CN1876104A

CN1876104A - Chinese medicinal liquor for treating astrophic gastritis and preparation method thereof

Info

Publication number: CN1876104A
Application number: CNA2006100176945A
Authority: CN
Inventors: 张艾明; 周中堂
Original assignee: Individual
Current assignee: Individual
Priority date: 2006-04-25
Filing date: 2006-04-25
Publication date: 2006-12-13
Anticipated expiration: 2026-04-25
Also published as: CN100593416C

Abstract

The invention relates to a Chinese oral liquid preparation for treating gastritis and process for preparation, wherein the raw materials of the oral liquid include green tangerine orange peel 5-7 parts, banksia rose 8-10 parts, fresh hen egg 20-30 parts, beach silvertop root 8-15 parts, elephantopus 1-5 parts, ophiopogon root 10-20 parts, dried rehmannia root 10-30 parts and vinegar 500 parts.

Description

The Chinese medicine oral liquid and the preparation method of treatment atrophic gastritis

(1) technical field

The present invention relates to a kind of medicine for the treatment of gastropathy, especially treat the Chinese medicine oral liquid of atrophic gastritis and control Preparation Method.

(2) background technology

Atrophic gastritis is a kind of very common digestive tract disease, is main pathological change with the nonspecific inflammation of gastric mucosa, according to the Histological change of gastric mucosa.Can the branch shallow, atrophic, plumpness etc. can cause chronic atrophic gastritis.With advancing age, the incidence rate of primary disease also increases thereupon, and lesion degree is also heavy more, so there is the people to think that chronic atrophic gastritis is the degeneration of person in middle and old age's gastric mucosa, is a kind of " reason in half a lifetime " phenomenon.The sickness rate of gastric cancer district occurred frequently chronic atrophic gastritis is than the low district's height of sending out.

The traditional Chinese medical science is thought the cause of disease of chronic atrophic gastritis, and not outer eating and drinking without temperance is killd the damaging the spleen and stomach state; Or invade in the exopathogen, undermine taste; Or anxiety and rage, the liver failing to maintain the normal flow of QI, perverse and unreasonable manner is violated stomach; And innate deficiency, weakness of the spleen and stomach etc.But in close relations with " spleen ", " liver ", " kidney ", pathogenic characteristic is a deficiency complicated with excess at " stomach " in its sick position.

Clinical manifestation: be mainly that loss of appetite, epigastrium are vexed to expand, pain, heating installation are frequent, pantothenic acid, loss of appetite, become thin, diarrhoea etc., upper gastrointestinal hemorrhage can take place, becomes thin in a few patients, anemia, onychorrhexis, glossitis or atrophy of tongue papillae etc.

At present the doctor trained in Western medicine method of treatment atrophic gastritis is as (1) general treatment: chronic atrophic gastritis patient, no matter its cause of disease how, all should give up smoking and give up alcohol, avoid using the medicine of infringement gastric mucosa such as aspirin, indometacin, erythromycin etc., the suitable rule of diet, avoid overheated, over-salty and maror, the chronic mouth of active treatment, nose, pharyngeal infection focus.(2) weak acid treatment: the patient can take rice vinegar or 10% dilute hydrochloric acid in right amount, takes the pepsin mixture simultaneously and also can select polyzyme tablets (DPP) or pancreatin tablets treatment for use, to improve indigestion symptom.(3) anti-helicobacter pylori treatment: during chronic atrophic gastritis, gastric acid reduces or lacks, and it is very high that gastric antibacterial evil life, especially helicobacter pylori detect positive rate.Use antibiotics, the doing well,improving that promotes chronic atrophic gastritis is had certain curative effect.The Therapeutic Method that is usually used in removing helicobacter pylori is: and tripotassium two rafter complexation bismuths (TDB, De, NOL); The Amoxcillin cellulose capsule; Furazolidone (furazolidone).The medicative medicine of helicobacter pylori also had gentamycin, berberine, metronidazole, tetracycline, norfloxacin etc.(4) suppress bile reflux and improve gastric motility.(5) mucosa nutritive: gefarnate can increase gastric mucosa to be upgraded, and improves the cell regeneration ability, strengthens the resistivity of gastric mucosa to gastric acid, reaches the effect of protection gastric mucosa.(6) pentagastrin and hormone.(7) other symptomatic treatments: comprise relieving spasm to stop pain, emesis, aid digestion, anxiety, the anemia etc. of improving.(8) operative treatment.The course of treatment of western medical treatment atrophic gastritis is long as can be seen from above-mentioned, the medical expense height, and the patient is difficult to adhere to treatment.

The long spirit of Chinese traditional treatment use stomach as usual, stomach Shu Kang, Radix Sarcococcae Ruscifoliae (Herba Sarcoclccae Ruscifoliae), pain relieving convulsion, gastropathy one obedient spirit etc. are for oral administration, the medicine of external, patients with gastric disease there is certain curative effect, but also there are some side effect, Most patients take with external after, can damage stomach, liver, kidney etc., and the course of treatment is long, and the medical expense height makes the patient be difficult to accept.

(3) summary of the invention

The objective of the invention is to overcome said medicine some defectives in treatment, a kind of curative effect height, short treating period are provided, have no side effect, medical expense is low, treatment method is simple, do not answer the Chinese medicine oral liquid and the preparation method of the treatment atrophic gastritis of method after more.

To achieve the above object, the present invention is according to following method.

This oral liquid be with Pericarpium Citri Reticulatae Viride (life) 5-7 part, the Radix Aucklandiae (life) 8-10 part, fresh hen egg (life) 20-30 part, Radix Glehniae (life) 8-15 part, Radix Gentianae 1-5 part, Radix Ophiopogonis 10-20 part, the Radix Rehmanniae (life) 10-30 part, vinegar be raw material for 500 parts.And on the basis of above-mentioned consumption, can also add Fructus Chaenomelis 15-20 part, Radix Paeoniae Alba 10-20 part.

5 parts on the preferred Pericarpium Citri Reticulatae Viride of described each several part (life), 8 parts of the Radix Aucklandiae (life), 18 parts of Fructus Chaenomeliss, 25 parts of fresh hen eggs (life), 15 parts of the Radix Paeoniae Albas, 15 parts of Radix Glehniaes (life), 2 parts of Radix Gentianaes, 18 parts of Radix Ophiopogonis, 20 parts in the Radix Rehmanniae (life), 500 parts of vinegar.

Concocting method is as described below:

The first step fries Radix Ophiopogonis, Fructus Chaenomelis to little Huang, and Radix Gentianae stirs with Fel Sus domestica, and the Radix Paeoniae Alba is fried to little Huang with wine;

Second step is Pericarpium Citri Reticulatae Viride (life), the Radix Aucklandiae (life), and Radix Glehniae (life), the Radix Rehmanniae (life) is ground into Powdered and to put into container for stirring even;

The 3rd step put into gained powdery medicine in Radix Ophiopogonis, Fructus Chaenomelis, Radix Gentianae, the Radix Paeoniae Alba and the step 2 of processing in the step 1 to pull out after vinegar liquid immersion a couple of days with gauze parcel and removes slag;

The 4th step stirred into a paste egg;

The 5th step packed vinegar liquid in the container into and added the above-mentioned pasty state egg that stirred into and gets final product.

The present invention has passed through the clinical of nearly thousand examples, has obtained better curative effect.Through repeated screening, the length of rich many families, its superior part is:

1. than tablet commonly used or powder, be easier to absorb;

2. saved the loaded down with trivial details program that Chinese herbal medicine need be fried in shallow oil, boil, opened the container of powder charge thing and can directly drink;

3. owing to the egg composition is arranged, therefore except that medicinal effects, also has the effect of health care, nutrition interior;

Curative effect height, short treating period, have no side effect;

5. medical expense is low, and treatment method is simple, does not recur after healing.

6. this oral liquid is also effective to general gastropathy such as chronic gastritis

Atrophic gastritis belongs to " gastric abscess " category in the Chinese medicine, its pathogenic factor is not outer to be that eating and drinking without temperance injures taste, the troubled thoughts impairing the liver causes the liver failing to maintain the normal flow of QI, injuring taste or obstinate disease causes weakness of the spleen and stomach and causes, its pathogenesis is the deficiency of vital energy, the stagnation of QI, cold coagulation, blood stasis, intends the method for blood circulation promoting regulates qi, warming middle-JIAO for easing the stomach in the treatment.Wherein used Pericarpium Citri Reticulatae Viride, the dispelling the stagnated QI removing food stagnancy; The Radix Aucklandiae, promoting the circulation of QI to relieve pain; Fructus Chaenomelis, suppressing the hyperactive liver, stomach function regulating; Fresh hen egg, nourishing healthy; The Radix Paeoniae Alba, nourishing blood to suppress the hyperactive liver; Radix Glehniae, YIN nourishing and the production of body fluid promoting; Radix Gentianae, is good for the stomach at eliminating pathogen in the liver gallbladder fire; Radix Ophiopogonis, lung heat clearing. nourish heart; The Radix Rehmanniae, clearing away heat and cooling blood; Mature vinegar, invigorating the stomach and promoting digestion.

To the clinical practice of 960 routine atrophic gastritis, obtained better curative effect through in the past few years.Details are as follows for relevant clinical treatment situation:

Patient source: general hospital out-patient and professional out-patient.

Case history is selected: accept 960 altogether for medical treatment, wherein the male is 688,272 of women.

Therapeutic Method: the patient Su of elder generation mouth. remove foreign body in the mouth, drank twice in one day: in one glass on an empty stomach of morning (ten grams), before the sleep in evening (ten restrain), one glass on an empty stomach of morning (20 gram) after three days is before the sleep in evening (20 restrain).Take effect for three times, one month complete.

Efficacy evaluation: recovery from illness: clinical subjective symptoms disappears or basic the disappearance, and gastroscopy gastric mucosa form recovers normal substantially or near normal, the pathologic finding atrophic gastritis changes over shallow phenotype gastritis, atypical hyperplasia and intestinal epithelial metaplasia and disappears; Take a turn for the better: clinical subjective symptoms is alleviated, and gastroscopy gastric mucosa inflammation alleviates, and pathologic finding atrophic gastritis, atypical hyperplasia and intestinal epithelial metaplasia transfer moderate to by severe or transferred to slightly by moderate; Invalid: clinical subjective symptoms does not have obvious change, and gastroscopy pathology is checked the gastric mucosa no change.

Among the therapeutic outcome 960 routine patients, cure 864 examples and account for 90%, 52 examples that take a turn for the better account for 5.41%, and invalid 44 examples account for 4.58%, and total effective rate is 95.41%.

(5) specific embodiment

The present invention chooses 5 parts on Pericarpium Citri Reticulatae Viride (life), 8 parts of the Radix Aucklandiae (life), 18 parts of Fructus Chaenomeliss, 25 parts of fresh hen eggs (life), 15 parts of the Radix Paeoniae Albas, 15 parts of Radix Glehniaes (life), 22 parts of Radix Gentianaes, 15 parts of Radix Ophiopogonis, 20 parts in the Radix Rehmanniae (life), 500 parts of vinegar.

The 3rd step put into vinegar liquid with the Powdered thing in Radix Ophiopogonis, Fructus Chaenomelis, Radix Gentianae, the Radix Paeoniae Alba and the step 2 of having processed in the step 1 with the gauze parcel and soaked seven days, pulled out after seven days and removed slag;

The 4th step stirred into a paste egg;

The 5th step packed vinegar liquid to add in the container into and has become the pasty state egg to get final product.

Claims

1. the Chinese medicine oral liquid and the preparation method of treatment atrophic gastritis, it is characterized in that oral liquid be with Pericarpium Citri Reticulatae Viride (life) 5-7 part, the Radix Aucklandiae (life) 8-10 part, fresh hen egg (life) 20-30 part, Radix Glehniae (life) 8-15 part, Radix Gentianae 1-5 part, Radix Ophiopogonis 10-20 part, the Radix Rehmanniae (life) 10-30 part, vinegar be raw material for 500 parts;

Concocting method is as described below:

The first step will be fried to little Huang Radix Ophiopogonis, and Radix Gentianae stirs with Fel Sus domestica;

The 3rd step put into gained powdery medicine in Radix Ophiopogonis, Radix Gentianae and the step 2 of processing in the step 1 to pull out after vinegar liquid immersion a couple of days with gauze parcel and removes slag;

The 4th step stirred into a paste egg;

2. the Chinese medicine oral liquid of treatment atrophic gastritis as claimed in claim 1 and preparation method is characterized in that can also adding Fructus Chaenomelis 15-20 part, Radix Paeoniae Alba 10-20 part on the basis of above-mentioned consumption;

Concocting method is as described below:

The 4th step stirred into a paste egg;

3. the Chinese medicine oral liquid of treatment atrophic gastritis according to claim 1 and 2 and preparation method is characterized in that: 5 parts on the preferred Pericarpium Citri Reticulatae Viride of described each several part raw material (life), 8 parts of the Radix Aucklandiae (life), 18 parts of Fructus Chaenomeliss, 25 parts of fresh hen eggs (life), 15 parts of the Radix Paeoniae Albas, 15 parts of Radix Glehniaes (life), 2 parts of Radix Gentianaes, 18 parts of Radix Ophiopogonis, 20 parts in the Radix Rehmanniae (life), 500 parts of vinegar.