CN1704018A - Method and device for measuring sense and physiological parameter based on computer - Google Patents

Abstract

The invention relates to a multiple-part, hardware and software system of computer or internet which is used to estimate sensory and physiological parameter. Hardware/software array can comprise three parts used to estimate visual field, aural function and heart/cardiovascular and vegetative nervous system parameters.

Description

Be used to estimate to feel computer-based method and equipment with physiological parameter

Technical field

Present invention relates in general to physical examination and medical diagnosis, and be specifically related to be used to estimate to feel and the improving one's methods and equipment of physiological parameter.

Background technology

Prior art can not fully solve the defective of some hygienic measuress, such as being used for detecting preventing the Sexual health inspection and being used for low service quality crowd's (underserved populations) physical examination of study defective (learning deficiency).For example, because need to use a lot of medical experts' expensive method, the early stage hygienic measures in the school checks that current is inadequate.Just made laws and in all provided schools, carried out the whole country test, monitored student's school work performance, but also do not provide and learnt the inspection of the physiological function that defective is associated.

Suitable physical examination is very important, so the expert proposes to carry out following annual checkout: be born by 10 years old: cardiovascular, vision and audition; 11-64 year: cardiovascular and vision: and more than 64 years old: cardiovascular, vision and audition.

Aforementioned discussion has reflected the state of the current techniques that the present invention should be noted that.The reference of this information and discussion are easy to help to fulfil the honest responsibility of informing of applicant, the open information that is associated with the examination of claim of the present invention.But, be appreciated that any prior art list of references does not all have all to disclose alone or in combination, instruction is proposed, show or otherwise publicity the present invention with prescription is here described.

Summary of the invention

The invention provides the hardware and software system of a plurality of parts, be used to use stand-alone computer and/or estimate sensation and physiological parameter by the Internet.The present invention allows the clinician, and educator or family user are collected the critical data about physiology and mental health, and the situation of health and emotion according to a preliminary estimate.Application of the present invention is included in treatment and gets involved preceding estimated pressure rank, the reflection of monitored patient to handling or treating, and strengthen the study probability.The user can be with the data storage collected in user's oneself computer hardware driver, perhaps data are collected in the central computer data base, storage and management, perhaps data are sent to the third party, such as hospital or HMO, all are all by using computer network and the data transmission technology that oneself knows in the prior art to realize.

For the estimation visual field, auditory function and heart and vegetative nervous system (ANS) parameter, hardware may comprise three ingredients.The visual field is checked that ingredient comprises and is used to measure the visual range parameter interaction software of (comprising binocular vision, achromatopsia, contrast sensitivity and blind spot size).This software is attended by the hardware ingredient, and the hardware ingredient comprises that permission supports and stablize the shelf of head when estimating, and the device that is used for covering respectively each glasses.The audition ingredient comprises software that is used to test auditory function (for example, detecting sound frequency) and the hardware that comprises the simple earphone that inserts computer.The heart of this assembly and ANS ingredient comprise the instrument that is tied or otherwise is applied to health (for example, be banded on the finger, or append to instrument on the ear) and be inserted into computer, add the software that reads from instrument and explain physiological parameter.These parameters may comprise that these functions comprise pulse rate about the scope of the data of heart and ANS function, heart rate variability (heartrate variability), and galvanic skin response.

Notion of the present invention can be used in the operation of commerce to commerce, for example, make the client who is used for being used for them by the Internet health or educational institution, can also be used in commercial version to client, the common user of the Internet can monitor themselves or they kinsfolk's physiology or sensorineural measurement by it.Independent user or tissue can pass through the age, sex, or the Internet application is set according to specific needs (for example, strengthen motion or strengthen education).The Internet is used can be used for being user's printed report, and report is sent to their health or education expert, or is stored in reference or the comparison that is used for future in the online database.

From below in conjunction with can more being expressly understood other novel feature of the present invention and characteristic the description of accompanying drawing, the structure of operation and method, and other purpose and advantage, the mode with example shows the preferred embodiments of the present invention in the accompanying drawings.But, should be expressly understood very much, accompanying drawing and to describe only be illustrative, and be not intended to the present invention is made qualification.By pointing out multiple novel feature of the present invention and characteristic in claims and these disclosed other parts.The present invention and be not only in these features single any one, but be used for the combination of the structure of their all specific functions.

In order to understand following detailed better, and, summarized even more important feature of the present invention widely in order to approve the contribution of the present invention better to prior art.Certainly, will describe additional features of the present invention hereinafter, and it can form the other theme of claims.Those of ordinary skills it will be appreciated that, based on change of the present invention can other realizes the structure of purposes more of the present invention, the basis of method and system as design at an easy rate.Therefore, do not break away under the situation of the spirit and scope of the present invention, think that claim comprises that the structure of this equivalence is very important at it.

In addition, the purpose of summary is to make the United States Patent and Trademark Office and the general public, and scientist particularly, engineer and the application person who is unfamiliar with the present technique of this patent or law term or word can determine the application's disclosed characteristic of technology and essence fast from rough reading.Summary is not intended to definition the application's invention, and the present invention is stipulated by claim, also is not intended to and limits scope of the present invention in any way.

May use specific term and etymology to be used for the convenience of reference in the following description, but it is not determinate.For example, unless stated otherwise, such as " making progress ", " downwards ", " left side " and " right side " refers to the direction of making reference in the accompanying drawing.Similarly, such as " inwardly " and " outwards " refer to respectively towards or away from instrument or zone with and the geometric center of specified portions.Unless stated otherwise, the use of single tense comprises plural number, and vice versa.

Description of drawings

By the reference following detailed description, can more clearly understand the present invention except top purpose described.This description will be with reference to the accompanying drawings, wherein:

Fig. 1 is the sketch map of equipment of the present invention, shows the head support frame when the experience vision parameter is estimated, and integrated audition is with heart/ANS ingredient and be connected; With

Fig. 2 is the sketch map of auditory function estimating apparatus of the present invention, and vision and heart/ANS hardware is set in a similar fashion.

The specific embodiment

Fig. 1 is the sketch map of equipment of the present invention, shows to be used for supporting when the experience vision parameter is estimated and stablizing user's head and keep the holder part 10 of user's head to the correct distance of monitor or screen.Support section 10 can comprise pedestal 12, the axle 14 of height-adjustable, and lower jaw lay down location 16.Can in estimating, use vision parameter eyeshield 18 and lens 20.Can use audio frequency to connect 22 interconnect earphone and computer/CPU (not shown)s.Heart/ANS pick off 24 can be integrated into holder part 10, perhaps be connected by holder part with computer/CPU just to convenient.

Fig. 2 is the sketch map of auditory function estimating apparatus 30 of the present invention.Equipment 30 can comprise with earphone 34 interconnection, have the professional control 36 and the patient control 38 audio frequency control box 32.Audio frequency control 32 can be connected by USB connector 42 or Other Instruments with computer/CPU 40.The visual field can be set in a similar manner to be connected with computer with heart/ANS hardware and with it.

Equipment of the present invention comprises three kinds of technology that have been used to detect the stand-alone application of health risk.At first, by with two or more in these ingredients by computer packing and/or use the Internet, the invention provides low-cost and physical examination widely and reporting system.The supervision ingredient is:

Visual field-estimation a plurality of may and diabetic retinopathy (diabetic retinopathy), degeneration of macula (macular degeneration), hue discrimination, heterophoria (phoria), contrast sensitivity, the key visual function that eye movement and other vision situation are associated.

Auditory function-by using the hearing test method assessment audible representation of a plurality of complexity.

Heart and ANS-monitor the cardiovascular and neurovegetative parameter of some omens, and it may be with absent minded, depression, hypertonicity and pressure correlation connection.

This group hardware bundle comprises the device of three cheapnesss: (1) is used for the lower jaw lobby and the eyeshield of visual field test, and (2) are used for the earphone of auditory function, and (3) are used for the infrared sensor of heart and ANS parameter.

The health monitoring group of this three part provides the prediction clinical effectiveness and the reproducible data of early time treatment value is provided.It can provide the earlier detection of some diseases process, monitors some drug side effectes, and helps the management chronic disease.These interactive checking tools provide physiological measurements user-friendly, noninvasive.Clinicist and educator can be in these data of collection arbitrarily and on the computer that the Internet is connected.The result of these tests is sent to selected expert by network be used for further analysis.

The needs that write down privacy standard according to the patient solve privacy concern.Up to the present, such as the coding of password and postcode, rather than name, address and telephone number, can guarantee the safety of all personal data.Health care and Education Specialist Or Specialist In Education can be chosen in their hard disk drive storage data or manage with the data transmission and by the third party.

By advance payment that uses a computer (advances) and the Internet, realize these tasks with cost much lower concerning professional and patient, task (originally only by in the doctor of the center of inconvenience and expensive expert's execution) is checked in monitoring group that the present invention is connected with the Internet reorganization (retool) hygienic measures.

The present invention allows to analyze the interaction between multiple physiological system.This interaction analysis can provide the early warning of specified disease.For example, the police has audition relevant with occupational stress and/or visual problem usually; Early stage Alzheimer (Alzheimer ' s disease) patient has eye usually and follows the tracks of and a vegetative nervous system disease; And the heart rate variability of difference may reduce with the visual field, center and/or diabetes are associated.

The hardware that needs is cheap, and can be used repeatedly by one or more people.Some tests do not need hardware, the building block that perhaps uses most of professionals to possess.

The professional may select to monitor the combination of building block and sub-building block, its setting that is suitable for defining (for example, industry, education, medical science, physiological setting).Similarly, the user can be according to the age, and sex or specific needs (for example, physical culture technical ability, pressure monitor and management) are provided with the monitoring group.

The estimation of visual field can be realized such as the EnVision that can buy the interactive medical system that obtains from the Biotechtronics of San Francisco (California, San Francisco) by available program.This program is a visual inspection tool group comprehensive and innovation, can be used for moving the IBM-compatible personal computer of Microsoft's Window operating system.This subjectoscope can move in fixed office or in the field portable environment.Ideal is used for sanatorium, healthy fair, school, farm usefulness, clinical study, family monitoring, hospital, and be suitable for optometrist as the quick check instrument, ophthalmologists or even pediatrician's office.

All detectors may comprise simple case control's device, are used for storage and follow the tracks of patient data, and may further include the detector that is used for following zone:

Be used for far away and near static resolution (for example, this grand letter (Sloan-like letters) of class, crooked E and pictograph);

Binocular vision (heterophoria of vertical and level, vergence (Vergences));

Central field distortion (class Amsler vibraphone grid (Amsler-like grids)) with customization of symbol on the screen;

Achromatopsia/color weakness (pseudo-same colour disk (pseudoisochromatic plates) and class farmsworthD:5):

In aroused in interest and blind spot shine upon (class tangent screen detector);

Contrast sensitivity (gray scale and color contrast inspection);

Dynamic resolution (mobile letter/figure);

Visual movement (sweep fast and catch up with); And

Adapt (standard scale).

Use single icon and drop-down menu to control detector.Design them to such an extent that be easy to use, and can be provided with fully, thereby allow the user to finish all aspects of control operation.Each detector can move under simple automatic mode, perhaps can manually move.Automatic mode is with the complete inspection of command prompt operation.Manual mode allows the whole aspects of user with program, such as color setting, demonstration selection etc., the arbitrary portion (for example only checking left eye) of control ground rolling inspection fully.Manual mode allows detector can move fast under the situation of those special care reviews time.Complete form with figure helps (Windows HELP) menu group to can be used for all aspects of program.For all detectors provide consistent user interface.

Detector can be managed by ophthalmologist or assistant, perhaps if necessary, and can be with less direction self management.Like this, be responsible for, detector can be used to the domestic monitoring of the situation that worsens by suitable medical treatment.

EnVision comprises the main menu that is used for starting independent detector and is included in the systemic-function in all versions (case control's device, monitoring is provided with, and helps).

Static resolution: use this grand letter of class, comprise the resolving power of nearly (24 inches) and (1O foot) far away.For accurate nearly resolving power inspection (below 20/40),, use Graphics matching because can not show computer font accurately to little letter.Select 24 " and 10 ' distance obtain to be used for the optimization computation machine check of resolving power.

Central field distortion detector uses class Amsler vibraphone barrier and some other draughtsmanships (point, diagonal, and combination) to determine any central field distortion or scoromas.Can be at an easy rate with mouse with the degeneration of macula figure on the symbolic representation screen.

The color weakness detector is a class D15 color detection, and expression can be used for the most complicated detector of P.C.Except the colour of solution of operative norm, can use the color instrument of the innovation that includes each colour of solution bag to create the colour of solution colour table of customization at an easy rate.This makes the colour of solution device become multi-functional instrument, can check special color problem.For example, if find green color weakness, where the color slider that can be easy to create customization is looked at problem mainly is positioned at green spectral.

The version of all subjectoscopes comprises that simple case control data base stores permanent patient record and check result, be used for reference in the future and with new inspection relatively.

Contrast sensitivity provides extremely low gray level of cost and the inspection of color contrast sensitivity.

Envision has some functions:

1. static vision resolving power: allow individuality or group determine those checked people's resolving power, and allow monitoring to change.This is the most useful for child and old man.

2. binocular vision inspection: this provides about having the study defective, head injury, the people of hypomotility and paralytic's information.This detector provides the information of fixation system aspect the ability of catching target or moving with proper speed and time in the space.

3. visual field, center: or the Amsler vibraphone barrier.This test is to allow the value of any people's central monitoring position vision loss or distortion.It also is those critical patients because degeneration of macula, diabetic retinopathy, or centre bore and the much retinal hemorrhage that brings of other speckle disease and the value of the central field loss that causes.

4. achromatopsia test: this test is available the most responsive color test except 100 tests that only are used to study.It in inspection work color weakness and aspect the sensitivity of certain drug treating, all be valuable.

5. field aroused in interest in: the visual field helps to obtain field loss after apoplexy or closure injury of head.Some researchs are thought can be by field research diagnosis depression and anxiety.Can find the difference of field loss section omission (verses neglect) and find the pressure that causes field loss.Blind spot research can illustrate multiple disease, although herein instrument inadequately sensitivity be used to measure these diseases.The use of resonance also is good.

6. vision mobility: can be in study detect tracking problem in the disabled and injury of head.Studies show that, in Alzheimer and other nerve defective that mainly in the old people, takes place, have the early stage defective of following the tracks of.

7. adapt: this defect area shows in the injury of head of being everlasting, youngster particularly, and study is disabled, and the vision that takes place after a few hours that use a computer repeats pressurized disease (ORSS),

8. dynamic resolution: this is the detector that is used for the athlete.

9. contrast sensitivity: this is at the closure injury of head, cataract, and multiple sclerosis, for glare problem, and the visual quality in some other neural visual performance disorders provides the inspection of information.

Audio-frequency function estimates and may be realized by AudioVision that it is can buy the audio frequency harmonious sounds that obtains from the Biotechtronics of San Francisco (California, San Francisco) to learn a skill.AudioVision comprises the system that can manage hearing test that makes, makes to measure to be divided into whole frequency range octave, that ear can respond.The client can set up the frequency range of his hearing test response.Automatically perform affirmation.In case process finishes, the result is stored among the data base with audition.

54 frequencies that produce are based on the part of a series of nine minutes octaves note " C ", from 32Hz to 16384Hz.The selection of these frequencies extends beyond 9 octaves, makes to carry out standard or complicated hearing test.Can from setup menu, select the frequency used: with octave: 1/2 octave; 1/3 octave; Hearing test with 1/16 octave; The standard audible test of frequency of utilization 128-256-512-724-1024-1448-2048-2896-4096-5793-8192-11585; And specific audiometrist program.

Feature functionality comprises automatic audiometry, wherein tests from low-limit frequency to begin and finish to highest frequency.Client is controlled sound level with stick, and pushes call button when arriving the perception limit.In semi-automatic audiometrist, by two control stick control audiometrists, one is used for Therapist/operator, and another is used for client.Sound is constant, pulsation, or synthetic amplitude.In manual audiometrist, control test and sound level by Therapist/operator fully.

Heart and ANS estimate and can be realized by the CardioVision program of Biocommunication company that it can obtain from the Biotechtronics of San Francisco (California, San Francisco).The heart rate variability analysis system of program is the clinical tool case, provides doctor physician and health professional to use complicated heart rate variability analysis to draft the system easily of protocol and measurement result.System adopts advanced software platform technology, allows to continue monitoring and measures " in real time " physiological signal.It is non-evading (non-evasive), intuition, the software and hardware system that is easy to use monitoring and measures heart rate variability.Heart rate variability (HRV) and heart rate are important measurements, by its state of human organ as can be seen, and provide accurate message about the vegetative nervous system function.Software is dynamic, and by " plug and play " electric cardiography (cardiographic) (ECG) or (PPG) technical operation of photoelectricity plethysmography (Photoplethesmographic).

Heart rate variability is measured the reaction of heart to the pressure of any type.When by frequency and time series analysis heart rate being analyzed, some important features will display.By ingredient of the strong control of parasympathetic nervous system, breathing causes sinus arrhythmia (RSA), and mediates by breathing.Parasympathetic activity has short response time (2 to 5 seconds) usually and therefore can observe with the arrowband changes in heart rate in high-frequency range.Sympathetic nerve and parasympathetic activity are reflected among the intermediate frequency HRV (7 to 15 seconds), and main sympathetic activity (＞20 seconds) reflects in low-down frequency range.When making the analysis of mathematics ground, these variablees are represented the quantification multidimensional measure of vegetalitas activity and cardiac function.The present invention includes the complete system of measuring and monitoring these parameters.

Some researchs will be associated with the improvement of health and physiological signs in the positive change (increase) in the overall heart rate variability.In cardiovascular disease, SIDS, depression, cardiac sudden death, drug dependence, entire life, anorexia nervosa, diabetes, and the role of the heart rate variability in anxiety/fear expands to the understanding to these diseases.These new information allow the more effective invention of exploitation, help doctor physician and health professional to determine quantitatively whether their processing is effective, and the new measurement of vital functions is provided.The invention provides for predicting and prevent vegetative nervous system and the very important data of cardiovascular disease in the future.

Heart and ANS estimate may further include the analysis of APG (acceleration plethysmogram), and it is the second dervative of PTG (plethysmogram).Pulse is the variation of the pressure propagated from heartbeat and by vein.Pulse changes down at the state of systaltic energy and circulation (aorta, tremulous pulse, capillary tube), and reflects sanguimotor state.By the thinner waveform of division is shown, the analysis meeting of measurement result is easier.From the APG ripple, can estimate following some or all: heart intensity, blood vessel elasticity, the residue blood volume, vessel arms elasticity, blood vessel aging, kinemic relation, hypertension, arteriosclerosis, the heart official can, arrhythmia, heart failure, cardiac output, autonomic nerve disorder, and the effect of heart tonic or other Therapeutic Method and multiple excitation.

Feature functionality comprises: fully free, draft independent protocol fast and easily; The real-time measurement of heart rate variability; Power spectral-density analysis is distinguished the adjusting interaction of sympathetic nerve and parasympathetic nervous system; Accurate and intelligible reading based on the heart rate variability of testing; Very low, low and high-frequency than number and ratio; Describe neurovegetative balance or unbalanced bar diagram and analysis of spectrum; By the accurate online analysis of spectrum of velocity chart to heart rate; Accurately reading of per minute pulse and pulse interbody spacer; The analysis report that comprises figure, harmony in the exterior narration; Be used for color graphics and display screen and wieldy window pattern; Be easy to install, the technology of plug and play; And skin electroresponse monitoring.

Therefore, the invention is characterized in, physical examination and reporting system (equipment) based on software, it has one or more visual fields and checks, auditory function is checked, and heart and vegetative nervous system parameter testing, wherein handles check result by stand-alone computer and (may directly be written into software, or from the global computer network downloaded software), and/or be sent to remote equipment by global computer network.In addition, feature of the present invention also is, be used for physical examination and method of reporting, comprise that being provided for one or more visual fields checks, auditory function is checked, and the device of heart and vegetative nervous system parameter testing, and handle the data on stand-alone computer and/or check result is sent to remote equipment by global computer network.

Above-mentioned openly being enough to makes those of ordinary skills realize the present invention, and the inventor is provided the current best realization pattern of the present invention that can expect.Though here provide the preferred embodiment of the present invention fully and complete open, should not limit the invention to specific structure, spatial relationship, and shown in described operation.For those of ordinary skills, under the situation that does not break away from true spirit of the present invention and scope, can make multiple change, alternate structure, and variation and equivalent.This variation may comprise other material, building block, structural configuration, size, shape, form, function, performance characteristic etc.

Therefore, above-mentioned explanation and diagram should not be understood that to limit scope of the present invention, and scope of the present invention only is defined by the following claims.

Claims (17)

1. physical examination and reporting system based on a software, described system comprises:

Testing fixture is selected from the group that comprises visual field inspection, auditory function inspection and heart and vegetative nervous system parameter testing, and wherein, the result of described inspection is handled by computer.

2. physical examination as claimed in claim 1 and reporting system wherein, send to remote equipment with described check result by global computer network.

3. physical examination as claimed in claim 1 and reporting system, wherein, the described device that is used for checking the visual field comprises the device that is used to measure a plurality of vision parameters.

4. physical examination as claimed in claim 3 and reporting system, wherein, described vision parameter comprises binocular vision.

5. physical examination as claimed in claim 3 and reporting system, wherein, described vision parameter comprises achromatopsia.

6. physical examination as claimed in claim 3 and reporting system, wherein, described vision parameter comprises contrast sensitivity.

7. physical examination as claimed in claim 3 and reporting system, wherein, described vision parameter comprises the blind spot size.

8. physical examination as claimed in claim 1 and reporting system, wherein, the described device that is used for the auditory function inspection comprises the instrument that is used to test to the detection of sound frequency.

9. physical examination as claimed in claim 1 and reporting system, wherein, described heart and vegetative nervous system parameter comprise pulse rate.

10. physical examination as claimed in claim 1 and reporting system, wherein, described heart and vegetative nervous system parameter comprise heart rate variability.

11. physical examination as claimed in claim 1 and reporting system, wherein, described heart and vegetative nervous system parameter comprise APG.

12. physical examination as claimed in claim 1 and reporting system, wherein, described heart and vegetative nervous system parameter comprise the skin electroresponse.

13. physical examination as claimed in claim 1 and reporting system, wherein, described heart and vegetative nervous system parameter are diagnosis and the predictions to ATHD.

14. physical examination as claimed in claim 1 and reporting system, wherein, described heart and vegetative nervous system parameter are diagnosis and the predictions to depression.

15. physical examination as claimed in claim 1 and reporting system, wherein, described heart and vegetative nervous system parameter are to hypertensive diagnosis and prediction.

16. physical examination as claimed in claim 1 and reporting system, wherein, described heart and vegetative nervous system parameter are diagnosis and the predictions to psychentonia.

17. one kind is used for physical examination and method of reporting, described method comprises following step:

Be provided for the device that the visual field is checked;

Be provided for the device that auditory function is checked;

Be provided for the device of heart and vegetative nervous system parameter testing; With

The result of described inspection is sent to remote equipment by global computer network.