CN1566091A - Molindone derivatives and use for preparing antineoplastic medicine thereof - Google Patents
Molindone derivatives and use for preparing antineoplastic medicine thereof Download PDFInfo
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- CN1566091A CN1566091A CN 03146229 CN03146229A CN1566091A CN 1566091 A CN1566091 A CN 1566091A CN 03146229 CN03146229 CN 03146229 CN 03146229 A CN03146229 A CN 03146229A CN 1566091 A CN1566091 A CN 1566091A
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- compound
- indolone
- compounds
- piperidine
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- 230000000118 anti-neoplastic effect Effects 0.000 title abstract 2
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Abstract
Description
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CNB031462294A CN1295216C (en) | 2003-07-04 | 2003-07-04 | Molindone derivatives and use for preparing antineoplastic medicine thereof |
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Cited By (9)
Publication number | Priority date | Publication date | Assignee | Title |
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WO2006032164A1 (en) * | 2004-09-23 | 2006-03-30 | Beijing Molecule Science And Technology Co., Ltd. | 1,3-substitued-2-indolinone derivatives, the preparation, the composition and the use thereof |
WO2012119506A1 (en) * | 2011-03-10 | 2012-09-13 | 中国人民解放军军事医学科学院毒物药物研究所 | Indolone derivatives, pharmaceutical compositions thereof, and preparation methods and applications thereof |
CN103274988A (en) * | 2013-06-20 | 2013-09-04 | 河北大学 | 3-(cyano-p-nitrobenzene methylene)-2-indolone derivative and synthesis method and application thereof |
CN104211632A (en) * | 2013-05-31 | 2014-12-17 | 中国人民解放军军事医学科学院放射与辐射医学研究所 | 2-Indolone derivative with tyrosine kinase inhibition activity, and preparation method and application thereof |
CN104387378A (en) * | 2014-11-24 | 2015-03-04 | 沈阳药科大学 | New 4-thiazolidone derivative and application thereof |
CN104693194A (en) * | 2015-01-30 | 2015-06-10 | 贵州大学 | 3-(2-acrylate)-3'-nitroisoxazole oxoindole compound as well as preparation method and application thereof |
CN108251104A (en) * | 2018-02-27 | 2018-07-06 | 山东大学 | A kind of substituted indole -2- carboxylic acids Bcl-2 small-molecule fluorescent probes and its application |
CN112155625A (en) * | 2020-08-31 | 2021-01-01 | 广东工业大学 | Medicine-carrying degradable blood vessel anastomat |
CN114213396A (en) * | 2022-01-27 | 2022-03-22 | 深圳市乐土生物医药有限公司 | Indole-2-ketone compound and preparation method and application thereof |
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US3733321A (en) * | 1971-07-06 | 1973-05-15 | Squibb & Sons Inc | 1,4-benzothiazin-3-ones |
US5322950A (en) * | 1991-12-05 | 1994-06-21 | Warner-Lambert Company | Imidazole with angiotensin II antagonist properties |
RU2145852C1 (en) * | 1996-01-17 | 2000-02-27 | Тайхо Фармасьютикал Ко., Лтд | Inhibitor of intima hypertrophy, use of hydroxyindole derivative for synthesis of inhibitor of intima hypertrophy, compositions for inhibition of intima hypertrophy, method of prophylaxis and treatment of intima hypertrophy |
HN1997000027A (en) * | 1996-12-06 | 1997-06-05 | Pfizer Prod Inc | DERIVATIVES OF 6-PHENYL PIRIDIL - 2 AMINE |
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2003
- 2003-07-04 CN CNB031462294A patent/CN1295216C/en not_active Expired - Fee Related
Cited By (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2006032164A1 (en) * | 2004-09-23 | 2006-03-30 | Beijing Molecule Science And Technology Co., Ltd. | 1,3-substitued-2-indolinone derivatives, the preparation, the composition and the use thereof |
WO2012119506A1 (en) * | 2011-03-10 | 2012-09-13 | 中国人民解放军军事医学科学院毒物药物研究所 | Indolone derivatives, pharmaceutical compositions thereof, and preparation methods and applications thereof |
CN102675292A (en) * | 2011-03-10 | 2012-09-19 | 中国人民解放军军事医学科学院毒物药物研究所 | Indolone derivative, medicinal composition thereof and preparation method and application of indolone derivative |
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CN104211632A (en) * | 2013-05-31 | 2014-12-17 | 中国人民解放军军事医学科学院放射与辐射医学研究所 | 2-Indolone derivative with tyrosine kinase inhibition activity, and preparation method and application thereof |
CN103274988B (en) * | 2013-06-20 | 2016-04-13 | 河北大学 | 3-(cyano group-p-nitrobenzoyl support group)-2-indolone derivatives and preparation method and use thereof |
CN103274988A (en) * | 2013-06-20 | 2013-09-04 | 河北大学 | 3-(cyano-p-nitrobenzene methylene)-2-indolone derivative and synthesis method and application thereof |
CN104387378A (en) * | 2014-11-24 | 2015-03-04 | 沈阳药科大学 | New 4-thiazolidone derivative and application thereof |
CN104693194A (en) * | 2015-01-30 | 2015-06-10 | 贵州大学 | 3-(2-acrylate)-3'-nitroisoxazole oxoindole compound as well as preparation method and application thereof |
CN104693194B (en) * | 2015-01-30 | 2017-07-11 | 贵州大学 | 3 (2 acrylate) 3 ˊ nitro isoxazole Oxoindole compounds and preparation method and application |
CN108251104A (en) * | 2018-02-27 | 2018-07-06 | 山东大学 | A kind of substituted indole -2- carboxylic acids Bcl-2 small-molecule fluorescent probes and its application |
CN112155625A (en) * | 2020-08-31 | 2021-01-01 | 广东工业大学 | Medicine-carrying degradable blood vessel anastomat |
CN114213396A (en) * | 2022-01-27 | 2022-03-22 | 深圳市乐土生物医药有限公司 | Indole-2-ketone compound and preparation method and application thereof |
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