CN1842297A - System and method for polyp visualization - Google Patents
System and method for polyp visualization Download PDFInfo
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Abstract
A system and method for determining a location and a direction for viewing a protrusion, comprising: casting a plurality of rays in an outward direction from a point, wherein the point is inside a protrusion (215); selecting at least one of the plurality of rays for determining a location and a direction for viewing the protrusion (220); and determining the location and the direction for viewing the protrusion using the selected at least one of the plurality of rays (225).
Description
The cross reference of related application
The application requires the U.S. Provisional Application No.60/482 of submission on June 25th, 2003,581 rights and interests, and the copy of this provisional application is hereby incorporated by.
Background of invention
1. technical field
The three-dimensional (3D) that the present invention relates to medical image is developed (visualization), and especially relate to be used for determining to observe bulge at medical image, such as the position of polyp of colon and the system and method for direction.
2. the discussion of correlation technique
In the medical imaging field, for the purpose of screening (screen) and evaluation health, developed various systems, be used for the various anatomical structures of individuality are produced medical images.These imaging systems for example comprise computerized tomography (CT) imaging, nuclear magnetic resonance (MRI), positron emission computerized tomography (PET) etc.Every kind of imaging mode is compared with alternate manner and may be had unique advantage on disease, health or the anatomical abnormalities of screening and estimate some type, and this anatomical abnormalities for example comprises the calcification of polyp of colon, aneurysm, lung tuberosity, heart or arterial tissue, cancer Microcalcification or mass and various other damage or unusual of breast tissue.
For example, for the purpose of giving organ and other anatomical tissue imaging, can obtain the cross sectional image or the two dimension (2D) " section " of one group of patient's area-of-interest (ROI) with the CT imaging system.The purpose that this CT mode is generally used for diagnosing the illness, because this mode provides the exact image of size, shape and the position of the various anatomical structures of diagram such as organ, soft tissue and bone, and make to damage and more accurate such as the evaluation of the abnormal anatomy structure of cancer, polyp etc.
Internist, clinician, radiologist etc. are used for diagnosing and a kind of method of estimating health is manually to check the hard copy of the medical image of rebuilding from the data set that is obtained (x-ray film, print picture, photo etc.), to distinguish interested property feature.For example, the CT view data that obtains during CT examination can be used to produce one group of 2D medical image (x-ray film), and trained internist, clinician, radiologist etc. can organize the 2D medical image to this and observe to identify potential abnormal anatomy structure or damage.Yet the three-dimensional of 2D data (3D) is drawn and is typically for example made trained radiologist can determine whether suspicious structure is unusual really.
Various image processing systems and instrument have been developed and have helped internist, clinician, radiologist etc. to estimate medical image with diagnose medical conditions.For example, developed and be used for various clinical practices to be provided at computer aided detection and/or diagnosis (CAD) instrument that on the medical image health is detected automatically.Generally speaking, CAD system (is for example used view data, the CT data) digital signal processing method and/or technology are with automatic detection polyp of colon and other abnormal anatomy structure, such as the Microcalcification of the calcification of lung tuberosity, damage, aneurysm, heart or arterial tissue, breast tissue or mass etc.In addition, developed the checking tool that allows the user to select and mark the parts of images data.This CAD and checking tool are used to produce the position in the view data, and this position can be checked with 2D and 3D drawing technique.
The technology that a kind of and conventional cad tools is used in combination is the virtual coloscope inspection.When implementing the virtual coloscope inspection, function of use model (functional model) is surveyed from the Virtual Space of three-dimensional (3D) image rendering that is obtained by scanner.One of this model is a virtual camera, and it can be used as observer and/or operator, for example be positioned at the radiologist's of work station reference point, to survey this Virtual Space.Usually, the operator has two types photographing unit control, can pass through the Virtual Space according to photographing unit control operation person.
First kind is that the operator controls fully to photographing unit, its allow the operator at different positions and directional control photographing unit to realize required observation.In other words, the operator can guide photographing unit.This makes the operator can survey interested specific part and ignores other parts.Yet, in big virtual scope photographing unit fully control be irksome and tired, and the operator may its detection during do not observe all key characters, such as polyp of colon.
Second kind of technology of photographing unit control is pre-planned navigation, and it specifies the projected route that will carry out to photographing unit, and it does not need operator's interference.In other words, the operator is engaged in " self-navigation ".This makes the operator be primarily focused on the just observed Virtual Space, and needn't worry to bump against on the wall of checked environment.Yet this second kind of technology fully investigated for the enough time of operator and be followed the area-of-interest that the route line is observed.
Therefore, need a kind ofly will to use the data of CAD method output or from the bonded technology of the data of manual examination (check), thus the medical expert can be in a small amount of time by the Virtual Space and check position detected or institute's labelling.
Brief summary of the invention
The present invention is used for determining that by providing a kind of the position of observation bulge and the system and method for direction overcome foregoing problems and the other problem that known teachings runs into.
In an embodiment of the invention, be used for determining that the position of observation bulge and the method for direction comprise: at many rays of outward direction projection, wherein this is within bulge from a bit; Select at least one ray in these many rays, to be identified for observing the position and the direction of bulge; And position and the direction of using this at least one ray from many rays, select to be identified for observing bulge.These many rays are projected to a kind of in spherical and the elliposoidal shape.This bulge be tuberosity, damage, polyp, pre-cancer growth-gen and the growth of cancers thing in a kind of.
This method further comprises: obtain to comprise the medical image of this bulge, wherein this medical image is by a kind of acquisition the in computer tomography (CT), spiral CT, x-ray, positron emission computerized tomography, fluoroscopy, ultrasound wave and magnetic resonance (MR) imaging technique.This method also comprises: the auxiliary bulge detection technique that uses a computer detects bulge; Store position and direction determined, that be used to observe bulge; And observe this bulge from position and direction determined, that be used to observe bulge.This point is manually selected by the user.This point is the central point of this bulge.
Select a ray from this to this bulge surface experience beeline is identified for observing bulge in many rays position and direction.Stop at many rays of the voting surface (voting surface) of this bulge locating and be used to determine a ray from this to this bulge surface experience beeline in these many rays.The halt of these many rays determines by the gradient of image, and wherein this halt is used to determine in these many rays the ray of surface experience beeline from this to bulge.The halt of these many rays also uses the air threshold value to determine, wherein this halt is used to determine in these many rays the ray of surface experience beeline from this to bulge.
Select in these many rays from this to this bulge surface experience one group of ray of short average distance, to be identified for observing the position and the direction of this bulge.The direction that the rightabout of selected at least one ray is identified for observing bulge in many rays.The position that is used for the detected bulge of observation post is by selecting a bit to determine along the bearing of trend of selected at least one ray of these many rays.Selected point is to be a point of fixed range apart from this bulge surface, and the longest selected ray is extended this fixed range in air.This fixed range is based on the estimated size of this bulge.
When the surface point determined by one of selected ray and one group of ray on the bulge, more than second ray is projected onto the air section of cavity from this surface point.This more than second ray is projected to a kind of in spherical and the elliposoidal shape.Select long shot line in more than second ray to be identified for observing the position and the direction of bulge, the direction that wherein is used to observe bulge is opposite with the direction of selected long shot line.Use along one of any of this selected ray and estimated size of bulge and determine the position.
In yet another embodiment of the present invention, be used for comprising: be used for stored program memory device in the system of medical image development bulge; With the processor that this memory device communicates, this processor and program operate together with: at many rays of outward direction projection, wherein this is within bulge from a bit; From these many rays, select at least one ray to be identified for observing the position of bulge; And use selected at least one ray in these many rays to be identified for observing the position of bulge.
Select in these many rays a ray of surface experience beeline to be identified for observing the position of bulge from this to bulge.Selection from this to bulge surface experience one group of ray of short average distance be identified for observing the position of bulge.This is used for observing the position of bulge by selecting a bit to determine along the bearing of trend of selected at least one ray of these many rays.Selected point is to be a point of fixed range apart from this bulge surface, and the longest ray is extended this fixed range in air, and wherein this fixed range is based on the estimated size of this bulge.
The direction of selecting at least one ray in many rays to be identified for observing bulge.Select in these many rays a direction that ray is identified for observing bulge of surface experience beeline from this to bulge.The direction that the rightabout of selected at least one ray is identified for observing bulge in these many rays.Selection is surface experience one group of direction that ray is identified for observing bulge of short average distance from this to bulge.
When the surface point on the bulge is determined by one of selected ray and one group of ray, more than second ray is projected onto the air section of cavity from this surface point, wherein select ray the longest in this more than second ray to be identified for observing the position and the direction of bulge, the direction that wherein is used to observe bulge is opposite with the direction of selected long shot line.Use is determined the position along one of any of selected ray and estimated size of this bulge.
In another embodiment of the present invention, computer program comprises computer usable medium, this computer usable medium has record computer program logic thereon with the bulge that develops in medical image, this computer program logic comprises: be used for being projected to a kind of program code of spherical and ellipsoidal pattern from many rays of naming a person for a particular job, wherein this is within bulge; Be used for selecting the program code of at least one rays with the direction that is identified for observing bulge from these many rays; And be used for using many selected at least one rays of ray to be identified for observing the program code of the direction of bulge.
Select in these many rays a direction that ray is identified for observing bulge of surface experience beeline from this to bulge.Selection is surface experience one group of direction that ray is identified for observing bulge of short average distance from this to bulge.
The direction that the opposite direction of selected at least one ray is identified for observing bulge in these many rays.Select at least one ray in these many rays to be identified for observing the position of bulge.Select in these many rays a ray of surface experience beeline to be identified for observing the position of bulge from this to bulge.
Selection from this to bulge surface experience one group of ray of short average distance be identified for observing the position of bulge.Be used for observing the position of bulge by selecting a bit to determine along the bearing of trend of selected at least one ray of these many rays.Selected point is to be a point of fixed range apart from this bulge surface, and the longest ray is extended this fixed range in air, and wherein this fixed range is based on the estimated size of this bulge.
When the surface point on the bulge is determined by one of selected ray and one group of ray, more than second ray is projected onto the air section of cavity from this surface point, wherein select ray the longest in this more than second ray to be identified for observing the position and the direction of bulge, the direction that wherein is used to observe bulge is opposite with the direction of selected long shot line.Use is determined the position along one of any of selected ray and estimated size of this bulge.
In yet another embodiment of the present invention, be used for determining that the position of observation bulge and the system of direction comprise: be used for from some device at many rays of outward direction projection, wherein this is within bulge; Be used for selecting at least one ray to be identified for observing the position of bulge and the device of direction from these many rays; And be used for using many selected at least one rays of ray to be identified for observing the position of bulge and the device of direction.
In another embodiment of the present invention, be used for determining observing the position of polyp and the method for direction comprises at the image of colon: obtain the image of colon, wherein this image is by a kind of acquisition the in computer tomography (CT), spiral CT, x-ray, positron emission computerized tomography, fluoroscopy, ultrasound wave and magnetic resonance (MR) imaging technique; The auxiliary polyp detection technology that uses a computer detects polyp; A bit throw many rays in the polyp, wherein these many rays are projected to a kind of in spherical and the ellipsoidal pattern; The ray of selection experience beeline in surface from this to polyp is wherein selected a ray of surface experience beeline is identified for observing this polyp from this to polyp in these many rays position and direction; Use selected ray to be identified for observing the position and the direction of this polyp, wherein the opposite direction of selected ray is identified for observing the direction of this polyp, and be used to observe the position of this polyp by select to determine that a bit wherein selected point is to be a point of fixed range apart from this polyp surface along the bearing of trend of selected ray; And when carrying out the virtual navigation of colon, observe this polyp according to position and direction determined, that be used to observe this polyp.
Aforementioned feature is representative embodiments and is suggested to help to understand the present invention.Should be appreciated that these features not intention be considered to restriction of the present invention to being defined by the claims, perhaps to the equivalents of claim.Therefore, the summary of these features should not be considered to the determiner in definite equivalent.Supplementary features of the present invention will be in following explanation, become apparent from accompanying drawing and accessory rights require.
The accompanying drawing summary
Fig. 1 is the block diagram of the system of position according to an illustrative embodiment of the invention, that be used for definite observation bulge and direction;
Fig. 2 is the flow chart that the method for position according to an illustrative embodiment of the invention, that be used for definite observation bulge and direction is shown;
Fig. 3 illustrates position and the direction that is identified for observing bulge according to an illustrative embodiment of the invention;
Fig. 4 A be according to an illustrative embodiment of the invention, be identified for observing the position of bulge and another diagrammatic sketch of direction;
Fig. 4 B be according to an illustrative embodiment of the invention, be identified for observing the position of bulge and the another diagrammatic sketch of direction;
The polyp of the institute's labelling in the colon is shown Fig. 5 " unsettled-around (flying-around) "; And
Colon according to an illustrative embodiment of the invention is shown Fig. 6 " unsettled-by (flying-through) ".
The detailed description of illustrative embodiments
Fig. 1 is the block diagram of the system 100 of position according to an illustrative embodiment of the invention, that be used for definite observation bulge and direction.As shown in fig. 1, system 100 especially comprises scanning device 105, personal computer (PC) 110 and operator's control station and/or the virtual navigation terminal 115 that for example connects by ethernet network 120.Scanning device 105 can be nuclear magnetic resonance (MRI) equipment, computerized tomography (CT) imaging device, spiral CT equipment, positron emission computerized tomography (PET) equipment, two dimension (2D) or three-dimensional (3D) fluoroscopy imaging device, 2D, 3D or the four-dimension (4D) supersonic imaging device or x-ray equipment etc.
Can be portable or the PC110 of laptop computer, PDA(Personal Digital Assistant) etc. comprise with input 150 with export 155 CPU that is connected (CPU) 125 and memorizeies 130.This CPU125 comprises visualization module 145, and this visualization module 145 comprises that one or more is used for determining to observe the position of bulge and the method for direction at medical image.CPU125 can also comprise detection module and diagnostic module, this detection module is computer aided detection (CAD) module, be used for the bulge at medical image detection such as polyp, this diagnostic module is used to carry out the automatic diagnosis or the Function of Evaluation of medical image.
Memorizer 130 comprises random-access memory (ram) 135 and read only memory (ROM) 140.Memorizer 130 can also comprise data base, disc driver, tape drive etc. or its combination.RAM135 plays data storage, and it is stored among the CPU125 during the performing a programme employed data and is used as the working area.ROM140 plays the program memorizer, is used for being stored in the performed program of CPU125.Input 150 is made up of keyboard, mouse etc., is made up of liquid crystal display (LCD), cathode ray tube (CRT) display, printer etc. and export 155.
The operation of system 100 is controlled by virtual navigation terminal 115, and this virtual navigation terminal 115 comprises controller 165, for example keyboard and display 160, for example CRT monitor.Virtual navigation terminal 115 communicates with PC110 and scanning device 105, also can observe on display 160 thereby can be depicted as the 3D data by PC110 by the 2D view data that scanning device 105 is collected.Should be appreciated that, PC110 can be configured under the situation that does not have virtual navigation terminal 115 for example to use input 150 and the operation of output 155 equipment and the information that is provided by scanning device 105 is provided, uses this input 150 and 155 equipment of output to move by some performed task of controller 165 and display 160.
As shown in fig. 1, visualization module 145 also is used for receiving and handling digital medical image data by PC110, as described above such, this digital medical image data can be the form such as raw image data, 2D data reconstruction (for example, axial slices) or the 3D data reconstruction of any combination of volumetric image data or many planes reformatting or such form.Data processed result can be output to image drawing system the virtual navigation terminal 115 from PC110 via network 120, be used for producing the 2D of view data and/or 3D draws the cutting apart of this data processed result such as organ or anatomical structure, color or brightness flop or the like according to data processed result.
Should be appreciated that, according to of the present invention, be used for determining medical image observe the CAD system of the position of bulge and direction and method can be implemented as to the expansion of traditional CAD methods or alternative, such as manual selection or be used for image data processing other develop automatically and detection method.In addition, should be appreciated that, example system described herein and method can easily utilize 3D medical image and CAD system or application program to realize, 3D medical image and CAD system or application program be suitable for widely imaging mode (for example, CT, MRI etc.) and be suitable for diagnosis and estimate various abnormal anatomy structures or damage, such as polyp of colon, aneurysm, lung tuberosity etc.In this, although describe illustrative embodiments with reference to specific imaging mode or particular anatomical features here, should not be considered to limit the scope of the invention.
Be also to be understood that the present invention can hardware, the various forms of software, firmware, application specific processor or its combination realizes.In one embodiment, the present invention realizes with software, as being implemented in the application program on the program storage device (for example, floppy disc, RAM, CD ROM, DVD, ROM and flash memory) effectively.This application program can be loaded on the machine that comprises any appropriate configuration and by this machine and move.
Fig. 2 illustrates the flow chart of operation according to an illustrative embodiment of the invention, that be used for determining observing at medical image the method for the position of bulge and direction.As shown in Figure 2, the 3D data obtain from the medical image of bulge, and this bulge is colon (step 205) in this example.Thereby this produces a series of 2D images relevant with this colon and realizes by using scanning device 105, for example CT scanner scanning colon in the operation of virtual navigation terminal 115 places.These 2D images of colon can be transformed or convert to the image that 3D draws then.Should be appreciated that this medical image can be a cavity, can also be any in pancreas, bronchus, larynx, trachea, hole, auditory meatus, blood vessel, urethra and the bladder etc. except that colon.This medical image can also be non-tubular structure, such as lung soft tissue or liver.
After colon acquisition 3D data, the 3D data of this colon are handled, to detect polyp (step 210).More precisely, use tradition (CAD) technology to detect polyp.Should be appreciated that, can use various traditional C AD technology according to the present invention.In addition, during step 210, the medical expert can manually select polyp from medical image, for example by using mouse or computer input unit, selecting the part medical image such as input 150.
As further illustrating among Fig. 2, after receiving the data relevant with polyp, the point (for example central point) of ray from each polyp throws (step 215).After asking this data, the operator these points can be offered the operator of virtual navigation terminal 115.This operator can also manually select this point by labelling in polyp, draw with the 3D endoscope of observing polyp in the center of the 2D image of polyp for example, as top discussing in the step 210.These rays use the ray projective technique to be projected to spherical pattern and/or shape then.For example when data were anisotropy, these rays can be projected to ellipsoidal pattern.The example of many rays of the central point projection from polyp is shown in Figure 3, and will more go through below.
Be defined as a little and direction from every ray of the central point of one or more polyps projection.These rays pass solid matter, such as tissue, but in air, stop.As shown in Figure 3, these rays begin and run into air in assigned direction continuity up to these rays from central spot.Exemplary ray can be defined as P+t*V on mathematics, wherein P=(a, b are some c), and V=(x, y z) are the vector of definition direction.Attempt different directions to cover all possible direction by the system increase elevation angle and azimuthal angle.Length is defined as the maximum of t, so that vector remains in the polyp and do not contact with air.
After the projection of the ray point from each polyp, select the ray (step 220) of surface experience beeline from this to polyp.Every ray is for example from this some projection and/or extend, crossing up to its surface with colon.Distance from this to colon surface is a stop distance.Therefore, the ray with shortest length is to have the ray of short stop distance.Replacedly, can select to have one group of ray of short average length in step 220, for example, average by the stop distance to many groups N bar ray, wherein N is predetermined number.After averaging, select that to have the group of the shortest meansigma methods or average stop distance.
Determining that point from polyp can make in all sorts of ways to the distance on polyp surface defines.In one approach, can use gradient difference to determine which bar ray halt also is used to determine will select thus or where organizes ray in step 220.This finishes by the standard method of using the computed image gradient.Trend towards having the sharp keen edge of high gradient, such as easier being identified in border between air and colon wall and/or the tissue.Therefore, surpass predetermined threshold set, for example become the stop distance of ray in the tonsure at high gradient magnitude place more.
In another approach, can use the air threshold value to determine the stop distance of ray.For example, can calibrate scanning device 105, thereby air will have a certain numerical value or numerical range in the image that is obtained, and soft tissue, will have different numerical value or numerical range such as blood.After calibration scan equipment 105, threshold value can be set, this threshold value drops on the mid point between the value of the value of air and soft tissue, and this mid point is best for cutting apart colon, and can determine the stop distance of ray thus.In another alternative, when using cad technique, have only the ray that intersect on those and " the voting surface " of detected polyp will be used to definite stop distance, and select its shortest ray thus." voting surface " is defined as the voxel of colon surface and the intersection point of those voxels that cause polyp detection, and those voxels that cause polyp detection are along with employed cad technique changes.This technology is disclosed at the U.S. Patent application (attorney docket is 2003P08958US) of " Methodand System for Response Image Feature Collection and CandidateSummit; Surface and Core Estimation (method and system that is used for response image feature collection and candidate vertices, surface and core assessment) " by name, and the copy of this U.S. Patent application is hereby incorporated by.
Shown in Fig. 2 is further,, use selected ray or ray groups to be identified for the position and the direction (step 225) of the detected polyp of observation post in case selected this ray or this group ray.In other words, determined for observing the distance that polyp places virtual camera away from polyp and the direction of camera rotational angle.Should be appreciated that, be generally equal to central point from polyp to the beeline on polyp surface, be held in place in the air part in the inner space of colon thereby this distance is restricted this distance away from the distance of polyp.This distance also can be configured to fixed value by colon detected at all and/or institute's labelling.
The shortest ray and/or ray groups have defined from the outside direction of the central point of colon.As a result, the point of selecting along this shortest ray has been determined the observation place in the air part of colon, and this opposite direction of short ray determined direction of observation.More precisely, this drawing direction of short ray be its contrary direction, thereby this photographing unit so placed so that this photographing unit sees polyp backward, as shown in Figure 3.For example, (as shown in Fig. 4 A) determined by extend the shortest ray in the air space of colon in the observation place, and determines to remain on the position in the air space and make whole polyp in the visual field of for example photographing unit shown in Fig. 4 A along this ray.This shortest ray can extend from the surface of polyp up to following the two one of: (1) this ray is run into the relative wall of colon, and perhaps (2) whole polyp depends on which incident takes place earlier in the visual field.Should be appreciated that, determine whether whole polyp in the visual field, depend on be the selected visual field of photographing unit, this visual field simulated and be the hypothesis the polyp diameter.This diameter can be configured to default value, such as one centimetre, perhaps estimate by traditional approach.
Fig. 4 B illustrates and is used for determining the position of the detected polyp of observation post and the another kind of method of direction.As shown in Fig. 4 B, the spherical set of ray (spherical set) is from the surface point projection of (in the polyp surface) intersection point of the shortest ray.These rays are run into solid state surface through air up to these rays.The long shot line of ray groups is used to then to determine that the position of virtual camera and direction observe being used for.This position is selected as the point along this ray, and this position can be the fixed range in the air section, and perhaps it also can change according to estimated polyp size.
After step 225, determined, as to be used for the detected polyp of observation post position and direction are used to increase existing program then or are used to produce new " unsettled-as to pass through " program, to pass through colon or any other cavity (step 230).Before producing " unsettled-by " program, can for example be stored in the memorizer 130 of CPU125 with the data of determined, as to be used for the detected polyp of observation post position and directional correlation, be used for further operation and/or analyze.In addition, when being given in the data of step 225 acquisition, can produce some extra actions: the operator of (1) virtual navigation terminal 115 can use it to be labeled and/or detected each polyp to observe immediately, perhaps (2) its can be used to provide photography around polyp, so that the medical expert from a plurality of sides and/or angle observe polyp, as shown in Figure 5.
In case programmed " unsettled-by ", the medical expert just can be along " unsettled-as to pass through " path by colon (step 235).In other words, the operator of virtual navigation terminal 115 carries out the navigation of being planned or guided according to " unsettled-by " just checked virtual organ, as shown in Figure 6.As shown in Figure 6, should " unsettled-by " advance to the primary importance (A) (just, the first determined position that is used to observe) in the virtual organ immediately, directly take the operator to detected polyp to observe thus.In this, should " unsettled-by " will suspend and allow the detected polyp of operator observation post (just, using determined direction of observation observation polyp), and advance to the second position (B) then observing, or the like.In addition, " unsettled-by " plane of intersecting with virtual camera can be provided, thus this virtual camera can still, still allow the operator to operate this photographing unit when needs not having to pass through virtual environment under the interactive situation of operator automatically.
According to the present invention, the position that is used to observe bulge can automatically be determined with direction and be used to produce and/or program that increase is relevant with the virtual navigation of cavity.For example, utilize " unsettled-by " of the programming of position and directional information to make the operator of virtual navigation terminal can directly advance to the bulge that use traditional C AD technology for detection arrives according to the present invention, and do not need the manual navigation virtual camera to pass through cavity.Therefore, the application of the invention, traditional CAD system can be enhanced with generation and/or the increase program relevant with the virtual navigation of cavity, thus improve the speed that the user analyzes by detected bulge and check before detected bulge.
Should be appreciated that, because some the system's building blocks and the method step that are described in the drawings can realize by software, the mode that the actual connection between the system unit (perhaps process steps) can be programmed according to the present invention and difference.The present invention provides instruction here, and those of ordinary skills can expect these and similar implementation or configuration of the present invention.
Should be appreciated that foregoing description is only represented illustrative embodiments.For convenience of the reader, foregoing description concentrates on the representative example of possible embodiment, and example is the explanation of inventive principle.This description is not attempted exhaustive all possible variation.Interchangeable embodiment may not present at specific part of the present invention, perhaps can use other alternative of not describing for a part yet, can not think that these optional embodiments do not have claimed.Under the situation that does not deviate from the spirit and scope of the present invention, can directly realize other application and embodiment.Therefore, the present invention is intended to not to be subjected to the special embodiment of describing to limit, because can produce many arrangements and combination and foregoing is comprised the replacement of non-creativeness foregoing, but the present invention limits according to claims.Should be appreciated that many embodiments that those do not have to describe are in the literal scope of claims, and other is of equal value.
Claims (47)
1, a kind of being used for determined to observe the position of bulge and the method for direction, and it comprises:
At many rays of outward direction projection, wherein this is within bulge from a bit;
From these many rays, select at least one ray to be identified for observing the position and the direction of this bulge; And
Use selected at least one ray is identified for observing this bulge in these many rays position and direction.
2, the method for claim 1, wherein described many rays are projected to a kind of in sphere and the elliposoidal shape.
3, the method for claim 1, wherein described bulge be tuberosity, damage, polyp, pre-cancer growth-gen and the growth of cancers thing in a kind of.
4, the method for claim 1 further comprises:
Acquisition comprises the medical image of described bulge.
5, method as claimed in claim 4, wherein, described medical image is by a kind of acquisition the in computer tomography (CT), spiral CT, x-ray, positron emission computerized tomography, fluoroscopy, ultrasound wave and magnetic resonance (MR) imaging technique.
6, the method for claim 1 further comprises:
The auxiliary bulge detection technique that uses a computer detects described bulge.
7, the method for claim 1, wherein describedly manually select by the user.
8, the method for claim 1, wherein described some central point that is described bulge.
9, position and the direction of the method for claim 1, wherein selecting a ray of the experience beeline of the surface from described to described bulge in described many rays to be identified for observing this bulge.
10, method as claimed in claim 9, wherein, many rays that stop at the voting surface of described bulge are used to determine a ray of the experience of the surface from described to this bulge beeline in these many rays.
11, method as claimed in claim 9, wherein, the halt of described many rays is determined that by the gradient of image wherein this halt is used to determine a ray of the experience of the surface from described to this bulge beeline in these many rays.
12, method as claimed in claim 9 wherein, uses the air threshold value to determine the halt of described many rays, and wherein this halt is used to determine a ray of the experience of the surface from described to this bulge beeline in these many rays.
13, the method for claim 1, wherein select one group of ray of short average distance of the experience of the surface from described to described bulge in described many rays, to be identified for observing the position and the direction of described bulge.
14, the direction that the opposite direction of selected at least one ray is identified for observing described bulge in the method for claim 1, wherein described many rays.
15, the method for claim 1 further comprises:
Store position and direction determined, that be used to observe described bulge.
16, the method for claim 1 further comprises:
Observe described bulge from position and direction determined, that be used to observe described bulge.
17, the method for claim 1, wherein be used for the position of the detected bulge of observation post by selecting a bit to determine along the bearing of trend of selected at least one ray of described many rays.
18, method as claimed in claim 17, wherein, selected point is that the surface apart from this bulge is a point of fixed range, and selected long shot line is extended this fixed range in air.
19, method as claimed in claim 18, wherein said fixed range is based on the estimated size of described bulge.
20, the method for claim 1, wherein when the surface point determined by one of selected ray and one group of ray on the described bulge, more than second ray is projected onto the air section of cavity from this surface point.
21, method as claimed in claim 20, wherein said second group of many ray are projected to a kind of in spherical and the elliposoidal shape.
22, method as claimed in claim 20 is wherein selected the longest ray in described more than second ray, and to be identified for observing the position and the direction of described bulge, the direction that wherein is used to observe this bulge is opposite with the direction of selected long shot line.
23, method as claimed in claim 22, wherein said position are used along one of estimated size of any of selected ray and this bulge and are determined.
24, a kind of system that is used at medical image development bulge, it comprises:
Be used for stored program memory device;
With the processor that this memory device communicates, this processor and this procedure operation with:
At many rays of outward direction projection, wherein this is within bulge from a bit;
From these many rays, select at least one ray to be identified for observing the position of this bulge; And
Use selected at least one ray in these many rays to be identified for observing the position of this bulge.
25, system as claimed in claim 24 wherein, selects a ray of the experience beeline of the surface from described to described bulge in described many rays to be identified for observing the position of this bulge.
26, system as claimed in claim 24 wherein, selects surface from described to described bulge to experience one group of ray of short average distance, to be identified for observing the position of this bulge.
27, system as claimed in claim 24 wherein, is used for observing the position of described bulge by selecting a bit to determine along the bearing of trend of selected at least one ray of described many rays.
28, method as claimed in claim 27, wherein, selected point is that the surface apart from described bulge is a point of fixed range, and the longest ray is extended this fixed range in air, and wherein this fixed range is based on the estimated size of described bulge.
29, at least one ray wherein, is selected, to be identified for observing the direction of described bulge by system as claimed in claim 24 from described many rays.
30, a direction that ray is identified for observing described bulge of the experience of the surface from described to described bulge beeline in described many rays wherein, is selected by system as claimed in claim 29.
31, system as claimed in claim 29, wherein, the direction that the opposite direction of selected at least one ray is identified for observing described bulge in described many rays.
32, system as claimed in claim 29 wherein, selects surface from described to described bulge to experience one group of ray of short average distance, to be identified for observing the direction of described bulge.
33, system as claimed in claim 29, wherein, when the surface point determined by one of selected ray and one group of ray on the described bulge, more than second ray is projected onto the air section of cavity from described surface point, wherein select ray the longest in this more than second ray to be identified for observing the position and the direction of described bulge, the direction that wherein is used to observe described bulge is opposite with the direction of selected long shot line.
34, method as claimed in claim 33, wherein, described position is used along one of estimated size of any of selected ray and described bulge and is determined.
35, a kind of computer program that comprises computer usable medium, this computer usable medium have record computer program logic thereon with the bulge that develops in medical image, this computer program logic comprises:
Be used for being projected to a kind of program code of spherical and ellipsoidal pattern from many rays of naming a person for a particular job, wherein this is within bulge;
Be used for selecting the program code of at least one rays with the direction that is identified for observing this bulge from these many rays; And
Be used for using selected at least one ray of these many rays to be identified for observing the program code of the direction of this bulge.
36, a direction that ray is identified for observing described bulge of the experience of the surface from described to described bulge beeline in described many rays wherein, is selected by system as claimed in claim 35.
37, system as claimed in claim 35 wherein, selects surface from described to described bulge to experience one group of direction that ray is identified for observing described bulge of short average distance.
38, system as claimed in claim 35, wherein, the direction that the opposite direction of selected at least one ray is identified for observing described bulge in described many rays.
39, system as claimed in claim 35 wherein, selects at least one ray in described many rays to be identified for observing the position of described bulge.
40, system as claimed in claim 39 wherein, selects a ray of the experience beeline of the surface from described to described bulge in described many rays to be identified for observing the position of described bulge.
41, system as claimed in claim 39 wherein, selects surface from described to described bulge to experience the position that one group of ray of short average distance is identified for observing described bulge.
42, system as claimed in claim 39 wherein, is used for observing the position of described bulge by selecting a bit to determine along the bearing of trend of selected at least one ray of these many rays.
43, system as claimed in claim 42, wherein selected point is that the surface of the described bulge of distance is a point of fixed range, and the longest ray is extended this fixed range in air, and wherein this fixed range is based on the estimated size of described bulge.
44, system as claimed in claim 39, wherein, when the surface point on the described bulge is determined by one of selected ray and one group of ray, more than second ray is projected onto the air section of cavity from described surface point, wherein, select the longest ray in this more than second ray, to be identified for observing the position and the direction of described bulge, the direction that wherein is used to observe described bulge is opposite with the direction of selected long shot line.
45, system as claimed in claim 44, wherein said position is used along one of estimated size of any of selected ray and described bulge and is determined.
46, a kind of being used for determined to observe the position of bulge and the system of direction, and it comprises:
Be used for from some device at many rays of outward direction projection, wherein this is within this bulge;
Be used for selecting at least one ray to be identified for observing the position of this bulge and the device of direction from these many rays; And
Be used for using selected at least one ray of these many rays to be identified for observing the position of this bulge and the device of direction.
47, a kind ofly be used for determining observing the position of polyp and the method for direction at the image of colon, it comprises:
Obtain the image of colon, wherein this image is by a kind of acquisition the in computer tomography (CT), spiral CT, x-ray, positron emission computerized tomography, fluoroscopy, ultrasound wave and magnetic resonance (MR) imaging technique;
The auxiliary polyp detection technology that uses a computer detects this polyp;
A bit throw many rays in the polyp, wherein these many rays are projected in spherical and the ellipsoidal pattern one;
The ray of the surface experience beeline of selection from this to polyp, position and the direction of wherein selecting a ray of the experience of the surface from this to polyp beeline in these many rays to be identified for observing this polyp;
Use selected ray to be identified for observing the position and the direction of this polyp, wherein, the opposite direction of selected ray is identified for observing the direction of this polyp, and the position that is used to observe this polyp is a bit determined by selecting along the bearing of trend of selected ray, and wherein selected point is that the surface apart from this polyp is a point of fixed range; And
When carrying out the virtual navigation of colon, observe this polyp from position and direction determined, that be used to observe this polyp.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US48259103P | 2003-06-25 | 2003-06-25 | |
| US60/482,591 | 2003-06-25 | ||
| US10/873,337 | 2004-06-22 |
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| Publication Number | Publication Date |
|---|---|
| CN1842297A true CN1842297A (en) | 2006-10-04 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 200480024408 Pending CN1842297A (en) | 2003-06-25 | 2004-06-24 | System and method for polyp visualization |
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| CN (1) | CN1842297A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN116211260A (en) * | 2023-05-09 | 2023-06-06 | 西南医科大学附属医院 | Kidney stone form three-dimensional imaging system and method based on zooming scanning |
-
2004
- 2004-06-24 CN CN 200480024408 patent/CN1842297A/en active Pending
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN116211260A (en) * | 2023-05-09 | 2023-06-06 | 西南医科大学附属医院 | Kidney stone form three-dimensional imaging system and method based on zooming scanning |
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