CN1484184B - Method and system for traditional Chinese medicine flexibilized electronic prescription - Google Patents
Method and system for traditional Chinese medicine flexibilized electronic prescription Download PDFInfo
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Abstract
The method and system of Chinese traditional medicine flexibility electron formula, the character lies in: A. it separates Chinese traditional medicine and extracts effective component through using the heterogeneity multi-matter synchronization separation technology and other modern Chinese traditional medicine extraction technology; B. establishes the spectrum effect union Chinese traditional medicine effective component quality and the data bank through the pharmacodynamics experiment and the Chinese traditional medicine effective component extraction fingerprint atlas; C. produces the extracted material into standard quota Chinese traditional medicine particles through modern particle producing technology. D. puts the Chinese traditional medicine particles in the modular particle storage system, counts and quantifies the particle through control valve which is controlled by computer and photo-electricity gauge system; E. carries on the collection of medicine through the robot collection or conveyer belt.
Description
Technical field: the method and system that the present invention relates to Chinese medicine flexibility electron formula.
Background technology:
Chinese medicine is treated both principal and secondary aspect of disease because of having, and the advantage that toxic and side effect is little enjoys patient's favor over the past thousands of years.Along with the development and the development of technology of modern science and technology, the especially breakthrough of modern Chinese herbal medicine extractive technique, the application mode of Chinese medicine also faces change.Based on:
Shortcomings such as 1) active constituent content of traditional Chinese medicine is low, and quantitatively inaccurate, sanitary condition is poor, decocts inconvenience, and dosage is big also manifest day by day.
2) the artificial prescription of tradition labour intensity height, inefficiency.
3) traditional Chinese patent drug is fixing because of filling a prescription, and makes it to lose fully the dialectical opinion of Chinese medicine and controls, with the feature of disease plus-minus.
Summary of the invention;
But the object of the present invention is to provide a kind of modern Chinese herbal medicine extractive technique of set suitability for industrialized production, the method for the Chinese medicine flexibility electron formula of Computer Control Technology and Traditional Chinese medical theory.
Another object of the present invention is to provide a kind of system of Chinese medicine flexibility electron formula.
Technical characterictic:
The method of Chinese medicine flexibility electron formula is characterized in that: A, by adopting heterogeneous many materials separated in synchronization technology and other modern Chinese herbal medicine extractive technique, separating traditional Chinese medicine, effective component extracting; B, the finger-print by pharmacodynamic experiment and Chinese medicine effective component extracts are set up middle pharmaceutically active ingredient quality standard and database that spectrum is imitated combination; C, utilize modern particulate manufacturing technology, Chinese medical extract is made into standardized, quantitative Chinese medicine particulate; D, the Chinese medicine particulate is placed in the modularization particulate stocking system, the Chinese medicine particulate is counted and quantitatively by computer-controlled operation valve 2 and photoelectric metering system; E collects medicine by collection medicine system of robot or travelling belt to prescription Chinese medicine; D, finish according to prescription by computing machine after the quantity and the volume of particulate, add auxiliary material automatically and be made into capsule, tablet or oral liquid.
The method of Chinese medicine flexibility electron formula is characterized in that:
(1), by adopting heterogeneous multi-solvent separated in synchronization technology and other modern Chinese herbal medicine extractive technique, separating traditional Chinese medicine, effective component extracting;
(2), the finger-print by pharmacodynamic experiment and Chinese medicine effective component extracts, set up middle pharmaceutically active ingredient quality standard and database that spectrum is imitated combination;
(3), utilize modern particulate manufacturing technology, Chinese medical extract is made into standardized, quantitative Chinese medicine particulate;
(4), according to the reduction coefficient of actual Chinese medicine and extract, determine Chinese medicine content of effective in every particulate; In computing machine, set up Chinese medicine active constituent content database in each flavor Chinese medicine particulate; Also set up middle pharmaceutically active ingredient quality standard and the database that spectrum is imitated combination;
(5), every flavor Chinese medicine particulate is placed in the modularization particulate stocking system;
(6), by doctor or pharmacist will write out a prescription the input computing machine in;
(7), computing machine passes through pharmaceutically active ingredient database in the Chinese medicine particulate, the automatic granule number that every flavor Chinese medicine in the doctor formula is converted into standardized quantitative single medicinal material particulate;
(8), computer instruction operation valve 2 is open;
(9), the Chinese medicine particulate is by operation valve 2;
(10), the Chinese medicine particulate is by optoelectronic metering installation and be counted;
(11), the counting finish, computer instruction operation valve 2 is closed;
(12), the Chinese medicine particulate by counting enters collection medicine system or travelling belt prescription Chinese medicine collected medicine, sends into reducing mechanism;
(13), finish according to prescription by computing machine after the quantity and the volume of particulate, calculate kind and quantity that auxiliary material adds, instruction formulation system work and add auxiliary material;
(14), be made into capsule, tablet or oral liquid by the formulation system Chinese medicine of will filling a prescription.
The method of described Chinese medicine flexibility electron formula is characterized in that: computer system can be added selected side of traditional Chinese medicine and distinguished veteran doctors of TCM prescription system, realizes that tcm prescription is rapid.
Be described in detail as follows:
A, Chinese medicine is extracted, separates, make middle pharmaceutically active ingredient with heterogeneous multi-solvent separated in synchronization technology:
This technology relates to the big class material of 17 in the natural plants, and hundreds of extracts solvent; Can extract different materials simultaneously, have extraction efficiency height, characteristics with low cost; Because the extraction solvent types that adopts is many and the separated in synchronization technology, has the characteristics such as biologic activity height of extract purity height, extract, and can extract many material or the effective constituents that can't extract in present technical conditions; And set up Chinese medicine effective component extracts finger-print on this basis; With this collection of illustrative plates is standard, in conjunction with pharmacodynamic experiment, the quality of centering pharmaceutically active ingredient extract is controlled, no matter and the place of production of Chinese medicine itself, the source, extracting mode, content of effective and content of harmful, all can guarantee the unification of the Chinese medicine standardization particle mass that dispatches from the factory, and meet middle pharmaceutically active ingredient finger-print and national standard; Utilize modern particulate manufacturing technology, Chinese medical extract is made into standardized, quantitative particulate.
Because the broad applicability of this technology makes extensive industrialization traditional Chinese medicine extraction be separated into reality.
Pharmaceutically active ingredient quality standard (finger-print) and middle pharmaceutically active ingredient database open, that share carry out quality control to the Chinese medicine intermediate in B, the usefulness:
The Chinese medicine place of production, collection season, factors such as extracting method all are the key factors that influence Chinese medicine stability.The stability of Chinese medicine intermediate becomes the most important index of Chinese medicine.The pharmaceutically active ingredient finger-print carried out quality control during the approach of solution stability adopted exactly.Get rid of various factors, set up standard to be discerned and check in the terminal of Chinese medicine.
Domestic and international research mechanism and personnel have done big quantity research to the pharmaceutical characteristic and the effective constituent of Chinese medicine.But, cause its achievement in research not share because the method that adopts and raw material sources etc. are different.Pharmaceutically active ingredient finger-print in the employing in conjunction with the pharmacodynamic experiment result of different institutions, is set up an opening, shared middle pharmaceutically active ingredient database platform.The Chinese medical extract that is pharmaceutically active ingredient finger-print in all can meeting all can add this database platform, all can finally enter the preparation system of Chinese medicine flexibility electron formula system by the Chinese medicine intermediate of this standard production.
C, Computer Control Technology
Total system is based on computer-controlled automatization system, the folding of computer control Chinese medicine particulate operation valve 2 and the size and the speed of folding.The control accurate metering system, control robot collection medicine system or travelling belt, preparation and packaging system, middle pharmaceutically active ingredient storage location identification, the conversion between traditional Chinese medicine and the middle pharmaceutically active ingredient, valuation and pharmaceutical administration etc.
Advantage: characteristics of the present invention:
1) dialectical opinion is controlled, and with disease plus-minus, meets the traditional theory of traditional Chinese medical science of Traditional Chinese medical theory: theory of traditional Chinese medical science has fully proved its validity and security through real example in 1,100.Theory of traditional Chinese medical science is the core and the basis of treatment by Chinese herbs.The modernization of Chinese medicine can not be abandoned the traditional theory of the traditional Chinese medical science.Any disengaging differential diagnosis in tcm opinion is controlled and is all failed with the modernization of Chinese medicine scheme of disease plus-minus.Adopt modern extraction technique and preparation preparation techniques, in conjunction with the dialectical opinion of traditional Chinese medical science tradition control, with the theory of disease plus-minus and the wholistic therapy thought of the harmony between man and nature, the individualized treatment scheme of the complete reservation traditional Chinese medical science is the core concept that constitutes this method.
2) accurate measurement: the accuracy of Chinese medicine metering is the key factor that guarantees curative effect.One of drawback of traditional Chinese medicine is exactly that metering is inaccurate.Adopt light mechanical and electrical integration, the optical, mechanical and electronic integration control technology can be carried out accurate measurement to the Chinese medicine particulate of standard fabrication.
3) make up a prescription accurately.
4) easy to use, efficient is high.
5) total system all is in full closeding state, no cross pollution from operation valve below 2.
6) whole process meets the GMP standard.
The prospect that possesses the industrialization large-scale application: the research of the modernization of Chinese medicine will solve the process preparation problem of Chinese medicine exactly, the research of any processing and preparation all faces with the problem of what product form towards the patient, and this method provides solution for modernization of Chinese medicine final products form problem.
Technological core:
The method of Chinese medicine flexibility electron formula:
1) the quantitative single medicinal material effective constituent of standardization particulate.
2) pharmaceutically active ingredient finger-print and pharmacodynamic experiment combination in, middle pharmaceutically active ingredient database and quality standard that spectrum effect relationship is clear and definite.
3) flow process of total system.The computer control software of total system.
The system of Chinese medicine flexibility electron formula:
1) modularization Chinese medicine particulate hold-up vessel 1 and photoelectric metering system.
2) operation valve 2.
3) collection medicine system.
Description of drawings:
Fig. 1: the system construction drawing of Chinese medicine flexibility electron formula.
Fig. 2: the principle assumption diagram of modularization particulate stocking system and photoelectric metering system among Fig. 1.
Fig. 3: hold-up vessel structural drawing in the system equipment of Chinese medicine flexibility electron formula.
Fig. 4: equipment structure chart in the system of Chinese medicine flexibility electron formula.
Fig. 5: the CPU working routine process flow diagram of the control system of the system of Chinese medicine flexibility electron formula.
Fig. 6: the unit controls program flow diagram of the control system of the system of Chinese medicine flexibility electron formula.
Fig. 7: the hold-up vessel control program process flow diagram of the control system of the system of Chinese medicine flexibility electron formula.
Fig. 8: system's control chart of the system of Chinese medicine flexibility electron formula.
Fig. 9: the unit controls circuit of the control system of the system of Chinese medicine flexibility electron formula.
Figure 10: hold-up vessel 1 control circuit in the control system of the system of Chinese medicine flexibility electron formula.
Figure 11: the optoelectronic metering installation one-piece construction figure of the system of Chinese medicine flexibility electron formula.
Embodiment:
The method of Chinese medicine flexibility electron formula:
By adopting heterogeneous many materials separated in synchronization technology and other modern Chinese herbal medicine extractive technique, separating traditional Chinese medicine.In conjunction with in pharmaceutically active ingredient finger-print and pharmacodynamic experiment, pharmaceutically active ingredient quality standard and database in the foundation.Utilize modern particulate manufacturing technology, Chinese medical extract is made into standardized, quantitative particulate.Standardized quantitative single medicinal material particle.According to the reduction coefficient of actual Chinese medicine and extract, determine the content of Chinese medicine in every particulate, for final accurate quantification lays the foundation.The diameter design of particulate is at 50 μ m～2000 μ m.Diameter depends on the height of active constituent content in the Chinese medical extract and the measuring accuracy of photoelectric metering system.By optoelectronic metering installation particulate is counted, thereby Chinese medicine is carried out accurate quantification and prescription.The quantity and the volume of particulate after finishing according to prescription are added auxiliary material and are made into capsule, tablet and oral liquid by computer controlled automatic.
The system of Chinese medicine flexibility electron formula comprises: modularization particulate stocking system and photoelectric metering system.The particulate stocking system is designed to interchangeable hold-up vessel 1, and this tank body connects with operation valve 2 by the interface of a plane opening.Operation valve 2 is converted into steering order according to the prescription instruction that computing machine obtains, and control is by the particle number of operation valve 2.Operation valve 2 belows are optoelectronic metering installation 4, and this inductor measures the particulate by operation valve 2 according to computer instruction, and feed back to computing machine, are sent the folding time and the size of instruction control operation valve 2 by computing machine.Hold-up vessel 1, operation valve and photoelectric metering system will form a functional module.Each functional module is with a kind of Chinese medicine particulate of correspondence.Functional module can be assembled into a functional module collection according to user's demand.
The system of Chinese medicine flexibility electron formula constitutes:
1) preparation system
The single medicinal material particulate of pharmaceutically active ingredient finger-print during main preparation meets.This is an open platform, and the Chinese medicine production firm of pharmaceutically active ingredient finger-print and quality standard all can add this platform in all meeting.The Chinese medicine that native system mainly prepares based on heterogeneous multi-solvent separated in synchronization technology.Finish standardized, quantitative Chinese medicine particulate in factory.This particulate is the basis of measuring by the photoelectric metering system.
2) control system
By the input of computer program control doctor of traditional Chinese medicine prescription, identification, pharmaceutically active ingredient database in calling is by the operation valve 2 and the metering of photoelectric metering system of control Chinese medicine stocking system.Control collection medicine system or travelling belt Chinese medicine particulate and the auxiliary material potpourri of finishing of will filling a prescription is transported to preparation, packaging system and label printing system, finally pays the patient and uses.Whole process will not have artificial the intervention.
3) modularization single medicinal material stocking system and photoelectric metering system
See Fig. 2, this system is by single hold-up vessel 1, the functional module that operation valve 2 and optoelectronic metering installation 4 constitute, the corresponding a kind of Chinese medicine particulate of each module.This module can be combined into the stocking system of 500～2000 kinds of Chinese medicines according to demand.Hold-up vessel 1 hypomere is fixed on hold-up vessel 1 on the panel 7 by groove on the panel 5 and spherical plunger 6.The tight-lipped close interlock of jar of the operation valve 2 of lower end and hold-up vessel 1 is connected with the collection medicine system of operation valve 2 lower ends simultaneously, is travelling belt below.Operation valve 2 ends are optoelectronic metering installations.When computer instruction control operation valve 2 is opened, instruct optoelectronic metering installation to measure simultaneously, measure the computer instruction operation valve 2 that finishes and close.
4) collection medicine system of robot or travelling belt
Collection medicine system adopts robot or travelling belt collection medicine, and different types of Chinese medicine collection of particles that will be by each operation valve 2 also is transported to formulation system.
5) formulation system and packaging system (comprising label printing)
The Chinese medicine that formulation system is finished prescription is made into capsule, tablet and oral liquid.Computing machine will according to prescription and actual prescription finish the particle number of back Chinese medicine and estimate in capsule, tablet and the oral liquid quantity that will make, the addition of definite auxiliary material automatically.
The capsule number of single prescription design is 20～30, and capsule is divided into 250mg and two kinds of specifications of 500mg, orally also props up for 5ml～10ml/.
For guaranteeing patients ' interest, print system will print doctor formula, the Chinese medicine kind and the particle number of actual prescription, information such as instructions of taking and date.And write out a prescription and to revise once input validation.
See Fig. 4: equipment structure chart in the system of Chinese medicine flexibility electron formula.Be numbered among Fig. 4: system shell 12, hold-up vessel 1, chlorination equipment 13, drying device 14, collection medicine system 15, travelling belt 16, medicine 17, reducing mechanism 18, pharmaceutical device 19, support 20, motor 21.
Structure is: hold-up vessel 1 is installed on the panel 7, collection medicine system 15 is an infundibulate device, be installed in panel 7 bottoms, travelling belt 16 is installed in the lower part outlet place of collection medicine system 15, reducing mechanism 18, pharmaceutical device 19 are installed on the support 20, reducing mechanism 18 is connected with motor 21, and reducing mechanism 18 is connected and is installed in the outlet of collection medicine system 15 with pharmaceutical device 19, and the outlet of pharmaceutical device 19 is connected transmission medicine finished product 17 with medicine travelling belt on the support 20.Travelling belt 16 is installed in the lower part outlet place of collection medicine system 15, is used for transmitting the Chinese medicine fine-grained particles of collection medicine system 15, is applicable to the device that more hold-up vessel 1 is installed.
Hold-up vessel 1 structural drawing among Fig. 3.Be numbered among Fig. 3:
Top cover 31, charging aperture 32, dry slot 33, securing member 34, sealing gasket 35, operation valve 2, optoelectronic metering installation 4, light source 38, panel 7;
Structure is: hold-up vessel 1 is installed on panel 7, fixing with securing member 34, the outlet of hold-up vessel 1 has sealing gasket 35, the bottom of sealing gasket 35 is an operation valve 2, operation valve 2 lower ends pipe is outer to be light source 38 and optoelectronic metering installation 4, hold-up vessel 1 is suitable for reading to be charging aperture 32, fixing dry slot 33 around the charging aperture 32, and hold-up vessel 1 is suitable for reading to have top cover 31 to cover mouth.Panel 7 and securing member 34 stationary storage jars 1.
Hold-up vessel 1 principle: open top cover 31 during use, the Chinese medicine fine-grained particles in charging aperture 32 tank fillings, the size of the open and close of computer control operation valve 2 and switch folding.Light source 38 and optoelectronic metering installation 4 countings, count information sends control system to, by control system information is passed to computing machine.
See Fig. 5: the CPU working routine process flow diagram of the control system of the system of Chinese medicine flexibility electron formula.
Its feature comprises: the CPU working procedure flow process of the control system of the system of Chinese medicine flexibility electron formula comprises: beginning 1--system initialization (step 41), and--System self-test (step 42)--is judged System self-test by (step 43) if--pass through--to judge idle (step 44) if--be no,--converting and work out lower teletype command (step 45) in the log-on data storehouse,----starting the collection medicine device starts working (step 47)--waits for back information (step 48) and--judge each unit drug--send out the information of finishing dealing with (step 50) to counterpart terminal, and point out demonstration--the Stopping Sets medicine device of finishing (step 49) work (step 50) to send drug instruction (step 46) to correlation unit; When judge System self-test by (step 43) if--not passing through--reports to the police, shows that self check content and palpus manual intervention incident (step 52)--turn back to--System self-test (step 42); When judging idle (step 44) if----inquire about the next each location mode (step 53)--for being and judge that all location modes are good by the unit (step 54) is if--for being--return judgement " free time " (step 44); Judge all location modes good (step 54) if--for denying--return beginning 1;
See Fig. 6: the unit controls program flow diagram of the control system of the system of Chinese medicine flexibility electron formula.
Does its feature comprises: beginning 2--judge that this unit drug task is arranged? do be (step 61) if----send medicine and go out dose instruction (step 62) to corresponding photoelectric metering control circuit uP instruction control valve--judge that slave computer returns drug and finishes to be "Yes"? (step 63) is if--for being--judge that all drugs of this unit finish (step 64); If for not--return " judging that slave computer returns drug and finishes? " (step 63).--prepare report information (step 65) and--judge that host computer requires to report (step 66) if----report (step 67) by the host computer requirement--for being and prepare to report data (step 70) to host computer (CPU);
See Fig. 7: the hold-up vessel control program process flow diagram of the control system of the system of Chinese medicine flexibility electron formula.
be its feature comprises: is beginning 3--judgement beginning metering (step 71) if--yes--drug sum (step 72) and--judge an INT input pulse (step 73) if--be that "Yes"--down counter-1 (step 74)--is judged down counter=0? (step 75) is if----close solenoid valve (step 76)--for "Yes" and prepare report information (step 77), drug is finished.From beginning 3--judge begin metering (step 71) if--require report for no---judges host computer? (step 78) is if--being "Yes",--reporting (step 79) by the host computer requirement--prepares to report data (step 82).From judge " host computer requires to report? " (step 78) if--being "No"--judges " need report to host computer? " (step 80) is if--being "Yes",--reporting (step 81) to the host computer application--prepares to report data (step 82).
Fig. 8: system's control chart of the system of Chinese medicine flexibility electron formula.Fig. 8 is divided into three layers the superiors for total system.
Comprise: total system is divided into three layers, and the superiors are server, and server can connect many client computer/terminals by hub, supplies with the doctor and uses; Client computer/terminal 1A--nA connects a plurality of unit controls circuit MP by server, system master computer CPU connected system bus.
Client computer/terminal 1A--nA is by a plurality of unit controls circuit of server controls MP.
Fig. 9: the unit controls circuit of the control system of the system of Chinese medicine flexibility electron formula, Fig. 8 are divided into three layers the 2nd layer for total system.
Comprise: system bus linkage unit control circuit single trigger MP, single trigger MP connects a plurality of cellular system buses, and each cellular system bus connects a plurality of hold-up vessels.
Illustrate:
1, total system is divided into some unit, is connected with hold-up vessel by the cellular system bus, and each unit comprises 50 hold-up vessels (NO1--NO50), thereby the composition of system is flexibly.When needing more hold-up vessel, the unit of formation just at most.
3, corresponding, the control of each unit is relatively independent.
4, wherein unit controls circuit MP is a binding site between hold-up vessel control circuit and the main control computer.MP is by being sold general single trigger on the market.
Figure 10: hold-up vessel 1 control circuit in the control system of the system of Chinese medicine flexibility electron formula.Fig. 9 is divided into three layers the 3rd layer for total system.
Comprise FD light emitting source, phototriode T, phototriode T connects amplifying circuit, and amplifying circuit connects shaping circuit, and shaping circuit connects photoelectric metering control circuit uP, photoelectric metering control circuit uP linkage unit system control bus.
Illustrate:
1FD is a light emitting source, select luminotron for use, T is a phototriode, when having the Chinese medicine particulate to pass through in the metering conduit, the light intensity that phototriode T is received changes, the electric current of the pulsation of signals converted for counting with the number of light intensity (or with have or not Chinese medicine particulate by) corresponding pulse (or train of impulses) photoelectric metering control circuit uP paired pulses, is promptly finished the metering to throughput after amplifying shaping.
2, photoelectric metering control circuit uP implements the control to high-speed electromagnetic valve, receive the instruction of " drug " as photoelectric metering control circuit uP, and clear and definite " going out dose ", and the collection medicine device is when ready, be that control electromagnetic valve " is opened ", begin metering simultaneously,, promptly close solenoid valve rapidly when " going out dose " when reaching requirement.
Figure 11: the optoelectronic metering installation one-piece construction figure of the system of Chinese medicine flexibility electron formula.
Light emitting diode FD, solenoid valve DF are installed on the conduit 40, and photoelectric metering control circuit uP connects solenoid valve DF, and photoelectric metering control circuit uP is connected to system bus.
Illustrate:
1, light emitting diode FD is the light source of whole metering system.
2, solenoid valve DF accepts the control (ON/OFF) of unit controls circuit
3, photoelectric metering control circuit uP is a whole set of circuit, realizes the control unit circuit of the bottom of distributed control as total system.
4, above-mentioned three parts are installed attached on the conduit 40, each corresponding unit of flavor Chinese medicine.
Claims (5)
1. the method for Chinese medicine flexibility electron formula is characterized in that:
(1), by adopting heterogeneous multi-solvent separated in synchronization technology and other modern Chinese herbal medicine extractive technique, separating traditional Chinese medicine, effective component extracting;
(2), the finger-print by pharmacodynamic experiment and Chinese medicine effective component extracts, set up middle pharmaceutically active ingredient quality standard and database that spectrum is imitated combination;
(3), utilize modern particulate manufacturing technology, Chinese medical extract is made into standardized, quantitative Chinese medicine particulate;
(4), according to the reduction coefficient of actual Chinese medicine and extract, determine Chinese medicine content of effective in every particulate; In computing machine, set up Chinese medicine active constituent content database in each flavor Chinese medicine particulate;
(5), every flavor Chinese medicine particulate is placed in the modularization particulate stocking system;
(6), by doctor or pharmacist will write out a prescription the input computing machine in;
(7), computing machine passes through pharmaceutically active ingredient database in the Chinese medicine particulate, the automatic granule number that every flavor Chinese medicine in the doctor formula is converted into standardized quantitative single medicinal material particulate;
(8), operation valve (2) is open in the computer instruction modularization particulate stocking system;
(9), the Chinese medicine particulate is by operation valve (2);
(10), the Chinese medicine particulate is by optoelectronic metering installation and be counted;
(11), the counting finish, computer instruction operation valve (2) is closed;
(12), the Chinese medicine particulate by counting enters collection medicine system or travelling belt prescription Chinese medicine collected medicine, sends into reducing mechanism;
(13), finish according to prescription by computing machine after the quantity and the volume of particulate, calculate kind and quantity that auxiliary material adds, instruction formulation system work and add auxiliary material.
(14), be made into capsule, tablet or oral liquid by the formulation system Chinese medicine of will filling a prescription.
2. the method for Chinese medicine flexibility electron formula according to claim 1 is characterized in that: computer system can be added selected side of traditional Chinese medicine and distinguished veteran doctors of TCM prescription system, is selected by doctor or pharmacist, realizes the rapid making Chinese medicine of tcm prescription patent medicine.
3. the system of Chinese medicine flexibility electron formula comprises charging system, formulation system, packaging system, control system,
It is characterized in that comprising: modularization particulate stocking system connects photoelectric metering system and collection medicine system of robot or travelling belt, connects formulation system and packaging system again; Control system is connection mode blocking particulate stocking system, photoelectric metering system, collection medicine system of robot or travelling belt, formulation system and packaging system respectively;
Modularization particulate stocking system is interchangeable hold-up vessel (1), and hold-up vessel (1) connects with operation valve (2) by the interface of a plane opening; Operation valve (2) is connected with computer control main frame (3), according to the particle number of computer instruction control by operation valve (2); Operation valve (2) below is the optoelectronic metering installation (4) of photoelectric metering system, this optoelectronic metering installation (4) is connected with computer control main frame (3), according to computer instruction the particulate by operation valve (2) is measured, and after feeding back to computing machine, send instruction by computing machine and make operation valve (2) open or close; Hold-up vessel (1), operation valve (2) and photoelectric metering system form a functional module; Each functional module is with a kind of Chinese medicine particulate of correspondence; A plurality of functional modules are assembled into a functional module collection according to user's demand;
Hold-up vessel (1) is installed on the panel (7), collection medicine system (15) is an infundibulate device, be installed in panel (7) bottom, travelling belt (16) is installed in the lower part outlet place of collection medicine system (15), support (20) is gone up reducing mechanism (18), pharmaceutical device (19) is installed, reducing mechanism (18) is connected with motor (21), reducing mechanism (18) is connected and is installed in the outlet of collection medicine system (15) with pharmaceutical device (19), the outlet of pharmaceutical device (19) is connected transmission medicine finished product (17) with medicine travelling belt on the support (20); Travelling belt (16) is installed in the lower part outlet place of collection medicine system (15), is used for transmitting the Chinese medicine fine-grained particles of collection medicine system (15), is applicable to the device that more hold-up vessel (1) is installed.
4. the system of Chinese medicine flexibility electron formula according to claim 3, it is characterized in that comprising: hold-up vessel (1) structure is: go up at panel (7) hold-up vessel (1) is installed, fixing with securing member (34), the outlet of hold-up vessel (1) has sealing gasket (35), the bottom of sealing gasket (35) is operation valve (2), operation valve (2) lower end pipe is outer to be light source (38) and optoelectronic metering installation (4), hold-up vessel (1) is suitable for reading to be charging aperture (32), charging aperture (32) is fixing dry slot (33) on every side, and hold-up vessel (1) is suitable for reading to have top cover (31) to cover mouthful.Panel (7) and securing member (34) stationary storage jar (1).
5. according to the system of claim 3 or 4 described Chinese medicine flexibility electron formula, it is characterized in that:
System, control circuit comprises: total system is divided into three layers, and the superiors are that server passes through hub and can connect client computer/terminal (1A--nA) more than 100, supply with the doctor and use; Client computer/terminal (1A--nA) connects a plurality of unit controls circuit (MP) by server, system master computing machine (CPU) connected system bus;
Unit controls circuit (MP) comprising: system bus linkage unit control circuit single trigger (MP), and single trigger (MP) connects a plurality of cellular system buses, and each cellular system bus connects a plurality of hold-up vessels;
Hold-up vessel (1) control circuit comprises: (FD) light emitting source, phototriode (T), phototriode (T) connects amplifying circuit, amplifying circuit connects shaping circuit, and shaping circuit connects photoelectric metering control circuit (uP), photoelectric metering control circuit (uP) linkage unit system control bus.
The optoelectronic metering installation one-piece construction comprises: light emitting diode (FD), solenoid valve (DF) are installed on the conduit (40), and photoelectric metering control circuit (uP) connects solenoid valve (DF), and photoelectric metering control circuit (uP) is connected to system bus.
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| CN101028292B (en) * | 2007-03-31 | 2012-10-31 | 蔡诗伟 | Chinese-medicine prescription dosage method |
| CN101551955B (en) * | 2009-04-08 | 2014-10-22 | 无锡职业技术学院 | Practical training system and method for conveying uniform auxiliary materials |
| AU2013240207A1 (en) * | 2012-03-30 | 2014-09-18 | Baxter Corporation Englewood | Systems and methods for determining ingredient amounts for preparations for administration to patients |
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| CN1308945A (en) * | 2000-02-16 | 2001-08-22 | 梁颖然 | Computerized method for dispensing Chinese patent medicines to ensure constant components |
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Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1308945A (en) * | 2000-02-16 | 2001-08-22 | 梁颖然 | Computerized method for dispensing Chinese patent medicines to ensure constant components |
| CN1403822A (en) * | 2002-09-26 | 2003-03-19 | 浙江大学 | In-situ detection of product quality index in Chinese medicine production process |
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| Publication number | Publication date |
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| CN1484184A (en) | 2004-03-24 |
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