CN1762300A - Human body physiological parameter monitor device based on high frequency light capacity trace signal - Google Patents

Human body physiological parameter monitor device based on high frequency light capacity trace signal Download PDF

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CN1762300A
CN1762300A CN 200410084057 CN200410084057A CN1762300A CN 1762300 A CN1762300 A CN 1762300A CN 200410084057 CN200410084057 CN 200410084057 CN 200410084057 A CN200410084057 A CN 200410084057A CN 1762300 A CN1762300 A CN 1762300A
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trace signal
capacity trace
light capacity
signal
unit
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CN100502768C (en
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张元亭
郑定昌
滕晓菲
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Chinese University of Hong Kong CUHK
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Chinese University of Hong Kong CUHK
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Abstract

The invention discloses a method for measuring heart rate and blood pressure by employing the photo volume marking signal of the body terminal organization and the measuring device, comprising: combining the high-frequency photo volume marking signal with the electrocardiosignal to measure the body physiological parameter. The disclosed method and device can remove the industrial frequency interference of 50 Hertz and other instantaneous high-frequency interference, and reducing the signal distortion resulted by the low-frequency motion noise, which makes the measurement of the body physiological parameter more precise.

Description

Human body physiological parameter monitor device based on high frequency light capacity trace signal
Technical field
The present invention relates to method and device that human body physiological parameter is measured, relate in particular to method and the device physiological parameters such as heart rate and blood pressure measured based on high frequency light capacity trace signal (Photoplethysmography).
Technical background
Current blood pressure measuring method has intrusive mood to measure and non-intrusion measurement two big classes.The intrusive mood measurement is a kind of direct measuring method, will be inserted into a conduit in the tremulous pulse during measurement, measures arterial pressure by the transducer that is connected with fluid column.This method need be by professional health care personnel operation and expense height.Moreover, cause danger such as bacterial infection, severe loss of blood easily because this is an invasive operation.
Non-intrusion measurement is a kind of indirect measurement method.This method is safe in utilization, convenient, comfortable, is the method for measurement blood pressure commonly used in the present hospital.This method is also needed the patient of long term monitoring blood pressure to use at home by more and more.Because the public recognizes this healthy killer's of hypertension hazardness day by day, and the importance of diagnosing as early as possible and treating, use the consumer of non-invasion blood pressure meter constantly increasing.The non-invasion blood pressure meter mainly contains three kinds: pulse sphygomanometer, tone are measured sphygomanometer and based on the sphygomanometer in pulse wave transmission time.
The method of using the pulse sphygomanometer to measure blood pressure has two kinds, and a kind of is auscultation, and another kind is a succusion.
The auscultation ratio juris is to collect the Ke Shi sound.Whole sphygomanometer comprises cuff, mercury gauge (the employing electronic pressure transmitter is also arranged in recent years) and the stethoscope that can charge and discharge gas.When measuring the upper limb blood pressure, open the mercury column switch earlier, the air in the cuff is driven to the greatest extent.Then cuff is twined in upper arm, find out beating of brachial artery, put stethoscopic chest piece and locate, have the air bag of valve alive to inflate to cuff with the finger pressure zone in this.Mercury column or indicator move immediately, when mercury column rises to default value, promptly stop inflation.Then, open balloon valve alive and slowly exit, mercury column is slowly decline (indicator revolution) then.Observe the scale that mercury column or indicator move this moment.If hear first sound equipment of brachial artery, shown in scale be systolic blood pressure, be called for short systolic pressure; Sound equipment dies down suddenly or when can't hear, scale is designated as diastolic blood pressure when mercury column drops to, and is called for short diastolic pressure.But this method can only be determined systolic pressure and diastolic pressure, and is not suitable for some the 5th Ke Shi sound than the extremely unheard patient of overly soft pulse.
Succusion can remedy the above-mentioned deficiency of auscultation, and the patient more weak for the Ke Shi sound also can measure blood pressure.During use cuff is twined in upper arm, cuff is charged and discharged gas.Determine pressure value by measurement oscillation amplitude of pressure in expansible cuff then.The vibration of pressure is by arterial vascular contraction and expands caused.The numerical value of systolic pressure, mean pressure and diastolic pressure can be monitored the pressure this cuff and be obtained when this cuff is slowly exitted.Mean pressure is engraved in the pressure in the attenuating device of this cuff during corresponding to envelope peak.Systolic pressure was estimated as before this envelope peak moment that amplitude corresponding to this envelope equals a ratio of this peak amplitude usually and locates pressure in the attenuating device of this cuff.Diastolic pressure is estimated as after the peak value of this envelope moment that amplitude corresponding to this envelope equals a ratio of this peak amplitude usually and locates pressure in the attenuating device of this cuff.Use different ratio values can have influence on the accuracy of blood pressure measurement.
Most of product in the market all is to adopt auscultation or succusion.But, therefore be difficult to frequently measure and continuous measurement because these two kinds of methods all need cuff is charged and discharged gas.And, the frequency of its measurement also be subjected to cuff inflate the needed time and when measuring to the restriction of this needed time of cuff deflation.Usually, once complete blood pressure measurement needs about 1 minute.In addition, the size of cuff also can impact the measurement result of blood pressure.
The ultimate principle that tone is measured sphygomanometer is: when blood vessel was subjected to the external object compressing, the circumferential stress of blood vessel wall had been eliminated, and at this moment intrinsic pressure the and external pressure of blood vessel wall equates.By to the tremulous pulse pressurization, tremulous pulse is flattened.Record makes tremulous pulse keep flat pressure.Utilize one group to place surperficial eparterial pressure transducer group to measure this pressure, and therefrom calculate patient's blood pressure.But the shortcoming of this method is that the cost of the pick off of its use is higher, and its certainty of measurement is subjected to the influence of measuring position easily, so unpopular on market.
Sphygomanometer based on the pulse wave transmission time is determined blood pressure according to the relation between arteriotony and the pulse wave transmission speed.When increased blood pressure, vasodilation, the pulse wave transmission speed is accelerated, on the contrary the pulse wave transmission speed slows down.This sphygomanometer can utilize photoelectric sensor to gather light capacity trace signal in use, and further draws heart rate, blood pressure by this.This method can provide simple portable blood pressure measuring device, and its development cost is lower, can realize the long-time continuous of arteriotony is measured.
Human body physiological parameter measuring device based on light capacity trace signal mainly comprises light source and photoelectric sensor.The operation principle of obtaining light capacity trace signal is when light impinges upon the tip tissue, for example: finger, ear-lobe, toe etc., part light can be absorbed or reflection by skin, bone, muscular tissue, blood etc., remaining light can pass the tip tissue, and photoelectric sensor is responded to these reflected light or transillumination.Pulse is beaten, and the variation of blood flow causes the light intensity of reflected light and transillumination to change in the blood vessel that causes, and photoelectric sensor can be responded to its variation, and this change transitions is become the signal of telecommunication.The light that light source sends can be visible light (particularly HONGGUANG and green glow, it is 680 and 530 nanometers that wavelength is about respectively) or infrared light (wavelength is 880 or 940 nanometers).
Yet, the spectral range of the light capacity trace signal that is utilized based on the human body physiological parameter measuring device of light capacity trace signal is from 0.5 hertz to 35 hertz, and the signal in this spectral range is easy to be subjected to the low frequency movement noise jamming and causes distorted signals and then cause the inaccurate of measurement.More accurate for the measurement that makes human body physiological parameter, must reduce because the distorted signals that the low frequency movement noise is caused.The present invention proposes therefrom.
Summary of the invention
The present invention makes with regard to being based on the above-mentioned problems in the prior art.Its objective is provides the device and method that can accurately measure human body physiological parameter, especially to the monitoring of heart rate and blood pressure.
To achieve these goals, first aspect of the present invention provides a kind of device that obtains high frequency light capacity trace signal.The spectral range of the high frequency light capacity trace signal of this device recording from 10 hertz to 35 hertz about, comprise will obtain from human body light capacity trace signal amplify and Filtering Processing through signal.Preferably, light capacity trace signal obtains from the tip tissue of human body.Method of the present invention can be removed 50 hertz of power frequencies and disturb, and other instantaneous High-frequency Interference, and main is can reduce because the distorted signals that the low frequency movement noise is caused obtains stable light capacity trace signal.
Second aspect of the present invention provides a kind of device that utilizes high frequency light capacity trace signal to measure heart rate, comprises the light capacity trace signal collecting unit, is used to gather the high frequency light capacity trace signal of human body tip tissue; Microprocessor unit is handled the high frequency light capacity trace signal that is obtained; And display unit, show through microprocessor unit and handle resultant heart rate.
Heart rate measurement device of the present invention can realize low-power consumption, lightly change and the requirement of miniaturization, and be fit to embed multiple jewelry such as the wrist-watch, finger ring, earrings that is worn on one's body, or in belongings such as cell phone, palm PC, laptop computer, electronic pet, the key chain etc.
The 3rd aspect of the present invention provides a kind of device that utilizes high frequency light capacity trace signal to measure blood pressure, comprising:
The light capacity trace signal collecting unit is used to gather the high frequency light capacity trace signal of human body tip tissue;
The ecg signal acquiring unit, the electrocardiosignal that is used to gather human body;
The Signal Pretreatment unit, it is electrically connected with described ecg signal acquiring unit and described light capacity trace signal collecting unit, is used for electrocardiosignal and light capacity trace signal from described ecg signal acquiring unit and described light capacity trace signal collecting unit are carried out pretreatment;
Input block is used to import the human blood-pressure reference value;
Microprocessor unit is electrically connected with Signal Pretreatment unit, input block respectively, with described blood pressure reference value with handle through the signal of Signal Pretreatment cell processing, obtain pressure value.
Because the present invention has collected light capacity trace signal, if suitably add induction apparatus and the signal pre-processing circuit thereof of gathering electrocardiosignal, application just can realize the measurement of sleeveless belt continuous blood pressure based on the pulse wave transmission time theory of electrocardiosignal and light capacity trace signal.
The 4th aspect of the present invention provides a kind of method of blood pressure measurement, and this method may further comprise the steps:
A) provide the electrocardiosignal and the high frequency light capacity trace signal of human body;
B) selecting first reference point on the described electrocardiosignal and on described high frequency light capacity trace signal, selecting second reference point;
C) obtain the human pulse ripple transmission time according to described two reference points; And
D) described pulse wave transmission time and human blood-pressure reference value are handled, obtain pressure value.
In the present invention, employed light capacity trace signal collecting unit can further comprise the Signal Pretreatment unit, and the light capacity trace signal that is used for collecting is transformed into high frequency light capacity trace signal.
In an embodiment of light capacity trace signal collecting unit, it can comprise the pick off of the light capacity trace signal that is used to gather human body tip tissue.And selectable pick off is light emitting diode and light-sensitive element such as optical inductor.
Among the present invention, the Signal Pretreatment unit can comprise carry out the circuit of filtering and amplification from the light capacity trace signal of described light capacity trace signal collecting unit.
In device of the present invention, the wireless data transmission unit that also comprises the display unit that is used for display of blood pressure or heart rate and be used for blood pressure or heart rate measurements are transferred to remote terminal.
In an embodiment of blood pressure measuring method of the present invention, the pulse wave transmission time of described step c) can be determined by the interval that calculates between described two reference points.Preferably, the reference point on the described electrocardiosignal is the point on the R type ripple in the electrocardiosignal, more preferably, selects top point conduct on the R type ripple with reference to point.
In another embodiment, the reference point on the described high frequency light capacity trace signal can but be not limited to the top point of signal.In addition, further comprise the step that the pulse wave transmission time is averaged in the described step c).And the meansigma methods in described pulse wave transmission time is preferably the meansigma methods of the data of record in 10 seconds.
In an embodiment more of the present invention, described step d) can further may further comprise the steps:
D-1) utilize the reference pressure value of input block input and in the described pulse wave transmission time measured during with reference to blood pressure measurement, calculate the parameter value among the formula (being the blood pressure measurement formula) of pulse wave transmission time and blood pressure relation, be kept in the described microprocessor unit; And
D-2) the described blood pressure measurement formula of pulse wave transmission time substitution that is obtained in will measuring in real time embodies in the formula to calculate blood pressure.
In another embodiment of blood pressure measuring method of the present invention, described method also can comprise the step of utilizing wireless data transmission unit the pressure value that records to be sent to remote terminal.This step can comprise and at first blood pressure measurement is transferred to a wireless data transmission unit that is built in the blood pressure measuring device, and then sending it in the user short range wireless data receiving element, this unit can be transferred to data in the microprocessor of computer to do further processing by microprocessor.
Brief Description Of Drawings
Fig. 1 for same measured under not motion noise situations and have a light capacity trace signal that writes down under the motion noise situations;
Fig. 2 for same measured under not motion noise situations and have a high frequency light capacity trace signal that writes down under the motion noise situations;
Fig. 3 is a flow chart of measuring heart rate in the one embodiment of this invention;
Fig. 4 is the structural representation of blood pressure measuring device one embodiment according to the present invention;
Fig. 5 is the middle according to one embodiment of the present invention flow chart of measuring blood pressure;
Fig. 6 is a flow chart of realizing a specific embodiments of calibration process shown in Figure 5;
Fig. 7 is a flow chart of realizing a specific embodiments in definite pulse wave transmission time shown in Figure 5;
Fig. 8 is a flow chart of realizing a specific embodiments of definite blood pressure shown in Figure 5;
Fig. 9 is the specific embodiments that the present invention measures heart rate device, the sketch map of finger ring type cardiotachometer;
Figure 10 is the specific embodiments that the present invention measures blood pressure device, the sketch map of wrist formula wrist-watch sphygomanometer.
The present invention describes in detail
By following detailed explanatory note also with reference to the accompanying drawings, it is clearer that above-mentioned purpose of the present invention, feature and advantage will become.
Definition
" high frequency light capacity trace signal ", this term generally are meant 10 hertz to 35 hertz left and right sides light capacity trace signals, but not to this strict qualification, as long as they can make realization the object of the invention.
Below with reference to Fig. 1 to Figure 10 specific embodiments of the present invention are specifically described.
As mentioned above, light capacity trace signal can be represented the beat variation of blood flow in the blood vessel that causes of pulse.The spectral range of general light capacity trace signal is from 0.5 hertz to 35 hertz, but the signal in this spectral range is easy to be subjected to the low frequency movement noise jamming and causes distorted signals.Fig. 1 for same measured under not motion noise situations and have a light capacity trace signal that writes down under the motion noise situations.
Therefore, though the light capacity trace signal that obtains based on the human body physiological parameter measurement requirement of light capacity trace signal under the situation that has the motion noise, also to stablize as much as possible.In the present invention, high frequency light capacity trace signal is used to human body physiological parameter is measured.
Fig. 2 for same measured under not motion noise situations and have a high frequency light capacity trace signal that writes down under the motion noise situations.Therefrom can find out significantly, utilize high frequency light capacity trace signal to reduce because the distorted signals that the low frequency movement noise is caused.Fig. 3 is then for utilizing high frequency light capacity trace signal to measure the flow chart of an embodiment of heart rate method according to the present invention.
Because the AC portion of light capacity trace signal can reflect the cyclically-varying of the beat pulse of user,, just can calculate the heart rate of testee as long as therefore obtain the time in each cycle of this signal.
With reference to figure 3, at first obtain through the input signal of signal amplification with Filtering Processing, i.e. high frequency light capacity trace signal by module 310.Utilize top point detection algorithm, module 320 is determined the time location of the top point of high frequency light capacity trace signal.Then, module 330 utilizes the time difference of the top point of two adjacent high frequency light capacity trace signals to decide the cycle of pulse.Next step, module 340 determines according to the cycle of determined pulse whether detected pulse sum reaches preset value.If satisfy condition, then enter module 350, otherwise enter module 320, reach preset value until detected pulse sum.At last, module 350 is determined the heart rate of user, and shows on module 360.
Fig. 4 is for measuring the structural representation of an embodiment of blood pressure device according to the present invention.
As shown in Figure 4, this blood pressure measuring device comprises: ecg signal acquiring unit 1, light capacity trace signal collecting unit 2, Signal Pretreatment unit 3, microprocessor unit 4, input block 5, wireless data transmission unit 6 and display unit 7.
The electrocardiosignal that ecg signal acquiring unit 1 and light capacity trace signal collecting unit 2 collect and the waveform of light capacity trace signal as shown in Figure 4, wherein, transverse axis is represented the time, longitudinal axis representative voltage.Fig. 4 shows the waveform of its R type ripple that collects, and wherein R has represented the top point of R type ripple.3 pairs of electrocardiosignal and the light capacity trace signals from ecg signal acquiring unit 1 and light capacity trace signal collecting unit 2 in Signal Pretreatment unit carry out pretreatment respectively.
Particularly, the electrocardiosignal pretreatment mainly comprises preposition difference amplification and multiple-stage filtering, and its bandpass filtering frequency is that amplification is about 2000 about the 0.5-40 hertz.The pretreatment of light capacity trace signal mainly comprises high-frequency band pass filtering and amplification, and its spectral range is that amplification is about 500 about the 25-35 hertz.After the filtering amplification, high frequency light capacity trace signal is input to microprocessor unit 4.Microprocessor unit 4:1) to carrying out analog digital conversion through pretreated electrocardiosignal and high frequency light capacity trace signal; 2) detect corresponding reference point on electrocardiosignal and the high frequency light capacity trace signal, calculate the time difference between them; 3) collect the reference pressure value of importing by input block 5, and in calibration mode, calculate the parameter of blood pressure measurement formula; 4), and utilize the blood pressure measurement formula and pulse wave transmission time of recording is in real time calculated systolic pressure and diastolic pressure according to the parameter in the calibration mode meter, calculated; 5) pressure value that will calculate sends display unit 7 to.In addition, wireless data transmission unit 6 is used for blood pressure measurement is transferred to remote terminal.
To those skilled in the art because the realization circuit of said units has been known prior art, by just can ten minutes with reference to existing list of references easily make these unitary circuit such as Chinese patent application 03153805.3 disclosed.Therefore, will further expansion explanation not be done in the realization of these element circuits in this manual.
Fig. 5 is the flow chart of blood pressure measuring method one embodiment according to the present invention.
As shown in Figure 5, this method mainly comprises three processes, that is: calibration process, the process of determining the pulse wave transmission time (being described interval) and the process of calculating blood pressure measurement result.Below will be elaborated respectively to these three steps.
One, calibration process:
Shown in 510 among Fig. 5, the purpose of calibration process is to provide calibration parameter for follow-up blood pressure measurement.Its operating procedure is: at first utilize standard-sphygmomanometer witness mark diastolic pressure and systolic pressure, then above-mentioned two pressure values are input to the microprocessor unit of blood pressure measuring device by keyboard or alternate manner, in order to the parameter of definite blood pressure measurement formula.Fig. 6 has provided the detailed step of calibration process.
With reference to figure 4 and 6, at first, in step 610 and 620, will utilize respectively in the microprocessor 4 that reference systolic pressure that standard-sphygmomanometer measures and diastolic pressure input to blood pressure measuring device.Then, in step 630, the pulse wave transmission time (its detailed step will provide in Fig. 7) between the reference point when determining calibration on electrocardiosignal and the high frequency light capacity trace signal by microprocessor 4 (see figure 4)s.
Here, suppose that the pressure value that is used for calibration process is respectively SBP1_cal, SBP2_cal, DBP1_cal and DBP2_cal (promptly, utilize standard-sphygmomanometer to carry out twice measurement, record two with reference to blood pressure at every turn, SBP1_cal represents the systolic pressure that records for the first time, DBP1_cal represents the diastolic pressure that records for the first time, and the rest may be inferred), be respectively PTT1_cal and PTT2_cal with the above-mentioned twice corresponding pulse wave of blood pressure measurement transmission time.In addition, supposing that the parameter corresponding to systolic pressure blood pressure measurement formula is α s and β s, is α d and β d corresponding to the parameter of diastolic pressure blood pressure measurement formula, and then blood pressure can be expressed as:
SBP1_cal=αs×PTT1_cal+βs
SBP2_cal=αs×PTT2_cal+βs
DBP1_cal=αd×PTT1_cal+βd
DBP2_cal=αs×PTT2_cal+βd
Like this, according to the above-mentioned relation formula, parameter alpha s and β s and α d and β d that just can the calculating blood pressure measure equation in step 640.Then, in step 650, these parameters of determining are stored in the internal memory of microprocessor, calculate for follow-up blood pressure measurement and use.
Two, determine the process in pulse wave transmission time:
Shown in the step 520 among Fig. 5, this process is used for determining the pulse wave transmission time of actual blood pressure measuring process.Fig. 7 has illustrated the step of how determining pulse wave transmission time by high frequency light capacity trace signal and electrocardiosignal.
As shown in Figure 7, at first, in step 710, detect the top point of R type ripple in the electrocardiosignal and write down time location at this moment.Then, in step 720, detect the top point of high frequency light capacity trace signal and write down time location at this moment.Next, in step 730, calculate the pulse wave transmission time, just the interval between the top point of the top point of R type ripple and corresponding high frequency light capacity trace signal in the electrocardiosignal.Corresponding high frequency light capacity trace signal be meant follow closely occur after the R type ripple in the ECG signal high frequency light capacity trace signal.In step 740, calculate the meansigma methods of above-mentioned interval.Why using meansigma methods, is because can be subjected to the interference of many factors in the process of above-mentioned pulse wave transmission time determination, causes certainty of measurement to descend.In the present embodiment, the suggestion user should obtain the measurement data in 10 seconds at least and do on average when carrying out blood pressure measurement.To be transfused to the step 630 that is used for calculating blood pressure or inputs to Fig. 6 to the step 530 among Fig. 5 calibrates device being used for through the pulse wave transmission time numerical value after the average treatment.
Three, the process of calculating blood pressure
Shown in the step 530 among Fig. 5, blood pressure computing formula that this process utilization is determined and pulse wave transmission time, calculate systolic pressure and diastolic pressure respectively in step 510 and 520.Specifically, in this process, in the blood pressure computing formula that microprocessor 4 is updated to the meansigma methods in real-time pulse wave transmission time of recording in the actual blood pressure measuring process in the step 510 to be determined, thereby calculate actual pressure value.Fig. 8 has provided the specific implementation step of this process.
As shown in Figure 8, step 810 is used for calculating systolic pressure by the blood pressure computing formula of the internal memory that is stored in microprocessor 4, and its computing formula is as follows:
Systolic pressure=α s * PTT_ave+ β s
Wherein α s, β s calculate in the step 640 of blood pressure measurement calibration process shown in Figure 6, and PTT_ave is the average pulse ripple transmission time shown in Figure 74 0.
Step 820 is used for calculating diastolic pressure by the blood pressure computing formula in the middle of the internal memory that is stored in microprocessor 4, and its computing formula is as follows:
Diastolic pressure=α d * PTT_ave+ β d
Wherein α d, β d calculate in the step 640 of blood pressure measurement calibration process shown in Figure 6, and PTT_ave is the average pulse ripple transmission time shown in Figure 74 0.
After calculating was finished, result data can further be handled in step 540,, if pressure value surpasses arm's length standard, then will provide warning message, shown in step 550 that is.Further measure if desired, then in step 560 again invocation step 520,530,540 and 550 to repeat said process.
Fig. 9 shows according to a specific embodiments of the present invention, the sketch map of finger ring type cardiotachometer.
As shown in Figure 9, the light that light source 910 sends can be visible light (particularly HONGGUANG and green glow, it is 680 and 530 nanometers that wavelength is about respectively) or infrared light (wavelength is 880 or 940 nanometers).Optical inductor 920 can be photoconductive resistance, light sensitive diode, phototriode and photoelectric crystal.The light of the different wave length that can send according to light source is suitably selected the optical inductor comparatively responsive to this light.
Circuit unit 930 can comprise signal pre-processing circuit, microprocessor, liquid crystal display and wireless data transmission device.They are used for handling and obtain light capacity trace signal by optical inductor 920, obtain high frequency light capacity trace signal, and calculate heart rate with this.By wireless data transmission technology heart rate measurements is transferred to remote terminal, and can accepts feedback information from the central station.
Figure 10 shows a specific embodiments of the present invention, the sketch map of wrist formula wrist-watch sphygomanometer.
Be equipped with a pick off 1010 that comprises light source and optical inductor in this Watchcase front, be used to gather the light capacity trace signal of user; And electrode 1020 that is used to detect electrocardiosignal.The back of table can be used as another electrode (not shown) that detects electrocardiosignal.Label 1050 is a watchband.Table body unit 1030 can comprise signal pre-processing circuit, microprocessor and wireless data transmission device.They are used for handling the electrocardiosignal that light capacity trace signal that optical inductor 1010 obtains and electrocardioelectrode 1020 obtain, and based on theory described above, calculate the pressure value of testee.Liquid crystal display 1040 can show this pressure value.In the present embodiment, can further blood pressure measurement be transferred to remote terminal, and can accept feedback information, thereby realize the real-time continuous monitoring of blood pressure from the central station by wireless data transmission technology.
The present invention sets forth with the above specific embodiment and description.Yet, it should be understood that before not departing from spirit of the present invention to put that those skilled in the art can carry out equivalents and modification to it.Their scope is also included within the appended claim.

Claims (26)

1. a method of obtaining 10 hertz to 35 hertz of left and right sides light capacity trace signals is characterized in that the light capacity trace signal that will obtain from human body amplifies and Filtering Processing.
2. according to the method for claim 1, it is characterized in that described light capacity trace signal is the signal from human body tip tissue sampling.
3. device that utilizes high frequency light capacity trace signal to measure heart rate is characterized in that described device comprises:
The light capacity trace signal collecting unit is used to gather the high frequency light capacity trace signal of human body tip tissue;
Microprocessor unit is handled the high frequency light capacity trace signal that is obtained; And
Display unit shows through microprocessor unit and handles resultant heart rate.
4. according to the device of claim 3, it is characterized in that described light capacity trace signal collecting unit further comprises the Signal Pretreatment unit, the light capacity trace signal that is used for collecting is transformed into high frequency light capacity trace signal.
5. according to the device of claim 3 or 4, it is characterized in that described light capacity trace signal collecting unit comprises the pick off of the light capacity trace signal that is used to gather human body tip tissue.
6. device according to claim 5 is characterized in that the described pick off that is used to detect light capacity trace signal is light emitting diode and light-sensitive element.
7. device according to claim 6 is characterized in that described light-sensitive element is an optical inductor.
8. device according to claim 4 is characterized in that, described Signal Pretreatment unit comprises carry out the circuit of filtering and amplification from the light capacity trace signal of described light capacity trace signal collecting unit.
9. device according to claim 3 is characterized in that, also comprises being used to show the display unit of heart rate and the wireless data transmission unit that is used for heart rate measurements is transferred to remote terminal.
10. device that utilizes high frequency light capacity trace signal to measure blood pressure comprises:
The light capacity trace signal collecting unit is used to gather the high frequency light capacity trace signal of human body tip tissue;
The ecg signal acquiring unit, the electrocardiosignal that is used to gather human body;
The Signal Pretreatment unit, it is electrically connected with described ecg signal acquiring unit and described light capacity trace signal collecting unit, is used for electrocardiosignal and light capacity trace signal from described ecg signal acquiring unit and described light capacity trace signal collecting unit are carried out pretreatment;
Input block is used to import the human blood-pressure reference value;
Microprocessor unit is electrically connected with Signal Pretreatment unit, input block respectively, with described blood pressure reference value with handle through the signal of Signal Pretreatment cell processing, obtain pressure value.
11. according to the device of claim 10, it is characterized in that described light capacity trace signal collecting unit further comprises the Signal Pretreatment unit, the light capacity trace signal that is used for collecting is transformed into high frequency light capacity trace signal.
12., it is characterized in that described light capacity trace signal collecting unit comprises the pick off of the light capacity trace signal that is used to gather human body tip tissue according to the device of claim 10 or 11.
13. device according to claim 12 is characterized in that the described pick off that is used to detect light capacity trace signal is light emitting diode and light-sensitive element.
14. device according to claim 13 is characterized in that described light-sensitive element is an optical inductor.
15. device according to claim 11 is characterized in that, described Signal Pretreatment unit comprises carry out the circuit of filtering and amplification from the light capacity trace signal of described light capacity trace signal collecting unit.
16. device according to claim 10 is characterized in that, also comprises display unit that is used for display of blood pressure and the wireless data transmission unit that is used for blood pressure measurement is transferred to remote terminal.
17. the method for a blood pressure measurement comprises:
A) provide the electrocardiosignal and the high frequency light capacity trace signal of human body;
B) selecting first reference point on the described electrocardiosignal and on described high frequency light capacity trace signal, selecting second reference point;
C) obtain the human pulse ripple transmission time according to described two reference points; And
D) described pulse wave transmission time and human blood-pressure reference value are handled the pressure value that obtains estimating.
18. method according to claim 17 is characterized in that, first reference point on the described electrocardiosignal is the point on the R type ripple in the electrocardiosignal.
19., it is characterized in that second reference point on the described high frequency light capacity trace signal is its top point according to claim 17 or 18 described methods.
20. method according to claim 17 is characterized in that further comprising electrocardiosignal and high frequency light capacity trace signal is carried out analog-to-digital step.
21. method according to claim 17 may further comprise the steps:
A ') utilize the light capacity trace signal collecting unit to gather the light capacity trace signal of human body tip tissue;
B ') utilize the ecg signal acquiring unit to gather the electrocardiosignal of human body;
C ') utilizes microprocessor unit selecting reference point on the described electrocardiosignal, on described high frequency light capacity trace signal, selecting first, second reference point respectively, and calculate the time of pulse wave transmission according to described two reference points; And
D ') utilizes the blood pressure measurement formula preserved in the described microprocessor module according to the described pulse wave transmission time, determine pressure value.
22. method according to claim 21 is characterized in that, described steps d ') further comprise:
D '-1) utilizes the reference pressure value of input block input and measuring the described pulse wave transmission time measured during with reference to blood pressure, obtain described blood pressure measurement formula and be kept in the described microprocessor unit; And
D '-2) utilize the pulse wave transmission time that obtains in real time to determine pressure value according to described blood pressure measurement formula.
23. method according to claim 22 is characterized in that, described blood pressure measurement formula is 1 time or 2 regression equations.
24. method according to claim 22 is characterized in that, described step c ') further comprise the step that the pulse wave transmission time is averaged.
25. method according to claim 24 is characterized in that, the meansigma methods in described pulse wave transmission time is the meansigma methods of the data of record in 10 seconds.
26. method according to claim 21 is characterized in that also comprising the step of utilizing wireless data transmission unit the pressure value that records to be sent to remote terminal.
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