CN1919167A - Titration control device for making large dropping pills - Google Patents
Titration control device for making large dropping pills Download PDFInfo
- Publication number
- CN1919167A CN1919167A CN 200510095928 CN200510095928A CN1919167A CN 1919167 A CN1919167 A CN 1919167A CN 200510095928 CN200510095928 CN 200510095928 CN 200510095928 A CN200510095928 A CN 200510095928A CN 1919167 A CN1919167 A CN 1919167A
- Authority
- CN
- China
- Prior art keywords
- dripping
- control device
- manufacturing large
- pillar according
- compressed air
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000006187 pill Substances 0.000 title claims abstract description 14
- 238000004448 titration Methods 0.000 title abstract 2
- 239000007788 liquid Substances 0.000 claims abstract description 20
- 238000001816 cooling Methods 0.000 claims abstract description 9
- 230000001105 regulatory effect Effects 0.000 claims abstract description 6
- 239000002826 coolant Substances 0.000 claims abstract description 5
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 15
- 238000004519 manufacturing process Methods 0.000 claims description 14
- 238000010438 heat treatment Methods 0.000 claims description 2
- 230000001276 controlling effect Effects 0.000 claims 1
- 239000003814 drug Substances 0.000 abstract description 5
- 230000005540 biological transmission Effects 0.000 abstract 1
- 238000000465 moulding Methods 0.000 description 4
- 238000005516 engineering process Methods 0.000 description 2
- 230000006837 decompression Effects 0.000 description 1
- 238000006073 displacement reaction Methods 0.000 description 1
- 239000002552 dosage form Substances 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 238000001125 extrusion Methods 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 239000007962 solid dispersion Substances 0.000 description 1
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- Infusion, Injection, And Reservoir Apparatuses (AREA)
- Medical Preparation Storing Or Oral Administration Devices (AREA)
Abstract
A titration control device for preparing big pills with more than 70 mg of pill weight comprises eight parts, namely a gas transmission pipe (1), a pressure regulating meter (2), a dropping liquid tank (3), a transfusion switch (4), a compressed air pressure and frequency regulator (5), a pneumatic control valve (6), a dripper (7) and a cooling column (8). The pneumatic pulse output from the compressed air pressure and frequency regulator acts on the pneumatic control valve, the dripper valve is switched according to the preset frequency, the flow of the liquid medicine output from the dripper tank is accurately controlled, the liquid medicine is dripped into the high-viscosity cooling agent of the cooling column and naturally contracted into pills by surface tension, and the large dropping pills which have the pill weight difference of more than 70 mg to 300 mg and are smoothly formed and meet the requirements of pharmacopoeia can be obtained.
Description
Affiliated technical field
The present invention is a kind of dripping control device that ball weighs the large dripping pillar more than 70 milligrams of manufacturing, and belongs to medical mechanical field.
Background technology
Drop pill is the classical dosage form of solid dispersion technology, has to absorb soon, and advantages such as bioavailability height are the developing direction of modern Chinese medicine.But, because existing drop pill machine can only be produced the following drop pill of 100mg mostly, dose is significantly increased, the patient has been brought inconvenience.Therefore, the above large dripping pillar production equipment of the heavy 70mg of ball includes the primary study development track in.The mold cools down of employing molding mode, plunger displacement pump extrusion way and large aperture water dropper pressure controling mode are arranged therebetween, but because of complex structure, the cost height, the product ball is heavy uneven, and molding is not round, all fails to satisfy user's needs, the production of can't finalizing the design.
Summary of the invention
The present invention is existing big, in, on the basis of small-sized drop pill machine, set up dripping control device, by adjustable decompression gas circuit, air control unit, compressed air pressure and frequency regulator that vacuum control loop and programmable timing circuit are formed, accurately drip system by the Hysteresis for Pneumatic Control Valves water dropper that connects in the dropping liquid tank bottom, drop pill is increased to about 70-300mg below the heavy 70mg of present ball, and the ball method of double differences is different little, the molding slyness, can reach country's " pharmacopeia " standard, expanded the drop pill production field greatly, positive impetus has been played in the development of modern Chinese medicine.
The large dripping pillar dripping control device is made up of appendix, voltage regulating meter, dropping liquid tank, transfuse switch, compressed air pressure and frequency regulator, pneumatic control valve, water dropper and cooling column eight parts.
Pneumatic control valve is by receiving from the air pulsing of compressed air pressure and frequency regulator output, by predefined frequency switching water dropper valve, control is from the flow of the medicinal liquid of dropping liquid tank output, and medicinal liquid splashes into and relies on surface tension to shrink molding naturally in the cooling column high-viscosity coolant.
A dripping control device can be controlled a water dropper, also can control several water droppers.
Temperature heating regulation and control will be arranged at cooling column top.Can be fixed, a plurality of water droppers drip system; Also can rotate, a water dropper drips system fast.
Figure of description
Among the figure 1, appendix 2, voltage regulating meter 3, dropping liquid tank 4, transfuse switch 5, compressed air pressure and frequency regulator 6, pneumatic control valve 7, water dropper 8, cooling column
The specific embodiment
Medicinal liquid is heat tracing in dropping liquid tank (3), opens transfuse switch (4) messenger drug liquid stream and goes into water dropper (7); Start compressed air pressure and frequency regulator (5), by the switch of appendix (1) control pneumatic control valve (6), medicinal liquid oozes in the coolant that falls into cooling column (8) by the frequency of setting, and relies on surface tension to be shrunk to ball naturally in liquid coolant.
Claims (9)
1, a kind of dripping control device of manufacturing large dripping pillar is characterized in that: be made up of appendix, voltage regulating meter, dropping liquid tank, transfuse switch, compressed air pressure and frequency regulator, pneumatic control valve, water dropper and cooling column eight parts.
2, a kind of dripping control device of manufacturing large dripping pillar according to claim 1, it is characterized in that: pneumatic control valve and water dropper link together.
3, a kind of dripping control device of manufacturing large dripping pillar according to claim 1, it is characterized in that: pneumatic control valve is connected with frequency regulator with compressed air pressure by appendix, and open and close with the pressure that sets, frequency, control the flow of medicinal liquid thus, guarantee the system of quantitatively dripping of medicinal liquid.
4, a kind of dripping control device of manufacturing large dripping pillar according to claim 1, it is characterized in that: the upper end and the dropping liquid tank of its device join, and by voltage regulating meter input compressed air, keep the isostasy in the dropping liquid tank, can be stable infuse to water dropper.
5, a kind of dripping control device of manufacturing large dripping pillar according to claim 1 is characterized in that: the dropping liquid tank of its connection has the function of heating and attemperation.
6, a kind of dripping control device of manufacturing large dripping pillar according to claim 1 is characterized in that: it receives drop pill postcooling post top and wants independent regulating and controlling temperature, makes temperature be higher than the stage casing and the hypomere of coolant.
7, a kind of dripping control device of manufacturing large dripping pillar according to claim 1 is characterized in that: a dripping control device can be controlled a water dropper, also can control some water droppers.
8, a kind of dripping control device of manufacturing large dripping pillar according to claim 1, it is characterized in that: cooling column can be fixed, also can rotate.
9, a kind of dripping control device of manufacturing large dripping pillar according to claim 1 is characterized in that: can produce more than 70 milligrams to about 300 milligrams large dripping pillar, also can produce the little drop pill below 70 milligrams.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN 200510095928 CN1919167A (en) | 2005-08-23 | 2005-08-23 | Titration control device for making large dropping pills |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN 200510095928 CN1919167A (en) | 2005-08-23 | 2005-08-23 | Titration control device for making large dropping pills |
Publications (1)
Publication Number | Publication Date |
---|---|
CN1919167A true CN1919167A (en) | 2007-02-28 |
Family
ID=37777108
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN 200510095928 Pending CN1919167A (en) | 2005-08-23 | 2005-08-23 | Titration control device for making large dropping pills |
Country Status (1)
Country | Link |
---|---|
CN (1) | CN1919167A (en) |
-
2005
- 2005-08-23 CN CN 200510095928 patent/CN1919167A/en active Pending
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Legal Events
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C06 | Publication | ||
PB01 | Publication | ||
C10 | Entry into substantive examination | ||
SE01 | Entry into force of request for substantive examination | ||
C12 | Rejection of a patent application after its publication | ||
RJ01 | Rejection of invention patent application after publication |
Application publication date: 20070228 |