CN1493709A - Biofunction gradient composite coating layer material - Google Patents
Biofunction gradient composite coating layer material Download PDFInfo
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- CN1493709A CN1493709A CNA021461147A CN02146114A CN1493709A CN 1493709 A CN1493709 A CN 1493709A CN A021461147 A CNA021461147 A CN A021461147A CN 02146114 A CN02146114 A CN 02146114A CN 1493709 A CN1493709 A CN 1493709A
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Abstract
A composite coated material with biologic function gradient and proper porosity for adsorbing body fluid to induce it to become bone is prepared through using plasma spray method to spray 4 metallic layers on the surface of metal (Ti or CoCrMo alloy plate) in such manner that 4 layers have different porosities (the bottom layer is a compact layer), and spraying biologic HA layers with different porosities in order to allow the HA to penetrate in each layer to form a biologic function gradient and increase the bonding strength. Its advantages are high biologic compatibility and good bonding to bone.
Description
(1) technical field: the invention belongs to medical material tech field, particularly biological function gradient composite coating material.
(2) background technology: plasma spraying biological ceramics HA layer is applied at aspects such as artificial hip joints, although application is arranged both at home and abroad in this respect, bonding strength is not enough, does not still reach requirement.Spraying HA is divided into two aspects on Ti (or alloy) surface both at home and abroad: the one, directly at Ti alloy surface spraying HA, its shortcoming is that the bonding strength on coating and Ti surface is low, coating life is short and obscission arranged, improved again afterwards and added the metal Ti coating, spray HA again, though bonding strength increases, but still the problem that exists the HA layer to come off sometimes.The present invention adopts the biological function gradient composite coating to solve these problems.
(3) summary of the invention: the present invention has set about designing the functionally gradient compound coating from physics and biocompatibility aspect and has been coated with Ti (or Mo) coating of four layers of different aperture earlier in Ti (or CoCrMo alloy) alloy surface, solved physics by densification to the Gradient distribution of hole, mechanical compatibility, and provide porous surface for spraying outer HA layer, when spraying the HA layer again, HA has entered Ti (or Mo) layer hole, bonding strength just improves greatly like this, the HA tight zone plays and prevents the direct and metallic contact of body fluid in addition, improved the life-span of coating, outermost spraying porous HA and β-TCP composite diphase material are on the HA coating, its objective is both to have solved between HA and (the HA+ β-TCP layer) and combine problem, make its physical compatibility good, can make hole and β-TCP degraded new bone of growing into again, so just improve the bonding strength of coating and substrate surface, strengthened biocompatibility.This structure design of six layers has solved the technical barrier that individual layer or duplex coating can't resolve substantially.
Below engage accompanying drawing technical scheme is described in detail in detail
(1.Ti or CoCrMo) plate surface treatment:
Ti plate (or CoCrMo plate) is with 46
#Buddha's warrior attendant sand (Al
2O
3) processing of sandblasting, make surface irregularity, and remove scalping, clean with acetone then, make the coating after the spraying reach good bonding strength.
2. the plasma spraying condition is prepared:
Utilize vacuum plasma spray coating equipment, spray gun can be controlled (as the A-3000 plasma spraying machine of Sweden, its mechanical manipulator is the IRB-6 type of ABB AB) automatically in vacuum chamber, be sprayed under the 0.133Pa vacuum and charge into Ar, sprays.Spray gun is apart from sample 300mm, and the spraying sample is used plasma body preheating 3 ~ 4 minutes, and making the temperature of spray coating plate is 300 ~ 500 ℃, uses Ar
+Plasma sputtering cleaned 3 ~ 4 minutes.Under 10Pa Ar air pressure, be 60 ~ 70V generally, spray with 600 ~ 700A electric current and voltage.
3. the spraying of metal function gradient cladding:
By above-mentioned spraying condition metallize functionally gradient coating.Coating amounts to four layers, the metallisation of usefulness (Ti powder or Mo powder) granularity difference, and first floor coating thickness is 25 μ m, each layer thickness is 50 μ m thereafter.Spraying current is controlled at 600 ~ 700A.
The first layer is a tight zone, is 300 orders with metal powder (Ti or Mo powder) granularity, and coating thickness is 25 μ m;
The second layer is 50 μ m with 250 order metal powders (Ti or Mo powder) coating thickness, and its porosity is 10 ~ 50 μ m;
The 3rd layer of usefulness 150 order metal powder (Ti or Mo powder) coating thickness is 50 μ m, and its porosity is 50 ~ 100 μ m;
The 4th layer of usefulness 50 order metal powder (Ti or Mo powder) coating thickness is 50 μ m, and its porosity is 100 ~ 300 μ m.
4. the spraying of biological function gradient cladding (the 5th, six layer):
The biological function coating is two-layer, respectively with HA and (HA+ β-TCP) the coating spraying electric current is 600 ~ 650A.
Wherein the first biomaterial coating (layer 5) sprays fine and close HA with 300 purpose HA powder, and thickness is 25 μ m, makes it to reach HA and infiltrates the metal hole, has sealed the purpose of body fluid infiltration metallic coating again.Outermost layer each complex phase powder of 50% of HA+ β-TCP, granularity is 60 orders, and spraying current is 600A, and coating thickness is 50 μ m, and pore diameter is about 50 ~ 200 μ m, and it is suitable for adsorbing body fluid and helps β-TCP degraded and induced osteogenesis, makes biocompatibility better.
Beneficial effect of the present invention: physical compatibility is good, the bonding strength height, and good biocompatibility has the good surface bioactive and the function of induced osteogenesis.
(4) description of drawings: Fig. 1 is a coated material structure iron of the present invention.
Fig. 2 is a coated material manufacturing approach craft schema of the present invention.
(5) embodiment:
Example 1:
The titanium plate is 30mm * 20mm * 2mm, with 46
#Buddha's warrior attendant sand (Al
2O
3) sandblast and handled 4 minutes, make the surface become bright, remove scalping, put into the plasma body vacuum chamber then, be evacuated down to 0.133Pa, fill Ar then.Spray gun is apart from sample (titanium plate) 300mm, and plasma body preheating titanium plate 4 minutes reaches about 400 ℃, Ar
+Plasma sputtering cleaned 4 minutes, then at Ar+H
2Behind the air pressure 10Pa, sending into the titanium valve of 300 order granularities by powder feeder, is 60V at voltage, under the electric current 600A, sprays, and reaches 25 μ m thickness.The second layer changes sends into 250 order Ti powder, and voltage is constant, is sprayed into 50 μ m thickness with the 620A electric current.The 3rd layer of usefulness 150 purpose Ti powder spray to 50 μ m thickness under 640A.The 4th layer of usefulness 60 purpose Ti powder are sprayed onto 50 μ m under 650A.Spraying the HA layer then, is 600A with sending into 300 purpose HA powder spraying currents, and being sprayed onto thickness is 25 μ m, changes then and sends into 60 purpose HA+ β-TCP powder, sprays to 50 μ m under 610A.Continuous like this having finished at Ti surface sprayed biological functionally gradient composite bed.
Example 2:
The Mo plate is 30mm * 20mm * 2mm, with 46
#Buddha's warrior attendant sand (Al
2O
3) sandblast and handled 4 minutes, remove scalping, put into the plasma body vacuum chamber then, be evacuated down to 0.133Pa, fill Ar then, spray gun is apart from sample 300mm, and with plasma body preheating 3 minutes, the Mo plate reached about 400 ℃, Ar
+Plasma sputtering cleaned 3 minutes, then at Ar+H
2Under the air pressure 10Pa, sending into 300 order molybdenum powders by powder feeder, is 60V at voltage, under the electric current 600A, sprays to 25 μ m thickness.Send into 250 order molybdenum powders then under 610A, spray the coating of 50 μ m thickness, under 620A, spray 50 μ m coatings with 150 purpose molybdenum powders successively.Thereafter molybdenum coating is to send into 60 order molybdenum powders, under 630A, sprays the coating of 50 μ m.
Be the sprayed biological functionally gradient coating at last, at 60V, coating thickness is the HA tight zone of 25 μ m to the coating of close metal under the electric current 600A with 300 purpose HA grains.Under 610A, send into HA+ β-TCP (each 50%) powder again and spray the thick bioactive coating of 50 μ m.
Claims (7)
1. biological function gradient composite coating material is a lamination layer structure, it is characterized in that it is made up of four layers of metal function gradient cladding and two layers of biological function gradient cladding and Ti or Ti metal sheet, apply the metallic coating of four layers of different aperture successively on Ti or Ti metal plate surface, four layers of metallic coating apply two layers of bioactive functions calcium orthophosphate base coating outward again.
2. biological function gradient composite coating material as claimed in claim 1 is characterized in that described four layers of metallic coating are Ti powder or Mo powder, and the thick coating that its first floor promptly directly is coated on the Ti plate is 25m, and all the other threeplies are 50m.
3. biological function gradient composite coating material as claimed in claim 1 is characterized in that the described first floor is the close layer of making a speech, and the second layer is the aperture layer, and the 3rd layer is mesoporous layer, and the 4th layer is macroporous layer.
4. biological function gradient composite coating material as claimed in claim 1 is characterized in that described bioactive functions calcium orthophosphate base coat-thickness is 75m, internal layer HA powder, outer with 50%HA and-the TCP powder mix.
5. the manufacture method of biological function gradient composite coating material is characterized in that by following flow process:
(1) Ti alloy sheets surface treatment
(2) the plasma spraying condition is prepared
(3) metallize functionally gradient coating
(4) sprayed biological functional coating HA layer
(5) sprayed biological functional coating HA+ β-TCP layer
6. the manufacture method of biological function gradient composite coating material as claimed in claim 5 is characterized in that the Ti plate with the husky processing of Buddha's warrior attendant sand blasting, cleans with acetone again.
7. the manufacture method of biological function gradient composite coating material as claimed in claim 5 is characterized in that selecting for use vacuum plasma spray coating equipment, and is to carry out under the 0.133Pa in vacuum tightness.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNA021461147A CN1493709A (en) | 2002-10-31 | 2002-10-31 | Biofunction gradient composite coating layer material |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNA021461147A CN1493709A (en) | 2002-10-31 | 2002-10-31 | Biofunction gradient composite coating layer material |
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| Publication Number | Publication Date |
|---|---|
| CN1493709A true CN1493709A (en) | 2004-05-05 |
Family
ID=34232634
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNA021461147A Pending CN1493709A (en) | 2002-10-31 | 2002-10-31 | Biofunction gradient composite coating layer material |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103526196A (en) * | 2013-10-23 | 2014-01-22 | 中国科学院上海硅酸盐研究所 | Method for preparing Ti coating hard tissue alternate material with hierarchical structure |
| CN104644289A (en) * | 2015-03-24 | 2015-05-27 | 国家康复辅具研究中心 | Method for preparing artificial bone prosthesis with dual gaps |
| CN111921011A (en) * | 2020-09-08 | 2020-11-13 | 西安点云生物科技有限公司 | Artificial bone coated with coating and preparation method thereof |
-
2002
- 2002-10-31 CN CNA021461147A patent/CN1493709A/en active Pending
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103526196A (en) * | 2013-10-23 | 2014-01-22 | 中国科学院上海硅酸盐研究所 | Method for preparing Ti coating hard tissue alternate material with hierarchical structure |
| CN104644289A (en) * | 2015-03-24 | 2015-05-27 | 国家康复辅具研究中心 | Method for preparing artificial bone prosthesis with dual gaps |
| CN111921011A (en) * | 2020-09-08 | 2020-11-13 | 西安点云生物科技有限公司 | Artificial bone coated with coating and preparation method thereof |
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