CN1586696A - Desorb-heat extracting two-step extracting method for plant active component - Google Patents

Abstract

The two-step desorbing and heat extracting extraction process of effective plant component includes first desorbing the effective component from embedding or adsorbing plant tissue with small amount of water solution of alcohol and then extraction with hot solvent. Compared with available technology, the present invention has the advantages of short extraction time, low power consumption, 5-10 % raised yield, 5-30 % raised effective component content in the extracted matter and over 10 times lower solvent consumption compared with alcohol extraction process.

Description

Desorb-the Re of effective ingredients in plant puies forward two step extraction methods

Technical field

The present invention relates to the extracting method of effective ingredients in plant in the separation engineering, particularly effective ingredients in plant adopts desorb-Re to put forward the method for two steps extraction.

Background technology

Active ingredient in the plant is usually by plant tissue embedding and absorption, be provided with certain obstacle to extraction, conventional extracting method adopts a single solvent such as a step such as water, alcohol and benzinum to extract, this method only needs a kind of extraction solvent, simple to operation, extraction rate is slow, yield is low, CE impurity reaches shortcomings such as energy consumption is big more but exist.To some water-soluble extracts active ingredients preferably, often, also adopt alcohol extract, thereby increased the consumption of ethanol in order to improve the impurity content of yield and reduction CE.Some modern extracting methods are extracted as microwave and ultrasonic wave, and extraction rate reaches the yield height soon, but will realize industrialization, and production cost is still than higher.

Summary of the invention

The purpose of this invention is to provide a kind of extraction time short, yield is high, the product impurity content is low and the effective plant component extracting process of easy realization, it is characterized in that earlier extracting with hot solvent then with the small amount of ethanol aqueous solution active ingredient is desorbed from the plant tissue embedding and adsorbing.

Basic principle of the present invention is that the process that active ingredient is suggested the solvent from plant tissue inside is in two steps, the first step is active ingredient desorb from plant tissue embedding and absorption, the solvent that this step needs is called strippant, strippant has strong infiltration and destroy the ability of organization structure of the plant and the ability that active ingredient is cemented out from adsorbed state, for example certain density ethanol water, its infiltration and destruction organization structure of the plant and desorption ability are stronger, are a kind of strippants of nontoxic cheapness.Second step was that active ingredient is transferred to the outside from plant tissue inside, the solvent that this step needs is called the extraction solvent, the ratio of solvent strippant requires low, as long as can dissolve active ingredient, the higher solvent of temperature be dissolved with the strippant of active ingredient under the effect of temperature and concentration difference, the mutual rapid diffusion of portion within plant tissue, extraction rate is accelerated greatly.The temperature of desorption process is generally normal temperature, and the strippant consumption is also less, thereby the impurity level that desorption process produces seldom, and the speed of follow-up extraction is fast, and impurity proposition amount is few, and whole process extract impurity content lacks than one-step method.

Performing step of the present invention and condition are as follows:

(1) dried or half-dried plant are ground into granularity＞20 orders;

(2) add the ethanol water that concentration is 50%～85%, quantity is weight of material 60%～200% and make material evenly moistening, normal temperature was placed 5～60 minutes down;

(3) solvent extraction of adding more than 50 ℃ is one to three time, each 5～30 minutes.

The present invention compares with existing extractive technique, and its outstanding substantive distinguishing features and obvious improvement is:

(1) extraction time shortens 2～6 times, realizes easily.

(2) directly add hot solvent after the desorb, extractor can save heater, and the operation cycle is short, and energy consumption is low.

(3) yield improves 5%～10%, and the active constituent content of extract improves 5%～30%, and later separation and purification are more easy.

(4) to the leaching process of available water as solvent, the ethanol consumption reduces more than 10 times than alcohol extracting.

The specific embodiment

Embodiment one

The extraction of chlorogenic acid in the honeysuckle: dried honeysuckle powder is broken into 20～50 orders, adding weight of material 60%～140%, concentration are 60%～80% ethanol water, desorb is 5～20 minutes under the normal temperature, use twice of 85～100 ℃ of hot water extracting at last, each 10～15 minutes, to carry and comparing with an existing step water, extraction time reduces 3 times, the yield of chlorogenic acid increases by 8%, and chlorogenic acid contents improves 30% in the CE.

Embodiment two

The extraction of flavones in the ginkgo leaf: dry Folium Ginkgo is ground into 50～100 orders, it is fully wetting to add weight of material 80%～180%, concentration and be 50%～80% alcohol, desorb is 10～40 minutes under the normal temperature, use 70～80 ℃ at last, 30%～60% alcohol extract twice, each 10～20 minutes, compare with an existing step alcohol extracting, extraction time reduces 4 times, and the yield of flavones increases by 6%, and the content of flavones improves 15% in the CE.

Claims (2)

1, a kind of desorb-Re of effective ingredients in plant puies forward two step extracting methods, it is characterized in that earlier extracting with hot solvent then with the small amount of ethanol aqueous solution active ingredient is desorbed from the plant tissue embedding and adsorbing.

2,, it is characterized in that the extraction step of two-step method and condition are as follows according to the method shown in the claim 1:

(1) dried or half-dried plant are ground into granularity＞20 orders;

(2) add the ethanol water that concentration is 50%～85%, quantity is weight of material 60%～200% and make material evenly moistening, normal temperature was placed 5～60 minutes down;

(3) solvent extraction of adding more than 50 ℃ is one to three time, each 5～30 minutes.