CN1886492A - High alcohol content gel-like and foaming compositions - Google Patents

High alcohol content gel-like and foaming compositions Download PDF

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Publication number
CN1886492A
CN1886492A CN 200480035318 CN200480035318A CN1886492A CN 1886492 A CN1886492 A CN 1886492A CN 200480035318 CN200480035318 CN 200480035318 CN 200480035318 A CN200480035318 A CN 200480035318A CN 1886492 A CN1886492 A CN 1886492A
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composition
alcohol
weight
consumption
pure
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布鲁斯·迈克尔·科依维斯托
马里亚·特蕾莎·费尔南德斯德卡斯特罗
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DEB Worldwide Healthcare Inc
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DEB Worldwide Healthcare Inc
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Abstract

This invention relates to a 'high lower alcohol content' (>40% v/v of a C<SUB>1-4 </SUB>alcohol) liquid composition able to be either dispensed as a stable foam with the use of non-propellant foam dispensing devices from non-pressurized containers or as an alcohol gel composition which does not use thickener and gelling agents that leave undesirable deposits or a sticky after-feel and that has a final viscosity less than 4,000 cps. The liquid compositions comprise an alcohol, C<SUB>1-4 </SUB>(>40% v/v), a fluorosurfactant of at least 0.001% by weight to prepare a foamable composition or from 0-2.0% to prepare a gel-like composition of a final viscosity less than 4,000 cps, 0-10% w/w of additional minor components added to obtain the desired performance (a foamable composition or a gel-like composition with a viscosity less than 4,000 cps), and the balance being purified water. The compositions may include emulsifier-emollients and mosturizers, secondary surfactants, foam stabilizers, fragrances, antimicrobial agents, other type of medicinal ingredients, and the like ingredients or additives or combinations thereof commonly added to alcohol gels or foams, aerosol compositions or to toiletries, cosmetics, pharmaceuticals and the like.

Description

Height contains the gel-form composition and the foaming composition of alcohol amount
Cross-reference to related applications
Present patent application relates to and requires the applying date is that September 29, application number in 2003 are 60/506,172 the U.S. Provisional Patent Application and the applying date are that July 28, application number in 2004 are 60/591, the right of priority of 601 U.S. Provisional Patent Application, the full content of these patents is introduced into this paper as a reference.
Technical field
The present invention relates to have high-load lower alcohol (C 1-4) composition, it can be gel-form composition or the solution that can provide as foam.Described described composition with the form of foam granting comprises fluorochemical surfactant and produce the stable pure foam that can be used for personal cleanliness or sterilisation purpose when with air mixed.Described gel-form composition can contain or not contain fluorochemical surfactant.
Background technology
Ethanol and/or Virahol composition that content is at least 60 volume % (about 52 weight %) are the antiseptic-germicides of knowing, and are therefore accepted to be used for sterilisation purpose widely.But because the intrinsiccharacteristic of alcohol, high product is good more more to realize its content, and the solution that the alcohol amount of containing is higher than 60 volume % is more preferably.
In order to cut the waste and to be convenient to described composition is coated on the whole desired zone, pure disinfectant solution is generally by thickening.Also known except jelling agent, can use paraffin or wax to realize the thickening of the solution of high density alcohol.United States Patent (USP) the 2nd, 054 has been described this lanolin that added in No. 989 to reduce its fusing point to the composition near body temperature.One of shortcoming of gel and this composition that comprises high density alcohol is if want to allow them not stay heavy-gravity sensation (although some are like this really) on hand after use, increase reusing this effect in back in the daytime, just must be at flush away thickening material before the pure antiseptic solution of use continuously.If be used for this product by preparation, the present invention can not stay this sensation, and does not need by flush away after repeated use yet.
Another kind of thickening height contains the method for solution of alcohol amount also at United States Patent (USP) the 6th, 090, and 395 and 6,623, instruction in No. 744, wherein these patents use emulsifying agents and tensio-active agent to be at least 4 as thickened systems to produce viscosity, the water alcohol lotion of 000cps.In addition, United States Patent (USP) the 4th, 956 discloses the stable emollient oil of being added of the nonionogenic tenside/emulsifying agent that uses polyethoxylated except that fatty alcohol for No. 170, although by add polymeric viscosifier prepare water alcohol skin mend wet/regulate antibacterial gel.Gel sanitizing composition of the present invention has and is lower than 4, the viscosity of 000cps and need not add polymeric viscosifier.
Generally speaking, height contains pure sterilized solution sterilization of measuring but is unclean.In order to make its sterilization and cleaning, the foam that needs are a lot, this makes skin feel satiny and not well, this for. be unacceptable for the rubbing alcohol.But, as United States Patent (USP) the 5th, 629, No. 006 described, by combination emulsifying agent, tensio-active agent with as the softener that gel or ointment use, successfully obtains the sterilised formula as the nonirritating high lower alcohol content of skin clean-out system.
Tensio-active agent except cleaning purpose because its wetting property waterborne compositions that can also be used for comprising one or more active substances is coated to the surface fast and equably.Use good wetting agent to improve the effective use of active substance in different compositions clearly, as United States Patent (USP) the 5th, 928, No. 993 described.Therefore, the composition of describing among the present invention comprises the interpolation tensio-active agent, specifically because of the known fluorochemical surfactant of its unparalleled wetting ability, described fluorochemical surfactant is surface-active in the lower alcohol as sterilizing agent and solvent system, even its consumption makes it also can be by being subjected to for the rubbing alcohol purpose, thereby cleaning, wetting and foam properties are provided for described composition.
Although the high disinfectant solution that contains the alcohol amount has the good disinfectant characteristic, it has pungent smell and generally is considered to cause xerosis cutis, and this shortcoming also is reduced to desirable level in the present invention.
Be higher than 40 volume % alcohol, use easily and the froth product of safety is better than traditional gel or ointment type composition product.Alcohol content itself has just constituted a kind of harm, and in many application, if it can not use the aerosol container of pressurization and with the granting of foamy form, just can reduce described harm.Plan to have uniform denseness, spreadability, cleaning capacity as the foam of skin antiseptic, and has comfortable sensation, promptly have the ability of breaking fast when exerting pressure, all these require all challenges of composition for high lower alcohol content.
United States Patent (USP) the 3rd, 962,150 have described the alcohol that the uses 15 weight % aqueous foam skin degerming composition as cosolvent, and it does not need the container that pressurizes or adds propelling agent to produce foam.
High containing can not form stable foam when alcohol is measured to the formation foamy reagent of Shi Yonging under the situation of not using other component when liquid phase has so far.In addition, it is believed that lower alcohol is defoamer rather than the reagent that promotes into bubble.At United States Patent (USP) the 3rd, 131, No. 153 described according to Klausner, is higher than 64% alcohol if use, and will obtain heterogeneous composition.Composition in this patent needs propelling agent to bubble and the foam that produced has limited stability.
Before the present invention, when needing in the product to be higher than the determining alcohol of 40 volume %, generally believe that this product will be liquid or gel, and foam if desired, so Chun concentration need reduce or will need to use propelling agent and compression system.
Astoundingly, contain in the pure volume production product at disclosed rare " can become to steep " height, gained foamy type is also dissimilar with the foam-type that expection from the aqueous solution obtains.The foam of gained is described as fast or the foam of inflation, break fast, has low or limited stability, and this foam can not continue generally will disappear in several seconds more than 1 minute.
Openly can make up fluorochemical surfactant and alcohol, produce " stable " foam by using the method that produces the foamy high-tension unit.United States Patent (USP) the 4th, 440, the foam that high stability pressurized foaming that comprises high lower alcohol content and forming method thereof is provided in No. 653 and uses this pressurization in petroleum industry wherein uses nonionogenic tenside or the non-ionic surfactant mixture that is selected from specific fluorochemical surfactant.Composition in this patent need use the gas system of pressurization to produce foam.
Although the various examples that have high lower alcohol content and can be used as the composition of foam granting have been described, but for the object of the invention, described foam characteristic is not required result, because they are quick disruptive, low stability and can only produce foam by propelling agent and aerosol container, as at United States Patent (USP) the 5th, 906, described in 808, this patent disclosure a kind of combination of using emulsifying wax NF and stearyl alcohol and Cetyl Alcohol, the perhaps product of other wax combination, these materials combine the foam performance that has improved described composition with lactic acid spermaceti ester, produce 0.8% chlorhexidine glucose acid alcohol product.
The United States Patent (USP) of authorizing Lins discloses for the 5th, 167, No. 950 and has a kind ofly needed propelling agent and need not add the froth product of tensio-active agent as sanitising agent.Disclosed composition is based on using emulsifier system (aliphatic alcohol roh 16-22 carbon) and being used in combination thickening material (carbomer, hydroxypropylcellulose (klucel) etc.) in this patent.
The United States Patent (USP) of authorizing Lins discloses a kind of antibiotic aerosol mouse that height contains the alcohol amount that has for the 5th, 167, No. 950.This mousse comprises alcohol, water, polymerization jelling agent and comprises the surfactant system of C16-22 alcohol, aerosol propellants and nonionic polyethoxylated tensio-active agent.Although carried out some researchs up to now, but shown for foam how to react and be also knowing little about it of how forming, and look that surprisingly as if can not form the foamy prescription can produce best foam, and other produce the foamy prescription in the preparation always and in some non-aerosol foam sending traps (dispenser), can not well use at all.The characteristic of aqueous foam is different from pure foam.
There is worthless characteristic in the traditional method of using polymer viscosifier to form gel, and is similarly doing seldom aspect the formation emulsion form thickening gel.
The alcohol-based disinfectant prescription that can be used as gel or foam granting will be very favorable.In addition, find that concentration highly beneficial and preferably whipping agent is enough low, use the zone to such an extent as to use the product of described whipping agent after using, can be retained in, and do not need to wash off, because the amount of residual remnants is very little after the evaporation.Therefore, very advantageously provide such foam or gel product, the delivery apparatus that it can not bring offending sensation that is clamminess that known most commercial alcogel product makes us staying or obstruction to be used for providing foam and gel after usefulness.
Summary of the invention
The purpose of this invention is to provide the liquid composition that height contains the alcohol amount, it comprises tensio-active agent/sanitising agent and sterilizing agent/sanitising agent/solvents/carriers, and skin or hand for the user only cause very slight drying, and can provide with gel or foamy form from pressurization and non-pressurized system.
The invention provides the composition that is applied to required lip-deep gel easily or can contains the alcohol amount as the height of foam granting.In the various application that may use described composition, the present invention also provides antimicrobial alcohol foam and antimicrobial alcogel on the other hand.Described foaming composition is being stable when suitable sending trap (dispenser) is provided and is not needing to use the container of propelling agent and pressurization.Viscosity disclosed herein is lower than 4, the gel of 000cps does not use jelling agent or the thickening material that the typical case uses in commercial gel, therefore after one or many uses this gel, do not have the sensation that is clamminess after the common usefulness, and described gel can not stop up the sending trap of providing gel.
From following specification sheets of the present invention, it is obvious that these and other objects and advantage will become.All percentage compositions provided herein all are based on gross weight except as otherwise noted.
Therefore, the invention provides the following composition that is used for Personal hygiene.
Foaming composition (Foamable Composition)
The invention provides a kind of foaming composition, it comprises:
A) consumption is greater than the C of about 40 volume % of total composition amount 1-4Alcohol or its mixture;
B) consumption be at least total composition 0.001 weight % be used for wetting and the foaming effective fluorine-containing surfactants reagent; And
C) make total composition reach the water of the surplus of 100 weight %.
Of the present invention above-mentioned aspect in, the consumption of described effective fluorochemical surfactant be total composition weight about 0.001% to about 10.0%, this is acceptable on physiology, so can be used to personal care type product.
In the preferred embodiment of the invention, described fluorochemical surfactant can be an amphoteric tetrafluoroethylene acetoxyl group CAB: (CF 3CF 2(CF 2CF 2) nCH 2CH 2(OAc) CH 2N +(CH 3) 2CH 2COO -), n=2 to 4 in the formula; Nonionic fluorochemical surfactant with ethoxylation of following structure: RfCH 2CH 2O (CH 2CH 2O) xH, wherein Rf=F (CF 2CF 2) y, x=0 is to about 15, and y=1 is to about 7; Anion phosphate (phosphate) fluorochemical surfactant or their mixture that perhaps have following structure: (RfCH 2CH 2O) xP (O) (ONH 4) y, Rf=F (CF in the formula 2CF 2) z, x=1 or 2, y=2 or 1, and z=1 is to about 7; Perhaps their mixture.
In another aspect of the present invention, provide a kind of pure sanitizing composition, it comprises:
A) consumption is the ethanol of about 60 volume % to 70 volume % of total composition;
B) consumption is the physiologically acceptable fluorochemical surfactant of about 0.01 weight % of total composition to about 2.0 weight %;
C) consumption is about 0.01 to about 10.0 weight % at least a nonionogenic tenside that is selected from the polyethoxylated fatty alcohol;
D) suds-stabilizing agent; And
E) make total composition reach the water of the surplus of 100 weight %.
The present invention also provides a kind of pure sanitizing composition, and it comprises:
A) consumption is the ethanol of about 60 volume % to 70 volume % of total composition;
B) consumption is the physiologically acceptable fluorochemical surfactant of about 0.01 weight % of total composition to about 2.0 weight %;
C) at least 1% n-propyl alcohol;
D) comprise the suds-stabilizing agent of the butyl cellosolve of 2% 1,3 butylene glycol, about 0.001-3% at least;
E) the lipid layer toughener of alkyl glucoside and olein mixture (lipidlayer enhancer) for example; And
F) make total composition reach the water of the surplus of 100 weight %.
Gel-form composition
Of the present invention aspect this in, a kind of alcogel shape composition is provided, it comprises:
A) C 1-4Alcohol or its mixture, its consumption is greater than about 40 volume % of total composition;
B) at least a nonionogenic tenside, it is selected from following material: poly-(ethoxylation and/or propoxylation) alcohol, poly-(ethoxylation and/or propoxylation) ester, the derivative of poly-(ethoxylation and/or propoxylation) alcohol, the derivative of poly-(ethoxylation and/or propoxylation) ester, alkyl alcohol, alkenyl alcohol, the ester of polyhydroxy-alcohol, the ether of polyhydroxy-alcohol, the ester of the poly-alkoxylation derivative of polyhydroxy-alcohol, the ether of the poly-alkoxylation derivative of polyhydroxy-alcohol, sorbitan fatty(acid)ester, the poly-alkoxylation derivative of sorbitan fatty(acid)ester and their mixture, its consumption at about 0.10 weight % between about 5 weight %;
C) emulsifying agent, its consumption at about 0.10 weight % between about 3.0 weight %; And
D) water, its consumption are enough to form stable gel shape sanitizing composition.
Composition disclosed herein provides a large amount of and high widely sterilized product that contains the alcohol amount.According to the percentage composition of the alcohol that uses in the described composition and by changing the ratio of other component in the prescription, can obtain to have foam of different nature, thereby can produce fast the coarse grain (coarse) that shakeouts (flatten) or the foam of wetting (wet); Perhaps comprise Aphron and soft foam dried relatively and that have long froth stability; The dense foam of perhaps gelatinous butteriness (thickfoams).In addition, according to the content of alcohol, these compositions can yes or no disappear toxic.
Be surprised to find by changing the content of each composition, can obtain can not make the alcogel shape composition that hand is dry or can not stay the sensation that is clamminess after usefulness and can not stop up the gel sending trap, said composition has required denseness and shows and is lower than 4, the viscosity of 000cps.
Some compositions can prepare with two-step approach easily, can will be fit to load and transport by the first part of the less enriched material of not too danger and weight as described composition, thereby most alcohol can be added in later time and/or place.The described first part to 30 of heating has improved the permanent stability of described composition to 80 degrees centigrade (depending on concrete composition) before adding most of alcohol.Described heating can be carried out on the same day at the same position of preparation final composition, perhaps can will store or load and transport to other places as the enriched material of first part, and heat at once when mixing described first part or before adding most of alcohol.
Significantly, can be at concrete application and/or be improved to the gel that comprises required activeconstituents or foam and can not deviate from scope of the present invention with described embodiment adjustment.For this reason, may need to use different materials and/or one-tenth to assign to compensate described composition and/or the destruction of the froth stability that may be caused by described adjustment (is promptly introduced more compatible auxiliary or tensio-active agent of equal importance, regulate the percentage composition of compatible suds-stabilizing agent and/or the relative content of change emulsifying agent and/or alcohol or water), perhaps (promptly reduce the consumption of fluorochemical surfactant or increase the polyethoxye tensio-active agent to obtain required gel in order to the change that compensates required viscosity and foam characteristic, perhaps add emulsifying agent and/or increase or reduce alcohol and/or water).Can at length carry out the change of these and other in the scope of spirit of the present invention, the feature in appending claims, these all should give generalized and explain rather than restrictive understanding.
For instance, pure based composition and use thereof in packaging can comprise be no more than 10 weight % add other activeconstituents or additive or their combination in aerosol composition or toiletry (toiletries), makeup (cosmetics), medicine etc. usually to.The material that can add comprises that mixture, suspension agent, buffer reagent, conditioning agent, antioxidant, sterilant, the medicinal actives of lower alkane alcohol amide, short-chain diol and/or triol, alkyl glucoside, spices, pigment, additional softener, UV light absorber, solvent, emulsifying agent, suds-stabilizing agent or this stablizer of organic natural gum and colloid, higher fatty acid become to grade.
The invention provides a kind of composition, it comprises:
A) consumption is greater than the C of about 40 volume % of total composition amount 1-4Alcohol or its mixture;
B) at least a nonionogenic tenside between about 5 weight %, it is selected from following group consumption at about 0.10 weight %: poly-(ethoxylation and/or propoxylation) alcohol, poly-(ethoxylation and/or propoxylation) ester, the derivative of poly-(ethoxylation and/or propoxylation) alcohol, the derivative of poly-(ethoxylation and/or propoxylation) ester, alkyl alcohol, alkenyl alcohol, the ester of polyhydroxy-alcohol, the ether of polyhydroxy-alcohol, the ester of the poly-alkoxylation derivative of polyhydroxy-alcohol, the ether of the poly-alkoxylation derivative of polyhydroxy-alcohol, sorbitan fatty(acid)ester, the poly-alkoxylation derivative of sorbitan fatty(acid)ester and their mixture;
C) consumption is at the emulsifying agent of about 0.10 weight % between about 3.0 weight %; And
D) consumption is enough to form viscosity and is lower than 4, the water of the stable gel shape composition of 000cps.
To describe the present invention in conjunction with many specific embodiments, these embodiment just illustrate rather than are restrictive.Yet the present invention will prepare a large amount of products, and should understand the embodiment that can adopt other and also can make variation and can not deviate from scope of the present invention.
Embodiment
Definition
When broadly referring to keep or to improve moisture content, kindliness or repeated use, term used herein " softener " keeps or improves the material of the outward appearance of skin.
Term used herein " emulsifying agent " refer to for the formation that helps emulsion and stable and in two kinds of mixable liquid a small amount of tensio-active agent or other material that adds.
Phrase used herein " emulsified component " is the synonym of mentioned emulsifier.
Term used herein " emulsion " refers to the colloidal dispersion of a kind of liquid in another kind of liquid.
Term used herein " tensio-active agent " is the abbreviation of widely used " surface-active agents ", it is to owing to existing lyophily and lyophoby structural unit to be preferentially adsorbed on the descriptive general terms of material at the interface, and this absorption causes the change of system surfaces or interfacial property usually.
Term used herein " fluorochemical surfactant " refers to comprise can make composition cleaning, wetting and blistered fluoro surface-active agents.
Phrase used herein " suds-stabilizing agent " refers to increase foamy amount or the persistent additive that is produced by surfactant system.
Phrase used herein " gel-form composition " refers to that pure content is at least the water-alcohol solution of 40 volume % (hydroalcoholic solution), and it has greater than water but less than 4 the viscosity of 000cps by using emulsifying agent and tensio-active agent to be thickened to.
Term " sterilisation " used herein means to be eliminated or the minimizing harmful microorganism.
The invention provides can be with the high lower alcohol (C that has of gel or the granting of foamy form 1-4) composition of content.This foaming composition discharges stable foam when with air mixed, can be used for the personal cleanliness or be used for sterilisation purpose alcohol-group liquid solution thereby provide, described foam when pressurized (for example when the user rub hands or when being applied to the surface and going up) break.Described gelatinous composition discharges and can easily be coated on hand, but the liquid of the d spiss that can not drip.The described gelatinous composition that has 60 volume % alcohol at least provides in case the alcohol evaporation can not stay the effective disinfectant of the sensation that is clamminess after the usefulness, this sensation is common in the alcogel that uses thickening material commonly used in the past and jelling agent during one or many is used.Described gelatinous composition is not easy to stop up described sending trap as gel product commonly used.
The alcohol that uses among the present invention is the alcohol of rudimentary hydrocarbon chain, for example C 1-4Alcohol.Preferred alcohol is selected from ethanol, 2-propyl alcohol or n-propyl alcohol, ethanol most preferably, and this is accepted extensively as suitable sterilizing agent under suitable percentage composition by the health worker.The present invention's expection can be used the mixture of a kind of alcohol or two or more alcohol for gel or foamed products in composition.
Foaming composition
One of Main Achievements of the present invention is to produce to go up the composition of the pure content of attractive foam granting greater than 40 volume % as making up.Another important achievement be do not use under the situation that well known to a person skilled in the art typical jelling agent obtain not stop up sending trap or stay with after the alcogel of the sensation that is clamminess.
Fluorochemical surfactant is that design disclosed herein comes the key component in the blistered composition as main whipping agent.Fluorochemical surfactant has many useful properties, for example stays seldom residual, can work under the chemistry of harshness and thermal environment; They have unparalleled wetting ability etc.Different with traditional tensio-active agent, they show uncommon surface-active property in well known to a person skilled in the art organic solvent, and it is widely used in the application such as coating, oil field, material finish, cleaning, paint.
The fluorochemical surfactant that is applicable to these type of composition can include, but are not limited to be fluoridized and with fluoro ethoxylate, glyceryl ester, amine oxide, propargyl alcohol derivative, carboxylicesters, phosphoric acid ester, carbohydrate derivates, sulphonate, trimethyl-glycine, ester, polymeric amide, organosilicon and the hydrocarbon tensio-active agent of other component compatibility that is used for special formulation.
Preferred fluorochemical surfactant is tetrafluoroethylene acetoxyl group CAB (CF 3CF 2(CF 2CF 2) nCH 2CH 2(OAc) CH 2N +(CH 3) 2CH 2COO -), n=2-4 in the formula.But, it is believed that also and can use other fluorochemical surfactant, comprise as non-limiting example being used for the nonionic fluorochemical surfactant with ethoxylation of following structure of the present invention: RfCH 2CH 2O (CH 2CH 2O) xH, wherein Rf=F (CF 2CF 2) y, x=0 is to about 15, and y=1 is to about 7; Have the anion phosphate fluorochemical surfactant of following structure or their mixture: (RfCH 2CH 2O) xP (O) (ONH 4) y, Rf=F (CF in the formula 2CF 2) z, x=1 or 2, y=2 or 1, x+y=3, and z=1 is to about 7; Perhaps their mixture.
Has described characteristic although be surprised to find fluorochemical surfactant, but except as United States Patent (USP) the 4th, 440, the use nonionic fluorochemical surfactant of being instructed in No. 653 and the gas of pressurization are as outside the whipping agent, seldom have or do not have to contain the information that alcohol is measured high foamed products about producing with them, this patent is incorporated herein by reference.
In addition, even in order to obtain also can produce foamy under pressurizing vessel or the propelling agent and contain the high product of alcohol amount not using, need capillary value low as far as possible, so that promptly be enough to provide the described foam of generation required pressure by manual pump and mechanism.Therefore, the surface tension value that is lower than 20dynes/cm (25 ℃ of 0.01%DW) that these tensio-active agents can be realized makes it be applicable to described application.
Between development stage of the present invention, be surprised to find that when only using ethanol and fluorochemical surfactant, even also can obtain the foam of quick disruptive inflation, if and use traditional tensio-active agent, even under the percentage composition of twice, the also result that can only obtain differing greatly and at all can not obtain foam.
In order to realize the prescription of commercially practical, one of approach is to reduce the amount of used fluorochemical surfactant, use other composition that in makeup, aerosol, toiletry, personal care etc., uses simultaneously, for example ancillary components such as cosurfactant, emulsifying agent, suds-stabilizing agent, spices.One of commerical prod that is obtained uses as United States Patent (USP) the 5th, 167,950 and 6,090, disclosed emulsifying agent and polyethoxye lipid acid tensio-active agent in No. 395, these two pieces of patents are incorporated herein by reference, and other embodiment uses the combination of different foam stablizer to realize similar result.
The embodiment that can be used for the cosurfactant of the present composition comprises alkyl glucoside, poly-(ethoxylation and/or propoxylation) alcohol, poly-(ethoxylation and/or propoxylation) ester, the derivative of poly-(ethoxylation and/or propoxylation) alcohol, the derivative of poly-(ethoxylation and/or propoxylation) ester, alkyl alcohol, alkenyl alcohol, the ester of polyhydroxy-alcohol, the ether of polyhydroxy-alcohol, the ester of the poly-alkoxylation derivative of polyhydroxy-alcohol, the ether of the poly-alkoxylation derivative of polyhydroxy-alcohol, sorbitan fatty(acid)ester, the poly-alkoxylation derivative of sorbitan fatty(acid)ester, trimethyl-glycine, sultaine, imidazolidine derivatives, amino acid derivative, Yelkin TTS, phosphatide, amine oxide and sulfoxide and their mixture, the consumption of these cosurfactants at about 0.10 weight % between about 5 weight %.
Preferred trimethyl-glycine is AMONYL 380LC (cocaidopropyl betaine).Preferred alkyl glucoside is the cocoyl glucoside.Preferred polyethoxylated fatty alcohol is the combination of polyethoxylated stearyl alcohol (21 moles of ethylene oxide) and polyethoxylated stearyl alcohol (2 moles of ethylene oxide) and these two kinds of alcohol.
The present composition can comprise antiseptic-germicide.As the limiting examples that is used for suitable antiseptic-germicide of the present invention, described antiseptic-germicide can comprise form complexed, chlorxylone, triclosan, Hexachlorophene, phenol, the tensio-active agent with long-chain hydrophobic group and quaternary groups, hydrogen peroxide, silver, silver salt, silver suboxide and their mixture of chlorhexidine salt, iodine, iodine.
Preferred antiseptic-germicide is chlorhexidine gluconate (CHG) in the present composition, its consumption at about 0.50 weight % between about 4.0 weight %.Another kind of preferred antiseptic-germicide is chlorination didecyl dimethyl two ammoniums, its consumption at about 0.05 weight % between about 5 weight %.
Thereby after using, one or many can after the composition evaporation, not stay the sensation that is clamminess less if the consumption of each composition is enough, and this is to realize under the situation of keeping at least 60 volume % ethanol or n-propyl alcohol concentration or 70 volume % Virahols, and said composition will be an ideal for being used as pure hand sanitizing fluid/sterilizing agent foaming composition so.
In alcohol, add the more stable foam of water generates, can reduce the amount that makes the required fluorochemical surfactant of product foaming simultaneously.For instance, under 50 to 60 volume % alcohol solutions, use 0.5 to 1.0% fluorochemical surfactant to produce stable foam, even this foam is not easy to subside and produces and also can not fall down when counter-rotating and (for example when in hand or when rubbing from the teeth outwards) just subsides when exerting pressure stable ejecta (puff), thereby alcohol-group liquid solution is provided.
According to employed fluorochemical surfactant, use non-irritating tensio-active agent (for example AMONYL 380LC) of widely used gentleness in cosmetic industry is more suitable for preparing foaming water-alcohol composition of the present invention as cosurfactant.
For stable foam, attempted using suds-stabilizing agent and emulsified component, when product not being used under the situation of propelling agent and/or pressurizing vessel system provide, obtained good result as foam.
The example that can choose the compatible suds-stabilizing agent of use wantonly comprises the lactate of monoglyceride, cationic emulsifier, the stearic phosphatide complex compound of three quaternized (triquatemized), hydroxyl stearylamide the third three amine salt, lactic acid monoglyceride, food emulsifier, for example glyceryl monostearate, propylene glycol monostearate, stearoyl lactate, silicone wax, the oil of sealing, microcapsule mineral oil.
The preferred foams stablizer that is used for foaming composition of the present invention is a cetyl betaine.The preferred foam combination of stabilizers is butyleneglycol, butyl cellosolve and n-propyl alcohol.
The benefit humectant that can use in the present invention's prescription and/or the example of softener comprise lanolin; Vinyl alcohol; Polyvinylpyrolidone (PVP); Be selected from the polyvalent alcohol of glycerine, propylene glycol, olein and Sorbitol Powder; The cocoyl glucoside; Be selected from the fatty alcohol of hexadecanol, stearyl alcohol, lauryl alcohol, tetradecyl alcohol and palmityl alcohol; Hexadecanol; Ceteareth 20 (ceteareth 20) or their combination, its consumption is no more than about 5%.
The composition of being prepared as the foam granting can be stored in the uninflated sending trap, and described sending trap has the sending trap pump that is used for mixing said composition and air and provides foam by it.Described composition can comprise that consumption is about 3 to about 20% a aerosol propellants of total composition weight, discharges foam to be used for pressurization.Described aerosol propellants comprises propane, carbonic acid gas, butane, Refrigerant 12, dichloro tetrafluoro ethane, Perfluorocyclobutane, 1,1,1,2-Tetrafluoroethane, 1,1,1,2,3,3,3-heptafluoro-propane and 1,1,1,3,3,3 ,-HFC-236fa.In the time of in being stored in the metal vessel with propelling agent, described prescription can comprise corrosion inhibitor, for example Sorbic Acid, phenylformic acid, potassium sorbate and Sodium Benzoate, and its consumption is about 0.1% to about 5% of a total composition weight.
Gel-form composition
What have in the composition of being studied has gel character.This characteristic causes second kind of most important achievement of the present invention, promptly do not use the viscosity of traditional polymer thickening material (being derivatived cellulose, carbomer etc.) to be lower than 4, the alcogel of 000cps, these thickening materials are known in and stay cumulative viscosity remnants when one or many is used from the teeth outwards.This can make the user feel not well and be easy to stop up sending trap.
In order to prepare gel-form composition, do not need fluorochemical surfactant to form gel, still a small amount of meeting of use improves the sensation after using, and can also reduce the consumption of other tensio-active agent, therefore improves the performance of described composition.But the use of fluorochemical surfactant has also obviously improved the gel sanitizing composition on hand or lip-deep spreadability.
Be the basic recipe of described gel-form composition below: consumption is the C greater than about 40 volume % of total composition 1-4Alcohol or its mixture; Consumption is at about 0.10 weight % one or more nonionogenic tensides between about 5 weight %; Consumption is at the emulsifying agent of about 0.10 weight % between about 3.0 weight %; And consumption is enough to form the water of stable gel shape composition.
The limiting examples of nonionogenic tenside comprises poly-(ethoxylation and/or propoxylation) alcohol, poly-(ethoxylation and/or propoxylation) ester, the derivative of poly-(ethoxylation and/or propoxylation) alcohol, the derivative of poly-(ethoxylation and/or propoxylation) ester, alkyl alcohol, alkenyl alcohol, the ester of polyhydroxy-alcohol, the ether of polyhydroxy-alcohol, the ester of the poly-alkoxylation derivative of polyhydroxy-alcohol, the ether of the poly-alkoxylation derivative of polyhydroxy-alcohol, sorbitan fatty(acid)ester, the poly-alkoxylation derivative of sorbitan fatty(acid)ester and their mixture.
Preferred nonionic comprises the polyethoxylated fatty alcohol, for example polyethoxylated stearyl alcohol (21 moles of ethylene oxide) and polyethoxylated stearyl alcohol (2 moles of ethylene oxide); And/or the combination of polyethoxylated fatty alcohol.
Use for described gel-form composition being used for Personal hygiene, said composition can comprise and is no more than about 2.5% physiologically acceptable fluorochemical surfactant.Preferred fluorochemical surfactant is the tensio-active agent that uses in gel-form composition, i.e. tetrafluoroethylene acetoxyl group CAB:
(CF 3CF 2(CF 2CF 2) nCH 2CH 2(OAc) CH 2N +(CH 3) 2CH 2COO -), n=2-4 in the formula.
Another kind of preferred fluorochemical surfactant is the nonionic fluorochemical surfactant with ethoxylation of following structure: RfCH 2CH 2O (CH 2CH 2O) xH, wherein Rf=F (CF 2CF 2) y, x=0 is to about 15, and y=1 is to about 7; And another kind is to have the anion phosphate fluorochemical surfactant of following structure or their mixture again: (RfCH 2CH 2O) xP (O) (ONH 4) y, Rf=F (CF in the formula 2CF 2) z, x=1 or 2, y=2 or 1, x+y=3, and z=1 is to about 7; Perhaps their mixture.
Provide following non-limiting example showing each embodiment preferred, and these embodiment limit the scope of the invention never.
Embodiment
Use different tensio-active agents and water and 50% alcoholic acid formulations prepared from solutions embodiment 1 to 12, set forth to produce the ability of the pure based formulas that can provide with form of foam.The concentration of embodiment 13 to 18 expressions increasing ethanol and fluorochemical surfactant is produced foam.Embodiment 19 to 30 has shown and uses the Virahol of different surfaces promoting agent and 70 volume % to produce the foamy ability.Except as otherwise noted, all umbers and percentage ratio are all by weight.
The consumption component Embodiment 1 Embodiment 2 Embodiment 3 Embodiment 4 Embodiment 5 Embodiment 6
S.D. pure 3-A fluorine-containing surfactant Cocoamidopropyl betaine (1) alkyl glucoside (2) alkyl glucoside (3) Glycomul L sorbitan sesquioleate deionized water 50.00 0.50 ------ ------ ------ ------ ------ 49.50 50.00 ------ 8.00 ------ ------ ------ ------ 42.00 50.00 ------ ------ 8.00 ------ ------ ------ 42.00 50.00 ------ ------ ------ 8.00 ------ ------ 42.00 50.00 ------ ------ ------ ------ 8.00 ------ 42.00 50.00 ------ ------ ------ ------ ------ 8.00 42.00
Amount to % 100.00 100.00 100.00 100.00 100.00 100.00
(1) both sexes, (2) nonionic, (3) anionic property
The consumption component Embodiment 7 Embodiment 8 Embodiment 9 Embodiment 10 Embodiment 11 Embodiment 12
S.D. the single You acid of pure 3-A polysorbate 20 polyoxyethylene list You acid sorbitan esters sorbitan esters Ye oleamide propyl group Tian Cai Jian ﹠ Caproyllactic acid sodium cocamidopropyl propyl amide Qiang base sulfobetaines (Cocamidopropyl hydroxysultaine) cocounut oil Xian both sexes sodium acetates (Sodium Cocoamphoacetate) deionized water 50.00 8.00 ------ ------ ------ ------ ------ ------ ------ 42.00 50.00 ------ 8.00 ------ ------ ------ ------ ------ ------ 42.00 50.00 ------ ------ 8.00 ------ ------ ------ ------ ------ 42.00 50.00 ------ ------ ------ 8.00 ------ ------ ------ ------ 42.00 50.00 ------ ------ ------ ------ 8.00 ------ ------ ------ 42.00 50.00 ------ ------ ------ ------ ------ ------ 8.00 ------ 42.00
Amount to % 100.00 100.00 100.00 100.00 100.00 100.00
The consumption component Embodiment 13 Embodiment 14 Embodiment 15 Embodiment 16 Embodiment 17 Embodiment 18
S.D. pure 3-A fluorochemical surfactant deionized water 50.00 0.10 49.90 60.00 0.75 39.25 65.00 0.80 34.20 70.00 1.50 28.50 80.00 2.00 18.00 92.50 7.5 ------
Amount to % 100.00 100.00 100.00 100.00 100.00 100.00
The consumption component Embodiment 19 Embodiment 20 Embodiment 21 Embodiment 22 Embodiment 23 Embodiment 24
70 volume % isopropyl alcohol fluorine-containing surfactant Cocoamidopropyl betaine (1) alkyl glucoside (2) alkyl glucoside (3) Glycomul L sorbitan sesquioleates 99.90 0.10 ------ ------ ------ ------ ------ 92.00 ------ 8.00 ------ ------ ------ ------ 92.00 ------ ------ 8.00 ------ ------ ------ 92.00 ------ ------ ------ 8.00 ------ ------ 92.00 ------ ------ ------ ------ 8.00 ------ 92.00 ------ ------ ------ ------ ------ 8.00
Amount to % 100.00 100.00 100.00 100.00 100.00 100.00
(1) both sexes, (2) nonionic, (3) anionic property
The consumption component Embodiment 25 Embodiment 26 Embodiment 27 Embodiment 28 Embodiment 29 Embodiment 30
The single You acid of 70 volume % isopropyl alcohol polysorbate 20 polyoxyethylene list You acid sorbitan esters sorbitan esters Ye oleamide propyl group Tian Cai Jian ﹠ Caproyllactic acid sodium cocamidopropyl propyl amide Qiang base sulfobetaines (Cocamidopropyl hydroxysultaine) cocounut oil Xian both sexes sodium acetates (Sodium Cocoamphoacetate) 92.00 8.00 ------ ------ ------ ------ ------ ------ ------ 92.00 ------ 8.00 ------ ------ ------ ------ ------ ------ 92.00 ------ ------ 8.00 ------ ------ ------ ------ ------ 92.00 ------ ------ 8.00 ------ ------ ------ ------ 92.00 ------ ------ ------ ------ 8.00 ------ ------ ------ 92.00 ------ ------ ------ ------ ------ ------ 8.00 ------
Amount to % 100.00 100.00 100.00 100.00 100.00 100.00
Estimate prepared solution and whether produce foam, and if the generation foam, the foam that then following description produced:
Embodiment Produce foam Foam estimate/illustrates/characteristic
Embodiment 1 embodiment 2 embodiment 3 embodiment 4 embodiment 5 embodiment 6 embodiment 7 embodiment 8 embodiment 9 embodiment 10 embodiment 11 embodiment 12 embodiment 13 embodiment 14 embodiment 15 embodiment 16 embodiment 17 embodiment 18 embodiment 19 embodiment 20 embodiment 21 embodiment 22 embodiment 23 embodiment 24 embodiment 25 embodiment 26 embodiment 27 embodiment 28 embodiment 29 embodiment 30 Whether no no whether no no Very good, stable and endure ejecta, butteriness and soft, lasting several minutes only produces very wet (wet) bubble,------------------------------------------------------------------only produces very wet bubble to continue＜10 seconds, continue＜7 seconds only very wet bubbles of generation,------------------------only produces very wet bubble to continue＜10 seconds,--------------------------------------------------------------is very good to continue＜10 seconds, stable and endure ejecta, butteriness and soft, it is very good to continue several minutes, butteriness and soft, lasting one minute very good, butteriness and soft, lasting one minute very good, butteriness and soft, continue one minute quick disruptive bubble, continue quick disruptive bubble more than 15 seconds, continue quick disruptive bubble more than 10 seconds, continue more than 20 seconds-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Comparatively speaking, also find for instance, if use AMONYL 380LC (CAPB) separately, even under 40% ethanol and 3%CAPB, also can't produce and use 60 volume % ethanol and the obtained result of the fluorochemical surfactant of percentage composition (being less than 1.0%) still less.If the alcohol amount of containing is higher than described percentage composition, uses AMONYL 380LC also can't obtain acceptable foam, and be lower than 60 volume % and contain the alcohol amount and make it be not suitable for sterilized solution.In addition, described solution stays unacceptable sensation (being clammy stickiness feeling) in alcohol evaporation back on skin, and this shows the surfactant content height.
Absorbingly be that fluorochemical surfactant seemingly realizes comprising the possible approach of the foaming composition of the above alcohol of 40 volume %.Shown in embodiment 18,, can realize that also the foamy fact makes the present invention be applicable to many different application even when except the pure and mild fluorochemical surfactant of 95 volume %, not adding water or other composition.
Be to use the specific embodiment of above-mentioned prescription below with the some compositions of producing pure hand sanitizing fluid (alcohol hand sanitizingsolution); More than one are that to have only alcohol be the foaming composition of sterilizing agent composition, and other foaming composition uses the antiseptic-germicide that adds, for example chlorhexidine digluconate or chlorination didecyl dimethyl two ammoniums, and the 3rd group be alcogel shape hand sanitizing fluid (alcohol gel-like hand sanitizing solution).
Embodiment 31
The alcohol radical foaming sanitizing composition of washing one's hands
0.01-1.0%* both sexes, negatively charged ion or nonionic fluorochemical surfactant (main surface
Promoting agent)
0.01-1.0% AMONYL 380LC (cosurfactant)
0.05-1.0% spermaceti base trimethyl-glycine (suds-stabilizing agent)
The emulsifying agent aliphatic series alcohol roh that 0.10-1.5% well plays a role in end formulation
16-22 carbon or its combination
60-70 volume % ethanol
Q.S. water
Preferably polytetrafluoroethylene acetoxyl group CAB (CF 3CF 2(CF 2CF 2) nCH 2CH 2(OAc) CH 2N +(CH 3) 2CH 2COO -), n=2-4 in the formula; The nonionic fluorochemical surfactant that perhaps has the ethoxylation of following structure: RfCH 2CH 2O (CH 2CH 2O) xH, wherein Rf=F (CF 2CF 2) y, x=0 is to about 15, and y=1 is to about 7; Perhaps have the anion phosphate fluorochemical surfactant of following structure or their mixture: (RfCH 2CH 2O) xP (O) (ONH 4) y, Rf=F (CF in the formula 2CF 2) z, x=1 or 2, y=2 or 1, x+y=3, and z=1 is to about 7; Perhaps their mixture.
Embodiment 32
The alcohol radical foaming sanitizing composition concentrated solution of washing one's hands
0.01-1.0%* ampholytic anionic or nonionic fluorochemical surfactant (main surface
Promoting agent)
0.01-12.0% 1,3 butylene glycol, butoxy ethanol, n-propyl alcohol (suds-stabilizing agent)
0.05-5.0% cocoyl glucoside, glycerine, olein (are mended humectant, softener
Deng)
60-70 volume % ethanol, n-propyl alcohol, Virahol or its combination
Q.S. water
Preferably have the anion phosphate fluorochemical surfactant of following structure or their mixture: (RfCH 2CH 2O) xP (O) (ONH 4) y, Rf=F (CF in the formula 2CF 2) z, x=1 or 2, y=2 or 1, x+y=3, and z=1 is to about 7; The nonionic fluorochemical surfactant that perhaps has the ethoxylation of following structure: RfCH 2CH 2O (CH 2CH 2O) xH, wherein Rf=F (CF 2CF 2) y, x=0 is to about 15, and y=1 is to about 7; Perhaps tetrafluoroethylene acetoxyl group CAB (CF 3CF 2(CF 2CF 2) nCH 2CH 2(OAc) CH 2N +(CH 3) 2CH 2COO -), n=2-4 in the formula; Perhaps their mixture.
Embodiment 33
The alcohol radical foaming sanitizing composition of washing one's hands
A) consumption is the ethanol of about 60% to 70 volume % of total composition;
B) consumption is the physiologically acceptable anion phosphate fluorochemical surfactant of about 0.01 weight % of total composition to about 2.0 weight %;
C) at least 1% n-propyl alcohol;
D) comprise the suds-stabilizing agent of the butyl cellosolve of 2% 1,3 butylene glycol, about 0.001-3% at least;
E) the lipid layer toughener of the mixture of alkyl glucoside and olein for example; And
F) make total composition reach the water of the surplus of 100 weight %.
Embodiment 34
Chlorhexidine gluconate (CHG) ﹠amp; The alcohol radical foaming sanitizing composition of washing one's hands
Prescription 31 or 32 adds
0.50-4.0% chlorhexidine gluconate (CHG)
Embodiment 35
Prescription 31 or 32 adds
0.01-5.0% chlorination didecyl dimethyl two ammoniums
Embodiment 36
Viscosity is lower than 4, the alcohol radical of the 000cps gel sanitizing composition of washing one's hands
0.01-1.0%* both sexes, negatively charged ion or nonionic fluorochemical surfactant (main surface
Promoting agent)
The 0.10-2.0% emulsifying agent is mended humectant and/or softener, preferred nonionic surfactivity
Agent and/or spermaceti stearyl alcohol and ceteareth-20 or they
Combination, be lower than 4 to obtain viscosity, the composition of 000cps
0.50-4.0% is selected from the combination of the nonionogenic tenside of polyethoxylated fatty alcohol
60-70 volume % ethanol
Q.S. water
Preferably polytetrafluoroethylene acetoxyl group CAB (CF 3CF 2(CF 2CF 2) nCH 2CH 2(OAc) CH 2N +(CH 3) 2CH 2COO -), n=2-4 in the formula; The nonionic fluorochemical surfactant that perhaps has the ethoxylation of following structure: RfCH 2CH 2O (CH 2CH 2O) xH, wherein Rf=F (CF 2CF 2) y, x=0 is to about 15, and y=1 is to about 7; Perhaps have the anion phosphate fluorochemical surfactant of following structure or their mixture: (RfCH 2CH 2O) xP (O) (ONH 4) y, Rf=F (CF in the formula 2CF 2) z, x=1 or 2, y=2 or 1, x+y=3, and z=1 is to about 7; Perhaps their mixture.
Because most of compositions are liquid, so the method for preparing the present composition described herein is flat-footed.When using the wax pattern composition, preferably by being heated to 40-45 ℃ with in its adding alcohol moiety, mix simultaneously and also make its cooling subsequently, perhaps before adding any other composition, at room temperature add in the alcohol, and before all the other compositions that add according to described composition, be mixed to fully and merged with " cold " state.No matter whether all the components is liquid, and being heated to 80 degrees centigrade (depending on specific composition) from 30 has increased the permanent stability of composition.Activeconstituents can be dissolved in the water at first in advance.There is not the problem of enforcement in any technician's known method in this area.If can not regulate the percentage composition of each composition in the concrete prescription for foaming composition, so still can adjust the foaming pump characteristic, for example change pressure, screen size etc.
The composition of describing among the present invention high determining alcohol and following aspect improved commercially available existing analogous products, itself in addition also can foam under propelling agent or the pressurizing vessel not having, and by its alcogel shape composition that makes after one or many is used, can not stay cumulative with after the sensation that is clamminess and can not stop up sending trap.
According to the concentration of alcohol and the application-specific of composition, the foam of being produced can change widely, as high-end be comparatively fast to break and thereby stable being enough to spreads over not wasting product on the skin fully with unique mode, and the viscosity of described gel-form composition changes along with determining alcohol.The gel-form composition of gained has adopted the unique approach that is different from the traditional method of making alcogel.In a word, we can say that the present invention has surpassed expection.
Because the characteristic of described base composition aspect determining alcohol and composition quality, the application that the present invention stands in the breach is exactly to be used for the alcohol radical of foamed products or the alcogel shape product sanitizing composition of washing one's hands, and embodiment as mentioned above.But the present invention helps to prepare a large amount of products, and is to be understood that and can uses other embodiment, and can make a change and can not deviate from scope of the present invention.
Therefore, the application's claim should contain these modifications and equivalence.In brief, can mention these points: pharmaceutical foam and gel, sun-proof foam and gel, hand lotion foam, brush type (brush-less) shaving cream foam, shower or bath oil foam, dry hair shampoo foam, makeup removing foam, the wiping of pain relieving foam and gel, hair ornamenting foam and anti-sweat hair foam cleaner, anti-sweat foam, hair conditioner foam less.
Term used herein " comprises ", " it comprises ", " comprising " and " it comprises " should be construed as comprise and be open, and be not exclusiveness.Specifically, when using in the present specification that is comprising claim, term " comprises ", " it comprises ", " comprising " and " it comprises " and variant thereof mean and comprise concrete feature, step or component.
These terms should not be construed as the existence of having got rid of further feature, step or component.
Above-mentioned explanation provides the preferred embodiments of the invention, setting forth principle of the present invention, but this and do not mean that the present invention is subject to described specific embodiment.All embodiments and equivalence thereof that scope of the present invention should be comprised by appended claim are determined.
The document of quoting
American documentation literature
2,054,9899/1936 Moore..............................167/58
3,131,1534/1964 Klausner...........................252/305
3,962,1506/1976 Leonard etc.. ... ... ... ..252/542
4,440,6534/1984 James etc.. ... ... ... ... .252/8.55
5,167,95012/199 2Lins..............................424/47
4,956,17009/1990 Lee............................... 514/772.1
5,629,0065/1997 Minh etc.. ... ... ... ... ..424/405
5,906,8085/1999 Osbome etc.. ... ... ... .424/43
5,928,9937/1999 Ingegard......................504/116
5,951,99309/1999 Scholz etc.. ... ... ... .424/405
6,090,39507/2000 Asmus etc.. ... ... ... ..424/401
6,610,31508/2003 Scholz etc.. ... ... ... .424/415
6,623,74409/2003 Asmus etc.. ... ... ... ..424/401
6,562,36005/2003 Scholz etc.. ... ... ... .424/405
Other document
Myers, Drew; " Surfactant Science and Technology ", second edition, DrewMyers, VCH Publishers, New York, 1992;
Reduce Tension Dupont Zonyl  Fluorosurfactants Field Manual, Dupont company, May calendar year 2001.

Claims (117)

1. composition, it comprises:
A) C 1-4Alcohol or its mixture, its consumption is greater than about 40 volume % of total composition amount;
B) be used for effective fluorine-containing surfactants reagent wetting and foaming, its consumption is at least 0.001 weight % of total composition; And
C) make total composition reach the water of the surplus of 100 weight %.
2. the composition of claim 1, it comprises air, wherein when described composition and air mixed, described composition and AIR MIXTURES form foam.
3. claim 1 or 2 composition, wherein said effective fluorine-containing surfactants reagent is that consumption is about 0.001 fluorochemical surfactant to about 10.0 weight % of total composition.
4. claim 1,2 or 3 composition, wherein said effective fluorine-containing surfactants reagent is physiologically acceptable fluorochemical surfactant, and wherein said fluorochemical surfactant is selected from fluoro ethoxylate, glyceryl ester, amine oxide, propargyl alcohol derivative, carboxylicesters, phosphoric acid ester, carbohydrate derivates, sulphonate, trimethyl-glycine, ester, polymeric amide, organosilicon and hydrocarbon tensio-active agent.
5. claim 1,2,3 or 4 composition, wherein said C 1-4Alcohol is the fatty alcohol that is selected from methyl alcohol, ethanol, Virahol, n-propyl alcohol, butanols and their combination.
6. claim 1,2,3,4 or 5 composition, wherein said fluorochemical surfactant is an amphoteric tetrafluoroethylene acetoxyl group CAB:
(CF 3CF 2(CF 2CF 2) nCH 2CH 2(OAc) CH 2N +(CH 3) 2CH 2COO -), n=2 to 4 in the formula.
7. claim 1,2,3,4 or 5 composition, wherein said fluorochemical surfactant is the nonionic fluorochemical surfactant with ethoxylation of following structure:
RfCH 2CH 2O (CH 2CH 2O) xH, wherein Rf=F (CF 2CF 2) y, x=0 is to about 15, and y=1 is to about 7.
8. claim 1,2,3,4 or 5 composition, wherein said fluorochemical surfactant is to have the anion phosphate fluorochemical surfactant of following structure or their mixture: (RfCH 2CH 2O) xP (O) (ONH 4) y, Rf=F (CF in the formula 2CF 2) z, x=1 or 2, y=2 or 1, x+y=3, and z=1 is to about 7.
9. claim 1,2,3,4 or 5 composition, wherein said fluorochemical surfactant is the mixture of fluorochemical surfactant described in two or more claims 6,7 and 8.
10. claim 1,2,3,4,5,6,7,8 or 9 composition, the consumption of wherein said alcohol about 40% to the scope of about 90 volume %.
11. claim 1,2,3,4,5,6,7,8 or 9 composition, wherein said alcohol is the ethanol that consumption is at least 60 volume %, and wherein said composition is used as the pure foam of Personal hygiene.
12. claim 1,2,3,4,5,6,7,8 or 9 composition, wherein said alcohol is n-propyl alcohol and the alcoholic acid mixture that total consumption is at least 60 volume %, and wherein said composition is used as the pure foam of Personal hygiene.
13. claim 1,2,3,4,5,6,7,8 or 9 composition, wherein said alcohol is Virahol and the alcoholic acid mixture that total consumption is at least 60 volume %, and wherein said composition is used as the pure foam of Personal hygiene.
14. claim 1,2,3,4,5,6,7,8 or 9 composition, wherein said alcohol is the Virahol that consumption is at least 70 volume %, and wherein said composition is used as the pure foam of Personal hygiene.
15. claim 1,2,3,4,5,6,7,8 or 9 composition, wherein said alcohol is the n-propyl alcohol that consumption is at least 60 volume %, and wherein said composition is used as the pure foam of Personal hygiene.
16. claim 1,2,3,4,5,6,7,8,9,10,11,12,13,14 or 15 composition, it also comprises at least a additional surfactants that is used to regulate the foamy character that is produced by described composition.
17. the composition of claim 16, wherein said additional surfactants is selected from following material: poly-(ethoxylation and/or propoxylation) alcohol, poly-(ethoxylation and/or propoxylation) ester, the derivative of poly-(ethoxylation and/or propoxylation) alcohol, the derivative of poly-(ethoxylation and/or propoxylation) ester, alkyl alcohol, alkenyl alcohol, the ester of polyhydroxy-alcohol, the ether of polyhydroxy-alcohol, the ester of the poly-alkoxylation derivative of polyhydroxy-alcohol, the ether of the poly-alkoxylation derivative of polyhydroxy-alcohol, sorbitan fatty(acid)ester, the poly-alkoxylation derivative of sorbitan fatty(acid)ester, alkyl glucoside, trimethyl-glycine, sultaine, imidazolidine derivatives, amino acid derivative, Yelkin TTS, phosphatide, amine oxide, sulfoxide and their mixture, its consumption are that about 0.10 weight % is to about 5 weight %.
18. the composition of claim 17, wherein said trimethyl-glycine is an AMONYL 380LC.
19. the composition of claim 17, wherein said alkyl glucoside are the cocoyl glucosides.
20. the composition of claim 17, wherein said polyethoxylated fatty alcohol are polyethoxylated stearyl alcohol (21 moles of ethylene oxide).
21. the composition of claim 17, wherein said polyethoxylated fatty alcohol are polyethoxylated stearyl alcohol (2 moles of ethylene oxide).
22. the composition of claim 17, wherein said polyethoxylated fatty alcohol are the combinations of polyethoxylated stearyl alcohol (21 moles of ethylene oxide) and polyethoxylated stearyl alcohol (2 moles of ethylene oxide).
23. claim 1,2,3,4,5,6,7,8,9,10,11,12,13,14,15,16,17,18,19,20,21 or 22 composition, it comprises that consumption is no more than 5% suds-stabilizing agent.
24. the composition of claim 23, wherein said suds-stabilizing agent is selected from following material: the lactate of monoglyceride, cationic emulsifier, three quaternized stearic phosphatide complex compounds, hydroxyl stearylamide the third three amine salt, lactic acid monoglyceride, food emulsifier, for example glyceryl monostearate, propylene glycol monostearate, stearoyl lactate, spermaceti base trimethyl-glycine, glycol ether, n-propyl alcohol, butyleneglycol, silicone wax, the oil of sealing, microcapsule mineral oil and their combination.
25. the composition of claim 23, wherein said suds-stabilizing agent are selected from glycol ether, n-propyl alcohol, butyleneglycol and their combination.
26. the composition of any one in the claim 1 to 25, it comprises mends any in humectant, softener and their combination, and they are selected from following material: lanolin; Vinyl alcohol; Polyvinylpyrolidone (PVP); Be selected from the polyvalent alcohol of glycerine, propylene glycol, butyleneglycol and Sorbitol Powder; Be selected from the fatty alcohol of hexadecanol, stearyl alcohol, lauryl alcohol, tetradecyl alcohol and palmityl alcohol; Hexadecanol; Ceteareth 20; Alkyl glucoside and their combination, its consumption is no more than about 5%.
27. the composition of any one in the claim 1 to 26, its also comprise acid or alkali with the pH that regulates described composition to the pH that selects in advance, its consumption is that about 0.05 weight % of total composition is to about 0.5 weight %.
28. the composition of claim 27, wherein when using acid to regulate pH, described acid is selected from hydrochloric acid, citric acid and phosphoric acid, and wherein when use alkali is regulated pH, described alkali is concentrated crystal soda.
29. any one composition of claim 1 to 28, it comprises that consumption is the sanitas of about 0.01 weight % of total composition to about 5 weight %.
30. any one composition of claim 1 to 29, it comprises antiseptic-germicide.
31. the composition of claim 30, wherein said antiseptic-germicide are consumptions at about 0.50 weight % to the chlorhexidine gluconate between about 4.0 weight %.
32. the composition of claim 30, wherein said antiseptic-germicide are consumptions at about 0.50 weight % to chlorination didecyl dimethyl two ammoniums between about 5.0 weight %.
33. the composition of claim 30, wherein said antiseptic-germicide is selected from following material: the form complexed of chlorhexidine salt, iodine, iodine, chlorxylone, triclosan, Hexachlorophene, phenol, the tensio-active agent with long-chain hydrophobic group and quaternary groups, hydrogen peroxide, silver, silver salt, silver suboxide and their mixture.
34. any one composition of claim 1 to 33, it also comprises the component that is selected from following material: lower alkane alcohol amide, short-chain diol and/or the triol of organic natural gum and colloid, higher fatty acid, spices, pigment, UV light absorber, solvent, suspension agent, buffer reagent, conditioning agent, antioxidant, sterilant and medicinal actives composition and their combination.
35. the composition of any one in the claim 1 to 34, it is stored in the uninflated sending trap, and this sending trap has the sending trap pump that is used for mixing described composition and air and provides foam by it.
36. the composition of any one in the claim 1 to 34, it is stored in the uninflated sending trap, this sending trap has the sending trap pump that is used for mixing described composition and air or propelling agent and provides foam by it, and described composition comprises that consumption is the aerosol propellants of about 3 weight % of total composition to about 20 weight %.
37. the composition of claim 36, wherein said aerosol propellants are selected from propane, carbonic acid gas, butane, Refrigerant 12, dichloro tetrafluoro ethane, Perfluorocyclobutane, 1,1,1,2-Tetrafluoroethane, 1,1,1,2,3,3,3-heptafluoro-propane and 1,1,1,3,3,3 ,-HFC-236fa.
38. the composition of claim 36 or 37, it comprises corrosion inhibitor, and described corrosion inhibitor is selected from Sorbic Acid, phenylformic acid, potassium sorbate and Sodium Benzoate, and its consumption is that about 0.1 weight % of total composition is to about 5 weight %.
39. a composition concentrate, it comprises:
A) both sexes, negatively charged ion or nonionic fluorochemical surfactant, its consumption are about 0.01 to about 1.0%;
B) suds-stabilizing agent, it comprises the n-propyl alcohol at least about 0.01 to about 12.0%;
C) mend in humectant, softener and their combination one of any, its consumption about 0.05 to about 5.0% scope; And
D) water.
40. the composition concentrate of claim 39, wherein said both sexes, negatively charged ion or nonionic fluorochemical surfactant are structures is (RfCH 2CH 2O) xP (O) (ONH 4) yThe anion phosphate fluorochemical surfactant, Rf=F (CF wherein 2CF 2) z, x=1 or 2, y=2 or 1, x+y=3, and z=1 is to about 7; Perhaps structure is RfCH 2CH 2O (CH 2CH 2O) xThe nonionic fluorochemical surfactant of the ethoxylation of H, wherein Rf=F (CF 2CF 2) y, x=0 is to about 15, and y=1 is to about 7; Perhaps tetrafluoroethylene acetoxyl group CAB: CF 3CF 2(CF 2CF 2) nCH 2CH 2(OAc) CH 2N +(CH 3) 2CH 2COO -, n=2-4 in the formula; Perhaps their mixture.
41. the composition concentrate of claim 39 or 40, wherein said suds-stabilizing agent comprises 1,3 butylene glycol and butoxy ethanol.
42. claim 39,40 or 41 composition concentrate, wherein said benefit humectant and softener comprise cocoyl glucoside, glycerine and olein.
43. claim 39,40,41 or 42 composition concentrate, it constitutes pure sanitizing composition by adding following material:
A) C 1-4Alcohol or its mixture, its consumption total composition about 60 to about 80 volume % between;
C) make total composition reach the water of the surplus of 100 weight %.
44. the composition concentrate of claim 43, wherein said C 1-4Alcohol is selected from ethanol, n-propyl alcohol, Virahol and their combination.
45. the composition concentrate of any one in the claim 39 to 44, it prepares by the method for mixing each component and before the described enriched material of shipment this enriched material is heated between about 30 to about 80 degrees centigrade subsequently.
46. a pure sanitizing composition, it comprises:
A) C 1-4Alcohol or its mixture, its consumption total composition about 60 to about 80 volume % between;
B) physiologically acceptable fluorochemical surfactant, its consumption are that about 0.01 weight % of total composition is to about 2.0 weight %;
C) suds-stabilizing agent, its consumption are about 0.01 to about 12.0 weight %;
D) mend in humectant, softener and their combination one of anyly, its consumption is about 0.05 to about 5.0 weight %; And
E) make total composition reach the water of the surplus of 100 weight %.
47. the pure sanitizing composition of claim 46, it comprises air, and wherein when described sanitizing composition and air mixed, this sanitizing composition and AIR MIXTURES form foam.
48. the pure sanitizing composition of claim 46 or 47, wherein said fluorochemical surfactant are amphoteric tetrafluoroethylene acetoxyl group CAB:
(CF 3CF 2(CF 2CF 2) nCH 2CH 2(OAc) CH 2N +(CH 3) 2CH 2COO -), n=2 to 4 in the formula.
49. the pure sanitizing composition of claim 46 or 47, wherein said fluorochemical surfactant are the nonionic fluorochemical surfactants with ethoxylation of following structure:
RfCH 2CH 2O (CH 2CH 2O) xH, wherein Rf=F (CF 2CF 2) y, x=0 is to about 15, and y=1 is to about 7.
50. the pure sanitizing composition of claim 46 or 47, wherein said fluorochemical surfactant are the anion phosphate fluorochemical surfactants with following structure:
(RfCH 2CH 2O) xP (O) (ONH 4) y, Rf=F (CF in the formula 2CF 2) z, x=1 or 2, y=2 or 1, x+y=3, and z=1 is to about 7.
51. the pure sanitizing composition of claim 46 or 47, wherein said fluorochemical surfactant are selected from the mixture of the fluorochemical surfactant described in fluoro ethoxylate, glyceryl ester, amine oxide, propargyl alcohol derivative, carboxylicesters, phosphoric acid ester, carbohydrate derivates, sulphonate, trimethyl-glycine, ester, polymeric amide, organosilicon, hydrocarbon tensio-active agent and two or more claims 47,48 and 49.
52. claim 46,47,48,49,50 or 51 pure sanitizing composition, wherein said suds-stabilizing agent is selected from following material: the lactate of monoglyceride, cationic emulsifier, three quaternized stearic phosphatide complex compounds, hydroxyl stearylamide the third three amine salt, lactic acid monoglyceride, food emulsifier, for example glyceryl monostearate, propylene glycol monostearate, stearoyl lactate, silicone wax, the oil of sealing, microcapsule mineral oil, butyleneglycol, butyl cellosolve and/or n-propyl alcohol and their mixture.
53. the pure sanitizing composition of any one in the claim 46,47,48,49,50 or 51, wherein said suds-stabilizing agent is selected from butyl cellosolve, glycol ether, n-propyl alcohol, butyleneglycol and their combination.
54. claim 46,47,48,49,50,51,52 or 53 pure sanitizing composition, it comprises mends any in humectant, softener and their combination, and they are selected from following material: lanolin; Vinyl alcohol; Polyvinylpyrolidone (PVP); Be selected from the polyvalent alcohol of glycerine, propylene glycol, butyleneglycol and Sorbitol Powder; Be selected from the fatty alcohol of hexadecanol, stearyl alcohol, lauryl alcohol, tetradecyl alcohol and palmityl alcohol; Hexadecanol; Ceteareth 20; Alkyl glucoside and their combination, its consumption is no more than about 5%.
55. claim 46,47,48,49,50,51,52 or 53 pure sanitizing composition, it comprises benefit humectant and the softener that is selected from olein, glycerine, cocoyl glucoside and their combination.
56. claim 46,47,48,49,50,51,52,53,54 or 55 pure sanitizing composition, it comprises antiseptic-germicide.
57. the pure sanitizing composition of claim 56, wherein said antiseptic-germicide are consumptions at about 0.50 weight % to the chlorhexidine gluconate between about 4.0 weight %.
58. the pure sanitizing composition of claim 56, wherein said antiseptic-germicide are consumptions at about 0.50 weight % to chlorination didecyl dimethyl two ammoniums between about 5.0 weight %.
59. the pure sanitizing composition of claim 56, wherein said antiseptic-germicide is selected from following material: the form complexed of chlorhexidine salt, iodine, iodine, chlorxylone, triclosan, Hexachlorophene, phenol, the tensio-active agent with long-chain hydrophobic group and quaternary groups, hydrogen peroxide, silver, silver salt, silver suboxide and their mixture.
60. the pure sanitizing composition of any one in the claim 46 to 59, it comprises that consumption is the sanitas of about 0.01 weight % of total composition to about 5 weight %.
61. the pure sanitizing composition of any one in the claim 46 to 59, it comprises that consumption is the sanitas of about 0.01 weight % of total composition to about 5 weight %.
62. the pure sanitizing composition of any one in the claim 46 to 61, its also comprise acid or alkali with the pH that regulates described composition to the pH that selects in advance, its consumption is that about 0.05 weight % of total composition is to about 0.5 weight %.
63. the composition of claim 62, wherein said acid is selected from hydrochloric acid, citric acid and phosphoric acid, and described alkali is concentrated crystal soda.
64. the pure sanitizing composition of any one in the claim 46 to 63, it is stored in the uninflated sending trap, and this sending trap has the sending trap pump that is used for mixing described sanitizing composition and air and provides foam by it.
65. the pure sanitizing composition of any one in the claim 46 to 63, it is stored in the uninflated sending trap, this sending trap has the sending trap pump that is used for mixing described sanitizing composition and air or propelling agent and provides foam by it, and described sanitizing composition comprises that consumption is the aerosol propellants of about 3 weight % of total composition to about 20 weight %.
66. the pure sanitizing composition of claim 65, wherein said aerosol propellants are selected from propane, carbonic acid gas, butane, Refrigerant 12, dichloro tetrafluoro ethane, Perfluorocyclobutane, 1,1,1,2-Tetrafluoroethane, 1,1,1,2,3,3,3-heptafluoro-propane and 1,1,1,3,3,3 ,-HFC-236fa.
67. the pure sanitizing composition of claim 65 or 66, it comprises corrosion inhibitor, and described corrosion inhibitor is selected from Sorbic Acid, phenylformic acid, potassium sorbate and Sodium Benzoate, and its consumption is that about 0.1 weight % of total composition is to about 5 weight %.
68. the pure sanitizing composition of any one in the claim 46 to 67, it comprises mends any in humectant, softener and their combination, and they are selected from following material: lanolin; Vinyl alcohol; Polyvinylpyrolidone (PVP); Be selected from the polyvalent alcohol of glycerine, propylene glycol, butyleneglycol and Sorbitol Powder; Be selected from the fatty alcohol of hexadecanol, stearyl alcohol, lauryl alcohol, tetradecyl alcohol and palmityl alcohol; Hexadecanol; Ceteareth 20; Alkyl glucoside and their combination, its consumption is no more than about 5%.
69. the pure sanitizing composition of any one in the claim 46 to 68, it also comprises other component or the material that can be added to usually in aerosol composition, toiletry, makeup and the medicine, comprises that mixture, suspension agent, buffer reagent, conditioning agent, antioxidant, sterilant, the medicinal actives of lower alkane alcohol amide, short-chain diol and/or triol, spices, pigment, additional softener, UV light absorber, solvent, emulsifying agent, suds-stabilizing agent or this stablizer of organic natural gum and colloid, higher fatty acid becomes to grade.
70. a pure sanitizing composition, it comprises:
A) ethanol, its consumption is between about 60 to 70 volume % of total composition;
B) physiologically acceptable fluorochemical surfactant or its mixture, its consumption are that about 0.01 weight % of total composition is to about 2.0 weight %;
C) at least a cosurfactant, its consumption are about 0.01 to about 10.0 weight %;
D) suds-stabilizing agent; And
E) make total composition reach the water of the surplus of 100 weight %.
71. the pure sanitizing composition of claim 70, wherein said fluorochemical surfactant are amphoteric tetrafluoroethylene acetyl oxygen CAB:
(CF 3CF 2(CF 2CF 2) nCH 2CH 2(OAc) CH 2N +(CH 3) 2CH 2COO -), n=2 to 4 in the formula.
72. the pure sanitizing composition of claim 70, wherein said fluorochemical surfactant are the nonionic fluorochemical surfactants with ethoxylation of following structure:
RfCH 2CH 2O (CH 2CH 2O) xH, wherein Rf=F (CF 2CF 2) y, x=0 is to about 15, and y=1 is to about 7.
73. the pure sanitizing composition of claim 70, wherein said fluorochemical surfactant are the anion phosphate fluorochemical surfactants with following structure:
(RfCH 2CH 2O) xP (O) (ONH 4) y, Rf=F (CF in the formula 2CF 2) z, x=1 or 2, y=2 or 1, x+y=3, and z=1 is to about 7.
74. the pure sanitizing composition of claim 70, wherein said fluorine-containing surfactants reagent is selected from the mixture of the fluorochemical surfactant described in fluoro ethoxylate, glyceryl ester, amine oxide, propargyl alcohol derivative, carboxylicesters, phosphoric acid ester, carbohydrate derivates, sulphonate, trimethyl-glycine, ester, polymeric amide, organosilicon, hydrocarbon tensio-active agent and two or more claims 71,72 and 73.
75. claim 70,71,72,73 or 74 pure sanitizing composition, wherein said cosurfactant is selected from following material: poly-(ethoxylation and/or propoxylation) alcohol, poly-(ethoxylation and/or propoxylation) ester, the derivative of poly-(ethoxylation and/or propoxylation) alcohol, the derivative of poly-(ethoxylation and/or propoxylation) ester, alkyl alcohol, alkenyl alcohol, the ester of polyhydroxy-alcohol, the ether of polyhydroxy-alcohol, the ester of the poly-alkoxylation derivative of polyhydroxy-alcohol, the ether of the poly-alkoxylation derivative of polyhydroxy-alcohol, sorbitan fatty(acid)ester, the poly-alkoxylation derivative of sorbitan fatty(acid)ester, alkyl glucoside, trimethyl-glycine, sultaine, imidazolidine derivatives, amino acid derivative, Yelkin TTS, phosphatide, amine oxide, sulfoxide and their mixture, its consumption are that about 0.10 weight % is to about 5 weight %.
76. claim 70,71,72,73 or 74 pure sanitizing composition, wherein said cosurfactant is an AMONYL 380LC.
77. claim 70,71,72,73,74,75 or 76 pure sanitizing composition, it comprises the mixture of emulsifying agent or emulsifying agent, its consumption at about 0.10 weight % between about 1.5 weight %.
78. the pure sanitizing composition of claim 77, wherein said emulsifying agent are spermaceti ether and on average have about 20 mixtures that contain the stearyl ether of oxygen unitary poly-(oxyethane).
79. claim 70,71,72,73,74,75,76,77 or 78 pure sanitizing composition, wherein said suds-stabilizing agent is a spermaceti base trimethyl-glycine.
80. claim 70,71,72,73,74,75,76,77,78 or 79 pure sanitizing composition, it comprises antiseptic-germicide.
81. the pure sanitizing composition of claim 80, wherein said antiseptic-germicide are consumptions at about 0.50 weight % to the chlorhexidine gluconate between about 4.0 weight %.
82. the pure sanitizing composition of claim 80, wherein said antiseptic-germicide are consumptions at about 0.50 weight % to chlorination didecyl dimethyl two ammoniums between about 5.0 weight %.
83. the pure sanitizing composition of claim 82, wherein said antiseptic-germicide is selected from following material: the form complexed of chlorhexidine salt, iodine, iodine, chlorxylone, triclosan, Hexachlorophene, phenol, the tensio-active agent with long-chain hydrophobic group and quaternary groups, hydrogen peroxide, silver, silver salt, silver suboxide and their mixture.
84. claim 70,71,72,73,74,75,76,77,78,79,80,81,82 or 83 pure sanitizing composition, it comprises that consumption is the sanitas of about 0.01 weight % of total composition to about 5 weight %.
85. claim 70,71,72,73,74,75,76,77,78,79,80,81,82 or 83 pure sanitizing composition, it comprises that consumption is the sanitas of about 0.01 weight % of total composition to about 5 weight %.
86. the pure sanitizing composition of any one in the claim 70 to 85, its also comprise acid or alkali with the pH that regulates described sanitizing composition to the pH that selects in advance, its consumption is that about 0.05 weight % of total composition is to about 0.5 weight %.
87. the pure sanitizing composition of claim 86, wherein said acid is selected from hydrochloric acid, citric acid and phosphoric acid, and described alkali is concentrated crystal soda.
88. the pure sanitizing composition of any one in the claim 70 to 87, it is stored in the uninflated sending trap, and this sending trap has the sending trap pump that is used for mixing described sanitizing composition and air and provides foam by it.
89. the pure sanitizing composition of any one in the claim 70 to 87, it is stored in the uninflated sending trap, this sending trap has the sending trap pump that is used for mixing described sanitizing composition and air or propelling agent and provides foam by it, and described sanitizing composition comprises that consumption is the aerosol propellants of about 3 weight % of total composition to about 20 weight %.
90. the pure sanitizing composition of claim 89, wherein said aerosol propellants are selected from propane, carbonic acid gas, butane, Refrigerant 12, dichloro tetrafluoro ethane, Perfluorocyclobutane, 1,1,1,2-Tetrafluoroethane, 1,1,1,2,3,3,3-heptafluoro-propane and 1,1,1,3,3,3 ,-HFC-236fa.
91. the pure sanitizing composition of claim 89 or 90, it comprises corrosion inhibitor, and described corrosion inhibitor is selected from Sorbic Acid, phenylformic acid, potassium sorbate and Sodium Benzoate, and its consumption is that about 0.1 weight % of total composition is to about 5 weight %.
92. the pure sanitizing composition of any one in the claim 70 to 91, it comprises mends humectant and/or softener, and they are selected from following material: lanolin; Alkyl glucoside; Vinyl alcohol; Polyvinylpyrolidone (PVP); Be selected from the polyvalent alcohol of glycerine, propylene glycol, olein and Sorbitol Powder; Be selected from the fatty alcohol of hexadecanol, stearyl alcohol, lauryl alcohol, tetradecyl alcohol and palmityl alcohol; Hexadecanol; Ceteareth 20; And their combination, its consumption is no more than about 5 weight %.
93. the pure sanitizing composition of any one in the claim 70 to 92, it also comprises other component or the material that can be added to usually in aerosol composition, toiletry, makeup and the medicine, comprises that mixture, suspension agent, buffer reagent, conditioning agent, antioxidant, sterilant, the medicinal actives of lower alkane alcohol amide, short-chain diol and/or triol, spices, pigment, additional softener, UV light absorber, solvent, emulsifying agent, suds-stabilizing agent or this stablizer of organic natural gum and colloid, higher fatty acid becomes to grade.
94. the enriched material of the pure sanitizing composition of claim 43 or 44, it is by mixing each component and loading and transporting described enriched material subsequently, and at once, the method that this enriched material is heated between about 30 to about 80 degrees centigrade prepares before reformulating described enriched material with alcohol.
95. an alcogel shape composition, it comprises:
A) C 1-4Alcohol or its mixture, its consumption is greater than about 40 volume % of total composition;
B) at least a nonionogenic tenside, it is selected from following material: poly-(ethoxylation and/or propoxylation) alcohol, poly-(ethoxylation and/or propoxylation) ester, the derivative of poly-(ethoxylation and/or propoxylation) alcohol, the derivative of poly-(ethoxylation and/or propoxylation) ester, alkyl alcohol, alkenyl alcohol, the ester of polyhydroxy-alcohol, the ether of polyhydroxy-alcohol, the ester of the poly-alkoxylation derivative of polyhydroxy-alcohol, the ether of the poly-alkoxylation derivative of polyhydroxy-alcohol, sorbitan fatty(acid)ester, the poly-alkoxylation derivative of sorbitan fatty(acid)ester and their mixture, its consumption at about 0.10 weight % between about 5 weight %;
C) emulsifying agent, its consumption at about 0.10 weight % between about 3.0 weight %; And
D) water, its consumption are enough to form viscosity and are lower than 4, the stable gel composition of 000cps.
96. the alcogel shape composition of claim 95, it comprises and is used for wetting effective fluorine-containing surfactants reagent.
97. the alcogel shape composition of claim 96, wherein said fluorine-containing surfactants reagent is the fluorochemical surfactant that is selected from following material: fluoro ethoxylate, glyceryl ester, amine oxide, propargyl alcohol derivative, carboxylicesters, phosphoric acid ester, carbohydrate derivates, sulphonate, trimethyl-glycine, ester, polymeric amide, organosilicon, hydrocarbon tensio-active agent.
98. the alcogel shape composition of claim 96, wherein said effective fluorine-containing surfactants reagent are amphoteric tetrafluoroethylene acetyl oxygen CAB:
(CF 3CF 2(CF 2CF 2) nCH 2CH 2(OAc) CH 2N +(CH 3) 2CH 2COO -), n=2 to 4 in the formula, its consumption are that about 0.001 weight % is to about 2.5.
99. the alcogel shape composition of claim 96, wherein said effective fluorine-containing surfactants reagent has the nonionic fluorochemical surfactant of the ethoxylation of following structure:
RfCH 2CH 2O (CH 2CH 2O) xH, wherein Rf=F (CF 2CF 2) y, x=0 is to about 15, and y=1 is to about 7, and its consumption is that about 0.001 weight % is to about 2.5.
100. the alcogel shape composition of claim 96, wherein said effective fluorine-containing surfactants reagent has the anion phosphate fluorochemical surfactant of following structure:
(RfCH 2CH 2O) xP (O) (ONH 4) y, Rf=F (CF in the formula 2CF 2) z, x=1 or 2, y=2 or 1, x+y=3, and z=1 is to about 7, and its consumption is that about 0.001 weight % is to about 2.5.
101. the alcogel shape composition of claim 96, wherein said effective fluorine-containing surfactants reagent are the mixtures of two or more fluorochemical surfactants described in the claim 96,97 or 98, its consumption is that about 0.001 weight % is to about 2.5.
102. the alcogel shape composition of any one in the claim 95 to 101, wherein said C 1-4Alcohol is the fatty alcohol that is selected from methyl alcohol, ethanol, 2-propyl alcohol and butanols.
103. the alcogel shape composition of any one in the claim 95 to 101, wherein said at least a nonionogenic tenside is the polyethoxylated fatty alcohol, this polyethoxylated fatty alcohol is polyethoxylated stearyl alcohol (21 moles of ethylene oxide), its consumption is 0.1% to 5%, so that having, final sanitizing composition is lower than 4, the final viscosity of 000cps.
104. the alcogel shape composition of any one in the claim 95 to 101, wherein said at least a nonionogenic tenside is the polyethoxylated fatty alcohol, this polyethoxylated fatty alcohol is polyethoxylated stearyl alcohol (2 moles of ethylene oxide), its consumption is 0.1% to 5%, so that having, final sanitizing composition is lower than 4, the final viscosity of 000cps.
105. the alcogel shape composition of any one in the claim 95 to 101, wherein said at least a nonionogenic tenside is the combination of polyethoxylated stearyl alcohol (21 moles of ethylene oxide) and polyethoxylated stearyl alcohol (2 moles of ethylene oxide), its consumption is 0.1% to 5%, so that having, final sanitizing composition is lower than 4, the final viscosity of 000cps.
106. the alcogel shape composition of any one in the claim 95 to 105, it comprises emulsifying agent benefit humectant and softener composition or these mixture of ingredients, its consumption is extremely about 2.0 weight % of about 0.10 weight %, is lower than 4, the final viscosity of 000cps so that final sanitizing composition has.
107. the alcogel shape composition of claim 106, wherein said emulsifying agent is mended the mixture that humectant and softener composition or these mixture of ingredients comprise the pure and mild ceteareth 20 of cetearyl alcohol.
108. the alcogel shape composition of any one in the claim 95 to 107, it comprises antiseptic-germicide.
109. the alcogel shape composition of claim 108, wherein said antiseptic-germicide are consumptions at about 0.50 weight % to the chlorhexidine gluconate between about 4.0 weight %.
110. the alcogel shape composition of claim 108, wherein said antiseptic-germicide is selected from following material: the form complexed of chlorhexidine salt, iodine, iodine, chlorxylone, triclosan, Hexachlorophene, phenol, the tensio-active agent with long-chain hydrophobic group and quaternary groups, hydrogen peroxide, silver, silver salt, silver suboxide and their mixture.
111. the alcogel shape composition of any one in the claim 95 to 110, it comprises that consumption is the sanitas of about 0.01 weight % of total composition to about 5 weight %.
112. the alcogel shape composition of any one in the claim 95 to 111, its also comprise acid or alkali with the pH that regulates described composition to the pH that selects in advance, its consumption is that about 0.05 weight % of total composition is to about 0.5 weight %.
113. the composition of claim 112, wherein said acid is selected from hydrochloric acid, citric acid and phosphoric acid, and described alkali is concentrated crystal soda.
114. the alcogel shape composition of any one in the claim 95 to 113, it is stored in the uninflated sending trap, and this sending trap has and is used for therefrom providing with gel form the sending trap pump of described composition.
115. the alcogel shape composition of any one in the claim 95 to 113, it is stored in the uninflated sending trap, this sending trap has and is used for therefrom providing the sending trap pump of described sanitizing composition, and described composition comprises that consumption is the aerosol propellants of about 3 weight % of total composition to about 20 weight %.
116. the alcogel shape composition of claim 115, wherein said aerosol propellants is selected from propane, carbonic acid gas, butane, Refrigerant 12, dichloro tetrafluoro ethane, Perfluorocyclobutane, 1,1,1,2-Tetrafluoroethane, 1,1,1,2,3,3,3-heptafluoro-propane and 1,1,1,3,3,3 ,-HFC-236fa.
117. the alcogel shape composition of claim 115 or 116, it comprises corrosion inhibitor, and described corrosion inhibitor is selected from Sorbic Acid, phenylformic acid, potassium sorbate and Sodium Benzoate, and its consumption is that about 0.1 weight % of total composition is to about 5 weight %.
CN 200480035318 2003-09-29 2004-09-29 High alcohol content gel-like and foaming compositions Pending CN1886492A (en)

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CN104220042A (en) * 2012-04-30 2014-12-17 金伯利-克拉克环球有限公司 Foaming formulations including silicone-based polyurethanes
CN108026480A (en) * 2015-07-17 2018-05-11 约翰逊父子公司 Hard-surface cleaning compositions with propellant
CN108456595A (en) * 2018-03-05 2018-08-28 湖州晶合化工有限公司 A kind of cleaning agent for electronic material

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104220042A (en) * 2012-04-30 2014-12-17 金伯利-克拉克环球有限公司 Foaming formulations including silicone-based polyurethanes
CN104220042B (en) * 2012-04-30 2018-04-24 金伯利-克拉克环球有限公司 Include the effervescent preparations of siloxy group polyurethane
CN108026480A (en) * 2015-07-17 2018-05-11 约翰逊父子公司 Hard-surface cleaning compositions with propellant
CN108456595A (en) * 2018-03-05 2018-08-28 湖州晶合化工有限公司 A kind of cleaning agent for electronic material

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