CN1593687A - Microwave coagulation therapeutic apparatus for inter-tissue tumor - Google Patents

Microwave coagulation therapeutic apparatus for inter-tissue tumor Download PDF

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Publication number
CN1593687A
CN1593687A CN 200410041140 CN200410041140A CN1593687A CN 1593687 A CN1593687 A CN 1593687A CN 200410041140 CN200410041140 CN 200410041140 CN 200410041140 A CN200410041140 A CN 200410041140A CN 1593687 A CN1593687 A CN 1593687A
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CN
China
Prior art keywords
microwave
needle
tumor
treatment instrument
solidification treatment
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Pending
Application number
CN 200410041140
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Chinese (zh)
Inventor
张鹏
张庆海
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NANJING QINGHAI MICROWAVE ELECTRONIC RESEARCH INSTITUTE
NANJING QIYA MEDICAL EQUIPMENT CO Ltd
Original Assignee
NANJING QINGHAI MICROWAVE ELECTRONIC RESEARCH INSTITUTE
NANJING QIYA MEDICAL EQUIPMENT CO Ltd
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Application filed by NANJING QINGHAI MICROWAVE ELECTRONIC RESEARCH INSTITUTE, NANJING QIYA MEDICAL EQUIPMENT CO Ltd filed Critical NANJING QINGHAI MICROWAVE ELECTRONIC RESEARCH INSTITUTE
Priority to CN 200410041140 priority Critical patent/CN1593687A/en
Publication of CN1593687A publication Critical patent/CN1593687A/en
Pending legal-status Critical Current

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  • Radiation-Therapy Devices (AREA)

Abstract

The invention discloses a microwave coagulation therapeutic apparatus for inter-tissue tumor, which comprises a microwave launching apparatus, a temperature measuring and controlling arrangement, a puncturing needle and a microwave antenna, wherein insulators are arranged between the piercing head of the puncturing needle and the needle tube, the needle tube is provided with a microwave antenna leading from the microwave launching apparatus and extending to the insulators.

Description

Tumor microwave solidification treatment instrument between tissue
Technical field
The present invention relates to a kind of tumor-treatment instrument, especially a kind of instrument that adopts the micro-wave therapeutic tumor belongs to the armarium technical field.
Background technology
Microwave puncture solidification treatment (puncture microwave cogulation therapy is called for short PMCT) cancerous protuberance is a special kind of skill that nearly ten years fork-like farm tools used in ancient China have developed fork-like farm tool used in ancient China.
It is reported that existing microwave tumor coagulating treatment instrument mainly is made up of microwave transmission system, puncture needle, microwave antenna, temperature measuring and control device.With treatment hepatocarcinoma is example, its process is by the guiding of Ultrasound Instrument and accurately locatees, the puncture needle percutaneous is presented to the inside of liver tumor, again the microwave antenna of shank shape is delivered to inside tumor by the endoporus of puncture needle, the part of antenna launched microwave is stretched out the puncture needle endoporus.After this add microwave, the microwave direct heating tumor tissues from the antenna emission makes its intensification.When temperature surpassed 60 ℃, tumor tissues will coagulation necrosis.Along with the prolongation that adds the microwave time, the zone of coagulation necrosis progressively enlarges in the tumor, becomes the punching bag shape.This method claims microwave ablation again, because easy, the Wicresoft, painless of operation process, survival rates can match in excellence or beauty with excision again, so developed rapidly in Japan, the U.S. and China.
Relevant situation can referring to:
1.Toshihito?SK,Masayuki?W,Taiichi?N,et?al。Percutaneous?Microwave?Coagulation?Therapy?forPatients?with?Small?Hepatoxwllular?Caecinoma,Cancer,1999,85,1694-1720;
2. money Songxi, Xie Qiliang, Zhao Jinxin, the transurethral microwave irradiation adds TURP treatment hyperplasia of prostate, Chinese magazine of urology surgery, 1990,11:235;
3. Chen Yi, Zhao Jinxin, it is good etc. to thank to enterprise, microwave per urethra temperature control micro-wave therapeutic hyperplasia of prostate, Chinese physical therapy magazine, 1994,17:84;
4. Chen Yi, Xie Qiliang, the clinical practice of plug-in type microwave antenna, Chinese physical therapy magazine, 1990,13:133, Zhou Xiaoping, applied microwave adds the clinical observation of the temperature therapy excision cerebral tumor, Chinese physical therapy magazine, 1991,14:50 in the art;
5. Chen Yi, Xie Qiliang, microwave irradiation therapy metrorrhagia, Chinese physical therapy magazine, 1991,14:40, Chen Yi, Xie Qiliang, Feng Aiyu, solidification treatment internal hemorrhoid 42 examples in the microwave hemorrhoid, Chinese physical therapy magazine, 1995,18:9;
6. Li Ping liter, hematoporphyrin derivative microwave be through branchofiberoscope internal-radiation therapy lung bronchogenic carcinoma, Chinese tuberculosis and respiratory illness magazine, 1986,9:98;
The patent inventor of inventor herein Ceng Zuowei microwave solidification treatment instrument (patent No. 892050950 letters patent book numbers 53696) has also carried out secular effort at the treatment liver cancer, and this development of technology has been played impetus.
Yet existing microwave puncture coagulating treatment instrument all has the following disadvantages or problem: 1, puncture needle and microwave antenna are separated from one another, and inconvenience is arranged during use more; 2, the shank intensification is hot, scalds stomach wall and normal tissue easily; 3, owing to there is microwave interference, therefore be difficult to measure the instantaneous temperature of tissue.
Summary of the invention
Primary and foremost purpose of the present invention is: deficiency or problem at above prior art exists, tumor microwave solidification treatment instrument between a kind of tissue is proposed, and this instrument can organically combine puncture needle and microwave antenna, thereby brings more convenience to use.
Further aim of the present invention is: propose a kind ofly scientifically to solve the shank tumor microwave solidification treatment instrument between the tissue of hot problem that heats up, thereby avoid scalding stomach wall and normal tissue.
Further object of the present invention is: propose a kind of can be to carrying out tumor microwave solidification treatment instrument between accurate thermometric tissue in the microwave field, thereby be achieved the heat temperature control of process of tumor on this basis.
In order to reach above primary and foremost purpose, tumor microwave solidification treatment instrument comprises microwave launcher, temperature measuring and control device between tissue of the present invention, and puncture needle and microwave antenna.Wherein, described puncture needle and microwave antenna are integrated, and formation can puncture and microwave needle that can launched microwave.Be fixed with insulator between the puncturing head of described puncture needle and the needle tubing, be equipped with in the described needle tubing and draw from microwave launcher and extend to the microwave antenna of insulator.
In order to reach above further purpose, be provided with the fluid injection and the liquid return hole of external circulating pump in the ring cavity between above-mentioned needle tubing and microwave antenna.
In order to reach above further purpose, hygrosensor spare is installed between above-mentioned puncturing head and insulator, the signal output part of this device is measured and control device by the holding wire external temperature that is arranged in the needle tubing.
Obviously, the present invention is an one with puncture needle and microwave antenna organic assembling dexterously, it can be punctured and can launched microwave, becomes what is called " microwave needle ".As a result, dwindle the puncture external diameter, alleviated patient's pain, and firm in structure, not only easy to operate, can also make the accurate positioning of antenna.Secondly, ring cavity can adopt recirculated water cooling easily in the needle tubing of the present invention, has therefore effectively avoided the interior normal structure of needle track to be scalded.In addition, the hygrosensor spare that the present invention is provided with microwave isolated and with the tumor tissues thermally coupled, therefore can not be subjected to microwave interference accurately to measure the instantaneous temperature of tumor tissues this point, lay a good foundation thereby control for precise dose.
This shows that the present invention compared with prior art has outstanding substantive distinguishing features and obvious improvement.
Description of drawings
The present invention is further illustrated below in conjunction with accompanying drawing.
Fig. 1 is the overall structure sketch map of one embodiment of the invention.
Fig. 2 is the external structure sketch map of microwave needle among Fig. 1 embodiment.
Fig. 3 is the internal structure sketch map of microwave needle among Fig. 1 embodiment.
The specific embodiment
Embodiment one
Tumor microwave solidification treatment instrument is settled microwave launcher, temperature measuring and control device as shown in Figure 1 between the tissue of present embodiment in the main frame, settles circulating pump on the main frame.
The structure of microwave needle is fixed with insulator 5 between puncturing head 4 and the needle tubing 3 as shown in Figures 2 and 3, and the microwave antenna 7 that links to each other, extends to insulator 5 with microwave launcher is equipped with at needle tubing 3 centers.In the ring cavity between needle tubing 3 and the microwave antenna, be provided with thin footpath liquid injection pipe 2 and liquid back pipe 1 that outer loop pump import and export respectively links to each other, the mouth of pipe of liquid injection pipe 2 is positioned near needle tubing 3 front ends, the mouth of pipe of liquid back pipe 1 is positioned near needle tubing 3 rear ends, so more helps the abundant circulation of cooling water.The temperature measuring head 8 of mounting strap shielding between puncturing head 4 and insulator 5, the signal output part of this temperature measuring head is by being arranged on temperature measuring and the control device in the holding wire 6 external main frames in the needle tubing 3.
Needle handle 9 one sides that needle tubing 3 rear ends are connected are shaped on the inlet opening and the liquid outlet of hypsokinesis, and opposite side is shaped on the temperature signal line fairlead of hypsokinesis, and the rear end is the microwave antenna fairlead.
Be not difficult to find out that the present invention at first is integrated the function of puncture needle and microwave antenna, can puncture and can launched microwave that its superior part has:
1, dwindled the puncture external diameter.For example, the external diameter of existing puncture needle G14 is 2.2mm, and microwaves corresponding pin external diameter has only 1.7mm, can alleviate patient's injury and pain like this.
2, in the traditional method, the syringe needle of puncture needle is hollow, and when microwave antenna passed endoporus, owing to stopping of tumor tissues, the bending distortion maybe needed the puncture needle withdraw of the needle easily.And the puncture head end of microwave needle is sharp, and is firm in structure, not only makes operation become convenient, also helps the accurate location of antenna.
3, solved simultaneously that microwave antenna end in the traditional method is soft, the problem of structural strength difference.
Secondly, in the process of tumors such as the hepatocarcinoma of PMCT treatment in the past, shank is hot to be a great problem.When adding microwave, the coaxial cable of Transmission Microwave in the microwave antenna is because thin loss is very big, and it is hot to cause the shank surface temperature to raise rapidly, scalds stomach wall and normal hepatic tissue easily, usually needs to cool off with ice bag or water bag, with the protection stomach wall.Hot for fear of shank, strengthen microwave power and prolongation and add the microwave time and be restricted, the area size that is solidified of tumor also is restricted as a result.Therefore document announcement is arranged, PMCT only is applicable to the tumor of straight warp≤5CM.Adopt the cooling system of above structure then can with the shank surface temperature control in 30 ℃, increase substantially the load of microwave cable, can improve microwave power and the time that adds microwave, avoided the interior normal structure of needle track to be scalded effectively.Owing to improved microwave power and added the microwave time, therefore strengthened the volume that is solidified in the tumor, experiment shows, but single needle original position deactivation diameter reaches the tumor of 7CM, has changed the notion that conventional P MCT can only the little tumor of deactivation.
In addition, during microwave coagulation, tumor tissues is among the powerful microwave electric field.If measure the instantaneous temperature of tissue this moment, no matter adopt the method for thermocouple or critesistor, all can can't work owing to microwave interference.How accurate thermometric in microwave field is a global difficult problem.The present invention has designed miniature band shielding temperature measuring head, and is isolated with microwave, but with the tumor tissues thermally coupled.This instantaneous temperature of tumor tissues is obtained by temperature measuring head immediately, and the small electric kinetic potential by temperature measuring head obtains also demonstrates fork-like farm tool used in ancient China through amplifying back input main frame, and temperature measurement accuracy can reach ± and 0.2 ℃, therefore realized the accurate thermometric in the microwave field.
Above accurate thermometry is combined with the microwave power control circuit, can realize the heat accurate temperature controller of process of tumor.
Clinical verification shows that tumor microwave solidification treatment instrument is easy to operate between the tissue of present embodiment, and patient's misery is little, the therapeutic effect ideal.

Claims (5)

1. tumor microwave solidification treatment instrument between a tissue, comprise microwave launcher, temperature measuring and control device, and puncture needle and microwave antenna, it is characterized in that: described puncture needle and microwave antenna are integrated, formation can puncture and microwave needle that can launched microwave, be fixed with insulator between the puncturing head of described microwave needle and the needle tubing, be equipped with in the described needle tubing and draw from microwave launcher and extend to the microwave antenna of insulator.
2. according to tumor microwave solidification treatment instrument between the described tissue of claim 1, it is characterized in that: the fluid injection and the liquid return hole that are provided with external circulating pump in the ring cavity between described needle tubing and the microwave antenna.
3. according to tumor microwave solidification treatment instrument between the described tissue of claim 2, it is characterized in that: hygrosensor spare is installed between described puncturing head and the insulator, and the signal output part of this device is measured and control device by the holding wire external temperature that is arranged in the needle tubing.
4. according to tumor microwave solidification treatment instrument between claim 2 or 3 described tissues, it is characterized in that: described liquid injection port is positioned near the needle tubing front end, and liquid return hole is positioned near the syringe rear end.
5. according to tumor microwave solidification treatment instrument between the described tissue of claim 4, it is characterized in that: needle handle one side that described syringe rear end is connected is shaped on the inlet opening and the liquid outlet of hypsokinesis, opposite side is shaped on the temperature signal line fairlead of hypsokinesis, and the rear end is the microwave antenna fairlead.
CN 200410041140 2004-07-01 2004-07-01 Microwave coagulation therapeutic apparatus for inter-tissue tumor Pending CN1593687A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN 200410041140 CN1593687A (en) 2004-07-01 2004-07-01 Microwave coagulation therapeutic apparatus for inter-tissue tumor

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Application Number Priority Date Filing Date Title
CN 200410041140 CN1593687A (en) 2004-07-01 2004-07-01 Microwave coagulation therapeutic apparatus for inter-tissue tumor

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CN1593687A true CN1593687A (en) 2005-03-16

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101541248B (en) * 2006-10-10 2013-05-29 克里奥医药有限公司 Needle structure and method of performing needle biopsies

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101541248B (en) * 2006-10-10 2013-05-29 克里奥医药有限公司 Needle structure and method of performing needle biopsies
CN103284764A (en) * 2006-10-10 2013-09-11 克里奥医药有限公司 Surgical device
CN103284764B (en) * 2006-10-10 2015-02-11 克里奥医药有限公司 Surgical device

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