CN1530179A - Cleaning processing method and apparatus for medical or medicinal rubber stopper - Google Patents
Cleaning processing method and apparatus for medical or medicinal rubber stopper Download PDFInfo
- Publication number
- CN1530179A CN1530179A CNA031158218A CN03115821A CN1530179A CN 1530179 A CN1530179 A CN 1530179A CN A031158218 A CNA031158218 A CN A031158218A CN 03115821 A CN03115821 A CN 03115821A CN 1530179 A CN1530179 A CN 1530179A
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- Prior art keywords
- hole
- rubber stopper
- medical
- water
- water spraying
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Abstract
A method and equipment for washing the medical or medicinal rubber plugs features that the high-pressure liquid stream is used to flush said rubber plugs downward, so the rubber plugs are cleaned in semi-suspended or suspended state. Its equipment is composed of container with multiple water spraying holes on its bottom and side wall, washing drum, water storage, water inlet pipe, water outlet pipe, and the pressurizing pump and pressure regulating valve for spraying the cleaning liquid from water spraying holes.
Description
Technical field
The present invention relates to a kind of cleaning treatment method and device that can effectively reduce the medical or medicinal rubber stopper of surperficial particulate matter.
Background technology
Current rubber stopper (hereinafter to be referred as plug) with vulcanized rubber (comprising the various vulcanizates based on butyl rubber, natural rubber, isoamyl glue, acrylonitrile-butadiene rubber etc.) is widely used in the peristome of the medical or pharmaceutical containers of shutoff, this is because the rubber high resilience can produce functions such as remarkable sealing, shroud of gas, anti-acupuncture to the content of container.But because its technological process of production will comprise multiple working procedures such as mixing, moulding, sulfuration, die-cut, deburring, check, packing, the plug surface is very easy in the handover process of each procedure adheres to and is infected with various insoluble impurities particulates.For content medical or that pharmaceutical containers held,, can't permit the contamination of this based fine particles owing to maintaining the health even the life of human body.Before in the end packing, medical for this reason or medical rubber plug all to pass through washing procedure, to remove surperficial particulate matter.
Cleaning method at present commonly used has two kinds of roller and basket-hangings.
Roller is in a container that holds certain water gaging or cleaning solution, a rotating drum is set, arranges on the drum wall and can supply water or hole that cleaning solution flows through, plug is placed in the drum, by the rotation of drum in water or cleaning solution, reach the purpose of cleaning.This method utilization is arranged on the valve of container bottom, can be according to water and the cleaning solution in the needs of the technology transposing container, thereby can be to repeatedly cleaning with batch plug.The shortcoming of this method is: 1, impurity content and density unevenness are even in water in the drum or the cleaning solution; Plug was in contact with one another friction when 2, drum rotated, and produced new particulate matter; But though 3, water or cleaning solution reflux and filter after cleaning, removal of contamination is to the pollution once more of plug fully.
Basket-hanging is to arrange side by side that several hold the container of clear water or cleaning solution, and plug places and hangs indigo plant, by hanging basket in each container one by one lixiviate move, finish the washing and cleaning operation of plug.Though this method can avoid plug to be in contact with one another the friction and the repeated contamination of cleaning fluid, still, its shortcoming is, 1, plug immerses in the cleaning fluid under static conditions, and whole cleaning performance is undesirable; 2, inconsistent in hanging basket centre and border area cleaning performance between the two, particularly the plug at zone line can not get effective washing.
Summary of the invention
Because the shortcoming of above-mentioned cleaning method and device, the present invention aim to provide a kind of in cleaning process plug can not be in contact with one another cleaning treatment method and the device that friction can wash away and take away the medical or medicinal rubber stopper of particulate matter again with dynamic current flow.
The present invention system is characterized in that based on the principle that the liquid that adopts band pressure impacts washing, adopts high pressure liquid stream to wash away rubber stopper from bottom to top, makes rubber stopper finish cleaning treatment when being in half suspension and suspended state.
For this reason specialized designs by the device of the medical or medicinal rubber stopper of this cleaning treatment principle cleaning treatment, constitute and comprise container, washing tank, water butt, water inlet pipe, outlet pipe, it is characterized in that, the bottom of described container and side wall array hole for water spraying, the bottom also is placed with backflash or return port.When cleaning plug, plug places in the washing tank, from the cleaning solution of water inlet pipe inflow, after the booster pump supercharging, act on plug from the liquid stream of water jet ejection band certain pressure, make plug be subjected to washing away, constantly be in half and suspend and suspended state, simultaneously by backflash or return port from the fluid power of bottom and side, install after filtration, extract out by the liquid of suction pump after, return water storing tank, recycle Washing.Discharge for the liquid stream after making particulate matter with washing, avoid polluting once more plug, guarantee to clean thoroughly, on inlet pipeline, connect pressure regulator valve, can regulate pressure regulator valve, make feed liquor flow V
1≤ go out flow quantity V
2
Container can be cylinder and the cube of bottom for arc and plane, and for the flow stream pressure that makes ejection is evenly distributed, the hole for water spraying that is arranged in its bottom and sidewall should be staggered, and the distance between borehole between the hole for water spraying is represented to be preferably with three hole inscribe diameter of a circles:
Bottom hole for water spraying pitch of holes: D
1=1/4d
1～3/4d
1,
Sidewall hole for water spraying pitch of holes: D
2=d
1～3d
1,
The hole for water spraying aperture is preferably: D
3=1/10d
1～3d
1
In the formula: D
1---three hole inscribed circle diameters in the bottom;
D
2---at three hole inscribed circle diameters of sidewall;
D
3---the hole for water spraying aperture;
d
1---the biggest size of element of plug.
The hole for water spraying pitch of holes is too small, causes backflash and return port to be difficult for arranging, so that discharge opeing is not smooth, otherwise pitch of holes is excessive, can cause hydraulic pressure not enough and uneven, even plug can not be in half suspension and suspended state.The hole for water spraying aperture is excessive or too smallly all can cause the flow stream pressure deficiency, can not make plug be in desirable half and suspend and suspended state, so that cleaning performance is affected.
For the particulate matter that washes away is taken away by liquid stream smoothly, arrange in the bottom of container backflash or return port, the groove width H of backflash
1Or the aperture D of return port
4Be preferably::
Groove width H
1=1/4h
1～3/4h
1,
Aperture D
4=1/4d
2～3/4d
2,
In the formula: h
1---the plug height;
d
2---the glue stopper neck physical dimension.
According to apparatus and method of the present invention, its effect is conspicuous, that is:
1, plug is subjected to washing away of certain pressure liquid stream and washes, and can effectively reach the effect of flush away insoluble impurities particulate;
2, plug constantly is in half suspension and suspended state, is subjected to the impact from bottom and side liquid stream simultaneously, and under dynamic situation, the plug surface can evenly be washed, and every batch of cleaning performance is even;
3, be in half at the effect bottom plug of liquid stream scouring force and suspend and suspended state, significantly reduce it and be in contact with one another friction and the chance that produces new contaminant particles;
4, the liquid after the washing is forced to extract out and discharges, and takes away the contaminant particles of getting off from surface washing, has avoided the pollution once more to plug.
Description of drawings
Fig. 1 is apparatus of the present invention schematic diagrames;
Fig. 2 is the schematic top plan view of container 1 bottom among Fig. 1;
Fig. 3 is the schematic diagram that expression hole for water spraying pitch of holes is arranged.
Number in the figure is: 1---container; 2---washing tank; 3---the water inlet interlayer; 4---go out water tray; 5,9,10---pressure regulator valve; 6---outlet pipe; 7---filter; 8---suction pump; 10---booster pump; 12---water inlet pipe; 14---hole for water spraying; 15---backflash; 16---water spray aperture (D
1, D
2); 17---three hole inscribed circle diameter (D
3);
" ↑ " expression water inlet liquid stream among the figure, " ↓ " expression water outlet liquid stream.
The specific embodiment
The invention will be further described below in conjunction with embodiment, but the present invention never is confined to these
Embodiment.
Embodiment 1
Referring to Fig. 1, Fig. 2 and Fig. 3.
Adopt device shown in Figure 1, its formation comprises, container 1, washing tank 2, water butt 13, water inlet pipe 12, outlet pipe 6.Container 1 is the cylinder of diameter D=800mm, its bottom and side wall array hole for water spraying 14, the aperture D of hole for water spraying
1=15mm, D
2=40mm; The pitch of holes D of hole for water spraying
3=6mm is provided with three backflashes 15, groove width H in the bottom of container 1
1=8mm.The clean water (deionized water) that flows out from water storing tank 13 enters container 1 and flows ejection from hole for water spraying 14 with the liquid of being with certain pressure after water inlet pipe 12 and booster pump 10 superchargings, liquid after the washing is collected in the draining tray through backflash, return water storing tank through outlet pipe 6, filter 7, suction pump 10, reuse.The cephalosporin analog antibiotic plug of in the washing tank 2 of this device, packing into, every batch is 30kg, the physical dimension of plug is d
1=19mm; d
2=13mm; h
1=8.5mm.Regulate pressure regulator valve 9, make plug be in half and suspend and suspended state, regulate pressure regulator valve 5,11 and make sidewall water spray distance greater than 1/2D.The pump-out of regulating suction pump makes flow of inlet water V
1≤ water flow V
2Scavenging period 20 minutes, products obtained therefrom surface insoluble impurities particle test result and the comparison such as the table 1 that adopt roller cleaning device and method.
Table 1
| Particle diameter | Particle number is (individual/10cm 2) | |
| The inventive method | Roller | |
| ????≥10μm | ????68 | ????212 |
| ????≥25μm | ????6 | ????17 |
Cleaning device and method are with embodiment 1.Be used for the two fork of cleaning treatment freeze dried vaccine plug, every batch processing amount 30kg.Plug physical dimension: d
1=19mm; d
2=13.5mm; h
1=9.2mm.Scavenging period 25 minutes.Products obtained therefrom surface insoluble impurities particle test result and the comparison such as the table 2 that adopt roller cleaning device and method.
Table 2
| Particle diameter | Particle number is (individual/10cm 2) | |
| The inventive method | Roller | |
| ????≥10μm | ????86 | ????314 |
| ????≥25μm | ????8 | ????28 |
Claims (8)
1. the cleaning treatment method of a medical or medicinal rubber stopper is characterized in that, adopts high pressure liquid stream to wash away rubber stopper from bottom to top, make rubber stopper be in half suspend and suspended state in finish cleaning treatment.
2. the device of medical or medicinal rubber stopper cleaning treatment method according to claim 1, constitute and comprise container 1, washing tank 2, water butt 13, water inlet pipe 12, outlet pipe 6, it is characterized in that, the bottom of described container 1 and side wall array hole for water spraying 14, bottom also are placed with backflash and return port 15.
3. medical or medicinal rubber stopper cleaning processing apparatus according to claim 2 is characterized in that, described hole for water spraying 14 interlaced arranging.
4. medical or medicinal rubber stopper cleaning processing apparatus according to claim 2 is characterized in that, described hole for water spraying 14 is respectively with pitch of holes and the aperture thereof that three hole inscribed circles calculate:
Bottom hole for water spraying pitch of holes: D
1=1/4 d
1～3/4d
1,
Sidewall hole for water spraying pitch of holes: D
2=d
1～3d
1,
Hole for water spraying aperture: D
3=1/10d
1～3d
1
In the formula: D
1---three hole inscribed circle diameters in the bottom;
D
2---at three hole inscribed circle diameters of sidewall;
D
3---the hole for water spraying aperture;
d
1---the biggest size of element of plug.
5. medical or medicinal rubber stopper cleaning processing apparatus according to claim 2 is characterized in that, arrange in the bottom of container 1 backflash or return port 15.
6. medical or medicinal rubber stopper cleaning processing apparatus according to claim 2 is characterized in that, described backflash groove width or return port aperture are:
Groove width H
1=1/4h
1～3/4h
1,
Aperture D
4=1/4d
2～3/4d
2,
In the formula: h
1---the plug height;
d
2---the glue stopper neck physical dimension.
7. medical or medicinal rubber stopper cleaning processing apparatus according to claim 2 is characterized in that, described water inlet pipe 12 connects booster pump 10 and pressure regulator valve 5,9,11, and described outlet pipe 6 connects filter 7 and suction pump 8.
8. the using method of medical or medicinal rubber stopper cleaning treatment method and apparatus according to claim 1 and 2 is characterized in that, regulates flow of inlet water V during use
1≤ water flow V
2
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNA031158218A CN1530179A (en) | 2003-03-14 | 2003-03-14 | Cleaning processing method and apparatus for medical or medicinal rubber stopper |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNA031158218A CN1530179A (en) | 2003-03-14 | 2003-03-14 | Cleaning processing method and apparatus for medical or medicinal rubber stopper |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN1530179A true CN1530179A (en) | 2004-09-22 |
Family
ID=34284451
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNA031158218A Pending CN1530179A (en) | 2003-03-14 | 2003-03-14 | Cleaning processing method and apparatus for medical or medicinal rubber stopper |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN1530179A (en) |
Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN100355510C (en) * | 2005-04-13 | 2007-12-19 | 刘元顺 | Suspension type strong water-air rubber plug cleaning machine |
| CN103028569A (en) * | 2012-12-14 | 2013-04-10 | 湖北关公坊酒业股份有限公司 | Bottle stopper cleaning machine |
| CN103111435A (en) * | 2013-03-06 | 2013-05-22 | 楚天科技股份有限公司 | Cleaning system and cleaning method for rubber plug cleaning machine |
| CN104858170A (en) * | 2015-05-11 | 2015-08-26 | 成都中牧生物药业有限公司 | Improved structure of rubber plug cleaning machine based on completely-cleaned inner wall of rubber plug |
| CN104889094A (en) * | 2015-05-11 | 2015-09-09 | 成都中牧生物药业有限公司 | Full-automatic rubber plug cleaning equipment |
| CN105137051A (en) * | 2015-09-15 | 2015-12-09 | 湖北华强科技有限责任公司 | Infusion rubber plug and medicine compatibility fast evaluation method |
| CN117403237A (en) * | 2023-12-14 | 2024-01-16 | 中实强业(山西)新材料科技有限公司 | Ball opening type aluminum hole surface cleaning finishing device |
-
2003
- 2003-03-14 CN CNA031158218A patent/CN1530179A/en active Pending
Cited By (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN100355510C (en) * | 2005-04-13 | 2007-12-19 | 刘元顺 | Suspension type strong water-air rubber plug cleaning machine |
| CN103028569A (en) * | 2012-12-14 | 2013-04-10 | 湖北关公坊酒业股份有限公司 | Bottle stopper cleaning machine |
| CN103028569B (en) * | 2012-12-14 | 2015-01-28 | 湖北关公坊酒业股份有限公司 | Bottle stopper cleaning machine |
| CN103111435A (en) * | 2013-03-06 | 2013-05-22 | 楚天科技股份有限公司 | Cleaning system and cleaning method for rubber plug cleaning machine |
| CN103111435B (en) * | 2013-03-06 | 2014-12-17 | 楚天科技股份有限公司 | Cleaning system and cleaning method for rubber plug cleaning machine |
| CN104858170A (en) * | 2015-05-11 | 2015-08-26 | 成都中牧生物药业有限公司 | Improved structure of rubber plug cleaning machine based on completely-cleaned inner wall of rubber plug |
| CN104889094A (en) * | 2015-05-11 | 2015-09-09 | 成都中牧生物药业有限公司 | Full-automatic rubber plug cleaning equipment |
| CN105137051A (en) * | 2015-09-15 | 2015-12-09 | 湖北华强科技有限责任公司 | Infusion rubber plug and medicine compatibility fast evaluation method |
| CN117403237A (en) * | 2023-12-14 | 2024-01-16 | 中实强业(山西)新材料科技有限公司 | Ball opening type aluminum hole surface cleaning finishing device |
| CN117403237B (en) * | 2023-12-14 | 2024-02-23 | 中实强业(山西)新材料科技有限公司 | Ball opening type aluminum hole surface cleaning finishing device |
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|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C02 | Deemed withdrawal of patent application after publication (patent law 2001) | ||
| WD01 | Invention patent application deemed withdrawn after publication |