CN1647789A - Method for optimum pressure application and release time for automatic tracking and regulating external counter pulsation device - Google Patents

Method for optimum pressure application and release time for automatic tracking and regulating external counter pulsation device Download PDF

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Publication number
CN1647789A
CN1647789A CN 200510033145 CN200510033145A CN1647789A CN 1647789 A CN1647789 A CN 1647789A CN 200510033145 CN200510033145 CN 200510033145 CN 200510033145 A CN200510033145 A CN 200510033145A CN 1647789 A CN1647789 A CN 1647789A
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Prior art keywords
time
release pressure
release
apply
fighting
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CN 200510033145
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李锡昌
马俊
陈占林
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LIQIANG ELECTROMECHANICAL EQUIPMENT CO Ltd FOSHAN CITY
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LIQIANG ELECTROMECHANICAL EQUIPMENT CO Ltd FOSHAN CITY
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Abstract

The present invention discloses a method of automatically seeking, tracking and regulating optimal pressure applying and releasing time for external counterpulsation device. The method includes acquiring body's vena digitalis signal, calculating the ratio values D/Sp and D/Sa during counterpulsation, obtaining the optimal pressure applying and releasing time via continuous regulation, and obtaining accurate pressure applying and releasing time via continuous counterpulsation. The present invention determines the optimal pressure applying and releasing time via seeking the maximum D/Sp and D/Sa values, and is simple, direct and reliable, and has the advantages of automatically seeking, tracking and regulating optimal pressure applying and releasing time for external counterpulsation device.

Description

Adjust the external counterpulsation unit optimum pressure from motion tracking and apply method with release time
Technical field:
The present invention relates to the use and the control method of external counterpulsation apparatus.
Background technology:
It is to push positions such as the lower limb of human body and buttocks with the frequency identical with heartbeat in a certain moment of diastole that existing external counterpulsation unit uses, backflow with accelerate blood, treat some disease of human body by a kind of like this mode, and can be to select in the segment limit after the diastole particular safety time of generally acknowledging the opportunity of pushing, and in this segment limit, must have the starting point of pushing an of the best, and this best push starting point for being different under different people, the different health.People have invented to adopt and have adjusted pressure and apply and discharge () method for example: inflation and aerofluxus, optimum pressing time when determining counter fighting by dynamic programming algorithm is arranged, as application number is 97112592, the applying date is on June 28th, 1997, denomination of invention is the method for determining the optimum pressing time in the external counterpulsation process and the patent application of adopting the external counterpulsation apparatus of this method, belong to external counterpulsation control technology field, it is to detect in real time on the basis of electrocardiosignal QRS complex at small wave converting method, adopt the control method of optimum pressing time when determining counter fighting, it is by real-time detection QRS ripple, determine critical point, set up evaluation index, optimum pressing time is asked in dynamic programming, implementing counter five steps of process of fighting forms.Concrete steps are: [1] detects the position of QRS ripple in real time, its concrete steps are as follows: 1. extract electrocardiographicdigital digital signals, adopt a bit for per 5 milliseconds, can select 750 points, with the Mallat algorithm this signal is carried out wavelet transformation, obtain the small echo output sequence, get the small echo output sequence under the high-resolution on 3 yardsticks; 2. ask slope threshold value s and distance threshold d, be specially: suppose that 750 points have three cycles, find the maximum-minimum in these three cycles right earlier, half of getting this three positive maximums-negative minimum slope meansigma methods is as slope threshold value s, and three segment distance meansigma methodss are as distance threshold d; 3. real-time process begins, and gets before adopting a bit at 15 and supplies and carry out conversion; 4. on 3 yardsticks, 16 points behind wavelet transformation are begun to judge whether successively to be maximum value or minimum value from last point; 5. after finding maximum, remember that its position is m, its value is B; After finding minimum, remember that its position is n, its value is A, if | m-n|<d+s, calculate its slope: SR=|B--1-A/m-n| wherein, SR is a slope; 6. if SR<s, then the null value between m and the n is the R ripple position of QRS ripple, otherwise, take off a signaling point, repeat 1., 2., 3., 4., 5. process; [2] detecting on the basis of R ripple position in real time, determine critical point; [3] anti-function assessment index J=∫ ↓ [Tg] that fight ↑ [ta] P (t) dt+ ∫ ↓ [ta] ↑ [T] P (t) dt wherein in foundation, J is the cardiovascular blood flow, and ta is the pressurization zero-time, and Ts is the critical point of systolic pressure and diastolic pressure, T is a cardiac cycle, and P (t) is the pulse pressure value; [4] respectively to shank, thigh, buttocks and unite the anti-test of fighting, according to different separately pressurization zero-time ta ↑ [(1)], ta ↑ [(2)], ta ↑ [(3)] of shank, thigh and buttocks that are provided with, write down the pulse pressure value after their counter fighting, then according to the above-mentioned anti-function assessment index of fighting, adopt dynamic programming algorithm, optimum ta ↑ [(1)] pressing time, ta ↑ [(2)], ta ↑ [(3)] during counter being fought; [5] according to the R ripple position and the optimum pressing time of QRS ripple, implement the counter in real time process of fighting.The device that it adopted is gathered electrocardio (pulse pressure) signal by sample circuit, passes to computer behind amplifying circuit, A/D converter, and computer sends instructions to the air bag controlled circuit, the electromagnetic valve that driving and air pump link to each other with air bag, the directly anti-process of fighting of control.
The method only is to determine the anti-function assessment index of fighting according to the cardiovascular blood flow, adopts dynamic programming algorithm to determine optimum pressing time then, as shown in Figure 1.Optimum pressing time of the result that this method obtains is not accurate enough, and can not reflect the anti-effect of fighting of human body exactly.
Summary of the invention:
The objective of the invention is to solve above-mentioned deficiency, and provide a kind of simple and reliable, searching automatically, adjustment apply and the release pressure time method.When using external counterpulsation apparatus, can human body be applied and release pressure from motion tracking, searching Best Times.
The present invention realizes by following technical proposals:
Its method step is:
(1) at the diastole of generally acknowledging, particular safety in paradoxical expansion particular safety time scope during this period of time in the past, is set exert pressure a time Inf (0) and a release pressure time D ef (0) after the time;
(2) fight to patient is counter according to the Inf (0) and the Def (0) that set, collection refers to arteries and veins (or temporo tremulous pulse or ear arteries and veins) signal, calculate contraction wave peak value (S point) and diastolic wave peak value (D point), calculate the ratio of D/Sp (0), the flex point that forwards the diastole crest with the contraction crest to is a separation, draw contraction wave peak area and diastolic wave peak area, calculate the ratio of D/Sa (0);
(3) be Inf (1) and release pressure time to be that Def (1) fights to patient is counter by the interval adjustment time of setting of exerting pressure, draw the ratio of another D/Sp (1) and D/Sa (1);
(4) repeating step 3, constantly adjust apply with the release pressure time be that Inf (n) and Def (n) fight to patient is counter, draw the ratio of n D/Sp (n) and D/Sa (n);
(5) ratio of comparison D/Sp (n) and D/Sa (n), find out the maximum of D/Sp (n) and D/Sa (n), the maximum of D/Sp (n) and D/Sa (n) is pairing, and exert pressure time Inf (N) and release pressure time D ef (N) promptly is best applying and the release pressure time; If the pairing asynchronism(-nization) of maximum of D/Sp (n) and D/Sa (n), then the pairing time of maximum with D/Sa (n) serves as preferred.
(6) use above-mentioned the best apply with the release pressure time can be by patient after the anti-treatment a period of time of fighting, is searched near this best time value again, so that obtain best more accurately applying and the release pressure time.Circulate with this, bring in constant renewal in best applying and the release pressure time.
(7) use the applying of the best of above-mentioned acquisition to can be used as counter next time initial the applying and the release pressure time of fighting and treating of same patient with the release pressure time.Anti-therapeutic effect the best of fighting like this.
The invention has the advantages that: owing to determine that by the maximum of searching D/Sp (n) and D/Sa (n) anti-the best of fighting of patient applies and the release pressure time value, compared with the prior art, be not only to determine the anti-function assessment index of fighting by single cardiovascular blood flow, optimum pressing time of the result who adopts that single cardiovascular blood flow determines to obtain is not accurate enough, and can not reflect the anti-effect of fighting of human body exactly; The present invention is simple and reliable; Can seek, follow the tracks of the best automatically when therefore, use is of the present invention in external counterpulsation apparatus applies and the release pressure time.
Description of drawings
The invention will be further described below in conjunction with the drawings and specific embodiments:
Fig. 1 is the method for 97112592 the anti-function assessment index of fighting of foundation for the application number of prior art;
Fig. 2-Fig. 3 is the variation diagram of human finger pulse (or temporo tremulous pulse or ear arteries and veins) signal in anti-preceding, counter the fighting of fighting;
Fig. 4 is the method for calculating DSa of the present invention and DSp;
Fig. 5-Fig. 7 is that human finger pulse (or temporo tremulous pulse or ear arteries and veins) signal is applied the sketch map with release pressure time variable effect (too early, best, too late) in the anti-process of fighting;
Fig. 8 seeks, follows the tracks of the best automatically and applies flow chart with the release pressure time
The specific embodiment
The present invention seeks automatically, follows the tracks of and adjusts external counterpulsation apparatus the best and apply and the release pressure time method, its use D/Sp and D/Sa ratio to seek automatically, follow the tracks of to adjust apply with the flow process of release pressure time as shown in Figure 8.Specifically it is achieved in that
Refer to that arteries and veins (or temporo tremulous pulse or ear arteries and veins) signal is exactly the blood-flow waveform of human finger position (or temporo tremulous pulse position or ear position),, this bio signal is converted to the signal of telecommunication by energy transducer; After processing such as amplification, filtering, A/D conversion, gather and preserve by CPU, wait for software processes.Human finger pulse (or temporo tremulous pulse or ear arteries and veins) signal variation such as Fig. 2, shown in Figure 3 in anti-preceding, counter the fighting of fighting; Shown in the figure for before counter the fighting in the one-period and in the anti-process of fighting finger arteries and veins (or temporo tremulous pulse or ear arteries and veins) signal; As can be seen, the variation characteristic of the finger arteries and veins signal before counter fighting (or temporo tremulous pulse or ear arteries and veins) is not obvious, and very obvious at the variation characteristic of the anti-process middle finger arteries and veins signal (or temporo tremulous pulse or ear arteries and veins) of fighting.Among the figure, the S point is for shrinking crest, and D is the diastole crest, and B is flex point (the B point left side is a systole, and the right is a relaxing period).As seen in counter the fighting, the D point raises, and pairing relaxing period blood flow (area) also increases.
If P (t) is finger arteries and veins (or temporo tremulous pulse or the ear arteries and veins) signal after the acquisition process, T DBe diastolic wave
D / Sp = P ( T D ) P ( T S )
D / Sa = ∫ T b T c P ( t ) dt ∫ T a T b P ( t ) dt
The time of peak value (D point), T sBe the time of contraction wave peak value (S point), Ta is the time of contraction wave valley (A point), and Tb is the time of flex point between contraction wave and the diastolic wave (B point), and Tc is the time of contraction wave valley (C point), as shown in Figure 3.Represent the peakedness ratio of diastolic wave and contraction wave with D/Sp, and D/Sa represents the area ratio of diastolic wave and contraction wave, the method for calculating D/Sp and D/Sa so is as follows:
Beginning counter when treatment of fighting to the new patient, in the scope during this period of time before at first after the diastole particular safety time of generally acknowledging, arriving the paradoxical expansion particular safety time, set one and exert pressure time and release pressure time, be defined as Inf (0) and Def (0) respectively; Fight to patient is counter then, collection refers to arteries and veins (or temporo tremulous pulse or ear arteries and veins) signal, obtains contraction wave peak value (S point) and diastolic wave peak value (D point), calculates the ratio of D/Sp (0) and D/Sa (0) respectively according to the computing formula of D/Sp and D/Sa.
According to the variation of electrocardiosignal, determine to adjust the interval of exert pressure time and release pressure time, be defined as T1; After interval T1 arrived, the adjustment time of exerting pressure was Inf (1) and release pressure time to be that Def (1) fights to patient is counter, draws the ratio of another D/Sp (1) and D/Sa (1); After latency period T1 arrives, repeat this operation, adjust apply with the release pressure time for filling evacuation time Inf (n) and Def (n) fights to patient is counter, draw the ratio of n D/Sp (n) and D/Sa (n).
At the D/Sp (0) that calculates gained, D/Sp (1) ... D/Sp (n) and D/Sa (0), D/Sa (1) ... in D/Sa (n) sequence of ratio values, find out the maximum of D/Sp (n) and D/Sa (n), the maximum of D/Sp (n) and D/Sa (n) is pairing, and exert pressure time Inf (N) and release pressure time D ef (N) promptly is best applying and the release pressure time, and wherein N is between 0 to n.
If the pairing asynchronism(-nization) of maximum of D/Sp (n) and D/Sa (n), then the pairing time of maximum with D/Sa (n) serves as preferred.
What record was best applies and the release pressure time, go up patient after the anti-treatment a period of time of fighting between at this moment, again this best apply and the release pressure time value near search so that obtain best more accurately applying and the release pressure time.
After each treatment finishes, all applying with the release pressure time of this anti-the best of fighting preserved, can be used as initial the applying and the release pressure time of the counter next time treatment of fighting of same patient.
By test as can be known, in the anti-process of fighting, apply with the variation of release pressure time to the influence that refers to arteries and veins (or temporo tremulous pulse or ear arteries and veins) signal and change very greatly, Fig. 5-Fig. 7 represented the time of exerting pressure too early, best and situation too late.

Claims (3)

1, a kind ofly adjust the external counterpulsation unit optimum pressure from motion tracking and apply method with release time, its method step is as follows:
At first at the diastole of generally acknowledging, particular safety in paradoxical expansion particular safety time scope during this period of time in the past, is set exert pressure a time Inf (0) and a release pressure time D ef (0) after the time; Fight to patient is counter according to the Inf (0) and the Def (0) that set, collection refers to arteries and veins (or temporo tremulous pulse or ear arteries and veins) signal, calculate contraction wave peak value S point and diastolic wave peak value D point, calculate the ratio of D/Sp (0), the flex point that forwards the diastole crest with the contraction crest to is a separation, draw contraction wave peak area and diastolic wave peak area, calculate the ratio of D/Sa (0); ) be Inf (1) and release pressure time to be that Def (1) fights to patient is counter by the interval adjustment time of setting of exerting pressure, draw the ratio of another D/Sp (1) and D/Sa (1); Constantly adjust to apply and fight, draw the ratio of n D/Sp (n) and D/Sa (n) patient is counter with release pressure time Inf (n) and Def (n); The ratio that compares D/Sp (n) and D/Sa (n), find out the maximum of D/Sp (n) and D/Sa (n), the maximum of D/Sp (n) and D/Sa (n) is pairing, and exert pressure time Inf (N) and release pressure time D ef (N) promptly is best applying and the release pressure time; If the pairing asynchronism(-nization) of maximum of D/Sp (n) and D/Sa (n), then the pairing time of maximum with D/Sa (n) serves as preferred.This best apply with the release pressure time can be by anti-treatment a period of time of fighting to patient after, again this best apply and the release pressure time value near search so that obtain best more accurately applying and the release pressure time.
2, according to claim 1ly adjust the external counterpulsation unit optimum pressure from motion tracking and apply method with release time, it is characterized in that: the time of described the best can be used for the anti-treatment of fighting to patient, after a period of time, again this best apply and the release pressure time value near search, to obtain best more accurately applying and the release pressure time.
3, according to claim 1 and 2ly adjust the external counterpulsation unit optimum pressure from motion tracking and apply method with release time, it is characterized in that: apply and the release pressure time of the best of acquisition can be used as initial the applying and the release pressure time of the counter next time treatment of fighting of same patient.
CN 200510033145 2005-02-06 2005-02-06 Method for optimum pressure application and release time for automatic tracking and regulating external counter pulsation device Pending CN1647789A (en)

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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102106778A (en) * 2009-12-29 2011-06-29 深圳先进技术研究院 External counterpulsation controlling system and external counterpulsation controlling method
CN102499873A (en) * 2011-10-24 2012-06-20 重庆普施康科技发展有限公司 Automatic adjusting method of gas charging/ discharging time of external counter pulsation device
CN113288751A (en) * 2021-05-24 2021-08-24 中山大学附属第一医院 Portable device for improving vascular endothelial function

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102106778A (en) * 2009-12-29 2011-06-29 深圳先进技术研究院 External counterpulsation controlling system and external counterpulsation controlling method
CN102106778B (en) * 2009-12-29 2015-01-07 深圳先进技术研究院 External counterpulsation controlling system and external counterpulsation controlling method
CN102499873A (en) * 2011-10-24 2012-06-20 重庆普施康科技发展有限公司 Automatic adjusting method of gas charging/ discharging time of external counter pulsation device
CN102499873B (en) * 2011-10-24 2013-09-18 重庆普施康科技发展有限公司 Automatic adjusting method of gas charging/ discharging time of external counter pulsation device
CN113288751A (en) * 2021-05-24 2021-08-24 中山大学附属第一医院 Portable device for improving vascular endothelial function
WO2022247695A1 (en) * 2021-05-24 2022-12-01 中山大学附属第一医院 Portable apparatus for improving vascular endothelial function

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