CN1583019A - Anti-oxidation health care nutrient oil - Google Patents
Anti-oxidation health care nutrient oil Download PDFInfo
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- CN1583019A CN1583019A CN 200410022627 CN200410022627A CN1583019A CN 1583019 A CN1583019 A CN 1583019A CN 200410022627 CN200410022627 CN 200410022627 CN 200410022627 A CN200410022627 A CN 200410022627A CN 1583019 A CN1583019 A CN 1583019A
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- vitamin
- oil
- carotene
- sterol
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Abstract
An antioxidizing nutritive health-care oil is prepared from docosanol, beta-carotene, sterol, VE and corn germ oil.
Description
One, technical field
The present invention relates to a kind of wholefood and extract the preparation health nutritive oil, especially have the oxidation-resisting health-care nutritional oil.
Two, background technology
The developing history of China's health food is long, and the viewpoint of " integration of edible and medicinal herbs " and " Diet cures more than the doctors " is just arranged a long time ago.
Vitamin E is a kind of important free radical scavenger, and ultra-oxygen anion free radical, hydroxy radical, lipid peroxidation free radical and other free radicals and singlet oxygen are all had scavenging action.It has different physiological roles in addition: keep erythrocytic integrity, some material is synthetic in the control agent, participates in the DNA biosynthetic process, suppresses to contain selenium protein and iron content protein oxidation, and the protection sulfydryl is relevant with reproductive function.Research finds that also vitimin supplement E can improve 6SH-Px and SOD enzyme activity, improves energy metabolism of myocardial under the anoxia condition, is an important step that reduces the anoxia cardiac damage.Vitamin E disturbs peroxide enzyme chain reaction protection plasma membrane to be immune against attacks by blocking-up free radical level.Vitamin E can also reduce T-CHOL in the blood, content of triglyceride, the high density lipoprotein increasing cholesterol levels, and the protection persons vascular system improves health slow down aging.
Octacosanol is simple saturated straight chain aliphatic alcohol, is universally acknowledged resisting fatigue material, also has oxidation resistance.Doctor T.K.Cureton of Illinois, US university has at first found the reproductive disease that octacosanol can be treated cattle, and effective equally to human body.Therefore doctor Cureton also is cited as " father of International Health ".Octacosanol is still indeterminate to the functional mechanism of action of human body and other animal, but can be clear and definite be that octacosanol is absorbed in animal intestinal, and is that carrier passes intestinal wall with phospholipid and single, double glyceride mainly, enters blood.
Beta-carotene can change into vitamin A in human body, so also be called by people " provitamin A ".So carotene has the function of vitamin A, promptly have the health of keeping epithelial tissue, keep normal vision, promote growth and improve effects such as immunity.In addition, carotene also has the effect of unexistent better antioxidation of vitamin A and prevention canceration.Beta-carotene is avoided playing an important role in the damage of light, air and phytochrome at the protection cell, carotenoid can be directly and active oxygen react.
From with greasy relation, plant sterol is as a kind of functional components, by the characteristic of itself, is vitaminogenic character, can not synthesizing phytosterol in the human body, but human body is taken in plant sterol and can be hindered absorption to cholesterol; Plant sterol also has the antiinflammatory action of similar crovaril and hydrocortisone, and safe; Plant sterol has the blocking-up carcinogen and brings out the function that cancerous cell forms; Plant sterol has antioxidant activity, can provide hydrogen atom to stop the chain growth of oils and fats surface oxidation reaction.
Fructus Maydis oil has light local flavor and high stability, modern medicine proves, long-term edible corn germ oil has tangible clinical effectiveness to improving cardiovascular disease, Japan shows the result of study of Testa oryzae oil, Oleum Helianthi and Fructus Maydis oil, the three to the reduction rate of human serum cholesterol be respectively 18%, 13%HE and 16%.The corn refined oil was once sold in the pharmacy as health care oil for a long time.Except that rising aspect cardiovascular disease the preventive effect, Fructus Maydis oil also embodies certain function in the control of keratitis, nyctalopia.This is the result of physiologically active ingredient comprehensive functions such as rational fatty acid composition, high-load relatively vitamin E and plant sterol.
Modern scientific research shows that generation, the antitumor of anti-oxidation function and slow down aging, minimizing disease all have close getting in touch.Along with going deep into of social economy's construction, the raising of living standards of the people, more and more urgent to the pursuit of high quality of the life.For this reason, people are managing to seek a kind of material with comprehensive anti-oxidation function, the state so that health is kept fit always.
Though the pill of vitamin E and the production marketing of sterols are arranged on the market, and the overwhelming majority only contains single composition in them.At Japan Patent JP60149367, " a kind of capsule that contains the viscose glue extract " disclosed, be to contain vitamin E.At British patent EP1161884, " a kind of living power food supply based on nicotinamide adenine dinucleotide, the pure and mild vitamin E of octacosane " disclosed, it is the oral liquid through emulsification.They all do not use Fructus Maydis oil, beta-carotene, sterol etc., its function singleness.
Three, summary of the invention
The objective of the invention is in order to prepare in a kind of reaction of removing free radical in vivo, antioxidant is in close relations, vitamin E can put out multiple free radical, and the direct and reactive oxygen species of beta-carotene energy, the pure and mild plant sterol of octacosane also all has anti-oxidation characteristics separately, this collaborative performance antioxidation efficiency ratio single component with better function more fully, has the oxidation-resisting health-care nutritional oil.
The technical scheme that is adopted is in the present invention, and is formulated by following composition, octacosanol 2.1-2.5mg, beta-carotene 10-20mg, sterol 30-80mg, vitamin e1 01-120IU, Fructus Maydis oil 350-397mg.
In the present invention the sterol that is adopted be from soybean oil processing and by-product, the secondary alcohol that makes by solvent crystallization, drying.People do not have to occur normal healthy human body can not found toxic reaction on one's body at experimental animal because of the adverse effect that absorbs in the body of plant sterol, metabolism produces yet to studies show that the safety of sterol is carried out.The quality standard of sterol used in the present invention is (FAO/WHO, 1993):
The vitamin E that is adopted is to extract from Semen sojae atricolor with molecularly distilled to form in the present invention, and vitamin E and blood plasma cholesterol level have stronger dependency.People such as Qureshi (1992) have studied the influence of each isomer of vitamin E to the chicken of trouble hypercholesterolemia, find that each isomer of vitamin E all has the function of cholesterol reducing.
Vitamin E at first is to be applied in medicine and the food industry, and its safety just becomes the problem that people extremely pay close attention to.Generally speaking, human body can tolerate megavitamin E well, and the adult can take 200～800mg tocopherol equivalent and can not produce harmful effect every day.At present, in the U.S., select every day the best intake in meals of 100～400IU as vitamin E, the recommended amounts of this standard is based on all that to avoid taking place chronic disease dangerous and improve that wholesome results of study such as body immune function advocate.Its quality conformance with standard of vitamin E that the present invention uses.
China health care association thinks that beta-carotene can do edible health food.The beta-carotene that the present invention adopts extracts from fermentation liquid.Beta-carotene can change into vitamin A in human body, so also be called by people " provitamin A ".So carotene has the function of vitamin A, promptly have the health of keeping epithelial tissue, keep normal vision, promote growth and improve effects such as immunity.In addition, carotene also has the effect of unexistent better antioxidation of vitamin A and prevention canceration.
Vitamin A can not eat in a large number.Because it can store in vivo, be difficult for discharging, savings is many just may poison.And carotene can not be poisoned.
The octacosanol that is adopted is the by-product that gets from Testa oryzae oil processing, by the higher alcohol that uses extraction and solvent crystallization to make in the present invention.People have carried out particular study to the toxicity of octacosanol, and confirm that by acute toxicity test the white mouse median lethal dose(LD 50) is LD
50=18000mg/kg (white mouse is oral), safety is than the also high (LD of Sal of the safety of Sal
50=3000mg/kg).Zhejiang Medical university Yan Jixiang professor's demonstration has also confirmed this point.The quality standard of octacosanol used in the present invention is:
Molecular formula: CH
3(CH2)
26CH
2OH
Relative molecular weight: 410
Outward appearance: white powder
Moisture and volatile matter content :≤0.5%
Ash :≤0.4%
Content: 〉=12-90% (GC detection) (complete in specifications)
Total pure content: 〉=98%
Content of beary metal: plumbous (Pb)≤10mg/kg
Arsenic (As)≤1.5% (mg/kg)
Microorganism detection: total number of bacteria≤3000cfu/g
Escherichia coli: must not detect
Fusing point: 80～83 ℃
Sieve mesh is analyzed: 80 orders
The Fructus Maydis oil that is adopted is to extract the edible oil and fat that form through refine from Fructus Maydis in the present invention.Fatty acid in the Fructus Maydis oil mainly is linoleic acid (32%～62%), oleic acid (19%～50%) and Palmic acid (8%～19%).Linolenic content is about 0.3%～2.7%, scarcely surpasses 1%, because extremely low linolenic acid level and lauric shortage in the Fructus Maydis oil makes it can show stability highly to hydrolysis or antioxidation at duration of storage.Modern medicine proves that long-term edible corn germ oil has tangible clinical effectiveness to improving cardiovascular disease.The quality of employed Fructus Maydis oil meets national refining of edible standard in the present invention.
Preparing process in the present invention is, after at first sterol, vitamin E, beta-carotene, octacosanol, Fructus Maydis oil being prepared according to certain weight ratio, putting into crucible stirs, after the soft capsule molding is packed in injection into, again through pelleting, typing, drying, be packaged into bottle after choosing operation such as ball and get final product.
The edible product of making by the present invention, its method be, edible 2 times of every day, breakfast and dinner each once, each 2, every 500mg.
The finished product of gained of the present invention has preparation simply, and compatibility is precise and appropriate, brings out the best in each other, and characteristics such as taking convenience are a kind of nutritional oil that is particularly suitable for taking for a long time.
Four, the specific embodiment
Further specify the present invention below in conjunction with three embodiments, specific as follows:
Embodiment 1 sterol 30mg, beta-carotene 11mg, octacosanol 2.1mg, vitamin e1 01IU, Fructus Maydis oil 355mg.
Embodiment 2 sterol 50mg, 15'-dioxygenase mg, octacosanol 2.3mg, vitamin e1 10IU, Fructus Maydis oil 360mg.
Embodiment 3 sterol 70mg, beta-carotene 19mg, octacosanol 2.4mg vitamin e1 15IU, Fructus Maydis oil 370mg.
Claims (1)
1. one kind has the oxidation-resisting health-care nutritional oil, it is characterized in that by following composition preparation: octacosanol 2.1-2.5mg, beta-carotene 10-20mg, sterol 30-80mg, vitamin e1 01-120IU, Fructus Maydis oil 350-397mg.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 200410022627 CN1255167C (en) | 2004-05-25 | 2004-05-25 | Anti-oxidation health care nutrient oil |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 200410022627 CN1255167C (en) | 2004-05-25 | 2004-05-25 | Anti-oxidation health care nutrient oil |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1583019A true CN1583019A (en) | 2005-02-23 |
| CN1255167C CN1255167C (en) | 2006-05-10 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 200410022627 Expired - Fee Related CN1255167C (en) | 2004-05-25 | 2004-05-25 | Anti-oxidation health care nutrient oil |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112889933A (en) * | 2021-03-09 | 2021-06-04 | 汪智强 | Health-care nutrient oil with functions of resisting fatigue and reducing blood fat |
| CN113016887A (en) * | 2021-03-09 | 2021-06-25 | 汪智强 | Antioxidant health-care nutritional oil |
-
2004
- 2004-05-25 CN CN 200410022627 patent/CN1255167C/en not_active Expired - Fee Related
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112889933A (en) * | 2021-03-09 | 2021-06-04 | 汪智强 | Health-care nutrient oil with functions of resisting fatigue and reducing blood fat |
| CN113016887A (en) * | 2021-03-09 | 2021-06-25 | 汪智强 | Antioxidant health-care nutritional oil |
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| Publication number | Publication date |
|---|---|
| CN1255167C (en) | 2006-05-10 |
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Granted publication date: 20060510 |