CN1615165A - Applicator for facilitating delivery of a solution to a surface - Google Patents

Applicator for facilitating delivery of a solution to a surface Download PDF

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Publication number
CN1615165A
CN1615165A CNA028271343A CN02827134A CN1615165A CN 1615165 A CN1615165 A CN 1615165A CN A028271343 A CNA028271343 A CN A028271343A CN 02827134 A CN02827134 A CN 02827134A CN 1615165 A CN1615165 A CN 1615165A
Authority
CN
China
Prior art keywords
housing
container
solution
lid
conveyer device
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CNA028271343A
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Chinese (zh)
Inventor
米歇尔·许亚姆斯
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Norwood Abbey Ltd
Original Assignee
Norwood Abbey Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Norwood Abbey Ltd filed Critical Norwood Abbey Ltd
Publication of CN1615165A publication Critical patent/CN1615165A/en
Pending legal-status Critical Current

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M35/00Devices for applying media, e.g. remedies, on the human body
    • A61M35/003Portable hand-held applicators having means for dispensing or spreading integral media
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/18Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves
    • A61B18/20Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves using laser
    • A61B18/203Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves using laser applying laser energy to the outside of the body
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B2017/00743Type of operation; Specification of treatment sites
    • A61B2017/00747Dermatology
    • A61B2017/00765Decreasing the barrier function of skin tissue by radiated energy, e.g. using ultrasound, using laser for skin perforation
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00315Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body for treatment of particular body parts
    • A61B2018/00452Skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M2037/0007Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin having means for enhancing the permeation of substances through the epidermis, e.g. using suction or depression, electric or magnetic fields, sound waves or chemical agents

Abstract

A delivery device (10) for facilitating delivery of a solution to a surface, the device including: a receptacle (11, 12) for storage of the solution prior to delivery to the surface, the receptacle being operable between a closed orientation and an open orientation; an abutting face (21) which in use sealingly abuts the surface, the abutting face including an aperture which facilitates delivery of the solution to the surface and which is in fluid communication with the receptacle (11, 12) when the receptacle is in the open orientation; wherein as the receptacle is translated from the closed orientation to the open orientation the solution is released from the receptacle to the aperture of the abutting face while the abutting face (21) is maintained in sealing abutment with the surface.

Description

Make solution be easy to be transported to the applicator on surface
The present invention relates to a kind of applicator that makes solution be easy to be transported to the surface.Particularly, the present invention relates to a kind of making such as containing the applicator that the such treatment solution of solution medicine is easy to be transported to human or animal's skin.
Though applicator according to the present invention has multiple different application, for ease of reference, this paper will be limited to main application fields basically, promptly treat the conveying of solution.
Known have many systems that are used for medicine and vaccine delivery, wherein modal comprising by injection and oral induction system.And known other system comprises the system that is transported to skin by adhesive plaster and ointment.
The present invention provides a kind of applicator and induction system that makes treatment solution or drug conveying arrive skin easily.More specifically, the present invention provides a kind of easily and can be used to be connected with ablative device and will treat solution or the drug conveying applicator to skin.
According to an aspect of the present invention, provide a kind of applicator that makes solution be easy to be transported to the surface, this applicator comprises:
Container is used for stock solution before solution is transported to the surface, and this container can operate cutting out between orientation and the open orientation;
Binding face, it is fitted with face seal in use, this binding face comprises opening, this opening makes solution be easy to be transported to the surface, and when container is in open orientation and container be in the fluid connected state;
Wherein, when container forwarded open orientation to from cutting out the orientation, solution was released to the opening of binding face from container, and binding face keeps sealing to fit with the surface simultaneously.
Container is used for stock solution before course of conveying takes place, and it can take the form of any appropriate, as long as container can forward open orientation to from cutting out the orientation, makes that solution is easy to be transported to opening from container, so that solution can contact with the surface.In main application fields, promptly treat the conveying of solution, in drug conveying, the surface is patient's a skin.
In one embodiment, container comprise housing with at least one open partition and can with the threaded cap of housing threads engage, this lid comprises complementary partition, and when container is in when cutting out the orientation, complementary partition engages with the dividing plate of housing, so that solution is stored between the dividing plate, and its middle cover can rotate, to separate the dividing plate of housing and lid, make described container forward open orientation to, thereby make solution be discharged into the opening of binding face.
Housing can comprise the dividing plate of arbitrary number, and when each dividing plate engaged with the complementary partition of lid, it had constituted the subspace of container.Yet in a preferred embodiment, housing comprises four open partition, and it is in when closing the orientation at container and engages with four complementary partition of lid.
In another embodiment, container comprises housing with at least one open partition and the lid that engages with housing, this lid comprises complementary partition, it is in when closing the orientation at container and engages with the dividing plate of housing, so that solution is stored in the container, and wherein this lid comprises starting drive, to separate the dividing plate of housing and lid, and the lid make container forward open orientation to, thereby solution is discharged into the opening of binding face.
In this embodiment, preferably, at least one open partition of housing comprises the lug of pair of opposing, extend towards the center of housing its corresponding side from housing, and the dividing plate of lid comprises central tab, it engages with the lug of housing, and has constituted a gate (gate) between the lug of housing.
Preferably, the central tab of lid engages with starting drive, so that when starting drive starts, central tab is separated with the lug of housing, makes solution be discharged into the opening of housing.
Lid and housing can any appropriate form be fitted to each other.In one embodiment, cover to global facility and be installed on the housing, preferably, it is installed by manner.In another embodiment, lid comprises body part and the inserts part that is connected with hinging manner with the housing of container, it comprises central tab, and the housing of the top of tegmentum and container is clipped in the middle, and inserts partly comprises button, and it engages with central tab and has constituted starting drive.
According to noted earlier, can expect that the main application fields of applicator will be the conveying that comprises the therapeutic agent and the medicine of solution, the especially conveying of this class solution and the use that is connected of ablative device.
Known skin is carried out laser ablation to promote the conveying of medicine in skin.This process comprises laser beam is applied to skin surface, and the easier solution that comprises medicine that will be carried in surface is permeated.This technology is in depth considered in many patent documentations, will not refer in detail to here, only points out that ablative device generally includes transmitting terminal, and it has constituted the tip (tip) of device, and laser is launched by transmitting terminal.
In view of foregoing, and consider the main application fields that applicator is connected with ablative device, preferably, applicator is fit to engage with the tip of ablative device, and comprises forms, and ablating device can be by this forms emission laser.
The forms of applicator, the additional window that perhaps is arranged in the applicator can be so that observe the ablation locations of patient skin.In an embodiment that will relate in the back, applicator be attached to skin surface earlier before ablative device engages.In this case, the forms of container are convenient to by container skin be observed, to guarantee applicator is attached to the required position of skin surface.In this case, melt supposition with processed skin area because the location of applicator and by automatic aiming, after using ablative device, it is just unimportant whether can to observe skin by container so.
Although foregoing is arranged, in a preferred embodiment, forms are installed to cover and the corresponding position of the opening of applicator housing, so that the opening of forms that can be by lid when laser is launched and housing arrives patient's skin.
No matter be which kind of application, applicator all comprises binding face, and it will be transferred the face seal applying of arrival in use with solution.Preferably, binding face is positioned at the bottom surface of applicator housing, and preferably, is provided with a tack coat, when removing the protection sheet that covers on this tack coat, it can be attached on the surface.
Below with reference to accompanying drawings, for a more detailed description to embodiments of the invention, wherein:
Fig. 1 shows first embodiment of applicator;
Fig. 2 shows second embodiment of applicator; And
Fig. 3 shows first embodiment of the above-mentioned applicator that is connected with ablative device (LAD).
Fig. 1 shows an embodiment of applicator 10, and it is used to be connected with ablative device.In this respect, applicator 10 is equivalent to the connected tip of ablative device.
Applicator 10 comprises housing 11 and lid 12.Lid 12 is installed on the housing 11 by 13 screw threads of the screw thread on the housing 11.Housing 11 and lid 12 have constituted the container of stock solution before delivered solution arrives required surface.
Housing 11 comprises four dividing plates 14 around its circumference setting.Dividing plate 14 defines confined space 15 with the outer wall 16 of housing 11.Inwall 17 quilts of each dividing plate 14 are around on the opening 18 that is arranged on housing 11.
Lid 12 comprises four complementary partition (not shown), and each complementary partition engages with the inwall 17 of the respective diaphragms 14 of housing 11.When the complementary partition of lid 12 engaged with the dividing plate 14 of housing 11, the confined space 15 that is limited by dividing plate 14 was closed.Before solution is transported to required surface, solution is stored in this confined space.
Lid 12 can forward open orientation to from closing the orientation according to the direction of arrow that lid illustrates on 12, covers 12 complementary partition thus and separates with the inwall 17 of the respective diaphragms 14 of housing 11.This make in the confined space 15 the solution of adorning be discharged into opening 18 by the slit 19 between the inwall 17 of dividing plate 14 easily.
During use,, applicator 10 is attached on the surface, on the people's especially to be administered skin by removing protection sheet 20 from applicator 10 to expose the adhesive tape 21 on the bottom surface that is positioned at housing 11.In case applicator 10 is fixed to skin surface, just ablative device can be engaged with the lid 12 of applicator 10, guarantee to engage by the double pointed nail 22 that matches with ablative device.
After applicator 10 engaged, ablative device was by covering the opening 23 emission laser in 12, and opening 23 is embedded with lens 24.Then, arrive skins by covering the opening 18 that laser that 12 opening 23 penetrates passes lens 24 and housing 11.Therefore, promote the melting of skin below the applicator 10, especially the skin of open area melts.
In case reach needed amount of ablation, the Laser emission of ablative device promptly stops.Then, rotatable cover 12 is to discharge the solution that comprises required medicine from the confined space 15 of housing 11.This solution is discharged into opening 18 places, is melted skin surface with quilt simultaneously and contacts.
Applicator 10 can be fixed on needed position by bonding strip 21, and long enough so that solution is melted the skin surface infiltration by quilt.
With reference to Fig. 2, also provide a kind of applicator 30 that comprises housing 31 and lid 32.Covering 32 in this embodiment is connected with housing 31 in hinged way by hinge 33.
Housing 31 comprises a plurality of dividing plates 34, and its outer wall 36 with housing 31 defines confined space 35.Confined space 35 had and will be transported to the solution of skin surface before using applicator 30.
In this embodiment, applicator 30 is equipped with inserts 37, and it is clipped in the middle by housing 31 and lid 32.Inserts 37 also can be one-body molded with lid 32.Inserts 37 comprises lug 38, and it is by in the slit 39 that slides into dividing plate 34 and engage with the dividing plate 34 of housing 31.Lug 38 engages by the button 40 of inserts 37, and when lid 32 engaged with housing 31, button 40 is protrusion from cover 32 opening 41.
During use,, remove protection sheet 42 to expose the adhesive layer 43 on the bottom surface that is positioned at housing 31 according to this embodiment.Then, applicator 30 is placed into skin area and fixing by adhesive layer 43.At this moment, lid 32 engages with housing 31, and button 40 is protrusion from cover 32 opening 41, and the lug 38 of inserts 37 engages with the dividing plate 34 of housing 31.
In case applicator 30 is fixed on the skin, ablative device just engages with lid 32, and emission laser.Laser is by covering 32 opening 44, and opening 44 is embedded with lens 45.Opening 44 and lens 45 are set directly at the top of the opening 46 of housing 31.Like this, the ablative device emitted laser can be passed and be covered 32 the opening 44 and the opening 46 of housing 31, to melt the skin below the opening 46.
In case reach needed degree of ablation, the Laser emission of ablative device promptly stops.After this, make lug 38 separate with the dividing plate 34 of housing 31 by pressing button 40, the solution of being adorned in the confined space 35 of housing 31 is released to opening 46.
Applicator 30 keeps staying the sufficiently long time on the skin, makes solution go deep into skin.This time can be detected by the chemical compound of change color, and the form that this chemical compound can be arranged on the tablet 47 in the housing 31 occurs.
With reference to Fig. 3, applicator 10 can be connected on the ablative device 50 at an easy rate for use.Can adopt the method for above-described any appropriate to realize this connection.
In this description and following claims, unless context has requirement in addition, word " comprise " and be understood to include described individuality or step such as " comprises " and variations such as " comprising ", or one group of described individuality or step, get rid of other individuality or step or individuality in groups or step arbitrarily and should not be construed as.
This explanation is not quoting of any prior art, should not be taken as approval yet or hint that those prior arts have constituted the part of Australian common practise.
One of ordinary skill in the art will appreciate that the present invention described herein is easy to change and revises and be inequality with those specific descriptions.Be appreciated that and the present invention includes all these change that meets spirit and scope of the invention and modifications.The present invention also comprises step, feature, compositions and the chemical compound that all are mentioned separately or jointly or point out in this manual, and any and all combinations of any two or more described steps or feature.

Claims (13)

1. one kind makes solution be easy to be transported to surperficial conveyer device, and described device comprises:
Container was used for before described solution is transported to described surface storing described solution, and described container can operate cutting out between orientation and the open orientation;
Binding face, it is fitted with described face seal in use, described binding face comprises opening, described opening makes described solution be easy to be transported to described surface, and when described container is in described open orientation and described container be in the fluid connected state;
Wherein, when described container from described when closing the orientation and forwarding described open orientation to, described solution is released to the opening of described binding face from described container, described binding face keeps the sealing applying with described surface simultaneously.
2. conveyer device according to claim 1, wherein, described container comprise housing with at least one open partition and can with the threaded cap of described housing threads engage, described lid comprises complementary partition, when described container is in described when cutting out the orientation, described complementary partition engages with the dividing plate of described housing, so that described solution is stored between the described dividing plate, and wherein said lid can rotate, to separate the dividing plate of described housing and described lid, make described container forward described open orientation to, thereby make described solution be discharged into the opening of described binding face.
3. conveyer device according to claim 2, wherein, described housing comprises four open partition, when described container is in describedly when cutting out the orientation, it is engaged with four complementary partition of described lid.
4. conveyer device according to claim 1, wherein, described container comprises housing with at least one open partition and the lid that engages with described housing, described lid comprises complementary partition, when described container is in when cutting out the orientation, it is engaged with the dividing plate of described housing, so that described solution is stored in the described container, and wherein said lid comprises starting drive, to separate the dividing plate of described housing and described lid, make described container forward described open orientation to, thereby described solution is discharged into the opening of described binding face.
5. conveyer device according to claim 4, wherein, the open partition of described at least one housing comprises the lug of pair of opposing, extend towards the center of described housing its corresponding side from described housing, and the dividing plate of described lid comprises central tab, it engages with the lug of described housing, and has constituted gate between the lug of described housing.
6. conveyer device according to claim 5, wherein, the central tab of described lid engages with described starting drive, so that when described starting drive starts, described central tab is separated with the lug of described housing, so that described solution is discharged into the opening of described housing.
7. conveyer device according to claim 6, wherein, described lid is that global facility is installed on the described housing, preferably installs by manner.
8. conveyer device according to claim 6, wherein, described lid comprises the body part that is connected with hinging manner with the housing of described container, with the inserts part, it comprises described central tab, and be clipped in the middle by the housing of the top of described lid and described container, described inserts partly comprises button, it engages with described central tab and has constituted described starting drive.
9. conveyer device according to claim 1, wherein, described conveyer device is a delivery device, the solution that is used for comprising medicine is transported to patient's skin.
10. conveyer device according to claim 9, wherein, described conveyer device is suitable for being connected with ablative device use.
11. conveyer device according to claim 10, wherein, described conveyer device is suitable for engaging with the tip of described ablative device, and comprises forms, can observe patient's skin by described forms, and described ablating device can be by described forms emission laser.
12. conveyer device according to claim 11, wherein, described forms are positioned at described covering and the corresponding position of the opening of described container casing, so that make the opening of forms that emitted laser can be by described lid and described housing arrive patient's skin.
13. conveyer device according to claim 1, wherein, described binding face is positioned at the bottom surface of described container casing, and preferably is provided with tack coat, when removing the protection sheet that covers on the described tack coat, it can be attached on the described surface.
CNA028271343A 2001-12-05 2002-12-05 Applicator for facilitating delivery of a solution to a surface Pending CN1615165A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
AUPR9323 2001-12-05
AUPR932301 2001-12-05

Publications (1)

Publication Number Publication Date
CN1615165A true CN1615165A (en) 2005-05-11

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Application Number Title Priority Date Filing Date
CNA028271343A Pending CN1615165A (en) 2001-12-05 2002-12-05 Applicator for facilitating delivery of a solution to a surface

Country Status (4)

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EP (1) EP1461114A4 (en)
CN (1) CN1615165A (en)
CA (1) CA2473206A1 (en)
WO (1) WO2003047680A1 (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106267435A (en) * 2015-06-26 2017-01-04 佘钊炜 A kind of transfusion accessory detecting transfusion liquid parameter and the method for detection transfusion liquid parameter
CN106310425A (en) * 2015-07-31 2017-01-11 佘钊炜 Infusion accessory capable of detecting pH value of infusion fluid and method for detecting pH value of infusion fluid

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB191212593A (en) * 1912-05-28 1913-07-28 Ignatius Knaster Improvements in and relating to the Application of Liquids, Semi-liquids and the like.
US4460370A (en) * 1981-10-29 1984-07-17 Almedco, Inc. Trans-dermal medication application cell
US5643252A (en) * 1992-10-28 1997-07-01 Venisect, Inc. Laser perforator
US5462743A (en) * 1992-10-30 1995-10-31 Medipro Sciences Limited Substance transfer system for topical application
US6251100B1 (en) * 1993-09-24 2001-06-26 Transmedica International, Inc. Laser assisted topical anesthetic permeation

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106267435A (en) * 2015-06-26 2017-01-04 佘钊炜 A kind of transfusion accessory detecting transfusion liquid parameter and the method for detection transfusion liquid parameter
US10842715B2 (en) 2015-06-26 2020-11-24 Zhaowei She Infusion accessory capable of detecting infusion liquid parameters and method of detecting infusion liquid parameters
CN106310425A (en) * 2015-07-31 2017-01-11 佘钊炜 Infusion accessory capable of detecting pH value of infusion fluid and method for detecting pH value of infusion fluid

Also Published As

Publication number Publication date
EP1461114A4 (en) 2006-04-26
WO2003047680A1 (en) 2003-06-12
EP1461114A1 (en) 2004-09-29
CA2473206A1 (en) 2003-06-12

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