CN1680321A - Preparation of miglitol - Google Patents
Preparation of miglitol Download PDFInfo
- Publication number
- CN1680321A CN1680321A CN 200510037675 CN200510037675A CN1680321A CN 1680321 A CN1680321 A CN 1680321A CN 200510037675 CN200510037675 CN 200510037675 CN 200510037675 A CN200510037675 A CN 200510037675A CN 1680321 A CN1680321 A CN 1680321A
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- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
Description
Formula II | Formula III | Reaction times | Yield | Specific optical rotation (ethyl acetate) |
????X=Cl | ?Z=CN;Z`=COOEt | ????6h | ??55% | ????-27.8° |
????X=Br | ?Z=CN;Z`=COOEt | ????4h | ??68% | ????-28.4° |
????X=Cl | ?Z=Z`=CN | ????6h | ??75% | ????-28.5° |
????X=Br | ?Z=Z`=CN | ????6h | ??83% | ????-27.9° |
????X=Cl | ?Z=Z`=COOEt | ????8h | ??43% | ????-23.6° |
Claims (1)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CNB2005100376754A CN1324010C (en) | 2005-01-12 | 2005-01-12 | Preparation of miglitol |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CNB2005100376754A CN1324010C (en) | 2005-01-12 | 2005-01-12 | Preparation of miglitol |
Publications (2)
Publication Number | Publication Date |
---|---|
CN1680321A true CN1680321A (en) | 2005-10-12 |
CN1324010C CN1324010C (en) | 2007-07-04 |
Family
ID=35067162
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CNB2005100376754A Expired - Fee Related CN1324010C (en) | 2005-01-12 | 2005-01-12 | Preparation of miglitol |
Country Status (1)
Country | Link |
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CN (1) | CN1324010C (en) |
Cited By (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN100441570C (en) * | 2006-05-24 | 2008-12-10 | 严洁 | Preparation of mitiglinide calcium and its quality control method |
CN102382033A (en) * | 2010-08-31 | 2012-03-21 | 凯瑞斯德生化(苏州)有限公司 | Preparation methods for optical activity mitiglinide ester and mitiglinide salt |
CN104693109A (en) * | 2013-12-05 | 2015-06-10 | 陕西师范大学 | A preparing method of a miglitol intermediate |
CN102911107B (en) * | 2012-09-28 | 2015-11-25 | 迪沙药业集团有限公司 | The preparation method of S 21403 |
CN107879927A (en) * | 2017-11-17 | 2018-04-06 | 中国药科大学 | A kind of method for preparing α chlorinated carboxylic acids |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU654331B2 (en) * | 1991-03-30 | 1994-11-03 | Kissei Pharmaceutical Co. Ltd. | Succinic acid compounds |
FR2765578B1 (en) * | 1997-07-03 | 1999-09-10 | Adir | PROCESS FOR THE PREPARATION OF A SUBSTITUTED PERHYDROISOINDOLE |
FR2805535B1 (en) * | 2000-02-25 | 2002-04-12 | Adir | NEW PROCESS FOR THE PREPARATION OF ISOINDOLINE |
WO2003062186A1 (en) * | 2002-01-22 | 2003-07-31 | Kissei Pharmaceutical Co., Ltd. | Metal salts of (3s)-3-methoxycarbonyl-4-phenylbutyric acid and usage thereof |
CN100506794C (en) * | 2003-11-13 | 2009-07-01 | 中国科学院上海药物研究所 | New method for preparing medicine mitiglinide for treating diabetes |
-
2005
- 2005-01-12 CN CNB2005100376754A patent/CN1324010C/en not_active Expired - Fee Related
Cited By (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN100441570C (en) * | 2006-05-24 | 2008-12-10 | 严洁 | Preparation of mitiglinide calcium and its quality control method |
CN102382033A (en) * | 2010-08-31 | 2012-03-21 | 凯瑞斯德生化(苏州)有限公司 | Preparation methods for optical activity mitiglinide ester and mitiglinide salt |
CN102382033B (en) * | 2010-08-31 | 2013-04-03 | 凯瑞斯德生化(苏州)有限公司 | Preparation methods for optical activity mitiglinide ester and mitiglinide salt |
CN102911107B (en) * | 2012-09-28 | 2015-11-25 | 迪沙药业集团有限公司 | The preparation method of S 21403 |
CN104693109A (en) * | 2013-12-05 | 2015-06-10 | 陕西师范大学 | A preparing method of a miglitol intermediate |
CN107879927A (en) * | 2017-11-17 | 2018-04-06 | 中国药科大学 | A kind of method for preparing α chlorinated carboxylic acids |
Also Published As
Publication number | Publication date |
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CN1324010C (en) | 2007-07-04 |
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Legal Events
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C06 | Publication | ||
PB01 | Publication | ||
C10 | Entry into substantive examination | ||
SE01 | Entry into force of request for substantive examination | ||
C14 | Grant of patent or utility model | ||
GR01 | Patent grant | ||
ASS | Succession or assignment of patent right |
Owner name: JIANGSU PROVINCIAL INSTITUTE OF MATERIA MEDICA CO. Free format text: FORMER OWNER: JIANGSU PROVINCIAL INSTITUTE OF MATERIA MEDICA Effective date: 20101224 |
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C41 | Transfer of patent application or patent right or utility model | ||
TR01 | Transfer of patent right |
Effective date of registration: 20101224 Address after: 210009, Ma 26 street, Xuanwu Gate, Jiangsu, Nanjing Patentee after: Jiangsu Provincial Institute of Materia Medica Co., Ltd. Address before: 210009, Ma 26 street, Xuanwu Gate, Jiangsu, Nanjing Patentee before: Jiangsu Provincial Institute of Materia Medica |
|
EE01 | Entry into force of recordation of patent licensing contract |
Assignee: Changzhou Tianhua Pharmaceutical Co., Ltd. Assignor: Jiangsu Provincial Institute of Materia Medica Co., Ltd. Contract record no.: 2011320000025 Denomination of invention: Preparation of miglitol Granted publication date: 20070704 License type: Exclusive License Open date: 20051012 Record date: 20110127 |
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C17 | Cessation of patent right | ||
CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20070704 Termination date: 20120112 |