CN1887278A - Slow released doxazosin mesilate capsule and its prepn process - Google Patents
Slow released doxazosin mesilate capsule and its prepn process Download PDFInfo
- Publication number
- CN1887278A CN1887278A CNA2006100455568A CN200610045556A CN1887278A CN 1887278 A CN1887278 A CN 1887278A CN A2006100455568 A CNA2006100455568 A CN A2006100455568A CN 200610045556 A CN200610045556 A CN 200610045556A CN 1887278 A CN1887278 A CN 1887278A
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- CN
- China
- Prior art keywords
- capsule
- slow
- doxazosin
- release
- carclura
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Description
Time (h) | 0.083 | 0.167 | 0.25 | 0.5 | 0.75 | 1 |
Dissolution (%) | 37 | 75 | 94 | 99 | 100 | 98 |
Time (h) | 2 | 4 | 6 | 8 | 10 | 12 | 15 | 24 |
Dissolution (%) | 6 | 32 | 41 | 56 | 77 | 93 | 103 | 101 |
Time (h) | 4 | 6 | 8 | 12 | 24 | ||
| Embodiment | 1 | 25 | 38 | 63 | 94 | 99 |
| 12 | 31 | 52 | 79 | 91 | ||
| 19 | 35 | 59 | 92 | 97 |
Claims (6)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CNB2006100455568A CN100396282C (en) | 2006-07-25 | 2006-07-25 | Slow released doxazosin mesilate capsule and its prepn process |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CNB2006100455568A CN100396282C (en) | 2006-07-25 | 2006-07-25 | Slow released doxazosin mesilate capsule and its prepn process |
Publications (2)
Publication Number | Publication Date |
---|---|
CN1887278A true CN1887278A (en) | 2007-01-03 |
CN100396282C CN100396282C (en) | 2008-06-25 |
Family
ID=37576557
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CNB2006100455568A Expired - Fee Related CN100396282C (en) | 2006-07-25 | 2006-07-25 | Slow released doxazosin mesilate capsule and its prepn process |
Country Status (1)
Country | Link |
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CN (1) | CN100396282C (en) |
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN102816154A (en) * | 2012-09-10 | 2012-12-12 | 刘庆彬 | Amorphous state monohydrate (-)-doxazosin mesylate and preparation method and application thereof |
CN103705490A (en) * | 2013-10-31 | 2014-04-09 | 蚌埠丰原医药科技发展有限公司 | Slow-release preparation of ornithine aspartate and preparation process thereof |
CN104983717A (en) * | 2015-06-04 | 2015-10-21 | 湖北生物医药产业技术研究院有限公司 | Sodium prasterone sulfate sustained-release capsule and preparation method thereof |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5710295A (en) * | 1995-06-06 | 1998-01-20 | Hampshire Chemical Corp. | Preparation of alkali metal acyl amino acids |
GB9523752D0 (en) * | 1995-11-21 | 1996-01-24 | Pfizer Ltd | Pharmaceutical formulations |
CN1083451C (en) * | 1999-08-20 | 2002-04-24 | 广东康美药业股份有限公司 | Process for synthesizing doxazosin mesylate |
CN1194694C (en) * | 2002-08-26 | 2005-03-30 | 鲁南制药股份有限公司 | Slow-releasing maclobemide capsule |
-
2006
- 2006-07-25 CN CNB2006100455568A patent/CN100396282C/en not_active Expired - Fee Related
Cited By (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN102816154A (en) * | 2012-09-10 | 2012-12-12 | 刘庆彬 | Amorphous state monohydrate (-)-doxazosin mesylate and preparation method and application thereof |
CN102816154B (en) * | 2012-09-10 | 2015-08-19 | 刘庆彬 | A kind of non-crystalline state one hydration (-)-doxazosin mesylate, preparation method and application thereof |
CN103705490A (en) * | 2013-10-31 | 2014-04-09 | 蚌埠丰原医药科技发展有限公司 | Slow-release preparation of ornithine aspartate and preparation process thereof |
CN103705490B (en) * | 2013-10-31 | 2016-08-17 | 蚌埠丰原医药科技发展有限公司 | The slow releasing preparation of a kind of aspartic acid ornithine and preparation technology thereof |
CN104983717A (en) * | 2015-06-04 | 2015-10-21 | 湖北生物医药产业技术研究院有限公司 | Sodium prasterone sulfate sustained-release capsule and preparation method thereof |
Also Published As
Publication number | Publication date |
---|---|
CN100396282C (en) | 2008-06-25 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
C06 | Publication | ||
PB01 | Publication | ||
C10 | Entry into substantive examination | ||
SE01 | Entry into force of request for substantive examination | ||
C14 | Grant of patent or utility model | ||
GR01 | Patent grant | ||
C56 | Change in the name or address of the patentee | ||
CP02 | Change in the address of a patent holder |
Address after: Xinluo Avenue high tech Zone of Ji'nan City, Shandong province 250101 No. 989 Shandong Academy of Pharmaceutical Sciences Room 401 Patentee after: Medicine Industry Inst., Shandong Prov. Address before: 250100 Shandong Pharmaceutical Industry Research Institute, 52 Da Bei Road, Shandong, Ji'nan Patentee before: Medicine Industry Inst., Shandong Prov. |
|
EE01 | Entry into force of recordation of patent licensing contract |
Assignee: Zibo Shandong mountain Pharmaceutical Co., Ltd. Assignor: Medicine Industry Inst., Shandong Prov. Contract record no.: 2011370000035 Denomination of invention: Slow released doxazosin mesilate capsule and its prepn process Granted publication date: 20080625 License type: Exclusive License Open date: 20070103 Record date: 20110314 |
|
CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20080625 Termination date: 20150725 |
|
EXPY | Termination of patent right or utility model |