CN1504738A - Optical system of multiple wavelength semi-automatic biochemistry analyzer - Google Patents

Optical system of multiple wavelength semi-automatic biochemistry analyzer Download PDF

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Publication number
CN1504738A
CN1504738A CNA021446423A CN02144642A CN1504738A CN 1504738 A CN1504738 A CN 1504738A CN A021446423 A CNA021446423 A CN A021446423A CN 02144642 A CN02144642 A CN 02144642A CN 1504738 A CN1504738 A CN 1504738A
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China
Prior art keywords
flat field
holographic grating
mirror
optical system
concave surface
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Pending
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CNA021446423A
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Chinese (zh)
Inventor
唐玉国
马海涛
陈今涌
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Changchun Institute of Optics Fine Mechanics and Physics of CAS
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Changchun Institute of Optics Fine Mechanics and Physics of CAS
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Application filed by Changchun Institute of Optics Fine Mechanics and Physics of CAS filed Critical Changchun Institute of Optics Fine Mechanics and Physics of CAS
Priority to CNA021446423A priority Critical patent/CN1504738A/en
Publication of CN1504738A publication Critical patent/CN1504738A/en
Pending legal-status Critical Current

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  • Spectrometry And Color Measurement (AREA)

Abstract

The invention relates to an improvement for the optical system of light filter type or optical grating type semi-automatic biochemical analyzer, which comprises a light source, a collimating mirror, a color matching disc, a focusing mirror, an entrance slit, an angle mirror, an array detector and a concave flat field holographic grating, wherein the concave flat field holographic grating and array detector eliminates the wave length repetitive error and save the switching over device of the light filter or the mechanical structure of the raster scanning, thus realizing simplified structure, improved analyzing speed and increased stability and reliability.

Description

A kind of optical system of multi-wavelength semi-automatic biochemical analyzer
Technical field: the invention belongs to semi-automatic biochemical analyzer, relate to improvement to optical filtering chip and raster pattern semi-automatic biochemical analyzer optical system.
Background technology: semi-automatic biochemical analyzer is a kind of hospital clinical conventional analysis instrument, its principle is based on the photoelectric colorimetry of Lambert-Beer's law, therefore for semi-automatic biochemical analyzer, its core is a spectrophotometer, and its performance directly has influence on the structure and the performance index of whole instrument.
At present in the world and the home market multiple model, two kinds of versions are arranged, a kind of is the optical filtering chip, a kind of is raster pattern.The structure of optical filtering chip comprises light source 1 as shown in Figure 1, colimated light system 2, optical filter 3, focusing system 4, detector 5.For the single-wavelength working situation, optical filter can fixed form, but owing to use single wavelength, the quantity of analysis project is restricted, if the use multi-wavelength then needs the switching mechanism of optical filter, it is complicated that the mechanism of instrument becomes, influence reliability, stableness of filter is the key that influences instrument complete machine performance at present in addition.The raster pattern structure as shown in Figure 2, comprise light source 2-1, colimated light system 2-2, monochromator 2-3, focusing system 2-4, detector 2-5, the raster pattern semi-automatic biochemical analyzer all adopts scan mode, its weak point is: the one, and raster scanning needs the regular hour, have the wavelength repetitive error simultaneously, the 2nd, instrument must have raster scanning mechanism.
Detailed content of the present invention: the objective of the invention is to solve background technology make sweep time the instrument travelling speed slow, have wavelength repetitive error, an apparatus structure complexity, problem such as stability and poor reliability, for this reason, the present invention will provide a kind of optical system that multi-wavelength semi-automatic biochemical analyzer uses that is suitable for.
Of the present invention comprising: light source, collimating mirror, cuvette, focus lamp, entrance slit, angle mirror, detector array, concave surface flat field holographic grating, on optical system coaxial, place light source, collimating mirror, cuvette, focus lamp, entrance slit, angle mirror, concave surface flat field holographic grating, detector array successively, the incident angle of the workplace of angle mirror and concave surface flat field holographic grating has a certain degree, the face of accepting of detector array and concave surface flat field holographic grating surperficial staggered relatively.
When the present invention worked: radiation of light source was behind the collimating mirror collimation, pass through cuvette, light by absorption of sample in the cuvette after, emergent light is focused on the entrance slit by focus lamp, by inciding concave surface flat field holographic grating after the angle mirror reflection, form flat field spectrum through the chromatic dispersion of concave surface flat field holographic grating, survey flat field spectrum by detector array at last.
Good effect of the present invention: the present invention adopts concave surface flat field holographic grating and detector array to eliminate the wavelength repetitive error, saved the physical construction of the switching mechanism or the raster scanning of optical filter, make it simple in structure, adopt detector array can finish the data test of a plurality of wavelength simultaneously, improved analysis speed, stability and reliability are improved, and ratio of performance to price height has broad application prospects.Solved background technology make sweep time the instrument travelling speed slow, have wavelength repetitive error, an apparatus structure complexity, problem such as stability and poor reliability, for this reason, the invention provides a kind of various biochemical indicators of measuring in people's body fluid that are mainly used in, comprise the optical system of the multi-wavelength semi-automatic biochemical analyzer of routine biochemistry indexs such as routine blood test, myocardial enzymes, blood pressure and blood lipoid, liver function, kidney merit, immunoglobulin (Ig).
Description of drawings:
Fig. 1 is the structural representation of background technology
Fig. 2 is the structural representation of background technology
Fig. 3 is a structural representation of the present invention
Embodiment: as shown in Figure 3: on base plate, be fixed with light source 3-1, collimating mirror 3-2, cuvette 3-3, focus lamp 3-4, entrance slit 3-5, angle mirror 3-6, detector array 3-7, grating 3-8 by support.
Light source 3-1 requires to select according to wavelength, and present embodiment can adopt quartz tungsten halogen lamp.Collimating mirror 3-2 can adopt quartz material to make lens.But cuvette 3-3 adopting quartz glass is made.Focus lamp 3-4 adopts quartz material to make lens.Entrance slit 3-5 adopts mechanical edge of a knife slit.Angle mirror 3-6 adopts the k9 optical glass material to make.
According in the practical application to the requirement of wavelength, determine the line element number of detector array 3-7, detector 3-7 adopts silicon (Si) photodiode array.Semi-automatic biochemical analyzer for six wavelength: 340nm, 405nm, 510nm, 546nm, 578nm, 630nm, grating 3-8 adopts concave surface flat field holographic grating, grating 3-8 linear dispersion is 15nm/mm, detector 3-7 line element number is chosen as six, and detector 3-7 spacing also can be chosen as d1=4.33mm, d2=7mm, d3=4.33mm, d4=2.4mm, d5=4.33mm, d5=2.13mm, d6=3.47mm successively.If spectral bandwidth is 6nm, then detector width is chosen as 0.4mm.The workplace of angle mirror 3-6 and optical axis have certain angle, the size of angle is determined according to the desired incident angle of concave surface flat field holographic grating 3-8, the face of accepting of detector array 3-7 and concave surface flat field holographic grating 3-8's is surperficial staggered relatively, so that receive the spectrum that is produced by concave surface flat field holographic grating 3-8.

Claims (1)

1, a kind of optical system of multi-wavelength semi-automatic biochemical analyzer, comprise light source 3-1, collimating mirror 3-2, cuvette 3-3, focus lamp 3-4, entrance slit 3-5, angle mirror 3-6, it is characterized in that: also include detector array 3-7, concave surface flat field holographic grating 3-8, on optical system coaxial, place light source 3-1 successively, collimating mirror 3-2, cuvette 3-3, focus lamp 3-4, entrance slit 3-5, angle mirror 3-6, concave surface flat field holographic grating 3-8, detector array 3-7, the incident angle of the workplace of angle mirror 3-6 and concave surface flat field holographic grating 3-8 has a certain degree, and the face of accepting of detector array 3-7 and concave surface flat field holographic grating 3-8's is surperficial staggered relatively.
CNA021446423A 2002-11-29 2002-11-29 Optical system of multiple wavelength semi-automatic biochemistry analyzer Pending CN1504738A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CNA021446423A CN1504738A (en) 2002-11-29 2002-11-29 Optical system of multiple wavelength semi-automatic biochemistry analyzer

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CNA021446423A CN1504738A (en) 2002-11-29 2002-11-29 Optical system of multiple wavelength semi-automatic biochemistry analyzer

Publications (1)

Publication Number Publication Date
CN1504738A true CN1504738A (en) 2004-06-16

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CNA021446423A Pending CN1504738A (en) 2002-11-29 2002-11-29 Optical system of multiple wavelength semi-automatic biochemistry analyzer

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CN (1) CN1504738A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN100454001C (en) * 2005-12-21 2009-01-21 沈阳东软医疗系统有限公司 Optical system of spectrophotometer of full-automatic biochemical analyzer

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN100454001C (en) * 2005-12-21 2009-01-21 沈阳东软医疗系统有限公司 Optical system of spectrophotometer of full-automatic biochemical analyzer

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