CN1980888B - Modafinil compositions - Google Patents
Modafinil compositions Download PDFInfo
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- CN1980888B CN1980888B CN2005800041104A CN200580004110A CN1980888B CN 1980888 B CN1980888 B CN 1980888B CN 2005800041104 A CN2005800041104 A CN 2005800041104A CN 200580004110 A CN200580004110 A CN 200580004110A CN 1980888 B CN1980888 B CN 1980888B
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- Prior art keywords
- provigil
- medicine
- wantonly
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- composition
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- WXMKPNITSTVMEF-UHFFFAOYSA-M sodium benzoate Chemical compound [Na+].[O-]C(=O)C1=CC=CC=C1 WXMKPNITSTVMEF-UHFFFAOYSA-M 0.000 description 1
- 239000004299 sodium benzoate Substances 0.000 description 1
- 235000010234 sodium benzoate Nutrition 0.000 description 1
- 229940005573 sodium fumarate Drugs 0.000 description 1
- 235000019294 sodium fumarate Nutrition 0.000 description 1
- 239000007901 soft capsule Substances 0.000 description 1
- 239000011973 solid acid Substances 0.000 description 1
- 238000007614 solvation Methods 0.000 description 1
- 229950006451 sorbitan laurate Drugs 0.000 description 1
- 235000011067 sorbitan monolaureate Nutrition 0.000 description 1
- 239000000600 sorbitol Substances 0.000 description 1
- 230000003595 spectral effect Effects 0.000 description 1
- 238000001228 spectrum Methods 0.000 description 1
- 239000007921 spray Substances 0.000 description 1
- 229910001220 stainless steel Inorganic materials 0.000 description 1
- 239000010935 stainless steel Substances 0.000 description 1
- 239000008117 stearic acid Substances 0.000 description 1
- 125000004079 stearyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 description 1
- 230000000638 stimulation Effects 0.000 description 1
- 238000003860 storage Methods 0.000 description 1
- 238000010254 subcutaneous injection Methods 0.000 description 1
- 239000007929 subcutaneous injection Substances 0.000 description 1
- 239000000758 substrate Substances 0.000 description 1
- KDYFGRWQOYBRFD-UHFFFAOYSA-L succinate(2-) Chemical compound [O-]C(=O)CCC([O-])=O KDYFGRWQOYBRFD-UHFFFAOYSA-L 0.000 description 1
- 150000003457 sulfones Chemical class 0.000 description 1
- 239000000829 suppository Substances 0.000 description 1
- 238000009492 tablet coating Methods 0.000 description 1
- 239000002700 tablet coating Substances 0.000 description 1
- ZZIZZTHXZRDOFM-XFULWGLBSA-N tamsulosin hydrochloride Chemical compound [H+].[Cl-].CCOC1=CC=CC=C1OCCN[C@H](C)CC1=CC=C(OC)C(S(N)(=O)=O)=C1 ZZIZZTHXZRDOFM-XFULWGLBSA-N 0.000 description 1
- 229940095064 tartrate Drugs 0.000 description 1
- 150000004685 tetrahydrates Chemical class 0.000 description 1
- 229940126585 therapeutic drug Drugs 0.000 description 1
- 229960000984 tocofersolan Drugs 0.000 description 1
- AOBORMOPSGHCAX-DGHZZKTQSA-N tocofersolan Chemical compound OCCOC(=O)CCC(=O)OC1=C(C)C(C)=C2O[C@](CCC[C@H](C)CCC[C@H](C)CCCC(C)C)(C)CCC2=C1C AOBORMOPSGHCAX-DGHZZKTQSA-N 0.000 description 1
- 231100000331 toxic Toxicity 0.000 description 1
- 230000002588 toxic effect Effects 0.000 description 1
- 231100000419 toxicity Toxicity 0.000 description 1
- 230000001988 toxicity Effects 0.000 description 1
- VZCYOOQTPOCHFL-UHFFFAOYSA-N trans-butenedioic acid Natural products OC(=O)C=CC(O)=O VZCYOOQTPOCHFL-UHFFFAOYSA-N 0.000 description 1
- 238000012546 transfer Methods 0.000 description 1
- QORWJWZARLRLPR-UHFFFAOYSA-H tricalcium bis(phosphate) Chemical compound [Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O QORWJWZARLRLPR-UHFFFAOYSA-H 0.000 description 1
- 235000019731 tricalcium phosphate Nutrition 0.000 description 1
- 229940117013 triethanolamine oleate Drugs 0.000 description 1
- 150000004684 trihydrates Chemical class 0.000 description 1
- MDYZKJNTKZIUSK-UHFFFAOYSA-N tyloxapol Chemical compound O=C.C1CO1.CC(C)(C)CC(C)(C)C1=CC=C(O)C=C1 MDYZKJNTKZIUSK-UHFFFAOYSA-N 0.000 description 1
- 229920001664 tyloxapol Polymers 0.000 description 1
- 229960004224 tyloxapol Drugs 0.000 description 1
- 238000003828 vacuum filtration Methods 0.000 description 1
- 239000011709 vitamin E Substances 0.000 description 1
- 229940046009 vitamin E Drugs 0.000 description 1
- 235000019165 vitamin E Nutrition 0.000 description 1
- 239000000811 xylitol Substances 0.000 description 1
- 235000010447 xylitol Nutrition 0.000 description 1
- HEBKCHPVOIAQTA-SCDXWVJYSA-N xylitol Chemical compound OC[C@H](O)[C@@H](O)[C@H](O)CO HEBKCHPVOIAQTA-SCDXWVJYSA-N 0.000 description 1
- 229960002675 xylitol Drugs 0.000 description 1
- 239000002076 α-tocopherol Substances 0.000 description 1
- 235000004835 α-tocopherol Nutrition 0.000 description 1
Images
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Abstract
Description
Parameter | The setting of using |
Duration of contact (s) | 2.0 |
Frequency of |
10 |
Laser source wavelength (nm) | 785 |
Laser power (%) | 100 |
Iris shape | Pin hole |
Aperture scale (um) | 100 |
Spectral range | 104-3428 |
Stop position | Single |
Temperature during collection (℃) | 24.0 |
Claims (7)
Applications Claiming Priority (18)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US54275204P | 2004-02-06 | 2004-02-06 | |
US60/542,752 | 2004-02-06 | ||
US56041104P | 2004-04-06 | 2004-04-06 | |
US60/560,411 | 2004-04-06 | ||
US57341204P | 2004-05-21 | 2004-05-21 | |
US60/573,412 | 2004-05-21 | ||
US60/579,176 | 2004-06-12 | ||
US58199204P | 2004-06-22 | 2004-06-22 | |
US60/581,992 | 2004-06-22 | ||
US58675204P | 2004-07-09 | 2004-07-09 | |
US60/586,752 | 2004-07-09 | ||
US58823604P | 2004-07-15 | 2004-07-15 | |
US60/588,236 | 2004-07-15 | ||
USPCT/US04/29013 | 2004-09-04 | ||
PCT/US2004/029013 WO2005023198A2 (en) | 2003-09-04 | 2004-09-04 | Modafinil compositions |
US63178604P | 2004-11-30 | 2004-11-30 | |
US60/631,786 | 2004-11-30 | ||
PCT/US2005/002782 WO2005077894A1 (en) | 2004-02-06 | 2005-02-01 | Modafinil compositions |
Publications (2)
Publication Number | Publication Date |
---|---|
CN1980888A CN1980888A (en) | 2007-06-13 |
CN1980888B true CN1980888B (en) | 2011-04-13 |
Family
ID=56290658
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN2005800041104A Expired - Fee Related CN1980888B (en) | 2004-02-06 | 2005-02-01 | Modafinil compositions |
Country Status (1)
Country | Link |
---|---|
CN (1) | CN1980888B (en) |
Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4177290A (en) * | 1977-03-31 | 1979-12-04 | Laboratoire L. Lafon | Acetamide derivatives |
US4927855A (en) * | 1986-01-31 | 1990-05-22 | Laboratoire L. Lafon | Levorotatory isomer of benzhydrylsulfinyl derivatives |
US20020043207A1 (en) * | 2000-07-27 | 2002-04-18 | Claude Singer | Oxidation method for preparing highly pure modafinil, crystalline forms of modafinil, and methods of preparing the crystalline forms |
-
2005
- 2005-02-01 CN CN2005800041104A patent/CN1980888B/en not_active Expired - Fee Related
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4177290A (en) * | 1977-03-31 | 1979-12-04 | Laboratoire L. Lafon | Acetamide derivatives |
US4927855A (en) * | 1986-01-31 | 1990-05-22 | Laboratoire L. Lafon | Levorotatory isomer of benzhydrylsulfinyl derivatives |
US20020043207A1 (en) * | 2000-07-27 | 2002-04-18 | Claude Singer | Oxidation method for preparing highly pure modafinil, crystalline forms of modafinil, and methods of preparing the crystalline forms |
Also Published As
Publication number | Publication date |
---|---|
CN1980888A (en) | 2007-06-13 |
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CI01 | Correction of invention patent gazette |
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Correction item: Priority Correct: 60/579,176 20040612 US False: Missing an earlier application data Number: 15 Page: The title page Volume: 27 |
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