CN1528238A - Gastrointestinal biological electric information tracking therapeutic instrument - Google Patents
Gastrointestinal biological electric information tracking therapeutic instrument Download PDFInfo
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- CN1528238A CN1528238A CNA031350356A CN03135035A CN1528238A CN 1528238 A CN1528238 A CN 1528238A CN A031350356 A CNA031350356 A CN A031350356A CN 03135035 A CN03135035 A CN 03135035A CN 1528238 A CN1528238 A CN 1528238A
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Abstract
The present invention relates to a gastrointestinal bioelectric information following therapeutic equipment integrating gastrointestinal electric information detection and following therapy into one body. Said therapeutic equipment has the circuits of body surface detection, electric information collection, information processing conversion, following through and display. The output end of detector is connected with input end of collection circuit, the output end of the collection circuit is connected with input end of conversion circuit, and the output end of the conversion circuit is respectively connected with display circuit and input end of following technology circuit, and the output end of following therapy circuit is connected with detector. Said invention also provides its application method and its action.
Description
(1) technical field
The present invention relates to a kind of functional gastrointestinal disorder therapy equipment, especially collect the detection of gastrointestinal electrical information and follow the tracks of the gastrointestinal bio-electrical information tracking therapeutic instrument of treatment for one.
(2) background technology
As everyone knows, the person is numerous to suffer from the functional gastrointestinal disease, but most patient do not seek medical advice, or by Drug therapy, but medicining cycle is long, and foreseeable long-term efficacy is uncertain, and cure rate is not high, and the state of an illness is repeatedly; Also there is same problem in the treatment of other therapies.
Dissect and clinical experiment according to animal physiological, gastrointestinal smooth muscle has autorhythmicity, promptly under situation on an empty stomach, also can record spontaneous, slow, rhythmicity depolarization liquid, and promptly basic electrical rhythm (BER) also claims pacemaker current potential (PP) or slow wave.Gastrointestinal pacemaker tool " driving " and " following " effect (Driven and Following or Entrained Effects), the control gastrointestinal motility regularity.When stomach rhythm disturbance (GD), the frequency of clectrogastrogram, amplitude, the rhythm and pace of moving things change, and the stomach rhythm and pace of moving things can occur and overrun, cross the disorderly three kinds of situations that relax.BER is regulating and control time, frequency, position and the direction of gastrointestinal movement.The basic design that for this reason proposes gastrointestinal pacemaker is at gastrointestinal tract, as cardiac pacing, corrects gastrointestinal abnormal motion state.The bio-electrical information of simulation normal person gastrointestinal motility regularity is fed back to patient's gastrointestinal pacemaker, make patient's gastrointestinal motility regularity " follow " normal person's rule and wriggle, i.e. gastrointestinal pacemaker.Prove that now the ICC of myenteric nervous plexus (Interstitial Cell ofCajal) is exactly a gastrointestinal pacemaker cell, gastrointestinal pacemaker has its reliable form anatomical basis.
The inventor provides a kind of portable gastrointestinal electricity irritation electricity consumption therapeutic apparatus in the CN95118078.9 patent, comprise online programmable device, frequency display circuit, weighted resistance network, analog amplify circuit, output electrode and power supply.The online programmable device connects weighted resistance network and frequency display circuit, and the output of weighted resistance network exports body surface to through analog amplify circuit and sticks electrode, the power supply battery.Feed back to patient's gastrointestinal pacemaker according to the bio-electrical information of simulation normal person gastrointestinal motility regularity, make patient's gastrointestinal motility regularity follow normal person's gastric peristalsis, various gastrointestinal clinical symptoms are eased or disappear.Its function of gastrointestinal pacemaker is: treatment gastrointestinal neurosis, gastrointestinal rhythm disturbance syndrome, short intestinal absorption syndrome, postoperative gastric bowel dysfunction, gastroparesis, gastroptosis, irritable bowel syndrome and with the superficial gastritis of changing function etc.Because should invention only at clinical symptoms and no matter the electric rhythm and pace of moving things of the gastrointestinal peristalsis of above-mentioned symptom, so have significantly subjectivity and blindness.
(3) summary of the invention
The present invention aims to provide a kind of collection gastrointestinal electrical information and follows the tracks of treatment and is one, and the energy off line is carried out the gastrointestinal bio-electrical information tracking therapeutic instrument of data analysis.It is more advanced from the basic rhythm and pace of moving things of motion tracking detection more above-mentioned gastrointestinal pacemaker and various gastrointestinal disease therapeutic instrument, and curative effect is better.
Another object of the present invention is subjectivity and the blindness that overcomes the portable gastrointestinal pacemaker, shoots the arrow at the target, and adopts treatment functional gastrointestinal disease electricity pace-making type of drive.
The present invention is provided with gastrointestinal body surface detection device, gastrointestinal electrical information Acquisition Circuit, information processing translation circuit, follows the tracks of treatment circuit and display circuit.The input of the output termination gastrointestinal electrical information Acquisition Circuit of gastrointestinal body surface detection device, the input of the output termination information processing translation circuit of gastrointestinal electrical information Acquisition Circuit, the outfan of information processing translation circuit connects display circuit respectively and follows the tracks of the input of treatment circuit, follows the tracks of the output termination gastrointestinal electricity body surface detection device of treatment circuit.
Gastrointestinal electricity body surface detection device is used to gather the testing circuit that the gastrointestinal bio-electrical information offers gastrointestinal electrical information Acquisition Circuit on the one hand, be the tracking treatment signal of receive to follow the tracks of that the treatment circuit provides treated, standard, amplification on the other hand, and the patient is followed the tracks of treatment.
Gastrointestinal electrical information Acquisition Circuit is used for the filtering in addition of detected gastrointestinal bio-electrical information signal, amplification, and it is transformed to information processing translation circuit acceptable digital signal.
The information processing translation circuit is used for treating circuit and display circuit with collecting and pass through to differentiate, calculate and handle through analog-to-digital gastrointestinal bio-electrical information signal, deliver to follow the tracks of.
Display circuit be used to show collect with signal such as treatment parameter etc.
Following the tracks of the treatment circuit is used for the signal of telecommunication detected, gastrointestinal motility regularity through differentiating, calculate, handling, again through identification, standard, amplification, so that deliver to the therapeutic electrode of gastrointestinal body surface detection device.
Gastrointestinal body surface detection device comprises multifunctional electrodes and associate member and the connecting line of being made up of detecting electrode and therapeutic electrode.
Gastrointestinal electrical information Acquisition Circuit is provided with testing circuit, filter circuit, amplification matching circuit and A/D circuit, the gastrointestinal bio information detecting electrode outfan of the input termination multifunctional electrodes of testing circuit, the input of the output termination filter circuit of testing circuit, the input of the output termination amplification matching circuit of filter circuit, the input of the output termination A/D circuit of amplification matching circuit.
The information processing translation circuit is provided with CPU processor and operating means, and the digital signal input end of CPU processor connects the outfan of A/D circuit, and operating means connects the CPU processor, the output termination display circuit of CPU processor.
Following the tracks of the treatment circuit is provided with the treatment mode identificating circuit, follows the tracks of treatment waveform standard circuit and drive circuit, the outfan of the input termination CPU processor of treatment mode identificating circuit, the output termination of treatment mode identificating circuit is followed the tracks of the input of treatment waveform standard circuit, the tracking treatment information output (promptly following the tracks of the outfan of treatment waveform standard circuit) of following the tracks of the treatment circuit connects the input of drive circuit, the therapeutic electrode of the output termination multifunctional electrodes of drive circuit.
The present invention utilizes modern electronic technology, gather the gastrointestinal bio-electrical information from the body surface specific part, draw the gastrointestinal basic electrical rhythm and the characteristics of motion by analysis, the principle that the optimal stimulus frequency that adds according to gastrointestinal pacemaker should progressively be approached the normal electrical rhythm and pace of moving things, increasing or reduce a certain amount of frequency or intensity stimulates, treatment information takes place to follow the tracks of automatically, act on the gastrointestinal pacemaker through body surface, driving gastrointestinal electrical activity progressively moves to normal direction, thereby correct disorderly gastrointestinal motility rule, reach the purpose of radical cure functional gastrointestinal disease.Its maximum characteristics are subjectivity and the blindness that has overcome existing same categories of device such as portable gastrointestinal pacemaker; Secondly, it is one with following the tracks of treatment that the present invention gathers the gastrointestinal electrical information, and can off line carry out data analysis, detect, analyze basic electrical rhythm and feedback treating parameter from motion tracking, owing to abandoned conventional " zero level " sampling method, adopt the inventor to prove effective in long-term clinical practice, " piecewise analysis " and " analysis-by-synthesis " sampling method, therefore gastrointestinal pacemaker and the various gastrointestinal disease therapeutic instrument that has gone on the market at present is more advanced, and curative effect is better.
(4) description of drawings
Fig. 1 is that circuit of the present invention is formed block diagram.
Fig. 2 is that the circuit of the embodiment of the invention is formed block diagram.
Fig. 3,4 is embodiment of the invention circuit composition schematic diagram.
Fig. 5 is the multifunctional electrodes structural representation of the embodiment of the invention.
(5) specific embodiment
Following examples will the present invention is further illustrated in conjunction with the accompanying drawings.
As shown in Figure 1, the present invention is provided with gastrointestinal body surface detection device 1, gastrointestinal electrical information Acquisition Circuit 2, information processing translation circuit 3, follows the tracks of treatment circuit 4 and display circuit 5.The input of the output termination gastrointestinal electrical information Acquisition Circuit 2 of gastrointestinal body surface detection device 1, the input of the output termination information processing translation circuit 3 of gastrointestinal electrical information Acquisition Circuit 2, the outfan of information processing translation circuit 3 connects display circuit 5 respectively and follows the tracks of the input of treatment circuit 4, follows the tracks of the output termination gastrointestinal body surface detection device 1 of treatment circuit 4.
Gastrointestinal body surface detection device is used to gather the testing circuit that the gastrointestinal bio-electrical information offers gastrointestinal electrical information Acquisition Circuit on the one hand, be the tracking treatment signal of receive to follow the tracks of that the treatment circuit provides treated, standard, amplification on the other hand, and the patient is followed the tracks of treatment.
Gastrointestinal electrical information Acquisition Circuit is used for the filtering in addition of detected gastrointestinal bio-electrical information signal, amplification, and it is transformed to information processing translation circuit acceptable digital signal.
The information processing translation circuit is used for and will collects and pass through to differentiate, calculate and handle through analog-to-digital gastrointestinal bio-electrical information signal, and delivers to follow the tracks of and treat circuit and display circuit.
Display circuit be used to show collection with the treatment reference signal.
Tracking treatment circuit is used for the signal of telecommunication with the gastrointestinal motility regularity through differentiating, calculate, handling, again through identification, standard, amplification, so that deliver to the therapeutic electrode of gastrointestinal body surface detection device.
As shown in Figure 2, multifunctional electrodes and associate member and the connecting line formed by detecting electrode and therapeutic electrode of gastrointestinal body surface detection device 1.
Gastrointestinal electrical information Acquisition Circuit 2 is provided with testing circuit 21, filter circuit 22, amplification matching circuit 23 and A/D circuit 24, the gastrointestinal bio information detecting electrode outfan of the input termination multifunctional electrodes of testing circuit 21, the input of the output termination filter circuit 22 of testing circuit 21, the input of the output termination amplification matching circuit 23 of filter circuit 22, the input of the output termination A/D circuit 24 of amplification matching circuit 23.
Information processing translation circuit 3 is provided with CPU processor 31 and operating means 32, and the digital signal input end of CPU processor connects the outfan of A/D circuit, and operating means connects the CPU processor, the output termination display circuit of CPU processor.
Following the tracks of treatment circuit 4 is provided with treatment mode identificating circuit 41, follows the tracks of treatment waveform standard circuit 42 and drive circuit 43, the outfan of the input termination CPU processor 31 of treatment mode identificating circuit 41, the output termination of treatment mode identificating circuit 41 is followed the tracks of the input of treatment waveform standard circuit 42, the tracking treatment information output (promptly following the tracks of the outfan of treatment waveform standard circuit 42) of following the tracks of treatment circuit 4 connects the input of drive circuit 43, the therapeutic electrode of the output termination multifunctional electrodes of drive circuit 43.
In sum, the present invention is made up of following three parts basically:
1) signal deteching circuit: the electric rhythm and pace of moving things small-signal of picking up gastrointestinal peristalsis by the detecting electrode in the multifunctional electrodes, filter circuit is sent in the circuit amplification after testing, take out the useful signal of telecommunication that meets gastrointestinal motility regularity, this signal is sent into amplification matching circuit, amplification also reaches setting, send into the A/D circuit and carry out analog digital conversion, be about to analogue signal and become digital signal, then digital signal is sent into central processing unit (CPU) conversion process.
2) follow the tracks of the treatment circuit: the result who draws by central processing unit (CPU), it is the signal of telecommunication of gastrointestinal peristalsis, send into the treatment mode identificating circuit, best pacing parameter is determined in identification, and after standardization, send into drive circuit and amplify, the signal that will amplify is then delivered to the therapeutic electrode in the multifunctional electrodes.
3) signal processing translation circuit: the signal processing translation circuit is born by CPU, sends into CPU from the signal that gastrointestinal collects through analog digital conversion, calculates through differentiating, and the result sends into display circuit, sends into the treatment mode identificating circuit simultaneously and goes to follow the tracks of treatment.
Multifunctional electrodes is to integrate signal detection and signal to drive and provide and overcome the interfering signal measure.Testing circuit is that the signal that will send here from multifunctional electrodes is amplified, filter circuit only allows the gastrointestinal electrical information to pass through, other signal does not allow to pass through, amplification matching circuit is that the signal that wave circuit amplitude after filtration diminishes is amplified again, and make power reach standardized output signal, the A/D circuit becomes digital signal with analog signal conversion, the treatment mode identificating circuit is determined the frequency and the amplitude of best pacing therapy, follow the tracks of treatment standard circuit drive current is adjusted to the degree of suitable patient treatment, drive circuit has enlarging function and can mate with different patients' skin resistance, it is circuit software executive circuit that information conversion is handled, and understands and handle gastrointestinal motility regularity.
As Fig. 3, shown in 4, concrete signal flow is: detection signal enters IC 1 preposition amplification by multifunctional electrodes, sending into the IC2 in-phase end more further amplifies, carrying out the intestines and stomach signal at the output resistance R7 of IC2 node separates, by resistance R 7-R11 and integrated circuit, the signal of capacitor C 6-C9 and IC 3 is the gastric peristalsis regularity signals, by resistance R 18-R34, capacitor C 14-C21 and IC 6, the signal of IC7 is the enterokinesia regularity signals, stomach electricity rhythm and pace of moving things signal is by the in-phase end of C10 input ic IC4,7 foot outfan CNO by IC 5 send into analog-digital converter, intestinal electricity rhythm and pace of moving things signal is input to the in-phase end of IC 8 by capacitor C 22,7 foot outfan CN1 by IC 9 send into analog-digital converter, CN0, CN1 sends into A/D circuit zero passage and 1 passage.CPU is born by integrated circuit 8052, and the gastrointestinal signal of telecommunication of understanding through CPU outputs to digital to analog converter D/A, and IC 10 is sent in the analog quantity output of D/A, and goes the pace-making gastrointestinal peristalsis by the therapeutic electrode that the output A of IC 11 connects multifunctional electrodes.
The 10th, 11 feet by CPU connect the LCD display circuit.
Referring to Fig. 5, multifunctional electrodes is made up of silver chloride electrode (detecting electrode) 11 and stainless steel alloy (therapeutic electrode) 12, and polyethylene isolation layer 13 is arranged therebetween.Silver chloride electrode connects the 2nd, 3 feet of IC1 respectively, and therapeutic electrode connects polyethylene isolation layer 13.
Claims (5)
1, the gastrointestinal bio-electrical information is followed the tracks of therapeutic instrument, it is characterized in that being provided with gastrointestinal body surface detection device, gastrointestinal electrical information Acquisition Circuit, information processing translation circuit, follows the tracks of treatment circuit and display circuit; The input of the output termination gastrointestinal electrical information Acquisition Circuit of gastrointestinal body surface detection device, the input of the output termination information processing translation circuit of gastrointestinal electrical information Acquisition Circuit, the outfan of information processing translation circuit connects display circuit respectively and follows the tracks of the input of treatment circuit, follows the tracks of the output termination gastrointestinal body surface detection device of treatment circuit.
2, gastrointestinal bio-electrical information as claimed in claim 1 is followed the tracks of therapeutic instrument, it is characterized in that the multifunctional electrodes that gastrointestinal body surface detection device is made up of detecting electrode and therapeutic electrode.
3, gastrointestinal bio-electrical information as claimed in claim 1 is followed the tracks of therapeutic instrument, it is characterized in that gastrointestinal electrical information Acquisition Circuit is provided with testing circuit, filter circuit, amplification matching circuit and A/D circuit, the gastrointestinal bio information detecting electrode outfan of the input termination multifunctional electrodes of testing circuit, the input of the output termination filter circuit of testing circuit, the input of the output termination amplification matching circuit of filter circuit, the input of the output termination A/D circuit of amplification matching circuit.
4, gastrointestinal bio-electrical information as claimed in claim 1 is followed the tracks of therapeutic instrument, it is characterized in that the information processing translation circuit is provided with CPU processor and operating means, the digital signal input end of CPU processor connects the outfan of A/D circuit, operating means connects the CPU processor, the output termination display circuit of CPU processor.
5, gastrointestinal bio-electrical information as claimed in claim 1 is followed the tracks of therapeutic instrument, it is characterized in that following the tracks of the treatment circuit is provided with the treatment mode identificating circuit, follows the tracks of treatment waveform standard circuit and drive circuit, the outfan of the input termination CPU processor of treatment mode identificating circuit, the output termination of treatment mode identificating circuit is followed the tracks of the input of treatment waveform standard circuit, the tracking treatment information output (promptly following the tracks of the outfan of treatment waveform standard circuit) of following the tracks of the treatment circuit connects the input of drive circuit, the therapeutic electrode of the output termination multifunctional electrodes of drive circuit.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 03135035 CN1233297C (en) | 2003-09-29 | 2003-09-29 | Gastrointestinal biological electric information tracking therapeutic instrument |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 03135035 CN1233297C (en) | 2003-09-29 | 2003-09-29 | Gastrointestinal biological electric information tracking therapeutic instrument |
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| CN1528238A true CN1528238A (en) | 2004-09-15 |
| CN1233297C CN1233297C (en) | 2005-12-28 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN 03135035 Expired - Fee Related CN1233297C (en) | 2003-09-29 | 2003-09-29 | Gastrointestinal biological electric information tracking therapeutic instrument |
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Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101961238A (en) * | 2010-10-09 | 2011-02-02 | 王光强 | Peristalsis monitor |
| CN105617530A (en) * | 2016-03-02 | 2016-06-01 | 西安交通大学第一附属医院 | Digital gastrointestinal pacemaker |
| CN106053116A (en) * | 2016-07-18 | 2016-10-26 | 合肥凯利光电科技有限公司 | Industrial detection method for anti-interference performance of alimentary canal power detector in low temperature environment |
| CN106178256A (en) * | 2016-07-08 | 2016-12-07 | 南京宽诚科技有限公司 | Intelligent gastrointestinal physical therapy device |
| CN108567423A (en) * | 2018-03-07 | 2018-09-25 | 南京宽诚科技有限公司 | A kind of detection method and device of bioelectrical signals |
| CN108577826A (en) * | 2018-03-07 | 2018-09-28 | 南京宽诚科技有限公司 | A kind of detecting system of stomach and intestine electric signal |
| CN108742590A (en) * | 2018-04-08 | 2018-11-06 | 南京宽诚科技有限公司 | A kind of acquisition method, device, collecting device and the storage medium of stomach and intestine electric signal |
-
2003
- 2003-09-29 CN CN 03135035 patent/CN1233297C/en not_active Expired - Fee Related
Cited By (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101961238A (en) * | 2010-10-09 | 2011-02-02 | 王光强 | Peristalsis monitor |
| CN105617530A (en) * | 2016-03-02 | 2016-06-01 | 西安交通大学第一附属医院 | Digital gastrointestinal pacemaker |
| CN106178256A (en) * | 2016-07-08 | 2016-12-07 | 南京宽诚科技有限公司 | Intelligent gastrointestinal physical therapy device |
| CN106178256B (en) * | 2016-07-08 | 2019-01-25 | 南京宽诚科技有限公司 | Intelligent stomach and intestine physical therapy device |
| CN106053116A (en) * | 2016-07-18 | 2016-10-26 | 合肥凯利光电科技有限公司 | Industrial detection method for anti-interference performance of alimentary canal power detector in low temperature environment |
| CN106053116B (en) * | 2016-07-18 | 2018-10-23 | 合肥凯利光电科技有限公司 | The industrial detection method of interference free performance in digestive tract power detector low temperature environment |
| CN108567423A (en) * | 2018-03-07 | 2018-09-25 | 南京宽诚科技有限公司 | A kind of detection method and device of bioelectrical signals |
| CN108577826A (en) * | 2018-03-07 | 2018-09-28 | 南京宽诚科技有限公司 | A kind of detecting system of stomach and intestine electric signal |
| CN108742590A (en) * | 2018-04-08 | 2018-11-06 | 南京宽诚科技有限公司 | A kind of acquisition method, device, collecting device and the storage medium of stomach and intestine electric signal |
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| Publication number | Publication date |
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| CN1233297C (en) | 2005-12-28 |
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Granted publication date: 20051228 Termination date: 20100929 |