CN1883412B - Laser medical equipment - Google Patents

Laser medical equipment Download PDF

Info

Publication number
CN1883412B
CN1883412B CN2005100772756A CN200510077275A CN1883412B CN 1883412 B CN1883412 B CN 1883412B CN 2005100772756 A CN2005100772756 A CN 2005100772756A CN 200510077275 A CN200510077275 A CN 200510077275A CN 1883412 B CN1883412 B CN 1883412B
Authority
CN
China
Prior art keywords
optical fiber
laser
fiber
medical equipment
equipment according
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CN2005100772756A
Other languages
Chinese (zh)
Other versions
CN1883412A (en
Inventor
熊振宏
杜少睿
姚广涛
李如旺
范馨燕
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Accu Tech Co ltd
Original Assignee
AIKE KAINENG TECHNOLOGY (BEIJING) Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by AIKE KAINENG TECHNOLOGY (BEIJING) Co Ltd filed Critical AIKE KAINENG TECHNOLOGY (BEIJING) Co Ltd
Priority to CN2005100772756A priority Critical patent/CN1883412B/en
Publication of CN1883412A publication Critical patent/CN1883412A/en
Application granted granted Critical
Publication of CN1883412B publication Critical patent/CN1883412B/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Images

Landscapes

  • Laser Surgery Devices (AREA)

Abstract

A laser medical equipment comprises at least a laser device, at least a laser output port, an optical fiber for transferring the laser and an optical fiber output end, wherein the optical fiber for transferring the laser is one group and in capable of being inserted into an endoscope simultaneously, and the number of the optical fiber for transferring the laser is corresponding to that of the optical fiber output end. The laser medical equipment is characterized in that one group of the optical fiber output end uses one of the following combination modes: two optical fibers with oblique optical end faces, namely oblique incidence optical fibers, the laser sent by the two optical fibers forming a V-shaped optical ring cut; or three optical fibers all being oblique face and oblique incidence, namely the oblique incidence optical fibers, the send laser forming a conical optical ring cut. Each optical fiber can be fixed by fusion or an optical fiber sleeve with a mechanical structure.

Description

Laser medical equipment
Technical field
The present invention relates to a kind of laser medical equipment, relate in particular to a kind of many optical fiber ring of light and cut surgical apparatus.
Background technology
Laser is the light beam of being launched by the working-laser material generation stimulated radiation that is in the population inversion state that energy height is concentrated, directivity is extremely strong, monochromaticity is good, laser therapy aparatus is heat effect and a controllability of utilizing laser, it is acted on tissue, shine, medical procedure such as cutting, ablation to be to finish the optical, mechanical and electronic integration equipment of treatment.Figure 15 discloses a kind of main structure form of laser therapy aparatus: constitute basic laser instrument by reflecting mirror 1 ', laser pump cavity 2 ', pumping lamp 3 ', laser crystal bar 4 ', outgoing mirror 5 ', one 45 degree spectroscopes 6 ' are set on laser instrument ejaculation light path, on perpendicular direction, be provided with indication light source 7 ', again by fiber coupler 8 ', output optical fibre 9 ', can be with the light-emitting window of optic path to operation cutter head 10 ', treat or surgical cut for the doctor, wherein pump supply source 11 ' provides power supply for pumping lamp 3 '.It is to penetrate light by basic laser instrument to pass through fiber coupler, output optical fibre again with the light-emitting window of optic path to the operation cutter head, treats or surgical cut for the doctor.
The laser instrument of existing laser therapy aparatus generally is divided into two kinds of working forms: a kind of is continuous wave laser, and the pumping lamp of this laser instrument is only successive, sends continuous laser, acts on tissue; Another kind is a pulse laser, the only pulse of the pumping lamp of this laser instrument, thereby send the laser of pulsed, Laser emission is spaced, be 200us as pulse width.
Be used for therapeutic medical optical-fiber laser surgical apparatus at present, mainly be used for realizing that LASER HEAT is melted, operation such as vaporization and excision.In these operations, need be by medical apparatus---endoscope, utilize body surface nature duct or otch that endoscope is imported human body earlier, can check esophagus, gastrointestinal, trachea, lung, bladder, joint, even tissue such as brain.Miniature endoscope also can import unapproachable places such as bile duct, ductus pancreaticus.During operation, the optical fiber of laser operation equipment can arrive therapentic part by the irrigation channel of endoscope.The doctor can make optical fiber accurately required therapentic part be treated by rotating the conduit of endoscope.
The green laser PV system of Laserscrope company, employing be PVP technology (selective light prostate vaporization art), use the side launching fiber to tissue vaporization.The laser shovel of DORNIER (many Neils) is to adopt prostate laser contact gasification, and many Neils laser spader has thin thin special termination, and to all the winds move the termination, thereby with the high heat energy vaporization tissue of being cut.If organizing that all need excise all will be safely by the method for vaporization, its shortcoming is that operating time is long, and the doctor of most skilled operation TURP methods is reluctant to adopt such laser vaporization art.Simultaneously in medical diagnosis, need cut tissue (as tumor, hypertrophy body of gland) is carried out pathological study, tissue biopsy etc., yet do not existed, can not satisfy the requirement of medical diagnosis by vaporization operation back related organization.
In the holmium Lasar prostate enucleation of section doctor people company, by the optical-fiber laser surgical apparatus, by cystoscope with a direct projection optic fibre end towards the place ahead, vertically cut two ribs after, reuse optical fiber excises body of gland from the bottom, as Figure 16.Again the body of gland that downcuts is pushed intravesical,, discharge with organizing pulverizer that the gland tissue that downcuts is pulverized.In the enucleation because optical fiber and gland tissue bottom is all invisible, when the excision gland tissue, be difficult to the accurately direction and the degree of depth of control laser, in operation, be easy to cause the perforation of body of gland peplos, dangerous in the operation of intravesical pulverizing body of gland simultaneously, and also the inorganization section is for pathological study.
According to existing technology status, have only 80W in the maximum average power of the specified transmission of next root optical fiber of air cooled situation, even under 80W, also be easy to cause the damage of optical fiber, as fractureing from the optical fiber root.
The patented product ScatterFree side emission optical fiber of Laser Peripherals company, its end are one and are designed to angled probe, can realize accurate powerful laser beam side direction transmission, satisfy complicated more clinical practice.
In sum, everybody all actively be devoted to the structure of laser therapy aparatus and purposes continuous improvement, continually develop.But up to the present, no matter be that archetype or follow-on optical-fiber laser surgical apparatus that is used for cutting operation are single laser instrument and join single fiber monochromatic light road light-emitting window, there are some shortcoming parts: when being used for cutting operation, stroke length causes operating time length, cuts an accurate rate variance, also just increased the time and the risk of operation, the time that allows patient pull the devil by the tail is also long.
Summary of the invention
The purpose of this invention is to provide a kind of laser medical equipment, utilize it to carry out cutting operation and can directly cut out tissue, operation safety is convenient, and the time is short.
For achieving the above object, the present invention takes following design: a kind of laser medical equipment, the optical fiber and the fiber-optic output that comprise laser instrument, laser output mouth, transmission laser, the quantity of described laser instrument is at least one or described laser output mouth and is at least one, the optical fiber of described transmission laser is one group and can inserts endoscope simultaneously that the optical fiber of described transmission laser is corresponding with the quantity of fiber-optic output; Described one group of fiber-optic output is one of following compound mode: two optical fiber, and fiber end face is oblique, i.e. oblique fire optical fiber, the laser that these two optical fiber send constitute V-arrangement ring of light otch; Or three optical fiber all are that the inclined-plane is tiltedly launched, i.e. oblique fire optical fiber, and the laser that sends constitutes conical ring of light otch.
Described laser medical equipment can have a laser instrument, and one group of light path of its output has 2 the tunnel at least.
It is the optical fiber of twin-core at least that described one group of optical fiber is one.
Described one group of optical fiber is the optical fiber more than two, and this group optical fiber is combined by single core and single core or multicore and multicore, single core and multicore.
Described one group of optical fiber is direct projection optical fiber or is oblique fire optical fiber or their combination.
Described one group of optical fiber is two oblique fire optical fiber, two laser formation V-arrangement ring of light cutting knifes that optical fiber sends.
Described one group of optical fiber is three oblique fire optical fiber, three laser formation taper ring of light cutting knifes that optical fiber sends.
Described each optical fiber can be fixed by the optical fiber cartridge clip of welding or frame for movement.
Advantage of the present invention is:
1, result of use is good: utilize this laser operation equipment to carry out cutting operation, safe ready and time are short;
2, service efficiency height: use multifiber to transmit laser simultaneously, can increase exponentially the laser energy of fiber-optic transfer.
3, the scope of application is wide: the flexible combination utilization of laser instrument and number of fibers makes its output energy, cutting profile, treatment mechanism all can satisfy multiple requirement.
4, can be beneficial to and carry out biopsy in a organized way: after using the optical-fiber laser cutter with cutting tissue, can take out human body and carry out pathological study outward.
Description of drawings
Fig. 1 is a structural representation of the present invention
Fig. 2 is one embodiment of the invention structural representation
Fig. 3 is another embodiment of the present invention structural representation
Fig. 4 is further embodiment of this invention structural representation
Fig. 5 is yet another embodiment of the invention structural representation
Fig. 6 is the protection segment structure sketch map (section) of oblique fire optic fibre end
Fig. 7 is the angle sketch map between fiber end face normal and the optical axis
Fig. 8 realizes side emission one embodiment sketch map for optical fiber
Fig. 9-A is that optical fiber is realized the another embodiment sketch map of side emission
Fig. 9-B is that the light path of Fig. 9-A illustrated embodiment is moved towards sketch map (direction of arrow is the light emission direction)
Figure 10 is that the straight hair of a twin-core fiber is penetrated sketch map
The operation sketch map that Figure 11 penetrates for two optical fiber straight hairs
Figure 12 is the operation sketch map of two optical fiber ring of light cutting knifes
Figure 13 is the operation sketch map of the conical ring of light cutting knife of three optical fiber formations
Figure 14 is the labelling sketch map on the optical fiber
Figure 15 is a laser therapy aparatus principle of compositionality block diagram in the prior art
Figure 16 uses simple optical fiber operation sketch map in the prior art
Below in conjunction with the accompanying drawing and the specific embodiment the present invention is described in further detail:
The specific embodiment
As shown in Figure 1, laser medical equipment of the present invention comprises the optical fiber 300 and the fiber-optic output of laser instrument 100, laser output mouth 200, transmission laser, design point of the present invention is: described laser medical equipment has a laser instrument at least, has one group can insert the optical fiber of endoscope and the laser output mouth and the fiber-optic output of respective amount simultaneously.
Laser instrument number and optical fiber way can have multiple compound mode except that example shown in Figure 1 in the laser medical equipment of the present invention, Fig. 2, Fig. 3, Fig. 4 and Fig. 5 shown in also four kinds of conventional embodiment: laser therapy aparatus has a laser instrument among Fig. 2, a twin-core fiber output.In addition, laser therapy aparatus also can be that a laser instrument is arranged, a multi-core fiber output; Fig. 3 is that laser therapy aparatus has a laser instrument, two optical fiber outputs; Fig. 4 is that laser therapy aparatus has a laser instrument, three optical fiber outputs; Fig. 5 is that laser therapy aparatus has two laser instrument, two optical fiber outputs.
Wherein, many combinations are arranged also when adopting two laser instrument, as: two laser instrument are two laser instrument that output characteristic is identical with parameter; Two laser instrument are two laser instrument that output characteristic is different with parameter; Two laser instrument are continuous wave laser; Two one in laser instrument are successive, and one is pulse; Two laser instrument are pulse laser, wherein, the operating frequency of two pulse lasers is identical or different, and pulse width can be identical or different, phase intervals between two laser pulses can be regulated, and it can realize (prior art can realize) by computer control at interval.When adopting three, four so that during n laser instrument, also can be used in combination by above-mentioned logical relation.
Fiber-optic output also can have a variety of compound modes in the laser medical equipment of the present invention.One group of optical fiber is at least the optical fiber of one two core or multicore; One group of optical fiber is two when above, can be that the combination of single core and single core, multicore and multicore or single core and multicore is used.When adopting multifiber, optic fibre characteristic parameter (as optical fiber core diameter, numerical aperture, material etc.) can be all identical or all inequality separately or part is identical and different.Fiber end face can be flat or oblique.
The optical fiber (being that fiber end face is oblique) of angle is arranged between the optical axis for the normal direction of end face and optical fiber, be not damaged in order to protect optical fiber, the present invention has added fiber optic protection section 401 in the fiber-optic output tip, as shown in Figure 6.It is that the covering of optical fiber is handled, and the covering system on limit, tip is flat, plays protective effect to optical fiber 300 fiber cores with this structure.
Realize side emission for optical fiber, following two examples of implementation are arranged: a kind of is that fiber end face tilts to realize side emission, Fig. 7 is the angle sketch map between fiber end face normal and the optical axis, between the optical axis for the normal direction of fiber end face and optical fiber angle is arranged
Figure GSB00000465424500051
Optical fiber, its maximum angle is
Figure GSB00000465424500052
We with in water (because of the environment of operation is in blood) be the angle that example is calculated maximum:
Figure GSB00000465424500053
Wherein, n WaterBe the refractive index of water, n QuartzyRefractive index for quartz. the angle between the normal direction of fiber end face and the optical axis of optical fiber is as long as satisfy Get final product.
Be multifiber and be the optical fiber that angle is arranged between the optical axis of the normal direction of fiber end face and optical fiber that for one group the laser angular range that the laser that optical fiber sends constitutes can be 0 °~180 °.
The optical fiber of another kind of realization side emission is that the plating reflectance coating is worn into a kind of angle with fiber end face on angled fiber end face, such as the angular range between the optical axis of the normal direction of fiber end face and optical fiber probably between 30 ° to 150 °, as get 45 °, plating high-reflecting film layer 402 on the end face, as λ 0/4 film be, then the Laser emission direction is 90 °, also can realize side emission, referring to Fig. 8.
Also can adopt the patented product ScatterFree side emission optical fiber of Laser Peripherals company, it is that tip designs with silica fibre becomes angled probe, in the optical fiber connector welding quartz socket tube 403 is arranged, exist simultaneously an air chamber 500 to be beneficial to the emission of optical fiber between the end of optical fiber and quartz socket tube (referring to Fig. 9-A, Fig. 9-B).
During application, for one group be many optical fiber, all optical fiber delivery outlet end faces can be all be the plane or all tool with the angle inclined-plane, but also each tool different angles inclined-plane.
For the multifiber group, the distance L scope between adjacent two fiber cores is: 0≤L≤D-d, and wherein, D is endoscope's trans D, d is a fibre diameter.For multifiber or difform endoscope, and the like, as long as satisfy optical fiber all within endoscope.
Figure 10, Figure 11, Figure 12 and Figure 13 are four kinds of exemplifying embodiments of fiber-optic output compound mode: a kind of is that one two core fibre is realized the emission of two-way optical fiber, and fiber end face is flat, as Figure 10.Second kind is two-way optical fiber, and fiber end face is flat, can be used for straight hair and penetrates optical fiber and play urinary system calculus operation, as Figure 11.These two kinds of optical fiber combination modes are applicable in the big rubble operation of power requirement.The third is a two-way optical fiber, fiber end face is oblique, two laser formation V-arrangement ring of light otch that optical fiber sends, as Figure 12, can be used for the operation of two optical fiber V shape ring of light cutting knifes, downcut certain depth organizationally with the light circular cutter after, continue the edge and laterally cut out two traverse furrows, upwards lift then, get final product resection organization.Also having a kind of is that three optical fiber all are side emissions, and the laser that sends constitutes conical ring of light otch, as Figure 13, downcut certain depth organizationally with the light circular cutter after, rotate 60 ° after, upwards lift, get final product resection organization.
For the V-arrangement ring of light cutting knife that two optical fiber are formed, optical fiber is side emission laser, and rising angle is less than 62.46 °.According to different wavelength of laser therapy apparatus and different medical applications, can select suitable laser angle.
The laser angular range that the laser that the V-arrangement ring of light cutting knife of forming for two optical fiber, two optical fiber send forms is 0 °~180 °, and this is mainly on the penetration depth of optical maser wavelength and the tissue that will excise is big or small decides.
For the V-arrangement ring of light cutting knife that two optical fiber are formed, after side direction optical fiber emission laser direction and laser angle had been decided, the direction of V-arrangement ring of light cutting knife was also just fixed.
For two optical fiber V shape ring of light cutting knifes that two optical fiber constitute, can select welding or frame for movement to fix between the optical fiber.When adopting frame for movement fixedly, have to be in harmonious proportion non-adjustable two kinds of fixation clamps.Optical fiber fixation clamp 301 referring to shown in Figure 12 has bearing mark 302 on the optical fiber fixation clamp.
For the taper ring of light cutting knife that three optical fiber are formed, optical fiber is side emission laser, and the laser of selecting suitable rising angle that three optical fiber are sent constitutes taper ring of light cutting knife, can satisfy the different application of medical treatment.
For the taper ring of light cutting knife that three optical fiber are formed, three optical fiber are mutually symmetrical.The laser angular range that the laser that two optical fiber sends forms is 0 °~180 °, and this is mainly on the penetration depth of optical maser wavelength and the tissue that will excise is big or small decides.
For the optical fiber group more than two, can select welding or frame for movement to fix between the optical fiber.When adopting frame for movement fixedly, have to be in harmonious proportion non-adjustable two kinds of fixation clamps.As the non-adjustable optical fiber fixation clamp 301,303 among Figure 12,13.
For the optical fiber group more than two, the orientation of optical fiber is made marks, as among Figure 12 being the labelling of on optical fiber fixation clamp 301, doing 302.Be the labelling of on optical fiber, doing shown in Figure 14, shown in optical fiber be the side emission optical fiber of end slope.
In addition, when using the above optical fiber of two or two, on the optical fiber light direction labelling can be arranged, as Figure 14.
The fiber-optic output compound mode that among the present invention these are different to the requirement of laser power and different medical operatings, can cooperate different laser therapy aparatuses to be used in combination according to the doctor.For unit join multi-pass optical fiber, multimachine is joined multi-pass (no matter being quantity equity or not reciprocity) optical fiber, all can realize by existing routine techniques, give unnecessary details no longer one by one herein.

Claims (10)

1. laser medical equipment, the optical fiber and the fiber-optic output that comprise laser instrument, laser output mouth, transmission laser, the quantity of described laser instrument is at least one, the optical fiber of described transmission laser is one group and can inserts endoscope simultaneously that the optical fiber of described transmission laser is corresponding with the quantity of fiber-optic output; It is characterized in that: described one group of fiber-optic output is one of following compound mode: two optical fiber, and fiber end face is oblique, i.e. oblique fire optical fiber, the laser that these two optical fiber send constitute V-arrangement ring of light otch; Or three optical fiber all are that the inclined-plane is tiltedly launched, i.e. oblique fire optical fiber, and the laser that sends constitutes conical ring of light otch.
2. laser medical equipment according to claim 1 is characterized in that: angle ф≤62.46 between the normal direction of its end face of output end face of described oblique fire optical fiber and the optical axis of optical fiber °.
3. laser medical equipment according to claim 2 is characterized in that: described oblique fire optical fiber output end face tilts 30 °~150 °, plating high-reflecting film layer on the end face.
4. laser medical equipment according to claim 2 is characterized in that: described oblique fire optical fiber output end face tilts, and outfan has quartz socket tube, and places a kind of gas.
5. laser medical equipment according to claim 2 is characterized in that: described one group of oblique fire optical fiber is formed by the optical fiber combination of all equal tool of output end face with angle inclined-plane or each tool different angles inclined-plane.
6. laser medical equipment according to claim 2 is characterized in that: there is the protection section tip, described oblique fire fiber-optic output inclined-plane.
7. laser medical equipment according to claim 1 is characterized in that: have bearing mark on the described optical fiber.
8. laser medical equipment according to claim 1 is characterized in that: each optical fiber interfixes by welding in described one group of optical fiber.
9. laser medical equipment according to claim 1 is characterized in that: each optical fiber is fixed by frame for movement in described one group of optical fiber, and described frame for movement is adjustable or non-adjustable two kinds of fixation clamps.
10. laser medical equipment according to claim 9 is characterized in that: have bearing mark on the described optical fiber fixation clamp.
CN2005100772756A 2005-06-21 2005-06-21 Laser medical equipment Expired - Fee Related CN1883412B (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN2005100772756A CN1883412B (en) 2005-06-21 2005-06-21 Laser medical equipment

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN2005100772756A CN1883412B (en) 2005-06-21 2005-06-21 Laser medical equipment

Publications (2)

Publication Number Publication Date
CN1883412A CN1883412A (en) 2006-12-27
CN1883412B true CN1883412B (en) 2011-06-22

Family

ID=37581805

Family Applications (1)

Application Number Title Priority Date Filing Date
CN2005100772756A Expired - Fee Related CN1883412B (en) 2005-06-21 2005-06-21 Laser medical equipment

Country Status (1)

Country Link
CN (1) CN1883412B (en)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9661986B2 (en) * 2014-07-24 2017-05-30 Z Square Ltd. Multicore fiber endoscopes
CN104905889B (en) * 2015-06-06 2017-01-25 四川航天世都制导有限公司 Double-optical-path water and gas spraying YAG laser treatment system
WO2018054800A1 (en) * 2016-09-21 2018-03-29 Koninklijke Philips N.V. A cutting assembly for a hair cutting device
CN109567933B (en) * 2018-12-07 2021-08-06 中聚科技股份有限公司 Double-optical fiber laser treatment device
CN109567931A (en) * 2018-12-07 2019-04-05 中聚科技股份有限公司 A kind of replaceable laser probe and device for laser therapy of the end with optothermal material
CN111067620A (en) * 2019-12-30 2020-04-28 天津欧泰激光科技有限公司 Multi-direction divergent irradiation laser medical optical fiber light guide system
CN111146676B (en) * 2019-12-30 2021-07-06 武汉戴美激光科技有限公司 Method and equipment for generating multi-wavelength pulse laser
CN112569477B (en) * 2020-12-04 2022-07-29 锐可医疗科技(上海)有限公司 Laser therapeutic apparatus and storage medium
CN114406499B (en) * 2022-02-24 2024-12-17 桂林市啄木鸟医疗器械有限公司 Laser cutting device and laser cutting method

Also Published As

Publication number Publication date
CN1883412A (en) 2006-12-27

Similar Documents

Publication Publication Date Title
US4760840A (en) Endoscopic laser instrument
Bach et al. Laser treatment of benign prostatic obstruction: basics and physical differences
US7909817B2 (en) Lateral laser fiber for high average power and peak pulse energy
US4852567A (en) Laser tipped catheter
ES2899977T3 (en) Laser treatment device with emission tip for non-contact use
US20060078265A1 (en) Device and method for delivery of long wavelength laser energy to a tissue site
US20080051770A1 (en) Multiple Target Laser Probe
EP3270810B1 (en) Side-fire laser fiber having a molded reflective surface
CN1883412B (en) Laser medical equipment
CN102281917A (en) Photothermal treatment of soft tissues
KR20120120112A (en) Twister fiber optic systems and their use in medical applications
US12078852B2 (en) Optical fiber device for laser thermal ablation and thermal therapy
KR20230007814A (en) Laser device for thyroid cancer treatment
CN201404290Y (en) One-way lateral emitting light laser fiber structure
CN2824860Y (en) Mini Infrared Laser Hair Remover
US6699236B1 (en) Cutting blade for surgical instrument
US20080147150A1 (en) Medical laser device
US20080287933A1 (en) Multifiber Instrument for Contact Laser Surgery
US20240390066A1 (en) Optical fiber device and method for thermal therapy and laser thermal ablation treatments
CN119257702B (en) Light-transmitting percutaneous optical fiber puncture device
CN211213485U (en) Laser side-emitting optical fiber for minimally invasive surgery
Bülow Present status of endoscopic laser techniques in urology
Russo et al. Axially-and side-radiating optical fibres for medical applications
DeRowe et al. Comparison of CO2 laser effects on nasal mucosa tissue using either clad or unclad silver halide optical fiber delivery system
CN119257703A (en) An integral luminous percutaneous optical fiber puncture device

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
C14 Grant of patent or utility model
GR01 Patent grant
PE01 Entry into force of the registration of the contract for pledge of patent right

Denomination of invention: Laser medical equipment

Effective date of registration: 20120905

Granted publication date: 20110622

Pledgee: Zhongguancun Beijing science and technology Company limited by guarantee

Pledgor: Aike Kaineng Technology (Beijing) Co.,Ltd.

Registration number: 2012990000498

C56 Change in the name or address of the patentee

Owner name: ACCU-TECH (BEIJING) CO., LTD.

Free format text: FORMER NAME: AIKE KAINENG TECHNOLOGY (BEIJING) CO., LTD.

CP01 Change in the name or title of a patent holder

Address after: 100102 Beijing City, Chaoyang District Wangjing new industrial zone in Lize Park building 106 314A

Patentee after: ACCU-TECH CO.,LTD.

Address before: 100102 Beijing City, Chaoyang District Wangjing new industrial zone in Lize Park building 106 314A

Patentee before: Aike Kaineng Technology (Beijing) Co.,Ltd.

PLDC Enforcement, change and cancellation of contracts on pledge of patent right or utility model
PM01 Change of the registration of the contract for pledge of patent right

Change date: 20131227

Registration number: 2012990000498

Pledgee after: Zhongguancun Beijing technology financing Company limited by guarantee

Pledgee before: Zhongguancun Beijing science and technology Company limited by guarantee

Change date: 20131227

Registration number: 2012990000498

Pledgor after: ACCU-TECH CO.,LTD.

Pledgor before: Aike Kaineng Technology (Beijing) Co.,Ltd.

PC01 Cancellation of the registration of the contract for pledge of patent right

Date of cancellation: 20131227

Granted publication date: 20110622

Pledgee: Zhongguancun Beijing technology financing Company limited by guarantee

Pledgor: Aike Kaineng Technology (Beijing) Co.,Ltd.

Registration number: 2012990000498

PLDC Enforcement, change and cancellation of contracts on pledge of patent right or utility model
PM01 Change of the registration of the contract for pledge of patent right

Change date: 20131227

Registration number: 2012990000498

Pledgee after: Zhongguancun Beijing technology financing Company limited by guarantee

Pledgee before: Zhongguancun Beijing science and technology Company limited by guarantee

C56 Change in the name or address of the patentee
CP02 Change in the address of a patent holder

Address after: 100015, room 503, building M8, building 1, Jiuxianqiao East Road, Chaoyang District, Beijing,

Patentee after: ACCU-TECH CO.,LTD.

Address before: 100102 Beijing City, Chaoyang District Wangjing new industrial zone in Lize Park building 106 314A

Patentee before: ACCU-TECH CO.,LTD.

CF01 Termination of patent right due to non-payment of annual fee
CF01 Termination of patent right due to non-payment of annual fee

Granted publication date: 20110622