>75
1 aaatatgttt ggataaccca gcagagccat ttaacctttg ggaacaaggc aactagcgtc
61 tggcagcagg aatccaacca gtgccctgag ttctgaggca gagaggagga cagaagaaac
121 aagaggctgg agattgtcaa attcagtatc ccagttggct cttgattctt ggtgaaacca
181 tccctcagct cctagaggga gattgttaga tcatgaaact aattaccatc cttttcctct
241 gctccaggct gctactaagt ttaacccagg aatcacagtc cgaggaaatt gactgcaatg
301 acaaggattt atttaaagct gtggatgctg ctctgaagaa atataacagt caaaaccaaa
361 gtaacaacca gtttgtattg taccgcataa ctgaagccac taagacggtt ggctctgaca
421 cgttttattc cttcaagtac gaaatcaagg agggggattg tcctgttcaa agtggcaaaa
481 cctggcagga ctgtgagtac aaggatgctg caaaagcagc cactggagaa tgcacggcaa
541 ccgtggggaa gaggagcagt acgaaattct ccgtggctac ccagacctgc cagattactc
601 cagccgaggg ccctgtggtg acagcccagt acgactgcct cggctgtgtg catcctatat
661 caacgcagag cccagacctg gagcccattc tgagacacgg cattcagtac tttaacaaca
721 acactcaaca ttcctccctc ttcatgctta atgaagtaaa acgggcccaa agacaggtgg
781 tggctggatt gaactttcga attacctact caattgtgca aacgaattgt tccaaagaga
841 attttctgtt cttaactcca gactgcaagt ccctttggaa tggtgatacc ggtgaatgta
901 cagataatgc atacatcgat attcagctac gaattgcttc cttctcacag aactgtgaca
961 tttatccagg gaaggatttt gtacaaccac ctaccaagat ttgcgtgggc tgccccagag
1021 atatacccac caacagccca gagctggagg agacactgac tcacaccatc acaaagctta
1081 atgcagagaa taacgcaact ttctatttca agattgacaa tgtgaaaaaa gcaagagtac
1141 aggtggtggc tggcaagaaa tattttattg acttcgtggc cagggaaacc acatgttcca
1201 aggaaagtaa tgaagagttg accgaaagct gtgagaccaa aaaacttggc caaagcctag
1261 attgcaacgc tgaagtttat gtggtaccct gggagaaaaa aatttaccct actgtcaact
1321 gtcaaccact gggaatgatc tcactgatga aaaggcctcc aggtttttca cctttccgat
1381 catcacgaat aggggaaata aaagaagaaa caactagtca cctaaggtcc tgcgagtaca
1441 agggtcgacc cccaaaggca ggggcagagc cagcatctga gagggaggtc tcttgaccaa
1501 tgggcagaat cttcactcca ggcacatagc cccaaccacc tctgccagca accttgagag
1561 gaaggacaag aagaaagatg ggatagaatt taaatagaga agaatgccat tttatcactc
1621 tgcctctggg tgaaataaag atcagtcttg atgttctaac tctaaaaa
＜110〉Attached Tongji Hospital, Tongji Univ.
＜120〉pulmonary thromboembolism related gene and application thereof
<160>142
<210>76
<211>1388
<212>DNA
＜213〉human (Homo sapitens)
<400>76
1 gggatcctta ttctatatct cttggtattt agtgtaaaaa ttttaaaatc tttacctagc
61 aatcttgagg aagaaacttg ataactgata atacatgaga ttgttaccta agtgaaatat
121 aatcctatat attcaacaaa ctttagagaa ataagataaa ttttaaagta aatgacttct
181 gtagttttat agatcctcca aaccaatcta gtctcagatc tcaccttcat catttctctc
241 atttcctttt ggcctaatta atcaaaatcc ttcctagaat gttcatttct ggccagtatg
301 tcttcctgaa tatgaataag aaataaaata ccatttgatg tttgaaatta tgggggtaat
361 ctcaatgacg gaaatagatg accaggaaaa gggaaacgaa tgcctgattc attatattca
421 tgaagatatc aaaggtttat aaagccaata tctgggaaag agaaaaccgt gagacttcca
481 gatcttctct ggtgaagtgt gtttcctgca acgatcacga acatgaacat caaaggatcg
541 ccatggaaag ggtccctcct gctgctgctg gtgtcaaacc tgctcctgtg ccagagcgtg
601 gcccccttgc ccatctgtcc cggcggggct gcccgatgcc aggtgaccct tcgagacctg
661 tttgaccgcg ccgtcgtcct gtcccactac atccataacc tctcctcaga aatgttcagc
721 gaattcgata aacggtatac ccatggccgg gggttcatta ccaaggccat caacagctgc
781 cacacttctt cccttgccac ccccgaagac aaggagcaag cccaacagat gaatcaaaaa
841 gactttctga gcctgatagt cagcatattg cgatcctgga atgagcctct gtatcatctg
901 gtcacggaag tacgtggtat gcaagaagcc ccggaggcta tcctatccaa agctgtagag
961 attgaggagc aaaccaaacg gcttctagag ggcatggagc tgatagtcag ccaggttcat
1021 cctgaaacca aagaaaatga gatctaccct gtctggtcgg gacttccatc cctgcagatg
1081 gctgatgaag agtctcgcct ttctgcttat tataacctgc tccactgcct acgcagggat
1141 tcacataaaa tcgacaatta tctcaagctc ctgaagtgcc gaatcatcca caacaacaac
1201 tgctaagccc acatccattt catctatttc tgagaaggtc cttaatgatc cgttccattg
1261 caagcttctt ttagttgtat ctcttttgaa tccatgcttg ggtgtaacag gtctcctctt
1321 aaaaaataaa aactgactcc ttagagacat caaaatccaa aaaaaaaaaa aaaaaaaaaa
1381 aaaaaaaa
＜110〉Attached Tongji Hospital, Tongji Univ.
＜120〉pulmonary thromboembolism related gene and application thereof
<160>142
<210>77
<211>1822
<212>DNA
＜213〉human (Homo sapiens)
<400>77
1 ttgccagaca gcatagaggc tgaggctggg gccaggaccc agacagagac acacggtcac
61 tgcagctgaa gccgctgccc ctgctacagg caccaccagg accagctgat cattccagcc
121 cacagcaatg gagccacatg actcctccca catggactct gagttccgat acactctctt
181 cccgattgtt tacagcatca tctttgtgct cggggtcatt gctaatggct acgtgctgtg
241 ggtctttgcc cgcctgtacc cttgcaagaa attcaatgag ataaagatct tcatggtgaa
301 cctcaccatg gcggacatgc tcttcttgat caccctgcca ctttggattg tctactacca
361 aaaccagggc aactggatac tccccaaatt cctgtgcaac gtggctggct gccttttctt
421 catcaacacc tactgctctg tggccttcct gggcgtcatc acttataacc gcttccaggc
481 agtaactcgg cccatcaaga ctgctcaggc caacacccgc aagcgtggca tctctttgtc
541 cttggtcatc tgggtggcca ttgtgggagc tgcatcctac ttcctcatcc tggactccac
601 caacacagtg cccgacagtg ctggctcagg caacgtcact cgctgctttg agcattacga
661 gaagggcagc gtgccagtcc tcatcatcca catcttcatc gtgttcagct tcttcctggt
721 cttcctcatc atcctcttct gcaacctggt catcatccgt accttgctca tgcagccggt
781 gcagcagcag cgcaacgctg aagtcaagcg ccgggcgctg tggatggtgt gcacggtctt
841 ggcggtgttc atcatctgct tcgtgcccca ccacgtggtg cagctgccct ggacccttgc
901 tgagctgggc ttccaggaca gcaaattcca ccaggccatt aatgatgcac atcaggtcac
961 cctctgcctc cttagcacca actgtgtctt agaccctgtt atctactgtt tcctcaccaa
1021 gaagttccgc aagcacctca ccgaaaagtt ctacagcatg cgcagtagcc ggaaatgctc
1081 ccgggccacc acggatacgg tcactgaagt ggttgtgcca ttcaaccaga tccctggcaa
1141 ttccctcaaa aattagtccc tgcttccagg cctgaagtct tctcctccat gaacatcatg
1201 gactgagctg ggggaagaag ggatatctac tgtggtctgg gcaccacctc tgtgggcact
1261 ggtgggccat tagatttgga ggctacctca cctgggcagg gatgatggca gagccaggct
1321 gttggaaaat ccagaactca aatgagcccc ttcatccgcc tgtgggcgca tactacagta
1381 actgtgactg atgactttat cctgagtccc ttaatcttat ggggccggaa ggaatgtcag
1441 ggccaggtgc agaccttggg ggaagacttt aaaccaccta gttctccccg atggggcatc
1501 ggtctaaagc tttgggggag tgggcgcagt ggctcacacc tgtaatccca gcactttggg
1561 aggccgaggt gggcagatca tgggtcaaga gatcgagacc atcctggcca acattgtaaa
1621 accccatctc tactaaaaca tacaaaaatt agccgggcat ggtggcacac gcctgtagtc
1681 ccagctactc aggaggctga ggcaggagaa tcgcttgaac ctgggaggca gaggttgcag
1741 tgaacctaga ttgcaccatt gcactctagc ctggcaacag agcgagattc catctcaaaa
1801 aaaaaaaaaa aaaaaaaaaa aa
＜110〉Attached Tongji Hospital, Tongji Univ.
＜120〉pulmonary thromboembolism related gene and application thereof
<160>142
<210>78
<211>2103
<212>DNA
＜213〉human (Homo sapiens)
<400>78
1 aagctgacac acagaccgac acaggcagcg agagacacga ggagcaaagc aagtgaaggc
61 acagacgcac gggacaggag agcctgggca agactggaga gcccagacct gggatggcgg
121 attcgtgcag gaacctcacc tacgtgcggg gctcggtggg gccggccacc agcaccctga
181 tgttcgtggc cggtgtggtg ggcaacgggc tggccctggg catcctgagc gcacggcgac
241 cggcgcgccc ctcggccttc gcggtgctgg tgaccggact ggcggccacc gacctgctgg
301 gcaccagctt cctgagcccg gccgtgttcg tggcctatgc gcgcaacagc tccctgctgg
361 gcctggcccg aggcggcccc gccctgtgcg atgccttcgc cttcgccatg accttcttcg
421 gcctggcgtc catgctcatc ctctttgcca tggccgtgga gcgctgcctg gcgctgagcc
481 acccctacct ctacgcgcag ctggacgggc cccgctgcgc ccgcctggcg ctgccagcca
541 tctacgcctt ctgcgtcctc ttctgcgcgc tgcccctgct gggcctgggc caacaccagc
601 agtactgccc cggcagctgg tgcttcctcc gcatgcgctg ggcccagccg ggcggcgccg
661 ccttctcgct ggcctacgcc ggcctggtgg ccctgctggt ggctgccatc ttcctctgca
721 acggctcggt caccctcagc ctctgccgca tgtaccgcca gcagaagcgc caccagggct
781 ctctgggtcc acggccgcgc accggagagg acgaggtgga ccacctgatc ctgctggccc
841 tcatgacagt ggtcatggcc gtgtgctccc tgcctctcac gatccgctgc ttcacccagg
901 ctgtcgcccc tgacagcagc agtgagatgg gggacctcct tgccttccgc ttctacgcct
961 tcaaccccat cctggacccc tgggtcttca tccttttccg caaggctgtc ttccagcgac
1021 tcaagctctg ggtctgctgc ctgtgcctcg ggcctgccca cggagactcg cagacacccc
1081 tttcccagct cgcctcaggg aggagggacc caagggcccc ctctgctcct gtgggaaagg
1141 aggggagctg cgtgcctttg tcggcttggg gcgaggggca ggtggagccc ttgcctccca
1201 cacagcagtc cagcggcagc gccgtgggaa cgtcgtccaa agcagaagcc agcgtcgcct
1261 gctccctctg ctgacatttc aagctgaccc tgtgatctct gccctgtctt cgggcgacag
1321 gagccagaaa atcagggaca tggctgatgg ctgcggatgc tggaaccttg gcccccaaac
1381 tctggggccg atcagctgct gtttctcctg cggcagggca gtcgctgctg gctctgggaa
1441 gagagtgagg gacagaggaa acgtttatcc tggagtgcag aaagaatggt tctctcaaaa
1501 taaccagtgg cctggccgac ctgctctggc cctggattcc ccatccatct cattgtctaa
1561 atatttagaa ggcggagaag ttcccagagg cttctgtaca gtcaggtctg ctctggtctg
1621 ggtgctggct ccaatctgcg tccacttagg aggcccaact gcccacccca agtccccagg
1681 ggatggccct ccccctctac caagccactc caagagccag cccctttctg ctccacaaaa
1741 accacagtta ttggaaaagc tccctgcctt cccttgccgc tggtccccca ccaggcttgg
1801 gagccctggc atcccaaagg ggcaacggga ggaaggggag gctgctgcat tgtgggtgat
1861 gacgtaggac atgtgcttgg tacaaaaagg gcctgagaca ttccacctag cttgactggc
1921 tgcaagatga gaactggggg ggtgcaggtg gtggggagac agatggagaa gctggcagat
1981 gaagggtggg ggctgcggat cccagggact gccccagaac acaaacctaa gtcctgtgcc
2041 tgtccccagg gtcctgaata aataaaagcc tccttgcaga gcctgaaaaa aaaaaaaaaa
2101 aaa
＜110〉Attached Tongji Hospital, Tongji Univ.
＜120〉pulmonary thromboembolism related gene and application thereof
<160>142
<210>79
<211>1630
<212>DNA
＜213〉human (Homo sapiens)
<400>79
1 agggccgggg tggggcgctg gcgtttccgt tgcttggatc agtctaggtg cagctgcgga
61 tccttcagcg tctgcatctc ggcgtcgccc cgcgtaccgt cgcccggctc tccgccgctc
121 tcccgggggt tcggggcact tgggtcccac agtctggtcc tgcttcacct tcccctgacc
181 tgagtagtcg ccatggcaca ggttctcaga ggcactgtga ctgacttccc tggatttgat
241 gagcgggctg atgcagaaac tcttcggaag gctatgaaag gcttgggcac agatgaggag
301 agcatcctga ctctgttgac atcccgaagt aatgctcagc gccaggaaat ctctgcagct
361 tttaagactc tgtttggcag ggatcttctg gatgacctga aatcagaact aactggaaaa
421 tttgaaaaat taattgtggc tctgatgaaa ccctctcggc tttatgatgc ttatgaactg
481 aaacatgcct tgaagggagc tggaacaaat gaaaaagtac tgacagaaat tattgcttca
541 aggacacctg aagaactgag agccatcaaa caagtttatg aagaagaata tggctcaagc
601 ctggaagatg acgtggtggg ggacacttca gggtactacc agcggatgtt ggtggttctc
661 cttcaggcta acagagaccc tgatgctgga attgatgaag ctcaagttga acaagatgct
721 caggctttat ttcaggctgg agaacttaaa tgggggacag atgaagaaaa gtttatcacc
781 atctttggaa cacgaagtgt gtctcatttg agaaaggtgt ttgacaagta catgactata
841 tcaggatttc aaattgagga aaccattgac cgcgagactt ctggcaattt agagcaacta
901 ctccttgctg ttgtgaaatc tattcgaagt atacctgcct accttgcaga gaccctctat
961 tatgctatga agggagctgg gacagatgat cataccctca tcagagtcat ggtttccagg
1021 agtgagattg atctgtttaa catcaggaag gagtttagga agaattttgc cacctctctt
1081 tattccatga ttaagggaga tacatctggg gactataaga aagctcttct gctgctctgt
1141 ggagaagatg actaacgtgt cacggggaag agctccctgc tgtgtgcctg caccacccca
1201 ctgccttcct tcagcacctt tagctgcatt tgtatgccag tgcttaacac attgccttat
1261 tcatactagc atgctcatga ccaacacata cacgtcatag aagaaaatag tggtgcttct
1321 ttctgatctc tagtggagat ctctttgact gctgtagtac taaagtgtac ttaatgttac
1381 taagtttaat gcctggccat tttccattta tatatatttt ttaagaggct agagtgcttt
1441 tagccttttt taaaaactcc atttatatta catttgtaac catgatactt taattagaag
1501 cttagccttg aaattgtgaa ctcttggaaa tgttattagt gaagttcgca actaaactaa
1561 acctgtaaaa ttatgatgat tgtattcaaa agattaatga aaaataaaca tttctgtccc
1621 cctgaattat
＜110〉Attached Tongji Hospital, Tongji Univ.
＜120〉pulmonary thromboembolism related gene and application thereof
<160>142
<210>80
<211>1981
<212>DNA
＜213〉human (Homo sapiens)
<400>80
1 cacggggcgg gcggacgctg gcgcgggtag gtaagagcag cggcgggcgg tggcgctcac
61 tcccggcttc caaccgcgcg gagcctctgc cttggagatt ctcagtgctg cggatcatgt
121 ccctaagggg cagcctctcg cgtctcctcc agacgcgagt gcattccatc ctgaagaaat
181 ccgtccactc cgtggctgtg ataggagccc cgttctcaca agggcagaaa agaaaaggag
241 tggagcatgg tcccgctgcc ataagagaag ctggcttgat gaaaaggctc tccagtttgg
301 gctgccacct aaaagacttt ggagatttga gttttactcc agtccccaaa gatgatctct
361 acaacaacct gatagtgaat ccacgctcag tgggtcttgc caaccaggaa ctggctgagg
421 tggttagcag agctgtgtca gatggctaca gctgtgtcac actgggagga gaccacagcc
481 tggcaatcgg taccattagt ggccatgccc gacactgccc agacctttgt gttgtctggg
541 ttgatgccca tgctgacatc aacacacccc ttaccacttc atcaggaaat ctccatggac
601 agccagtttc atttctcctc agagaactac aggataaggt accacaactc ccaggatttt
661 cctggatcaa accttgtatc tcttctgcaa gtattgtgta tattggtctg agagacgtgg
721 accctcctga acattttatt ttaaagaact atgatatcca gtatttttcc atgagagata
781 ttgatcgact tggtatccag aaggtcatgg aacgaacatt tgatctgctg attggcaaga
841 gacaaagacc aatccatttg agttttgata ttgatgcatt tgaccctaca ctggctccag
901 ccacaggaac tcctgttgtc gggggactaa cctatcgaga aggcatgtat attgctgagg
961 aaatacacaa tacagggttg ctatcagcac tggatcttgt tgaagtcaat cctcagttgg
1021 ccacctcaga ggaagaggcg aagactacag ctaacctggc agtagatgtg attgcttcaa
1081 gctttggtca gacaagagaa ggagggcata ttgtctatga ccaacttcct actcccagtt
1141 caccagatga atcagaaaat caagcacgtg tgagaattta ggagacactg tgcactgaca
1201 tgtttcacaa caggcattcc agaattatga ggcattgagg ggatagatga atactaaatg
1261 gttgtctggg tcaatactgc cttaatgaga acatttacac attctcacaa ttgtaaagtt
1321 tcccctctat tttggtgacc aatactactg taaatgtatt tggttttttg cagttcacag
1381 ggtattaata tgctacagta ctatgtaaat ttaaagaagt cataaacagc atttattacc
1441 ttggtatatc atactggtct tgttgctgtt gttccttcac atttaagtgg tttttcatct
1501 ttcctccctc ctcccacagc ctggctatac agtgcatcct tgaactgtca gcccacagca
1561 gcaatatgct tattctatcc acatccctaa catcatgcat tcacaaggtc aaagttctgg
1621 tccacaaacc cttccctata gaagttcaat ggctgcgaaa gaatttgtag taaaccaggc
1681 ctcccaggat ggcgagctcc agtaagatga taatggaaag cagcagcttg ttggttgtca
1741 ctctacaaag agaagcaaag tggggagtag tcagaagttt ggataacctt ccttctaaac
1801 attttggggt tagacctggg accacggctg gatactctga ggctgtatgt ttgatcacac
1861 agccacttag caggaagtac tcataaggtt ctttagctgt cacttaggga taacactgtc
1921 tacctcacag aaatgttaaa ctgagacaat aaaaaccaaa gcataaaaat ggattctgaa
1981 a
＜110〉Attached Tongji Hospital, Tongji Univ.
＜120〉pulmonary thromboembolism related gene and application thereof
<160>142
<210>81
<211>1177
<212>DNA
＜213〉human (Homo sapiens)
<400>81
1 gccaaggctg gggcagggga gtcagcagag gcctcgctcg ggcgcccagt ggtcctgccg
61 cctggtctca cctcgctatg gttcgtctgc ctctgcagtg cgtcctctgg ggctgcttgc
121 tgaccgctgt ccatccagaa ccacccactg catgcagaga aaaacagtac ctaataaaca
181 gtcagtgctg ttctttgtgc cagccaggac agaaactggt gagtgactgc acagagttca
241 ctgaaacgga atgccttcct tgcggtgaaa gcgaattcct agacacctgg aacagagaga
301 cacactgcca ccagcacaaa tactgcgacc ccaacctagg gcttcgggtc cagcagaagg
361 gcacctcaga aacagacacc atctgcacct gtgaagaagg ctggcactgt acgagtgagg
421 cctgtgagag ctgtgtcctg caccgctcat gctcgcccgg ctttggggtc aagcagattg
481 ctacaggggt ttctgatacc atctgcgagc cctgcccagt cggcttcttc tccaatgtgt
541 catctgcttt cgaaaaatgt cacccttgga caagctgtga gaccaaagac ctggttgtgc
601 aacaggcagg cacaaacaag actgatgttg tctgtggtcc ccaggatcgg ctgagagccc
661 tggtggtgat ccccatcatc ttcgggatcc tgtttgccat cctcttggtg ctggtcttta
721 tcaaaaaggt ggccaagaag ccaaccaata aggcccccca ccccaagcag gaaccccagg
781 agatcaattt tcccgacgat cttcctggct ccaacactgc tgctccagtg caggagactt
841 tacatggatg ccaaccggtc acccaggagg atggcaaaga gagtcgcatc tcagtgcagg
901 agagacagtg aggctgcacc cacccaggag tgtggccacg tgggcaaaca ggcagttggc
961 cagagagcct ggtgctgctg ctgctgtggc gtgagggtga ggggctggca ctgactgggc
1021 atagctcccc gcttctgcct gcacccctgc agtttgagac aggagacctg gcactggatg
1081 cagaaacagt tcaccttgaa gaacctctca cttcaccctg gagcccatcc agtctcccaa
1141 cttgtattaa agacagaggc agaaaaaaaa aaaaaaa
＜110〉Attached Tongji Hospital, Tongji Univ.
＜120〉pulmonary thromboembolism related gene and application thereof
<160>142
<210>82
<211>2094
<212>DNA
＜213〉human (Homo sapiens)
<400>82
1 gcttgttccc tgtcctctgg ccctttgcaa ataaatgcct taccagacct gccctgccac
61 cccactcgca gccacccagc aagagcagca tgtcagcctg ccggagcttt gcagttgcaa
121 tctgcatttt agaaataagc atcctcacag cacagtacac gaccagttat gacccagagc
181 taacagaaag cagtggctct gcatcacaca tagactgcag aatgagcccc tggagtgaat
241 ggtcacaatg cgatccttgt ctcagacaaa tgtttcgttc aagaagcatt gaggtatttg
301 gacaatttaa tgggaaaaga tgcaccgacg ctgtgggaga cagacgacag tgtgtgccca
361 cagagccctg tgaggatgct gaggatgact gcggaaatga ctttcaatgc agtacaggca
421 gatgcataaa gatgcgactt cggtgtaatg gtgacaatga ctgcggagac ttttcagatg
481 aggatgattg tgaaagtgag ccccgtcccc cctgcagaga cagagtggta gaagagtctg
541 agctggcacg aacagcaggc tatgggatca acattttagg gatggatccc ctaagcacac
601 cttttgacaa tgagttctac aatggactct gtaaccggga tcgggatgga aacactctga
661 catactaccg aagaccttgg aacgtggctt ctttgatcta tgaaaccaaa ggcgagaaaa
721 atttcagaac cgaacattac gaagaacaaa ttgaagcatt taaaagtatc atccaagaga
781 agacatcaaa ttttaatgca gctatatctc taaaatttac acccactgaa acaaataaag
841 ctgaacaatg ttgtgaggaa acagcctcct caatttcttt acatggcaag ggtagttttc
901 ggttttcata ttccaaaaat gaaacttacc aactattttt gtcatattct tcaaagaagg
961 aaaaaatgtt tctgcatgtg aaaggagaaa ttcatctggg aagatttgta atgagaaatc
1021 gcgatgttgt gctcacaaca acttttgtgg atgatataaa agctttgcca actacctatg
1081 aaaagggaga atattttgcc tttttggaaa cctatggaac tcactacagt agctctgggt
1141 ctctaggagg actctatgaa ctaatatatg ttttggataa agcttccatg aagcggaaag
1201 gtgttgaact aaaagacata aagagatgcc ttgggtatca tctggatgta tctctggctt
1261 tctctgaaat ctctgttgga gctgaattta ataaagatga ttgtgtaaag aggggagagg
1321 gtagagctgt aaacatcacc agtgaaaacc tcatagatga tgttgtttca ctcataagag
1381 gtggaaccag aaaatatgca tttgaactga aagaaaagct tctccgagga accgtgattg
1441 atgtgactga ctttgtcaac tgggcctctt ccataaatga tgctcctgtt ctcattagtc
1501 aaaaactgtc tcctatatat aatctggttc cagtgaaaat gaaaaatgca cacctaaaga
1561 aacaaaactt ggaaagagcc attgaagact atatcaatga atttagtgta agaaaatgcc
1621 acacatgcca aaatggaggt acagtgattc taatggatgg aaagtgtttg tgtgcctgcc
1681 cattcaaatt tgagggaatt gcctgtgaaa tcagtaaaca aaaaatttct gaaggattgc
1741 cagccctaga gttccccaat gaaaaataga gctgttggct tctctgagct ccagtggaag
1801 aagaaaacac tagtaccttc agatcctacc cctgaagata atcttagctg ccaagtaaat
1861 agcaacatgc ttcatgaaaa tcctaccaac ctctgaagtc tcttctctct taggtctata
1921 attttttttt taatttttct tccttaaact cctgtgatgt ttccattttt tgttccctaa
1981 tgagaagtca acagtgaaat acgccagaac tgctttatcc cacggaaaat gccaatctct
2041 tctaaaaaaa aacaaaatta aactaaaaaa aaaaaaaaaa aaaaaaaaaa aaaa
＜110〉Attached Tongji Hospital, Tongji Univ.
＜120〉pulmonary thromboembolism related gene and application thereof
<160>142
<210>83
<211>1246
<212>DNA
＜213〉human (Homo sapiens)
<400>83
1 gaccagccta cagccgcctg catctgtatc cagcgccagg tcccgccagt cccagctgcg
61 cgcgcccccc agtcccgcac ccgttcggcc caggctaagt tagccctcac catgccggtc
121 aaaggaggca ccaagtgcat caaatacctg ctgttcggat ttaacttcat cttctggctt
181 gccgggattg ctgtccttgc cattggacta tggctccgat tcgactctca gaccaagagc
241 atcttcgagc aagaaactaa taataataat tccagcttct acacaggagt ctatattctg
301 atcggagccg gcgccctcat gatgctggtg ggcttcctgg gctgctgcgg ggctgtgcag
361 gagtcccagt gcatgctggg actgttcttc ggcttcctct tggtgatatt cgccattgaa
421 atagctgcgg ccatctgggg atattcccac aaggatgagg tgattaagga agtccaggag
481 ttttacaagg acacctacaa caagctgaaa accaaggatg agccccagcg ggaaacgctg
541 aaagccatcc actatgcgtt gaactgctgt ggtttggctg ggggcgtgga acagtttatc
601 tcagacatct gccccaagaa ggacgtactc gaaaccttca ccgtgaagtc ctgtcctgat
661 gccatcaaag aggtcttcga caataaattc cacatcatcg gcgcagtggg catcggcatt
721 gccgtggtca tgatatttgg catgatcttc agtatgatct tgtgctgtgc tatccgcagg
781 aaccgcgaga tggtctagag tcagcttaca tccctgagca ggaaagttta cccatgaaga
841 ttggtgggat tttttgtttg tttgttttgt tttgtttgtt gtttgttgtt tgtttttttg
901 ccactaattt tagtattcat tctgcattgc tagataaaag ctgaagttac tttatgtttg
961 tcttttaatg cttcattcaa tattgacatt tgtagttgag cggggggttt ggtttgcttt
1021 ggtttatatt ttttcagttg tttgtttttg cttgttatat taagcagaaa tcctgcaatg
1081 aaaggtacta tatttgctag actctagaca agatattgta cataaaagaa tttttttgtc
1141 tttaaataga tacaaatgtc tatcaacttt aatcaagttg taacttatat tgaagacaat
1201 ttgatacata ataaaaaatt atgacaatgt caaaaaaaaa aaaaaa
＜110〉Attached Tongji Hospital, Tongji Univ.
＜120〉pulmonary thromboembolism related gene and application thereof
<160>142
<210>84
<211>1959
<212>DNA
＜213〉human (Homo sapiens)
<400>84
1 tctcacggag acggaccaca gcaagcagag gctggggggg ggaaagacga ggaaagagga
61 ggaaaacaaa agctgctact tatggaagat acaaaggagt ctaacgtgaa gacattttgc
121 tccaagaata tcctagccat ccttggcttc tcctctatca tagctgtgat agctttgctt
181 gctgtggggt tgacccagaa caaagcattg ccagaaaacg ttaagtatgg gattgtgctg
241 gatgcgggtt cttctcacac aagtttatac atctataagt ggccagcaga aaaggagaat
301 gacacaggcg tggtgcatca agtagaagaa tgcagggtta aaggtcctgg aatctcaaaa
361 tttgttcaga aagtaaatga aataggcatt tacctgactg attgcatgga aagagctagg
421 gaagtgattc caaggtccca gcaccaagag acacccgttt acctgggagc cacggcaggc
481 atgcggttgc tcaggatgga aagtgaagag ttggcagaca gggttctgga tgtggtggag
541 aggagcctca gcaactaccc ctttgacttc cagggtgcca ggatcattac tggccaagag
601 gaaggtgcct atggctggat tactatcaac tatctgctgg gcaaattcag tcagaaaaca
661 aggtggttca gcatagtccc atatgaaacc aataatcagg aaacctttgg agctttggac
721 cttgggggag cctctacaca agtcactttt gtaccccaaa accagactat cgagtcccca
781 gataatgctc tgcaatttcg cctctatggc aaggactaca atgtctacac acatagcttc
841 ttgtgctatg ggaaggatca ggcactctgg cagaaactgg ccaaggacat tcaggttgca
901 agtaatgaaa ttctcaggga cccatgcttt catcctggat ataagaaggt agtgaacgta
961 agtgaccttt acaagacccc ctgcaccaag agatttgaga tgactcttcc attccagcag
1021 tttgaaatcc agggtattgg aaactatcaa caatgccatc aaagcatcct ggagctcttc
1081 aacaccagtt actgccctta ctcccagtgt gccttcaatg ggattttctt gccaccactc
1141 cagggggatt ttggggcatt ttcagctttt tactttgtga tgaagttttt aaacttgaca
1201 tcagagaaag tctctcagga aaaggtgact gagatgatga aaaagttctg tgctcagcct
1261 tgggaggaga taaaaacatc ttacgctgga gtaaaggaga agtacctgag tgaatactgc
1321 ttttctggta cctacattct ctccctcctt ctgcaaggct atcatttcac agctgattcc
1381 tgggagcaca tccatttcat tggcaagatc cagggcagcg acgccggctg gactttgggc
1441 tacatgctga acctgaccaa catgatccca gctgagcaac cattgtccac acctctctcc
1501 cactccacct atgtcttcct catggttcta ttctccctgg tccttttcac agtggccatc
1561 ataggcttgc ttatctttca caagccttca tatttctgga aagatatggt atagcaaaag
1621 cagctgaaat atgctggctg gagtgaggaa aaaaatcgtc cagggagcat tttcctccat
1681 cgcagtgttc aaggccatcc ttccctgtct gccagggcca gtcttgacga gtgtgaagct
1741 tccttggctt ttactgaagc ctttcttttg gaggtattca atatcctttg cctcaaggac
1801 ttcggcagat actgtctctt tcatgagttt ttcccagcta cacctttctc ctttgtactt
1861 tgtgcttgta taggttttaa agacctgaca cctttcataa tctttgcttt ataaaagaac
1921 aatattgact ttgtctagaa aaaaaaaaaa aaaaaaaaa
＜110〉Attached Tongji Hospital, Tongji Univ.
＜120〉pulmonary thromboembolism related gene and application thereof
<160>142
<210>85
<211>2153
<212>DNA
＜213〉human (Homo sapiens)
<400>85
1 aagactgcga gctccccgca ccccctcgca ctccctctgg ccggcccagg gcgccttcag
61 cccaacctcc ccagccccac gggcgccacg gaacccgctc gatctcgccg ccaactggta
121 gacatggaga cccctgcctg gccccgggtc ccgcgccccg agaccgccgt cgctcggacg
181 ctcctgctcg gctgggtctt cgcccaggtg gccggcgctt caggcactac aaatactgtg
241 gcagcatata atttaacttg gaaatcaact aatttcaaga caattttgga gtgggaaccc
301 aaacccgtca atcaagtcta cactgttcaa ataagcacta agtcaggaga ttggaaaagc
361 aaatgctttt acacaacaga cacagagtgt gacctcaccg acgagattgt gaaggatgtg
421 aagcagacgt acttggcacg ggtcttctcc tacccggcag ggaatgtgga gagcaccggt
481 tctgctgggg agcctctgta tgagaactcc ccagagttca caccttacct ggagacaaac
541 ctcggacagc caacaattca gagttttgaa caggtgggaa caaaagtgaa tgtgaccgta
601 gaagatgaac ggactttagt cagaaggaac aacactttcc taagcctccg ggatgttttt
661 ggcaaggact taatttatac actttattat tggaaatctt caagttcagg aaagaaaaca
721 gccaaaacaa acactaatga gtttttgatt gatgtggata aaggagaaaa ctactgtttc
781 agtgttcaag cagtgattcc ctcccgaaca gttaaccgga agagtacaga cagcccggta
841 gagtgtatgg gccaggagaa aggggaattc agagaaatat tctacatcat tggagctgtg
901 gtatttgtgg tcatcatcct tgtcatcatc ctggctatat ctctacacaa gtgtagaaag
961 gcaggagtgg ggcagagctg gaaggagaac tccccactga atgtttcata aaggaagcac
1021 tgttggagct actgcaaatg ctatattgca ctgtgaccga gaacttttaa gaggatagaa
1081 tacatggaaa cgcaaatgag tatttcggag catgaagacc ctggagttca aaaaactctt
1141 gatatgacct gttattacca ttagcattct ggttttgaca tcagcattag tcactttgaa
1201 atgtaacgaa tggtactaca accaattcca agttttaatt tttaacacca tggcaccttt
1261 tgcacataac atgctttaga ttatatattc cgcacttaag gattaaccag gtcgtccaag
1321 caaaaacaaa tgggaaaatg tcttaaaaaa tcctgggtgg acttttgaaa agcttttttt
1381 tttttttttt tttgagacgg agtcttgctc tgttgcccag gctggagtgc agtagcacga
1441 tctcggctca cttgcaccct ccgtctctcg ggttcaagca attgtctgcc tcagcctccc
1501 gagtagctgg gattacaggt gcgcactacc acgccaagct aatttttgta ttttttagta
1561 gagatggggt ttcaccatct tggccaggct ggtcttgaat tcctgacctc agtgatccac
1621 ccaccttggc ctcccaaaga tgctagtatt atgggcgtga accaccatgc ccagccgaaa
1681 agcttttgag gggctgactt caatccatgt aggaaagtaa aatggaagga aattgggtgc
1741 atttctagga cttttctaac atatgtctat aatatagtgt ttaggttctt ttttttttca
1801 ggaatacatt tggaaattca aaacaattgg gcaaactttg tattaatgtg ttaagtgcag
1861 gagacattgg tattctgggc agcttcctaa tatgctttac aatctgcact ttaactgact
1921 taagtggcat taaacatttg agagctaact atatttttat aagactacta tacaaactac
1981 agagtttatg atttaaggta cttaaagctt ctatggttga cattgtatat ataatttttt
2041 aaaaaggttt ttctatatgg ggattttcta tttatgtagg taatattgtt ctatttgtat
2101 atattgagat aatttattta atatacttta aataaaggtg actgggaatt gtt
＜110〉Attached Tongji Hospital, Tongji Univ.
＜120〉pulmonary thromboembolism related gene and application thereof
<160>142
<210>86
<211>2208
<212>DNA
＜213〉human (Homo sapiens)
<400>86
1 cttattgata acctcagacg ttcccaccac tgaagatgag gttgaaaaac ctgactttta
61 tcatcatatt gataatctca ggagagctct atgcagaaga gaaaccctgt ggttttcctc
121 atgtggaaaa tggaagaatt gcccaatatt actatacttt taaaagcttt tactttccaa
181 tgagcataga caaaaaattg tcatttttct gcttggctgg ttataccact gaaagtggaa
241 gacaagaaga gcaaaccacg tgtacaacag aaggctggtc tccagagcca aggtgcttca
301 aaaaatgcac taagcctgac ctgagtaatg gttacatctc tgatgtaaag ttattgtata
361 aaattcaaga gaacatgcat tatggttgcg cttcagggta caaaaccact ggagggaagg
421 atgaagaagt ggttcaatgt ctctctgatg gatggtcttc tcaaccaacc tgtaggaaag
481 aacatgaaac gtgtttggct cctgaattat ataatggaaa ttattccaca acacagaaaa
541 cattcaaagt gaaggacaaa gtacaatacg aatgtgctac tggctactac acagctggag
601 gaaagaagac agaggaggta gaatgtctca catacggatg gtctctcaca ccaaaatgta
661 ccaaattaaa gtgctcttct ttaagattaa ttgaaaatgg ttattttcat cctgtaaagc
721 aaacctatga agaaggagat gtcgttcagt ttttctgtca tgaaaattat tatctaagtg
781 gatctgattt aattcaatgc tataactttg gttggtaccc agaatctcct gtatgcgaag
841 gaagaagaaa cagatgtcct cctccacctc tgcccataaa ctccaaaatt caaacacatt
901 caacaactta tcgtcatgga gaaatagttc atatagaatg tgaacttaat tttgagatcc
961 atgggtcagc agaaatacgt tgtgaagatg gaaaatggac agaacctcca aaatgcattg
1021 aaggacagga gaaggtagcc tgtgaggaac cacccttcat tgaaaatggt gcagcaaatt
1081 tacactctaa gatttattac aatggggata aagtgacata tgcatgtaaa agcggctacc
1141 ttctccatgg atcgaatgag ataacttgta atcgtggaaa atggacactt cctcctgagt
1201 gtgttgaaaa taatgagaat tgtaagcatc ctcctgttgt aatgaatggg gctgttgcag
1261 acgggatatt ggcaagctat gcaacaggat cctcagtgga atatagatgc aatgaatatt
1321 acttactgag gggatcaaaa atatctcgtt gcgaacaagg aaaatggtca tccccacctg
1381 tttgcttgga accatgtact gttaatgtgg attacatgaa cagaaataac atagaaatga
1441 agtggaaata tgaagggaaa gtcttacatg gagatttaat agattttgta tgtaaacagg
1501 gatatgactt atctccatta accccattgt ctgaattatc tgtgcagtgc aacagaggag
1561 aagtgaaata tcctttatgt actagaaaag aatctaaagg aatgtgcaca tctcctcctc
1621 ttattaaaca tggagtcatt attagttcaa cagtagacac ctatgaaaat ggctcttcag
1681 tagaatacag atgttttgat caccatttcc tagaaggatc tagggaggcc tattgtttag
1741 atggaatgtg gactacacca ccattgtgtt tagagccatg cacattatct tttactgaaa
1801 tggaaaagaa taatttactt ctgaaatggg attttgacaa cagaccacac attttgcatg
1861 gtgaatatat tgagtttatt tgtagaggag atacttatcc agctgaatta tatattactg
1921 gatctatact tagaatgcaa tgtgacagag ggcagttaaa atatccaaga tgtattccaa
1981 gacaaagcac tctgtcttat caagaacgct taagaacata gaaatgaatg gcagaaagag
2041 gagtcatatt tcaatacatc atgaaattcc ttataaaata taattttgag gaaataagtt
2101 aaaaacttcg gagtttttcc ttgcttaaat atttgaatct aaattatttg tgctgaacat
2161 ttcattattt ataaatgaaa accaataaat gtctaatttt tagtttgt
＜110〉Attached Tongji Hospital, Tongji Univ.
＜120〉pulmonary thromboembolism related gene and application thereof
<160>142
<210>87
<211>5361
<212>DNA
＜213〉human (Homo sapiens)
<400>87
1 ctgcaaaccc agcgcaacta cggtcccccg gtcagaccca ggatggggcc agaacggaca
61 ggggccgcgc cgctgccgct gctgctggtg ttagcgctca gtcaaggcat tttaaattgt
121 tgtttggcct acaatgttgg tctcccagaa gcaaaaatat tttccggtcc ttcaagtgaa
181 cagtttgggt atgcagtgca gcagtttata aatccaaaag gcaactggtt actggttggt
241 tcaccctgga gtggctttcc tgagaaccga atgggagatg tgtataaatg tcctgttgac
301 ctatccactg ccacatgtga aaaactaaat ttgcaaactt caacaagcat tccaaatgtt
361 actgagatga aaaccaacat gagcctcggc ttgatcctca ccaggaacat gggaactgga
421 ggttttctca catgtggtcc tctgtgggca cagcaatgtg ggaatcagta ttacacaacg
481 ggtgtgtgtt ctgacatcag tcctgatttt cagctctcag ccagcttctc acctgcaact
541 cagccctgcc cttccctcat agatgttgtg gttgtgtgtg atgaatcaaa tagtatttat
601 ccttgggatg cagtaaagaa ttttttggaa aaatttgtac aaggccttga tataggcccc
661 acaaagacac aggtggggtt aattcagtat gccaataatc caagagttgt gtttaacttg
721 aacacatata aaaccaaaga agaaatgatt gtagcaacat cccagacatc ccaatatggt
781 ggggacctca caaacacatt cggagcaatt caatatgcaa gaaaatatgc ctattcagca
841 gcttctggtg ggcgacgaag tgctacgaaa gtaatggtag ttgtaactga cggtgaatca
901 catgatggtt caatgttgaa agctgtgatt gatcaatgca accatgacaa tatactgagg
961 tttggcatag cagttcttgg gtacttaaac agaaacgccc ttgatactaa aaatttaata
1021 aaagaaataa aagcgatcgc tagtattcca acagaaagat actttttcaa tgtgtctgat
1081 gaagcagctc tactagaaaa ggctgggaca ttaggagaac aaattttcag cattgaaggt
1141 actgttcaag gaggagacaa ctttcagatg gaaatgtcac aagtgggatt cagtgcagat
1201 tactcttctc aaaatgatat tctgatgctg ggtgcagtgg gagcttttgg ctggagtggg
1261 accattgtcc agaagacatc tcatggccat ttgatctttc ctaaacaagc ctttgaccaa
1321 attctgcagg acagaaatca cagttcatat ttaggttact ctgtggctgc aatttctact
1381 ggagaaagca ctcactttgt tgctggtgct cctcgggcaa attataccgg ccagatagtg
1441 ctatatagtg tgaatgagaa tggcaatatc acggttattc aggctcaccg aggtgaccag
1501 attggctcct attttggtag tgtgctgtgt tcagttgatg tggataaaga caccattaca
1561 gacgtgctct tggtaggtgc accaatgtac atgagtgacc taaagaaaga ggaaggaaga
1621 gtctacctgt ttactatcaa aaagggcatt ttgggtcagc accaatttct tgaaggcccc
1681 gagggcattg aaaacactcg atttggttca gcaattgcag ctctttcaga catcaacatg
1741 gatggcttta atgatgtgat tgttggttca ccactagaaa atcagaattc tggagctgta
1801 tacatttaca atggtcatca gggcactatc cgcacaaagt attcccagaa aatcttggga
1861 tccgatggag cctttaggag ccatctccag tactttggga ggtccttgga tggctatgga
1921 gatttaaatg gggattccat caccgatgtg tctattggtg cctttggaca agtggttcaa
1981 ctctggtcac aaagtattgc tgatgtagct atagaagctt cattcacacc agaaaaaatc
2041 actttggtca acaagaatgc tcagataatt ctcaaactct gcttcagtgc aaagttcaga
2101 cctactaagc aaaacaatca agtggccatt gtatataaca tcacacttga tgcagatgga
2161 ttttcatcca gagtaacctc cagggggtta tttaaagaaa acaatgaaag gtgcctgcag
2221 aagaatatgg tagtaaatca agcacagagt tgccccgagc acatcattta tatacaggag
2281 ccctctgatg ttgtcaactc tttggatttg cgtgtggaca tcagtctgga aaaccctggc
2341 actagccctg cccttgaagc ctattctgag actgccaagg tcttcagtat tcctttccac
2401 aaagactgtg gtgaggatgg actttgcatt tctgatctag tcctagatgt ccgacaaata
2461 ccagctgctc aagaacaacc ctttattgtc agcaaccaaa acaaaaggtt aacattttca
2521 gtaacactga aaaataaaag ggaaagtgca tacaacactg gaattgttgt tgatttttca
2581 gaaaacttgt tttttgcatc attctcccta ccggttgatg ggacagaagt aacatgccag
2641 gtggctgcat ctcagaagtc tgttgcctgc gatgtaggct accctgcttt aaagagagaa
2701 caacaggtga cttttactat taactttgac ttcaatcttc aaaaccttca gaatcaggcg
2761 tctctcagtt tccaagcctt aagtgaaagc caagaagaaa acaaggctga taatttggtc
2821 aacctcaaaa ttcctctcct gtatgatgct gaaattcact taacaagatc taccaacata
2881 aatttttatg aaatctcttc ggatgggaat gttccttcaa tcgtgcacag ttttgaagat
2941 gttggtccaa aattcatctt ctccctgaag gtaacaacag gaagtgttcc agtaagcatg
3001 gcaactgtaa tcatccacat ccctcagtat accaaagaaa agaacccact gatgtaccta
3061 actggggtgc aaacagacaa ggctggtgac atcagttgta atgcagatat caatccactg
3121 aaaataggac aaacatcttc ttctgtatct ttcaaaagtg aaaatttcag gcacaccaaa
3181 gaattgaact gcagaactgc ttcctgtagt aatgttacct gctggttgaa agacgttcac
3241 atgaaaggag aatactttgt taatgtgact accagaattt ggaacgggac tttcgcatca
3301 tcaacgttcc agacagtaca gctaacggca gctgcagaaa tcaacaccta taaccctgag
3361 atatatgtga ttgaagataa cactgttacg attcccctga tgataatgaa acctgatgag
3421 aaagccgaag taccaacagg agttataata ggaagtataa ttgctggaat ccttttgctg
3481 ttagctctgg ttgcaatttt atggaagctc ggcttcttca aaagaaaata tgaaaagatg
3541 accaaaaatc cagatgagat tgatgagacc acagagctca gtagctgaac cagcagacct
3601 acctgcagtg ggaaccggca gcatcccagc cagggtttgc tgtttgcgtg catggatttc
3661 tttttaaatc ccatattttt tttatcatgt cgtaggtaaa ctaacctggt attttaagag
3721 aaaactgcag gtcagtttgg atgaagaaat tgtggggggt gggggaggtg cggggggcag
3781 gtagggaaat aatagggaaa atacctattt tatatgatgg gggaaaaaaa gtaatcttta
3841 aactggctgg cccagagttt acattctaat ttgcattgtg tcagaaacat gaaatgcttc
3901 caagcatgac aacttttaaa gaaaaatatg atactctcag attttaaggg ggaaaactgt
3961 tctctttaaa atatttgtct ttaaacagca actacagaag tggaagtgct tgatatgtaa
4021 gtacttccac ttgtgtatat tttaatgaat attgatgtta acaagagggg aaaacaaaac
4081 acaggttttt tcaatttatg ctgctcatcc aaagttgcca cagatgatac ttccaagtga
4141 taattttatt tataaactag gtaaaatttg ttgttggttc cttttatacc acggctgccc
4201 cttccacacc ccatcttgct ctaatgatca aaacatgctt gaataactga gcttagagta
4261 tacctcctat atgtccattt aagttaggag agggggcgat atagagacta aggcacaaaa
4321 ttttgtttaa aactcagaat ataacattta tgtaaaatcc catctgctag aagcccatcc
4381 tgtgccagag gaaggaaaag gaggaaattt cctttctctt ttaggaggca caacagttct
4441 cttctaggat ttgtttggct gactggcagt aacctagtga atttttgaaa gatgagtaat
4501 ttctttggca accttcctcc tcccttactg aaccactctc ccacctcctg gtggtaccat
4561 tattatagaa gccctctaca gcctgacttt ctctccagcg gtccaaagtt atcccctcct
4621 ttacccctca tccaaagttc ccactccttc aggacagctg ctgtgcatta gatattaggg
4681 gggaaagtca tctgtttaat ttacacactt gcatgaatta ctgtatataa actccttaac
4741 ttcagggagc tattttcatt tagtgctaaa caagtaagaa aaataagcta gagtgaattt
4801 ctaaatgttg gaatgttatg ggatgtaaac aatgtaaagt aaaacactct caggatttca
4861 ccagaagtta cagatgaggc actggaaacc accaccaaat tagcaggtgc accttctgtg
4921 gctgtcttgt ttctgaagta ctttttcttc cacaagagtg aatttgacct aggcaagttt
4981 gttcaaaagg tagatcctga gatgatttgg tcagattggg ataaggccca gcaatctgca
5041 ttttaacaag caccccagtc actaggatgc agatggacca cactttgaga aacaccaccc
5101 atttctactt tttgcacctt attttctctg ttcctgagcc cccacattct ctaggagaaa
5161 cttagattaa aattcacaga cactacatat ctaaagcttt gacaagtcct tgacctctat
5221 aaacttcaga gtcctcatta taaaatggga agactgagct ggagttcagc agtgatgctt
5281 tttagtttta aaagtctatg atctgatctg gacttcctat aatacaaata cacaatcctc
5341 caagaatttg acttggaaaa g
＜110〉Attached Tongji Hospital, Tongji Univ.
＜120〉pulmonary thromboembolism related gene and application thereof
<160>142
<210>88
<211>1548
<212>DNA
＜213〉human (Homo sapiens)
<400>88
1 cagggccgag ccagcccctt caccaccagc cggccgcgcc ccgggaaggg aagtttgtgg
61 cggaggaggt tcgtacggga ggagggggag gcgcccacgc atctggggct gactcgctct
121 ttcgcaaaac gtctgggagg agtccctggg gccacaaaac tgcctcct tcctgaggccag
181 aaggagagaa gacgtgcagg gaccccgcgc acaggagctg ccctcgcgac atgggtcacc
241 cgccgctgct gccgctgctg ctgctgctcc acacctgcgt cccagcctct tggggcctgc
301 ggtgcatgca gtgtaagacc aacggggatt gccgtgtgga agagtgcgcc ctgggacagg
361 acctctgcag gaccacgatc gtgcgcttgt gggaagaagg agaagagctg gagctggtgg
421 agaaaagctg tacccactca gagaagacca acaggaccct gagctatcgg actggcttga
481 agatcaccag ccttaccgag gttgtgtgtg ggttagactt gtgcaaccag ggcaactctg
541 gccgggctgt cacctattcc cgaagccgtt acctcgaatg catttcctgt ggctcatcag
601 acatgagctg tgagaggggc cggcaccaga gcctgcagtg ccgcagccct gaagaacagt
661 gcctggatgt ggtgacccac tggatccagg aaggtgaaga agggcgtcca aaggatgacc
721 gccacctccg tggctgtggc taccttcccg gctgcccggg ctccaatggt ttccacaaca
781 acgacacctt ccacttcctg aaatgctgca acaccaccaa atgcaacgag ggcccaatcc
841 tggagcttga aaatctgccg cagaatggcc gccagtgtta cagctgcaag gggaacagca
901 cccatggatg ctcctctgaa gagactttcc tcattgactg ccgaggcccc atgaatcaat
961 gtctggtagc caccggcact cacgaaccga aaaaccaaag ctatatggta agaggctgtg
1021 caaccgcctc aatgtgccaa catgcccacc tgggtgacgc cttcagcatg aaccacattg
1081 atgtctcctg ctgtactaaa agtggctgta accacccaga cctggatgtc cagtaccgca
1141 gtggggctgc tcctcagcct ggccctgccc atctcagcct caccatcacc ctgctaatga
1201 ctgccagact gtggggaggc actctcctct ggacctaaac ctgaaatccc cctctctgcc
1261 ctggctggat ccgggggacc cctttgccct tccctcggct cccagcccta cagacttgct
1321 gtgtgacctc aggccagtgt gccgacctct ctgggcctca gttttcccag ctatgaaaac
1381 agctatctca caaagttgtg tgaagcagaa gagaaaagct ggaggaaggc cgtgggccaa
1441 tgggagagct cttgttatta ttaatattgt tgccgctgtt gtgttgttgt tattaattaa
1501 tattcatatt atttatttta tacttacata aagattttgt accagtgg
＜110〉Attached Tongji Hospital, Tongji Univ.
＜120〉pulmonary thromboembolism related gene and application thereof
<160>142
<210>89
<211>643
<212>DNA
＜213〉human (Homo sapiens)
<400>89
1 ggtagcgacg gtagctctag ccgggcctga gctgtgctag cacctccccc aggagaccgt
61 tgcagtcggc cagccccctt ctccacggta accatgtgcg accgaaaggc cgtgatcaaa
121 aatgcggaca tgtcggaaga gatgcaacag gactcggtgg agtgcgctac tcaggcgctg
181 gagaaataca acatagagaa ggacattgcg gctcatatca agaaggaatt tgacaagaag
241 tacaatccca cctggcattg catcgtgggg aggaacttcg gtagttatgt gacacatgaa
301 accaaacact tcatctactt ctacctgggc caagtggcca ttcttctgtt caaatctggt
361 taaaagcatg gactgtgcca cacacccagt gatccatcca gaaacaagga ctgcagccta
421 aattccaaat accagagact gaaattttca gccttgctaa gggaacatct cgatgtttga
481 acctttgttg tgttttgtac agggcattct ctgtactagt ttgtcgtggt tataaaacaa
541 ttagcagaat agcctacatt tgtatttatt ttctattcca tacttctgcc cacgttgttt
601 tctctcaaaa tccattcctt taaaaaataa atctgatgca ccg
＜110〉Attached Tongji Hospital, Tongji Univ.
＜120〉pulmonary thromboembolism related gene and application thereof
<160>142
<210>90
<211>1485
<212>DNA
＜213〉human (Homo sapiens)
<400>90
1 ggtgggaatg gcaggctgcg tcccactgct ccagggcctg gtcctggtcc tcgccctcca
61 tcgtgtggag ccctcagtat ttctcccggc ctccaaagca aacgacgttc tggtgaggtg
121 gaagcgtgcg ggctcctatc ttctggaaga actcttcgag ggaaacttgg aaaaagaatg
181 ttatgaagaa atctgtgtct atgaagaagc aagagaagtg tttgaaaatg aagtagtcac
241 tgatgaattc tggagacgat ataagggcgg ctccccgtgc atctcccagc cctgcctcca
301 caacggctct tgccaggaca gcatctgggg ctacacctgc acctgctccc ccggctatga
361 gggcagcaac tgcgagctgg ctaaaaatga atgtcaccca gagcggactg atgggtgtca
421 acacttctgc ctcccaggac aggaatccta cacgtgcagc tgtgctcagg gctacaggct
481 tggtgaggac cacaaacagt gtgtgcccca cgaccagtgt gcctgcgggg tgctgacctc
541 tgagaagcgt gcaccggatc tacaggacct cccgtggcag gtaaagttaa caaattccga
601 aggaaaagac ttctgtggtg gtgttataat acgggaaaat tttgtactga caacagcaaa
661 atgttcactg ttacacagga atattactgt aaaaacatat tttaacagaa cgagccaaga
721 cccgctgatg atcaagataa cgcacgtcca tgtgcacatg cggtatgacg cggacgcggg
781 ggagaatgac ctgtcactgc tggagctgga gtggcccatc cagtgcccag gtgcggggct
841 ccccgtgtgc acccctgaga aagacttcgc tgagcacctc ctcatcccac gcaccagggg
901 cctcctcagc ggctgggcac gcaatggcac tgacctgggc aactcgctga ccacgcggcc
961 tgtcacactt gtggaggggg aggagtgcgg gcaggtcctg aatgtgactg tcaccaccag
1021 gacctactgt gagagaagca gcgtggcggc catgcactgg atggatggaa gtgtggtcac
1081 cagagaacac agaggctcct ggtttctcac gggggtcctg ggctcgcagc cagtaggagg
1141 gcaggctcac atggtccttg tcaccaaggt ctccaggtac tcactctggt ttaaacagat
1201 catgaactaa ctgaaactca gctagccaga atgaacaaca caaccggaag cgggattcca
1261 agctggcact gccactgtgg agggcgctga aacttcatca cacactgaga ggccgtcaca
1321 gccccagacc acccgcttgg cccacgcagc agcagagccg ccgtttgctg ggttgtttac
1381 cgagcactgt gacctttctt tccctggaac tctttatctc aatagagacc ttaaaagaaa
1441 acatgagata cgttaaataa taaaataaga taatctgtca gtcat
＜110〉Attached Tongji Hospital, Tongji Univ.
＜120〉pulmonary thromboembolism related gene and application thereof
<160>142
<210>91
<211>3427
<212>DNA
＜213〉human (Homo sapiens)
<400>91
1 gtggattaca tcctttccct gcggaggacc agggcaagtt tcctgcctgc acggcacagg
61 agagcaaact tctacagaca gaccaaggct tccatttgct gctgacacat ggaactgagg
121 tgaaattgtg ctccatgatt ttacagattt cataacgttt aagagacggg actcaggtca
181 tcaaaatgaa agccctcatc tttgcagctg ctggcctcct gcttctgttg cccacttttt
241 gtcagagtgg catggaaaat gatacaaaca acttggcaaa gccaacctta cccattaaga
301 cctttcgtgg agctccccca aattcttttg aagagttccc cttttctgcc ttggaaggct
361 ggacaggagc cacgattact gtaaaaatta agtgccctga agaaagtgct tcacatctcc
421 atgtgaaaaa tgctaccatg gggtacctga ccagctcctt aagtactaaa ctgatacctg
481 ccatctacct cctggtgttt gtagttggtg tcccggccaa tgctgtgacc ctgtggatgc
541 ttttcttcag gaccagatcc atctgtacca ctgtattcta caccaacctg gccattgcag
601 attttctttt ttgtgttaca ttgcccttta agatagctta tcatctcaat gggaacaact
661 gggtatttgg agaggtcctg tgccgggcca ccacagtcat cttctatggc aacatgtact
721 gctccattct gctccttgcc tgcatcagca tcaaccgcta cctggccatc gtccatcctt
781 tcacctaccg gggcctgccc aagcacacct atgccttggt aacatgtgga ctggtgtggg
841 caacagtttt cttatatatg ctgccatttt tcatactgaa gcaggaatat tatcttgttc
901 agccagacat caccacctgc catgatgttc acaacacttg cgagtcctca tctcccttcc
961 aactctatta cttcatctcc ttggcattct ttggattctt aattccattt gtgcttatca
1021 tctactgcta tgcagccatc atccggacac ttaatgcata cgatcataga tggttgtggt
1081 atgttaaggc gagtctcctc atccttgtga tttttaccat ttgctttgct ccaagcaata
1141 ttattcttat tattcaccat gctaactact actacaacaa cactgatggc ttatatttta
1201 tatatctcat agctttgtgc ctgggtagtc ttaatagttg cttagatcca ttcctttatt
1261 ttctcatgtc aaaaaccaga aatcactcca ctgcttacct tacaaaatag tgaaatgatc
1321 ttagagaaca aggacagcca tcacagagaa cgtctgtttt caagaacaac ataagcatag
1381 tgcaaggagc tccatttccg agctcctaag aaatatgctt caaaggtcaa acattacaaa
1441 agcattagta gtttgtttgt ttgtttttga gactgagtct cactttatca cccagactgg
1501 cgtgcagtgg cactatcttg gctcattgca acctctgcct cccaggtcag cctcccaagt
1561 agctgggatt acaccaccat gcccagctac taaaaatact tgtattttta gtagagacgg
1621 ggtttcacca tgttgaccag gctggtcttg aactcctgac ctcaagtgat cttccggcct
1681 cagcctccca aagtgctgga ttacaggcgt gagccactga gccagccagc attagtaatt
1741 tttaaaaaca ctttatcagt attttaaaaa tgttaatgca ggagaaaaga tatcacaact
1801 ctatggaaaa tgacatttcc atttgcctta ttgctacttc aagctcttta aatcaccatc
1861 ttccctattt ctgtgagtgg tattgccatc cttgacattt gacatcattt tttattcttt
1921 ggtctctttt gactctcatg ctggtggctg cctcatcaac tgattctatc tttgtagggt
1981 ccctcaccag ggtcttttat ctagtttcac ctttgccttc ttttttcctt tttttaatag
2041 agacagtgtc tcgcttcgtc acctggctga agtgcagtag cctgatcata gctcacttca
2101 gcctccaact cctgggctca agcaatcctg ctgtctcagc ctcccaagta actaagacta
2161 caggcatgca ccaccatacc caactaattt tattttttat tttttgcaga gatggagtct
2221 cactgttgcc caggctggtc ttgaactcct ggtctcgagt gatcttccta tctcagcctc
2281 ccaaagtgct gggactacag gcatgagcca ctacgtccag gccacctcta ccttctaacc
2341 attctctcca ctgccagcct accctccacc acttcacaag tcctgccaga ttaatcttcc
2401 ttagatatca gttaggatac atcactaaaa catttccact aactccactg tttctataat
2461 aaatcataaa tctttagcct ggcattcaag gctaacttgc taatcacact tcccattaaa
2521 ccttgcttat gatataggca ccaaccaaac ctcttgctct gctatatctc cactctgcct
2581 cagactgaaa agctagtcct aacgtctttg ccttaattct gttcattttt tcaagtcctt
2641 gaaggaccat tcttccctga ttctcaggct agaagtgtca cttttcttat ctgtacttcc
2701 aaagcacttt cgtatatttt tattatggca tttatatata gttcatttat atttaaattt
2761 taattccatg aacaatcaag taccaagtat aatggagaag gtgctcatcc tctgccttcc
2821 ttgagcttct gggtgatgcc aggcccaagt ctttgtggca cccagctcca tgctttgaat
2881 actatgtggc tgaatgaatt tttaaaatct caaagcagtt aaacagcagg aaagcccatt
2941 aacttcgtac tgaaaaagca acatactgtg atgatacggg atgacatcat ttcaggttgg
3001 gcatacaaaa aagtaaggaa gctaaactaa gactatactc accaggccat ttagaagttt
3061 taaataatgc ctccactatt ttttttctta gacatagctt ttaatgggga aatggaattt
3121 tgttattaat acccattata ttcctgtaag taaatgacta tttttccctt aactcagtga
3181 ttagacagga aggaagacat tagtgattag acaggaggga agatattagt gattagacag
3241 cagggaagat attagtggta aagagtgaat gatagtagtg aatataaatg gggctgagga
3301 aactttaagc ataaaagatt cctgagatga ctttacaagt ctgtacgaat ctgccttgac
3361 tgtatatttc atactgccca acaaaacaat aaaaaacaat tttaaatgca aaaaaaaaaa
3421 aaaaaaa
＜110〉Attached Tongji Hospital, Tongji Univ.
＜120〉pulmonary thromboembolism related gene and application thereof
<160>142
<210>92
<211>1904
<212>DNA
＜213〉human (Homo sapiens)
<400>92
1 gcccgcgcgg gatccgggtg gctgcaggct gctggcttct gcggctgcgg ggtcggggtc
61 gcggccaggg ccaagccgca gcgagttcac aggcggaacc cctgcaggcg gcgcccccta
121 cgcgaggtca cccctgggaa ggagcgcagc ccacccggcc cctccgcatc cgagcaggac
181 gcccgtctcc tctccctgag gatttcaggt ctccctgtcc caggaggctt gtgccaagat
241 ggcatcagct ggagacaccc aggcaggccc acgggatgca gcagatcaga acttcgacta
301 tatgttcaaa ctgctactga taggcaacag cagtgtgggc aagacttcct tcctgttccg
361 atacgcggac gactccttca ctcccgcctt cgtcagtact gtgggcatcg atttcaaggt
421 caagaccgtc taccgccatg acaagaggat caagctgcag atctgggaca cagcgggcca
481 ggagcgctac cgcaccatca ccacggccta ctaccgggga gccatgggct tcctgctcat
541 gtatgacatc gccaatcagg aatcctttgc cgctgtgcag gactgggcca cgcaaatcaa
601 gacctactcc tgggacaacg cccaggtcat cctggtgggg aacaagtgtg acctggagga
661 cgaacgtgtt gtgcctgctg aggatggccg gaggctcgcc gacgaccttg gtttcgagtt
721 ctttgaagcc agtgccaagg agaacatcaa tgtgaagcag gtcttcgagc gcctggtgga
781 tgtcatctgc gagaagatga acgagtccct ggaacccagc tccagctcag gcagcaacgg
841 gaaaggcccg gccgtggggg atgctccagc cccccagccc agcagctgca gctgctagag
901 atggccccca accccccacc cacccctctc ctgcctcggc agggactgtg atcgaggcgt
961 gagccacagt ggttatctcc aagctcaggg caatcccttc cctcctgtca actgctcccc
1021 gactcctgca tggctcattc cttcacaatg tcgccgtggc tgccaggttc ctcaggcagc
1081 cccggtggga ggctgcggac catggggact cagctctgca tggcaggcag aggcccaggg
1141 acactgacgt gcatgagctt gctgctttcc agggtgtgtt gagggtggcc atgggtgaca
1201 cgtcccactc tttctgatgg aggggcatcc gtggtgcctt ctagcttaga accattttcc
1261 aggtctcttc tgggttgggc aggactgata ttcccaagct ggtggaagat ggttcatctt
1321 cctcgcacag tgtgggttct tggagttcat ccagggaagg cggcgcctct ttctcaggtc
1381 ctgcaggctg gtctctgagc ctgcccccac gaactttctg gattccaagg tgggatggtg
1441 atccctttga cccctgcaga ccctctactt gcgaaaagca gcattgaagc agccttttcc
1501 cattgtagaa gggacaggga gtcagatccc ctcaaccccc cggcttcagg gaccccagaa
1561 gtgccttcca agcttccccc aagatccaca tcacccacga ccctgccact gtttttgctg
1621 tgttcaccac atctctgatc ctgaagtgaa ttctggaact atggaccaca ttagactggg
1681 cagagattcg cccaacccct agcactccgg ctctgggctt tcggccagaa gttaattaac
1741 ctcagagcca ggagcctggg gctggggcct ccctcccagg ccctgtttag ctgtttagct
1801 ggttgtgttt taagcaagtt cttgcccaat catgcatcct gctagaaaag gaaatgaagc
1861 aacgttccca gccaccgcaa aaaaaaaaaa aaaaaaaaaa aaaa
＜110〉Attached Tongji Hospital, Tongji Univ.
＜120〉pulmonary thromboembolism related gene and application thereof
<160>142
<210>93
<211>1285
<212>DNA
＜213〉human (Homo sapiens)
<400>93
1 aattacaaat tcccaatgca gttacaggat cctgggaagc agagtgtctg gatggaacct
61 gagctgggtc tctgactcac ttctgacttt agttttttca agggggaaca tggcaaaggt
121 gttcagtttc atccttgtta ccaccgctct gacaatgggc agggaaattt cggcgctcga
181 ggactgtgcc caggagcaga tgcggctcag agcccaggtg cgcctgcttg agacccgggt
241 caaacagcaa caggtcaaga tcaagcagct tttgcaggag aatgaagtcc agttccttga
301 taaaggagat gagaatactg tcattgatct tggaagcaag aggcagtatg cagattgttc
361 agagattttc aatgatgggt ataagctcag tggattttac aaaatcaaac ctctccagag
421 cccagcagaa ttttctgttt attgtgacat gtccgatgga ggaggatgga ctgtaattca
481 gagacgatct gatggcagtg aaaactttaa cagaggatgg aaagactatg aaaatggctt
541 tggaaatttt gtccaaaaac atggtgaata ttggctgggc aataaaaatc ttcacttctt
601 gaccactcaa gaagactaca ctttaaaaat cgaccttgca gattttgaaa aaaatagccg
661 ttatgcacaa tataagaatt tcaaagttgg agatgaaaag aatttctacg agttgaatat
721 tggggaatat tctggaacag ctggagattc ccttgcgggg aattttcatc ctgaggtgca
781 gtggtgggct agtcaccaaa gaatgaaatt cagcacgtgg gacagagatc atgacaacta
841 tgaagggaac tgcgcagaag aagatcagtc tggctggtgg tttaacaggt gtcactctgc
901 aaacctgaat ggtgtatact acagcggccc ctacacggct aaaacagaca atgggattgt
961 ctggtacacc tggcatgggt ggtggtattc tctgaaatct gtggttatga aaattaggcc
1021 aaatgatttt attccaaatg taatttaatt gctgctgttg ggctttcgtt tctgcaattc
1081 agctttgttt aaagtgattt gaaaaatact cattctgaac atatccatgc gcaatcatga
1141 taactgttgt gagtagtgct tttcattctt ctcacttgcc tttgttactt aatgtgcttt
1201 cagtacagca gatatgcaat attcaccaaa taaatgtaga ctgtgttaaa aaaaaaaaaa
1261 aaaaaaaaaa aaaaaaaaaa aaaaa
＜110〉Attached Tongji Hospital, Tongji Univ.
＜120〉pulmonary thromboembolism related gene and application thereof
<160>142
<210>94
<211>2128
<212>DNA
＜213〉human (Homo sapiens)
<400>94
1 caagacttct ctgcattttc tgccaaaatc tgtgtcagat ttaagacaca tgcttctgca
61 agcttccatg aaggttgtgc aaaaaagttt caatccagag ttgggttcca gctttctgta
121 gctgtaagca ttggtggcca caccacctcc ttacaaagca actagaacct gcggcataca
181 ttggagagat ttttttaatt ttctggacat gaagtaaatt tagagtgctt tctaatttca
241 ggtagaagac atgtccacct tctgattatt tttggagaac attttgattt ttttcatctc
301 tctctcccca cccctaagat tgtgcaaaaa aagcgtacct tgcctaattg aaataatttc
361 attggatttt gatcagaact gattatttgg ttttctgtgt gaagttttga ggtttcaaac
421 tttccttctg gagaatgcct tttgaaacaa ttttctctag ctgcctgatg tcaactgctt
481 agtaatcagt ggatattgaa atattcaaaa tgtacagaga gtgggtagtg gtgaatgttt
541 tcatgatgtt gtacgtccag ctggtgcagg gctccagtaa tgaacatgga ccagtgaagc
601 gatcatctca gtccacattg gaacgatctg aacagcagat cagggctgct tctagtttgg
661 aggaactact tcgaattact cactctgagg actggaagct gtggagatgc aggctgaggc
721 tcaaaagttt taccagtatg gactctcgct cagcatccca tcggtccact aggtttgcgg
781 caactttcta tgacattgaa acactaaaag ttatagatga agaatggcaa agaactcagt
841 gcagccctag agaaacgtgc gtggaggtgg ccagtgagct ggggaagagt accaacacat
901 tcttcaagcc cccttgtgtg aacgtgttcc gatgtggtgg ctgttgcaat gaagagagcc
961 ttatctgtat gaacaccagc acctcgtaca tttccaaaca gctctttgag atatcagtgc
1021 ctttgacatc agtacctgaa ttagtgcctg ttaaagttgc caatcataca ggttgtaagt
1081 gcttgccaac agccccccgc catccatact caattatcag aagatccatc cagatccctg
1141 aagaagatcg ctgttcccat tccaagaaac tctgtcctat tgacatgcta tgggatagca
1201 acaaatgtaa atgtgttttg caggaggaaa atccacttgc tggaacagaa gaccactctc
1261 atctccagga accagctctc tgtgggccac acatgatgtt tgacgaagat cgttgcgagt
1321 gtgtctgtaa aacaccatgt cccaaagatc taatccagca ccccaaaaac tgcagttgct
1381 ttgagtgcaa agaaagtctg gagacctgct gccagaagca caagctattt cacccagaca
1441 cctgcagctg tgaggacaga tgcccctttc ataccagacc atgtgcaagt ggcaaaacag
1501 catgtgcaaa gcattgccgc tttccaaagg agaaaagggc tgcccagggg ccccacagcc
1561 gaaagaatcc ttgattcagc gttccaagtt ccccatccct gtcattttta acagcatgct
1621 gctttgccaa gttgctgtca ctgttttttt cccaggtgtt aaaaaaaaaa tccattttac
1681 acagcaccac agtgaatcca gaccaacctt ccattcacac cagctaagga gtccctggtt
1741 cattgatgga tgtcttctag ctgcagatgc ctctgcgcac caaggaatgg agaggagggg
1801 acccatgtaa tccttttgtt tagttttgtt tttgtttttt ggtgaatgag aaaggtgtgc
1861 tggtcatgga atggcaggtg tcatatgact gattactcag agcagatgag gaaaactgta
1921 gtctctgagt cctttgctaa tcgcaactct tgtgaattat tctgattctt ttttatgcag
1981 aatttgattc gtatgatcag tactgacttt ctgattactg tccagcttat agtcttccag
2041 tttaatgaac taccatctga tgtttcatat ttaagtgtat ttaaagaaaa taaacaccat
2101 tattcaagcc aaaaaaaaaa aaaaaaaa
＜110〉Attached Tongji Hospital, Tongji Univ.
＜120〉pulmonary thromboembolism related gene and application thereof
<160>142
<210>95
<211>5207
<212>DNA
＜213〉human (Homo sapiens)
<400>95
1 agagttatat tgtgccattt atggaaaaac tctccccact gctcttggct ttgacagtag
61 gaatcaggtt atatatggtc tctcggtttg aagatatttg tcattaaaaa ccagaacaag
121 ggctctgaga tagggtcctt tcctgaccta ctctggtaaa gtctttatcc tcaggatgca
181 aggataccac cctcttcctg tggaaagtgt cgaatcacat gcagagctct aagtctttca
241 gttactttgg agtgcagaac catttcagac atgctgaggg ggactctact gtgcgcggtg
301 ctcgggcttc tgcgcgccca gcccttcccc tgtccgccag cttgcaagtg tgtcttccgg
361 gacgccgcgc agtgctcggg gggcgacgtg gcgcgcatct ccgcgctggg cctgcccacc
421 aacctcacgc acatcctgct cttcggaatg ggccgcggcg tcctgcagag ccagagcttc
481 agcggcatga ccgtcctgca gcgcctcatg atctccgaca gccacatttc cgccgttgcc
541 cccggcacct tcagtgacct gataaaactg aaaaccctga ggctgtcgcg caacaaaatc
601 acgcatcttc caggtgcgct gctggataag atggtgctcc tggagcagtt gtttttggac
661 cacaatgcgc taaggggcat tgaccaaaac atgtttcaga aactggttaa cctgcaggag
721 ctcgctctga accagaatca gctcgatttc cttcctgcca gtctcttcac gaatctggag
781 aacctgaagt tgttggattt atcgggaaac aacctgaccc acctgcccaa ggggttgctt
841 ggagcacagg ctaagctcga gagacttctg ctccactcga accgccttgt gtctctggat
901 tcggggctgt tgaacagcct gggcgccctg acggagctgc agttccaccg aaatcacatc
961 cgttccatcg cacccggggc cttcgaccgg ctcccaaacc tcagttcttt gacgctttcg
1021 agaaaccacc ttgcgtttct cccctctgcg ctctttcttc attcgcacaa tctgactctg
1081 ttgactctgt tcgagaaccc gctggcagag ctcccggggg tgctcttcgg ggagatgggg
1141 ggcctgcagg agctgtggct gaaccgcacc cagctgcgca ccctgcccgc cgccgccttc
1201 cgcaacctga gccgcctgcg gtacttaggg gtgactctga gcccgcggct gagcgcgctt
1261 ccgcagggcg ccttccaggg ccttggcgag ctccaggtgc tcgccctgca ctccaacggc
1321 ctgaccgccc tccccgacgg cttgctgcgc ggcctcggca agctgcgcca ggtgtccctg
1381 cgccgcaaca ggctgcgcgc cctgccccgt gccctcttcc gcaatctcag cagcctggag
1441 agcgtccagc tcgaccacaa ccagctggag accctgcctg gcgacgtgtt tggggctctg
1501 ccccggctga cggaggtcct gttggggcac aactcctggc gctgcgactg tggcctgggg
1561 cccttcctgg ggtggctgcg gcagcaccta ggcctcgtgg gcggggaaga gcccccacgg
1621 tgcgcaggcc ctggggcgca cgccggcctg ccgctctggg ccctgccggg gggtgacgcg
1681 gagtgcccgg gcccccgggg cccgcctccc cgccccgctg cggacagctc ctcggaagcc
1741 cctgtccacc cagccttggc tcccaacagc tcagaaccct gggtgtgggc ccagccggtg
1801 accacgggca aaggtcaaga tcatagtccg ttctgggggt tttattttct gcttttagct
1861 gttcaggcca tgatcaccgt gatcatcgtg tttgctatga ttaaaattgg ccaactcttt
1921 cgaaaattaa tcagagagag agcccttggg taaaccaatg ggaaaatctt ctaattactt
1981 agaacctgac cagatgtggc tcggagggga atccagaccc gctgctgtct tgctctccct
2041 cccctcccca ctcctcctct cttcttcctc ttctctctca ctgccacgcc ttcctttccc
2101 tcctcctccc cctctccgct ctgtgctctt cattctcacg ggcccgcaac ccctcctctc
2161 tctgtccccg cccgtctctg gaaactgagc ttgacgtttg taaactgtgg ttgcctgcct
2221 tcccagctcc acgcggtgtg cgctgacact gccggggggc tggactgtgt tggacccatc
2281 cttgccccgc tgtgcctggc ttggcctctg gtggagagag ggacctcttc agtgtctact
2341 gagtaagggg acagctccag gccggggctg tctcctgcac agagtaagcc ggtaaatgtt
2401 tgtgaaatca atgcgtggat aaaggaacac atgccatcca agtgatgatg gcttttcctg
2461 gagggaaagg ataggctgtt gctctatcta attttttgtt tttgtttttg gacagtctag
2521 ctctgtggcc caggctggcg tgcagtgggc cgtctcagtt cactgcagcc tccgccctcc
2581 aggttcaagt gattctcatg cctcagcgtt ctgagtagct gggattagag gcgtgtgcca
2641 ctacacccgg ctaatttttg tactttttaa agtagagacg ggctttgcca tattggcctg
2701 gctgatctca aactcctggt cttgaactcc tggccacaag tgatctgccc gccttagcct
2761 cccaaagtgc tgggattaca ggcgcaagcc actacacctg ccctcttcat cgaattttat
2821 ttgagaagta gagctcttgc cattttttcc cttgctccat ttttctcact ttatgtctct
2881 ctgacctatg ggctacttgg gagagcactg gactccattc atgcatgagc attttcagga
2941 taagcgactt ctgtgaggct gagagaggaa gaaaacacgg agccttccct ccaggtgccc
3001 agtgtaggtc cagcgtgttt cctgagcctc ctgtgagttt ccacttgctt tacatccatg
3061 caacatgtca ttttgaaact ggattgattt gcatttcctg gaactctgcc acctcatttc
3121 acaagcattt atggagcagt taacatgtga ctggtattca tgaatataat gataagcttg
3181 attctagttc agctgctgtc acagtctcat ttgttcttcc aactgaaagc cgtaaaacct
3241 ttgttgcttt aattgaatgt ctgtgcttat gagaggcagt ggttaaaaca ttttctggcg
3301 agttgacaac tgtgggttca aatcccagct ctaccactta ctaactgcat gggactttgg
3361 gtaagacacc tgcttacatt ctctaagcct tggtttcctg aaccttaaaa caggataaca
3421 tagtacctgc ttcatagagt tttgtgagaa ttaaaggcaa taaagcatat aatgacttag
3481 cccagcggcc tgcagacaat acatgttaat gaatgttagc tattattact aaagatgagc
3541 aattattatt ggcatcatga tttctaaaga agagctttga gttggtattt ttctctgtgt
3601 ataagggtaa gtccgaactt tctcatactg gaggttacat tcacatcagt ctgtcttccc
3661 ctgcggatgg cctcagccct gggtggccag gctctgtgct cacagtccag agcaatggat
3721 cctccaacac caccaggtgg atgtggagca ggagagctgg atcgtggcat ttgtttctgg
3781 gttctgcagt tgggagttgg tttctgggtt ctccattggt ctacttgtct agtcccatac
3841 cagactcacg gtctccatta ttggagcttt aataattttt ggtatagggt catctctcca
3901 ccttgttttt cttctattct tggttctttg caattctatg aatatttcag ggtcagcatg
3961 tcaactccat tgaaaaaccc tgctgggatt ttaatagaac ttacagctca cgcctgtaat
4021 cccagcactt tgggaggctg aggtgggtgg atcacaggtc aggagtttga gaacagctgg
4081 ccaagatggt gaaaccccgt ctctactaaa aatacaaaaa ttagctgggt gcggtggcag
4141 gtgcctgtag tcccagctac ttgggacacc gaggcaggag aatcacttga acccgggagg
4201 cggaggttgc agtgagccga gatcgtgcca ctgcactcta gcctgggcga cagagcgaga
4261 ctccatctca aaaaaaaaga aaaagaaaat tgcagtaaat ttaaaactaa tttggggaag
4321 aatctgtatt tttacaatac ctagtgttct tgccagtaag catggttcat cttcccattt
4381 atttacgtca ttttaaatct ttcagtgatg ttttagaatt ttttttataa aaaccttcac
4441 tataagaaca gaaaaccaaa caccgcatgt tctcactcat aggtgggaat tgaacaatga
4501 gaacacttgg acacagggcg gggaacgtca cacgcctgga ctgttggggg ggtggctggg
4561 agagggatag tgttaggaga aatacctaat gtaaatgacg agttaatggt gcagccaacc
4621 aacctggcac atgtattcat atgtaacaaa cctgcacgtt gtgcacatgt accctagaac
4681 ttaaagtata ttaaaaaaag aaaccttggc actgattttg ttagatttat tcctaggtat
4741 ccttcctctt ttttgatttg tcattgctat tgtagatggc atctttttaa aaagttatat
4801 tttctaaagc aaaaaataaa aaaagttgta tttctaattt ttattaccaa tatataagaa
4861 tgtaatttat ttttacataa ttatcttatg tctagtaata attctgataa tttgcttctt
4921 cctattaaaa ccttacaccc attattgatt tatttttctg ttttaaaata tcttcctgca
4981 ctggctaaaa cctccactat aatgttgagc agaacagtga ggcatcctta gaactatctt
5041 ggttgcaaag ggtaggtctc taatgtttca tcaataaatg tgatgtttct agtctgagtt
5101 tgctaagtat attttaaaat aatcagtaaa gttagatttt atccattttt atcttaacta
5161 ttgagatgct catatcattt ttcttcttca atgtgttaaa atggtga
＜110〉Attached Tongji Hospital, Tongji Univ.
＜120〉pulmonary thromboembolism related gene and application thereof
<160>142
<210>96
<211>2964
<212>DNA
＜213〉human (Homo sapiens)
<400>96
1 cagagccacg ggcgcccgcc ccgccccgcg ccgccccgcg ccggctccgc agctcgcgcc
61 cgcccgcctg ccggcccgcc cggcgccggg ccatggcgct gctgcgggat gtgtcgctgc
121 aggacccgcg ggaccgcttc gagctgctgc agcgcgtggg ggccgggacc tatggcgacg
181 tctacaaggc ccgcgacacg gtcacgtccg aactggccgc cgtgaagata gtcaagctag
241 acccagggga cgacatcagc tccctccagc aggaaatcac catcctgcgt gagtgccgcc
301 accccaatgt ggtggcctac attggcagct acctcaggaa tgaccgcttg tggatctgca
361 tggagttctg cggagggggc tccctgcagg agatttacca tgccactggg cccctggagg
421 agcggcagat tgcctacgtc tgccgagagg cactgaaggg gctccaccac ctgcattctc
481 aggggaagat ccacagagac atcaagggag ccaaccttct cctcactctc cagggagatg
541 tcaaactggc tgactttggg gtgtcaggcg agctgacagc gtctgtggcc aagaggaggt
601 ctttcattgg gactccctac tggatggctc ccgaggtggc tgctgtggag cgcaaaggtg
661 gctacaatga gctatgtgac gtctgggccc tgggcatcac tgccattgag ctgggcgagc
721 tgcagccccc tctgttccac ctgcacccca tgagggccct gatgctcatg tcgaagagca
781 gcttccagcc gcccaaactg agagataaga ctcgctggac ccagaatttc caccactttc
841 tcaaactggc cctgaccaag aatcctaaga agaggccgac agcagagaag ctcctgcagc
901 acccgttcac gactcagcag ctccctcggg ccctcctcac acagctgctg gacaaagcca
961 gtgaccctca tctggggacc ccctcccctg aggactgtga gctggagacc tatgacatgt
1021 ttccagacac cattcactcc cgggggcagc acggcccagc cgagaggacc ccctcggaga
1081 tccagtttca ccaggtgaaa tttggcgccc cacgcaggaa ggaaactgac ccactgaatg
1141 agccgtggga ggaagagtgg acactactgg gaaaggaaga gttgagtggg agcctgctgc
1201 agtcggtcca ggaggccctg gaggaaagga gtctgactat tcggtcagcc tcagaattcc
1261 aggagctgga ctccccagac gataccatgg gaaccatcaa gcgggccccg ttcctagggc
1321 cactccccac tgaccctcca gcagaggagc ctctgtccag tcccccagga accctgcccc
1381 cacctccttc aggccccaac agctccccac tgctgcccac ggcctgggcc accatgaagc
1441 agcgggagga tcctgagagg tcatcctgcc acgggctccc cccaactccc aaggtgcata
1501 tgggcgcctg cttctccaag gtcttcaatg gctgccccct gcggatccac gctgctgtca
1561 cctggattca ccctgttact cgggaccagt tcctggtggt aggggccgag gaaggcatct
1621 acacactcaa cctgcatgaa ctgcatgagg atacgctgga gaagctgatt tcacatcgct
1681 gctcctggct ctactgcgtg aacaacgtgc tgctgtcact ctcagggaaa tccacgcaca
1741 tctgggccca tgacctccca ggcctgtttg agcagcggag gctacagcaa caggttcccc
1801 tctccatccc caccaaccgc ctcacccagc gcatcatccc caggcgcttt gctctgtcca
1861 ccaagattcc tgacaccaaa ggctgcttgc agtgtcgtgt ggtgcggaac ccctacacgg
1921 gtgccacctt cctgctggcc gccctgccca ccagcctgct cctgctgcag tggtatgagc
1981 cgctgcagaa gtttctgctg ctgaagaact tctccagccc tctgcccagc ccagctggga
2041 tgctggagcc gctggtgctg gatgggaagg agctgccgca ggtgtgtgtt ggggccgagg
2101 ggcctgaggg gcccggctgc cgcgtcctgt tccatgtcct gcccctggag gctggcctga
2161 cgcccgacat cctcatccca cctgagggga tcccaggctc ggcccagcag gtgatccagg
2221 tggacaggga cacaatccta gtcagctttg aacgctgtgt gaggattgtc aacatgcagg
2281 gcgagcccac ggccacactg gcacctgagc tgacctttga tttccccatc gagactgtgg
2341 tgtgcctgca ggacagtgtg ctggccttct ggagccatgg gatgcaaggc cgaagcctgg
2401 ataccaatga ggtgacccag gagatcacag atgaaacaag gatcttccga gtgcttgggg
2461 cccacagaga catcatcctg gagagcattc ccactgacaa cccagaggcg cacagcaacc
2521 tctacatcct cacgggccac cagagcacct actaagagca gcgggcctgt ccaggggctc
2581 cccgccccac cccacgcctt agctgcaggc ccttttgggc aaaggggccc atcctagacc
2641 agaggagccc aggccctggc cctgctgggg ctgaaggtca gaagtaatcc tgagaaatgt
2701 ttcaggcctg gggagggagg ggagcccccg acgcctctgc aataactgga ccagggggag
2761 ctgctgtcac tcccccatcc ccgaggcagc ccagtcccta gtgcccaagg cagggaccct
2821 gggcctgggc catccattcc attttgttcc acatttcctt tctactcttt ctgccaagag
2881 cctgcccctg catttgtcct gggaaacacg gtatttaaga gagaactata ttggtattaa
2941 agctggtttg ttttaaaaaa aaaa
＜110〉Attached Tongji Hospital, Tongji Univ.
＜120〉pulmonary thromboembolism related gene and application thereof
<160>142
<210>97
<211>2512
<212>DNA
＜213〉human (Homo sapiens)
<400>97
1 ggctggtgca aggagccaca gtgggctgcc tggggggctg atgccaccat tccaggagcc
61 tcggtgaaga gaggatatcc atctgtgtag ccgcttctct atacgggatt cgagctccat
121 ggcagcccgt ctgctcctcc tgggcatcct tctcctgctg ctgcccctgc ccgtccctgc
181 cccgtgccac acagccgcac gctcagagtg caagcgcagc cacaagttcg tgcctggtgc
241 atggctggcc ggggagggtg tggacgtgac cagcctccgc cgctcgggct ccttcccagt
301 ggacacacaa aggttcctgc ggcccgacgg cacctgcacc ctctgtgaaa atgccctaca
361 ggagggcacc ctccagcgcc tgcctctggc gctcaccaac tggcgggccc agggctctgg
421 ctgccagcgc catgtaacca gggccaaagt cagctccact gaagctgtgg cccgggatgc
481 ggctcgtagc atccgcaacg actggaaggt cgggctggac gtgactccta agcccaccag
541 caatgtgcat gtgtctgtgg ccggctcaca ctcacaggca gccaactttg cagcccagaa
601 gacccaccag gaccagtaca gcttcagcac tgacacggtg gagtgccgct tctacagttt
661 ccatgtggta cacactcccc cgctgcaccc tgacttcaag agggccctcg gggacctgcc
721 ccaccacttc aacgcctcca cccagcccgc ctacctcagg cttatctcca actacggcac
781 ccacttcatc cgggctgtgg agctgggtgg ccgcatatcg gccctcactg ccctgcgcac
841 ctgcgagctg gccctggaag ggctcacgga caacgaggtg gaggactgcc tgactgtcga
901 ggcccaggtc aacataggca tccacggcag catctctgcc gaagccaagg cctgtgagga
961 gaagaagaag aagcacaaga tgacggcctc cttccaccaa acctaccggg agcgccactc
1021 ggaagtggtt ggcggccatc acacctccat taacgacctg ctgttcggga tccaggccgg
1081 gcccgagcag tactcagcct gggtaaactc gctgcccggc agccctggcc tggtggacta
1141 caccctggaa cccctgcacg tgctgctgga cagccaggac ccgcggcggg aggcactgag
1201 gagggccctg agtcagtacc tgacggacag ggctcgctgg agggactgca gccggccgtg
1261 cccaccaggg cggcagaaga gcccccgaga cccatgccag tgtgtgtgcc atggctcagc
1321 ggtcaccacc caggactgct gccctcggca gaggggcctg gcccagctgg aggtgacctt
1381 catccaagca tggggcctgt ggggggactg gttcactgcc acggatgcct atgtgaagct
1441 cttctttggt ggccaggagc tgaggacgag caccgtgtgg gacaataaca accccatctg
1501 gtcagtgcgg ctggattttg gggatgtgct cctggccaca ggggggcccc tgaggttgca
1561 ggtctgggat caggactctg gcagggacga tgacctcctt ggcacctgtg atcaggctcc
1621 caagtctggt tcccatgagg tgagatgcaa cctgaatcat ggccacctaa aattccgcta
1681 tcatgccagg tgcttgcccc acctgggagg aggcacctgc ctggactatg tcccccaaat
1741 gcttctgggg gagcctccag gaaaccggag tggggccgtg tggtgagaac agtgagcttg
1801 gaaaggacca gtatgcttgg actgaagggg ttctcacagt gggagccagg gctgtcttcg
1861 tattcccatt agaccaagct tgtccaaccc gaggcccgca tgcggcccag gatggctttg
1921 aatgcggccc aacgcaaatt cgcaaacttt cttaaaacat tatgagtttc tttttgctat
1981 tttttttttt tttttagctc atcggctatc gttagtgcta gtggatttta catgtggccc
2041 aacacaattc ttcttccaac gtggcccaga gaagccaaaa gattggatac gcatcagaca
2101 gatggaaaag ggagattcag actgtttttc agggaggtgg ctgggtttac acgctaatcc
2161 cgattcaccc tgtccaaact gcctaagccc tccgccattc tcaagccctg cagtcacagc
2221 tacacagatc acagcttcag ccaggagctg ggcagaaggc caagaggctg ttcccaccag
2281 gctgctcagg gctggtcttt taggaccctt cccttgagcc ctctatggtg tggcaaagcc
2341 ttcattgcct taactggagc cccatcagct ccagctgctc tgtcttcttt gcccacaatg
2401 ctttgcccct gagacaaatg gaggcctgtc ctgacctgtc tcaccatgta catagcttga
2461 taaagggcca ataaatatga tgttatggtg aaaaaaaaaa aaaaaaaaaa aa
＜110〉Attached Tongji Hospital, Tongji Univ.
＜120〉pulmonary thromboembolism related gene and application thereof
<160>142
<210>98
<211>1949
<212>DNA
＜213〉human (Homo sapiens)
<400>98
1 ttgaagatct ctcagttaag tctacatgaa aaggatggtt tcttggagct tccacaaact
61 taaaaccatg aaacatctat tattgctact attgtgtgtt tttctagtta agtcccaagg
121 tgtcaacgac aatgaggagg gtttcttcag tgcccgtggt catcgacccc ttgacaagaa
181 gagagaagag gctcccagcc tgaggcctgc cccaccgccc atcagtggag gtggctatcg
241 ggctcgtcca gccaaagcag ctgccactca aaagaaagta gaaagaaaag cccctgatgc
301 tggaggctgt cttcacgctg acccagacct gggggtgttg tgtcctacag gatgtcagtt
361 gcaagaggct ttgctacaac aggaaaggcc aatcagaaat agtgttgatg agttaaataa
421 caatgtggaa gctgtttccc agacctcctc ttcttccttt cagtacatgt atttgctgaa
481 agacctgtgg caaaagaggc agaagcaagt aaaagataat gaaaatgtag tcaatgagta
541 ctcctcagaa ctggaaaagc accaattata tatagatgag actgtgaata gcaatatccc
601 aactaacctt cgtgtgcttc gttcaatcct ggaaaacctg agaagcaaaa tacaaaagtt
661 agaatctgat gtctcagctc aaatggaata ttgtcgcacc ccatgcactg tcagttgcaa
721 tattcctgtg gtgtctggca aagaatgtga ggaaattatc aggaaaggag gtgaaacatc
781 tgaaatgtat ctcattcaac ctgacagttc tgtcaaaccg tatagagtat actgtgacat
841 gaatacagaa aatggaggat ggacagtgat tcagaaccgt caagacggta gtgttgactt
901 tggcaggaaa tgggatccat ataaacaggg atttggaaat gttgcaacca acacagatgg
961 gaagaattac tgtggcctac caggtgaata ttggcttgga aatgataaaa ttagccagct
1021 taccaggatg ggacccacag aacttttgat agaaatggag gactggaaag gagacaaagt
1081 aaaggctcac tatggaggat tcactgtaca gaatgaagcc aacaaatacc agatctcagt
1141 gaacaaatac agaggaacag ccggtaatgc cctcatggat ggagcatctc agctgatggg
1201 agaaaacagg accatgacca ttcacaacgg catgttcttc agcacgtatg acagagacaa
1261 tgacggctgg ttaacatcag atcccagaaa acagtgttct aaagaagacg gtggtggatg
1321 gtggtataat agatgtcatg cagccaatcc aaacggcaga tactactggg gtggacagta
1381 cacctgggac atggcaaagc atggcacaga tgatggtgta gtatggatga attggaaggg
1441 gtcatggtac tcaatgagga agatgagtat gaagatcagg cccttcttcc cacagcaata
1501 gtccccaata cgtagatttt tgctcttctg tatgtgacaa catttttgta cattatgtta
1561 ttggaatttt ctttcataca ttatattcct ctaaaactct caagcagacg tgagtgtgac
1621 tttttgaaaa aagtatagga taaattacat taaaatagca catgattttc ttttgttttc
1681 ttcatttctc ttgctcacca agaagtaaca aaagtatagt tttgacagag ttggtgttca
1741 taatttcagt tctagttgat tgcgagaatt ttcaaataag gaagaggggt cttttatcct
1801 tgtcgtagga aaaccatgac ggaaaggaaa aactgatgtt taaaagtcca cttttaaaac
1861 tatatttatt tatgtaggat ctgtcaaaga aaacttccaa aaagatttat taattaaacc
1921 agactctgtt gcaataaaaa aaaaaaaaa
＜110〉Attached Tongji Hospital, Tongji Univ.
＜120〉pulmonary thromboembolism related gene and application thereof
<160>142
<210>99
<211>2764
<212>DNA
＜213〉human (Homo sapiens)
<400>99
1 ctctaaagct tagagccaag atggcgggat ccaggcaaag gggtctccgg gccagagttc
61 ggccgctgtt ctgcgccttg ctgctgtcac tcggtcgctt cgtccggggc gacggcgtgg
121 gaggagaccc cgcggtcgcg ttgccacatc gccgtttcga gtacaaatac agcttcaagg
181 ggccgcacct ggtgcagagc gacgggaccg tgcccttctg ggcccacgcg gggaatgcta
241 ttccaagttc agatcaaatt cgagtagcac catctttaaa aagccaaaga ggctcagtgt
301 ggacaaagac aaaagcggcc tttgagaact gggaagttga ggtgacattt cgagtgactg
361 gaagaggtcg aattggagct gatggcctag caatttggta tgcagaaaat caaggcttgg
421 agggccctgt gtttggatca gctgatctgt ggaatggtgt tggaatattt tttgattctt
481 ttgacaatga tggaaagaaa aataatcctg ctatagtaat tataggcaac aatggacaaa
541 tccattatga ccatcaaaat gacggggcta gtcaagcttt ggcaagttgc cagagggact
601 tccgcaacaa accctatcct gtccgagcaa agattaccta ttaccagaac acactgacag
661 taatgatcaa taatggcttt acaccagata aaaatgatta tgaattttgt gccaaagtgg
721 aaaatatgat tatccctgca caagggcatt ttggaatatc tgctgcaact ggaggtcttg
781 cagatgacca tgatgtcctt tcttttctga ctttccagtt gactgaacct ggaaaagagc
841 cgcccacacc agataaagaa atttcggaaa aggaaaaaga aaagtatcag gaggaatttg
901 agcactttca acaagaattg gataaaaaaa aagaggaatt ccagaagggc caccccgacc
961 tccaagggca gcctgcggag gaaatatttg agagtgtagg agatcgagag ctaagacaag
1021 tctttgaagg acagaatcgt attcatcttg aaatcaagca gctgaaccgg cagttagata
1081 tgattcttga tgaacagaga agatatgtct cttccttaac agaggaaatc tctaaaagag
1141 gagcaggaat gcctgggcag catgggcaga ttactcaaca agaactggat actgttgtga
1201 aaactcagca tgagattctg agacaagtaa atgaaatgaa aaattccatg agtgaaaccg
1261 tcagactggt cagtggaatg cagcaccctg gctctgctgg aggcgtctat gagacaacac
1321 agcacttcat tgacatcaaa gagcacctgc acatagtaaa gagggacata gataacttag
1381 tgcagcgaaa tatgccatca aatgaaaagc cgaaatgccc agaactacca ccatttccat
1441 catgtttgtc tacggtccac ttcattatat ttgttgtggt gcaaactgta ttattcattg
1501 gttatatcat gtataggtct cagcaagaag cagctgccaa aaaattcttt tgactaccat
1561 tttcctgtgt acttcatcta tttgtgtaca aaatgatgtc gttttgaggg aatttaagta
1621 tttaaattgc ttcatagtct aaattattaa ttttcttaat aaaataactg tttaaacatt
1681 gatttgcagt taagaataaa ccttaaagca aagacaacca cattttaatt tgttcacagt
1741 atgtaaatct gtctaaattt cagtgaattt ctggtcagta tgatgcagcc tctgagcaga
1801 tattgaccag taagagggta aataaagtgg gggcaacccc tggatatgaa tgttaccccc
1861 taagtctcca atattgcagg tttccctgta taacgtaaac acacttgccc tcatgcctcc
1921 cagaatatga ggtctaatta agaagtccca tcaggtttat tttgtaacca aagtcttttt
1981 tagaggtcag acttcctaat caaaggcctg ggcctgcagt cctttcatct taatgcaact
2041 tcctttgaaa tcaaagaata ttttgtctga gagctttaag gatctggtaa tagacttcaa
2101 aatgttaagt gaaatttttt ttcctctatt tatcaatgat atatttcact tttaaaggaa
2161 attttggagg aaaatatagc tgctttttgc ctaaaaaacc ttgtgggtgg aaatattcct
2221 ctgagaatgg cttttatagg tattttgcct ggtaatgtat tcattcatga ttgcccatat
2281 tcttgaatgt ttcttcattc caatggggtc aggtcaatat tatgaaaata atttttatat
2341 ttatatttgt aactaagaat ttatttctcc ctttactaca cgatgtaaat tcacgtcaaa
2401 ttcgatgatc tgaggattta aattcacaaa acctgccact acattctggt ttacattagt
2461 tacttcatgc tggctggggt tagtgaccat ttgcatactc ttttaaatca aggaggctgt
2521 agtagaggca gttttaagat tcttgaaggc aaaatttgaa aaacagtgaa tacttctaat
2581 tgtttccttt tagtgccaga actaagacat tgtgaagcac ttgttagtaa acttaacctt
2641 gaaatgtcag actggaagga gtttttatgt ctttgtgcat acttctgggt attacagaaa
2701 cagtctgtaa ataacatttt aagatgcaaa tttaattctg ttcacagctg atttatactg
2761 attt
＜110〉Attached Tongji Hospital, Tongji Univ.
＜120〉pulmonary thromboembolism related gene and application thereof
<160>142
<210>100
<211>3158
<212>DNA
＜213〉human (Homo sapiens)
<400>100
1 aaaccggaac ggggcccaac ttctggggcc tggagaaggg aaacgaagtc ccccccggtt
61 tcccgaggtt gcctttcctc gggcatcctt ggtttcggcg ggacttcgca gggcggatat
121 aaagaacggc gcctttggga agaggcggag accggcttta aagaaagaag tcttggtcct
181 gcggcttggg cgaggcaagg gcgaggcaag ggcgctttct gccgacgctc cccgtggccc
241 tacgatcccc cgcgcgtccg ccgctgttct aaggagagaa gtgggggccc cccaggctcg
301 cgcgtggagc gaagcagcat gggcagtcgg tgcgcgctgg ccctggcggt gctctcggcc
361 ttgctgtgtc aggtctggag ctctggggtg ttcgaactga agctgcagga gttcgtcaac
421 aagaaggggc tgctggggaa ccgcaactgc tgccgcgggg gcgcggggcc accgccgtgc
481 gcctgccgga ccttcttccg cgtgtgcctc aagcactacc aggccagcgt gtcccccgag
541 ccgccctgca cctacggcag cgccgtcacc cccgtgctgg gcgtcgactc cttcagtctg
601 cccgacggcg ggggcgccga ctccgcgttc agcaacccca tccgcttccc cttcggcttc
661 acctggccgg gcaccttctc tctgattatt gaagctctcc acacagattc tcctgatgac
721 ctcgcaacag aaaacccaga aagactcatc agccgcctgg ccacccagag gcacctgacg
781 gtgggcgagg agtggtccca ggacctgcac agcagcggcc gcacggacct caagtactcc
841 taccgcttcg tgtgtgacga acactactac ggagagggct gctccgtttt ctgccgtccc
901 cgggacgatg ccttcggcca cttcacctgt ggggagcgtg gggagaaagt gtgcaaccct
961 ggctggaaag ggccctactg cacagagccg atctgcctgc ctggatgtga tgagcagcat
1021 ggattttgtg acaaaccagg ggaatgcaag tgcagagtgg gctggcaggg ccggtactgt
1081 gacgagtgta tccgctatcc aggctgtctc catggcacct gccagcagcc ctggcagtgc
1141 aactgccagg aaggctgggg gggccttttc tgcaaccagg acctgaacta ctgcacacac
1201 cataagccct gcaagaatgg agccacctgc accaacacgg gccaggggag ctacacttgc
1261 tcttgccggc ctgggtacac aggtgccacc tgcgagctgg ggattgacga gtgtgacccc
1321 agcccttgta agaacggagg gagctgcacg gatctcgaga acagctactc ctgtacctgc
1381 ccacccggct tctacggcaa aatctgtgaa ttgagtgcca tgacctgtgc ggacggccct
1441 tgctttaacg ggggtcggtg ctcagacagc cccgatggag ggtacagctg ccgctgcccc
1501 gtgggctact ccggcttcaa ctgtgagaag aaaattgact actgcagctc ttcaccctgt
1561 tctaatggtg ccaagtgtgt ggacctcggt gatgcctacc tgtgccgctg ccaggccggc
1621 ttctcgggga ggcactgtga cgacaacgtg gacgactgcg cctcctcccc gtgcgccaac
1681 gggggcacct gccgggatgg cgtgaacgac ttctcctgca cctgcccgcc tggctacacg
1741 ggcaggaact gcagtgcccc cgtcagcagg tgcgagcacg caccctgcca caatggggcc
1801 acctgccacc agaggggcca cggctatgtg tgcgaatgtg cccgaagcta cgggggtccc
1861 aactgccagt tcctgctccc cgagctgccc ccgggcccag cggtggtgga cctcactgag
1921 aagctagagg gccagggcgg gccattcccc tgggtggccg tgtgcgccgg ggtcatcctt
1981 gtcctcatgc tgctgctggg ctgtgccgct gtggtggtct gcgtccggct gaggctgcag
2041 aagcaccggc ccccagccga cccctgccgg ggggagacgg agaccatgaa caacctggcc
2101 aactgccagc gtgagaagga catctcagtc agcatcatcg gggccacgca gatcaagaac
2161 accaacaaga aggcggactt ccacggggac cacagcgccg acaagaatgg cttcaaggcc
2221 cgctacccag cggtggacta taacctcgtg caggacctca agggtgacga caccgccgtc
2281 agggacgcgc acagcaagcg tgacaccaag tgccagcccc agggctcctc aggggaggag
2341 aaggggaccc cgaccacact caggggtgga gaagcatctg aaagaaaaag gccggactcg
2401 ggctgttcaa cttcaaaaga caccaagtac cagtcggtgt acgtcatatc cgaggagaag
2461 gatgagtgcg tcatagcaac tgaggtgtaa aatggaagtg agatggcaag actcccgttt
2521 ctcttaaaat aagtaaaatt ccaaggatat atgccccaac gaatgctgct gaagaggagg
2581 gaggcctcgt ggactgctgc tgagaaaccg agttcagacc gagcaggttc tcctcctgag
2641 gtcctcgacg cctgccgaca gcctgtcgcg gcccggccgc ctgcggcact gccttccgtg
2701 acgtcgccgt tgcactatgg acagttgctc ttaagagaat atatatttaa atgggtgaac
2761 tgaattacgc ctaagaagca tgcactgcct gagtgtatat tttggattct tatgagccag
2821 tcttttcttg aattagaaac acaaacactg cctttattgt cctttttgat acgaagatgt
2881 gctttttcta gatggaaaag atgtgtgtta ttttttggat ttgtaaaaat atttttcatg
2941 atatctgtaa agcttgagta ttttgtgatg ttcgtttttt ataatttaaa ttttggtaaa
3001 tatgtacaaa ggcacttcgg gtctatgtga ctatattttt ttgtatataa atgtatttat
3061 ggaatattgt gccaatgtta tttgagtttt ttactgtttt gttaatgaag aaattccttt
3121 ttaaaatatt tttccaaaat aaattttatg aggaattc
＜110〉Attached Tongji Hospital, Tongji Univ.
＜120〉pulmonary thromboembolism related gene and application thereof
<160>142
<210>102
<211>1678
<212>DNA
＜213〉human (Homo sapiens)
<400>102
1 gcatatactg tcatcatctt ggaaagaaaa ggctgagaac gtaaaactga ggacagagga
61 ggaaagcagg gtgacccctg atgttgccct agaaaatgga aaacaaaaca cagcaaaaca
121 gaaaaacaga agatctgact ctgcctttag ccaggaaaac agtttggggg agtaaaaagt
181 attagggaaa agagtgggca ttttgcctgg aaaaaaggtt tctagagcca tctgggcttt
241 ccgggaacct ggaccagact ctggcccagt aggatgtccc cgtgtcctcc ccagcagagc
301 aggaacaggg tgatacagct gtccacttca gagctaggag agatggaact gacttggcag
361 gagatcatgt ccatcaccga gctgcagggt ctgaatgctc caagtgagcc atcatttgag
421 ccccaagccc cagctccata ccttggacct ccaccaccca caacttactg cccctgctca
481 atccacccag attctggctt cccacttcct ccaccacctt atgagctccc agcatccaca
541 tcccatgtcc cagatccccc atactcctat ggcaacatgg ccataccagt ctccaagcca
601 ctgagcctct caggcctgct cagtgagccg ctccaagacc ccttagccct cctggacatt
661 gggctgccag cagggccacc taagccccaa gaagacccag aatccgactc aggattatcc
721 ctcaactata gcgatgctga atctcttgag ctggagggga cagaggctgg tcggcggcgc
781 agcgaatatg tagagatgta cccagtggag tacccctact cactcatgcc caactccttg
841 gcccactcca actatacctt gccagctgct gagaccccct tggccttaga gccctcctca
901 ggccctgtgc gggctaagcc cactgcacgg ggggaggcag ggagtcggga tgaacgtcgg
961 gccttggcca tgaagattcc ttttcctacg gacaagattg tcaacttgcc ggtagatgac
1021 tttaatgagc tattggcaag gtacccgctg acagagagcc agctagcgct agtccgggac
1081 atccgacgac ggggcaaaaa caaggtggca gcccagaact gccgcaagag gaagctggaa
1141 accattgtgc agctggagcg ggagctggag cggctgacca atgaacggga gcggcttctc
1201 agggcccgcg gggaggcaga ccggaccctg gaggtcatgc gccaacagct gacagagctg
1261 taccgtgaca ttttccagca ccttcgggat gaatcaggca acagctactc tcctgaagag
1321 tacgcgctgc aacaggctgc cgatgggacc atcttccttg tgccccgggg gaccaagatg
1381 gaggccacag actgagctgg cccagagggg tggaactgct gatgggattt ccttcattcc
1441 cttctgataa aggtactccc caaccctgag tcccagaagg agctgagttc tctagaccag
1501 aagaggatga caatggcaac aagtgtttgg aagttccaag gtgtgttcaa agaggcttgc
1561 cttgagggag ggctggaatc tgtcttccct gactcggctc ctcaggtctt tagcctccac
1621 cttgtctaag ctttggtcta taaagtgcgc tacagaaaaa aaaaaaaaaa aaaaaaaa
＜110〉Attached Tongji Hospital, Tongji Univ.
＜120〉pulmonary thromboembolism related gene and application thereof
<160>142
<210>101
<211>3026
<212>DNA
＜213〉human (Homo sapiens)
<400>101
1 tcgacccacg cgtccggatt gaggggttga ctgagcgttg cgagccttag ctttctcccg
61 aacgccagcg ctgaggacac gatgtcgcgg ctctcccgct cactgctttg ggccgccacc
121 tgcctgggcg tgctctgcgt gctgtccgcg gacaagaaca cgacccagca cccgaacgtg
181 acgactttag cgcccatctc caacgtaacc tcggcgccgg tgacgtccct cccgctggtc
241 accactccgg caccagaaac ctgtgaaggt cgaaacagct gcgtttcctg ttttaatgtt
301 agcgttgtta atactacctg cttttggata gaatgtaaag atgagagcta ttgttcacat
361 aactcaacag ttagtgattg tcaagtgggg aacacgacag acttctgttc cgtttccacg
421 gccactccag tgccaacagc caattctaca gctaaaccca cagttcagcc ctccccttct
481 acaacttcca agacagttac tacatcaggt acaacaaata acactgtgac tccaacctca
541 caacctgtgc gaaagtctac ctttgatgca gccagtttca ttggaggaat tgtcctggtc
601 ttgggtgtgc aggctgtaat tttctttctt tataaattct gcaaatctaa agaacgaaat
661 taccacactc tgtaaacaga cccattgaat taataaggac tggtgattca tttgtgtaac
721 tcactgaagc caaaatacta tcttttaaga tgtcccacat ggaagacgct attccaggat
781 ctttaaattt ccatggatgc atataggatg tttgggagca tcatccgtga agaaaaaatc
841 aattaaatca ttgtgttcaa caggaatatt taaaatattc tgcatgaatc ctgtggctgt
901 cttattttaa atagctgctg ctgtgggatt atattttttt tccttaacat gccaaatata
961 actttctgaa agtgatggaa aatgttgtct tgtgcagaca acatcatggc tcttggcagt
1021 ttaaatttag taattttaat ttagtgaaca gaattgagaa gaacgtgcca aatgagaatc
1081 aattaggtgg atttttggct gtcatttcaa aagtggaata aatttattaa tttagtagta
1141 ctaaatggta tccttagatt aaaattttgt gcttgataac agctgttttt tctacattag
1201 aaataagatg ccacacaagg aactacattc cagatttaaa gaaatgaaag gataccatta
1261 gtgtgtataa cagattattg ttcatacttg taaagcatct tatgtcattg agaatataaa
1321 gaacagtgcc ttagaagaca gtgaaaggta agctctagct taatgtctat gatttgttct
1381 ttgacattaa ggaaggtaag gattggtcag aggatgtaac ttgatgtgag cagtagtaaa
1441 cctgttttag atatcatact gttaatattt tattgaaaat ttatttcaga gcggagaaac
1501 ttaagctaaa gtctgttata cagaattgaa agccttcgta tcttgaacct cccaacattt
1561 ttcttatggc tgttgaaaag tatagagcta aattgattta attacacttt cctttgtact
1621 ttaaaaaaaa gtatgctagc actattgtac cttgaaagga tttccaccag actgtcttga
1681 gtagtgactt ctttggtgag gcaagaagga tatacattat tttagaatca tttactattt
1741 aaatgagaca atcatattat tttagaatca tttattttaa atgagacaat cattttaagt
1801 tttaagataa cagaagtgac caatgtaatt tcacaacacc taaggatttt ttggttgatc
1861 aggttactgt agatttttac tgattgtcct ggatgaatag actgtgcttt ttctttttct
1921 ctcccttcct tcttggtttc ccatagtata ataagcatgc atactttaac ttctatagtt
1981 ttctccttta gagggtcgtc ttcagtttta gaggtttact tctcccttgc ctttgactca
2041 ttggactagt gcagaggctt taagtagttt aaaatgggct tttgcttttc taggtcatta
2101 acgtttttta tttagtttct ttagccaata gtggctgagt ttcgcacttg attttcaata
2161 ttttatagta agaaatgaca aactgctttg tttcatttca taaacaaact ctgcatttag
2221 ataactatta aaggttgtta agatgaagat ttactgtttc tttgttactc gttggtacag
2281 ctgtttgttt tacttgcaca tttgtacata tacttaatgt tttcaagtgc cttaattgtt
2341 taaaatctct ggcttcaaag tttcttgggg aaaggtcggt ttacctcaca ttttttgttt
2401 ccattagtaa tattctaggt acctcacaaa atgtattatg gtgccatggc tgttagtttt
2461 tagtgagtgc tgtaggatta attcgaaaat aggcagaatt ccattcctcc caaggtggca
2521 aaaattagct atactgatgt aattgtcatt tacctgggta tgaattccct gacacacatt
2581 catgtcaaca tatgtagcaa attttgtgaa aacataacaa tttgaagctt ctgtaatttt
2641 gagcactgct ctaacaacaa gcataatata aaattagtta gattttgcaa gtctacaaat
2701 gagctcttgc aacagaactc acagcctttt tacttttttc ccctaacttt agcaatgtag
2761 tatcttgagc cattaatttt tgggtttttt taaaatccag aaggtatata gaaacctttt
2821 cagatttttc atctgatttg ttcttgcaga tgttcttcta tcaaatacct tattttacct
2881 tacagatatt tgttgcacag gcagatactg ctgtatttag acatttctat ttcagttcat
2941 taaaaactgc aaaaccaatc tgtatcatgt accaaactga cttaaaataa atctacatgt
3001 ttattgaaaa aaaaaaaaaa aaaaaa
＜110〉Attached Tongji Hospital, Tongji Univ.
＜120〉pulmonary thromboembolism related gene and application thereof
<160>142
<210>103
<211>1502
<212>DNA
＜213〉human (Homo sapiens)
<400>103
1 cctgcgtccc cgccccgcgc agccgccgcg ctcctgcgct ccgaggtccg aggttcccga
61 gatgaaggtc tggctgctgc ttggtcttct gctggtgcac gaagcgctgg aggatgttac
121 tggccaacac cttcccaaga acaagcgtcc aaaagaacca ggagagaata gaatcaaacc
181 taccaacaag aaggtgaagc ccaaaattcc taaaatgaag gacagggact cagccaattc
241 agcaccaaag acgcagtcta tcatgatgca agtgctggat aaaggtcgct tccagaaacc
301 cgccgctacc ctgagtctgc tggcggggca aactgtagag cttcgatgta aagggagtag
361 aattgggtgg agctaccctg cgtatctgga cacctttaag gattctcgcc tcagcgtcaa
421 gcagaatgag cgctacggcc agttgactct ggtcaactcc acctcggcag acacaggtga
481 attcagctgc tgggtgcagc tctgcagcgg ctacatctgc aggaaggacg aggccaaaac
541 gggctccacc tacatctttt ttacagagaa aggagaactc tttgtacctt ctcccagcta
601 cttcgatgtt gtctacttga acccggacag acaggctgtg gttccttgtc gggtgaccgt
661 gctgtcggcc aaagtcacgc tccacaggga attcccagcc aaggagatcc cagccaatgg
721 aacggacatt gtttatgaca tgaagcgggg ctttgtgtat ctgcaacctc attccgagca
781 ccagggtgtg gtttactgca gggcggaggc cgggggcaga tctcagatct ccgtcaagta
841 ccagctgctc tacgtggcgg ttcccagtgg ccctccctca acaaccatct tggcttcttc
901 aaacaaagtg aaaagtgggg acgacatcag tgtgctctgc actgtcctgg gggagcccga
961 tgtggaggtg gagttcacct ggatcttccc agggcagaag gatgaaaggc ctgtgacgat
1021 ccaagacact tggaggttga tccacagagg actgggacac accacgagaa tctcccagag
1081 tgtcattaca gtggaagact tcgagacgat tgatgcagga tattacattt gcactgctca
1141 gaatcttcaa ggacagacca cagtagctac cactgttgag ttttcctgac ttggaaaagg
1201 aaatgtaatg aacttatgga aagcccattt gtgtacacag tcagctttgg ggttcctttt
1261 attagtgctt tgccagaggc tgatgtcaag caccacaccc caaccccagc gtctcgtgag
1321 tccgacccag acatccaaac taaaaggaag tcatccagtc tattcacaga agtgttaact
1381 tttctaacag aaagcatgat tttgattgct tacctacata cgtgttccta gtttttatac
1441 atgtgtaaac aattttatat aatcaatcat ttctattaaa tgagcacgtt tttgtaaaaa
1501 at
＜110〉Attached Tongji Hospital, Tongji Univ.
＜120〉pulmonary thromboembolism related gene and application thereof
<160>142
<210>105
<211>1496
<212>DNA
＜213〉human (Homo sapiens)
<400>105
1 cgcactccct gctgggtgag cagcactgta aagatgaagc tggctaactg gtactggctg
61 agctcagctg ttcttgccac ttacggtttt ttggttgtgg caaacaatga aacagaggaa
121 attaaagatg aaagagcaaa ggatgtctgc ccagtgagac tagaaagcag agggaaatgc
181 gaagaggcag gggagtgccc ctactaggta agcctgcccc ccttgactat tcagctcccg
241 aagcaattca gcaggatcga ggaggtgttc aaagaagtcc aaaacctcaa ggaaatcgta
301 aatagtctaa agaaatcttg ccaagactgc aagctgcagg ctgatgacaa cggagaccca
361 ggcagaaacg gactgttgtt acccagtaca ggagccccgg gagaggttgg tgataacaga
421 gttagagaat tagagagtga ggttaacaag ctgtcctctg agctaaagaa tgccaaagag
481 gagatcaatg tacttcatgg tcgcctggag aagctgaatc ttgtaaatat gaacaacata
541 gaaaattatg ttgacagcaa agtggcaaat ctaacatttg ttgtcaatag tttggatggc
601 aaatgttcaa agtgtcccag ccaagaacaa atacagtcac gtccagttca acatctaata
661 tataaagatt gctctgacta ctacgcaata ggcaaaagaa gcagtgagac ctacagagtt
721 acacctgatc ccaaaaatag tagctttgaa gtttactgtg acatggagac catgggggga
781 ggctggacag tgctgcaggc acgtctcgat gggagcacca acttcaccag aacatggcaa
841 gactacaaag caggctttgg aaacctcaga agggaatttt ggctggggaa cgataaaatt
901 catcttctga ccaagagtaa ggaaatgatt ctgagaatag atcttgaaga ctttaatggt
961 gtcgaactat atgccttgta tgatcagttt tatgtggcta atgagtttct caaatatcgt
1021 ttacacgttg gtaactataa tggcacagct ggagatgcat tacgtttcaa caaacattac
1081 aaccacgatc tgaagttttt caccactcca gataaagaca atgatcgata tccttctggg
1141 aactgtgggc tgtactacag ttcaggctgg tggtttgatg catgtctttc tgcaaactta
1201 aatggcaaat attatcacca aaaatacaga ggtgtccgta atgggatttt ctggggtacc
1261 tggcctggtg taagtgaggc acaccctggt ggctacaagt cctccttcaa agaggctaag
1321 atgatgatca gacccaagca ctttaagcca taaatcactc tgttcattcc tccaggtatt
1381 cgttatctaa tagggcaatt aattccttca gcactttaga atatgccttg tttcatattt
1441 ttcatagcta aaaaatgttt gacatccttt gagatatttt attactaaaa tctgcc
＜110〉Attached Tongji Hospital, Tongji Univ.
＜120〉pulmonary thromboembolism related gene and application thereof
<160>142
<210>106
<211>1641
<212>DNA
＜213〉human (Homo sapiens)
<400>106
1 gaattcgggg gctgcggaga gggtgcttaa ctgaggggca tgatggggga ggcggccgtg
61 ccgcggggct tgtcgttgcg cgaggacagc ttcacgcgct tctcgtcgca gaacaatgtg
121 tacgggctgg caggcggcgc cggcgggcgc ggggagctgc tggccgccac ccttaaaggc
181 aaggtgctcg gcttccgtta ccaagacctc cgacagaaaa tccggccagt ggccaaggag
241 ctgcagttca actacattcc cgtggatgcg gagattgtct ccatcgacac tttcaacaag
301 tcacccccca agcggggtct ggttgtgggg atcacgttca tcaaggattc aggggacaag
361 ggcagcccct tcctgaacat ttactgcgac tacgagaccg gctctgtgta caaccttgtc
421 tctattgccc agagctgcct gaacctggag ctccagttca ctccgttcca gctgtgccat
481 gcggaggtcc aggtcgggga tcaacttgag actgtgtttc tcttgagtgg gaacgacccg
541 gccattcatc tctacaagga gaacgagggc ctgcatcagt ttgaggaaca gcccgtggaa
601 aacctcttcc cagagctgac gaacctgacc agtagcgtcc tctggctgga cgtccacaac
661 ttccccggca cgtcccggcg cctctcagct ctgggctgtc agagtggtta tgtccgtgtc
721 gcccacgtgg accagcggag tcgagaggtt ctgcagatgt ggtcggtcct gcaggacggt
781 cccatctccc gagtgattgt gttcagcctc tcggccgcca aggagaccaa ggacaggcca
841 ctacaagatg agtacagcgt gctcgtggcc agcatgttgg agccagcagt ggtgtatcgg
901 gacctgctga accggggtct tgaagaccag cttctcctgc ccggcagtga ccagtttgac
961 agcgtcctct gcagcctggt caccgatgtg gatttggatg ggcggccaga agtcctggtg
1021 gccacctatg gacaggaact gctgtgttat aagtaccggg gcccagagtc ggggcttcct
1081 gaggcccagc acgggttcca tctgctgtgg cagcggagct tctccagtcc cctgctggcc
1141 atggctcacg tggacctgac cggggatggg ctgcaggagc ttgccgtggt ctccctgaag
1201 ggcgtgcaca tcctgcagca cagcctgatt caggcctcag agctggtctt gacccggctt
1261 cgaacatcaa gtggagcaga ggagacgtcg gcctacaggg gttggaggac ggggcaggtg
1321 cagggcctgc tgagaatgca gcctcttaag cacccatgca cccactcttc ccagacctgg
1381 ggcgactcat ggcgtgctca cctccagccg ctggtggggg gtgtcctgaa ggacaggatg
1441 ctctccccag acctccccag ggtggtgaag ctgtgccctg gggccccagc taacccactc
1501 ctctctctgt acgtcaatgt ccctatttga aagcagggat gatcccattc caccctgtcc
1561 actctggatg agaattggcc acctgatggt tatttatacg tccagaagaa catccccaaa
1621 aaaaaaaaaa aaaccgaatt c
＜110〉Attached Tongji Hospital, Tongji Univ.
＜120〉pulmonary thromboembolism related gene and application thereof
<160>142
<210>106
<211>1641
<212>DNA
＜213〉human (Homo sapiens)
<400>106
1 gaattcgggg gctgcggaga gggtgcttaa ctgaggggca tgatggggga ggcggccgtg
61 ccgcggggct tgtcgttgcg cgaggacagc ttcacgcgct tctcgtcgca gaacaatgtg
121 tacgggctgg caggcggcgc cggcgggcgc ggggagctgc tggccgccac ccttaaaggc
181 aaggtgctcg gcttccgtta ccaagacctc cgacagaaaa tccggccagt ggccaaggag
241 ctgcagttca actacattcc cgtggatgcg gagattgtct ccatcgacac tttcaacaag
301 tcacccccca agcggggtct ggttgtgggg atcacgttca tcaaggattc aggggacaag
361 ggcagcccct tcctgaacat ttactgcgac tacgagaccg gctctgtgta caaccttgtc
421 tctattgccc agagctgcct gaacctggag ctccagttca ctccgttcca gctgtgccat
481 gcggaggtcc aggtcgggga tcaacttgag actgtgtttc tcttgagtgg gaacgacccg
541 gccattcatc tctacaagga gaacgagggc ctgcatcagt ttgaggaaca gcccgtggaa
601 aacctcttcc cagagctgac gaacctgacc agtagcgtcc tctggctgga cgtccacaac
661 ttccccggca cgtcccggcg cctctcagct ctgggctgtc agagtggtta tgtccgtgtc
721 gcccacgtgg accagcggag tcgagaggtt ctgcagatgt ggtcggtcct gcaggacggt
781 cccatctccc gagtgattgt gttcagcctc tcggccgcca aggagaccaa ggacaggcca
841 ctacaagatg agtacagcgt gctcgtggcc agcatgttgg agccagcagt ggtgtatcgg
901 gacctgctga accggggtct tgaagaccag cttctcctgc ccggcagtga ccagtttgac
961 agcgtcctct gcagcctggt caccgatgtg gatttggatg ggcggccaga agtcctggtg
1021 gccacctatg gacaggaact gctgtgttat aagtaccggg gcccagagtc ggggcttcct
1081 gaggcccagc acgggttcca tctgctgtgg cagcggagct tctccagtcc cctgctggcc
1141 atggctcacg tggacctgac cggggatggg ctgcaggagc ttgccgtggt ctccctgaag
1201 ggcgtgcaca tcctgcagca cagcctgatt caggcctcag agctggtctt gacccggctt
1261 cgaacatcaa gtggagcaga ggagacgtcg gcctacaggg gttggaggac ggggcaggtg
1321 cagggcctgc tgagaatgca gcctcttaag cacccatgca cccactcttc ccagacctgg
1381 ggcgactcat ggcgtgctca cctccagccg ctggtggggg gtgtcctgaa ggacaggatg
1441 ctctccccag acctccccag ggtggtgaag ctgtgccctg gggccccagc taacccactc
1501 ctctctctgt acgtcaatgt ccctatttga aagcagggat gatcccattc caccctgtcc
1561 actctggatg agaattggcc acctgatggt tatttatacg tccagaagaa catccccaaa
1621 aaaaaaaaaa aaaccgaatt c
＜110〉Attached Tongji Hospital, Tongji Univ.
＜120〉pulmonary thromboembolism related gene and application thereof
<160>142
<210>107
<211>2732
<212>DNA
＜213〉human (Homo sapiens)
<400>107
1 gtctttattt cagtcccgga tccgcgggcg caggcccagc tcaggccccc agggatggac
61 gtcgtggacc ctgacatttt caatagagac ccccgggacc actatgacct gctacagcgg
121 ctgggtggcg gcacgtatgg ggaagtcttt aaggctcgag acaaggtgtc aggggacctg
181 gtggcactga agatggtgaa gatggagcct gatgatgatg tctccaccct tcagaaggaa
241 atcctcatat tgaaaacttg ccggcacgcc aacatcgtgg cctaccatgg gagttatctc
301 tggttgcaga aactctggat ctgcatggaa ttctgtgggg ctggttctct ccaggacatc
361 taccaagtga caggctccct gtcagagctc cagattagct atgtctgccg ggaagtgctc
421 cagggactgg cctatttgca ctcacagaag aagatacaca gggacatcaa gggagctaac
481 atcctcatca atgatgctgg ggaggtcaga ttggctgact ttggcatctc ggcccagatt
541 ggggctacac tggccagacg cctctctttc attgggacac cctactggat ggctccggaa
601 gtggcagctg tggccctgaa gggaggatac aatgagctgt gtgacatctg gtccctgggc
661 atcacggcca tcgaactggc cgagctacag cgagcgctct ttgatgtgca ccctctcaga
721 gttctcttcc tcatgaccaa gagtggctac cagcctcccc gactgaagga aaaaggcaaa
781 tggtcggctg ccttccacaa cttcatcaaa gtcactctga ctaagagtcc caagaaacga
841 cccagcgcca ccaagatgct cagtcatcaa ctggtatccc agcctgggct gaatcgaggc
901 ctgatcctgg atcttcttga caaactgaag aatcccggga aaggaccctc cattggggac
961 attgaggatg aggagcccga gctaccccct gctatccctc ggcggatcag atccacccac
1021 cgctccagct ctctggggat cccagatgca gactgctgtc ggcggcacat ggagttcagg
1081 aagctccgag gaatggagac cagaccccca gccaacaccg ctcgcctaca gcctcctcga
1141 gacctcagga gcagcagccc caggaagcaa ctgtcagagt cgtctgacga tgactatgac
1201 gacgtggaca tccccacccc tgcagaggac acacctcctc cacttccccc caagcccaag
1261 ttccgttctc catcagacga gggtcctggg agcatggggg atgatgggca gctgagcccg
1321 ggggtgctgg tccggtgtgc cagtgggccc ccaccaaaca gcccccgtcc tgggcctccc
1381 ccatccacca gcagccccca cctcaccgcc cattcagaac cctcactctg gaacccaccc
1441 tcccgggagc ttgacaagcc cccacttctg ccccccaaga aggaaaagat gaagagaaag
1501 ggatgtgccc ttctcgtaaa gttgttcaat ggctgccccc tccggatcca cagcacggcc
1561 gcctggacac atccctccac caaggaccag cacctgctcc tgggggcaga ggaaggcatc
1621 ttcatcctga accggaatga ccaggaggcc acgctggaaa tgctctttcc tagccggact
1681 acgtgggtgt actccatcaa caacgttctc atgtctctct caggaaagac cccccacctg
1741 tattctcata gcatccttgg cctgctggaa cggaaagaga ccagagcagg aaaccccatc
1801 gctcacatta gcccccaccg cctactggca aggaagaaca tggtttccac caagatccag
1861 gacaccaaag gctgccgggc gtgctgtgtg gcggagggtg cgagctctgg gggcccgttc
1921 ctgtgcggtg cattggagac gtccgttgtc ctgcttcagt ggtaccagcc catgaacaaa
1981 ttcctgcttg tccggcaggt gctgttccca ctgccgacgc ctctgtccgt gttcgcgctg
2041 ctgaccgggc caggctctga gctgcccgct gtgtgcatcg gcgtgagccc cgggcggccg
2101 gggaagtcgg tgctcttcca cacggtgcgc tttggcgcgc tctcttgctg gctgggcgag
2161 atgagcaccg agcagagggg acccgtgcag gtgacccagg tagaggaaga tatggtgatg
2221 gtgttgatgg atggctctgt gaagctggtg accccggagg ggtccccagt ccggggactt
2281 cgcacacctg agatccccat gaccgaagcg gtggaggccg tggctatggt tggaggtcag
2341 cttcaggcct tctggaagca tggagtgcag gtgtgggctc taggctcgga tcagctgcta
2401 caggagctga gagaccctac cctcactttc cgtctgcttg gctcccccag gctggagtgc
2461 agtggcacga tctcgcctca ctgcaacctc ctcctcccag gttcaagcaa ttctcctgcc
2521 tcagcctccc gagtagctgg gattacaggc ctgtagtggt ggagacacgc ccagtggatg
2581 atcctactgc tcccagcaac ctctacatcc aggaatgagt ccctaggggg gtgtcaggaa
2641 ctagtccttg caccccctcc cccatagaca cactagtggt catggcatgt cctcatctcc
2701 caataaacat gactttagcc tctgcaaaaa aa
＜110〉Attached Tongji Hospital, Tongji Univ.
＜120〉pulmonary thromboembolism related gene and application thereof
<160>142
<210>108
<211>4973
<212>DNA
＜213〉human (Homo sapiens)
<400>108
1 cagctatcaa aaaggccata aggattttgt ccccaaattt cacatgagct accttgcttc
61 aaactactga gatgaagggg gcaagattat ttgtccttct ttctagttta tggagtgggg
121 gcattgggct taacaacagt aagcattctt ggactatacc tgaggatggg aactctcaga
181 agactatgcc ttctgcttca gttcctccaa ataaaataca aagtttgcaa atactgccaa
241 ccactcgggt catgtcggcg gagatagcta caactccaga ggcaagaact tctgaagaca
301 gtcttcttaa atcaacactg cctccctcag aaacaagtgc acctgctgag ggtgtgagaa
361 atcaaactct cacatccaca gagaaagcag aaggagtggt caagttacag aatcttaccc
421 tcccaaccaa cgctagcatc aagttcaatc ctggagcaga atcagtggtc ctttccaatt
481 ctacactgaa atttcttcag agctttgcca gaaagtcaaa tgaacaagca acttctctaa
541 acacagttgg aggcactgga ggcattggag gcgttggagg cactggaggc gtgggaaatc
601 gagccccacg ggaaacatac ctcagccggg gtgacagcag ttccagccaa agaactgact
661 accaaaaatc aaatttcgaa acaactagag gaaagaattg gtgtgcttat gtacatacca
721 ggttatctcc cacagtgata ttggacaacc aggtcactta tgtcccaggt gggaaaggac
781 cttgtggctg gaccggtgga tcctgtcctc agagatctca gaagatatcc aatcctgtct
841 ataggatgca acataaaatt gtcacctcat tggattggag gtgctgtcct ggatacagtg
901 ggccgaaatg tcaactaaga gcccaggaac agcaaagttt gatacacacc aaccaggctg
961 aaagtcatac agctgttggc agaggagtag ctgagcagca gcagcagcaa ggctgtggtg
1021 acccagaagt gatgcaaaaa atgactgatc aggtgaacta ccaggcaatg aaactgactc
1081 ttctgcagaa gaagattgac aatatttctt tgactgtgaa tgatgtaagg aacacttact
1141 cctccctaga aggaaaagtc agcgaagata aaagcagaga atttcaatct cttctaaaag
1201 gtctaaaatc caaaagcatt aatgtactga taagagacat agtaagagaa caatttaaaa
1261 tttttcaaaa tgacatgcaa gagactgtag cacagctctt caagactgta tcaagtctat
1321 cagaggacct cgaaagcacc aggcaaataa ttcaaaaagt taatgaatct gtggtttcaa
1381 tagcagccca gcaaaagttt gttttggtgc aagagaatcg gcccactttg actgatatag
1441 tggaactaag gaatcacatt gtgaatgtaa ggcaagaaat gactcttaca tgtgagaagc
1501 ctattaaaga actagaagta aagcagactc atttagaagg tgctctagaa caggaacact
1561 caagaagcat tctgtattat gaatccctca ataaaactct ttctaaattg aaggaagtac
1621 atgagcagct tttatcaact gaacaggtat cagaccagaa gaatgctcca gctgctgagt
1681 cagttagcaa taatgtcact gagtacatgt ctactttaca tgaaaatata aagaagcaga
1741 gtttgatgat gctgcaaatg tttgaagatt tgcacattca agaaagcaag attaacaatc
1801 tcaccgtctc tttggagatg gagaaagagt ctctcagagg tgaatgtgaa gacatgttat
1861 ccaaatgcag aaatgatttt aaatttcaac ttaaggacac agaagagaat ttacatgtgt
1921 taaatcaaac attggctgaa gttctctttc caatggacaa taagatggac aaaatgagtg
1981 agcaactaaa tgatttgact tatgatatgg agatccttca acccttgctt gagcagggag
2041 catcactcag acagacaatg acatatgaac aaccaaagga agcaatagtg ataaggaaaa
2101 agatagaaaa tctgactagt gctgtcaata gtctaaattt tattatcaaa gaacttacaa
2161 aaagacacaa cttacttaga aatgaagtac agggtcgtga tgatgcctta gaaagacgta
2221 tcaatgaata tgccttagaa atggaagatg gcctcaataa gacaatgact attataaata
2281 atgctattga tttcattcaa gataactatg ccctaaaaga gactttaagt actattaagg
2341 ataatagtga gatccatcat aaatgtacct ccgatatgga aactattttg acatttattc
2401 ctcagttcca ccgtctgaat gattctattc agactttggt caatgacaat cagagatata
2461 actttgtttt gcaagtcgcc aagacccttg caggtattcc cagagatgag aaactaaatc
2521 agtccaactt ccaaaagatg tatcaaatgt tcaatgaaac cacttcccaa gtgagaaaat
2581 accagcaaaa tatgagtcat ttggaagaaa aactactctt aactaccaag atttccaaaa
2641 attttgagac tcggttgcaa gacattgagt ctaaagttac ccagacgctc ataccttatt
2701 atatttcagt taaaaaaggc agtgtagtta caaatgagag agatcaggct cttcaactgc
2761 aagtattaaa ttccagattt aaggcgttgg aagcaaaatc tatccatctt tcaattaact
2821 tcttttcgct taacaaaact ctccacgaag ttttaacaat gtgtcacaat gcttctacaa
2881 gtgtgtcaga actgaatgct accatcccta agtggataaa acattccctg ccagatattc
2941 aacttcttca gaaaggtcta acagaatttg tggaaccaat aattcaaata aaaactcaag
3001 ctgccctatc taatttaact tgttgtatag atcgatcgtt gcctggtagt ctggcaaatg
3061 ttgtcaagtc tcagaagcaa gtaaaatcat tgccaaagaa aattaacgca cttaagaaac
3121 caacggtaaa tcttaccaca gtcctgatag gccggactca aagaaacacg gacaacataa
3181 tatatcctga ggagtattca agctgtagtc ggcatccgtg ccaaaatggg ggcacgtgca
3241 taaatggaag aactagcttt acctgtgcct gcagacatcc ttttactggt gacaactgca
3301 ctatcaagct tgtggaagaa aatgctttag ctccagattt ttccaaagga tcttacagat
3361 atgcacccat ggtggcattt tttgcatctc atacgtatgg aatgactata cctggtccta
3421 tcctgtttaa taacttggat gtcaattatg gagcttcata taccccaaga actggaaaat
3481 ttagaattcc gtatcttgga gtatatgttt tcaagtacac catcgagtca tttagtgctc
3541 atatttctgg atttttagtg gttgatggaa tagacaagct tgcatttgag tctgaaaata
3601 ttaacagtga aatacactgt gatagggttt taactgggga tgccttatta gaattaaatt
3661 atgggcagga agtctggtta cgacttgcaa aaggaacaat tccagccaag tttccccctg
3721 ttactacatt tagtggctat ttattatatc gtacataagt tagtatgaaa aacagactat
3781 cacctttatt gagaaacagc cagtgttttc atttatcttt gcttgcacat ctgctctgtt
3841 ttggtttttc tacaggaaat gaaaatcaac ttgttttttt aatatgagta aacttgtatg
3901 tctattttat aaaattattt gaatattgtt taatgtctga atatgaaaga gttcttgatc
3961 ctaaagaaat ttagtggcac agaaaacaaa gtgaatttgt tagcataatt attcctattc
4021 ttatttcttc attttaagtc attgcaatgg aaagtaatat tataaaatgg taattacaac
4081 atattatcag tcacagtttt ctttccaatt aaacacttaa cttttgttat tccctgtata
4141 taaatatata acacacattt tctagattca caaatttaaa taaattactc aaaaaatgaa
4201 aattgatttt gtaaactttt atttttactc tttacgttga gttgatcaat tttccatact
4261 aagattttca ttcagaatca aaattaagaa agttggactg aaaatatgaa aaatgcttaa
4321 ctattgttct cttcctataa ttctctaatt ataacatagt aatttacatg tagttggaca
4381 tgtacactca agtctaagaa tatatgagtg gatcatttac cgccccccgc cccacaacat
4441 ctataagggg caaaaagtct ttttctaata agtattcttc tatggtagta cctacagatc
4501 tgcccttctt cttctaaagg gtaagtcata atctgtgtaa tactacaatt tatgggatgc
4561 tcactatgcc ctgtttctct tctaaacaat ttacatgtaa tgtctcattc ctcacaataa
4621 cccttgtaaa gtgggcatga ttaccatgat ttttatagtt gaagaaccta agacacagag
4681 accaaggccc atgagctcat agggctgagg caggatttgg aatcaggcca tgtcttctcc
4741 agagcccaca tccatccttt ctctatattg cctcccacag atgtgctaaa atttatttaa
4801 ctaatccttt atcctctatt tgtgttgtct cccatttttt attattacaa tattactgtg
4861 gtgaacatgc ttaaaaatac attccttgga tatctgacaa cgtgtttctg aaaaacagat
4921 tttcataagt aataataaaa ataataataa aaaagttttg gtatggtaaa aaa
＜110〉Attached Tongji Hospital, Tongji Univ.
＜120〉pulmonary thromboembolism related gene and application thereof
<160>142
<210>109
<211>3949
<212>DNA
＜213〉human (Homo sapiens)
<400>109
1 aggagccgac gggcgctcgc aggctcagcg cgcgctgccc gcggcaggac ccggccgcct
61 ccgccgccgc cgccgcccct aagcctcccg aagccatggc cgggctcggc caccccgccg
121 ccttcggccg ggccacccac gccgtggtgc gggcgctacc cgagtcgctc ggccagcacg
181 cgctgagaag cgccaagggc gaggaggtgg acgtcgcccg cgcggaaggg cagcaccagc
241 tctacgtggg cgtgctgggc agcaagctgg ggctgcaggt ggtggagctg ccggccgacg
301 agagccttcc ggactgcgtc ttcgtggagg acgtggccgt ggtgtgcgag gagacggccc
361 tcatcacccg acccggggcg ccgagccgga ggaaggaggt tgacatgatg aaagaagcat
421 tagaaaaact tcagctcaat atagtagaga tgaaagatga aaatgcaact ttagatggcg
481 gagatgtttt attcacaggc agagaatttt ttgtgggcct ttccaaaagg acaaatcaac
541 gaggtgctga aatcttggct gatactttta aggactatgc agtctccaca gtgccagtgg
601 cagatgggtt gcatttgaag agtttctgca gcatggctgg gcctaacctg atcgcaattg
661 ggtctagtga atctgcacag aaggccctta agatcatgca acagatgagt gaccaccgct
721 acgacaaact cactgtgcct gatgacatag cagcaaactg tatatatcta aatatcccca
781 acaaagggca cgtcttgctg caccgaaccc cggaagagta tccagaaagt gcaaaggttt
841 atgagaaact gaaggactat atgctgatcc ccgtgagcat gtctgaactg gaaaaggtgg
901 atgggctgct cacctgctgc tcagttttaa ttaacaagaa agtagactcc tgagctgcag
961 agtccccccc ggtagccggc aagaccgcac aggcaaggcc gatgactctg tgcccactcc
1021 tgttgttttc cttgacaatc tactgtgcca ctgtgctact aactcttgtt tacaaaattt
1081 gattctaagt tgaattgctt cattcaacac ccccaccctc cctcccctcg aggtggtacc
1141 taagctgtgg atttgctaaa tgaattaagc aacctagaag atacagagct aatgaattat
1201 caaaatgtga ttaatcccag taaggaaaca ctcatttagt gtctgtattt ttggtgtgaa
1261 aattatttag ttgccagtat attctgaaga atgtcttctt gatcagtcag ataagcttgc
1321 tttttttttt tttttttttc atgaatcatg tttggttcct gtgaaagtcc ctggtccagg
1381 gatcctcctc ctttctcttt tacttctgaa ttctgaaatt cagttagtta cttttgcctt
1441 tcgctcttct atcacagcca ccttgacctt gggtaaaacc caaggtcttt ccttctggct
1501 accttcctgc aggtccaccc tgtctgccat tggtctcctc tgcctctgac tacatctgcc
1561 accaacaacc ctcccctcac ccctgccagg ggcagacagg cttctcagca gaactgtgac
1621 tgaaatcaga gctgctgtct ggggcagtgt taactacaca gaggcacatc ctgacagggt
1681 ttgccccaga gatctaaatt ccagaaggag ggcaccacac ctaggaaggt aaatccagta
1741 tcagaaggtt gctaaaagat taaagatcaa gaagcttgga aacatcccat gggtacaatg
1801 tcttagaaag tctttaagtc acataccatg aatttttgct tcattactga ccatatatga
1861 ccttggagga actctttttt ttttttcctt ctactcattt ctgtttccac ctaccctgac
1921 tcaccgtatt tccagtcttc tacccctgca gttatcctag tccagcaaag tcatttcttt
1981 caaaagagac atcatgtctg aaaataatta ctggtagtct aatatgagcc agagtaaaca
2041 gctcctcatg gtcaatgaac atgttcagga agcgatcacc ttgatgcttg aacccaaccc
2101 cagacagtgg acaattctac tttgaaatat ccgtgaatat ttactgtggg atccaattta
2161 aacttctttc ttctctagcc tttaaattac acaactttga actgacacgg atctcttaca
2221 aagaacaatg cggcactgaa ggaagagatg attcctttac tcaaacctgc aggaatcagc
2281 ctattaacag gcaggggaaa cggtactttc caatgaatgg taactgatcc aggcacatta
2341 tcacacttcc tagtcatctc cacctttcct gtattgcctg tggcttgttg tttaagatta
2401 agaatcaaag agattaagaa gtatcacttc aagtcttgct ctgctcactt ctatgtttgc
2461 agtcaaatta ttccttatgt tggtgaccta aagagaatta ctttcattca tttcatttcc
2521 cccgtagcag atggaagtga gaaacctctg agaaaatgaa aacatcctta accactatct
2581 ttccctttta tttgattatt ttatgtcaga aatttgcaaa agtttttttc tcctccttct
2641 cttccttgtt gcttaacttt ttaattcatg ccatatgcag atatccaatt atgtgcatcc
2701 tgtgaataaa ccacgtcttg gtcactgtca tattttgaac catctcatca gagatgaata
2761 atatcttttt accagagaga gaacgaatgt tagccacatg cccaagttaa caaagaaaaa
2821 atgttctcaa ggttgtcctt ttgggttaaa tctggccctt ccttggcaaa agcaaaaatt
2881 ctccctgtga gagctcaaca tctcaaatac aaccacagga aaaatggccc aatctgccag
2941 tttaggctta ccagcatata atttttaata tctttacttc tatcatccca aatcaaagaa
3001 ctcttctcta ttatgtttaa tcaattgcaa gcaaatagat ttttctttgt aacaatttgt
3061 tctgcagaag gctgtttttc acttttcctt tcttttgctt ctttctgtct ttccttctct
3121 tttgtctgga gaaatcactt agactctgtg tgcctcttct acattgcatt ctgctctgct
3181 atgttacctg ctaggctggc ttctttggac tccctatatg attgatgatg tgaaaaccta
3241 aattacttgc agcatagtat tacttctttg atgttctcat tagcataatg ttatttttga
3301 aaaggaaaga tactatcaca taagttttcc tcatctgttg tgatatacac caatggataa
3361 actaacggaa actgcttttt gacattaaaa gacaggagaa attatattta actaagtaaa
3421 agttaagtca gaattacttg ggtgatgtga ttcaatttag ttaaaggatg atatagagaa
3481 aatacattat ttagcattat ttcttcagct ataatgaatt gctatagaaa tcaggcagat
3541 ctttctaatg tgtattgatt ggtcttttca gctactctga acagattact aaggccatct
3601 cctcatctct aagggagaaa aatagtctgt agatgaataa tgtaaggtaa agagttgcat
3661 gtcagtcttt gtaattattt acactttaac tttctccaga actcagacat gatttcaaca
3721 tggtgttaga tttgtgcatt ttattttcct gaccacctca ttccagccaa tgtatggtta
3781 tccactctgt gtgccaaaac caatcatgcc tttcacggcc ctttagttca gagaagttct
3841 gcactgattt ttagtctctt gatgtctcaa tcttacatgt ataccaatca caatggaata
3901 aagtgttgag ttgtactgtg aaaaaaaaaa aaaaaaaaaa aaaaaaaaa
＜110〉Attached Tongji Hospital, Tongji Univ.
＜120〉pulmonary thromboembolism related gene and application thereof
<160>142
<210>110
<211>1351
<212>DNA
＜213〉human (Homo sapiens)
<400>110
1 ccgcttagac aatgccccgg agccgccaga ccgtcgcgcc cctgccccat cgtagtatat
61 gagctcgcct acacaaggac ccccgctaaa agccagagct cccagtcccc gaggcttgaa
121 gacggggact cccttctcca ccaactctgt cctcgggggg tggggcccca gccgagatca
181 cagcgcgaca ggagtggggg tggccgctgg agacaggtga agaaacaaga aaactaagaa
241 atccgagcgg ttggaggggg agtctgtgtg gatgggatgg ggacgccggg ggaggggctg
301 ggccgctgct cccatgccct gatccgggga gtcccagaga gcctggcgtc gggggaaggt
361 gcgggggctg gccttcccgc tctggatctg gccaaagctc aaagggagca cggggtgctg
421 ggaggtaaac tgaggcaacg actggggcta cagctgctag aactgccacc tgaggagtca
481 ttgccgctgg gaccgctgct tggcgacacg gccgtgatcc aaggggacac ggccctaatc
541 acgcggccct ggagccccgc tcgtaggcca gaggtcgatg gagtccgcaa agccctgcaa
601 gacctggggc tccgaattgt ggaaatagga gacgagaacg cgacgctgga tggcactgac
661 gttctcttca ccggccggga gtttttcgta ggcctctcca aatggaccaa tcaccgagga
721 gctgagatcg tggcggacac gttccgggac ttcgccgtct ccactgtgcc agtctcgggt
781 ccctcccacc tgcgcggtct ctgcggcatg gggggacctc gcactgttgt ggcaggcagc
841 agcgacgctg ccgaaaaggc tgtccgggca atggcagtgc tgacagatca cccatatgcc
901 tccctgaccc tcccagatga cgcagctgct gactgcctct ttcttcgtcc tgggttgcct
961 ggtgtgcccc ctttcctcct gcaccgtgga ggtggggatc tgcccaacag ccaggaggca
1021 ctgcagaagc tctctgatgt caccctggta cctgtgtcct gctcagaact ggagaaggct
1081 ggcgccgggc tcagctccct ctgcttggtg ctcagcacac gcccccacag ctgagggcct
1141 ggccttgggg tactgctggc caggggtagg atagtatagg aagtagaagg ggaaggaggg
1201 ttagatagag aatgctgaat aggcagtagt tgggagagag cctcaatatt gggggagggg
1261 agagtgtagg gaaaaggatc cactgggtga atcctccctc tcagaaccaa taaaatagaa
1321 ttgacctttt aaaaaaaaaa aaaaaaaaaa a
＜110〉Attached Tongji Hospital, Tongji Univ.
＜120〉pulmonary thromboembolism related gene and application thereof
<160>142
<210>111
<211>7062
<212>DNA
＜213〉human (Homo sapiens)
<400>111
1 gtgaggccct gccgggtcgg gctgcgggcg gccgggcgcg ggcggcggga cagacgggcg
61 cacgcgagga ctgacggacg gacgcaccga gggcggcggg cacgcacggc ccgggccggc
121 gctccaaggc ccgcccggga gggccggggc cgcgctcaga attttgattt ggctgctggg
181 ctgctacctt gaaatccaag ccctaaaaat gccagcttct ttggacttag aagatgacct
241 ggataaatga taaaaattaa gaaagagatt ttgaagtttt cttattgtcc tcttggcata
301 tgcttctgga ataatattca ccatggtttt ggatgacctt ccaaacttag aagacatcta
361 tacttccttg tgttcatcaa caatggaaga ctcagagatg gattttgact ctggactaga
421 agatgatgac acaaaaagtg atagtatttt ggaggattcc acaatttttg tggccttcaa
481 aggaaatata gatgataaag acttcaaatg gaaattagat gcaatattga aaaacgtgcc
541 caatttgtta cacatggagt ccagcaagct aaaagtacag aaggtggagc cctggaacag
601 cgtgcgtgtg acattcaaca tcccccggga agcagcggag cggctacgga tccttgctca
661 gagcaacaac cagcagcttc gggatttagg gattctctcc gttcagattg aaggggaagg
721 tgctattaac ctggctttgg ctcagaaccg aagccaagat gtgagaatga atggacccat
781 gggagctgga aattcagtta ggatggaggc gggatttcct atggcaagtg gtccaggaat
841 aataaggatg aacaaccctg ccactgttat gatacccccg ggtggaaatg tgtcatcttc
901 catgatggca ccaggcccca atccagagct gcagcccagg actcctcgcc ctgcttctca
961 gtcagatgca atggatccac tcctctctgg gctccatata cagcagcaaa gtcatccctc
1021 aggatcttta gctcccccac atcacccaat gcagcctgtc tctgtgaaca gacaaatgaa
1081 cccagctaat tttccccagc tgcagcagca gcagcaacaa caacaacagc agcagcagca
1141 gcagcagcag caacaacagc aacagcagca acaacagttg caggcaagac ccccacagca
1201 acatcagcag caacagccac agggaattcg accccagttt actgccccaa ctcaggtgcc
1261 tgttcctcca ggctggaacc agctgccttc tggagccctt caacctcctc cagcccaggg
1321 ttctctgggc acaatgactg caaaccaagg gtggaagaag gctcccttgc ccggcccaat
1381 gcaacagcaa ctccaggcaa gaccatcctt agccacggta cagacgcctt cccaccctcc
1441 ccctccatat ccctttggca gccagcaagc ctcacaagcc cacacaaact ttcctcagat
1501 gagcaaccca ggccagttca cagctcctca gatgaagagt ttgcagggag ggccctctag
1561 ggtcccaact cccttgcagc agccccacct caccaacaag tctcctgcct cctcaccctc
1621 ctccttccag cagggatccc ctgcatcctc cccaacggtt aaccaaactc agcagcagat
1681 gggaccaagg ccacctcaaa ataacccact tccccaggga tttcagcagc ctgtcagctc
1741 tccgggtcgg aatcctatgg ttcaacaggg aaatgtgcca cctaacttca tggtgatgca
1801 gcagcaacca ccaaaccagg ggccacagag tttacatcca ggcctaggag gaatgcctaa
1861 acgcctccca cctggcttct cagcaggaca ggccaatccg aactttatgc aaggtcaggt
1921 gccttcgacc acagcaacca cccctgggaa ttcaggagcc cctcagctgc aagcaaatca
1981 aaatgtccag catgcaggtg gtcaaggagc tggtcctcct caaaaccaga tgcaggtgtc
2041 ccacgggccg ccaaatatga tgcagcccag cctcatggga attcatggca acatgaacaa
2101 tcagcaggct ggtacttctg gggttcctca agtgaacctc agcaacatgc aaggccagcc
2161 ccagcagggc ccaccatctc agctgatggg catgcaccag caaatcgtgc cctcccaggg
2221 ccagatggtc cagcaacaag gaaccttgaa ccctcagaac cctatgatcc tttcaagggc
2281 ccagcttatg ccacagggcc agatgatggt gaaccccccg agccaaaatc ttgggccctc
2341 gccccaaagg atgaccccac ccaagcagat gctttcccag cagggcccac aaatgatggc
2401 gccacataac cagatgatgg ggcctcaggg gcaggttttg ctccaacaga acccaatgat
2461 agagcagatt atgaccaatc aaatgcaggg gaataagcag cagtttaaca ctcagaacca
2521 gtccaatgtc atgccgggac cagcccagat aatgagggga ccaactccga acatgcaagg
2581 aaatatggtg cagtttacgg gacagatgtc aggacagatg ctgccccagc aagggcctgt
2641 gaacaacagt ccatctcagg ttatgggcat tcagggacag gtcctgcggc caccagggcc
2701 cagcccacac atggcccagc agcatggtga tcctgctact acagcaaata acgatgtcag
2761 tttatctcag atgatgcctg atgttagcat tcaacaaacc aacatggtcc cccctcatgt
2821 gcaggccatg cagggaaaca gtgcctcggg aaaccacttc tcaggccatg ggatgtcttt
2881 caatgcacct ttcagtggag ctcccaatgg aaatcagatg tcctgtggtc aaaatccagg
2941 cttcccagtc aataaggatg tcacgctaac gagcccattg ttggtcaact tattgcagag
3001 tgacatatct gcaggccatt ttggggtaaa caataagcaa aataatacca acgcaaataa
3061 accgaagaag aagaaacccc ctcggaagaa gaaaaatagt cagcaagatc taaacacccc
3121 agatactcgc ccagctggtc tggaagaggc tgatcagcca ccgttgcctg gagaacaagg
3181 aattaacttg gataactcag gccctaaact gccagaattt tcaaaccggc caccaggtta
3241 tccttctcaa ccagttgaac agaggccact tcagcagatg cctcctcaac tcatgcagca
3301 tgtggcaccc ccaccacagc caccacagca gcagccacag ccacaactgc ctcagcagca
3361 gcagccacca cctcccagtc agccacagtc tcagcagcag cagcagcagc agcaacaaat
3421 gatgatgatg ctcatgatgc agcaggatcc caaatcagtt aggcttccag tctctcaaaa
3481 tgtccatcct ccaaggggcc ccctgaaccc cgactcccag agaatgccca tgcaacagag
3541 tggcagtgtg cctgtcatgg tcagtctgca aggacctgcc tccgtgccac catcacctga
3601 taaacaaaga atgccaatgc ctgtgaatac tcccttggga agcaattcaa ggaaaatggt
3661 ctatcaggag agcccgcaga atccttccag ctcgccactg gcggagatgg cctcactccc
3721 tgaagcaagt ggcagtgaag caccatctgt cccaggaggc ccaaacaaca tgccttcaca
3781 tgtagtactt ccccagaatc agttaatgat gacagggcca aaacctggac catcgcccct
3841 ttcagcaact caaggtgcaa ctccccagca accccctgta aattccctgc ccagctctca
3901 cggccaccac ttcccaaatg tggctgcgcc aacccagaca tctaggccca aaacaccaaa
3961 cagagccagc cccagaccct attatcctca gacacccaac aaccgccctc ccagcacaga
4021 accttcagaa atcagtctgt caccagaaag actcaatgcc tccatagcag gactcttccc
4081 tccacagatt aatattcctt tacctcctag gccaaattta aacaggggct ttgatcaaca
4141 aggcctaaat ccaacaactt tgaaggccat cgggcaagca ccttcaaatc ttaccatgaa
4201 tccttccaat tttgctaccc cacaaactca caaattagat tctgtggtag tgaattctgg
4261 aaagcagtct aattctggag caacaaaacg ggcaagtcca agcaacagtc gcaggtctag
4321 tcctgggtcc agtaggaaaa ccactccaag ccctgggagg caaaattcaa aagcccctaa
4381 acttactctg gcctctcaga caaatgcagc cctattgcag aatgtggagt tgccgagaaa
4441 tgtattggtc agtcccactc ctctggccaa tccccctgta cctgggagc tttcctaacaa
4501 cagtgggctg aatcctcaga attctactgt gtctgtggct gcagttgggg gtgttgttga
4561 ggataacaag gagagcttga atgtgcctca ggacagtgat tgccagaatt cccagagtag
4621 gaaggaacag gtaaacattg aactaaaagc agtccctgcc caagaagtta aaatggttgt
4681 ccctgaagat cagtccaaaa aggatgggca gccttcggat cctaacaaac ttcccagtgt
4741 cgaagagaac aaaaatttgg tgtctcctgc tatgagggaa gcaccaacat cgttaagtca
4801 acttcttgac aactctggag ctcccaatgt gacaattaaa ccccctgggc ttacagatct
4861 ggaagtaaca cctccagtag tttctgggga ggacctcaaa aaagcatctg tcattcccac
4921 actgcaggat ctgtcttctt ctaaagaacc ttctaattcc ctaaacttac ctcacagtaa
4981 tgagctgtgt tcatcccttg tgcatcccga attgagtgag gtcagttcta acgttgcacc
5041 aagcatccct ccagtaatgt caagacctgt tagctcttcc tccatttcca ctcccttgcc
5101 cccaaatcaa ataactgtat ttgtcacttc caatcccatc acaacttcag ctaacacatc
5161 agcagctttg ccaactcact tgcagtctgc attgatgtca acagttgtca caatgcccaa
5221 tgcgggtagc aaggttatgg tttctgaggg acagtcagct gctcagtcta atgcccggcc
5281 tcagttcatt acacctgtct ttatcaattc atcctcaata attcaggtta tgaaaggatc
5341 acagccaagc acaattcctg cagccccact gacaaccaac tctggcctga tgcctccctc
5401 tgttgcagtt gttggccctt tacacatacc tcagaacata aaattttctt ctgctcctgt
5461 accgcctaat gccctctcca gtagtcctgc tccaaacatc cagacaggtc gacctttggt
5521 ccttagctca cgagccaccc ctgttcagct tccttcccct ccttgtacgt cttctccagt
5581 tgtcccttct catccccctg tgcagcaagt gaaagaattg aatccagatg aggctagccc
5641 tcaggtgaac acctcagcag atcagaacac tcttccctct tcacagtcaa ccacaatggt
5701 ttctcccctt ttgaccaata gtccagggtc ctctggcaac cggcgaagcc cagtctcgtc
5761 tagtaagggc aaaggaaaag tggacaaaat tggccaaatt ttgttgacca aggcatgtaa
5821 gaaagttaca ggctctcttg agaaagggga agaacaatat ggtgcagatg gagagactga
5881 aggccaaggg ctagacacca cagctccggg gctcatggga acagagcagt tatccacaga
5941 gctggacagt aaaaccccaa cgcccccagc acccactctg ctaaaaatga cctctagccc
6001 tgtgggcccg ggcactgcct cagcaggacc cagcttacct ggcggtgctc tccccaccag
6061 tgtacgctcg atagtaacca ctctggtacc ctccgagctc atctccgccg taccgaccac
6121 aaaaagcaat catggtggca tagcatctga gtcacttgcg ggtggcctag tggaggagaa
6181 ggtgggatcc catccagaac ttctacccag catagccccg tcgcagaatt tagtctcaaa
6241 ggaaacttca accacagcac tgcaggcctc tgttgccaga ccagagctgg aggtaaatgc
6301 tgccatagtc tctggacaaa gcagtgagcc caaagagata gttgaaaagt ccaaaatccc
6361 aggccgaaga aactcccgaa ctgaagagcc aactgtggcc tctgaaagtg tggaaaatgg
6421 acatcgtaaa cgatcttctc gacctgcttc agcctccagc tctactaaag acataaccag
6481 tgcggtgcaa tccaagcgaa gaaaatccaa gtaaacaagc aggactgcga cttgatactt
6541 ggaaatgtgt gtgactttta caaagagcaa ttttgagctg tgactttttt aaatcaattt
6601 ctgtacagtt agtaatttta ataatgtggc ccttttccta gtccctgcaa cctgtttcat
6661 aaagtgcaat ggggaaagca ggactgttga gcccttttgg tgttgcgagt tgaagttcaa
6721 ggtttctaaa atgttgtctt gtattgaaag gagctaatgc cattataaat gttactagtt
6781 ttcacatttc ctaagcagcc tagagtacag ggtgagcatt tttagatctc ctaatgatgt
6841 attgtgccgt ggaagtactg tgtgtgaata gcagtagtgg gggcaaaagc aatcttctca
6901 tttggaaatg ttgtaaataa ttttattata tagtgttttg gatgtatttg ttgtagaaat
6961 ggaccagtga ataaagagaa tctaaggatt tgtacaatgt gaaataacgt gttaaataaa
7021 tgtcattgtc atagaacata aagttatgtt attggtaagg ga
＜110〉Attached Tongji Hospital, Tongji Univ.
＜120〉pulmonary thromboembolism related gene and application thereof
<160>142
<210>112
<211>2813
<212>DNA
＜213〉human (Homo sapiens)
<400>112
1 atcggagtgt ggcagtgctg ggctggccgg cgggctgggc tgcggcccgc gcgcggccgg
61 cgatgcaggg gggcaactcc ggggtccgca agcgcgaaga ggagggcgac ggggctgggg
121 ctgtggctgc gccgccggcc atcgactttc ccgccgaggg cccggagccc gaatatgacg
181 aatctgatgt tccagcagaa atccaggtgt taaaagaacc cctacaacag ccaaccttcc
241 cttttgcagt tgcaaaccaa ctcttgctgg tttctttgct ggagcacttg agccacgtgc
301 atgaaccaaa cccacttcgt tcaagacagg tgtttaagct actttgccag acgtttatca
361 aaatggggct gctgtcttct ttcacttgta gtgacgagtt tagctcattg agactacatc
421 acaacagagc tattactcac ttaatgaggt ctgctaaaga gagagttcgt caggatcctt
481 gtgaggatat ttctcgtatc cagaaaatca gatcaaggga agtagccttg gaagcacaaa
541 cttcacgtta cttaaatgaa tttgaagaac ttgccatctt aggaaaaggt ggatacggaa
601 gagtatacaa ggtcaggaat aaattagatg gtcagtatta tgcaataaaa aaaatcctga
661 ttaagggtgc aactaaaaca gtttgcatga aggtcctacg ggaagtgaag gtgctggcag
721 gtcttcagca ccccaatatt gttggctatc acaccgcgtg gatagaacat gttcatgtga
781 ttcagccacg agcagacaga gctgccattg agttgccatc tctggaagtg ctctccgacc
841 aggaagagga cagagagcaa tgtggtgtta aaaatgatga aagtagcagc tcatccatta
901 tctttgctga gcccacccca gaaaaagaaa aacgctttgg agaatctgac actgaaaatc
961 agaataacaa gtcggtgaag tacaccacca atttagtcat aagagaatct ggtgaaattg
1021 agtcgaccct ggagctccag gaaaatggct tggctggttt gtctgccagt tcaattgtgg
1081 aacagcagct gccactcagg cgtaattccc acctagagga gagtttcaca tccaccgaag
1141 aatcttccga agaaaatgtc aactttttgg gtcagacaga ggcacagtac cacctgatgc
1201 tgcacatcca gatgcagctg tgtgagctct cgctgtggga ttggatagtc gagagaaaca
1261 agcggggccg ggagtatgtg gacgagtctg cctgtcctta tgttatggcc aatgttgcaa
1321 caaaaatttt tcaagaattg gtagaaggtg tgttttacat acataacatg ggaattgtgc
1381 accgagatct gaagccaaga aatatttttc ttcatggccc tgatcagcaa gtaaaaatag
1441 gagactttgg tctggcctgc acagacatcc tacagaagaa cacagactgg accaacagaa
1501 acgggaagag aacaccaaca catacgtcca gagtgggtac ttgtctgtac gcttcacccg
1561 aacagttgga aggatctgag tatgatgcca agtcagatat gtacagcttg ggtgtggtcc
1621 tgctagagct ctttcagccg tttggaacag aaatggagcg agcagaagtt ctaacaggtt
1681 taagaactgg tcagttgccg gaatccctcc gtaaaaggtg tccagtgcaa gccaagtata
1741 tccagcactt aacgagaagg aactcatcgc agagactatc tgccattcag ctgctgcaga
1801 gtgaactttt ccaaaattct ggaaatgtta acctcaccct acagatgaag ataatagagc
1861 aagaaaaaga aattgcagaa ctaaagaagc agctaaacct cctttctcaa gacaaagggg
1921 tgagggatga cggaaaggat gggggcgtgg gatgaaagtg gacttaactt ttaaggtagt
1981 taactggaat gtaaattttt aatctttatt agggtatagt tggtacaatg cttcgttgta
2041 tttagtaagc ctttacaaga cttgttaaag atgtcagagt gccccaagct gccgttcctt
2101 cccttcctgc cccacaagct ccttttcctg aatttcctac ctaaatatta accatatgcc
2161 tagtctctga aactaaaaac ttggacctca tcctcaatta ttttctcctt tcaactctgt
2221 tgaccctctg tctggtcttc ctctagaagg ttctaccgca gaaattgatg tgtgctccct
2281 gccctcgtca ctgcccaagc ccgggcctgc acatactcac tggactgttc cagttttgac
2341 agctgccagt cttcctgccc ctttcacact gcagctgaag ttcattacct gaaggacgcc
2401 tcatcatttc attccttggc tccaaacctt ctgctgcctc taagataaaa gctcaacttc
2461 ttaacagtgt acagtgtgca acttccaacc tttttatctg ttctctccac cttcagttta
2521 gcgtcattcc aaaaccacac ccttgcaaag ctttgtactc cgcaccccag atgatctcca
2581 ggcagctcag atctctttcc tgcctttgcc ctgcactgtt ccccggtact tcctccttta
2641 ttgtagcact cagctcccca gccaatctgt acatccctca gaggcagcga tctgatgaat
2701 tggtttttga atcccagaaa gggtctgcca tggagttggc agtcatcacg gtagatggcg
2761 tatgattttg ctgaatttta aataaaatga aaaccataaa aaaaaaaaaa aaa
＜110〉Attached Tongji Hospital, Tongji Univ.
＜120〉pulmonary thromboembolism related gene and application thereof
<160>142
<210>113
<211>3682
<212>DNA
＜213〉human (Homo sapiens)
<400>113
1 gaccatcaga ccggcctgaa taccagaatc tctttgcaat gcactcgcct cgctcattac
61 cagaaggagg ttttacctgc ctagtgacct ggttggtctg ggcatgaacc ccgagaggtg
121 gaaactctca gactctcagg actgacagcc gagtggctgg ggactataaa tccgcgagaa
181 ctgccctcgc gctgccatcc agctgggtag ccgggggagc gcgcgtgggg gctccgcgag
241 tcgctcgccc ttggtttctg gggaagcctg ggggacgcgg ctgtggcgga ggcgccctgg
301 gactcaggtc gcctggagcg tggcacgcag agccccaggc gcggagctga ggccgcgcgg
361 ccgcgcttgg ccccagcggg cgtgggactg agcagtctgc tgccccccga catgtgaccc
421 agccccgccg cccatgcggg ctcccggccg cccggccctg cggccgctgc cgctgccgcc
481 gctgctgctg ttgctcctgg cggcgccttg gggacgggca gttccctgtg tctctggtgg
541 tttgcctaaa cctgcaaaca tcaccttctt atccatcaac atgaagaatg tcctacaatg
601 gactccacca gagggtcttc aaggagttaa agttacttac actgtgcagt atttcatata
661 tgggcaaaag aaatggctga ataaatcaga atgcagaaat atcaatagaa cctactgtga
721 tctttctgct gaaacttctg actacgaaca ccagtattat gccaaagtta aggccatttg
781 gggaacaaag tgttccaaat gggctgaaag tggacggttc tatccttttt tagaaacaca
841 aattggccca ccagaggtgg cactgactac agatgagaag tccatttctg ttgtcctgac
901 agctccagag aagtggaaga gaaatccaga agaccttcct gtttccatgc aacaaatata
961 ctccaatctg aagtataacg tgtctgtgtt gaatactaaa tcaaacagaa cgtggtccca
1021 gtgtgtgacc aaccacacgc tggtgctcac ctggctggag ccgaacactc tttactgcgt
1081 acacgtggag tccttcgtcc cagggccccc tcgccgtgct cagccttctg agaagcagtg
1141 tgccaggact ttgaaagatc aatcatcaga gttcaaggct aaaatcatct tctggtatgt
1201 tttgcccgta tctattaccg tgtttctttt ttctgtgatg ggctattcca tctaccgata
1261 tatccacgtt ggcaaagaga aacacccagc aaatttgatt ttgatttatg gaaatgaatt
1321 tgacaaaaga ttctttgtgc ctgctgaaaa aatcgtgatt aactttatca ccctcaatat
1381 ctcggatgat tctaaaattt ctcatcagga tatgagttta ctgggaaaaa gcagtgatgt
1441 atccagcctt aatgatcctc agcccagcgg gaacctgagg ccccctcagg aggaagagga
1501 ggtgaaacat ttagggtatg cttcgcattt gatggaaatt ttttgtgact ctgaagaaaa
1561 cacggaaggt acttctctca cccagcaaga gtccctcagc agaacaatac ccccggataa
1621 aacagtcatt gaatatgaat atgatgtcag aaccactgac atttgtgcgg ggcctgaaga
1681 gcaggagctc agtttgcagg aggaggtgtc cacacaagga acattattgg agtcgcaggc
1741 agcgttggca gtcttgggcc cgcaaacgtt acagtactca tacacccctc agctccaaga
1801 cttagacccc ctggcgcagg agcacacaga ctcggaggag gggccggagg aagagccatc
1861 gacgaccctg gtcgactggg atccccaaac tggcaggctg tgtattcctt cgctgtccag
1921 cttcgaccag gattcagagg gctgcgagcc ttctgagggg gatgggctcg gagaggaggg
1981 tcttctatct agactctatg aggagccggc tccagacagg ccaccaggag aaaatgaaac
2041 ctatctcatg caattcatgg aggaatgggg gttatatgtg cagatggaaa actgatgcca
2101 acacttcctt ttgccttttg tttcctgtgc aaacaagtga gtcacccctt tgatcccagc
2161 cataaagtac ctgggatgaa agaagttttt tccagtttgt cagtgtctgt gagaattact
2221 tatttctttt ctctattctc atagcacgtg tgtgattggt tcatgcatgt aggtctctta
2281 acaatgatgg tgggcctctg gagtccaggg gctggccggt tgttctatgc agagaaagca
2341 gtcaataaat gtttgccaga ctgggtgcag aatttattca ggtgggtgta ctctggcctc
2401 ttggttcatt attttcaaac aagcacactt gtacaattat tttctgggta cttcccatat
2461 gcacatagca ctgtaaaaaa tatttcccaa agatcactca ttttataaat accacttttt
2521 cagaattggg tttattgcga gcaggaggag atacttaaaa catgcacata taccaggttg
2581 gtggtaagtt ggtcgcatgt gaaaacctca actatttaat catcatgatt catattttga
2641 gtgaatacat caggcacaga ccttcatgat atcacacact cttggctact ttaagaggcc
2701 atctttaata ctttatgagt agttctggag tgtaaacata aacgagtatt cttttgtagt
2761 cagaaaagtg tcctctcaat aatttagtag gggcttattg tctctcaaaa ctaacctaaa
2821 agaaaatgac acattttata atagaatatt acatttattt ctggaagtgt gttttcaaaa
2881 agatatttac atagtctgta aactagaaag tgttaggtaa agctctaggt tactgtgtta
2941 ctattataat attaaacatt cgaataggca gtcgttcaaa gactctttgg aatatctatg
3001 aatgaatatc ctctattctt ataatattaa aacccataag taaatatagg acatacaaga
3061 gaaatgagtt aaatgactat gtaagggaga gtttattaaa atttgatgaa atttactgta
3121 ggaactaaac tatgccataa aacaatagct ttctagttca tttccagtaa ctgttcccat
3181 ctcctttacc acttgttaag aaaattaaat tcttcagtca cgctgcttta aaatgggaca
3241 aaatctatta agttgaacca tatataattg tggatatttg gctgttttta atctgacaag
3301 cagtaacttc atatggtttg ccttaatata tatttgtttt agtcatgaac tcataatcca
3361 ttgatgctct ttcatgagaa gagatatcac ccatatttcc ttattgatat tattggtaca
3421 ggcagacaac cctggtagga gagatggatt ctggggtcat gacctttcgt gattatccgc
3481 aaatgcaaac agtttcagat ctaatggttt aatttaggga gtaattatat taatcagagt
3541 gttctgttat tctcaatctt tatagaaacg attctgctgg ttttgaagaa cagatgtatt
3601 acactaactg taaaagtagt tcaagagtga gaaagaataa attgttatta agagcaaaag
3661 aaaaataaag tgattgatga ta
＜110〉Attached Tongji Hospital, Tongji Univ.
＜120〉pulmonary thromboembolism related gene and application thereof
<160>142
<210>114
<211>2617
<212>DNA
＜213〉human (Homo sapiens)
<400>114
1 gcgtccccct cggcgggctg ccgccgtgcc cgcgccggct ccccagcccg agcctgcccc
61 ttgccctgat gaggtgcaaa gagcgggatc ggaggcgggg cctggccggg ctgtgagcgg
121 cgtatgcaaa tcgagggtct cggggatgcg gatccaagac cctgggaagg tcttctttgg
181 caatgtggat tcatctggga taaaacacaa tatttttaac cctccaatta ttgctcgata
241 catccgtttg cacccaactc attatagcat tcgcagcact cttcgcatgg agttgatggg
301 ctgtgattta aatagttgca gcatgccatt gggaatggag agtaaagcaa tatcagatgc
361 acagattact gcttcatcct actttaccaa tatgtttgcc acctggtctc cttcaaaagc
421 tcgacttcac ctccaaggga ggagtaatgc ctggagacct caggtgaata atccaaaaga
481 gtggctgcaa gtggacttcc agaagacaat gaaagtcaca ggagtaacta ctcagggagt
541 aaaatctctg cttaccagca tgtatgtgaa ggagttcctc atctccagca gtcaagatgg
601 ccatcagtgg actctctttt ttcagaatgg caaagtaaag gtttttcagg gaaatcaaga
661 ctccttcaca cctgtggtga actctctaga cccaccgtta ctgactcgct accttcgaat
721 tcacccccag agttgggtgc accagattgc cctgaggatg gaggttctgg gctgcgaggc
781 acaggacctc tactgagggt ggccactgca gcacctgcca ctgccgtcac ctctccctcc
841 tcagctccag ggcagtgtcc ctccctggct tgccttctac ctttgtgcta aatcctagca
901 gacactgcct tgaagcctcc tgaattaact atcatcagtc ctgcatttct ttggtggggg
961 gccaggaggg tgcatccaat ttaacttaac tcttacctat tttctgcagc tgctcccaga
1021 ttactccttc cttccaatat aactaggcaa aaagaagtga ggagaaacct gcatgaaagc
1081 attcttccct gaaaagttag gcctctcaga gtcaccactt cctctgttgt agaaaaacta
1141 tgtgatgaaa ctttgaaaaa gatatttatg atgttaacat ttcaggttaa gcctcatacg
1201 tttaaaataa aactctcagt tgtttattat cctgatcaag catggaacaa agcatgtttc
1261 aggatcagat caatacaatc ttggagtcaa aaggcaaatc atttggacaa tctgcaaaat
1321 ggagagaata caataactac tacagtaaag tctgtttctg cttccttaca catagatata
1381 attatgttat ttagtcatta tgaggggcac attcttatct ccaaaactag cattcttaaa
1441 ctgagaatta tagatggggt tcaagaatcc ctaagtcccc tgaaattata taaggcattc
1501 tgtataaatg caaatgtgca tttttctgac gagtgtccat agatataaag ccatttggtc
1561 ttaattctga ccaataaaaa aataagtcag gaggatgcaa ttgttgaaag ctttgaaata
1621 aaataacaat gtcttcttga aatttgtgat ggccaagaaa gaaaatgatg atgacattag
1681 gcttctaaag gacatacatt taatatttct gtggaaatat gaggaaaatc catggttatc
1741 tgagatagga gatacaaact ttgtaattct aataatgcac tcagtttact ctctccctct
1801 actaatttcc tgctgaaaat aacacaacaa aaatgtaaca ggggaaatta tataccgtga
1861 ctgaaaacta gagtcctact tacatagttg aaatatcaag gaggtcagaa gaaaattgga
1921 ctggtgaaaa cagaaaaaac actccagtct gccatatcac cacacaatag gatccccctt
1981 cttgccctcc acccccataa gattgtgaag ggtttactgc tccttccatc tgcctgaccc
2041 cttcactatg actacacaga atctcctgat agtaaagggg gctggaggca aggataagtt
2101 atagagcagt tggaggaagc atccaaagat tgcaacccag ggcaaatgga aaacaggaga
2161 tcctaatatg aaagaaaaat ggatcccaat ctgagaaaag gcaaaagaat ggctactttt
2221 ttctatgctg gagtattttc taataatcct gcttgaccct tatctgacct ctttggaaac
2281 tataacatag ctgtcacagt atagtcacaa tccacaaatg atgcaggtgc aaatggttta
2341 tagccctgtg aagttcttaa agtttagagg ctaacttaca gaaatgaata agttgttttg
2401 ttttatagcc cggtagagga gttaaccgca aaggtgatat ggttttactt cctgttatgt
2461 ttaacttgat aatcttattt tggcattctt ttcccattga ctatatacat ctctatttct
2521 caaatgttca tggaactagc tcttttattt tcctgctggt ttcttcagta atgagttaaa
2581 taaaacattg acacatacaa acaaaaaaaa aaaaaaa
＜110〉Attached Tongji Hospital, Tongji Univ.
＜120〉pulmonary thromboembolism related gene and application thereof
<160>142
<210>115
<211>1567
<212>DNA
＜213〉human (Homo sapiens)
<400>115
1 cgccccaccc gcgagccgca gccgcggccc cacagcttct ggggctgggg ccccggcagc
61 cgggcaggcc ggcctgacct cgacctccgc cgtgcgggcc cgaccggtga gtccagcccg
121 gcagtcgcag gacccggccg ccagcctctc cctccacctc tccctgcccc cagcgccagg
181 cgcgggctgc gctcggtggc ggcggcgggg ccctcaggcg gccatggcgg caggcgccgg
241 ggccgggtcc gcgccgcgct ggctgagggc gctgagcgag ccgctgagcg cggcgcagct
301 gcggcgactg gaggagcacc gctacagcgc ggcgggcgtc tcgctgctcg agccgccgct
361 gcagctctac tggacctggc tgctccagtg gatcccgctc tggatggccc ccaactccat
421 caccctgctg gggctcgccg tcaacgtggt caccacgctc gtgctcatct cctactgtcc
481 cacggccacc gaagaggcac catactggac atacctttta tgtgcactgg gactttttat
541 ttaccagtca ctggatgcta ttgatgggaa acaagccaga agaacaaact cttgttcccc
601 tttaggggag ctctttgacc atggctgtga ctctctttcc acagtattta tggcagtggg
661 agcttcaatt gccgctcgct taggaactta tcctgactgg ttttttttct gctcttttat
721 tgggatgttt gtgttttatt gcgctcattg gcagacttat gtttcaggca tgttgagatt
781 tggaaaagtg gatgtaactg aaattcagat agctttagtg attgtctttg tgttgtctgc
841 atttggagga gcaacaatgt gggactatac gattcctatt ctagaaataa aattgaagat
901 ccttccagtt cttggatttc taggtggagt aatattttcc tgttcaaatt atttccatgt
961 tatcctccat ggtggtgttg gcaagaatgg atccactata gcaggcacca gtgtcttgtc
1021 acctggactc cacataggac taattattat actggcaata atgatctata aaaagtcagc
1081 aactgatgtg tttgaaaagc atccttgtct ttatatccta atgtttggat gtgtctttgc
1141 taaagtctca caaaaattag tggtagctca catgaccaaa agtgaactat atcttcaaga
1201 cactgtcttt ttggggccag gtcttttgtt tttagaccag tactttaata actttataga
1261 cgaatatgtt gttctatgga tggcaatggt gatttcttca tttgatatgg tgatatactt
1321 tagtgctttg tgcctgcaaa tttcaagaca ccttcatcta aatatattca agactgcatg
1381 tcatcaagca cctgaacagg ttcaagttct ttcttcaaag agtcatcaga ataacatgga
1441 ttgaagagac ttccgaacac ttgctatctc ttgctgctgc tgtttcatgg aaggagatat
1501 taaacatttg tttaattttt atttaagtgt tatacctatt tcagcaaata aaatatttca
1561 ttgctta
＜110〉Attached Tongji Hospital, Tongji Univ.
＜120〉pulmonary thromboembolism related gene and application thereof
<160>142
<210>116
<211>3206
<212>DNA
＜213〉human (Homo sapiens)
<400>116
1 gtttataact tgaaaaatcc tctccgtctc ccttccctgc ctcctttcct ttccctttcc
61 tctgccagta caactagacc cggcgtctgg cgtccccggt gcccagcatt ctgcggggca
121 ggcggattaa ttggaattct tcaaaatgtc aggtgtggta cccacagccc ctgaacagcc
181 tgcaggtgaa atggaaaatc aaacaaaacc accagatcca aggcctgatg ctcctcctga
241 atacagttct cattttttac caggaccccc tggaacagct gtccctccac ctactggcta
301 cccaggaggc ttgcctatgg gatactacag tccacagcaa cccagtacct tccctttgta
361 ccagccagtt ggtggtatcc atcctgtccg gtatcagcct ggcaaatatc ctatgccaaa
421 tcagtctgtt ccaataacat ggatgccagg gccaactcct atggcaaact gccctcctgg
481 tctggaatac ttagttcagt tggacaacat acatgttctt cagcattttg agcctctgga
541 aatgatgaca tgttttgaaa ctaataatag atatgatatt aaaaacaact cagaccagat
601 ggtttacgtt gtaaccgaag acacagatga ctttaccagg aatgcctatc ggacactaag
661 gcccttcgtc ctccgggtca ctgattgtat gggccgagaa atcatgacaa tgcagagacc
721 cttcagatgc acctgctgtt gcttctgttg cccctctgcc agacaagagc tggaggtgca
781 gtgtcctcct ggtgtcacca ttggctttgt tgcggaacat tggaacctgt gcagggcggt
841 gtacagcatc caaaatgaga agaaagaaaa tgtgatgaga gttcgtgggc catgctcaac
901 ctatggctgt ggttcagatt ctgtttttga ggtcaaatcc cttgatggca tatccaacat
961 cggcagtatt atccggaagt ggaatggttt gttatcagca atggcagatg ctgaccattt
1021 tgacattcac ttcccactag acctggatgt gaagatgaaa gccatgattt ttggagcttg
1081 cttcctcatt gacttcatgt attttgaaag atctccacca caacgttcaa gatagagaga
1141 cacagcaagc catcaactat ggttaatttt gaaaaatgga aaagttggat tgggcttaca
1201 gtcagcactc agttatttgc aagtgtattt ctttgctttg tagagtattt ttattgggtg
1261 ttaactttga cagctgagag tgggcttgca agaacacaat ctaaaagtgt gtttcaattg
1321 agtatctctc tagtagaata ggagttcatc ctgaaaagct gtgactcatt aacccagtaa
1381 acatatacaa agtaagctta aaacactata aacatgagat aagggaaaat gaatccagag
1441 ttctcatatt aataggtagt gaaacaataa ggctttttag agcagacttt gttggcataa
1501 aataacctgg cttctatccc taaccctttc ctacctttcc tctccgtcaa catgtcctca
1561 tactgaagac aaacttgttt caatgatagt cttcattttt aaaaacaaaa aggcaggcag
1621 acagaaataa tgatgttttc ttgcactaag aaggtactac ttgtacacat atatcaaaac
1681 ctcattctgc aaagtttttg aaggtttcaa tgggaaattt gattttatta caaaataaaa
1741 cattttttaa tgttaaagtt tatatattcc atgcttgttt tctcattcac tggcatggat
1801 gatcaggagc tgcctatata tgaaggcaga atcagactat caggaaagga gctggccagg
1861 gccacagcca gtcaagatct ctgagcaact tagagacatt ggtgtcatta tatgaagctt
1921 gcatttaata catttataca taatacattt gtacatttaa ttcataacgt ctcttggtca
1981 cagatgcctt atatataaaa taagttgcca gatctctaag attgcctagt acacctttgt
2041 atctcatttg atgtgatacc cagaagagat cattgttttt tgtttttgtt tttgtttttt
2101 tcaagaagat ccttcgtgat caccatgctg ttctcatggt aagaactgga gttatgtttt
2161 taaatttgaa aatatgacat tttatgtagc actatataaa aagtgaaagc gacaaattcc
2221 accgctgctt aatactgctt tgcttctttt tattgacatg atagatacat atgtatctac
2281 acagagtaat aataataaaa cacagtaaac attctatttc tctatggtct acagcatgcc
2341 agtaaataat atgtaggacc aataataaat tatcaattac acatttttgt gttaactaat
2401 taaaagcata gtgtataagt gagtacactc taattaactt gcttctgttg cactttagtt
2461 ttctacctgc atatggactg catttttttt tttaacacag tcagtatgta gaatgggatg
2521 tattcttctg ctgctgctta ttaaataaag aaagcctgag tgttcttaga tggggttatt
2581 ctgagatgag ggtcttagcc tacagttctt tttgaaatga aaggtgcttt gttttttaat
2641 tatattcatc ttttcagggt aaatttgttt ttctgagttt ctcgtaatgc tcatttttac
2701 atgctgctac tagctttttt ttttaaaaaa agtaaaagtt gctgctttct aaaatattaa
2761 ttgccttata tttgaaagtg ccattgcaat cgtaagtaga ctatgtattt cctataatga
2821 tgtctgatat ttaaatagga aatcagacaa acaatattca gaaagtttaa gcatataaac
2881 tttttatttt taacttgcct agatccctgt attccaaaac ctgctgcatc ataataaata
2941 tatctatata tatttagcat aagacgtgat atttttaatt tcttttttaa aaaattatat
3001 ttgtctctta gagttaaaat tttctttata taatattgtc atatgtcata gttttaatac
3061 aattcacatg atttctatgt ttcttaatga tattttgttg tgtaaaattg atcggattga
3121 ttaaaaaaca aattctctgg aatttgtgcg ttcatgcttt ttcgtattct ttatggcttt
3181 taaataaata tacaatggtt aatagt
＜110〉Attached Tongji Hospital, Tongji Univ.
＜120〉pulmonary thromboembolism related gene and application thereof
<160>142
<210>117
<211>5156
<212>DNA
＜213〉human (Homo sapiens)
<400>117
1 gagaggcggg ggattggtat gcgagcgaat gtgcgagggg agggaggcgt cccggcggag
61 cgtggtacta cgaccagcgc gggccggagg gggcgggggg atgcgccgcg gcggcggcgg
121 cgcgggagct ggggttggtg tttggcggcg ccagagcagc ggatcccggt ctcgccgcag
181 cagcagcgcg ggtgtcgtgc accgcctgaa gacgccgtac ctttctaccc tcccaccttt
241 tttttttttt ttttaaataa ccggaaccaa tgaacgcagc cgggatcaga gctccggagg
301 ccgccggtgc cgatgggacc aggctggcgc ccggcgggag cccgtgtctg aggcggcggg
361 ggcggccgga ggagtcgccg gcggcggtgg tggcgcctcg cggagccggc gagctgcagg
421 cggccggggc gccgctgcgc tttcacccgg cttctcctcg gcgccttcat cccgcctcga
481 ctcctggccc agcgtggggc tggctgctgc ggcggcggcg ctgggctgcg ttgctggtgc
541 tcgggctgct ggtagccgga gcggcggacg gatgcgagct tgtgccccgg cacctccgcg
601 ggcggcgggc gactggctct gccgcaactg ccgcctcctc tcccgccgcg gcggccggcg
661 atagcccggc gctcatgaca gatccctgca tgtcactgag tccaccatgc tttacagaag
721 aagacagatt tagtctggaa gctcttcaaa caatacataa acaaatggat gatgacaaag
781 atggtggaat tgaagtagag gaaagtgatg aattcatcag agaagatatg aaatataaag
841 atgctactaa taaacacagc catctgcaca gagaagataa acatataacg attgaggatt
901 tatggaaacg atggaaaaca tcagaagttc ataattggac ccttgaagac actcttcagt
961 ggttgataga gtttgttgaa ctaccccaat atgagaagaa ttttagagac aacaatgtca
1021 aaggaacgac acttcccagg atagcagtgc acgaaccttc atttatgatc tcccagttga
1081 aaatcagtga ccggagtcac agacaaaaac ttcagctcaa ggcattggat gtggttttgt
1141 ttggacctct aacacgccca cctcataact ggatgaaaga ttttatcctc acagtttcta
1201 tagtaattgg tgttggaggc tgctggtttg cttatacgca gaataagaca tcaaaagaac
1261 atgttgcaaa aatgatgaaa gatttagaga gcttacaaac tgcagagcaa agtctaatgg
1321 acttacaaga gaggcttgaa aaggcacagg aagaaaacag aaatgttgct gtagaaaagc
1381 aaaatttaga gcgcaaaatg atggatgaaa tcaattatgc aaaggaggag gcttgtcggc
1441 tgagagagct aagggaggga gctgaatgtg aattgagtag acgtcagtat gcagaacagg
1501 aattggaaca ggttcgcatg gctctgaaaa aggccgaaaa agaatttgaa ctgagaagca
1561 gttggtctgt tccagatgca cttcagaaat ggcttcagtt aacacatgaa gtagaagtgc
1621 aatactacaa tattaaaaga caaaacgctg aaatgcagct agctattgct aaagatgagg
1681 cagaaaaaat taaaaagaag agaagcacag tctttgggac tctgcacgtt gcacacagct
1741 cctccctaga tgaggtagac cacaaaattc tggaagcaaa gaaagctctc tctgagttga
1801 caacttgttt acgagaacga ctttttcgct ggcaacaaat tgagaagatc tgtggctttc
1861 agatagccca taactcagga ctccccagcc tgacctcttc cctttattct gatcacagct
1921 gggtggtgat gcccagagtc tccattccac cctatccaat tgctggagga gttgatgact
1981 tagatgaaga cacaccccca atagtgtcac aatttcccgg gaccatggct aaacctcctg
2041 gatcattagc cagaagcagc agcctgtgcc gttcacgccg cagcattgtg ccgtcctcgc
2101 ctcagcctca gcgagctcag cttgctccac acgcccccca cccgtcacac cctcggcacc
2161 ctcaccaccc gcaacacaca ccacactcct tgccttcccc tgatccagat atcctctcag
2221 tgtcaagttg ccctgcgctt tatcgaaatg aagaggagga agaggccatt tacttctctg
2281 ctgaaaagca atgggaagtg ccagacacag cttcagaatg tgactcctta aattcttcca
2341 ttggaaggaa acagtctcct cctttaagcc tcgagatata ccaaacatta tctccgcgaa
2401 agatatcaag agatgaggtg tccctagagg attcctcccg aggggattcg cctgtaactg
2461 tggatgtgtc ttggggttct cccgactgtg taggtctgac agaaactaag agtatgatct
2521 tcagtcctgc aagcaaagtg tacaatggca ttttggagaa atcctgtagc atgaaccagc
2581 tttccagtgg catcccggtg cctaaacctc gccacacatc atgttcctca gctggcaacg
2641 acagtaaacc agttcaggaa gccccaagtg ttgccagaat aagcagcatc ccacatgacc
2701 tttgtcataa tggagagaaa agcaaaaagc catcaaaaat caaaagcctt tttaagaaga
2761 aatctaagtg aactggctga cttgatggaa tcatgttcaa gtggcatctg taaactatta
2821 tcccccaccc tccactcccc accttttttt tggtttaatt ttaggaatgt aactccattg
2881 gggctttcca ggccggatgc catagtggaa catccagaag ggcaactgtc tactgtctgc
2941 ttatttaagt gactatatat aatcaattca tcaagccagt tattactgaa aaatcattga
3001 aatgagacag tttacagtca tttctgccta tttatttctg ctttgttctc agtgatgtat
3061 atgcaacatt ttgttgaaag ccacgatgga cttacaagct ttaatggact cgtaagccag
3121 catgggcttg caaaaatttc ttgtttacca gagcatcttc ttatctttcc acagagctat
3181 ttacatcctg gactatataa cttaaaagaa gtaaaacgta attgcactac tgttttccag
3241 actggaaaaa aaaaaaatct ctgcaagtga aactgtatag agtttataaa atgactatgg
3301 ataggggact gttttcactt ttagatcaaa atgggttttt aagtagaacc tagggtttct
3361 aattgacttg atttctggaa atgaaaaccc gcgcttttat tatgggaagc ttcttgaact
3421 gcatttacta ttgtgaagtt tcaagtcccg ctgtaaagat catgttgttt tgttttcccc
3481 agggctttca ctgtgattta ctgcattgca ggctgtatga taaaacacac ataatttaaa
3541 gagagaaggc tcttgattcc ttatgcaagt ggaagagttg aaacttgatt gaaggactta
3601 aaacattcac aaccttaagc cgaggtgggg ggatatgggg attcaggcaa ttgtttacac
3661 actttgaata actgcaaagg atttacggtt tgtgaaaaat gtgtactgtg gaaaagataa
3721 taaattgaag acattattgt gtgggattgt gctgattttt gttgataaca caaaaaacac
3781 tatgttttct ggagagctgt gtaagctgtc ttgttgctta gttgcaatat aagaaatagt
3841 gatgttttgg acgtaagttg tcaacaaatt tctattttat attgttatat ttttatgtag
3901 tttgaaatgt aaaaatgttc taatatcaag attaacaaat ataaatttat ggtgcattta
3961 gattgcgttg tattaattta taaagtatgg tgttcattaa attggtgggt tgtataaggg
4021 tagcttttgt tgttaaaaaa acagtagaga gttaagttcc atatagcaac aaagtatgtt
4081 aacatctagg gagtttctgc ttataccact ttaaaaatat gcaatcataa gtgatttggt
4141 tactgcaatg cagatggatg tttggatgaa caactgatac attttagtta gaatgctttt
4201 tcagcattat ggctaaaata tatgtctaac ccagtgctat ttaggtgaaa atgctaattg
4261 ataaaccaga agtttctttt gagatttgct ttaaagaaat gctttagtaa gaatatgaac
4321 aatttcctga tgtctcctat aaattgtgat tgtttattct attactattg ttaaaaactt
4381 gaatggtatt tatattggct gatatttata tacttaatag attgagttct gtaagggcaa
4441 aaacggattg aaatgaacat agcgttttgc actaatgata agataacctg agaggtaggg
4501 ttgaggaaca cagggttgaa agctgttgga gaggggaaaa gttgtgcata aagaactgaa
4561 aagggttctg gagtgttcat tcagagtgaa gggaaaactt tatccttcta tttcttataa
4621 ccagacagga ggagttcttc cctttgaaaa ttgcaaaagg aatgagaact ttgcagttgg
4681 atgaatagag aagggaaaag ttgctggagc acggagtgaa gatgggagga gctgttagca
4741 aggcccactg ctgctcctgg gtgagaaggg agctctggag caggactagc tgggggccgg
4801 cactgctgct tagagtggag gaggctggcc aaagagactg tgggctgttt tcagtcaggg
4861 agcatgtgca ttgtttgtgc tcaatttcag acactcattt ataaacaaat tcaaccaagg
4921 gatatttact gctttatgtt gcttatgata attattttgc attaatacag tatacacatt
4981 tgtaaattca acaggaaatt attgagtttt ggaaagctac agtaatttct gtattacatc
5041 atttatatgt gaaaagttgg acatttctgt aagtttttaa aattatccat ttgttacttt
5101 aacattttaa aattatggtg ttttcctgat tttaaaagca atattttcct tactgt
＜110〉Attached Tongji Hospital, Tongji Univ.
＜120〉pulmonary thromboembolism related gene and application thereof
<160>142
<210>118
<211>2280
<212>DNA
＜213〉human (Homo sapiens)
<400>118
1 tccagccaga aggatggggt ggctcccact cctgctgctt ctgactcaat gcttaggggt
61 ccctgggcag cgctcgcgat tgaatgactt ccaagtgctc cggggcacag agctacagca
121 cctgctacat gcggtggtgc ccgggccttg gcaggaggat gtggcagatg ctgaagagtg
181 tgctggtcgc tgtgggccct taatggactg ccgggccttc cactacaacg tgagcagcca
241 tggttgccaa ctgctgccat ggactcaaca ctcgccccac acgaggctgc ggcgttctgg
301 gcgctgtgac ctcttccaga agaaagacta cgtacggacc tgcatcatga acaatggggt
361 tgggtaccgg ggcaccatgg ccacgaccgt gggtggcctg ccctgccagg cttggagcca
421 caagttcccg aatgatcaca agtacacgcc cactctccgg aatggcctgg aagagaactt
481 ctgccgtaac cctgatggcg accccggagg tccttggtgc tacacaacag accctgctgt
541 gcgcttccag agctgcggca tcaaatcctg ccgggaggcc gcgtgtgtct ggtgcaatgg
601 cgaggaatac cgcggcgcgg tagaccgcac ggagtcaggg cgcgagtgcc agcgctggga
661 tcttcagcac ccgcaccagc accccttcga gccgggcaag ttcctcgacc aaggtctgga
721 cgacaactat tgccggaatc ctgacggctc cgagcggcca tggtgctaca ctacggatcc
781 gcagatcgag cgagagttct gtgacctccc ccgctgcggg tccgaggcac agccccgcca
841 agaggccaca actgtcagct gcttccgcgg gaagggtgag ggctaccggg gcacagccaa
901 taccaccact gcgggcgtac cttgccagcg ttgggacgcg caaatccctc atcagcaccg
961 atttacgcca gaaaaatacg cgtgcaaaga ccttcgggag aacttctgcc ggaaccccga
1021 cggctcagag gcgccctggt gcttcacact gcggcccggc atgcgcgcgg ccttttgcta
1081 ccagatccgg cgttgtacag acgacgtgcg gccccaggac tgctaccacg gcgcagggga
1141 gcagtaccgc ggcacggtca gcaagacccg caagggtgtc cagtgccagc gctggtccgc
1201 tgagacgccg cacaagccgc agttcacgtt tacctccgaa ccgcatgcac aactggagga
1261 gaacttctgc cggaacccag atggggatag ccatgggccc tggtgctaca cgatggaccc
1321 aaggacccca ttcgactact gtgccctgcg acgctgcgct gatgaccagc cgccatcaat
1381 cctggacccc ccagaccagg tgcagtttga gaagtgtggc aagagggtgg atcggctgga
1441 tcagcggcgt tccaagctgc gcgtggttgg gggccatccg ggcaactcac cctggacagt
1501 cagcttgcgg aatcggcagg gccagcattt ctgcgggggg tctctagtga aggagcagtg
1561 gatactgact gcccggcagt gcttctcctc ctgccatatg cctctcacgg gctatgaggt
1621 atggttgggc accctgttcc agaacccaca gcatggagag ccaagcctac agcgggtccc
1681 agtagccaag atggtgtgtg ggccctcagg ctcccagctt gtcctgctca agctggagag
1741 atctgtgacc ctgaaccagc gtgtggccct gatctgcctg ccccctgaat ggtatgtggt
1801 gcctccaggg accaagtgtg agattgcagg ctggggtgag accaaaggta cgggtaatga
1861 cacagtccta aatgtggcct tgctgaatgt catctctaac caggagtgta acatcaagca
1921 ccgaggacgt gtgcgggaga gtgagatgtg cactgaggga ctgttggccc ctgtgggggc
1981 ctgtgagggt gactacgggg gcccacttgc ctgctttacc cacaactgct gggtcctgga
2041 aggaattata atccccaacc gagtatgcgc aaggtcccgc tggccagctg tcttcacgcg
2101 tgtctctgtg tttgtggact ggattcacaa ggtcatgaga ctgggttagg cccagccttg
2161 atgccatatg ccttggggag gacaaaactt cttgtcagac ataaagccat gtttcctctt
2221 taaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaataaaaaa aaaaaaaaaa aaaaaaaaaa
＜110〉Attached Tongji Hospital, Tongji Univ.
＜120〉pulmonary thromboembolism related gene and application thereof
<160>142
<210>119
<211>2077
<212>DNA
＜213〉human (Homo sapiens)
<400>119
1 ccgagcgcca gcgcggggaa ccgggaaaag gaaaccgtgt tgtgtacgta agattcagga
61 aacgaaacca ggagccgcgg gtgttggcgc aaaggttact cccagaccct tttccggctg
121 acttctgaga aggttgcgca cagctgtgcc cggcagtcta gaggcgcaga agaggaagcc
181 atcgcctggc cccggctctc tggaccttgt ctcgctcggg agcggaaaca gcggcagcca
241 gagaactgtt ttaatcatgg acaaacaaaa ctcacagatg aatgcttctc acccggaaac
301 aaacttgcca gttgggtatc ctcctcagta tccaccgaca gcattccaag gacctccagg
361 atatagtggc taccctgggc cccaggtcag ctacccaccc ccaccagccg gccattcagg
421 tcctggccca gctggctttc ctgtcccaaa tcagccagtg tataatcagc cagtatataa
481 tcagccagtt ggagctgcag gggtaccatg gatgccagcg ccacagcctc cattaaactg
541 tccacctgga ttagaatatt taagtcagat agatcagata ctgattcatc agcaaattga
601 acttctggaa gttttaacag gttttgaaac taataacaaa tatgaaatta agaacagctt
661 tggacagagg gtttactttg cagcggaaga tactgattgc tgtacccgaa attgctgtgg
721 gccatctaga ccttttacct tgaggattat tgataatatg ggtcaagaag tcataactct
781 ggagagacca ctaagatgta gcagctgttg ttgtccctgc tgccttcagg agatagaaat
841 ccaagctcct cctggtgtac caataggtta tgttattcag acttggcacc catgtctacc
901 aaagtttaca attcaaaatg agaaaagaga ggatgtacta aaaataagtg gtccatgtgt
961 tgtgtgcagc tgttgtggag atgttgattt tgagattaaa tctcttgatg aacagtgtgt
1021 ggttggcaaa atttccaagc actggactgg aattttgaga gaggcattta cagacgctga
1081 taactttgga atccagttcc ctttagacct tgatgttaaa atgaaagctg taatgattgg
1141 tgcctgtttc ctcattgact tcatgttttt tgaaagcact ggcagccagg aacaaaaatc
1201 aggagtgtgg tagtggatta gtgaaagtct cctcaggaaa tctgaagtct gtatattgat
1261 tgagactatc taaactcata cctgtatgaa ttaagctgta aggcctgtag ctctggttgt
1321 atacttttgc ttttcaaatt atagtttatc ttctgtataa ctgatttata aaggtttttg
1381 tacatttttt aatactcatt gtcaatttga gaaaaaggac atatgagttt ttgcatttat
1441 taatgaaact tcctttgaaa aactgctttg aattatgatc tctgattcat tgtccatttt
1501 actaccaaat attaactaag gccttattaa tttttatata aattatatct tgtcctatta
1561 aatctagtta caatttattt catgcataag agctaatgtt attttgcaaa tgccatatat
1621 tcaaaaaagc tcaaagataa ttttctttac tattatgttc aaataatatt caatatgcat
1681 attatcttta aaaagttaaa tgttttttta atcttcaaga aatcatgcta cacttaactt
1741 ctcctagaag ctaatctata ccataatatt ttcatattca caagatatta aattaccaat
1801 tttcaaatta ttgttagtaa agaacaaaat gattctctcc caaagaaaga cacattttaa
1861 atactccttc actctaaaac tctggtatta taacttttga aagttaatat ttctacatga
1921 aatgtttagc tcttacactc tatccttcct agaaaatggt aattgagatt actcagatat
1981 taattaaata caatatcata tatatattca cagagtataa acctaaataa tgatatatta
2041 gattcaaata tttgaaataa aaacttgatt tttttgt
＜110〉Attached Tongji Hospital, Tongji Univ.
＜120〉pulmonary thromboembolism related gene and application thereof
<160>142
<210>120
<211>1885
<212>DNA
＜213〉human (Homo sapiens)
<400>120
1 ttcctaggcc accatagcgg ctggcggagg gagcgcgcgc cttgctggcc tggagggggc
61 gggggccgtg gcggctttaa agcgcccagc ccaggcgtcg cggggtgggg cggctctggc
121 ggctgcgggg cgcagggcgc agcggccaag cggggtcccc ggaagcacag ctggggtgtc
181 tccacctacg actggccgcg cgccttttct ctcccgcgcc agggaaggag cggctgcggc
241 ccccgccggg cggaggcacg gggggcgtac gaggggcgga ggggaccgcg tcgcggagga
301 gatggcgcgg cacgtgcggt gacggcaccc gagccctgag ggtcccagcc ccgcgctccg
361 cgtccccggg acagcatgga gcgcccggag cccgagctga tccggcagag ctggcgggca
421 gtgagccgca gcccgctgga gcacggcacc gtcctgtttg ccaggctgtt tgccctggag
481 cctgacctgc tgcccctctt ccagtacaac tgccgccagt tctccagccc agaggactgt
541 ctctcctcgc ctgagttcct ggaccacatc aggaaggtga tgctcgtgat tgatgctgca
601 gtgaccaatg tggaagacct gtcctcactg gaggagtacc ttgccagcct gggcaggaag
661 caccgggcag tgggtgtgaa gctcagctcc ttctcgacag tgggtgagtc tctgctctac
721 atgctggaga agtgtctggg ccctgccttc acaccagcca cacgggctgc ctggagccaa
781 ctctacgggg ccgtagtgca ggccatgagt cgaggctggg atggcgagta agaggcgacc
841 ccgcccggca gcccccatcc atctgtgtct gtctgttggc ctgtatctgt tgtagcccag
901 gctccccaag cttccctgca tcttggtcct tgtccccttg gccacactgg agaggtgatg
961 gggcagggct gggtctcagt atcctagagt ccagctgcag aaggagtggc ttttcctcca
1021 ggaaggggct tctgggtgtc ccctcatccc cagtagcctc tttcttgcgt ttctttttac
1081 cttttttggc actccctctg accccgcgat gagtgttttg gtggcagagg tgggatgagc
1141 tggaaaggta tggaggtggg agaggatggg gctcttctgt ctgtcctgct tcttcaggtg
1201 agtgcaggcc aaggcggggg tgagatggct gagcttccag cgccttctgt cctgcctgcc
1261 cagtcccttc actgctttcc tgccccaaga tggcttgctt ttcacaaata aagagaaaga
1321 gcagctttag ccttcttggt ggaatcccag gcagtgggag cagaatcaga actgccaggg
1381 aagggaaggg ggacctgggt ctcaatgggt ctcatttgag tctcgcgggc tgtgcagatg
1441 ccctgacaga gtcggtttcc tttggcggca ttccctttcc ctcattcagc acttctgctg
1501 ggaactccct gactattccg ctgctgcagg aacccagcta gctggccagg tggggagggg
1561 ctggggaccg gccaggaagg aggggtgact tcatcccaga gagacccgag ttcccccagc
1621 ccttcatcac caacccgctc ctgcaggagt gagtcttacc tcccctggcc ctcctttctg
1681 gctcagcctg cagcgactgt gaggccacag ctcctcagat tcactgcccg ctgtgtgcca
1741 gtactcaggc agctggagag aagagaaggc agcagcagag gcccccgccc tcaccccagc
1801 catctgcact tgtaccattt gctctgtgct gactgtggtc ctataaattc atgagaaata
1861 aactggttct gtgtgcaaaa aaaaa
＜110〉Attached Tongji Hospital, Tongji Univ.
＜120〉pulmonary thromboembolism related gene and application thereof
<160>142
<210>121
<211>1763
<212>DNA
＜213〉human (Homo sapiens)
<400>121
1 cttctggtaa ggaggccccg tgatcagctc cagccatttg cagtcctggc tatcccagga
61 gcttacataa agggacaatt ggagcctgag aggtgacagt gctgacacta caaggctcgg
121 agctccgggc actcagacat catgagttgg tccttgcacc cccggaattt aattctctac
181 ttctatgctc ttttatttct ctcttcaaca tgtgtagcat atgttgctac cagagacaac
241 tgctgcatct tagatgaaag attcggtagt tattgtccaa ctacctgtgg cattgcagat
301 ttcctgtcta cttatcaaac caaagtagac aaggatctac agtctttgga agacatctta
361 catcaagttg aaaacaaaac atcagaagtc aaacagctga taaaagcaat ccaactcact
421 tataatcctg atgaatcatc aaaaccaaat atgatagacg ctgctacttt gaagtccagg
481 aaaatgttag aagaaattat gaaatatgaa gcatcgattt taacacatga ctcaagtatt
541 cgatatttgc aggaaatata taattcaaat aatcaaaaga ttgttaacct gaaagagaag
601 gtagcccagc ttgaagcaca gtgccaggaa ccttgcaaag acacggtgca aatccatgat
661 atcactggga aagattgtca agacattgcc aataagggag ctaaacagag cgggctttac
721 tttattaaac ctctgaaagc taaccagcaa ttcttagtct actgtgaaat cgatgggtct
781 ggaaatggat ggactgtgtt tcagaagaga cttgatggca gtgtagattt caagaaaaac
841 tggattcaat ataaagaagg atttggacat ctgtctccta ctggcacaac agaattttgg
901 ctgggaaatg agaagattca tttgataagc acacagtctg ccatcccata tgcattaaga
961 gtggaactgg aagactggaa tggcagaacc agtactgcag actatgccat gttcaaggtg
1021 ggacctgaag ctgacaagta ccgcctaaca tatgcctact tcgctggtgg ggatgctgga
1081 gatgcctttg atggctttga ttttggcgat gatcctagtg acaagttttt cacatcccat
1141 aatggcatgc agttcagtac ctgggacaat gacaatgata agtttgaagg caactgtgct
1201 gaacaggatg gatctggttg gtggatgaac aagtgtcacg ctggccatct caatggagtt
1261 tattaccaag gtggcactta ctcaaaagca tctactccta atggttatga taatggcatt
1321 atttgggcca cttggaaaac ccggtggtat tccatgaaga aaaccactat gaagataatc
1381 ccattcaaca gactcacaat tggagaagga cagcaacacc acctgggggg agccaaacag
1441 gtcagaccag agcaccctgc ggaaacagaa tatgactcac tttaccctga ggatgatttg
1501 tagaaaatta actgctaact tctattgacc cacaaagttt cagaaattct ctgaaagttt
1561 cttccttttt tctcttacta tatttattga tttcaagtct tctattaagg acatttagcc
1621 ttcaatggaa attaaaactc atttaggact gtatttccaa attactgata tcagagttat
1681 ttaaaaattg tttatttgag gagataacat ttcaactttg ttcctaaata tataataata
1741 aaatgattga ctttatttgc aaa
＜110〉Attached Tongji Hospital, Tongji Univ.
＜120〉pulmonary thromboembolism related gene and application thereof
<160>142
<210>122
<211>4539
<212>DNA
＜213〉human (Homo sapiens)
<400>122
1 acgtcatcgc cgcgcgccgg cttgccagga gctggagggg gaggtaggcg gggcggcgcg
61 tgacctaagg cctctctgcc gcgcgcgcag gtacggggca gaagtcgcag gtacccagct
121 gctgcccaca tttctggtcc agagtcccga accccgagca ctgggatgcc tggctactcc
181 gagccaaggc actgatgttt gaactggaaa cttcaaaacg tttaataaga gtcttcagga
241 tgggtttgaa ctagacaagc tagaaatttc tttagaacac cagctctagc atgcatctcc
301 cacttttggc tttcctggag aggagcttga agaggtggtt ctgcagacag ccacagtgat
361 acttaggaaa ccagaggaat ggatttgact tttctgctag gattctctgt tatagtttct
421 ccctgagttg taagaggcat ggaaatatac atgaaactga agaacctgca aggaagggaa
481 gtggaacttt ccatgctgag tgaaaactaa ccaagtggca gttgtgactg aaaacactga
541 aacctaccac gtccagattc actggattgg gggatagagg aacggtcaca gctagggaga
601 aagaagtgat accggaaaag aaaacctaaa tgaagagaat gaggatgact gcacagtaga
661 tggccacctc tacctccaca gaggcaaagt cagcctcgtg gtggaattat ttttttcttt
721 atgatggttc caaggtaaag gaagaaggcg atccaacaag agctggcatt tgttactttt
781 atccttccca gaccctgcta gaccaacagg agttgctttg tggacagatt gctggagttg
841 tccgctgtgt ttctgacatt tctgactctc ctcctactct tgttcgtctg agaaaactga
901 agtttgccat aaaagttgat ggagattacc tttgggtgct gggctgtgct gtggagctcc
961 ctgatgtcag ctgcaagcgg tttctggatc agctagttgg attctttaat ttttacaatg
1021 gacctgtttc cctagcttat gagaactgtt ctcaggaaga actgagcacg gagtgggaca
1081 ccttcatcga gcaaattctg aaaaacacca gtgatctgca taagattttc aattccctct
1141 ggaacttgga ccaaactaaa gtggagcccc tgttgttgct gaaggcagcc cgcattctgc
1201 agacctgcca gcgctcgcct cacattctcg ctggctgcat cctctataaa ggactgattg
1261 tcagcaccca actcccgccc tccctcaccg ccaaggtcct gcttcaccga acagcacctc
1321 aggagcagag actccctacg ggagaggatg ccccgcagga acatggagcg gcattgcccc
1381 cgaatgtcca gattatccct gtttttgtga ccaaagagga agccattagt ctccacgagt
1441 tcccggtgga acagatgaca aggtctctag catctccagc aggactccag gatggttcag
1501 cccagcacca tccaaagggt gggagcacat ctgccctgaa agaaaacgcc actggccatg
1561 tggaatccat ggcctggacc accccagatc ccacatcccc tgacgaagct tgtccagatg
1621 gcaggaagga gaacggatgc ttgtctggcc atgatctgga gagcatcagg cccgcaggac
1681 tgcacaactc tgccaggggt gaggttcttg gcctcagctc ctccctgggg aaggaactag
1741 tctttctcca agaagaactc gacttgtctg aaatccacat tccagaggct caggaagtgg
1801 aaatggcctc aggtcatttt gccttcctac atgtgcctgt tccagatggc agggctcctt
1861 actgcaaggc atctctcagc gcctccagca gcctggaacc cacgcctcct gaggacacag
1921 ccatcagcag cttgcgccct ccctctgctc ctgagatgct gacccagcat ggagcccaag
1981 agcagctcga agaccatcct ggccatagca gccaagcccc cattcccaga gcagaccctc
2041 tccccagaag gacccgcagg cccttgttat tgcctcgctt agatccagga cagagaggaa
2101 acaagcttcc cacgggggaa caaggcctgg atgaggatgt tgatggggtc tgtgaaagcc
2161 acgcagcccc tggtctggaa tgcagttcag gctcagcaaa ctgtcagggt gctggcccct
2221 ctgcagatgg aatcagctcc aggctgacac cagcagagtc ctgcatgggg ctcgtgagga
2281 tgaatctcta cactcactgc gtcaaagggc tggtgctgtc cctgctggct gaggagccgc
2341 tgctgggaga cagcgcagcc atagaggaag tgtaccacag cagcctggct tcactgaatg
2401 ggctggaagt ccacctgaaa gagacgctgc ccagggatga ggcagcctcc acgagcagca
2461 cctacaactt cacacattac gaccgcattc agagcttgct gatggcaaac ctgccgcagg
2521 tggccacccc gcaggatcgc cgcttcctcc aggccgtcag cctgatgcat agcgaatttg
2581 cccagctgcc cgcgctttat gaaatgactg tcagaaatgc ctccacggct gtgtacgcct
2641 gttgcaaccc catccaggag acatatttcc agcagctggc acctgcagca cggagctccg
2701 gcttcccaaa ccctcaggat ggcgccttca gcctctccgg caaagcaaag cagaagctgc
2761 tgaagcacgg ggtgaacttg ctctgaactg cacccaggag gtgactggga aggagaaaac
2821 cagcaaagga agctctgcct tttataattg aaaaggcccc tctattttat ttttcttgaa
2881 aacattccct tttttaggaa ccaaatgata tttgagtttt tgttattcct tttgcagatt
2941 gggatgtgtt ttgggggcag gggttagttc ttcaggtcgg cagacccaga gcacttgata
3001 aagaactgta tttaatcggt agtgttgggg ccgggacggg cttggctccc tctctgccat
3061 actgagcctg aggtatttca tatctcctgc tgttccatcc cagcttgaat tggtgccaca
3121 agcttccaag ttggcatttt ttctagaacc tgatcgtcca ctagcccaga gtgtgtgtgt
3181 tcaaccccca caccaggtgg tggtaggcgg tgtgactgca cagcgaggtg ccggatctgt
3241 gagcaggccg actccactcc cacgccgcag gtaggtttct ccagtgcgct cttgctggga
3301 ggtccggatc gttcctgcag ggaagcggca gcacacggag accacttggt tgaattctgt
3361 tggaactcta ctcaaatcta ggggcgtctt ctttggaccc acaatggggg caagccttaa
3421 taatatggaa gggagtttgg gctttagaga tccctttata aaagctctgg gggctgagcc
3481 ctgagaattc agtgacaaca ggaccaacct gcgctgcctt tgactacaag tgggccgtgc
3541 agctggttcc tctcgagcga gtgtccctaa ataggagttt acaagatgtc tgggggtaaa
3601 agcactgtgc ttttcagtgg tggctgcgtg aaagggagcg acactcagct gtgtgttcct
3661 gggcttgtgt ggtacttaga acctcagttc tattacgtta tagtcagaca tttttttgac
3721 agtatgagac agactgcagg atgaaaatat ttgtcaaaat cttaactgaa tgtttactgg
3781 aagtacttga gattccattt gagagttgta ttgttaataa tttcatgtca gtgaactgat
3841 atctgatgtt tatgatatgg tgtctttttc ttgaaacaag cttccaaggg ctagaaataa
3901 aatagccaaa aaatgctgga gttctgagta attaaatggc agcatttttt tgtgacaaag
3961 gtaagggtta agacagtgtg tgtgtgtgtg tgtgtgtgtg tgtgtgtgtg tgtgcgcgcg
4021 cgcgcgcgcg cgtaacgtgg gcgcatccct cttttccttc cctgggttca gtgtggctgg
4081 gtaaggaccg tctgtttgta gggctgccag gctgcagcct gctgctccag ggagcaccag
4141 ctgcagctga tccaatacac caagcctgtg tctccctctt ctatcacctc tctccaggat
4201 ctctgctgtc tcttggatcc catctgccta gatggaagag gatcctatcc gaagctagga
4261 taaatgttgt cttactcctc tgctatgttc tcccagaaaa aattgattac aagttctctg
4321 ctgtggttgc tgcagctcca ggaagtcccc gcaatgtctc acgttgtctt tgaccagtgg
4381 tccccagtac caggccagcg aagacaactt tataatgtca tttgtgttgt gaaaattctt
4441 ccactgaccc aaaatggaac cgtacaaagc ctatccgtgt atatggaaaa gtctcatgca
4501 cctggattaa ctcagaaaaa gtaaagtcct gaaacttca
＜110〉Attached Tongji Hospital, Tongji Univ.
＜120〉pulmonary thromboembolism related gene and application thereof
<160>142
<210>123
<211>1502
<212>DNA
＜213〉human (Homo sapiens)
<400>123
1 atcacaatca gaagacagga gctgcagaac agaacacttt ctcatgtcca gggtcagatt
61 acaagagcac tcaagacttt actgacgaaa actcaggaaa tcctctatca caaagaggtt
121 tggcaactaa actaagacat taaaaggaaa ataccagatg ccactctgca ggttgcaata
181 actactactt actggataca ttcaaaccct ccagaatcaa cagttatcag gtaaccaaca
241 agaaatgcaa gccgtcgaca acctcacctc tgcgcctggt aacaccagtc tgtgcaccag
301 agactacaaa atcacccagg tcctcttccc actgctctac actgtcctgt tttttgttgg
361 acttatcaca aatggcctgg cgatgaggat tttctttcaa atccggagta aatcaaactt
421 tattattttt cttaagaaca cagtcatttc tgatcttctc atgattctga cttttccatt
481 caaaattctt agtgatgcca aactgggaac aggaccactg agaacttttg tgtgtcaagt
541 tacctccgtc atattttatt tcacaatgta tatcagtatt tcattcctgg gactgataac
601 tatcgatcgc taccagaaga ccaccaggcc atttaaaaca tccaacccca aaaatctctt
661 gggggctaag attctctctg ttgtcatctg ggcattcatg ttcttactct ctttgcctaa
721 catgattctg accaacaggc agccgagaga caagaatgtg aagaaatgct ctttccttaa
781 atcagagttc ggtctagtct ggcatgaaat agtaaattac atctgtcaag tcattttctg
841 gattaatttc ttaattgtta ttgtatgtta tacactcatt acaaaagaac tgtaccggtc
901 atacgtaaga acgaggggtg taggtaaagt ccccaggaca aaggtgaacg tcaaagtttt
961 cattatcatt gctgtattct ttatttgttt tgttcctttc cattttgccc gaattcctta
1021 caccctgagc caaacccggg atgtctttga ctgcactgct gaaaatactc tgttctatgt
1081 gaaagagagc actctgtggt taacttcctt aaatgcatgc ctggatccgt tcatctattt
1141 tttcctttgc aagtccttca gaaattcctt gataagtatg ctgaagtgcc ccaattctgc
1201 aacatctctg tcccaggaca ataggaaaaa agaacaggat ggtggtgacc caaatgaaga
1261 gactccaatg taaacaaatt aactaaggaa atatttcaat ctctttgtgt tcagaactcg
1321 ttaaagcaaa gcgctaagta aaaatattaa ctgacgaaga agcaactaag ttaataataa
1381 tgactctaaa gaaacagaag attacaaaag caattttcat ttacctttcc agtatgaaaa
1441 gctatcttaa aatatagaaa actaatctaa actgtagctg tattagcagc aaaacaaacg
1501 ac
＜110〉Attached Tongji Hospital, Tongji Univ.
＜120〉pulmonary thromboembolism related gene and application thereof
<160>142
<210>124
<211>2875
<212>DNA
＜213〉human (Homo sapiens)
<400>124
1 gaattctccg gagctgaaaa aggatcctga ctgaaagcta gaggcattga ggagcctgaa
61 gattctcagg ttttaaagac gctagagtgc caaagaagac tttgaagtgt gaaaacattt
121 cctgtaattg aaaccaaaat gtcatttata gatccttacc agcacattat agtggagcac
181 cagtattccc acaagtttac ggtagtggtg ttacgtgcca ccaaagtgac aaagggggcc
241 tttggtgaca tgcttgatac tccagatccc tatgtggaac tttttatctc tacaacccct
301 gacagcagga agagaacaag acatttcaat aatgacataa accctgtgtg gaatgagacc
361 tttgaattta ttttggatcc taatcaggaa aatgttttgg agattacgtt aatggatgcc
421 aattatgtca tggatgaaac tctagggaca gcaacattta ctgtatcttc tatgaaggtg
481 ggagaaaaga aagaagttcc ttttattttc aaccaagtca ctgaaatggt tctagaaatg
541 tctcttgaag tttgctcatg cccagaccta cgatttagta tggctctgtg tgatcaggag
601 aagactttca gacaacagag aaaagaacac ataagggaga gcatgaagaa actcttgggt
661 ccaaagaata gtgaaggatt gcattctgca cgtgatgtgc ctgtggtagc catattgggt
721 tcaggtgggg gtttccgagc catggtggga ttctctggtg tgatgaaggc attatacgaa
781 tcaggaattc tggattgtgc tacctacgtt gctggtcttt ctggctccac ctggtatatg
841 tcaaccttgt attctcaccc tgattttcca gagaaagggc cagaggagat taatgaagaa
901 ctaatgaaaa atgttagcca caatcccctt ttacttctca caccacagaa agttaaaaga
961 tatgttgagt ctttatggaa gaagaaaagc tctggacaac ctgtcacctt tactgacatc
1021 tttgggatgt taataggaga aacactaatt cataatagaa tgaatactac tctgagcagt
1081 ttgaaggaaa aagttaatac tgcacaatgc cctttacctc ttttcacctg tcttcatgtc
1141 aaacctgacg tttcagagct gatgtttgca gattgggttg aatttagtcc atacgaaatt
1201 ggcatggcta aatatggtac ttttatggct cccgacttat ttggaagcaa attttttatg
1261 ggaacagtcg ttaagaagta tgaagaaaac cccttgcatt tcttaatggg tgtctggggc
1321 agtgcctttt ccatattgtt caacagagtt ttgggcgttt ctggttcaca aagcagaggc
1381 tccacaatgg aggaagaatt agaaaatatt accacaaagc atattgtgag taatgatagc
1441 tcggacagtg atgatgaatc acacgaaccc aaaggcactg aaaatgaaga tgctggaagt
1501 gactatcaaa gtgataatca agcaagttgg attcatcgta tgataatggc cttggtgagt
1561 gattcagctt tattcaatac cagagaagga cgtgctggga aggtacacaa cttcatgctg
1621 ggcttgaatc tcaatacatc ttatccactg tctcctttga gtgactttgc cacacaggac
1681 tcctttgatg atgatgaact ggatgcagct gtagcagatc ctgatgaatt tgagcgaata
1741 tatgagcctc tggatgtcaa aagtaaaaag attcatgtag tggacagtgg gctcacattt
1801 aacctgccgt atcccttgat actgagacct cagagagggg ttgatctcat aatctccttt
1861 gacttttctg caaggccaag tgactctagt cctccgttca aggaacttct acttgcagaa
1921 aagtgggcta aaatgaacaa gctccccttt ccaaagattg atccttatgt gtttgatcgg
1981 gaagggctga aggagtgcta tgtctttaaa cccaagaatc ctgatatgga gaaagattgc
2041 ccaaccatca tccactttgt tctggccaac atcaacttca gaaagtacaa ggctccaggt
2101 gttccaaggg aaactgagga agagaaagaa atcgctgact ttgatatttt tgatgaccca
2161 gaatcaccat tttcaacctt caattttcaa tatccaaatc aagcattcaa aagactacat
2221 gatcttatgc acttcaatac tctgaacaac attgatgtga taaaagaagc catggttgaa
2281 agcattgaat atagaagaca gaatccatct cgttgctctg tttcccttag taatgttgag
2341 gcaagaagat ttttcaacaa ggagtttcta agtaaaccca aagcatagtt catgtactgg
2401 aaatggcagc agtttctgat gctgaggcag tttgcaatcc catgacaact ggatttaaaa
2461 gtacagtaca gatagtcgta ctgatcatga gagactggct gatactcaaa gttgcagtta
2521 cttagctgca tgagaataat actattataa gttaggtgac aaatgatgtt gattatgtaa
2581 ggatatactt agctacattt tcagtcagta tgaacttcct gatacaaatg tagggatata
2641 tactgtattt ttaaacattt ctcaccaact ttcttatgtg tgttcttttt aaaaattttt
2701 tttcttttaa aatatttaac agttcaatct caataagacc tcgcattatg tatgaatgtt
2761 attcactgac tagatttatt cataccatga gacaacacta tttttattta tatatgcata
2821 tatatacata catgaaataa atacatcaat ataaaaataa aaaaaaacgg aattc
＜110〉Attached Tongji Hospital, Tongji Univ.
＜120〉pulmonary thromboembolism related gene and application thereof
<160>142
<210>125
<211>1783
<212>DNA
＜213〉human (Homo sapiens)
<400>125
1 aaggaataaa gttgctgatt cattccttta cactgaaacc ctttgttgtg ccctcctctt
61 ccttcctctt tatagggaga cactctgaga aagagcacat tgtgggggcc cactccatgt
121 gatgtttgct tggttgcctg ttcccttttc tacctgcaga gcacggttcc cataagggcg
181 gcgagatcag cctcctgtct catctggaag accaccactc tggggtctca gaggaatgat
241 ggaagccttg gggtttctaa aattggaagt gaatggcccc atggtgacgg tggccctgtc
301 agtggctctc ttggccctcc tgaaatggta ctccacatca gcattctcaa gactggagaa
361 gttaggcctc agacatccca agccttctcc tttcattgga aacttgacat ttttccgcca
421 gggtttttgg gaaagccaaa tggagctcag aaagctgtat ggacctctgt gtgggtacta
481 tcttggtcgt cggatgttta ttgttatttc tgagccagac atgatcaagc aggtgttggt
541 tgagaacttc agtaacttta ccaacagaat ggcgtcgggt ttggagttca agtcggtagc
601 cgacagcgtt ctgtttttac gtgacaaaag atgggaagag gtcagaggtg ccctgatgtc
661 tgctttcagt cctgaaaagc tgaacgagat ggttcccctc atcagccaag cctgcgacct
721 tctcctggct catttaaaac gctatgcgga atctggggac gcatttgaca tccagaggtg
781 ctactgcaat tacaccacag atgtggttgc cagcgtcccg tttggcaccc cggtggactc
841 ctggcaggcc cctgaggatc cctttgtgaa acactgcaag cgtttcttcg aattctgcat
901 ccccagacct atcctggttt tactcttatc atttccatcc ataatggtcc cactggcccg
961 gattttgccc aataagaacc gagacgaact gaatggcttt tttaacaaac tcattaggaa
1021 tgtgattgcc ttgcgggacc agcaagctgc cgaagagagg cggagagact tcctccaaat
1081 ggtcctggat gcccgacatt ctgcaagtcc catgggcgtg caagactttg acatcgtcag
1141 agacgttttc tcctctactg ggtgcaagcc gaacccttcc cggcaacaccagcccagcccc
1201 tatggccagg cctttgactg tggatgagat tgtgggccag gccttcatct tcctcatcgc
1261 tggctatgaa atcatcacca acacactttc ttttgccacc tacctactgg ccaccaaccc
1321 tgactgccaa gagaagcttc tgagagaggt agacgttttt aaggagaaac acatggcccc
1381 tgagttctgc agcctcgagg aaggcctgcc ctatctggac atggtgattg cagagacgct
1441 gaggatgtac ccgccagctt tcagattcac acgggaggca gctcaggact gcgaggtgct
1501 ggggcagcgc atccccgcag gcgctgtgct agagatggcc gtgggtgccc tgcaccatga
1561 ccctgagcac tggccaagcc cggagacctt caaccctgaa aggtaccgct gcagctagaa
1621 tccaaatctg ccctaggtcc aaaaaatggt gtctatatca agatcgtatc ccgctgacac
1681 agaaggctgc cgggtggggg gagggcaccc ccaaattcaa agaaaaccct aagtgtggat
1741 gttcagaatt ttggaaaaat gtcactgaag tgattgaaag ccg
＜110〉Attached Tongji Hospital, Tongji Univ.
＜120〉pulmonary thromboembolism related gene and application thereof
<160>142
<210>126
<211>18209
<212>DNA
＜213〉human (Homo sapiens)
<400>126
1 gaagccgcat ccagacaaaa gctgccgcat ccctgccctg cccaacccct ggagggattc
61 gagtttggtg cttgtccccg tctgattctc agcgccaaac tttttgctag ttcagagatt
121 ccaagagtct gatgagttac tctgagagga aaccctctgc ctgttgttga ggaggactga
181 gcacagtgct taggcgctga gggggaaaaa gagggggaaa aaaaagaaaa tgatttcctg
241 ggaagttgtc catacagtat tcctgtttgc tcttctttat tcttccctag ctcaagatgc
301 gagcccccag tcagagatca gagctgagga aattcccgag ggggcctcca cgttggcttt
361 tgtgtttgat gtgactggtt ctatgtatga tgatttagtt caggtgattg aaggggcttc
421 caaaattttg gagacgtctt tgaaaagacc taaaagacct cttttcaact ttgcgttggt
481 gcctttccat gatccagaaa ttggcccagt gacaattacc acagatccca agaaatttca
541 atatgaactc agagaactgt atgttcaggg tggtggtgat tgcccagaaa tgagtattgg
601 agctataaaa attgccttgg aaatttctct tcctggttct ttcatctatg ttttcactga
661 tgctcggtcc aaagattacc ggctcaccca tgaggtgctg caacttatcc aacagaaaca
721 gtcacaagtc gtatttgttc tgactggaga ttgtgatgac aggacccata ttggatataa
781 agtctatgaa gaaattgcct ctacaagttc tggtcaagtg ttccatctgg acaaaaaaca
841 agttaatgag gtattaaaat gggtagaaga agcagtacag gcctccaaag ttcacctttt
901 atccacagat catttggaac aggctgtaaa tacttggaga attccttttg atcccagcct
961 gaaagaggtc actgtgtctt tgagtgggcc ttctccaatg attgaaattc gcaatccttt
1021 agggaagctg ataaaaaagg gatttggcct gcatgagcta ttaaatatcc ataactctgc
1081 caaagtagtg aatgtgaaag agccagaggc tggaatgtgg acagtgaaga cctcaagcag
1141 tggaaggcac tctgttcgca ttactggcct cagtactatt gatttccgag ctggcttttc
1201 tcgaaagccc accctggact tcaaaaaaac agtcagcaga ccagtgcaag gaatacctac
1261 ctatgtactg ctcaatactt ctggaatttc cactccagct agaatagatc ttcttgaact
1321 tttgagtatc tcaggaagtt ctcttaagac tattcctgtt aaatattacc cacatcgaaa
1381 accttatggc atatggaata tttctgactt tgtaccacca aatgaagctt tctttctcaa
1441 agtaacaggc tatgataaag atgattacct cttccagaga gtatcaagtg tttccttttc
1501 tagtattgtc ccagatgctc ccaaagttac gatgcctgag aaaaccccag gatactatct
1561 gcagccgggc caaattccct gctctgttga cagtcttttg ccctttacct tgagctttgt
1621 cagaaatgga gttacacttg gagtagacca gtatttgaaa gaatctgcca gtgtgaactt
1681 agatattgca aaggtcactt tgtctgacga aggtttctat gaatgcattg ctgtcagcag
1741 tgcaggtact ggacgggcac agacattttt tgacgtatca gagccccctc cggtcatcca
1801 agtgcctaac aatgttacag tcactcctgg agagagagca gttttaacat gtctcatcat
1861 cagtgcggtg gattacaatc taacctggca gaggaatgac agagatgtca gactggcaga
1921 gccagcgaga attaggacct tggctaatct gtcattggag ctaaagagtg tgaaattcaa
1981 cgatgctgga gagtatcatt gtatggtttc tagtgaaggt ggatcatcag ccgcttcagt
2041 tttcctcaca gtgcaagaac cacccaaagt cactgtgatg cccaagaatc agtctttcac
2101 aggagggtct gaggtctcca tcatgtgttc tgcaacaggt tatcccaaac caaagattgc
2161 ctggaccgtt aacgatatgt ttatcgtggg ttcacacagg tataggatga cctcagatgg
2221 taccttattt atcaaaaatg cagctcccaa agatgcaggg atctatggtt gcctagcaag
2281 taattcagct ggaacagata aacagaattc tactctcaga tacattgaag cccctaagtt
2341 gatggtagtt cagagtgagc tcttggttgc ccttggggat ataaccgtta tggaatgcaa
2401 aacctctggt attcctccac ctcaagttaa atggttcaaa ggagatcttg agttgaggcc
2461 ctcaacattc ctcattattg accctctctt gggacttttg aagattcaag aaacacaaga
2521 tctggatgct ggcgattata cctgtgtagc catcaatgag gctggaagag caactggcaa
2581 gataactctg gatgttggct cacctccagt tttcatacaa gaacctgctg atgtgtctat
2641 ggaaattggc tcaaatgtga cattaccttg ttatgttcag ggttatccag aaccaacaat
2701 caaatggcga agattagaca acatgccaat tttctcaaga cctttttcag ttagttccat
2761 cagccaacta agaacaggag ctctctttat tttaaactta tgggcaagtg ataaaggaac
2821 ctatatttgt gaagctgaaa accagtttgg aaagatccag tcagagacaa cagtaacagt
2881 gaccggactt gttgctccac ttattggaat cagcccttca gtggccaatg ttattgaagg
2941 acagcagctt actttgccct gtactctgtt agctggaaat cccattccag aacgtcggtg
3001 gattaagaat tcagctatgt tgctccaaaa tccttacatc actgtgcgca gtgatgggag
3061 cctccatatt gaaagagttc agcttcagga tggtggtgaa tatacttgtg tggccagtaa
3121 cgttgctggg accaataaca aaactacctc tgtggttgtg catgttctgc caaccattca
3181 gcatgggcag cagatactca gtacaattga aggcattcca gtaactttac catgcaaagc
3241 aagtggaaat cccaaaccgt ctgtcatctg gtccaagaaa ggagagctga tttcaaccag
3301 cagtgctaag ttttcagcag gagctgatgg tagtctgtat gtggtatcac ctggaggaga
3361 ggagagtggg gagtatgtct gcactgccac caatacagcc ggctacgcca aaaggaaagt
3421 gcagctaaca gtctatgtaa ggcccagagt gtttggagat caacgaggac tgtcccagga
3481 taagcctgtt gagatctccg tccttgcagg ggaagaggta acacttccat gtgaagtgaa
3541 gagcttacct ccacccataa ttacttgggc caaagaaacc cagctcatct caccgttctc
3601 tccaagacac acattcctcc cttctggttc aatgaagatc actgaaaccc gcacttcaga
3661 tagtgggatg tatctttgtg ttgccacaaa tattgctggg aatgtgactc aggctgtcaa
3721 attaaatgtc catgttcctc caaagataca gcgtggacct aaacatctca aagtccaagt
3781 tggtcaaaga gtggatattc catgtaatgc tcaagggact cctcttcctg taatcacctg
3841 gtccaaaggt ggaagcacta tgctggttga tggagagcac catgttagca atccagacgg
3901 aactttaagc atcgaccaag ccacgccctc agatgctggc atatatacat gtgttgctac
3961 taacatagca ggcactgatg aaacagagat aacgctacat gtccaagaac cacccacagt
4021 ggaagatcta gaacctccat ataacactac tttccaagaa agagtggcca atcaacgcat
4081 tgaatttcca tgtcctgcaa aaggtacccc taaaccaacc atcaaatggt tacacaatgg
4141 tagagagttg acaggcagag agcctggcat ttctatcttg gaagatggca cattgctggt
4201 tattgcttct gttacaccct atgacaatgg ggagtacatc tgtgtggcag tcaatgaagc
4261 tggaaccaca gaaagaaaat ataacctcaa agtccatgtt cctccagtaa ttaaagataa
4321 agaacaagtt acaaatgtgt cggtgttgtt aaatcagctg accaatctct tctgtgaagt
4381 ggaaggcact ccatctccca tcattatgtg gtataaagat aatgtccagg tgactgaaag
4441 cagcactatt cagactgtga acaatgggaa gatactgaag ctcttcagag ccactccaga
4501 ggatgcagga agatattcct gcaaagcaat taatattgca ggcacttctc agaagtactt
4561 taacattgat gtgctagttc cacccaccat aataggtacc aacttcccaa atgaagtctc
4621 agttgtcctc aaccgtgacg tcgcccttga atgccaggtc aaaggcactc cctttcctga
4681 tattcattgg ttcaaagatg gcaagccttt atttttgggc gatcctaatg ttgaacttct
4741 agacagagga caagtcttac atttaaagaa tgcacggaga aatgacaagg ggcgctacca
4801 atgtactgtg tctaatgcag ctggcaaaca agccaaggat ataaaactga ctatctatat
4861 tccacctagt attaaaggag gaaatgtcac cacagacata tcagtattga tcaacagcct
4921 tattaaactg gaatgtgaaa cacggggact tccaatgcct gccattactt ggtataagga
4981 cgggcagcca atcatgtcca gctcacaagc actttatatt gataaaggac aatatcttca
5041 tattcctcga gcacaggtct ctgattcagc aacatatacg tgtcacgtag ccaatgttgc
5101 tggaactgct gaaaaatcat tccatgtgga tgtctatgtt cctccaatga ttgaaggcaa
5161 cttggccacg cctttgaata agcaagtagt tattgctcat tctctgacac tggagtgcaa
5221 agctgctgga aacccttctc ccattctcac ctggttgaaa gatggtgtac ctgtgaaagc
5281 taatgacaat atccgcatag aagctggtgg gaagaaactc gaaatcatga gtgcccaaga
5341 aattgatcga ggacagtaca tatgcgtggc taccagtgtg gcaggagaaa aggaaatcaa
5401 atatgaagtt gatgtcttgg tgccaccagc tatagaagga ggagatgaaa catcttactt
5461 cattgtgatg gttaataact tactggagct agattgtcat gtgacaggct ctcccccacc
5521 aactatcatg tggctgaagg atggccagtt aattgatgaa agggatggat tcaagatttt
5581 attaaatgga cgcaaactgg ttattgctca ggctcaagtg tcaaacacag gcctttatcg
5641 gtgcatggca gcaaatactg ctggagacca caagaaggaa tttgaagtga ctgttcatgt
5701 tcctccaaca atcaagtcct caggcctttc tgagagagtt gtggtaaaat acaagcctgt
5761 cgccttgcag tgcatagcca atgggattcc aaatccttcc attacatggt taaaagatga
5821 ccagcctgtg aacactgccc aaggaaacct taaaatacag tcttctggtc gagttctaca
5881 aattgccaaa accctgttgg aagatgctgg cagatacaca tgtgtggcta ccaacgcagc
5941 tggagaaaca caacagcaca ttcaactgca tgttcatgaa ccacctagtc tggaagatgc
6001 tggaaaaatg ctgaatgaga ctgtgttggt gagcaaccct gtacagctgg agtgtaaggc
6061 agctggaaat cctgtgcctg ttattacatg gtacaaagat aatcgtctac tctcaggttc
6121 caccagcatg actttcttga acagaggaca gatcattgat attgaaagtg cccagatctc
6181 agatgctggc atatataaat gcgtggccat caactcagct ggagctacag agttatttta
6241 cagtctgcaa gttcatgtgg ccccatcaat ttctggcagc aataacatgg tggcagtggt
6301 ggttaataac ccggtgaggt tagaatgtga agccagaggt attcctgccc caagtctgac
6361 ctggttgaaa gatgggagtc ctgtttctag tttttctaat ggattacagg ttctctctgg
6421 tggtcgaatc ctagcattga ccagtgcaca aatcagcgac acaggaaggt acacctgcgt
6481 ggcagtgaat gctgctggag aaaagcaaag ggacattgac ctccgagtat atgttccgcc
6541 aaatattatg ggagaagaac agaatgtctc tgtcctcatt agccaagctg tggaattact
6601 atgtcaaagt gatgctattc ccccacctac tcttacttgg ttaaaagacg gccacccctt
6661 gctgaagaaa ccaggcctca gtatatctga aaatagaagt gtgttaaaga ttgaagatgc
6721 tcaggttcaa gacactggtc gttacacttg tgaagcaaca aatgttgctg gaaaaactga
6781 aaaaaaaaac tacaatgtca acatttgggt ccccccaaat attggtggtt ctgatgaact
6841 tactcaactt acagtcattg aagggaatct cattagtctg ttgtgtgaat caagtggtat
6901 tccaccccca aatctcatct ggaagaagaa aggctctcca gtgctgactg attccatggg
6961 gcgagttaga attttatctg ggggcaggca attacaaatt tcaattgctg aaaagtctga
7021 tgcagcactc tattcatgtg tggcgtcgaa tgttgctggg actgcaaaga aagaatacaa
7081 tctgcaagtt tacattagac caaccataac caacagtggc agccacccta ctgaaattat
7141 tgtgacccga gggaagagta tctccttgga gtgtgaggtg cagggtattc caccaccaac
7201 agtgacctgg atgaaagatg gccacccctt gatcaaggca aagggagtag aaatactgga
7261 tgaaggtcac atccttcagc tgaagaacat tcatgtatct gacacaggcc gttatgtgtg
7321 tgttgctgtg aatgtagcag gaatgactga caaaaaatat gacttaagtg tccatgctcc
7381 tccaagcatc ataggaaacc acaggtcacc tgaaaatatt agtgtggtag aaaagaactc
7441 agtatctttg acttgtgaag cttctggaat tcccctgcct tccataacct ggttcaaaga
7501 tgggtggcct gtcagcctta gcaattctgt gaggattctt tcaggaggca ggatgctacg
7561 gctgatgcag accacaatgg aagatgctgg ccaatatact tgcgttgtaa ggaatgcagc
7621 tggtgaagaa agaaaaatct ttgggctttc agtattagta ccacctcata ttgtgggtga
7681 aaatacattg gaagatgtga aggtaaaaga gaaacagagt gttacgctga cttgtgaagt
7741 gacagggaat ccagtgccag aaattacatg gcacaaagat gggcagcccc tccaagaaga
7801 tgaagcccat cacattatat ctggtggccg ttttcttcaa attaccaatg tccaggtgcc
7861 acacactgga agatatacat gtttggcttc cagtccagct ggccacaaga gcaggagctt
7921 cagtcttaat gtatttgtat ctcctacaat tgctggtgta ggtagtgatg gcaaccctga
7981 agatgtcact gtcatcctta acagccctac atctttggtc tgtgaagctt attcatatcc
8041 tccagctacc atcacctggt ttaaggatgg cactccttta gaatctaacc gaaatattcg
8101 tattcttcca ggaggcagaa ctctgcagat cctcaatgca caggaggaca atgctggaag
8161 atactcttgt gtagccacga atgaggctgg agaaatgata aagcactatg aagtgaaggt
8221 gtacattcca cccataatca ataaagggga cctttggggg ccaggtcttt cccctaaaga
8281 agtgaagatc aaagtaaaca acactctgac cttggaatgt gaagcgtatg caattccttc
8341 tgcctccctc agctggtaca aggatggaca gccccttaaa tccgatgatc atgttaatat
8401 tgctgcgaat ggacacacac ttcaaataaa ggaggctcaa atatcagaca ccggacgata
8461 tacttgtgta gcatctaaca ttgcaggtga agatgagttg gattttgatg tgaatattca
8521 agttcctcca agttttcaga aactctggga aataggaaac atgctagata ctggcaggaa
8581 tggtgaagcc aaagatgtga tcatcaacaa tcccatttct ctttactgtg agacaaatgc
8641 tgctccccct cctacactga catggtacaa agatggccac cctctgacct caagtgataa
8701 agtattgatt ttgccaggag ggcgagtgtt gcagattcct cgggctaaag tagaagatgc
8761 tgggagatac acatgtgtgg ctgtgaatga ggctggagaa gattcccttc aatatgatgt
8821 ccgtgtactc gtgccgccaa ttatcaaggg agcaaatagt gatctccctg aagaggtcac
8881 cgtgctggtg aacaagagtg cactgataga gtgtttatcc agtggcagcc cagcaccaag
8941 gaattcctgg cagaaagatg gacagccctt gctagaagat gaccatcata aatttctatc
9001 taatggacga attctgcaga ttctgaatac tcaaataaca gatatcggca ggtatgtgtg
9061 tgttgctgag aacacagctg ggagtgccaa aaaatatttt aacctcaatg ttcatgttcc
9121 tccaagtgtc attggtccta aatctgaaaa tcttaccgtc gtggtgaaca atttcatctc
9181 tttgacctgt gaggtctctg gttttccacc tcctgacctc agctggctca agaatgaaca
9241 gcccatcaaa ctgaacacaa atactctcat tgtgcctggt ggtcgaactc tacagattat
9301 tcgggccaag gtatcagatg gtggtgaata cacttgtata gctatcaatc aagctggcga
9361 aagcaagaaa aagttttccc tgactgttta tgtgccccca agcattaaag accatgacag
9421 tgaatctctt tctgtagtta atgtaagaga gggaacttct gtgtctttgg agtgtgagtc
9481 gaacgctgtg ccacctccag tcatcacttg gtataagaat gggcggatga taacagagtc
9541 tactcatgtg gagattttag ctgatggaca aatgctacac attaagaaag ctgaggtatc
9601 tgacacaggc cagtatgtat gtagagctat aaatgtagca ggacgggatg ataaaaattt
9661 ccacctcaat gtatatgtgc cacccagtat tgaaggacct gaaagagaag tgattgtgga
9721 gacgatcagc aatcctgtga cattaacatg tgatgccact gggatcccac ctcccacgat
9781 agcatggtta aagaaccaca agcgcataga aaattctgac tcactggaag ttcgtatttt
9841 gtctggaggt agcaaactcc agattgcccg gtctcagcat tcagatagtg gaaactatac
9901 atgtattgct tcaaatatgg agggaaaagc ccagaaatat tactttcttt caattcaagt
9961 tcctccaagt gttgctggtg ctgaaattcc aagtgatgtc agtgtccttc taggagaaaa
10021 tgttgagctg gtctgcaatg caaatggcat tcctactcca cttattcaat ggcttaaaga
10081 tggaaagccc atagctagtg gtgaaacaga aagaatccga gtgagtgcaa atggcagcac
10141 attaaacatt tatggagctc ttacatctga cacggggaaa tacacatgtg ttgctactaa
10201 tcccgctgga gaagaagacc gaatttttaa cttgaatgtc tatgttacac ctacaattag
10261 gggtaataaa gatgaagcag agaaactaat gactttagtg gatacttcaa taaatattga
10321 atgcagagcc acagggacgc ctccaccaca gataaactgg ctgaagaatg gacttcctct
10381 gcctctctcc tcccatatcc ggttactggc agcaggacaa gttatcagga ttgtgagagc
10441 tcaggtgtct gatgtcgctg tgtatacttg tgtggcctcc aacagagctg gggtggataa
10501 taagcattac aatcttcaag tgtttgcacc accaaatatg gacaattcaa tggggacaga
10561 ggaaatcaca gttctcaaag gtagttccac ctctatggca tgcattactg atggaacccc
10621 agctcccagt atggcctggc ttagagatgg ccagcctctg gggcttgatg cccatctgac
10681 agtcagcacc catggaatgg tcctgcagct cctcaaagca gagactgaag attcgggaaa
10741 gtacacctgc attgcctcaa atgaagctgg agaagtcagc aagcacttta tcctcaaggt
10801 cctagaacca cctcacatta atggatctga agaacatgaa gagatatcag taattgttaa
10861 taacccactt gaacttacct gcattgcttc tggaatccca gcccctaaaa tgacctggat
10921 gaaagatggc cggccccttc cacagacgga tcaagtgcaa actctaggag gaggagaggt
10981 tcttcgaatt tctactgctc aggtggagga tacaggaaga tatacatgtc tggcatccag
11041 tcctgcagga gatgatgata aggaatatct agtgagagtg catgtacctc ctaatattgc
11101 tggaactgat gagccccggg atatcactgt gttacggaac agacaagtga cattggaatg
11161 caagtcagat gcagtgcccc cacctgtaat tacttggctc agaaatggag aacggttaca
11221 ggcaacacct cgagtgcgaa tcctatctgg agggagatac ttgcaaatca acaatgctga
11281 cctaggtgat acagccaatt atacctgtgt tgccagcaac attgcaggaa agactacaag
11341 agaatttatt ctcactgtaa atgttcctcc aaacataaag gggggccccc agagccttgt
11401 aattctttta aataagtcaa ctgtattgga atgcatcgct gaaggtgtgc caactccaag
11461 gataacatgg agaaaggatg gagctgttct agctgggaat catgcaagat attccatctt
11521 ggaaaatgga ttccttcata ttcaatcagc acatgtcact gacactggac ggtatttgtg
11581 tatggccacc aatgctgctg gaacagatcg caggcgaata gatttacagg tccatgttcc
11641 tccatctatt gctccgggtc ctaccaacat gactgtaata gtaaatgttc aaactactct
11701 ggcttgtgag gctactggga taccaaaacc atcaatcaat tggagaaaaa atgggcatct
11761 tcttaatgtg gatcaaaatc agaactcata caggctcctt tcttcaggtt cactagtaat
11821 tatttcccct tctgtggatg acactgcaac ctatgaatgt actgtgacaa acggtgctgg
11881 agatgataaa agaactgtgg atctcactgt ccaagttcca ccttccatag ctgatgagcc
11941 tacagatttc ctagtaacca aacatgcccc agcagtaatt acctgcactg cttcgggagt
12001 tccatttccc tcaattcact ggaccaaaaa tggtataaga ctgcttccca ggggagatgg
12061 ctatagaatt ctgtcctcag gagcaattga aatacttgcc acccaattaa accatgctgg
12121 aagatacact tgtgtcgcta ggaatgcggc tggctctgca catcgacacg tgacccttca
12181 tgttcatgag cctccagtca ttcagcccca accaagtgaa ctacacgtca ttctgaacaa
12241 tcctatttta ttaccatgtg aagcaacagg gacacccagt cctttcatta cttggcaaaa
12301 agaaggcatc aatgttaaca cttcaggcag aaaccatgca gttcttccta gtggcggctt
12361 acagatctcc agagctgtcc gagaggatgc tggcacttac atgtgtgtgg cccagaaccc
12421 ggctggtaca gccttgggca aaatcaagtt aaatgtccaa gttcctccag tcattagccc
12481 tcatctaaag gaatatgtta ttgctgtgga caagcccatc acgttatcct gtgaagcaga
12541 tggcctccct ccgcctgaca ttacatggca taaagatggg cgtgcaattg tggaatctat
12601 ccgccagcgc gtcctcagct ctggctctct gcaaatagca tttgtccagc ctggtgatgc
12661 tggccattac acgtgcatgg cagccaatgt agcaggatca agcagcacaa gcaccaagct
12721 caccgtccat gtaccaccca ggatcagaag tacagaagga cactacacgg tcaatgagaa
12781 ttcacaagcc attcttccat gcgtagctga tggaatcccc acaccagcaa ttaactggaa
12841 aaaagacaat gttcttttag ctaacttgtt aggaaaatac actgctgaac catatggaga
12901 actcatttta gaaaatgttg tgctggagga ttctggcttc tatacctgtg ttgctaacaa
12961 tgctgcaggt gaagatacac acactgtcag cctgactgtg catgttctcc ccacttttac
13021 tgaacttcct ggagacgtgt cattaaataa aggagaacag ctacgattaa gctgtaaagc
13081 tactggtatt ccattgccca aattaacatg gaccttcaat aacaatatta ttccagccca
13141 ctttgacagt gtgaatggac acagtgaact tgttattgaa agagtgtcaa aagaggattc
13201 aggtacttat gtgtgcaccg cagagaacag cgttggcttt gtgaaggcaa ttggatttgt
13261 ttatgtgaaa gaacctccag tcttcaaagg tgattatcct tctaactgga ttgaaccact
13321 tggtgggaat gcaatcctga attgtgaggt gaaaggagac cccaccccaa ccatccagtg
13381 gaacagaaag ggagtggata ttgaaattag ccacagaatc cggcaactgg gcaatggctc
13441 cctggccatc tatggcactg ttaatgaaga tgccggtgac tatacatgtg tagctaccaa
13501 tgaagctggg gtggtggagc gcagcatgag tctgactctg caaagtcctc ctattatcac
13561 tcttgagcca gtggaaactg ttattaatgc tggtggcaaa atcatattga attgtcaggc
13621 aactggagag cctcaaccaa ccattacatg gtcccgtcaa gggcactcta tttcctggga
13681 tgaccgggtt aacgtgttgt ccaacaactc attatatatt gctgatgctc agaaagaaga
13741 tacctctgaa tttgaatgtg ttgctcgaaa cttaatgggt tctgtccttg tcagagtgcc
13801 agtcatagtc caggttcatg gtggattttc ccagtggtct gcatggagag cctgcagtgt
13861 cacctgtgga aaaggcatcc aaaagaggag tcgtctgtgc aaccagcccc ttccagccaa
13921 tggtgggaag ccctgccaag gttcagattt ggaaatgcga aactgtcaaa ataagccttg
13981 tccagtggat ggtagctggt cggaatggag tctttgggaa gaatgcacaa ggagctgtgg
14041 acgcggcaac caaaccagga ccaggacttg caataatcca tcagttcagc atggtgggcg
14101 gccatgtgaa gggaatgctg tggaaataat tatgtgcaac attaggcctt gcccagttca
14161 tggagcatgg agcgcttggc agccttgggg aacatgcagc gaaagttgtg ggaaaggtac
14221 tcagacaaga gcaagacttt gtaataaccc accaccagcg tttggtgggt cctactgtga
14281 tggagcagaa acacagatgc aagtttgcaa tgaaagaaat tgtccaattc atggcaagtg
14341 ggcgacttgg gccagttgga gtgcctgttc tgtgtcatgt ggaggaggtg ccagacagag
14401 aacaaggggc tgctccgacc ctgtgcccca gtatggagga aggaaatgcg aagggagtga
14461 tgtccagagt gatttttgca acagtgaccc ttgcccaacc catggtaact ggagtccttg
14521 gagtggctgg ggaacatgca gccggacgtg taacggaggg cagatgcggc ggtaccgcac
14581 atgtgataac cctcctccct ccaatggggg aagagcttgt gggggaccag actcccagat
14641 ccagaggtgc aacactgaca tgtgtcctgt ggatggaagt tggggaagct ggcatagttg
14701 gagccagtgc tctgcctcct gtggaggagg tgaaaagact cggaagcggc tgtgcgacca
14761 tcctgtgcca gttaaaggtg gccgtccctg tcccggagac actactcagg tgaccaggtg
14821 caatgtacaa gcatgtccag gtgggcccca gcgagccaga ggaagtgtta ttggaaatat
14881 taatgatgtt gaatttggaa ttgctttcct taatgccaca ataactgata gccctaactc
14941 tgatactaga ataatacgtg ccaaaattac caatgtacct cgtagtcttg gttcagcaat
15001 gagaaagata gtttctattc taaatcccat ttattggaca acagcaaagg aaataggaga
15061 agcagtcaat ggctttaccc tcaccaatgc agtcttcaaa agagaaactc aagtggaatt
15121 tgcaactgga gaaatcttgc agatgagtca tattgcccgg ggcttggatt ccgatggttc
15181 tttgctgcta gatatcgttg tgagtggcta tgtcctacag cttcagtcac ctgctgaagt
15241 cactgtaaag gattacacag aggactacat tcaaacaggt cctgggcagc tgtacgccta
15301 ctcaacccgg ctgttcacca ttgatggcat cagcatccca tacacatgga accacaccgt
15361 tttctatgat caggcacagg gaagaatgcc tttcttggtt gaaacacttc atgcatcctc
15421 tgtggaatct gactataacc agatagaaga gacactgggt tttaaaattc atgcttcaat
15481 atccaaagga gatcgcagta atcagtgccc ctccgggttt accttagact cagttggacc
15541 tttttgtgct gatgaggatg aatgtgcagc agggaatccc tgctcccata gctgccacaa
15601 tgccatgggg acttactact gctcctgccc taaaggcctc accatagctg cagatggaag
15661 aacttgtcaa gatattgatg agtgtgcttt gggtaggcat acctgccacg ctggtcagga
15721 ctgtgacaat acgattggat cttatcgctg tgtggtccgt tgtggaagtg gctttcgaag
15781 aacctctgat gggctgagtt gtcaagatat taatgaatgt caagaatcca gcccctgtca
15841 ccagcgctgt ttcaatgcca taggaagttt ccattgtgga tgtgaacctg ggtatcagct
15901 caaaggcaga aaatgcatgg atgtgaacga gtgtagacaa aatgtatgca gaccagatca
15961 gcactgtaag aacacccgtg gtggctataa gtgcattgat ctttgtccaa atggaatgac
16021 caaggcagaa aatggaacct gtattgatat tgatgaatgt aaagatggga cccatcagtg
16081 cagatataac cagatatgtg agaatacaag aggcagctat cgttgtgtat gcccaagagg
16141 ttatcggtct caaggagttg gaagaccctg catggacatt aatgaatgtg aacaagtgcc
16201 taaaccttgt gcacatcagt gctccaacac ccccggcagc ttcaagtgta tctgtccacc
16261 aggacaacat ttattagggg acgggaaatc ttgcgctgga ttggagaggc tgccaaatta
16321 tggcactcaa tacagtagct ataaccttgc acggttctcc cctgtgagaa acaactatca
16381 acctcaacag cattacagac agtactcaca tctctacagc tcctactcag agtatagaaa
16441 cagcagaaca tctctctcca ggactagaag gactattagg aaaacttgcc ctgaaggctc
16501 tgaggcaagc catgacacat gtgtagatat tgatgaatgt gaaaatacag atgcctgcca
16561 gcatgagtgt aagaatacct ttggaagtta tcagtgcatc tgcccacgtg gctatcaact
16621 cacacacaat ggaaagacat gccaagatat cgatgaatgt ctggagcaga atgtgcactg
16681 tggacccaat cgcatgtgct tcaacatgag aggaagctac cagtgcatcg atacaccctg
16741 tccacccaac taccaacggg atcctgtttc agggttctgc ctcaagaact gtccacccaa
16801 tgatttggaa tgtgccttga gcccatatgc cttggaatac aaactcgtct ccctcccatt
16861 tggaatagcc accaatcaag atttaatccg gctggttgca tacacagagg atggagtgat
16921 gcatcccagg acaactttcc tcatggtaga tgaggaacag actgttcctt ttgccttgag
16981 ggatgaaaac ctgaaaggag tggtgtatac aacacgacca ctacgagaag cagagaccta
17041 ccgcatgagg gtccgagcct catcctacag tgccaatggg accattgaat atcagaccac
17101 attcatagtt tatatagctg tgtccgccta tccatactaa ggaactctcc aaagcctatt
17161 ccacatattt aaaccgcatt aatcatggca atcaagcccc cttccagatt actgtctctt
17221 gaacagttgc aatcttggca gcttgaaaat ggtgctacac tctgttttgt gtgccttcct
17281 tggtacttct gaggtatttt catgatccca ccatggtcat atcttgaagt atggtctaga
17341 aaagtccctt attattttat ttattacact ggagcagtta cttcccaaag attattctga
17401 acatctaaca ggacatatca gtgatggttt acagtagtgt agtacctaag atcattttcc
17461 tgaaagccaa accaaacaac gaaaaacaag aacaactaat tcagaatcaa atagagtttt
17521 tgagcatttg actattttta gaatcataaa attagttact aagtattttg atcaaagctt
17581 ataaaataac ttacggagat ttttgtaagt attgatacat tataatagga cttgcctatt
17641 ttcattttta agaagaaaaa caccactcat tttataaaat atagtacagc tactataagg
17701 cttgtttgat cccaaatggt gcttatcttg attgaacatt cagaacaagg atattatttt
17761 cagtgatttt gtgagatcag ctgaaccact tatgataata ataataaaaa agactacttt
17821 gccctcacgt cagttgtaca tggcatggaa ctttaaaaat tttaatataa actttcatcc
17881 agttagcttc ataactttta cgttccagaa ttttgtttat tttcctgtca atgaaagcaa
17941 tttttaaaga taccagtggg acaggtttgg ttttttaaaa atctcatgtg ttcaaattaa
18001 cataaatatt acacgtcaat acactgtaca tggtggtaat agactctaag caattgccaa
18061 gatgtattct atttttatga agtgtatata tattacctta gtgtgcattt tctatataat
18121 atcttgatgg actcttttat aaaattattt tataaaaaac aatgttacac taaaatcagc
18181 ctaaataaat tttcacaact ttttttcat
＜110〉Attached Tongji Hospital, Tongji Univ.
＜120〉pulmonary thromboembolism related gene and application thereof
<160>142
<210>127
<211>3033
<212>DNA
＜213〉human (Homo sapiens)
<400>127
1 gagtgtgtga cccagccctt cccccgtggc caagcagaga gagtggcctt gaggaagcca
61 tagcagcagg agcagcatgg cctctgctgc ctctgtgacc agcctggcag atgaagtcaa
121 ctgccccatc tgtcagggta ccctgaggga gccggtcact atcgactgcg gccacaactt
181 ctgccgggcc tgccttaccc gctactgtga gataccaggc ccagacctgg aggagtcccc
241 tacttgccca ctctgcaaag aacccttccg tcctgggagc ttccggccca actggcagct
301 ggctaacgtg gtggagaaca ttgagcgcct ccagctggtg tccacactgg gtttgggaga
361 ggaggatgtc tgccaagagc acggagggaa gatctacttc ttctgtgagg atgatgagat
421 gcagttgtgc gtggtgtgcc gggaggctgg ggagcacgct acccacacca tgcgcttcct
481 ggaggatgca gcggctccct atagggaaca aatccataag tgtcttaaat gtctaagaaa
541 agagagagag gagattcaag aaatccagtc aagaaaaaat aaaaggatgc aagtcctcct
601 gactcaggtg tccaccaaga gacaacaggt gatttctgag ttcgcacacc tgaggaagtt
661 tctagaggaa cagcagagca tcctcttagc acaattggag agccaggatg gggacatctt
721 gaggcaacgg gatgaatttg atttgctggt tgctggggag atctgccggt ttagtgctct
781 tattgaagaa ctggaggaga agaatgagag gccagcaagg gagctcctga cggacatcag
841 aagcactcta ataagatgtg aaaccagaaa gtgccggaaa ccggtggctg tgtcgccaga
901 gctgggccag aggattcggg actttcccca gcaggccctc ccgctgcaga gggagatgaa
961 gatgtttctg gaaaaactat gctttgagtt ggactatgag ccagctcaca tttctctaga
1021 ccctcagact tcccacccca agctcctctt gtccgaggac caccagcgag ctcagttctc
1081 ctacaaatgg cagaactcac cagacaaccc ccagcgtttt gaccgggcca cctgtgttct
1141 ggcccacact ggcatcacag gggggagaca cacgtgggtg tggatggcca gggtacctgg
1201 ggactcaggc ggctgccagt tctgctcacc accatccgtg cttggcacag aagtagctgc
1261 atagaaagag cactggattt gaagtcagaa gacctgggtt cttgaaccag cctgtcaacc
1321 agttgtatga ctttaaacaa ggcatctcac ctcttttca tcttgttttct tccaataatg
1381 ttagagttca tgtaatcaca ttctctagaa ccatttagtt tgtgttaact atgaaccaag
1441 cagtgtggtg gccactggtg acttgaaaat atagagaaaa aaaaaacctg ctctatatct
1501 gaaagagctc ttgggaagac agagaaacat aaagaggaaa ttacagcaca gtgtggtggg
1561 tgttacggga agtccaaccc cagcattatg ggagttcagg ggaaggggca tagcccagcc
1621 tggaaggaga gggtgagtgg gggatggctt tctgaaaagg gtggtctaaa ggatgcctat
1681 ggtcaatagg gaaaagaggg gaagaagcat cttaagaaga ggaaacagca gagaactggc
1741 tggatgacct gtgactctgg agcactgggt tgtctccatt gtcattatgg gcagatgtgt
1801 gccatcccca gccgacgcca ctcactgcct ccttcctcct ggtgttgcca cttctgggtg
1861 agattaaggt gcagggcctg ggggcaggag gacataaggt atagccataa atcataaccc
1921 agggaccaca ctcaacccta gggaaattgt cttcctgatc agttgattac catctgaggt
1981 caagaaatga gatagtggga gcaaatgggt cacaaatagc tcagctgtgg gctcagaaac
2041 tgctaggtaa aagaattcca gaaggaggcc agggcataag ttggatgacc tatgaacttt
2101 agtctaaaga attgagacta ccgtaattga gactactgta gtgacatctg agaaatggga
2161 tggaagagtg accatgtttt attttcttgt tcttgtcact attgtatttt attttgcata
2221 atcatgccct tcactgacag tctccttaac atcatctgtt tactctgctc agtgtaaact
2281 acaatgctct gtcatctccc tactgggtct cctgggagga ggggagccat ccagggtgca
2341 aactcaaagg cagagggcac agcgtgctta ggcccaagct tagaattcaa ttgagaagtt
2401 ctgttgttca tccttacctc agcaggtaga aaagaggtgg agatcagaag ccagggatta
2461 gagattgaat tgctttccct gggagtgtgc agtatctcat taaaatgttg tatattcaaa
2521 aaaatacaga cacacacaag tgcctatata atgataaaac atatccaaag cacccaaacc
2581 tgtgattcca gaaaagtaga tcctattttt gtttattttt attggcttta gctgtgtctt
2641 ttgaaaggac tattatcctc taaaatgtat gtgtatgaag atcctggctt gcagctcggg
2701 agctttacac accttgtgtc actttatctt ggtaacgagc caagatcatg caaccagttc
2761 atccatgtct gacccaagag ctcttaactg ctatgctgca ctgcctcatt cagagataga
2821 tgcctgcatg ggtcctggcg attattttaa tgctggctac acccccacag gtgacttgga
2881 ttcagaaata caatttatat ttcttctttt taaattgttt tattttattt ttcttttaat
2941 agttatatgt cagtgagaac aatttatatg tcttacactg agaaataaaa ctgctcataa
3001 gtgaaaaaaa aaaaaaaaaa aaaaaaaaaa aaa
＜110〉Attached Tongji Hospital, Tongji Univ.
＜120〉pulmonary thromboembolism related gene and application thereof
<160>142
<210>128
<211>3346
<212>DNA
＜213〉human (Homo sapiens)
<400>128
1 aaccacgatg tctttggcac agcctctcat ctgtcagatg ggagcgggga ccccggagag
61 ggagtcagcc gaggtcctgg cattccttgt gaacccccgt ctgtgggttt ctggtccagt
121 gtcccttctc cagattagat ggcttaggcc tcctctaagg gggtgggcgt gcacatccgg
181 agagctgtct ggtgtgcagg actgggctgc aggttaccct gaactgcaac catcttagag
241 caaggcccag cttgcagcag gaggagctgc aggccgccca ccctagccac ggcccctgcc
301 ctggcaggaa gcttccaaga gtaaacactg cctaatcgtc ccgcccagta gtgagcaggc
361 ctgtcccatt ccatactgac cagattccca gtcaccaagg ccccctctca ctccgctcca
421 ctcctcgggc tggctctcct gaggatgcac cagcgtcacc cccgggcaag atgccctccc
481 ctctgtgtgg ccggaatcct tgcctgtggc tttctcctgg gctgctgggg accctcccat
541 ttccagcaga gttgtcttca ggctttggag ccacaggccg tgtcttctta cttgagccct
601 ggtgctccct taaaaggccg ccctccttcc cctggcttcc agaggcagag gcagaggcag
661 aggcgggctg caggcggcat cctacacctg gagctgctgg tggccgtggg ccccgatgtc
721 ttccaggctc accaggagga cacagagcgc tatgtgctca ccaacctcaa catcggggca
781 gaactgcttc gggacccgtc cctgggggct cagtttcggg tgcacctggt gaagatggtc
841 attctgacag agcctgaggg tgccccaaat atcacagcca acctcacctc gtccctgctg
901 agcgtctgtg ggtggagcca gaccatcaac cctgaggacg acacggatcc tggccatgct
961 gacctggtcc tctatatcac taggtttgac ctggagttgc ctgatggtaa ccggcaggtg
1021 cggggcgtca cccagctggg cggtgcctgc tccccaacct ggagctgcct cattaccgag
1081 gacactggct tcgacctggg agtcaccatt gcccatgaga ttgggcacag cttcggcctg
1141 gagcacgacg gcgcgcccgg cagcggctgc ggccccagcg gacacgtgat ggcttcggac
1201 ggcgccgcgc cccgcgccgg cctcgcctgg tccccctgca gccgccggca gctgctgagc
1261 ctgctcagac ccgtccctcc gtcgccgctc cctctgctgg ccacccacct ctgcgccggc
1321 aggagcctta gtcttggtcc cagccaagag ccggctcctg gtggggggcg cgggccgaga
1381 actcctgttc ccactcacaa aaggccacgc ttccaaacgc ttccatcctc gtgcccactc
1441 ctccgtcccg cctcctcccg gtgtacaccc cgggactgag ccgggcctga gccgggcctt
1501 gtcgcagcgc aggacgggcg cgctgcgtgt gggacccgcc gcggcctcaa cccgggtccg
1561 cggggcaccc gccggatgcg cagcctggcc tctactacag cgccaacgag cagtgccgcg
1621 tggccttcgg ccccaaggct gtcgcctgca ccttcgccag ggagcacctg gtgagtctgc
1681 cggcggtggc ctgggattgg ctgtgaggtc cctccgcatc acccagctca cgtcccccaa
1741 aacgtgcatg gatatgtgcc aggccctctc ctgccacaca gacccgctgg accaaagcag
1801 ctgcagccgc ctcctcgttc ctctcctgga tgggacagaa tgtggcgtgg agaagtggtg
1861 ctccaagggt cgctgccgct ccctggtgga gctgaccccc atagcagcag tgcatgggcg
1921 ctggtctagc tggggtcccc gaagtccttg ctcccgctcc tgcggaggag gtgtggtcac
1981 caggaggcgg cagtgcaaca accccagacc tgcctttggg gggcgtgcat gtgttggtgc
2041 tgacctccag gccgagatgt gcaacactca ggcctgcgag aagacccagc tggagttcat
2101 gtcgcaacag tgcgccagga ccgacggcca gccgctgcgc tcctcccctg gcggcgcctc
2161 cttctaccac tggggtgctg ctgtaccaca cagccaaggg gatgctctgt gcagacacat
2221 gtgccgggcc attggcgaga gcttcatcat gaagcgtgga gacagcttcc tcgatgggac
2281 ccggtgtatg ccaagtggcc cccgggagga cgggaccctg agcctgtgtg tgtcgggcag
2341 ctgcaggaca tttggctgtg atggtaggat ggactcccag caggtatgggacaggtgcca
2401 ggtgtgtggt ggggacaaca gcacgtgcag cccacggaag ggctctttca cagctggcag
2461 agcgagagaa tatgtcacat ttctgacagt tacccccaac ctgaccagtg tctacattgc
2521 caaccacagg cctctcttca cacacttggc ggtgaggatc ggagggcgct atgtcgtggc
2581 tgggaagatg agcatctccc ctaacaccac ctacccctcc ctcctggagg atggtcgtgt
2641 cgagtacaga gtggccctca ccgaggaccg gctgccccgc ctggaggaga tccgcatctg
2701 gggacccctc caggaagatg ctgacatcca ggtgggaggt gtcagagccc agctcatgca
2761 catcagctgg tggagcaggc ctggccttgg agaacgagac ctgtgtgcca ggggcagatg
2821 gcctggaggc tccagtgact gaggggcctg gctccgtaga tgagaagctg cctgcccctg
2881 agccctgtgt cgggatgtca tgtcctccag gctggggcca tctggatgcc acctctgcag
2941 gggagaaggc tccctcccca tggggcagca tcaggacggg ggctcaagct gcacacgtgt
3001 ggagccctgc ggcagggtcg tgctccgtct cctgcgggcg aggtctgatg gagctgcgtt
3061 tcctgtgcat ggactctgcc ctcagggtgc ctgtccagga agagctgtgt ggcctggcaa
3121 gcaagcctgg gagccggcgg gaggtctgcc aggctgtccc gtgccctgct cggtggcagt
3181 acaagctggc ggcctgcagc gtgagctgtg ggagaggggt cgtgcggagg atcctgtatt
3241 gtgcccgggc ccatggggag gacgatggtg aggagatcct gttggagacc cagtgccagg
3301 ggctgcctcg cccggaaccc caggaggcct gcagcctgga gccctg
＜110〉Attached Tongji Hospital, Tongji Univ.
＜120〉pulmonary thromboembolism related gene and application thereof
<160>142
<210>129
<211>5115
<212>DNA
＜213〉human (Homo sapiens)
<400>129
1 ccagccatgg gctcggggcg cgtacccggg ctctgcctgc ttgtcctgct ggtccacgcc
61 cgcgccgccc agtacagcaa agccgcgcaa gatgtggatg agtgtgtgga ggggactgac
121 aactgccaca tcgatgctat ctgccagaac agcccgaggt catacaagtg catctgcaag
181 tctggctaca caggggacgg caaacactgc aaagacgtgg atgagtgcga gcgagaggat
241 aatgcaggtt gtgtgcatga ctgtgtcaac atccctggca attaccggtg tacctgctat
301 gatggattcc acctggcaca tgacggacac aactgtctgg atgtggacga gtgtgccgag
361 ggcaacggcg gctgtcagca gagctgtgtc aacatgatgg gcagctatga gtgccactgc
421 cgggaaggct tcttcctcag cgacaaccag catacctgta tccagcggcc agaagaagga
481 atgaattgca tgaacaagaa ccacggctgt gcccacattt gccgggagac acccaagggg
541 ggtattgcct gtgaatgccg tcctggcttt gagcttacca agaaccaacg ggactgtaaa
601 ttgacatgca actatggtaa cggcggctgc cagcacacgt gtgatgagac agagcagggt
661 ccccggtgcg gctgccatat caagtttgtg ctccataccg acgggaagac atgcatcgag
721 acctgtgctg tcaacaacgg gggctgtgac agtaagtgcc atgatgcagc gactggtgtc
781 cactgcacct gccctgtggg cttcatgctg cagccagaca ggaagacgtg caaagatata
841 gatgagtgcc gcttaaacaa cgggggctgt gaggatattt gccgcaacac agtgggcagc
901 ttcgaatgca gttgcaagaa aggctataag cttctcatca atgagaggaa ctgccaggat
961 atagacgagt gttcctttga tcgaacctgt gaccacatat gtgtcaacac accgggaagc
1021 ttccagtgtc tctgccatcg tggctacctg ttgtatggta tcacccattg tggggatgtg
1081 gatgaatgca gcatcaaccg gggaggttgc cgctttggct gcatcaagac tcctggcagc
1141 taccagtgta cctgcccagc aggccagggt cggctgcact ggaatggcaa agattgcaca
1201 gagccactga agtgtcaggg cagtcctggg gcctcgaaag ccatgctcag ctgcaaccgg
1261 tctggcaaga aggacacctg tgccctgacc tgtccctcca gggcccgatt tttgccagag
1321 tctgagaatg gcttcacggt gagctgtggg acccccagcc ccagggctgc tccagcccga
1381 gctggccaca atgggaacag caccaactcc aaccactgcc atgaggctgc agtgctgtcc
1441 attaaacaac gggcctcctt caagatcaag gatgccaaat gccgtttgca cctgcgaaac
1501 aaaggcaaaa cagaggaggc tggcagaatc acagggccag gtggtgcccc ctgctctgaa
1561 tgccaggtca ccttcatcca ccttaagtgt gactcctctc ggaagggcaa gggccgacgg
1621 gcccggaccc ctccaggcaa agaggtcaca aggctcaccc tggaactgga ggcagaggtc
1681 agagccgaag aaaccacagc cagctgtggg ctgccctgcc tccgacagcg aatggaacgg
1741 cggctgaaag gatccctgaa gatgctcaga aagtccatca accaggaccg cttcctgctg
1801 cgcctggcag gccttgatta tgagctggcc cacaagccgg gcctggtagc cggggagcga
1861 gcagagccga tggagtcctg taggcccggg cagcaccgtg ctgggaccaa gtgtgtcagc
1921 tgcccgcagg gaacgtatta ccacggccag acggagcagt gtgtgccatg cccagcgggc
1981 accttccagg agagagaagg gcagctctcc tgcgaccttt gccctgggag tgatgcccac
2041 gggcctcttg gagccaccaa cgtcaccacg tgtgcaggtc agtgcccacc tggccaacac
2101 tctgtagatg ggttcaagcc ctgtcagcca tgcccacgtg gcacctacca acctgaagca
2161 ggacggaccc tatgcttccc ttgtggtggg ggcctcacca ccaagcatga aggggccatt
2221 tccttccaag actgtgacac caaagtccag tgctccccag ggcactacta caacaccagc
2281 atccaccgct gtattcgctg tgccatgggc tcctatcagc ccgacttccg tcagaacttc
2341 tgcagccgct gtccaggaaa cacaagcaca gactttgatg gctctaccag tgtggcccaa
2401 tgcaagaatc gtcagtgtgg tggggagctg ggtgagttca ctggctatat tgagtccccc
2461 aactacccgg gcaactaccc agctggtgtg gagtgcatct ggaacatcaa ccccccaccc
2521 aagcgcaaga tccttatcgt ggtaccagag atcttcctgc catctgagga tgagtgtggg
2581 gacgtcctgg tcatgagaaa gaactcatcc ccatcctcca ttaccactta tgagacctgc
2641 cagacctacg agcgtcccat tgccttcact gcccgttcca ggaagctctg gatcaacttc
2701 aagacaagcg aggccaacag cgcccgtggc ttccagattc cctatgttac ctatgatgag
2761 gactatgagc agctggtaga agacattgtg cgagatggcc ggctctatgc ctctgaaaac
2821 caccaggaga ttttaaagga caagaagctc atcaaggcct tctttgaggt gctagcccac
2881 ccccagaact acttcaagta cacagagaaa cacaaggaga tgctgccaaa atccttcatc
2941 aagctgctcc gctccaaagt ttccagcttc ctgaggccct acaaatagta accctaggct
3001 cagagaccca attttttaag cccccagact ccttagccct cagagccggc agccccctac
3061 cctcagacaa ggaactctct cctctctttt tggagggaaa aaaaaaatat cactacacaa
3121 accaggcact ctccctttct gtctttctag tttcctttcc ttgtctctct ctgcctgcct
3181 ctctactgtt cccccttttc taacacacta cctagaaaag ccattcagta ctggctctag
3241 tccccgtgag atgtaaagaa acagtacagc cccttccact gcccatttta ccagctcaca
3301 ttcccgaccc catcagcttg gaagggtgct agaggcccat caaggaagtg ggtctggtgg
3361 gaaacgggga ggggaaagaa gggcttctgc cattataggg ttgtgccttg ctagtcaggg
3421 gccaaaatgt cccctggctc tgctccctag ggtgattcta acagcccagg gtcctgccaa
3481 agaagccttt gatttacagg cttaatgcca gcaccagtcc tctggggcac atggtttgag
3541 ctctggactt cccacatggc cagctttctt gtctatacag atcctctctt tctttcccta
3601 cgtctgcctg gggtctactc cataagggtt tacaaatggc ccacaacact gagttagtgg
3661 acaccggcta aatgaggaag agcagcaggc attgtcatgg tgaatgcccc gctgtagctc
3721 cctgagagaa agactgtaac tctgcaggac agaaacaagg ttttaaagca ttgccaaaaa
3781 aaagaaaaca gaaagaaaaa atgtatcatc taaaggacta gacacagaac aattggaagt
3841 caacttcaaa cactaatccc ttttcttgtc ttccctggcc cagccacctc ctcagcccca
3901 tgtgatgctc cctgggggag ccctactccc cttgctacat gttgtcctta aacatggtta
3961 ttgacctgaa gccagcctag gccttgccct acagttgttt ttcccttgta gccccagctg
4021 gcttgtgggc ttcaccaaag aggaccccac tctgaagcca gcctggagcc acctacctct
4081 ggcctcaggc tgtgggcagc aaaaggaatg tgtgtgcact tggcgagcct cctgcccacc
4141 ctgtccacac ctaataagtg caatcatttt gagtctttct atgttgtcta gacggagggg
4201 tttttgtttt ctgggtttgt tttttgtttt tgtttcttct tcctctatta gcaaaaccct
4261 atttatagct gcccaagaga aaagagtgta tgtttggagt ggaagaaaat cggttttgaa
4321 tctcatgaac cttgagtgct ggagcatctg atctgtctct atgccaccac tggccaccta
4381 gagcccttgg ctgtggtaat ccagggtaat tgcgcagagg catctgatgt gtaggaaagt
4441 aattctgggg atttgatgga gcagaaagga gagagaccta tgtttgctaa accaatcttg
4501 ctatccctat gcctctccat ggagtcagtg tggacctcat gattatagag gccaatggaa
4561 ctggtcagtg attctctacc ccaagtaggg aaaacctcca tcttttccct gtcttcatcc
4621 tgttatcccc tggtgtacac atggaagagg accaggacat accacctggg gatgggctga
4681 ctcagggtcc cgaggccaga gacaaagctg tgggagccaa gaataagaca gaaggcatca
4741 gatatttgcc tggctctggt cacttccctt tgaagttgac ttcaagctta gcttcctcaa
4801 ctactgtttt tcagaaggaa gaaagaatca aatggaagaa gaatcaagtc catgcccaag
4861 cccaaagcct gcacacattc tgcccttaat ccaagtgttg cctataaaat tattttctgt
4921 tttctcactc tagttccccc aaagctgtag tcccaatcaa tcaaaggcta ccaactgagt
4981 cctcaggttc atttcttttt tttttttttt tctttttaac tctcctggta actcacagaa
5041 cagctcaggt tcatttctag gtgactgtcc taggctactg ctcccccagg agactcaaca
5101 ctaaataaag gagtc
＜110〉Attached Tongji Hospital, Tongji Univ.
＜120〉pulmonary thromboembolism related gene and application thereof
<160>142
<210>130
<211>2436
<212>DNA
＜213〉human (Homo sapiens)
<400>130
1 atccccgtgt gggggagggg ggccttcggt ctctccccag cctcttcctt ccccctggcc
61 tgagggtggg tggggagggg cagttcctct ttccttccca agcaccgagg aggccccagc
121 tccctagggg ctgagaagct ggagtcctgg gcaaggggag gagctgagcc ctactcttgc
181 aagacccccg gcctcctcac cccacgcggg aagcatgaac agaaaagaca gtaagaggaa
241 gtcccaccag gaatgcaccg gaaaaatagg agggcgaggc cggccccgcc aagtgcgccg
301 ccacaagaca tgccccagcc ctcgggaaat cagcaaggtc atggcttcca tgaacctggg
361 cctgctgagt gagggcggct gcagcgaaga tgagctgctg gagaaatgca tccagtcctt
421 cgattcagct ggcagcctgt gccacgagga ccacatgctc aacatggtgc tggccatgca
481 cagctgggtg ctgccgtccg ccgacctggc tgcccgcctg ctgacctcat accagaaggc
541 cacaggggac acccaggagc tgagacggct gcagatctgt cacctggtca ggtactggct
601 gatgcgacac cctgaggtga tgcaccagga tccccagcta gaagaagtca taggtcgttt
661 ctgggccacc gtggcccggg agggcaactc agcccagaga agactgggag actcttctga
721 cctcctgagc cctggtggcc ctggcccccc actcccaatg agcagcccag gcctgggcaa
781 aaagcgcaaa gtgtccttgc ttttcgacca cttggagacg ggggagctgg ctcagcacct
841 cacctacctg gagttccggt ccttccaggc tatcacgccc caggacctgc ggagctacgt
901 tttgcagggc tcagtacgag gctgcccggc cctggagggc tccgtaggtc tcagcaacag
961 cgtgtcccgc tgggtgcagg tgatggtgct gagccgtccc gggcccctac agcgtgcaca
1021 ggtgctggac aagttcattc acgtggcaca gaggctccac cagctgcaga atttcaacac
1081 gctgatggca gtcacagggg gcctgtgtca cagtgccatc tccagactca aggactccca
1141 tgcccacctg agccctgaca gcaccaaggc cctcctggag ctcactgagc tccttgcctc
1201 ccacaacaac tacgcccgct accgccgcac ctgggctggc tgcgcgggtt tccggctgcc
1261 tgtactgggc gtgcacctca aggacctggt gtccctgcat gaggcacagc ccgacaggtt
1321 gcctgacggc cgcctgcacc tacccaagct gaacaacctc tacctgcggc tgcaggagct
1381 ggtggccctc caagggcagc atccaccctg cagcgccaat gaggatctgc tgcacctgct
1441 cacgctctcc ctggacctct tctacacgga agacgagatc tatgagcttt cttatgcccg
1501 ggagccgcgt tgtcccaaga gcctgccacc ctcccccttc aatgcacctc tggtggtgga
1561 gtgggcccct ggtgtgacac ccaagccgga cagggtcaca ctgggtcggc atgtggagca
1621 gctggtggag tctgtgttca agaattatga ccctgaaggc cgaggaacaa tctctcagga
1681 ggactttgag cgactctcgg gcaattttcc cttcgcctgc catgggcttc acccaccccc
1741 acgccagggg agaggatcct tcagcagaga ggagctgaca gggtacctgc tccgggccag
1801 cgccatctgc tccaagttgg gcctggcctt cctgcacacc ttccatgagg tcaccttccg
1861 aaagcctacc ttctgcgaca gctgcagtgg cttcctctgg ggtgtcacca agcaaggcta
1921 ccgctgtcgg gagtgcgggc tgtgttgcca caaacactgc agagaccagg tgaaggtaga
1981 atgtaagaag aggccagggg ccaagggcga tgcaggaccc cccggagctc ctgtcccatc
2041 cacaccagct ccccatgcca gctgtggctc cgaggaaaat cactcctaca cgctatccct
2101 ggagcctgag actgggtgcc agcttcgcca tgcctggacc cagactgaat ccccacaccc
2161 ttcctgggaa acagatacgg tcccctgccc ggtgatggac ccaccatcaa ctgcatcctc
2221 caagctggat tcctagacat ctcttggtct cctctcttcc tcactccctt cccccagtca
2281 gtcctgagtc ctgccgtcag actctggcag ggctcccaga ggtaggcctc cagaggcatc
2341 cgccttccca tccacactgc ctttagtggt acgtccgtca tctttttccc tggaagtgac
2401 tttcctcttt tgcatcctgg tggatgctaa tcctgc
＜110〉Attached Tongji Hospital, Tongji Univ.
＜120〉pulmonary thromboembolism related gene and application thereof
<160>142
<210>131
<211>2992
<212>DNA
＜213〉human (Homo sapiens)
<400>131
1 cagcggggcc cgcattgagc atgggcgcgg cggccgtgcg ctggcacttg tgcgtgctgc
61 tggccctggg cacacgcggg cggctggccg ggggcagcgg gctcccaggg tcagtcgacg
121 tggatgagtg ctcagagggc acagatgact gccacatcga tgccatctgt cagaacgcgc
181 ccaagtccta caaatgcctc tgcaagccag gctacaaggg ggaaggcaag cagtgtggag
241 acattgacga gtgtgagaat gactactaca atgggggctg tgtccacgag tgcatcaaca
301 tcccggggaa ctacaggtgt acctgctttg atggcttcat gctggcacac gatggacaca
361 actgcctgga tgtggacgag tgtcaggaca ataatggtgg ctgccagcag atctgcgtca
421 atgccatggg cagctacgag tgtcagtgcc acagtggctt cttccttagt gacaaccagc
481 atacctgcat ccaccgctcc aatgagggta tgaactgcat gaacaaagac catggctgtg
541 cccacatctg ccgggagacg cccaaaggtg gggtggcctg cgactgcagg cccggctttg
601 accttgccca aaaccagaag gactgcacac taacctgtaa ttatggaaac ggaggctgcc
661 agcacagctg tgaggacaca gacacaggcc ccacgtgtgg ttgccaccag aagtacgccc
721 cccactcaga cggtcgcacg tgcatcgaga cgtgcgcagt caataacgga ggctgcgacc
781 ggacatgcaa ggacacagcc actggcgtgc gatgcagctg ccccgttgga ttcacactgc
841 agccggacgg gaagacatgc aaagacatca acgagtgcct ggtcaacaac ggaggctgcg
901 accacttctg ccgcaacacc gtaggcagct tcgagtgcgg ctgccggaag ggctacaagc
961 tgctcaccga cgagcgcacc tgccaggaca tcgacgagtg ctccttcgag cggacctgtg
1021 accacatctg catcaactcc ccgggcagct tccagtgcct gtgtcaccgc ggctacatcc
1081 tctacgggac aacccactgc ggagatgtgg acgagtgcag catgagcaac gggagctgtg
1141 accagggctg cgtcaacacc aagggcagct acgagtgcgt ctgtcccccg gggaggcggc
1201 tccactggaa ccggaaggat tgcgtggaga caggcaagtg tctttctcgc gccaagacct
1261 ccccccgggc ccagctgtcc tgcagcaagg caggcggtgt ggagagctgc ttcctttcct
1321 gcccggctca cacactcttc gtgccagact cggaaaatag ctacgtcctg agctgcggag
1381 ttccagggcc gcagggcaag gcgctgcaga aacgcaacgg caccagctct ggcctcgggc
1441 ccagctgctc agatgccccc accaccccca tcaaacagaa ggcccgcttc aagatccgag
1501 atgccaagtg ccacctccgg ccccacagcc aggcacgagc aaaggagacc gccaggcagc
1561 cgctgctgga ccactgccat gtgactttcg tgaccctcaa gtgtgactcc tccaagaaga
1621 ggcgccgtgg ccgcaagtcc ccatccaagg aggtgtccca cattacagca gagtttgaga
1681 tcgagacaaa gatggaagag gcctcagaca catgcgaagc ggactgcttg cggaagcgag
1741 cagaacagag cctgcaggcc gccatcaaga ccctgcgcaa gtccatcggc cggcagcagt
1801 tctatgtcca ggtctcaggc actgagtacg aggtagccca gaggccagcc aaggcgctgg
1861 aggggcaggg ggcatgtggc gcaggccagg tgctacagga cagcaaatgc gttgcctgtg
1921 ggcctggcac ccacttcggt ggtgagctcg gccagtgtgt gccatgtatg ccaggaacat
1981 accaggacat ggaaggccag ctcagttgca caccgtgccc cagcagcgac gggcttggtc
2041 tgcctggtgc ccgcaacgtg tcggaatgtg gaggccagtg ttctccaggc ttcttctcgg
2101 ccgatggctt caagccctgc caggcctgcc ccgtgggcac gtaccagcct gagcccgggc
2161 gcaccggctg cttcccctgt ggagggggtt tgctcaccaa acacgaaggc accacctcct
2221 tccaggactg cgaggctaaa gtgcactgct cccccggcca ccactacaac accaccaccc
2281 accgctgcat ccgctgcccc gtcggcacct accagcccga gtttggccag aaccactgca
2341 tcacctgtcc gggcaacacc agcacagact tcgatggctc caccaacgtc acacactgca
2401 aaaaccagca ctgcggcggc gagcttggtg actacaccgg ctacatcgag tcccccaact
2461 accctggcga ctacccagcc aacgctgaat gcgtctggca catcgcacct cccccaaagc
2521 gcaggatcct catcgtggtc cctgagatct tcctgcccat cgaggatgag tgcggcgatg
2581 ttctggtcat gaggaagagt gcctctacca cgtccatcac cacctatgag acctgccaga
2641 cctacgagag gcccatcgcc ttcacctccc gctcccgcaa gctctggatc cagttcaaat
2701 ccaatgaagg caacagcggc aaaggcttcc aagtgcccta tgtcacctac gatgaggact
2761 accagcaact catagaggac atcgtgcgcg atgggcgcct gtacgcctcg gagaaccacc
2821 aggaaatttt gaaagacaag aagctgatca aggccctctt cgacgtgctg gcgcatcccc
2881 agaactactt caagtacaca gcccaggaat ccaaggagat gttcccacgg tccttcatca
2941 aactgctgcg ctccaaagtg tctcggttcc tgcggcccta caaataaccg gg
＜110〉Attached Tongji Hospital, Tongji Univ.
＜120〉pulmonary thromboembolism related gene and application thereof
<160>142
<210>132
<211>1785
<212>DNA
＜213〉human (Homo sapiens)
<400>132
1 ccctctgccc gcccccagcc ctcgccccac cctcggcgcc cgcacatctg cctgctcagc
61 tccagacggc gcccggaccc ccgggcgcgg gatccagcca ggtgggagcc ccgcagatga
121 ggtctctgaa ggtgtgcctg aaccagtgcc agcctgccct gtctgcagca tcggcctgat
181 ggggtggtga ctgatccctc agggctccgg agccatgtgg cccaacggca gttccctggg
241 gccctgtttc cggcccacaa acattaccct ggaggagaga cggctgatcg cctcgccctg
301 gttcgccgcc tccttctgcg tggtgggcct ggcctccaac ctgctggccc tgagcgtgct
361 ggcgggcgcg cggcaggggg gttcgcacac gcgctcctcc ttcctcacct tcctctgcgg
421 cctcgtcctc accgacttcc tggggctgct ggtgaccggt accatcgtgg tgtcccagca
481 cgccgcgctc ttcgagtggc acgccgtgga ccctggctgc cgtctctgtc gcttcatggg
541 cgtcgtcatg atcttcttcg gcctgtcccc gctgctgctg ggggccgcca tggcctcaga
601 gcgctacctg ggtatcaccc ggcccttctc gcgcccggcg gtcgcctcgc agcgccgcgc
661 ctgggccacc gtggggctgg tgtgggcggc cgcgctggcg ctgggcctgc tgcccctgct
721 gggcgtgggt cgctacaccg tgcaataccc ggggtcctgg tgcttcctga cgctgggcgc
781 cgagtccggg gacgtggcct tcgggctgct cttctccatg ctgggcggcc tctcggtcgg
841 gctgtccttc ctgctgaaca cggtcagcgt ggccaccctg tgccacgtct accacgggca
901 ggaggcggcc cagcagcgtc cccgggactc cgaggtggag atgatggctc agctcctggg
961 gatcatggtg gtggccagcg tgtgttggct gccccttctg gtcttcatcg cccagacagt
1021 gctgcgaaac ccgcctgcca tgagccccgc cgggcagctg tcccgcacca cggagaagga
1081 gctgctcatc tacttgcgcg tggccacctg gaaccagatc ctggacccct gggtgtatat
1141 cctgttccgc cgcgccgtgc tccggcgtct ccagcctcgc ctcagcaccc ggcccagcgg
1201 agtctcactc tgtggcccag cctggagtac agtggcacga tctcggctca ctgcaacctc
1261 cgcctcccgg gttcaagcga ttctcgtgcc tcagcctccc gagcagctgg gattacaggc
1321 gtaagccact gcgcccggcc ttgcatgctc tttgaccctg aatttgacct acttgctggg
1381 gtacagttgc ttccttttga acctccaaca gggaaggctc tgtccagaaa ggattgaatg
1441 tgaacggggg cacccccttt tcttgccaaa atatatctct gcctttggtt ttattttcct
1501 ttgggtccag aagttttcaa tctctggagt ttgtgcattg ggcctcaccc ggagcagacg
1561 agggcagggc tgggaaggat ggggagggac atagaggatt cggttcctcc cccaccttgt
1621 ttcttgagtg tttcctaatc acttgatggg tggtaccacc tagaattctt ccagcagcct
1681 gtaatgggag ggctacaggt tagccctgga acctgcaatc aaaccacctt tgaatctgtg
1741 tgtcattaaa agtagatata aatgggcaaa aaaaaaaaaa aaaaa
＜110〉Attached Tongji Hospital, Tongji Univ.
＜120〉pulmonary thromboembolism related gene and application thereof
<160>142
<210>133
<211>4434
<212>DNA
＜213〉human (Homo sapiens)
<400>133
1 gccgccctcg ccaccgctcc cggccgccgc gctccggtac acacaggatc cctgctgggc
61 accaacagct ccaccatggg gctggcctgg ggactaggcg tcctgttcct gatgcatgtg
121 tgtggcacca accgcattcc agagtctggc ggagacaaca gcgtgtttga catctttgaa
181 ctcaccgggg ccgcccgcaa ggggtctggg cgccgactgg tgaagggccc cgacccttcc
241 agcccagctt tccgcatcga ggatgccaac ctgatccccc ctgtgcctga tgacaagttc
301 caagacctgg tggatgctgt gcggacagaa aagggtttcc tccttctggc atccctgagg
361 cagatgaaga agacccgggg cacgctgctg gccctggagc ggaaagacca ctctggccag
421 gtcttcagcg tggtgtccaa tggcaaggcg ggcaccctgg acctcagcct gaccgtccaa
481 ggaaagcagc acgtggtgtc tgtggaagaa gctctcctgg caaccggcca gtggaagagc
541 atcaccctgt ttgtgcagga agacagggcc cagctgtaca tcgactgtga aaagatggag
601 aatgctgagt tggacgtccc catccaaagc gtcttcacca gagacctggc cagcatcgcc
661 agactccgca tcgcaaaggg gggcgtcaat gacaatttcc agggggtgct gcagaatgtg
721 aggtttgtct ttggaaccac accagaagac atcctcagga acaaaggctg ctccagctct
781 accagtgtcc tcctcaccct tgacaacaac gtggtgaatg gttccagccc tgccatccgc
841 actaactaca ttggccacaa gacaaaggac ttgcaagcca tctgcggcat ctcctgtgat
901 gagctgtcca gcatggtcct ggaactcagg ggcctgcgca ccattgtgac cacgctgcag
961 gacagcatcc gcaaagtgac tgaagagaac aaagagttgg ccaatgagct gaggcggcct
1021 cccctatgct atcacaacgg agttcagtac agaaataacg aggaatggac tgttgatagc
1081 tgcactgagt gtcactgtca gaactcagtt accatctgca aaaaggtgtc ctgccccatc
1141 atgccctgct ccaatgccac agttcctgat ggagaatgct gtcctcgctg ttggcccagc
1201 gactctgcgg acgatggctg gtctccatgg tccgagtgga cctcctgttc tacgagctgt
1261 ggcaatggaa ttcagcagcg cggccgctcc tgcgatagcc tcaacaaccg atgtgagggc
1321 tcctcggtcc agacacggac ctgccacatt caggagtgtg acaagagatt taaacaggat
1381 ggtggctgga gccactggtc cccgtggtca tcttgttctg tgacatgtgg tgatggtgtg
1441 atcacaagga tccggctctg caactctccc agcccccaga tgaacgggaa accctgtgaa
1501 ggcgaagcgc gggagaccaa agcctgcaag aaagacgcct gccccatcaa tggaggctgg
1561 ggtccttggt caccatggga catctgttct gtcacctgtg gaggaggggt acagaaacgt
1621 agtcgtctct gcaacaaccc cacaccccag tttggaggca aggactgcgt tggtgatgta
1681 acagaaaacc agatctgcaa caagcaggac tgtccaattg atggatgcct gtccaatccc
1741 tgctttgccg gcgtgaagtg tactagctac cctgatggca gctggaaatg tggtgcttgt
1801 ccccctggtt acagtggaaa tggcatccag tgcacagatg ttgatgagtg caaagaagtg
1861 cctgatgcct gcttcaacca caatggagag caccggtgtg agaacacgga ccccggctac
1921 aactgcctgc cctgcccccc acgcttcacc ggctcacagc ccttcggcca gggtgtcgaa
1981 catgccacgg ccaacaaaca ggtgtgcaag ccccgtaacc cctgcacgga tgggacccac
2041 gactgcaaca agaacgccaa gtgcaactac ctgggccact atagcgaccc catgtaccgc
2101 tgcgagtgca agcctggcta cgctggcaat ggcatcatct gcggggagga cacagacctg
2161 gatggctggc ccaatgagaa cctggtgtgc gtggccaatg cgacttacca ctgcaaaaag
2221 gataattgcc ccaaccttcc caactcaggg caggaagact atgacaagga tggaattggt
2281 gatgcctgtg atgatgacga tgacaatgat aaaattccag atgacaggga caactgtcca
2341 ttccattaca acccagctca gtatgactat gacagagatg atgtgggaga ccgctgtgac
2401 aactgtccct acaaccacaa cccagatcag gcagacacag acaacaatgg ggaaggagac
2461 gcctgtgctg cagacattga tggagacggt atcctcaatg aacgggacaa ctgccagtac
2521 gtctacaatg tggaccagag agacactgat atggatgggg ttggagatca gtgtgacaat
2581 tgccccttgg aacacaatcc ggatcagctg gactctgact cagaccgcat tggagatacc
2641 tgtgacaaca atcaggatat tgatgaagat ggccaccaga acaatctgga caactgtccc
2701 tatgtgccca atgccaacca ggctgaccat gacaaagatg gcaagggaga tgcctgtgac
2761 cacgatgatg acaacgatgg cattcctgat gacaaggaca actgcagact cgtgcccaat
2821 cccgaccaga aggactctga cggcgatggt cgaggtgatg cctgcaaaga tgattttgac
2881 catgacagtg tgccagacat cgatgacatc tgtcctgaga atgttgacat cagtgagacc
2941 gatttccgcc gattccagat gattcctctg gaccccaaag ggacatccca aaatgaccct
3001 aactgggttg tacgccatca gggtaaagaa ctcgtccaga ctgtcaactg tgatcctgga
3061 ctcgctgtag gttatgatga gtttaatgct gtggacttca gtggcacctt cttcatcaac
3121 accgaaaggg acgatgacta tgctggattt gtctttggct accagtccag cagccgcttt
3181 tatgttgtga tgtggaagca agtcacccag tcctactggg acaccaaccc cacgagggct
3241 cagggatact cgggcctttc tgtgaaagtt gtaaactcca ccacagggcc tggcgagcac
3301 ctgcggaacg ccctgtggca cacaggaaac acccctggcc aggtgcgcac cctgtggcat
3361 gaccctcgtc acataggctg gaaagatttc accgcctaca gatggcgtct cagccacagg
3421 ccaaagacgg gtttcattag agtggtgatg tatgaaggga agaaaatcat ggctgactca
3481 ggacccatct atgataaaac ctatgctggt ggtagactag ggttgtttgt cttctctcaa
3541 gaaatggtgt tcttctctga cctgaaatac gaatgtagag atccctaatc atcaaattgt
3601 tgattgaaag actgatcata aaccaatgct ggtattgcac cttctggaac tatgggcttg
3661 agaaaacccc caggatcact tctccttggc ttccttcttt tctgtgcttg catcagtgtg
3721 gactcctaga acgtgcgacc tgcctcaaga aaatgcagtt ttcaaaaaca gactcagcat
3781 tcagcctcca atgaataaga catcttccaa gcatataaac aattgctttg gtttcctttt
3841 gaaaaagcat ctacttgctt cagttgggaa ggtgcccatt ccactctgcc tttgtcacag
3901 agcagggtgc tattgtgagg ccatctctga gcagtggact caaaagcatt ttcaggcatg
3961 tcagagaagg gaggactcac tagaattagc aaacaaaacc accctgacat cctccttcag
4021 gaacacgggg agcagaggcc aaagcactaa ggggagggcg catacccgag acgattatat
4081 gaagaaaata tggaggaact gttacatgtt cggtactaag tcattttaag gggattgaaa
4141 gactattgct ggatttcatg atgctgactg gcgttagctg attaacccat gtaaataggc
4201 acttaaatag aagcaggaaa gggagacaaa gactggcttc tggacttcct ccctgatccc
4261 cacccttact catcacctgc agtggccaga attagggaat cagaatcgaa accagtgtaa
4321 ggcagtgctg gctgccattg cctggtcaca ttgaaattgg tggcttcatt ctagatgtag
4381 cttgtgcaga tgtagcagga aaataggaaa acctaccatc tcagtgagca ccag
＜110〉Attached Tongji Hospital, Tongji Univ.
＜120〉pulmonary thromboembolism related gene and application thereof
<160>142
<210>134
<211>521
<212>DNA
＜213〉human (Homo sapiens)
<400>134
1 ggacaaggct actataacaa gcctgtgggg caaggtgaat gtggaagatg ctggaggaga
61 aaccctggga aggctcctgg ttgtctaccc atggacccag aggttctttg acagctttgg
121 caacctgtcc tctgcctctg ccatcatggg caaccccaaa gtcaaggcac atggcaagaa
181 ggtgctgact tccttgggag atgccataaa gcacctggat gatctcaagg gcacctttgc
241 ccagctgagt gaactgcact gtgacaagct gcatgtggat cctgagaact tcaagctcct
301 gggaaatgtg ctggtgaccg ttttggcaat ccatttcggc aaagaattca cccctgaggt
361 gcaggcttcc tggcagaaga tggcagaaga tggtgactgg agtggccagt gccctgtcct
421 ccagatacta ctgagctcac tgcctatgat gcagagcttt caaggatagg ctttattctg
481 caagcaatac aaataataaa tctattctgc taagagatca c
＜110〉Attached Tongji Hospital, Tongji Univ.
＜120〉pulmonary thromboembolism related gene and application thereof
<160>142
<210>135
<211>1809
<212>DNA
＜213〉human (Homo sapiens)
<400>135
1 agaagatcct gggttctgtg catccgtctg tctgaccatc cctctcaatc ttccctgccc
61 aggactggcc atactgccac cgcacacgtg cacacacgcc aacaggcatc tgccatgctg
121 gcatctctat aagggctcca gtccagagac cctgggccat tgaacttgct cctcaggcag
181 aggctgagtc cgcacatcac ctccaggccc tcagaacacc tgccccagcc ccaccatgct
241 catggcgtcc accacttccg ctgtgcctgg gcatccctct ctgcccagcc tgcccagcaa
301 cagcagccag gagaggccac tggacacccg ggacccgctg ctagcccggg cggagctggc
361 gctgctctcc atagtctttg tggctgtggc cctgagcaat ggcctggtgc tggcggccct
421 agctcggcgg ggccggcggg gccactgggc acccatacac gtcttcattg gccacttgtg
481 cctggccgac ctggccgtgg ctctgttcca agtgctgccc cagctggcct ggaaggccac
541 cgaccgcttc cgtgggccag atgccctgtg tcgggccgtg aagtatctgc agatggtggg
601 catgtatgcc tcctcctaca tgatcctggc catgacgctg gaccgccacc gtgccatctg
661 ccgtcccatg ctggcgtacc gccatggaag tggggctcac tggaaccggc cggtgctagt
721 ggcttgggcc ttctcgctcc ttctcagcct gccccagctc ttcatcttcg cccagcgcaa
781 cgtggaaggt ggcagcgggg tcactgactg ctgggcctgc tttgcggagc cctggggccg
841 tcgcacctat gtcacctgga ttgccctgat ggtgttcgtg gcacctaccc tgggtatcgc
901 cgcctgccag gtgctcatct tccgggagat tcatgccagt ctggtgccag ggccatcaga
961 gaggcctggg gggcgccgca ggggacgccg gacaggcagc cccggtgagg gagcccacgt
1021 gtcagcagct gtggccaaga ctgtgaggat gacgctagtg attgtggtcg tctatgtgct
1081 gtgctgggca cccttcttcc tggtgcagct gtgggccgcg tgggacccgg aggcacctct
1141 ggaaggggcg ccctttgtgc tactcatgtt gctggccagc ctcaacagct gcaccaaccc
1201 ctggatctat gcatctttca gcagcagcgt gtcctcagag ctgcgaagct tgctctgctg
1261 tgcccgggga cgcaccccac ccagcctggg tccccaagat gagtcctgca ccaccgccag
1321 ctcctccctg gccaaggaca cttcatcgtg aggagctgtt gggtgtcttg cctctagagg
1381 ctttgagaag ctcagctgcc ttcctggggc tggtcctggg agccactggg agggggaccc
1441 gtggagaatt ggccagagcc tgtggccccg aggctgggac actgtgtggc cctggacaag
1501 ccacagcccc tgcctgggtc tccacatccc cagctgtatg aggagagctt caggccccag
1561 gactgtgggg gcccctcagg tcagctcact gagctgggtg taggaggggc tgcagcagag
1621 gcctgaggag tggcaggaaa gagggagcag gtgcccccag gtgagacagc ggtcccaggg
1681 gcctgaaaag gaaggaccag gctggggcca ggggaccttc ctgtctccgc ctttctaatc
1741 cctccctcct cattctctcc ctaataaaaa ttggagctct tttccacatg gcaaggggtc
1801 tccttggaa
＜110〉Attached Tongji Hospital, Tongji Univ.
＜120〉pulmonary thromboembolism related gene and application thereof
<160>142
<210>136
<211>1600
<212>DNA
＜213〉human (Homo sapiens)
<400>136
1 gccccgccgc cggcagtgga ccgctgtgcg cgaaccctga accctacggt cccgacccgc
61 gggcgaggcc gggtacctgg gctgggatcc ggagcaagcg ggcgagggca gcgccctaag
121 caggcccgga gcgatggcag ccttgatgac cccgggaacc ggggccccac ccgcgcctgg
181 tgacttctcc ggggaaggga gccagggact tcccgaccct tcgccagagc ccaagcagct
241 cccggagctg atccgcatga agcgagacgg aggccgcctg agcgaagcgg acatcagggg
301 cttcgtggcc gctgtggtga atgggagcgc gcagggcgca cagatcgggg ccatgctgat
361 ggccatccga cttcggggca tggatctgga ggagacctcg gtgctgaccc aggccctggc
421 tcagtcggga cagcagctgg agtggccaga ggcctggcgc cagcagcttg tggacaagca
481 ttccacaggg ggtgtgggtg acaaggtcag cctggtcctc gcacctgccc tggcggcatg
541 tggctgcaag gtgccaatga tcagcggacg tggtctgggg cacacaggag gcaccttgga
601 taagctggag tctattcctg gattcaatgt catccagagc ccagagcaga tgcaagtgct
661 gctggaccag gcgggctgct gtatcgtggg tcagagtgag cagctggttc ctgcggacgg
721 aatcctatat gcagccagag atgtgacagc caccgtggac agcctgccac tcatcacagc
781 ctccattctc agtaagaaac tcgtggaggg gctgtccgct ctggtggtgg acgttaagtt
841 cggaggggcc gccgtcttcc ccaaccagga gcaggcccgg gagctggcaa agacgctggt
901 tggcgtggga gccagcctag ggcttcgggt cgcggcagcg ctgaccgcca tggacaagcc
961 cctgggtcgc tgcgtgggcc acgccctgga ggtggaggag gcgctgctct gcatggacgg
1021 cgcaggcccg ccagacttaa gggacctggt caccacgctc gggggcgccc tgctctggct
1081 cagcggacac gcggggactc aggctcaggg cgctgcccgg gtggccgcgg cgctggacga
1141 cggctcggcc cttggccgct tcgagcggat gctggcggcg cagggcgtgg atcccggtct
1201 ggcccgagcc ctgtgctcgg gaagtcccgc agaacgccgg cagctgctgc ctcgcgcccg
1261 ggagcaggag gagctgctgg cgcccgcaga tggcaccgtg gagctggtcc gggcgctgcc
1321 gctggcgctg gtgctgcacg agctcggggc cgggcgcagc cgcgctgggg agccgctccg
1381 cctgggggtg ggcgcagagc tgctggtcga cgtgggtcag aggctgcgcc gtgggacccc
1441 ctggctccgc gtgcaccggg acggccccgc gctcagcggc ccgcagagcc gcgccctgca
1501 ggaggcgctc gtactctccg accgcgcgcc attcgccgcc ccctcgccct tcgcagagct
1561 cgttctgccg ccgcagcaat aaagctcctt tgccgcgaaa
＜110〉Attached Tongji Hospital, Tongji Univ.
＜120〉pulmonary thromboembolism related gene and application thereof
<160>142
<210>137
<211>2048
<212>DNA
＜213〉human (Homo sapiens)
<400>137
1 ctattgatct ggactcctgg ataggcagct ggaccaacgg acggacgcca tgagggctct
61 gctgctcctg gggttcctgc tggtgagctt ggagtcaaca ctttcgattc caccttggga
121 agcccccaag gagcataagt acaaagctga agagcacaca gtcgttctca ctgtcaccgg
181 ggagccctgc cacttcccct tccagtacca ccggcagctg taccacaaat gtacccacaa
241 gggccggcca ggccctcagc cctggtgtgc taccaccccc aactttgatc aggaccagcg
301 atggggatac tgtttggagc ccaagaaagt gaaagaccac tgcagcaaac acagcccctg
361 ccagaaagga gggacctgtg tgaacatgcc aagcggcccc cactgtctct gtccacaaca
421 cctcactgga aaccactgcc agaaagagaa gtgctttgag cctcagcttc tccggttttt
481 ccacaagaat gagatatggt atagaactga gcaagcagct gtggccagat gccagtgcaa
541 gggtcctgat gcccactgcc agcggctggc cagccaggcc tgccgcacca acccgtgcct
601 ccatgggggt cgctgcctag aggtggaggg ccaccgcctg tgccactgcc cggtgggcta
661 caccggaccc ttctgcgacg tggacaccaa ggcaagctgc tatgatggcc gcgggctcag
721 ctaccgcggc ctggccagga ccacgctctc gggtgcgccc tgtcagccgt gggcctcgga
781 ggccacctac cggaacgtga ctgccgagca agcgcggaac tggggactgg gcggccacgc
841 cttctgccgg aacccggaca acgacatccg cccgtggtgc ttcgtgctga accgcgaccg
901 gctgagctgg gagtactgcg acctggcaca gtgccagacc ccaacccagg cggcgcctcc
961 gaccccggtg tcccctaggc ttcatgtccc actcatgccc gcgcagccgg caccgccgaa
1021 gcctcagccc acgacccgga ccccgcctca gtcccagacc ccgggagcct tgccggcgaa
1081 gcgggagcag ccgccttccc tgaccaggaa cggcccactg agctgcgggc agcggctccg
1141 caagagtctg tcttcgatga cccgcgtcgt tggcgggctg gtggcgctac gcggggcgca
1201 cccctacatc gccgcgctgt actggggcca cagtttctgc gccggcagcc tcatcgcccc
1261 ctgctgggtg ctgacggccg ctcactgcct gcaggaccgg cccgcacccg aggatctgac
1321 ggtggtgctc ggccaggaac gccgtaacca cagctgtgag ccgtgccaga cgttggccgt
1381 gcgctcctac cgcttgcacg aggccttctc gcccgtcagc taccagcacg acctggctct
1441 gttgcgcctt caggaggatg cggacggcag ctgcgcgctc ctgtcgcctt acgttcagcc
1501 ggtgtgcctg ccaagcggcg ccgcgcgacc ctccgagacc acgctctgcc aggtggccgg
1561 ctggggccac cagttcgagg gggcggagga atatgccagc ttcctgcagg aggcgcaggt
1621 accgttcctc tccctggagc gctgctcagc cccggacgtg cacggatcct ccatcctccc
1681 cggcatgctc tgcgcagggt tcctcgaggg cggcaccgat gcgtgccagg gtgattccgg
1741 aggcccgctg gtgtgtgagg accaagctgc agagcgccgg ctcaccctgc aaggcatcat
1801 cagctgggga tcgggctgtg gtgaccgcaa caagccaggc gtctacaccg atgtggccta
1861 ctacctggcc tggatccggg agcacaccgt ttcctgattg ctcagggact catctttccc
1921 tccttggtga ttccgcagtg agagagtggc tggggcatgg aaggcaagat tgtgtcccat
1981 tcccccagtg cggccagctc cgcgccagga tggcgaggaa ctcaataaag tgctttgaaa
2041 atgctgag
＜110〉Attached Tongji Hospital, Tongji Univ.
＜120〉pulmonary thromboembolism related gene and application thereof
<160>142
<210>138
<211>955
<212>DNA
＜213〉human (Homo sapiens)
<400>138
1 agtaagccgg gctgccgtct tctcgccatg ggctccgggc cgcgcggggc gctgagctta
61 ctgctcctgc tgctggcccc gccgagccgc ccggccgcag gttgcccggc gccctgtagc
121 tgcgcgggga cgctcgtgga ctgcgggcgc cgcgggctga cttgggcctc gctgccgacc
181 gccttccctg tcgacacaac cgagctggtg ctgaccggca acaacctgac ggcgctgccg
241 ccggggctgc tggacgcgct gcccgcgctg cgcaccgcac acctgggcgc caacccctgg
301 cgctgcgact gccgccttgt gccgctgcgc gcctggctgg ccggccgccc cgagcgtgcg
361 ccctaccgcg acctgcgttg cgtggcgccc ccagcgctgc gcggccgcct gctgccctat
421 ctggccgagg acgagctgcg cgccgcttgc gctcccggcc cgctctgctg gggggcgctg
481 gcggcgcagc ttgcgctgct gggccttggg ctgctgcacg cgttgctgct ggtgctgctg
541 ctgtgccgcc tgcggaggct gcgggcccgg gcccgcgctc gcgccgcagc ccggctgtcg
601 ctgaccgacc cgctggtggc cgagcgagcc ggaaccgacg agtcctgagg agagaaccgg
661 tgcgtcctga ggagagaacc ggcgctgggc aacacgggcc tgcaaactcg acaggaccct
721 gcccgagggg ccctcgcgcc aacctggacc ggtccccgcc tcctccgctg cccaatctct
781 cagacccacc ccacctgcag gcccagacca cgtgggacag aactcctgcc caccctaccc
841 cgagggaggc gaacccgcac ttccaggctt gggaggacca tggggcacaa tgcggtccag
901 accctgctgc gtctcccttc caaactctgg tgctgaataa acccttctga tctgg
＜110〉Attached Tongji Hospital, Tongji Univ.
＜120〉pulmonary thromboembolism related gene and application thereof
<160>142
<210>139
<211>900
<212>DNA
＜213〉human (Homo sapiens)
<400>139
1 gccaggacct ttcaggccag acaggagcac ctgaccaaag gcttcacagc cgccctcacc
61 gcccggcctt ctacggtgtc cagagacagt tagccaggcc tgggctgggc acactccacc
121 ttccctagtc accagctggt ttcccagagg agaaggctga gacccgagaa gggagccagc
181 ctgtcccatg cctgcctggg gagccctgtt cctgctctgg gccacagcag aggccaccaa
241 ggactgcccc agcccatgta cctgccgcgc cctggaaacc atggggctgt gggtggactg
301 caggggccac ggactcacgg ccctgcctgc cctgccggcc cgcacccgcc accttctgct
361 ggccaacaac agccttcagt ccgtgccccc gggagccttt gaccacctgc cccagctgca
421 gaccctcgat gtgacgcaga acccctggca ctgtgactgc agcctcacct atctgcgcct
481 ctggctggag gaccgcacgc ccgaggccct gctgcaggtc cgctgtgcca gccccagcct
541 cgctgcccat ggcccgctgg gccggctgac aggctaccag ctgggcagct gtggctggca
601 gctgcaggcg tcctgggtgc gcccgggggt cttgtgggac gtggcgctgg tcgccgtggc
661 cgcgctgggc ctggctcttc tggctggcct gctgtgtgcc accacagagg ccctggattg
721 agccaggccc ccagaacccc tggctccagg ccagggggcc agtccctgag gcaggtcccc
781 agactccacc aagcctggtc agcccaaacc accagaagcc cagaataaac tggcagctca
841 gctgttttat ataaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa
＜110〉Attached Tongji Hospital, Tongji Univ.
＜120〉pulmonary thromboembolism related gene and application thereof
<160>142
<210>140
<211>576
<212>DNA
＜213〉human (Homo sapiens)
<400>140
1 actcttctgg tccccacaga ctcagagaga acccaccatg gtgctgtctc ctgccgacaa
61 gaccaacgtc aaggccgcct ggggtaaggt cggcgcgcac gctggcgagt atggtgcgga
121 ggccctggag aggatgttcc tgtccttccc caccaccaag acctacttcc cgcacttcga
181 cctgagccac ggctctgccc aggttaaggg ccacggcaag aaggtggccg acgcgctgac
241 caacgccgtg gcgcacgtgg acgacatgcc caacgcgctg tccgccctga gcgacctgca
301 cgcgcacaag cttcgggtgg acccggtcaa cttcaagctc ctaagccact gcctgctggt
361 gaccctggcc gcccacctcc ccgccgagtt cacccctgcg gtgcacgcct ccctggacaa
421 gttcctggct tctgtgagca ccgtgctgac ctccaaatac cgttaagctg gagcctcggt
481 ggccatgctt cttgcccctt gggcctcccc ccagcccctcc tccccttcc tgcacccgta
541 cccccgtggt ctttgaataa agtctgagtg ggcggc
＜110〉Attached Tongji Hospital, Tongji Univ.
＜120〉pulmonary thromboembolism related gene and application thereof
<160>142
<210>141
<211>575
<212>DNA
＜213〉human (Homo sapiens)
<400>141
1 actcttctgg tccccacaga ctcagagaga acccaccatg gtgctgtctc ctgccgacaa
61 gaccaacgtc aaggccgcct ggggtaaggt cggcgcgcac gctggcgagt atggtgcgga
121 ggccctggag aggatgttcc tgtccttccc caccaccaag acctacttcc cgcacttcga
181 cctgagccac ggctctgccc aggttaaggg ccacggcaag aaggtggccg acgcgctgac
241 caacgccgtg gcgcacgtgg acgacatgcc caacgcgctg tccgccctga gcgacctgca
301 cgcgcacaag cttcgggtgg acccggtcaa cttcaagctc ctaagccact gcctgctggt
361 gaccctggcc gcccacctcc ccgccgagtt cacccctgcg gtgcacgcct ccctggacaa
421 gttcctggct tctgtgagca ccgtgctgac ctccaaatac cgttaagctg gagcctcggt
481 agccgttcct cctgcccgct gggcctccca acgggccctc ctcccctcct tgcaccggcc
541 cttcctggtc tttgaataaa gtctgagtgg gcggc
＜110〉Attached Tongji Hospital, Tongji Univ.
＜120〉pulmonary thromboembolism related gene and application thereof
<160>142
<210>142
<211>147
<212>DNA
＜213〉human (Homo sapiens)
<400>142
1 gaatgtggca aagcctttaa cagttctcaa atcttaccta cacataaaaa aattcataat
61 ggagagcaac cctacatatg tgaagaatgt gtgaaatttt ttacccaatc ctcaaccctt
121 actacacata agagaattca tactgag
Claims (2)
1, one group of gene relevant with PTE is characterized in that having the NO:1 as SEQ ID, SEQ ID NO:2, SEQ ID NO:3, SEQ ID NO:4, SEQ ID NO:5, SEQ IDNO:6, SEQ ID NO:7, SEQ ID NO:8, SEQ ID NO:9, SEQ ID NO:10, SEQ ID NO:11, SEQ ID NO:12, SEQ ID NO:13, SEQ ID NO:14, SEQID NO:15, SEQ ID NO:16, SEQ ID NO:17, SEQ ID NO:18, SEQ IDNO:19, SEQ ID NO:20, SEQ ID NO:21, SEQ ID NO:22, SEQ ID NO:23, SEQ ID NO:24, SEQ ID NO:25, SEQ ID NO:26, SEQ ID NO:27, SEQ ID NO:28, SEQ ID NO:29, SEQ ID NO:30, SEQ ID NO:31, SEQID NO:32, SEQ ID NO:33, SEQ ID NO:34, SEQ ID NO:35, SEQ IDNO:36, SEQ ID NO:37, SEQ ID NO:38, SEQ ID NO:39, SEQ ID NO:40, SEQ ID NO:41, SEQ ID NO:42, SEQ ID NO:43, SEQ ID NO:44, SEQ ID NO:45, SEQ ID NO:46, SEQ ID NO:47, SEQ ID NO:48, SEQID NO:49, SEQ ID NO:50, SEQ ID NO:51, SEQ ID NO:52, SEQ IDNO:53, SEQ ID NO:54, SEQ ID NO:55, SEQ ID NO:56, SEQ ID NO:57, SEQ ID NO:58, SEQ ID NO:59, SEQ ID NO:60, SEQ ID NO:61, SEQ ID NO:62, SEQ ID NO:63, SEQ ID NO:64, SEQ ID NO:65, SEQID NO:66, SEQID NO:67, SEQ ID NO:68, SEQ ID NO:69, SEQ IDNO:70, SEQ ID NO:71, SEQ ID NO:72, SEQ ID NO:73, SEQ ID NO:74, SEQ ID NO:75, SEQ ID NO:76, SEQ ID NO:77, SEQ ID NO:78, SEQ ID NO:79, SEQ ID NO:80, SEQ ID NO:81, SEQ ID NO:82, SEQID NO:83, SEQ ID NO:84, SEQ ID NO:85, SEQ ID NO:86, SEQ IDNO:87, SEQ ID NO:88, SEQ ID NO:89, SEQ ID NO:90, SEQ ID NO:91, SEQ ID NO:92, SEQ ID NO:93, SEQ ID NO:94, SEQ ID NO:95, SEQ ID NO:96, SEQ ID NO:97, SEQ ID NO:98, SEQ ID NO:99, SEQID NO:100, SEQ ID NO:101, SEQ ID NO:102, SEQ ID NO:103, SEQID NO:104, SEQ ID NO:105, SEQ ID NO:106, SEQ ID NO:107, SEQID NO:108, SEQ ID NO:109, SEQ ID NO:110, SEQ ID NO:111, SEQID NO:112, SEQ ID NO:113, SEQ ID NO:114, SEQ ID NO:115, SEQID NO:116, SEQ ID NO:117, SEQ ID NO:118, SEQ ID NO:119, SEQID NO:120, SEQ ID NO:121, SEQ ID NO:122, SEQ ID NO:123, SEQID NO:124, SEQ ID NO:125, SEQ ID NO:126, SEQ ID NO:127, SEQID NO:128, SEQ ID NO:129, SEQ ID NO:130, SEQ ID NO:131, SEQID NO:132, SEQ ID NO:133, SEQ ID NO:134, SEQ ID NO:135, SEQID NO:136, SEQ ID NO:137, SEQ ID NO:138, SEQ ID NO:139, SEQID NO:140, full-length gene shown in SEQ ID NO:141 and the SEQ ID NO:142.
2, the application of the gene that PTE as claimed in claim 1 is relevant in the test kit of preparation diagnosis PTE.
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| CN 200510111646 CN1986793A (en) | 2005-12-19 | 2005-12-19 | Pulmonary thromboembolism related gene and its application |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107012238A (en) * | 2017-05-04 | 2017-08-04 | 上海交通大学医学院附属瑞金医院 | Easy thrombus related gene mutation detection kit |
| CN109652525A (en) * | 2018-11-30 | 2019-04-19 | 深圳市人民医院 | Pulmonary thromboembolism gene panel kit and its application |
| CN114672548A (en) * | 2022-03-10 | 2022-06-28 | 华捷生物科技(青岛)有限公司 | Human venous thrombosis risk gene polymorphism detection kit, process and application |
-
2005
- 2005-12-19 CN CN 200510111646 patent/CN1986793A/en active Pending
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107012238A (en) * | 2017-05-04 | 2017-08-04 | 上海交通大学医学院附属瑞金医院 | Easy thrombus related gene mutation detection kit |
| CN107012238B (en) * | 2017-05-04 | 2020-11-24 | 上海交通大学医学院附属瑞金医院 | Easy thrombus related gene mutation detection kit |
| CN109652525A (en) * | 2018-11-30 | 2019-04-19 | 深圳市人民医院 | Pulmonary thromboembolism gene panel kit and its application |
| CN114672548A (en) * | 2022-03-10 | 2022-06-28 | 华捷生物科技(青岛)有限公司 | Human venous thrombosis risk gene polymorphism detection kit, process and application |
| CN114672548B (en) * | 2022-03-10 | 2024-04-19 | 华捷生物科技(青岛)有限公司 | Human venous thrombosis risk gene PAI-1, THBD and PROC gene polymorphism detection kit, and preparation method and application thereof |
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