CN1895596A

CN1895596A - Chinese medicine for treating diabetes and its preparation

Info

Publication number: CN1895596A
Application number: CNA2006100361325A
Authority: CN
Inventors: 江界
Original assignee: Individual
Current assignee: Individual
Priority date: 2006-06-29
Filing date: 2006-06-29
Publication date: 2007-01-17
Anticipated expiration: 2026-06-29
Also published as: CN100475252C

Abstract

A Chinese patent medicine composed of pills and decoction for treating diabetes is prepared from 22 Chinese-medicinal materials including astragalus root, white ginseng, rehmannia root, yam, etc. Its preparing process is also disclosed.

Description

Chinese patent medicine of treatment diabetes and preparation method thereof

Technical field

The invention belongs to the manufacture method of Chinese patent medicine, specifically is the Chinese patent medicine at diabetics.

Background technology

Diabetes are with polydipsia, polyphagia, polyuria, and health is become thin or urinated the pleasantly sweet disease of feature that is.Gu also claims " urinating sweet disease ".Disappearing on drinking water copiously being, disappear in mostly being with food, is diabetes due to kidney-deficiency with the frequent micturition.Doctor trained in Western medicine claims it is that sugar, fat, protein metabolism disorder absolute by insulin or that relative deficiency causes are main systemic disease.The disease feature is sugar to occur in the too high and urine of blood glucose.

One, the diabetes cause of disease and pathogenesis

The cause of disease: mainly be owing to natural endowment deficiency, intemperance of taking food, disorder of emotion, labor are desired excessively.Cause lung, stomach, kidney scorching, YIN fluid deficiency, dryness-heat being excessive in the interior and form.The natural endowment deficiency, the five internal organs weakness, especially kidney are plain empty, and store essential substances is not solid, and damage of essence liquid exhausts, and sends out to quenching one's thirst; Eating and drinking without temperance, long-term surfeit delicious food, the pure wine savoury makes the transporting and transforming function of the spleen and stomach dereliction of duty, accumulates in the long-pending heat, and fiery dry consumption Tianjin is sent out to quenching one's thirst; Disorder of emotion, excessively direct stimulation, so that mechanism of qi pent-up, and then fire-transformation, cloudy Tianjin of vehement bright lung, stomach, kidney and sending out to quenching one's thirst; Labor is desired excessively, and intemperate sexual intercourse, excessive, the cloudy essence of loss of impairment caused by overstrain cause YIN fluid being insufficient, and the deficiency of YIN is hyperactivity of fire then, on steam the lung stomach, send out to quenching one's thirst to suffering from a deficiency of the kidney stomach-heat due to lung-dryness eventually.

Pathogenesis: Pathogenesis of Diabetes mainly is: YIN fluid deficiency, dryness-heat being excessive in the interior and be this with the deficiency of YIN scorchingly are mark.The specimen reciprocal causation, cloudy more empty, scorching more Sheng.Scorching more Sheng, cloudy more empty.The internal organs of pathological changes relate to the five internal organs, but mainly at lung stomach kidney, especially with kidney for.Between the lung stomach kidney, often influence each other again.As the dryness of the lung deficiency of YIN, body fluid loses in compress, and then stomach loses and makes moist, and kidney loses and nourishes.The inclined to one side Sheng of the gastric heat lung Tianjin of can burning, the consume kidney yin.Deficiency of kidney yin, cloudy smart source dries up and exhausts, and hyperactivity of fire caused by deficiency of YIN also can be gone up the lung stomach that burns, and eventually to the dryness of the lung, gastric heat, suffers from a deficiency of the kidney usually existence simultaneously.Polydipsia, polyphagia, polyuria are mutually and see.

Quench one's thirst and with the passing of time do not heal, deficiency of YIN affecting YANG can cause deficiency of both QI and YIN, or deficiency in both YIN and YANG.Also can involve the five internal organs, cause the essence and blood exhaustion, accumulate in scorching, the moon exhausts sun and declines, and concurrent multiple double disease, i.e. diabetic complication.

Two, determination of treatment based on pathogenesis obtained through differentiation of symptoms and signs

At first will distinguish type according to the symptom of disease, doctor trained in Western medicine thinks that this sick generation is the result of pancreas degenerative.The Chinese traditional treatment primary disease is wanted the due to illness sick position of machine of differential diagnosis of diseases.Although usually polydipsia, polyphagia, polyuria occur simultaneously, the comparatively outstanding person of polydipsia is called and disappears, on disappear based on the dryness of the lung, see lung dryness of the stomach heat or dryness of the lung deficiency of the kidney more; Disappear during the comparatively outstanding person of polyphagia is called, in disappear with the gastric heat master, see gastrointestine dryness heat lung Tianjin deficiency or gastric heat deficiency of the kidney more; The comparatively outstanding person of polyuria is called diabetes due to kidney-deficiency, and diabetes due to kidney-deficiency is seen damage of kidney-YIN or kidney insufficiency to suffer from a deficiency of the kidney more.How the less important more first substantially disease of specimen primary and secondary of distinguishing is based on scorching, and the course of disease is than elder's deficiency of YIN and scorching cross-reference, and disease is for a long time based on the deficiency of YIN or deficiency in both YIN and YANG.Primary disease is mainly in more than the middle age in addition, and the middle-older patient complication of holding concurrently is more, and adolescent patient is rare, but adolescent patient has the state of an illness critical." face card guide " day: " three types of diabetes one card, though the branch of upper, middle and lower is arranged, hyperactivity of YANG due to deficiency of YIN more in fact,, Tianjin dry up hot sparrow hawk and with." scape high mountain institute cloud again: " fruit be excess-fire person, but removes its fire, and then body fluid is spontaneous, exhausts from only and disappear." for this reason, the treatment diabetes must be taked the method for heat clearing away Yin-nourishing and body fluid promoting.

In clinical practice, the common dark tongue quality of diabetics, tongue with petechiae or ecchymosis, sublingual vein be angry blood stasis sign such as opens.Originally the sick position that the disease of quenching one's thirst produces is at spleen (pancreas), Li Shizhen (1518-1593 A.D.) book day: " spleen pertaining to the earth is the mother of all things on earth, and main management is defended ..., master of spleen is sick, and all damp-edema are bloated ...." cause of disease of quenching one's thirst the above, mechanism of qi pent-up (irritability), intemperance of taking food, cause in insufficiency of the spleen resulting in production of dampness, damp heat-transformation, the pyretic toxicity accumulate, qi depression to blood stasis with the passing of time, expectorant gel knot is not changed.Pathological changes relates to the five internal organs, and scorching, hyperactivity of YANG due to deficiency of YIN appears in main lung stomach kidney.Cure the disease and to ask it at the position of generation.Heresy is not dispelled, is just how answered.Dispeling the filthy and spleen reinforcing spleen invigorating of the damp and hot evil poison of pancreas is to cure the key that diabetes be can not ignore.So I treat diabetes and adopt: with organic conception, the dialectical three major types type of dividing into; Treating both the principal and the secondary aspects of a disease at the same time, reinforcement and elimination in combination.With benefiting qi and nourishing yin, promote the production of body fluid and moisturize, same heat-clearing and toxic substances removing, the blood circulation promoting and blood stasis dispelling dampness removing turbid basic principle that is integrated as of dispelling.And blood circulation promoting and blood stasis dispelling, detoxifcation is dispelled and is turbidly run through treatment all the time.Deficiency of YIN affecting YANG person is in conjunction with tonifying both YIN and YANG.Complication person at the state of an illness in time in conjunction with employing, pathogenic fire purging, detoxify, invigorate blood circulation, method such as YANG invigorating arresting seminal emission executes simultaneously and controls.

The diabetes criterion of cure: 1, transference cure more than three, body constitution is recovered; 2, doctor trained in Western medicine check, (urine examination) on an empty stomach; Blood glucose 7.2 mMs/liter below; Glucose in urine (±), take a turn for the better: symptom disappears substantially more than three; 3, hematuria sugar all has decline, and more stable.

Summary of the invention

Composition of the present invention consists of:

The Radix Astragali 15～30 grams, Radix Ginseng's 5 grams, the Rhizoma Anemarrhenae 10 grams, Gypsum Fibrosum 15～30 grams, Radix Trichosanthis 15～30 grams, restrain Radix Ophiopogonis 15～30, Radix Panacis Quinquefolii 15～30 grams, the Radix Rehmanniae 15～30 grams, Radix Rehmanniae Preparata 15～30 grams, Rhizoma Dioscoreae 15～50 grams, Radix Scrophulariae 15～30 grams, Rhizoma Atractylodis 10～20 grams, Radix Salviae Miltiorrhizae 15～30 grams, Radix Puerariae 10～20 grams, Rhizoma Smilacis Chinensis 50～100 grams, 1～2 of Pancreas Sus domestica, the Radix Polygoni Multiflori 15～30 grams, Rhizoma Polygonati 15～30 grams, Herba Taxilli 20～30 grams, Concha Ostreae 30 grams, Radix Scutellariae 10～20 grams, Fructus Tribuli 15～30 grams.

Preparation method of the present invention is:

1, in the prescription: Radix Panacis Quinquefolii, Radix Ophiopogonis, the Radix Rehmanniae, Radix Rehmanniae Preparata, Rhizoma Dioscoreae.Making overall process avoids and use ironware, need 36 hours immersion Chinese liquor, saline; Charcoal fire, new tile roasting pulverize add smart winter honey white silk at last and make pill, and every ball weighs 9 grams.This ball name day: benefiting qi and nourishing yin tonify deficiency ball.

2, the fried patent medicine slurry of surplus medicine in the side.Way: coarse grain is dried in the Pancreas Sus domestica section, closes Rhizoma Smilacis Chinensis and, fries in shallow oil two times after 1 hour with the clear spring water logging bubble that contains various trace elements, 3 hours, gets dope; All the other medicines close and soak same clear spring water and fry in shallow oil after 1 hour and closed for two times 1.30 hours, press dry medicinal residues, get dense medicinal liquid (Radix Ginseng will fry in shallow oil the back taking liquid in addition), fry in shallow oil into medicinal liquid for three kinds and are mixed, and concentrate the patent medicine slurry, and it is fresh-keeping to bottle.This medicine slurry is named and is medicine slurry of blood sugar lowering.Has supplementing QI and nourishing YIN, spleen invigorating, spleen reinforcing, lung moistening nourishing kidney, blood circulation promoting and blood stasis dispelling, removing pathogenic heat from blood and toxic substance from the body, the dampness removing turbid effect of dispelling.

Effect of the present invention is:

Instructions of taking is a pill: respectively obeyed 1～2 ball in 1 hour after morning every day, the supper, and warm water delivery service, every day early respectively obeyed 50ml, warm boiled water on an empty stomach and before sleeping evening by the medicine slurry.15 days was 1 course of treatment.

We can use the glycosuria patient of non-dependence insulinize for the special side of treatment diabetes.Especially the course of disease is longer, and the deficiency of YIN is scorching, scorchingly goes into blood; Blood stasis due to qi deficiency; The deficiency of both QI and YIN person.And concurrent multiple angiopathy person is more suitable, as concurrent mashed foot (vasculitis) hyperlipemia, vascular hypertension, coronary heart disease, cerebrovascular accident (apoplexy) etc.

The pathogenesis of diabetes is mark with scorching, and the deficiency of YIN is this.Though we are divided into pill and slurry system, close and be usefulness, treating both the principal and the secondary aspects of a disease at the same time, reinforcement and elimination in combination, more outstanding strengthening the body resistance is so curative effect is apparent.Cure 1～6 course of treatment.I develop this product medicine so far, and clinical 312 examples are cured 233 examples, account for 80%.Blood glucose, glucose in urine are normal, and body constitution is recovered.

Model case: Chen, male, 48 years old, diagnosis and treatment in July, 2004 were suffered from diabetes 12 years, and right crus of diaphragm dish junk, the rotten bone of meat reveal year surplus (vasculitis) can not walk with descending, and it is weak to become thin, the wound liquid of suppurating, pain.Pale tongue is dark, and ecchymosis is arranged, and sublingual vein is angry opens stringy and thready pulse.Local examination in hospital report, glucose in urine (++ ++), 190 milligrams of % of blood glucose, through obeying the finished medicines that we develop, pill and slurry agent were accused more in 42 days, and glucose in urine, blood glucose are normal, mashed foot granulation promoting healing.Visit after 1 year, do not have recurrence.

The specific embodiment

Embodiment one:

In clinical practice, to the diabetes obstinate, symptom: frequent micturition is muddy as cream, very then drinks and lets out one, darkish complexion, helix is withered, soreness of the waist and knees, dry pharynx dryness of the tongue, the cold physique fear is cold, the sexual impotence erectile problem, pale tongue with white fur, the deficiency in both YIN and YANG of deep,thready and forceless pulse etc. and the full diabetics that relies on insulinize, with special side for square substantially, increase SIZI 15～30 grams, Cornu Cervi Degelatinatum 20～30 grams, Fructus Rosae Laevigatae 20～30 grams, Semen Euryales 15～30 grams, the Radix Paeoniae Alba 15～30 grams, Colla Corii Asini, each 10 gram (melt is converted when receiving slurry) of Colla Plastri Testudinis, Fructus Rubi 10～15 grams.

Make: identical with special side's manufacture method.Originally making that medicine slurry names is No. two medicines slurries of blood sugar lowering.

Instructions about how to take medicine: pill every day early, respectively obeyed 2～3 balls, warm water delivery service after the supper in 1 hour.Every day early respectively obeyed 50ml on an empty stomach and before sleeping evening by the medicine slurry, warm boiled water, and 15 days was 1 course of treatment.

Effect: nourishing liver and kidney, nourshing Yin and drynsessmoistening prescription, the spleen invigorating spleen reinforcing, activating blood, resolving stasis, dispelling is turbid.Cure 2～6 courses of treatment.

Cure mainly: diabetes, the course of disease is permanent, deficiency in both YIN and YANG and complete in relying on insulinize person, concurrent sexual impotence, edema, night blindness, diseases such as deafness.

Embodiment two:

In treatment diabetes process, another kind of symptom, excessive thirst polydipsia, rapid digestion of food is apt to flesh, urinary micturition, urine colour mixture Huang, health is gradually thin, red tongue, dry, rough and yellow fur, slippery and rapid pulse belongs to hyperactivity of fire caused by deficiency of YIN person deducts the Radix Polygoni Multiflori, Rhizoma Polygonati, the Radix Astragali, Rhizoma Atractylodis with special side, adds Cornu Cervi Degelatinatum 10～30 grams, Flos Sophorae 10～30 grams, Radix Sophorae Flavescentis 10～15 grams, Poria 10～20 grams, Fructus Rubi 10～20 grams, Rhizoma Coptidis 10～15 grams.

Make: identical with special side's manufacture method.It is No. three medicines slurries of blood sugar lowering that this medicine makes that medicine slurry names.

Instructions about how to take medicine: pill every day early, respectively obeyed 1 ball, warm water delivery service after the supper in 1 hour.Every day early respectively obeyed 50ml, warm boiled water on an empty stomach and before sleeping evening by the medicine slurry.15 days was 1 course of treatment.

Effect: nourishing YIN to lower pathogenic fire, reinforcing spleen and kidney, blood circulation promoting and blood stasis dispelling turbidity removal.Cure 1～4 course of treatment.

Claims

1, Chinese patent medicine of treatment diabetes and preparation method thereof is characterized in that composition consists of: the Radix Astragali 15～30 grams, Radix Ginseng's 5 grams, the Rhizoma Anemarrhenae 10 grams, Gypsum Fibrosum 15～30 grams, Radix Trichosanthis 15～30 grams, restrain Radix Ophiopogonis 15～30, Radix Panacis Quinquefolii 15～30 grams, the Radix Rehmanniae 15～30 grams, Radix Rehmanniae Preparata 15～30 grams, Rhizoma Dioscoreae 15～50 grams, Radix Scrophulariae 15～30 grams, Rhizoma Atractylodis 10～20 grams, Radix Salviae Miltiorrhizae 15～30 grams, Radix Puerariae 10～20 grams, Rhizoma Smilacis Chinensis 50～100 grams, 1～2 of Pancreas Sus domestica, the Radix Polygoni Multiflori 15～30 grams, Rhizoma Polygonati 15～30 grams, Herba Taxilli 20～30 grams, Concha Ostreae 30 grams, Radix Scutellariae 10～20 grams, Fructus Tribuli 15～30 grams; Preparation method is:

(1), in the prescription: Radix Panacis Quinquefolii, Radix Ophiopogonis, the Radix Rehmanniae, Radix Rehmanniae Preparata, Rhizoma Dioscoreae, make overall process and avoid and use ironware, need 36 hours immersion Chinese liquor, saline; Charcoal fire, new tile roasting pulverize add smart winter honey white silk at last and make pill, and every ball weighs 9 grams;

(2), the fried patent medicine of surplus medicine is starched way in the side: coarse grain is dried in the Pancreas Sus domestica section, closes Rhizoma Smilacis Chinensis and, fries in shallow oil two times after 1 hour with the clear spring water logging bubble that contains various trace elements, 3 hours, gets dope; All the other medicines close and soak same clear spring water and fry in shallow oil after 1 hour and closed for two times 1.30 hours, press dry medicinal residues, get dense medicinal liquid (Radix Ginseng will fry in shallow oil the back taking liquid in addition), fry in shallow oil into medicinal liquid for three kinds and are mixed, and concentrate the patent medicine slurry, and it is fresh-keeping to bottle.

2, Chinese patent medicine of treatment diabetes according to claim 1 and preparation method thereof, it is characterized in that with above-mentioned special side for square substantially, composition consists of increases SIZI 15～30 grams, Cornu Cervi Degelatinatum 20～30 grams, Fructus Rosae Laevigatae 20～30 grams, Semen Euryales 15～30 grams, the Radix Paeoniae Alba 15～30 grams, Colla Corii Asini, each 10 gram (melt is converted when receiving slurry) of Colla Plastri Testudinis, Fructus Rubi 10～15 grams.

3, Chinese patent medicine of treatment diabetes according to claim 1 and preparation method thereof, it is characterized in that deducting the Radix Polygoni Multiflori, Rhizoma Polygonati, the Radix Astragali, Rhizoma Atractylodis with above-mentioned special side, add Cornu Cervi Degelatinatum 10～30 grams, Flos Sophorae 10～30 grams, Radix Sophorae Flavescentis 10～15 grams, Poria 10～20 grams, Fructus Rubi 10～20 grams, Rhizoma Coptidis 10～15 grams.