CN1508112A - Process for producing 3,4-dihydroxy benzaldehyde - Google Patents
Process for producing 3,4-dihydroxy benzaldehyde Download PDFInfo
- Publication number
- CN1508112A CN1508112A CNA021582033A CN02158203A CN1508112A CN 1508112 A CN1508112 A CN 1508112A CN A021582033 A CNA021582033 A CN A021582033A CN 02158203 A CN02158203 A CN 02158203A CN 1508112 A CN1508112 A CN 1508112A
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- China
- Prior art keywords
- acid
- dihydroxy benzaldehyde
- production technique
- raw material
- pyrocatechol
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- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
The production process of 3,4-dihydroxybenzaldehyde is characterized by that it makes catechol and glyoxalic acid implement condensation reaction under the action of alkaline substance sodium hydroxide to produce 3,4-dihydroxyamygdalic acid, then makes the obtained 3,4-dihydroxyamygdalic acid and compound copper salt implement oxidation reaction and decarboxylation reaction so as to obtain the invented 3,4-dihydroxybenzaldehyde.
Description
Technical field: the production technique that the present invention relates to the 3.4-Dihydroxy benzaldehyde that uses in synthetic, the preparation of a kind of medicine, healthcare product.
Background technology: the production technique of the 3.4-Dihydroxy benzaldehyde that arrives involved in the present invention does not have to find to have identical complete processing application according to the Searches of Patent Literature.By domestic and international information retrieval, find 24 pieces of akin patent and non-patent literatures altogether, general pertinent literature introduced 3.4-Dihydroxy benzaldehyde, 2.4-Dihydroxy benzaldehyde, 2.3-Dihydroxy benzaldehyde in medicine, chemical field application and be raw material system 2.4-Dihydroxy benzaldehyde with the Resorcinol.
Summary of the invention: involved in the present invention to the 3.4-Dihydroxy benzaldehyde be a kind of intermediate, be applied to medicine, field of new, be to be raw material with the pyrocatechol, make finished product through chemical reactions such as condensation, oxidation, decarboxylations, it is characterized in that: pyrocatechol and oxoethanoic acid are carried out condensation reaction generation 3.4-dihydroxyl amygdalic acid under the effect of alkaline matter sodium hydroxide.The 3.4-dihydroxyl amygdalic acid and the compound mantoquita that generate are carried out oxidation, and decarboxylic reaction has generated the 3.4-Dihydroxy benzaldehyde and carbonic acid gas adds water.The main content of this product is 98.5%, and molten some 152-156 ℃, molecular formula is C
7H
6O
3Molecular weight is 138.0, and outer appearnce white or white crystalline powder are soluble in common organic solvents, be dissolved in hot water, have no irritating odor, belong to non-inflammable, explosive, hypertoxic product, starting raw material pyrocatechol and oxoethanoic acid that this production technique has adopted market to be easy to get, low processing cost, production technique has adopted quantitative analysis method to carry out follow-up control, guarantees high yield, low three waste discharge.
Embodiment: the present invention adopts pyrocatechol and oxoethanoic acid to make raw material, and pyrocatechol and oxoethanoic acid are carried out condensation reaction generation 3.4-dihydroxyl amygdalic acid under the effect of alkaline matter sodium hydroxide.
(pyrocatechol) (oxoethanoic acid) (3,4-dihydroxyl amygdalic acid)
The 3.4-dihydroxyl amygdalic acid and the compound mantoquita that generate are carried out oxidation, and decarboxylic reaction has generated the 3.4-Dihydroxy benzaldehyde and carbonic acid gas adds water.
(3,4-dihydroxyl amygdalic acid) (compound mantoquita) (3, the 4-Dihydroxy benzaldehyde)
Claims (1)
- Involved in the present invention to the 3.4-Dihydroxy benzaldehyde be a kind of intermediate, be applied to medicine, field of new, it is to be raw material with pyrocatechol and oxoethanoic acid, makes through chemical reactions such as condensation, oxidation, decarboxylations to form.The starting raw material that this production technique has adopted market to be easy to get, low processing cost, production technique has adopted quantitative analysis method, guarantees the high yield of product and to the low three waste discharge of environment protection.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNA021582033A CN1508112A (en) | 2002-12-20 | 2002-12-20 | Process for producing 3,4-dihydroxy benzaldehyde |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNA021582033A CN1508112A (en) | 2002-12-20 | 2002-12-20 | Process for producing 3,4-dihydroxy benzaldehyde |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN1508112A true CN1508112A (en) | 2004-06-30 |
Family
ID=34236912
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNA021582033A Pending CN1508112A (en) | 2002-12-20 | 2002-12-20 | Process for producing 3,4-dihydroxy benzaldehyde |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN1508112A (en) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101898957A (en) * | 2009-05-27 | 2010-12-01 | 中国石油天然气股份有限公司 | Method for synthesizing 3, 4-dihydroxyl mandelic acid by glyoxylic acid method |
| CN101531577B (en) * | 2009-04-08 | 2012-05-23 | 江苏食品职业技术学院 | A method for preparing 3, 4-dihydroxy benzaldehyde in ionic liquid with one-pot method |
| CN103012091A (en) * | 2011-09-22 | 2013-04-03 | 中国石油天然气股份有限公司 | Method for preparing 3,4-dihydroxy benzaldehyde through copper oxide lattice oxygen oxidation |
-
2002
- 2002-12-20 CN CNA021582033A patent/CN1508112A/en active Pending
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101531577B (en) * | 2009-04-08 | 2012-05-23 | 江苏食品职业技术学院 | A method for preparing 3, 4-dihydroxy benzaldehyde in ionic liquid with one-pot method |
| CN101898957A (en) * | 2009-05-27 | 2010-12-01 | 中国石油天然气股份有限公司 | Method for synthesizing 3, 4-dihydroxyl mandelic acid by glyoxylic acid method |
| CN103012091A (en) * | 2011-09-22 | 2013-04-03 | 中国石油天然气股份有限公司 | Method for preparing 3,4-dihydroxy benzaldehyde through copper oxide lattice oxygen oxidation |
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| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C02 | Deemed withdrawal of patent application after publication (patent law 2001) | ||
| WD01 | Invention patent application deemed withdrawn after publication |